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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78614307
log Bayes Factor = 12.2775
Chromosome 19   position 5,790,540  (GRCh37) Explore rs78614307 on Ensembl!
Variant rs78614307 is part of Cluster X0028

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
Chapter II Neoplasms
0.980 0.020 0.000
Chapter V Mental and behavioural disorders
0.978 0.022 0.000
I47 Paroxysmal tachycardia
0.976 0.024 0.000
I05-I09 Chronic rheumatic heart diseases
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
I20-I25 Ischaemic heart diseases
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.969 0.031 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.967 0.033 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.967 0.033 0.000
I47.1 Supraventricular tachycardia
0.966 0.034 0.000
E00-E07 Disorders of thyroid gland
0.962 0.038 0.000
C64-C68 Malignant neoplasms of urinary tract
0.955 0.045 0.000
D60-D64 Aplastic and other anaemias
0.951 0.049 0.000
I20 Angina pectoris
0.951 0.049 0.000
C51-C58 Malignant neoplasms of female genital organs
0.949 0.051 0.000
Chapter VI Diseases of the nervous system
0.947 0.053 0.000
I08 Multiple valve diseases
0.946 0.054 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.944 0.056 0.000
I35 Nonrheumatic aortic valve disorders
0.938 0.062 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.933 0.067 0.000
I60-I69 Cerebrovascular diseases
0.931 0.069 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.929 0.071 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.928 0.072 0.000
E87.5 Hyperkalaemia
0.928 0.072 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.923 0.077 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.922 0.078 0.000
I20.9 Angina pectoris, unspecified
0.922 0.078 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.921 0.079 0.000
G30-G32 Other degenerative diseases of the nervous system
0.918 0.082 0.000
H60-H62 Diseases of external ear
0.918 0.082 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
S90-S99 Injuries to the ankle and foot
0.915 0.085 0.000
H90-H95 Other disorders of ear
0.915 0.085 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.906 0.094 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.905 0.095 0.000
E05.9 Thyrotoxicosis, unspecified
0.904 0.096 0.000
I51 Complications and ill-defined descriptions of heart disease
0.896 0.104 0.000
I08.0 Disorders of both mitral and aortic valves
0.895 0.105 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.889 0.111 0.000
E20-E35 Disorders of other endocrine glands
0.886 0.114 0.000
F00 Dementia in Alzheimer's disease
0.885 0.115 0.000
M86-M90 Other osteopathies
0.883 0.117 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.882 0.118 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.881 0.119 0.000
H90 Conductive and sensorineural hearing loss
0.881 0.119 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.880 0.120 0.000
E89.0 Postprocedural hypothyroidism
0.880 0.120 0.000
D64 Other anaemias
0.877 0.123 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.874 0.126 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.868 0.132 0.000
C34 Malignant neoplasm of bronchus and lung
0.867 0.133 0.000
G30 Alzheimer's disease
0.866 0.134 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.866 0.134 0.000
E40-E46 Malnutrition
0.861 0.139 0.000
I67 Other cerebrovascular diseases
0.856 0.144 0.000
I20.0 Unstable angina
0.854 0.146 0.000
I63 Cerebral infarction
0.854 0.146 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.851 0.149 0.000
E50-E64 Other nutritional deficiencies
0.851 0.149 0.000
D50-D53 Nutritional anaemias
0.850 0.150 0.000
I35.0 Aortic (valve) stenosis
0.847 0.153 0.000
C54 Malignant neoplasm of corpus uteri
0.846 0.154 0.000
I24 Other acute ischaemic heart diseases
0.846 0.154 0.000
T66-T78 Other and unspecified effects of external causes
0.846 0.154 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.846 0.154 0.000
H60 Otitis externa
0.845 0.155 0.000
H65-H75 Diseases of middle ear and mastoid
0.845 0.155 0.000
M50-M54 Other dorsopathies
0.839 0.161 0.000
S40-S49 Injuries to the shoulder and upper arm
0.839 0.161 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.836 0.164 0.000
I45 Other conduction disorders
0.834 0.166 0.000
S20-S29 Injuries to the thorax
0.833 0.167 0.000
E78.5 Hyperlipidaemia, unspecified
0.827 0.173 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.826 0.174 0.000
S10-S19 Injuries to the neck
0.825 0.175 0.000
M54 Dorsalgia
0.825 0.175 0.000
Chapter XXII Codes for special purposes
0.824 0.176 0.000
D64.9 Anaemia, unspecified
0.824 0.176 0.000
D48.1 Connective and other soft tissue
0.823 0.177 0.000
D61 Other aplastic anaemias
0.823 0.177 0.000
W00-W19 Falls
0.820 0.180 0.000
T43.2 Other and unspecified antidepressants
0.818 0.182 0.000
F01 Vascular dementia
0.816 0.184 0.000
F03 Unspecified dementia
0.816 0.184 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.815 0.185 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.814 0.186 0.000
C67 Malignant neoplasm of bladder
0.814 0.186 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.813 0.187 0.000
D63.0 Anaemia in neoplastic disease
0.811 0.189 0.000
S70-S79 Injuries to the hip and thigh
0.810 0.190 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.810 0.190 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.809 0.191 0.000
M54.5 Low back pain
0.807 0.193 0.000
M70-M79 Other soft tissue disorders
0.806 0.194 0.000
I67.9 Cerebrovascular disease, unspecified
0.805 0.195 0.000
E06 Thyroiditis
0.800 0.200 0.000
M89 Other disorders of bone
0.797 0.203 0.000
X20-X29 Contact with venomous animals and plants
0.795 0.205 0.000
V10-V19 Pedal cyclist injured in transport accident
0.795 0.205 0.000
G30.9 Alzheimer's disease, unspecified
0.794 0.206 0.000
S91 Open wound of ankle and foot
0.793 0.207 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.791 0.209 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.790 0.210 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.789 0.211 0.000
G90-G99 Other disorders of the nervous system
0.786 0.214 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.786 0.214 0.000
M05-M14 Inflammatory polyarthropathies
0.785 0.215 0.000
M54.56 Low back pain (Lumbar region)
0.784 0.216 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.784 0.216 0.000
D50 Iron deficiency anaemia
0.784 0.216 0.000
E87.0 Hyperosmolality and hypernatraemia
0.782 0.218 0.000
I08.8 Other multiple valve diseases
0.781 0.219 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.780 0.220 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.779 0.221 0.000
F02 Dementia in other diseases classified elsewhere
0.777 0.222 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.777 0.223 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.777 0.223 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
I07 Rheumatic tricuspid valve diseases
0.774 0.226 0.000
M75 Shoulder lesions
0.774 0.226 0.000
I78 Diseases of capillaries
0.774 0.226 0.000
F20 Schizophrenia
0.774 0.226 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.774 0.226 0.000
C54.1 Endometrium
0.773 0.227 0.000
I44 Atrioventricular and left bundle-branch block
0.772 0.228 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.772 0.228 0.000
C50-C50 Malignant neoplasm of breast
0.771 0.229 0.000
I35.8 Other aortic valve disorders
0.770 0.230 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.768 0.232 0.000
I37 Pulmonary valve disorders
0.767 0.233 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.233 0.000
C66 Malignant neoplasm of ureter
0.766 0.234 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.766 0.234 0.000
E87.7 Fluid overload
0.765 0.235 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.765 0.235 0.000
Chapter XIV Diseases of the genitourinary system
0.763 0.237 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.763 0.237 0.000
C52 Malignant neoplasm of vagina
0.762 0.238 0.000
E46 Unspecified protein-energy malnutrition
0.761 0.239 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.761 0.239 0.000
M75.0 Adhesive capsulitis of shoulder
0.758 0.242 0.000
E88 Other metabolic disorders
0.757 0.243 0.000
I46 Cardiac arrest
0.756 0.244 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
I05 Rheumatic mitral valve diseases
0.756 0.244 0.000
I51.0 Cardiac septal defect, acquired
0.756 0.244 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.754 0.246 0.000
C34.9 Bronchus or lung, unspecified
0.753 0.247 0.000
H73 Other disorders of tympanic membrane
0.753 0.247 0.000
E86 Volume depletion
0.752 0.247 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.751 0.249 0.000
I42 Cardiomyopathy
0.751 0.249 0.000
H90.5 Sensorineural hearing loss, unspecified
0.751 0.249 0.000
H90.2 Conductive hearing loss, unspecified
0.747 0.253 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.746 0.254 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.745 0.255 0.000
M60-M63 Disorders of muscles
0.745 0.255 0.000
Chapter XI Diseases of the digestive system
0.744 0.256 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.743 0.257 0.000
H61 Other disorders of external ear
0.743 0.257 0.000
D50.8 Other iron deficiency anaemias
0.742 0.258 0.000
G30.8 Other Alzheimer's disease
0.740 0.260 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.740 0.260 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.739 0.261 0.000
I35.9 Aortic valve disorder, unspecified
0.738 0.262 0.000
S80-S89 Injuries to the knee and lower leg
0.737 0.263 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
T78 Adverse effects, not elsewhere classified
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.737 0.263 0.000
S99 Other and unspecified injuries of ankle and foot
0.736 0.263 0.000
K70-K77 Diseases of liver
0.736 0.264 0.000
I73 Other peripheral vascular diseases
0.736 0.264 0.000
W20-W49 Exposure to inanimate mechanical forces
0.735 0.265 0.000
M88 Paget's disease of bone [osteitis deformans]
0.735 0.265 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.735 0.265 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.733 0.266 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.733 0.267 0.000
G20-G26 Extrapyramidal and movement disorders
0.733 0.267 0.000
M89.9 Disorder of bone, unspecified
0.733 0.267 0.000
C32 Malignant neoplasm of larynx
0.732 0.268 0.000
M65-M68 Disorders of synovium and tendon
0.732 0.268 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.732 0.268 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.732 0.268 0.000
D61.9 Aplastic anaemia, unspecified
0.731 0.268 0.000
H60.1 Cellulitis of external ear
0.731 0.269 0.000
M80-M85 Disorders of bone density and structure
0.730 0.270 0.000
E87.3 Alkalosis
0.729 0.270 0.000
N17-N19 Renal failure
0.728 0.272 0.000
C34.1 Upper lobe, bronchus or lung
0.728 0.272 0.000
N60-N64 Disorders of breast
0.727 0.273 0.000
I72 Other aneurysm
0.723 0.277 0.000
Y00-Y09 Assault
0.722 0.278 0.000
O85-O92 Complications predominantly related to the puerperium
0.720 0.280 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.720 0.280 0.000
I38 Endocarditis, valve unspecified
0.720 0.280 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.720 0.280 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.720 0.280 0.000
S27 Injury of other and unspecified intrathoracic organs
0.719 0.281 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.719 0.281 0.000
T63 Toxic effect of contact with venomous animals
0.719 0.281 0.000
I20.1 Angina pectoris with documented spasm
0.718 0.282 0.000
M54.9 Dorsalgia, unspecified
0.718 0.282 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
I51.9 Heart disease, unspecified
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
S00-S09 Injuries to the head
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
M86 Osteomyelitis
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.710 0.289 0.000
I62 Other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
E61 Deficiency of other nutrient elements
0.709 0.291 0.000
I47.0 Reentry ventricular arrhythmia
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
F01.9 Vascular dementia, unspecified
0.708 0.292 0.000
E87.4 Mixed disorder of acid-base balance
0.708 0.292 0.000
K76 Other diseases of liver
0.708 0.292 0.000
E22 Hyperfunction of pituitary gland
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.293 0.000
T36 Poisoning by systemic antibiotics
0.706 0.293 0.000
I71 Aortic aneurysm and dissection
0.706 0.294 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.705 0.295 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.705 0.295 0.000
F05.9 Delirium, unspecified
0.705 0.295 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.705 0.295 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.704 0.296 0.000
H74 Other disorders of middle ear and mastoid
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.701 0.299 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
I33 Acute and subacute endocarditis
0.701 0.299 0.000
I45.1 Other and unspecified right bundle-branch block
0.701 0.299 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.700 0.300 0.000
I09 Other rheumatic heart diseases
0.700 0.300 0.000
I06 Rheumatic aortic valve diseases
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.699 0.301 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.698 0.301 0.000
T79-T79 Certain early complications of trauma
0.698 0.302 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.698 0.302 0.000
F05.0 Delirium not superimposed on dementia, so described
0.698 0.302 0.000
O16 Unspecified maternal hypertension
0.698 0.302 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.697 0.303 0.000
Y43 Primarily systemic agents
0.697 0.303 0.000
H60.9 Otitis externa, unspecified
0.697 0.303 0.000
I51.4 Myocarditis, unspecified
0.697 0.303 0.000
Y44 Agents primarily affecting blood constituents
0.697 0.303 0.000
F22 Persistent delusional disorders
0.696 0.304 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.696 0.304 0.000
C34.3 Lower lobe, bronchus or lung
0.695 0.305 0.000
I51.8 Other ill-defined heart diseases
0.695 0.305 0.000
D48.7 Other specified sites
0.695 0.305 0.000
I23 Certain current complications following acute myocardial infarction
0.695 0.305 0.000
D55-D59 Haemolytic anaemias
0.695 0.305 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.694 0.306 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.694 0.306 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.693 0.306 0.000
F09 Unspecified organic or symptomatic mental disorder
0.693 0.306 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.693 0.306 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.693 0.307 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.692 0.308 0.000
G93 Other disorders of brain
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
M75.5 Bursitis of shoulder
0.690 0.310 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.690 0.310 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.689 0.311 0.000
E00 Congenital iodine-deficiency syndrome
0.689 0.311 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.689 0.311 0.000
I30 Acute pericarditis
0.689 0.311 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
T40.2 Other opioids
0.687 0.313 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.687 0.313 0.000
H73.8 Other specified disorders of tympanic membrane
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.686 0.314 0.000
C53 Malignant neoplasm of cervix uteri
0.686 0.314 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.685 0.315 0.000
S70 Superficial injury of hip and thigh
0.685 0.315 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.685 0.315 0.000
C65 Malignant neoplasm of renal pelvis
0.685 0.315 0.000
D47.4 Osteomyelofibrosis
0.684 0.316 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.682 0.318 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.682 0.318 0.000
F25 Schizoaffective disorders
0.681 0.319 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.680 0.320 0.000
C58 Malignant neoplasm of placenta
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
E04 Other non-toxic goitre
0.680 0.320 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.680 0.320 0.000
H93 Other disorders of ear, not elsewhere classified
0.680 0.320 0.000
E55 Vitamin D deficiency
0.678 0.322 0.000
I08.9 Multiple valve disease, unspecified
0.678 0.322 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.678 0.322 0.000
D44.3 Pituitary gland
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.323 0.000
S90 Superficial injury of ankle and foot
0.677 0.323 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.677 0.323 0.000
M13 Other arthritis
0.677 0.323 0.000
T43.9 Psychotropic drug, unspecified
0.677 0.323 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
T43.6 Psychostimulants with abuse potential
0.677 0.323 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.677 0.323 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.677 0.323 0.000
S80 Superficial injury of lower leg
0.677 0.323 0.000
T40.6 Other and unspecified narcotics
0.676 0.324 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
K65-K67 Diseases of peritoneum
0.675 0.325 0.000
W07 Fall involving chair
0.675 0.325 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.675 0.325 0.000
F60-F69 Disorders of adult personality and behaviour
0.675 0.325 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.674 0.325 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.674 0.326 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.674 0.326 0.000
G31.2 Degeneration of nervous system due to alcohol
0.673 0.327 0.000
F29 Unspecified nonorganic psychosis
0.672 0.327 0.000
I70 Atherosclerosis
0.671 0.329 0.000
I78.1 Naevus, nonneoplastic
0.671 0.329 0.000
F99-F99 Unspecified mental disorder
0.670 0.330 0.000
E05.8 Other thyrotoxicosis
0.669 0.331 0.000
E05.5 Thyroid crisis or storm
0.669 0.331 0.000
E05.4 Thyrotoxicosis factitia
0.669 0.331 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.669 0.331 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.669 0.331 0.000
N18 Chronic renal failure
0.668 0.332 0.000
E26 Hyperaldosteronism
0.668 0.332 0.000
C67.1 Dome of bladder
0.668 0.332 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.668 0.332 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.668 0.332 0.000
H60.8 Other otitis externa
0.667 0.332 0.000
X23 Contact with hornets, wasps and bees
0.666 0.334 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.666 0.334 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.666 0.334 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.666 0.334 0.000
E89.5 Postprocedural testicular hypofunction
0.666 0.334 0.000
E89.4 Postprocedural ovarian failure
0.666 0.334 0.000
E89.3 Postprocedural hypopituitarism
0.666 0.334 0.000
E89.1 Postprocedural hypoinsulinaemia
0.666 0.334 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
N19 Unspecified renal failure
0.666 0.334 0.000
S11 Open wound of neck
0.666 0.334 0.000
I67.8 Other specified cerebrovascular diseases
0.665 0.335 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.665 0.335 0.000
K70 Alcoholic liver disease
0.664 0.336 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.664 0.336 0.000
S91.0 Open wound of ankle
0.663 0.336 0.000
W10 Fall on and from stairs and steps
0.662 0.338 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.662 0.338 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.662 0.338 0.000
C31 Malignant neoplasm of accessory sinuses
0.662 0.338 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.662 0.338 0.000
C37 Malignant neoplasm of thymus
0.662 0.338 0.000
C33 Malignant neoplasm of trachea
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.661 0.339 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.339 0.000
Y58 Bacterial vaccines
0.661 0.339 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.339 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.339 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.339 0.000
E89.2 Postprocedural hypoparathyroidism
0.661 0.339 0.000
M87 Osteonecrosis
0.659 0.341 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.658 0.341 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.658 0.341 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.658 0.342 0.000
D80-D89 Certain disorders involving the immune mechanism
0.657 0.342 0.000
C51 Malignant neoplasm of vulva
0.657 0.343 0.000
T40.4 Other synthetic narcotics
0.657 0.343 0.000
Y57.9 Drug or medicament, unspecified
0.657 0.343 0.000
C67.9 Bladder, unspecified
0.656 0.344 0.000
T78.4 Allergy, unspecified
0.656 0.344 0.000
S98 Traumatic amputation of ankle and foot
0.656 0.344 0.000
S97 Crushing injury of ankle and foot
0.656 0.344 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.656 0.344 0.000
S95 Injury of blood vessels at ankle and foot level
0.656 0.344 0.000
S94 Injury of nerves at ankle and foot level
0.656 0.344 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.656 0.344 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.656 0.344 0.000
W22 Striking against or struck by other objects
0.656 0.344 0.000
I22 Subsequent myocardial infarction
0.656 0.344 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.654 0.346 0.000
I77 Other disorders of arteries and arterioles
0.654 0.346 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.654 0.346 0.000
C34.0 Main bronchus
0.653 0.347 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.651 0.349 0.000
T63.4 Venom of other arthropods
0.651 0.349 0.000
M54.1 Radiculopathy
0.651 0.349 0.000
M05 Seropositive rheumatoid arthritis
0.651 0.349 0.000
K76.6 Portal hypertension
0.650 0.350 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.650 0.350 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.650 0.350 0.000
K66 Other disorders of peritoneum
0.650 0.350 0.000
I44.0 Atrioventricular block, first degree
0.650 0.350 0.000
Y40 Systemic antibiotics
0.649 0.351 0.000
E06.3 Autoimmune thyroiditis
0.648 0.352 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.647 0.353 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.647 0.353 0.000
T46.1 Calcium-channel blockers
0.647 0.353 0.000
M00-M03 Infectious arthropathies
0.646 0.353 0.000
H61.2 Impacted cerumen
0.646 0.354 0.000
E78.4 Other hyperlipidaemia
0.645 0.355 0.000
Y54.5 Other diuretics
0.645 0.355 0.000
F20.9 Schizophrenia, unspecified
0.645 0.355 0.000
U80 Agent resistant to penicillin and related antibiotics
0.644 0.356 0.000
E34 Other endocrine disorders
0.643 0.357 0.000
I51.5 Myocardial degeneration
0.643 0.357 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.643 0.357 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.643 0.357 0.000
F02.3 Dementia in Parkinson's disease
0.642 0.358 0.000
D48.5 Skin
0.641 0.359 0.000
F43 Reaction to severe stress, and adjustment disorders
0.640 0.360 0.000
D46 Myelodysplastic syndromes
0.639 0.361 0.000
Y41.0 Sulphonamides
0.638 0.362 0.000
F23 Acute and transient psychotic disorders
0.638 0.362 0.000
F28 Other nonorganic psychotic disorders
0.638 0.362 0.000
F24 Induced delusional disorder
0.638 0.362 0.000
F21 Schizotypal disorder
0.638 0.362 0.000
C56 Malignant neoplasm of ovary
0.637 0.363 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.637 0.363 0.000
T23 Burn and corrosion of wrist and hand
0.636 0.364 0.000
F80-F89 Disorders of psychological development
0.635 0.364 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.635 0.364 0.000
E32 Diseases of thymus
0.635 0.364 0.000
E31 Polyglandular dysfunction
0.635 0.364 0.000
E30 Disorders of puberty, not elsewhere classified
0.635 0.364 0.000
E25 Adrenogenital disorders
0.635 0.364 0.000
E24 Cushing's syndrome
0.635 0.364 0.000
E20 Hypoparathyroidism
0.635 0.364 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.635 0.365 0.000
I24.8 Other forms of acute ischaemic heart disease
0.635 0.365 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.635 0.365 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.635 0.365 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.635 0.365 0.000
E21.3 Hyperparathyroidism, unspecified
0.633 0.367 0.000
F20.0 Paranoid schizophrenia
0.633 0.367 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.633 0.367 0.000
T31 Burns classified according to extent of body surface involved
0.633 0.367 0.000
Y52 Agents primarily affecting the cardiovascular system
0.633 0.367 0.000
S91.1 Open wound of toe(s) without damage to nail
0.633 0.367 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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