TreeWAS – Variant ID: rs78652542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter II Neoplasms	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.998	0.002
Chapter V Mental and behavioural disorders	0.995	0.005
I60-I69 Cerebrovascular diseases	0.990	0.010
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.984	0.016
K90-K93 Other diseases of the digestive system	0.981	0.019
Chapter XI Diseases of the digestive system	0.981	0.019
K92 Other diseases of digestive system	0.981	0.019
N80-N98 Noninflammatory disorders of female genital tract	0.981	0.019
Chapter XIV Diseases of the genitourinary system	0.980	0.020
Chapter VI Diseases of the nervous system	0.978	0.022
K70-K77 Diseases of liver	0.974	0.026
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.971	0.029
K92.2 Gastro-intestinal haemorrhage, unspecified	0.967	0.033
F30-F39 Mood [affective] disorders	0.963	0.037
C15-C26 Malignant neoplasms of digestive organs	0.962	0.038
A30-A49 Other bacterial diseases	0.961	0.039
S80-S89 Injuries to the knee and lower leg	0.959	0.041
I69 Sequelae of cerebrovascular disease	0.958	0.042
K70 Alcoholic liver disease	0.956	0.044
I95-I99 Other and unspecified disorders of the circulatory system	0.955	0.045
R50-R69 General symptoms and signs	0.954	0.046
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.951	0.049
I05-I09 Chronic rheumatic heart diseases	0.948	0.052
Chapter XII Diseases of the skin and subcutaneous tissue	0.945	0.055
C51-C58 Malignant neoplasms of female genital organs	0.944	0.056
D37-D48 Neoplasms of uncertain or unknown behaviour	0.942	0.058
S20-S29 Injuries to the thorax	0.942	0.058
S00-S09 Injuries to the head	0.942	0.058
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.941	0.059
R00 Abnormalities of heart beat	0.939	0.061
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.939	0.061
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.936	0.064
N88 Other noninflammatory disorders of cervix uteri	0.935	0.065
B35-B49 Mycoses	0.930	0.070
C18 Malignant neoplasm of colon	0.928	0.072
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.927	0.073
K92.1 Melaena	0.926	0.074
I67 Other cerebrovascular diseases	0.923	0.077
B95-B98 Bacterial, viral and other infectious agents	0.922	0.078
R00.0 Tachycardia, unspecified	0.921	0.079
G80-G83 Cerebral palsy and other paralytic syndromes	0.919	0.081
N87 Dysplasia of cervix uteri	0.917	0.083
I08 Multiple valve diseases	0.917	0.083
D00-D09 In situ neoplasms	0.917	0.083
R01 Cardiac murmurs and other cardiac sounds	0.916	0.084
I63 Cerebral infarction	0.915	0.085
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.914	0.086
N80 Endometriosis	0.912	0.088
N86 Erosion and ectropion of cervix uteri	0.909	0.091
F32 Depressive episode	0.909	0.091
R51 Headache	0.909	0.091
A41 Other septicaemia	0.900	0.100
L60-L75 Disorders of skin appendages	0.896	0.104
I95 Hypotension	0.896	0.104
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.893	0.107
F17 Mental and behavioural disorders due to use of tobacco	0.888	0.112
I80 Phlebitis and thrombophlebitis	0.887	0.113
R52 Pain, not elsewhere classified	0.885	0.115
N88.8 Other specified noninflammatory disorders of cervix uteri	0.880	0.120
L50-L54 Urticaria and erythema	0.880	0.120
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.879	0.121
R01.1 Cardiac murmur, unspecified	0.878	0.122
K70.9 Alcoholic liver disease, unspecified	0.872	0.128
B37 Candidiasis	0.871	0.129
A41.9 Septicaemia, unspecified	0.869	0.131
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.867	0.133
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.865	0.135
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.864	0.136
N94.6 Dysmenorrhoea, unspecified	0.859	0.141
R06 Abnormalities of breathing	0.859	0.141
K92.0 Haematemesis	0.859	0.141
N80.0 Endometriosis of uterus	0.858	0.142
C53 Malignant neoplasm of cervix uteri	0.858	0.142
D06 Carcinoma in situ of cervix uteri	0.857	0.143
G90-G99 Other disorders of the nervous system	0.857	0.143
Chapter XXI Factors influencing health status and contact with health services	0.856	0.144
S40-S49 Injuries to the shoulder and upper arm	0.855	0.145
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.853	0.147
I67.8 Other specified cerebrovascular diseases	0.851	0.149
G81 Hemiplegia	0.849	0.151
K70.3 Alcoholic cirrhosis of liver	0.848	0.152
R05 Cough	0.847	0.153
S01 Open wound of head	0.847	0.153
S27 Injury of other and unspecified intrathoracic organs	0.844	0.156
C64-C68 Malignant neoplasms of urinary tract	0.844	0.156
R20 Disturbances of skin sensation	0.844	0.156
S82 Fracture of lower leg, including ankle	0.844	0.156
C18.9 Colon, unspecified	0.837	0.163
A49 Bacterial infection of unspecified site	0.836	0.164
S90-S99 Injuries to the ankle and foot	0.836	0.164
N94.1 Dyspareunia	0.836	0.164
S80 Superficial injury of lower leg	0.836	0.164
C18.4 Transverse colon	0.836	0.164
R23 Other skin changes	0.835	0.165
F17.1 Harmful use	0.834	0.166
I95.1 Orthostatic hypotension	0.833	0.167
F33 Recurrent depressive disorder	0.831	0.169
N87.0 Mild cervical dysplasia	0.830	0.170
L72 Follicular cysts of skin and subcutaneous tissue	0.830	0.170
B97 Viral agents as the cause of diseases classified to other chapters	0.829	0.171
K72 Hepatic failure, not elsewhere classified	0.829	0.171
N84 Polyp of female genital tract	0.828	0.172
S30 Superficial injury of abdomen, lower back and pelvis	0.827	0.173
B25-B34 Other viral diseases	0.826	0.174
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.825	0.175
G50-G59 Nerve, nerve root and plexus disorders	0.824	0.176
D70-D77 Other diseases of blood and blood-forming organs	0.822	0.178
C16 Malignant neoplasm of stomach	0.822	0.178
N10-N16 Renal tubulo-interstitial diseases	0.821	0.179
L53 Other erythematous conditions	0.821	0.179
I85 Oesophageal varices	0.816	0.184
D06.9 Cervix, unspecified	0.815	0.185
Chapter XX External causes of morbidity and mortality	0.813	0.187
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.811	0.189
B37.8 Candidiasis of other sites	0.808	0.192
K91.4 Colostomy and enterostomy malfunction	0.808	0.192
D41.0 Kidney	0.808	0.192
N92 Excessive, frequent and irregular menstruation	0.808	0.192
R52.9 Pain, unspecified	0.807	0.193
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.805	0.195
K76 Other diseases of liver	0.805	0.195
R50 Fever of unknown origin	0.804	0.196
F32.3 Severe depressive episode with psychotic symptoms	0.802	0.198
Chapter VII Diseases of the eye and adnexa	0.799	0.201
G81.9 Hemiplegia, unspecified	0.799	0.201
A80-A89 Viral infections of the central nervous system	0.798	0.201
K92.9 Disease of digestive system, unspecified	0.798	0.202
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.798	0.202
C18.6 Descending colon	0.797	0.203
C53.9 Cervix uteri, unspecified	0.797	0.203
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.796	0.204
T79-T79 Certain early complications of trauma	0.791	0.208
K70.0 Alcoholic fatty liver	0.791	0.209
I98 Other disorders of circulatory system in diseases classified elsewhere	0.791	0.209
F80-F89 Disorders of psychological development	0.791	0.209
K70.4 Alcoholic hepatic failure	0.790	0.209
B65-B83 Helminthiases	0.790	0.210
I63.9 Cerebral infarction, unspecified	0.789	0.211
D60-D64 Aplastic and other anaemias	0.788	0.212
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.783	0.217
R06.8 Other and unspecified abnormalities of breathing	0.782	0.218
N87.1 Moderate cervical dysplasia	0.782	0.218
I08.8 Other multiple valve diseases	0.782	0.218
N80.3 Endometriosis of pelvic peritoneum	0.782	0.218
I87 Other disorders of veins	0.781	0.219
R03 Abnormal blood-pressure reading, without diagnosis	0.779	0.221
L53.9 Erythematous condition, unspecified	0.779	0.221
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.779	0.221
Chapter VIII Diseases of the ear and mastoid process	0.779	0.221
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.778	0.222
I08.1 Disorders of both mitral and tricuspid valves	0.778	0.222
I69.1 Sequelae of intracerebral haemorrhage	0.778	0.222
R54 Senility	0.776	0.224
F12 Mental and behavioural disorders due to use of cannabinoids	0.773	0.227
C57 Malignant neoplasm of other and unspecified female genital organs	0.773	0.227
I62 Other nontraumatic intracranial haemorrhage	0.773	0.227
N99-N99 Other disorders of the genitourinary system	0.772	0.228
G51 Facial nerve disorders	0.772	0.228
N87.2 Severe cervical dysplasia, not elsewhere classified	0.771	0.229
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.771	0.229
G70-G73 Diseases of myoneural junction and muscle	0.771	0.229
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.770	0.229
S05 Injury of eye and orbit	0.769	0.230
N85 Other noninflammatory disorders of uterus, except cervix	0.769	0.231
L60 Nail disorders	0.768	0.232
S29 Other and unspecified injuries of thorax	0.768	0.232
C19 Malignant neoplasm of rectosigmoid junction	0.767	0.233
G30-G32 Other degenerative diseases of the nervous system	0.767	0.233
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.767	0.233
R20.8 Other and unspecified disturbances of skin sensation	0.765	0.235
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.764	0.236
I30-I52 Other forms of heart disease	0.764	0.236
T15-T19 Effects of foreign body entering through natural orifice	0.763	0.237
S22 Fracture of rib(s), sternum and thoracic spine	0.762	0.238
S02 Fracture of skull and facial bones	0.761	0.239
R60 Oedema, not elsewhere classified	0.761	0.239
I67.0 Dissection of cerebral arteries, nonruptured	0.760	0.240
B37.0 Candidal stomatitis	0.759	0.241
Chapter XXII Codes for special purposes	0.759	0.241
I67.2 Cerebral atherosclerosis	0.758	0.242
S27.0 Traumatic pneumothorax	0.758	0.242
Z29 Need for other prophylactic measures	0.757	0.243
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.756	0.243
A49.0 Staphylococcal infection, unspecified	0.756	0.244
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.754	0.246
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.754	0.246
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.753	0.247
A50-A64 Infections with a predominantly sexual mode of transmission	0.749	0.251
F10 Mental and behavioural disorders due to use of alcohol	0.749	0.251
Z22 Carrier of infectious disease	0.749	0.251
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.749	0.251
C17 Malignant neoplasm of small intestine	0.749	0.251
S89 Other and unspecified injuries of lower leg	0.748	0.252
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.748	0.252
I69.3 Sequelae of cerebral infarction	0.747	0.253
F99-F99 Unspecified mental disorder	0.746	0.254
C18.5 Splenic flexure	0.746	0.254
I51 Complications and ill-defined descriptions of heart disease	0.745	0.255
K74 Fibrosis and cirrhosis of liver	0.745	0.255
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.743	0.257
L72.0 Epidermal cyst	0.743	0.257
F32.9 Depressive episode, unspecified	0.743	0.257
G82 Paraplegia and tetraplegia	0.743	0.257
R58 Haemorrhage, not elsewhere classified	0.741	0.259
C55 Malignant neoplasm of uterus, part unspecified	0.741	0.259
R63 Symptoms and signs concerning food and fluid intake	0.741	0.259
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.737	0.263
S82.4 Fracture of fibula alone	0.734	0.266
S32 Fracture of lumbar spine and pelvis	0.733	0.267
F40-F48 Neurotic, stress-related and somatoform disorders	0.732	0.267
I95.0 Idiopathic hypotension	0.732	0.268
N92.3 Ovulation bleeding	0.731	0.269
A41.1 Septicaemia due to other specified staphylococcus	0.731	0.269
R21 Rash and other nonspecific skin eruption	0.730	0.270
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.729	0.270
C56 Malignant neoplasm of ovary	0.729	0.270
A00-A09 Intestinal infectious diseases	0.729	0.271
F31 Bipolar affective disorder	0.728	0.272
H40-H42 Glaucoma	0.727	0.273
G00-G09 Inflammatory diseases of the central nervous system	0.726	0.274
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.726	0.274
S70-S79 Injuries to the hip and thigh	0.726	0.274
N84.0 Polyp of corpus uteri	0.725	0.275
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.725	0.275
S09 Other and unspecified injuries of head	0.725	0.275
C15 Malignant neoplasm of oesophagus	0.724	0.276
N88.2 Stricture and stenosis of cervix uteri	0.722	0.278
D41.4 Bladder	0.721	0.279
D07 Carcinoma in situ of other and unspecified genital organs	0.721	0.279
D70 Agranulocytosis	0.721	0.279
R00.2 Palpitations	0.721	0.279
I99 Other and unspecified disorders of circulatory system	0.720	0.280
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.720	0.280
F32.2 Severe depressive episode without psychotic symptoms	0.720	0.280
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.719	0.281
N60-N64 Disorders of breast	0.719	0.281
R50.9 Fever, unspecified	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.283
G54 Nerve root and plexus disorders	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
B99-B99 Other infectious diseases	0.716	0.284
B90-B94 Sequelae of infectious and parasitic diseases	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B50-B64 Protozoal diseases	0.716	0.284
B20-B24 Human immunodeficiency virus [HIV] disease	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
A15-A19 Tuberculosis	0.716	0.284
N92.6 Irregular menstruation, unspecified	0.716	0.284
S49 Other and unspecified injuries of shoulder and upper arm	0.715	0.285
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.714	0.286
R52.2 Other chronic pain	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
F60-F69 Disorders of adult personality and behaviour	0.713	0.287
G93 Other disorders of brain	0.713	0.287
C16.0 Cardia	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
R23.8 Other and unspecified skin changes	0.712	0.288
N10 Acute tubulo-interstitial nephritis	0.712	0.288
K76.6 Portal hypertension	0.712	0.288
C71 Malignant neoplasm of brain	0.711	0.289
C67 Malignant neoplasm of bladder	0.711	0.289
I68 Cerebrovascular disorders in diseases classified elsewhere	0.710	0.290
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.710	0.290
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.710	0.290
I51.7 Cardiomegaly	0.709	0.291
B49 Unspecified mycosis	0.709	0.291
G51.0 Bell's palsy	0.709	0.291
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.291
R06.1 Stridor	0.709	0.291
Y43 Primarily systemic agents	0.708	0.292
K72.9 Hepatic failure, unspecified	0.708	0.292
R57 Shock, not elsewhere classified	0.707	0.293
F33.9 Recurrent depressive disorder, unspecified	0.707	0.293
D45 Polycythaemia vera	0.707	0.293
I95.9 Hypotension, unspecified	0.706	0.294
A46 Erysipelas	0.706	0.294
R95-R99 Ill-defined and unknown causes of mortality	0.705	0.294
K93 Disorders of other digestive organs in diseases classified elsewhere	0.704	0.296
K92.8 Other specified diseases of digestive system	0.703	0.297
N98 Complications associated with artificial fertilisation	0.703	0.297
N91 Absent, scanty and rare menstruation	0.703	0.297
N82 Fistulae involving female genital tract	0.703	0.297
N96 Habitual aborter	0.703	0.297
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.703	0.297
F32.1 Moderate depressive episode	0.701	0.299
Z22.3 Carrier of other specified bacterial diseases	0.700	0.300
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.700	0.300
G58 Other mononeuropathies	0.699	0.301
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.699	0.301
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.698	0.302
K77 Liver disorders in diseases classified elsewhere	0.698	0.302
K73 Chronic hepatitis, not elsewhere classified	0.698	0.302
K71 Toxic liver disease	0.698	0.302
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.697	0.303
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.697	0.303
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.696	0.304
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.695	0.305
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.695	0.305
N92.4 Excessive bleeding in the premenopausal period	0.695	0.305
I85.9 Oesophageal varices without bleeding	0.693	0.307
L00-L08 Infections of the skin and subcutaneous tissue	0.693	0.307
R53 Malaise and fatigue	0.692	0.308
C18.3 Hepatic flexure	0.692	0.308
S80.0 Contusion of knee	0.691	0.309
R23.3 Spontaneous ecchymoses	0.691	0.309
F38 Other mood [affective] disorders	0.691	0.309
F34 Persistent mood [affective] disorders	0.691	0.309
F30 Manic episode	0.691	0.309
F39 Unspecified mood [affective] disorder	0.691	0.309
S42 Fracture of shoulder and upper arm	0.690	0.310
S20 Superficial injury of thorax	0.690	0.310
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.689	0.310
C21 Malignant neoplasm of anus and anal canal	0.689	0.310
C23 Malignant neoplasm of gallbladder	0.689	0.310
N13 Obstructive and reflux uropathy	0.690	0.310
A48 Other bacterial diseases, not elsewhere classified	0.689	0.311
A44 Bartonellosis	0.689	0.311
A43 Nocardiosis	0.689	0.311
A42 Actinomycosis	0.689	0.311
A40 Streptococcal septicaemia	0.689	0.311
A39 Meningococcal infection	0.689	0.311
A37 Whooping cough	0.689	0.311
A36 Diphtheria	0.689	0.311
A32 Listeriosis	0.689	0.311
A31 Infection due to other mycobacteria	0.689	0.311
A30 Leprosy [Hansen's disease]	0.689	0.311
A38 Scarlet fever	0.689	0.311
A35 Other tetanus	0.689	0.311
A34 Obstetrical tetanus	0.689	0.311
A33 Tetanus neonatorum	0.689	0.311
I86 Varicose veins of other sites	0.689	0.311
B15-B19 Viral hepatitis	0.689	0.311
I81 Portal vein thrombosis	0.688	0.312
S88 Traumatic amputation of lower leg	0.687	0.313
S87 Crushing injury of lower leg	0.687	0.313
S86 Injury of muscle and tendon at lower leg level	0.687	0.313
S85 Injury of blood vessels at lower leg level	0.687	0.313
S84 Injury of nerves at lower leg level	0.687	0.313
S01.2 Open wound of nose	0.687	0.313
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.687	0.313
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.687	0.313
I69.0 Sequelae of subarachnoid haemorrhage	0.687	0.313
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.686	0.314
D73 Diseases of spleen	0.686	0.314
G83 Other paralytic syndromes	0.686	0.314
K70.2 Alcoholic fibrosis and sclerosis of liver	0.686	0.314
K70.1 Alcoholic hepatitis	0.686	0.314
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.685	0.315
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.685	0.315
S81 Open wound of lower leg	0.685	0.315
L71 Rosacea	0.684	0.316
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.684	0.316
R62 Lack of expected normal physiological development	0.684	0.316
R64 Cachexia	0.684	0.316
I42 Cardiomyopathy	0.684	0.316
N90 Other noninflammatory disorders of vulva and perineum	0.683	0.316
L50 Urticaria	0.682	0.318
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.682	0.318
F18 Mental and behavioural disorders due to use of volatile solvents	0.682	0.318
F16 Mental and behavioural disorders due to use of hallucinogens	0.682	0.318
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.682	0.318
F14 Mental and behavioural disorders due to use of cocaine	0.682	0.318
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.682	0.318
F11 Mental and behavioural disorders due to use of opioids	0.682	0.318
I09 Other rheumatic heart diseases	0.680	0.320
I06 Rheumatic aortic valve diseases	0.680	0.320
C26 Malignant neoplasm of other and ill-defined digestive organs	0.679	0.321
S01.1 Open wound of eyelid and periocular area	0.678	0.321
I07 Rheumatic tricuspid valve diseases	0.678	0.322
L10-L14 Bullous disorders	0.678	0.322
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.677	0.322
C51 Malignant neoplasm of vulva	0.677	0.323
C58 Malignant neoplasm of placenta	0.677	0.323
C52 Malignant neoplasm of vagina	0.677	0.323
N85.2 Hypertrophy of uterus	0.677	0.323
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.676	0.324
S80.9 Superficial injury of lower leg, unspecified	0.676	0.324
D47.2 Monoclonal gammopathy	0.676	0.324
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.675	0.324
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.675	0.324
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.675	0.324
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.675	0.324
F17.2 Dependence syndrome	0.675	0.325
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.675	0.325
S26 Injury of heart	0.675	0.325
S25 Injury of blood vessels of thorax	0.675	0.325
S24 Injury of nerves and spinal cord at thorax level	0.675	0.325
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.675	0.325
S21 Open wound of thorax	0.675	0.325
S08 Traumatic amputation of part of head	0.675	0.325
S07 Crushing injury of head	0.675	0.325
S04 Injury of cranial nerves	0.675	0.325
S03 Dislocation, sprain and strain of joints and ligaments of head	0.675	0.325
H40 Glaucoma	0.675	0.325
C69 Malignant neoplasm of eye and adnexa	0.675	0.325
D61 Other aplastic anaemias	0.674	0.325
N94.5 Secondary dysmenorrhoea	0.674	0.326
N94.4 Primary dysmenorrhoea	0.674	0.326
N94.3 Premenstrual tension syndrome	0.674	0.326
N94.2 Vaginismus	0.674	0.326
N94.0 Mittelschmerz	0.674	0.326
R06.5 Mouth breathing	0.674	0.326
R52.0 Acute pain	0.674	0.326
I88 Nonspecific lymphadenitis	0.673	0.326
I98.2 Oesophageal varices in diseases classified elsewhere	0.673	0.327
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.672	0.328
D47.3 Essential (haemorrhagic) thrombocythaemia	0.671	0.329
G35-G37 Demyelinating diseases of the central nervous system	0.671	0.329
S82.2 Fracture of shaft of tibia	0.671	0.329
Z70-Z76 Persons encountering health services in other circumstances	0.671	0.329
S06 Intracranial injury	0.670	0.329
N88.4 Hypertrophic elongation of cervix uteri	0.670	0.330
N88.3 Incompetence of cervix uteri	0.670	0.330
N88.1 Old laceration of cervix uteri	0.670	0.330
N88.0 Leukoplakia of cervix uteri	0.670	0.330
N25-N29 Other disorders of kidney and ureter	0.669	0.331
Chapter IV Endocrine, nutritional and metabolic diseases	0.669	0.331
D05 Carcinoma in situ of breast	0.668	0.332
F32.0 Mild depressive episode	0.668	0.332
F10.2 Dependence syndrome	0.667	0.333
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.667	0.333
K65-K67 Diseases of peritoneum	0.667	0.333
B48 Other mycoses, not elsewhere classified	0.667	0.333
B47 Mycetoma	0.667	0.333
B46 Zygomycosis	0.667	0.333
B45 Cryptococcosis	0.667	0.333
B44 Aspergillosis	0.667	0.333
B43 Chromomycosis and phaeomycotic abscess	0.667	0.333
B42 Sporotrichosis	0.667	0.333
B41 Paracoccidioidomycosis	0.667	0.333
B40 Blastomycosis	0.667	0.333
B39 Histoplasmosis	0.667	0.333
B38 Coccidioidomycosis	0.667	0.333
B36 Other superficial mycoses	0.667	0.333
B35 Dermatophytosis	0.667	0.333
C73 Malignant neoplasm of thyroid gland	0.667	0.333
Z93 Artificial opening status	0.666	0.334
C18.8 Overlapping lesion of colon	0.665	0.335
C18.1 Appendix	0.665	0.335
R06.4 Hyperventilation	0.665	0.335
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.664	0.335
S37 Injury of urinary and pelvic organs	0.664	0.335
S36 Injury of intra-abdominal organs	0.664	0.335
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.664	0.335
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.664	0.335
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.664	0.335
S31 Open wound of abdomen, lower back and pelvis	0.664	0.335
D75 Other diseases of blood and blood-forming organs	0.663	0.337
D64 Other anaemias	0.663	0.337
S90 Superficial injury of ankle and foot	0.663	0.337
K75 Other inflammatory liver diseases	0.662	0.338
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.662	0.338
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.662	0.338
I67.7 Cerebral arteritis, not elsewhere classified	0.662	0.338
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.662	0.338
I67.5 Moyamoya disease	0.662	0.338
I67.4 Hypertensive encephalopathy	0.662	0.338
I67.3 Progressive vascular leukoencephalopathy	0.662	0.338
S01.8 Open wound of other parts of head	0.662	0.338
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.661	0.339
B34 Viral infection of unspecified site	0.661	0.339
D09 Carcinoma in situ of other and unspecified sites	0.660	0.340
S82.0 Fracture of patella	0.659	0.341
G90 Disorders of autonomic nervous system	0.659	0.341
G80 Infantile cerebral palsy	0.659	0.341
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.658	0.342
I08.9 Multiple valve disease, unspecified	0.658	0.342
I08.2 Disorders of both aortic and tricuspid valves	0.658	0.342
D02 Carcinoma in situ of middle ear and respiratory system	0.657	0.343
D01 Carcinoma in situ of other and unspecified digestive organs	0.657	0.343
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.657	0.343
R01.2 Other cardiac sounds	0.657	0.343
R01.0 Benign and innocent cardiac murmurs	0.657	0.343
I63.8 Other cerebral infarction	0.656	0.344
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.656	0.344
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.656	0.344
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.656	0.344
A87 Viral meningitis	0.655	0.345
Y43.3 Other antineoplastic drugs	0.655	0.345
S82.40 Fracture of fibula alone (closed)	0.655	0.345
H90-H95 Other disorders of ear	0.654	0.346
Z29.0 Isolation	0.654	0.346
N80.6 Endometriosis in cutaneous scar	0.654	0.346
N80.5 Endometriosis of intestine	0.654	0.346
N80.4 Endometriosis of rectovaginal septum and vagina	0.654	0.346

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations