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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78766240
log Bayes Factor = 19.5029
Chromosome 3   position 12,067,966  (GRCh37) Explore rs78766240 on Ensembl!
Variant rs78766240 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
I20 Angina pectoris
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.996 0.004 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.996 0.004 0.000
N10-N16 Renal tubulo-interstitial diseases
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
E78.0 Pure hypercholesterolaemia
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
I20.9 Angina pectoris, unspecified
0.992 0.008 0.000
Z88.2 Personal history of allergy to sulphonamides
0.982 0.018 0.000
N13 Obstructive and reflux uropathy
0.981 0.019 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.970 0.030 0.000
Chapter X Diseases of the respiratory system
0.969 0.031 0.000
E11 Non-insulin-dependent diabetes mellitus
0.966 0.034 0.000
J30-J39 Other diseases of upper respiratory tract
0.964 0.036 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.957 0.043 0.000
Chapter XI Diseases of the digestive system
0.957 0.043 0.000
Z88.6 Personal history of allergy to analgesic agent
0.956 0.044 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.954 0.046 0.000
N84 Polyp of female genital tract
0.952 0.048 0.000
I30-I52 Other forms of heart disease
0.951 0.049 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.951 0.049 0.000
J33 Nasal polyp
0.949 0.051 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.948 0.052 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.943 0.057 0.000
N84.1 Polyp of cervix uteri
0.943 0.057 0.000
B95-B98 Bacterial, viral and other infectious agents
0.942 0.058 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.939 0.061 0.000
Z93 Artificial opening status
0.939 0.061 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.930 0.070 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.928 0.072 0.000
E10 Insulin-dependent diabetes mellitus
0.926 0.074 0.000
Z83 Family history of other specific disorders
0.925 0.075 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.923 0.077 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.922 0.078 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.918 0.082 0.000
J34 Other disorders of nose and nasal sinuses
0.916 0.084 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.912 0.088 0.000
I35 Nonrheumatic aortic valve disorders
0.912 0.088 0.000
Chapter VII Diseases of the eye and adnexa
0.910 0.090 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.904 0.096 0.000
J33.0 Polyp of nasal cavity
0.904 0.096 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.903 0.097 0.000
K70-K77 Diseases of liver
0.903 0.097 0.000
C15-C26 Malignant neoplasms of digestive organs
0.900 0.100 0.000
N30-N39 Other diseases of urinary system
0.899 0.101 0.000
N84.0 Polyp of corpus uteri
0.895 0.105 0.000
E11.9 Without complications
0.893 0.107 0.000
J34.3 Hypertrophy of nasal turbinates
0.893 0.107 0.000
S40-S49 Injuries to the shoulder and upper arm
0.891 0.109 0.000
Z93.2 Ileostomy status
0.891 0.109 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.883 0.117 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.883 0.117 0.000
E78.5 Hyperlipidaemia, unspecified
0.876 0.124 0.000
B35-B49 Mycoses
0.875 0.125 0.000
E83 Disorders of mineral metabolism
0.871 0.129 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.869 0.131 0.000
H30-H36 Disorders of choroid and retina
0.868 0.132 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.868 0.132 0.000
N86 Erosion and ectropion of cervix uteri
0.865 0.135 0.000
E11.3 With ophthalmic complications
0.864 0.136 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.864 0.136 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.862 0.138 0.000
J33.8 Other polyp of sinus
0.861 0.139 0.000
K65-K67 Diseases of peritoneum
0.858 0.142 0.000
Z83.7 Family history of diseases of the digestive system
0.857 0.143 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.856 0.144 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.854 0.146 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.854 0.146 0.000
Chapter VIII Diseases of the ear and mastoid process
0.852 0.148 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.852 0.148 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.852 0.148 0.000
S90-S99 Injuries to the ankle and foot
0.849 0.151 0.000
Z89 Acquired absence of limb
0.845 0.155 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.843 0.157 0.000
S20-S29 Injuries to the thorax
0.840 0.160 0.000
E50-E64 Other nutritional deficiencies
0.840 0.160 0.000
I05-I09 Chronic rheumatic heart diseases
0.839 0.161 0.000
C80 Malignant neoplasm without specification of site
0.839 0.161 0.000
N39 Other disorders of urinary system
0.838 0.162 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.837 0.163 0.000
K86 Other diseases of pancreas
0.836 0.164 0.000
C34 Malignant neoplasm of bronchus and lung
0.836 0.164 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.835 0.165 0.000
K83 Other diseases of biliary tract
0.834 0.166 0.000
I35.0 Aortic (valve) stenosis
0.833 0.167 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.833 0.167 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.831 0.169 0.000
N95 Menopausal and other perimenopausal disorders
0.830 0.170 0.000
Chapter XXII Codes for special purposes
0.828 0.172 0.000
I25.1 Atherosclerotic heart disease
0.827 0.173 0.000
D00-D09 In situ neoplasms
0.822 0.178 0.000
N99-N99 Other disorders of the genitourinary system
0.820 0.180 0.000
N13.3 Other and unspecified hydronephrosis
0.818 0.182 0.000
T82.1 Mechanical complication of cardiac electronic device
0.815 0.185 0.000
I35.1 Aortic (valve) insufficiency
0.810 0.190 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.808 0.192 0.000
B37 Candidiasis
0.807 0.193 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.806 0.194 0.000
I42 Cardiomyopathy
0.801 0.199 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.800 0.200 0.000
H35 Other retinal disorders
0.799 0.201 0.000
I20.0 Unstable angina
0.798 0.202 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.798 0.202 0.000
H36 Retinal disorders in diseases classified elsewhere
0.798 0.202 0.000
K70 Alcoholic liver disease
0.797 0.203 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
N60-N64 Disorders of breast
0.797 0.203 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.795 0.205 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.794 0.206 0.000
C51-C58 Malignant neoplasms of female genital organs
0.794 0.206 0.000
C25 Malignant neoplasm of pancreas
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.793 0.207 0.000
T66-T78 Other and unspecified effects of external causes
0.793 0.207 0.000
N73 Other female pelvic inflammatory diseases
0.792 0.208 0.000
T87 Complications peculiar to reattachment and amputation
0.791 0.209 0.000
K76 Other diseases of liver
0.790 0.210 0.000
Z34 Supervision of normal pregnancy
0.790 0.210 0.000
E10.3 With ophthalmic complications
0.788 0.212 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.786 0.214 0.000
I20.8 Other forms of angina pectoris
0.785 0.215 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.785 0.215 0.000
E10.9 Without complications
0.784 0.216 0.000
E10.4 With neurological complications
0.784 0.216 0.000
I20.1 Angina pectoris with documented spasm
0.780 0.220 0.000
I31 Other diseases of pericardium
0.780 0.220 0.000
H10-H13 Disorders of conjunctiva
0.779 0.221 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.777 0.223 0.000
C18 Malignant neoplasm of colon
0.777 0.223 0.000
N10 Acute tubulo-interstitial nephritis
0.775 0.225 0.000
S60-S69 Injuries to the wrist and hand
0.775 0.225 0.000
Y52 Agents primarily affecting the cardiovascular system
0.775 0.225 0.000
J95-J99 Other diseases of the respiratory system
0.775 0.225 0.000
J32 Chronic sinusitis
0.774 0.226 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.774 0.226 0.000
I22 Subsequent myocardial infarction
0.772 0.228 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.772 0.228 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.771 0.229 0.000
J35 Chronic diseases of tonsils and adenoids
0.771 0.229 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.770 0.230 0.000
N39.3 Stress incontinence
0.770 0.230 0.000
C50-C50 Malignant neoplasm of breast
0.767 0.233 0.000
N39.0 Urinary tract infection, site not specified
0.767 0.233 0.000
K83.1 Obstruction of bile duct
0.765 0.235 0.000
N70 Salpingitis and oophoritis
0.764 0.236 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.763 0.236 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.762 0.238 0.000
W50-W64 Exposure to animate mechanical forces
0.762 0.238 0.000
K81 Cholecystitis
0.761 0.239 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.761 0.239 0.000
Z95.4 Presence of other heart-valve replacement
0.760 0.240 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.759 0.240 0.000
D37.4 Colon
0.758 0.242 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
E78.2 Mixed hyperlipidaemia
0.755 0.245 0.000
H65-H75 Diseases of middle ear and mastoid
0.754 0.246 0.000
C79 Secondary malignant neoplasm of other sites
0.754 0.246 0.000
T79-T79 Certain early complications of trauma
0.753 0.247 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.753 0.247 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.751 0.249 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.751 0.249 0.000
Chapter V Mental and behavioural disorders
0.750 0.249 0.000
D37.5 Rectum
0.749 0.251 0.000
E40-E46 Malnutrition
0.749 0.251 0.000
N13.4 Hydroureter
0.749 0.251 0.000
K66 Other disorders of peritoneum
0.748 0.252 0.000
H36.0 Diabetic retinopathy
0.748 0.252 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.747 0.253 0.000
E11.5 With peripheral circulatory complications
0.747 0.253 0.000
N95.0 Postmenopausal bleeding
0.747 0.253 0.000
C80.9 Malignant neoplasm, unspecified
0.747 0.253 0.000
B37.8 Candidiasis of other sites
0.747 0.253 0.000
Z88.5 Personal history of allergy to narcotic agent
0.746 0.254 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.746 0.254 0.000
I38 Endocarditis, valve unspecified
0.746 0.254 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.745 0.255 0.000
Z93.5 Cystostomy status
0.745 0.255 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.743 0.257 0.000
E14 Unspecified diabetes mellitus
0.743 0.257 0.000
E11.4 With neurological complications
0.742 0.258 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.741 0.259 0.000
B15-B19 Viral hepatitis
0.741 0.259 0.000
K04 Diseases of pulp and periapical tissues
0.740 0.260 0.000
N30 Cystitis
0.739 0.261 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.739 0.261 0.000
J33.9 Nasal polyp, unspecified
0.739 0.261 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.738 0.262 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.738 0.262 0.000
Y43 Primarily systemic agents
0.737 0.263 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.737 0.263 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.737 0.263 0.000
N00-N08 Glomerular diseases
0.735 0.265 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.735 0.265 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.735 0.265 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.734 0.265 0.000
L20-L30 Dermatitis and eczema
0.734 0.266 0.000
S42 Fracture of shoulder and upper arm
0.733 0.267 0.000
I25.2 Old myocardial infarction
0.733 0.267 0.000
K85 Acute pancreatitis
0.733 0.267 0.000
Z83.5 Family history of eye and ear disorders
0.732 0.268 0.000
C78.0 Secondary malignant neoplasm of lung
0.731 0.269 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.731 0.269 0.000
Z93.3 Colostomy status
0.730 0.270 0.000
E53 Deficiency of other B group vitamins
0.727 0.273 0.000
S70-S79 Injuries to the hip and thigh
0.726 0.274 0.000
N88 Other noninflammatory disorders of cervix uteri
0.725 0.275 0.000
I95 Hypotension
0.725 0.275 0.000
O00-O08 Pregnancy with abortive outcome
0.724 0.276 0.000
Y86 Sequelae of other accidents
0.724 0.276 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.724 0.276 0.000
Z36 Antenatal screening
0.723 0.277 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.723 0.277 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.721 0.279 0.000
E83.5 Disorders of calcium metabolism
0.721 0.279 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.720 0.280 0.000
N76 Other inflammation of vagina and vulva
0.720 0.280 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.720 0.280 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.719 0.281 0.000
A80-A89 Viral infections of the central nervous system
0.719 0.281 0.000
N25-N29 Other disorders of kidney and ureter
0.719 0.281 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.718 0.282 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.717 0.282 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.283 0.000
I25.4 Coronary artery aneurysm
0.716 0.283 0.000
I25.3 Aneurysm of heart
0.716 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
S40 Superficial injury of shoulder and upper arm
0.715 0.285 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.715 0.285 0.000
I46 Cardiac arrest
0.714 0.286 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.714 0.286 0.000
E78.8 Other disorders of lipoprotein metabolism
0.714 0.286 0.000
E78.6 Lipoprotein deficiency
0.714 0.286 0.000
E78.4 Other hyperlipidaemia
0.714 0.286 0.000
E78.3 Hyperchylomicronaemia
0.714 0.286 0.000
E78.1 Pure hyperglyceridaemia
0.714 0.286 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.713 0.287 0.000
N15 Other renal tubulo-interstitial diseases
0.713 0.287 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.713 0.287 0.000
N11 Chronic tubulo-interstitial nephritis
0.713 0.287 0.000
N13.8 Other obstructive and reflux uropathy
0.713 0.287 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.712 0.288 0.000
K86.8 Other specified diseases of pancreas
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.711 0.288 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.288 0.000
Z95.2 Presence of prosthetic heart valve
0.711 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.711 0.289 0.000
S91 Open wound of ankle and foot
0.711 0.289 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
K09 Cysts of oral region, not elsewhere classified
0.710 0.290 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.710 0.290 0.000
D37.7 Other digestive organs
0.710 0.290 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.708 0.292 0.000
K14 Diseases of tongue
0.708 0.292 0.000
C34.0 Main bronchus
0.707 0.293 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.707 0.293 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.705 0.295 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.704 0.296 0.000
C34.3 Lower lobe, bronchus or lung
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.703 0.297 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.703 0.297 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.703 0.297 0.000
N13.6 Pyonephrosis
0.703 0.297 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.703 0.297 0.000
H35.8 Other specified retinal disorders
0.703 0.297 0.000
D47.2 Monoclonal gammopathy
0.703 0.297 0.000
K65 Peritonitis
0.702 0.298 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.702 0.298 0.000
I49 Other cardiac arrhythmias
0.701 0.299 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.701 0.299 0.000
K75 Other inflammatory liver diseases
0.700 0.300 0.000
V10-V19 Pedal cyclist injured in transport accident
0.700 0.300 0.000
N72 Inflammatory disease of cervix uteri
0.700 0.300 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.700 0.300 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.300 0.000
Y10-Y34 Event of undetermined intent
0.699 0.300 0.000
Y00-Y09 Assault
0.699 0.300 0.000
X85-X99 Assault
0.699 0.300 0.000
X50-X57 Overexertion, travel and privation
0.699 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.699 0.300 0.000
X30-X39 Exposure to forces of nature
0.699 0.300 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.300 0.000
X10-X19 Contact with heat and hot substances
0.699 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.300 0.000
W75-W84 Other accidental threats to breathing
0.699 0.300 0.000
W65-W74 Accidental drowning and submersion
0.699 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.300 0.000
V95-V97 Air and space transport accidents
0.699 0.300 0.000
V90-V94 Water transport accidents
0.699 0.300 0.000
V80-V89 Other land transport accidents
0.699 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.300 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
N93 Other abnormal uterine and vaginal bleeding
0.699 0.301 0.000
I08 Multiple valve diseases
0.699 0.301 0.000
Z39 Postpartum care and examination
0.698 0.302 0.000
H65 Nonsuppurative otitis media
0.698 0.302 0.000
Z89.5 Acquired absence of leg at or below knee
0.698 0.302 0.000
E83.4 Disorders of magnesium metabolism
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.696 0.304 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.696 0.304 0.000
B65-B83 Helminthiases
0.696 0.304 0.000
B50-B64 Protozoal diseases
0.696 0.304 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.696 0.304 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.696 0.304 0.000
A75-A79 Rickettsioses
0.696 0.304 0.000
A70-A74 Other diseases caused by chlamydiae
0.696 0.304 0.000
A65-A69 Other spirochaetal diseases
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.696 0.304 0.000
A20-A28 Certain zoonotic bacterial diseases
0.696 0.304 0.000
A15-A19 Tuberculosis
0.696 0.304 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.695 0.305 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.695 0.305 0.000
K82 Other diseases of gallbladder
0.694 0.306 0.000
N84.2 Polyp of vagina
0.693 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
E11.8 With unspecified complications
0.693 0.307 0.000
E11.7 With multiple complications
0.693 0.307 0.000
E11.6 With other specified complications
0.693 0.307 0.000
E11.1 With ketoacidosis
0.693 0.307 0.000
E11.0 With coma
0.693 0.307 0.000
D03 Melanoma in situ
0.692 0.308 0.000
T85.2 Mechanical complication of intraocular lens
0.692 0.308 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.692 0.308 0.000
A30-A49 Other bacterial diseases
0.692 0.308 0.000
J37 Chronic laryngitis and laryngotracheitis
0.691 0.309 0.000
K76.9 Liver disease, unspecified
0.691 0.309 0.000
E20-E35 Disorders of other endocrine glands
0.691 0.309 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.691 0.309 0.000
Z82.3 Family history of stroke
0.689 0.311 0.000
I30 Acute pericarditis
0.689 0.311 0.000
E65-E68 Obesity and other hyperalimentation
0.689 0.311 0.000
J39 Other diseases of upper respiratory tract
0.688 0.312 0.000
N71 Inflammatory disease of uterus, except cervix
0.688 0.312 0.000
J60-J70 Lung diseases due to external agents
0.687 0.313 0.000
C78.7 Secondary malignant neoplasm of liver
0.687 0.313 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.686 0.313 0.000
J90-J94 Other diseases of pleura
0.686 0.314 0.000
Y85 Sequelae of transport accidents
0.684 0.315 0.000
N98 Complications associated with artificial fertilisation
0.684 0.316 0.000
N91 Absent, scanty and rare menstruation
0.684 0.316 0.000
N82 Fistulae involving female genital tract
0.684 0.316 0.000
N96 Habitual aborter
0.684 0.316 0.000
C77.3 Axillary and upper limb lymph nodes
0.684 0.316 0.000
N30.8 Other cystitis
0.683 0.317 0.000
N84.9 Polyp of female genital tract, unspecified
0.683 0.317 0.000
N84.8 Polyp of other parts of female genital tract
0.683 0.317 0.000
N84.3 Polyp of vulva
0.683 0.317 0.000
I31.9 Disease of pericardium, unspecified
0.683 0.317 0.000
E11.2 With renal complications
0.682 0.318 0.000
I95.9 Hypotension, unspecified
0.682 0.318 0.000
I52 Other heart disorders in diseases classified elsewhere
0.682 0.318 0.000
I48 Atrial fibrillation and flutter
0.682 0.318 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.682 0.318 0.000
I41 Myocarditis in diseases classified elsewhere
0.682 0.318 0.000
I40 Acute myocarditis
0.682 0.318 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.682 0.318 0.000
I37 Pulmonary valve disorders
0.682 0.318 0.000
I36 Nonrheumatic tricuspid valve disorders
0.682 0.318 0.000
I33 Acute and subacute endocarditis
0.682 0.318 0.000
I32 Pericarditis in diseases classified elsewhere
0.682 0.318 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.682 0.318 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.682 0.318 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.682 0.318 0.000
D46 Myelodysplastic syndromes
0.682 0.318 0.000
O60-O75 Complications of labour and delivery
0.681 0.319 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.681 0.319 0.000
C34.9 Bronchus or lung, unspecified
0.680 0.320 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.320 0.000
J33.1 Polypoid sinus degeneration
0.680 0.320 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.680 0.320 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.680 0.320 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.680 0.320 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.680 0.320 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.680 0.320 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.680 0.320 0.000
T93 Sequelae of injuries of lower limb
0.679 0.320 0.000
K86.9 Disease of pancreas, unspecified
0.679 0.321 0.000
I45 Other conduction disorders
0.679 0.321 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.678 0.322 0.000
D47.1 Chronic myeloproliferative disease
0.678 0.322 0.000
Z87 Personal history of other diseases and conditions
0.678 0.322 0.000
X60-X84 Intentional self-harm
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.323 0.000
Z97 Presence of other devices
0.676 0.323 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.676 0.323 0.000
Y42.7 Androgens and anabolic congeners
0.676 0.324 0.000
D06 Carcinoma in situ of cervix uteri
0.676 0.324 0.000
O04 Medical abortion
0.675 0.325 0.000
I27 Other pulmonary heart diseases
0.675 0.325 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.675 0.325 0.000
I60-I69 Cerebrovascular diseases
0.674 0.326 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.674 0.326 0.000
Z93.9 Artificial opening status, unspecified
0.673 0.326 0.000
Z93.8 Other artificial opening status
0.673 0.326 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.673 0.326 0.000
Z93.0 Tracheostomy status
0.673 0.326 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.673 0.327 0.000
V20-V29 Motorcycle rider injured in transport accident
0.672 0.328 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.672 0.328 0.000
Z89.6 Acquired absence of leg above knee
0.671 0.329 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.671 0.329 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.671 0.329 0.000
D45 Polycythaemia vera
0.671 0.329 0.000
K00 Disorders of tooth development and eruption
0.670 0.330 0.000
I85 Oesophageal varices
0.670 0.330 0.000
H35.6 Retinal haemorrhage
0.669 0.331 0.000
I42.0 Dilated cardiomyopathy
0.669 0.331 0.000
K66.0 Peritoneal adhesions
0.669 0.331 0.000
Z34.0 Supervision of normal first pregnancy
0.669 0.331 0.000
Z83.3 Family history of diabetes mellitus
0.669 0.331 0.000
C25.0 Head of pancreas
0.669 0.331 0.000
B25-B34 Other viral diseases
0.668 0.332 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
H34 Retinal vascular occlusions
0.668 0.332 0.000
K70.3 Alcoholic cirrhosis of liver
0.667 0.333 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.667 0.333 0.000
I50 Heart failure
0.667 0.333 0.000
C16 Malignant neoplasm of stomach
0.666 0.334 0.000
H43-H45 Disorders of vitreous body and globe
0.666 0.334 0.000
I47 Paroxysmal tachycardia
0.666 0.334 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.665 0.334 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.665 0.334 0.000
J36 Peritonsillar abscess
0.664 0.335 0.000
C77.8 Lymph nodes of multiple regions
0.665 0.335 0.000
E10.8 With unspecified complications
0.664 0.336 0.000
E10.7 With multiple complications
0.664 0.336 0.000
E10.6 With other specified complications
0.664 0.336 0.000
E10.5 With peripheral circulatory complications
0.664 0.336 0.000
E10.2 With renal complications
0.664 0.336 0.000
E10.0 With coma
0.664 0.336 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.664 0.336 0.000
Z83.6 Family history of diseases of the respiratory system
0.663 0.337 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.663 0.337 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.663 0.337 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.663 0.337 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.663 0.337 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
Z93.6 Other artificial openings of urinary tract status
0.662 0.338 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.662 0.338 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.661 0.339 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.661 0.339 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.661 0.339 0.000
T82.3 Mechanical complication of other vascular grafts
0.661 0.339 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.661 0.339 0.000
E83.1 Disorders of iron metabolism
0.661 0.339 0.000
E88 Other metabolic disorders
0.660 0.339 0.000
Y44 Agents primarily affecting blood constituents
0.660 0.340 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.659 0.341 0.000
N92 Excessive, frequent and irregular menstruation
0.659 0.341 0.000
K90-K93 Other diseases of the digestive system
0.659 0.341 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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