TreeWAS – Variant ID: rs7914606

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N21.0 Calculus in bladder	0.022	0.978	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.017	0.983	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.017	0.983	0.000
K80 Cholelithiasis	0.016	0.984	0.000
K80.8 Other cholelithiasis	0.013	0.987	0.000
K80.4 Calculus of bile duct with cholecystitis	0.013	0.987	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.012	0.988	0.000
K80.3 Calculus of bile duct with cholangitis	0.011	0.989	0.000
N21 Calculus of lower urinary tract	0.011	0.989	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.991	0.009
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.008	0.992	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.992	0.008
O80.0 Spontaneous vertex delivery	0.008	0.992	0.000
N21.1 Calculus in urethra	0.008	0.992	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.008	0.992	0.000
N21.8 Other lower urinary tract calculus	0.008	0.992	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.993	0.007
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.993	0.007
R04.2 Haemoptysis	0.000	0.994	0.006
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.000	0.994	0.006
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.994	0.006
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.995	0.005
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.995	0.005
Z98.0 Intestinal bypass and anastomosis status	0.000	0.995	0.005
Z98.1 Arthrodesis status	0.000	0.995	0.005
R39.1 Other difficulties with micturition	0.000	0.995	0.005
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.995	0.005
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.995	0.005
A08.4 Viral intestinal infection, unspecified	0.000	0.996	0.004
R35 Polyuria	0.000	0.996	0.004
Z98 Other postsurgical states	0.000	0.996	0.004
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.996	0.004
K20 Oesophagitis	0.000	0.996	0.004
K40 Inguinal hernia	0.000	0.996	0.004
I51.8 Other ill-defined heart diseases	0.000	0.996	0.004
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
O80 Single spontaneous delivery	0.003	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.997	0.003
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.997	0.003
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.997	0.003
M79.00 Rheumatism, unspecified (Multiple sites)	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.997	0.003
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.997	0.003
T78.3 Angioneurotic oedema	0.003	0.997	0.000
I51.7 Cardiomegaly	0.000	0.997	0.003
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
K43 Ventral hernia	0.000	0.997	0.003
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.997	0.003
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.997	0.003
I51 Complications and ill-defined descriptions of heart disease	0.000	0.997	0.003
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.997	0.003
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.997	0.003
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.997	0.003
K80.1 Calculus of gallbladder with other cholecystitis	0.003	0.997	0.000
R04 Haemorrhage from respiratory passages	0.000	0.997	0.003
O80.8 Other single spontaneous delivery	0.003	0.997	0.000
O80.1 Spontaneous breech delivery	0.003	0.997	0.000
Z98.8 Other specified postsurgical states	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
K46 Unspecified abdominal hernia	0.000	0.997	0.003
E29 Testicular dysfunction	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.000	0.997	0.003
A41.9 Septicaemia, unspecified	0.000	0.997	0.003
I33.0 Acute and subacute infective endocarditis	0.000	0.997	0.003
I51.9 Heart disease, unspecified	0.000	0.997	0.003
S06 Intracranial injury	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
K40-K46 Hernia	0.000	0.997	0.003
G51.0 Bell's palsy	0.000	0.997	0.003
S06.2 Diffuse brain injury	0.002	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.998	0.002
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.998	0.002
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.998	0.002
K43.4 Parastomal hernia with gangrene	0.000	0.998	0.002
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.998	0.002
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.998	0.002
K43.1 Ventral hernia with gangrene	0.000	0.998	0.002
I51.6 Cardiovascular disease, unspecified	0.000	0.998	0.002
R07.3 Other chest pain	0.000	0.998	0.002
I51.5 Myocardial degeneration	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.002	0.998	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.998	0.002
R04.1 Haemorrhage from throat	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.002	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
N20-N23 Urolithiasis	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.000	0.998	0.002
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
N28.1 Cyst of kidney, acquired	0.000	0.998	0.002
O02.1 Missed abortion	0.000	0.998	0.002
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
I50 Heart failure	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
R01 Cardiac murmurs and other cardiac sounds	0.000	0.998	0.002
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.002	0.998	0.000
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
R39 Other symptoms and signs involving the urinary system	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.002	0.998	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
K41 Femoral hernia	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
I50.0 Congestive heart failure	0.000	0.998	0.002
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
S66.8 Injury of other muscles and tendons at wrist and hand level	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.998	0.002
S06.3 Focal brain injury	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
I30-I52 Other forms of heart disease	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.998	0.002
R09.1 Pleurisy	0.000	0.998	0.002
R26.0 Ataxic gait	0.000	0.998	0.002
K45 Other abdominal hernia	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
R01.0 Benign and innocent cardiac murmurs	0.000	0.998	0.002
N22 Calculus of urinary tract in diseases classified elsewhere	0.002	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.002
R26.3 Immobility	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
R26.1 Paralytic gait	0.000	0.998	0.002
E26 Hyperaldosteronism	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
R01.2 Other cardiac sounds	0.000	0.998	0.002
E34 Other endocrine disorders	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
C43.5 Malignant melanoma of trunk	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.002	0.998	0.000
R39.2 Extrarenal uraemia	0.000	0.998	0.002
R39.0 Extravasation of urine	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
I49 Other cardiac arrhythmias	0.000	0.998	0.002
C43.2 Malignant melanoma of ear and external auricular canal	0.002	0.998	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.998	0.002
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.998	0.002
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.998	0.002
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.998	0.002
R09.3 Abnormal sputum	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
T78.9 Adverse effect, unspecified	0.002	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.000	0.998	0.002
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.001
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.002
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.998	0.000
A08 Viral and other specified intestinal infections	0.000	0.998	0.002
I52 Other heart disorders in diseases classified elsewhere	0.000	0.998	0.002
I48 Atrial fibrillation and flutter	0.000	0.998	0.002
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.998	0.002
I41 Myocarditis in diseases classified elsewhere	0.000	0.998	0.002
I40 Acute myocarditis	0.000	0.998	0.002
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I32 Pericarditis in diseases classified elsewhere	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
K45.1 Other specified abdominal hernia with gangrene	0.000	0.998	0.001
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.998	0.001
L91.0 Keloid scar	0.002	0.998	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.001	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.001	0.998	0.000
C43 Malignant melanoma of skin	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.000	0.998	0.002
C43.9 Malignant melanoma of skin, unspecified	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.001	0.998	0.000
E24.8 Other Cushing's syndrome	0.001	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.001	0.998	0.000
E24.1 Nelson's syndrome	0.001	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.998	0.000
E25.8 Other adrenogenital disorders	0.001	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.998	0.000
E30.8 Other disorders of puberty	0.001	0.998	0.000
E30.1 Precocious puberty	0.001	0.998	0.000
E30.0 Delayed puberty	0.001	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.998	0.000
E31.8 Other polyglandular dysfunction	0.001	0.998	0.000
E31.1 Polyglandular hyperfunction	0.001	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.998	0.000
E32.9 Disease of thymus, unspecified	0.001	0.998	0.000
E32.8 Other diseases of thymus	0.001	0.998	0.000
E32.1 Abscess of thymus	0.001	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.001	0.998	0.000
E23.6 Other disorders of pituitary gland	0.001	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.001	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.001	0.998	0.000
E34.8 Other specified endocrine disorders	0.001	0.998	0.000
E34.5 Androgen resistance syndrome	0.001	0.998	0.000
E34.4 Constitutional tall stature	0.001	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
R06.2 Wheezing	0.000	0.998	0.002
E28 Ovarian dysfunction	0.001	0.998	0.000
I42 Cardiomyopathy	0.000	0.998	0.002
I30 Acute pericarditis	0.000	0.998	0.001
R07 Pain in throat and chest	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.001	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.001	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.001	0.998	0.000
E27.2 Addisonian crisis	0.001	0.998	0.000
E27.0 Other adrenocortical overactivity	0.001	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
K44 Diaphragmatic hernia	0.000	0.998	0.002
H02.3 Blepharochalasis	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.001
N20 Calculus of kidney and ureter	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.001	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.001
I37 Pulmonary valve disorders	0.000	0.998	0.001
A63.0 Anogenital (venereal) warts	0.000	0.998	0.001
I49.2 Junctional premature depolarisation	0.000	0.998	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.001	0.998	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.998	0.001
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.998	0.001
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.998	0.001
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.998	0.001
N60.2 Fibroadenosis of breast	0.001	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.001	0.998	0.000
G25.0 Essential tremor	0.001	0.998	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.001	0.998	0.000
D18 Haemangioma and lymphangioma, any site	0.001	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
A08.5 Other specified intestinal infections	0.000	0.999	0.001
A08.3 Other viral enteritis	0.000	0.999	0.001
A08.2 Adenoviral enteritis	0.000	0.999	0.001
A08.0 Rotaviral enteritis	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.999	0.001
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.999	0.001
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.999	0.001
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.999	0.001
I40.9 Acute myocarditis, unspecified	0.000	0.999	0.001
I40.8 Other acute myocarditis	0.000	0.999	0.001
I40.1 Isolated myocarditis	0.000	0.999	0.001
I40.0 Infective myocarditis	0.000	0.999	0.001
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.999	0.001
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.999	0.001
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.999	0.001
I42.2 Other hypertrophic cardiomyopathy	0.000	0.999	0.001
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.999	0.001
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.999	0.001
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.999	0.001
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I44.7 Left bundle-branch block, unspecified	0.000	0.999	0.001
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.999	0.001
I48.4 Atypical atrial flutter	0.000	0.999	0.001
I48.3 Typical atrial flutter	0.000	0.999	0.001
I48.2 Chronic atrial fibrillation	0.000	0.999	0.001
I48.1 Persistent atrial fibrillation	0.000	0.999	0.001
I48.0 Paroxysmal atrial fibrillation	0.000	0.999	0.001
I49.1 Atrial premature depolarisation	0.000	0.999	0.001
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.999	0.001
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.999	0.001
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
C43.8 Overlapping malignant melanoma of skin	0.001	0.999	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.001	0.999	0.000
C43.0 Malignant melanoma of lip	0.001	0.999	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.999	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
I30.8 Other forms of acute pericarditis	0.000	0.999	0.001
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.999	0.001
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.999	0.001
I42.6 Alcoholic cardiomyopathy	0.000	0.999	0.001
I42.5 Other restrictive cardiomyopathy	0.000	0.999	0.001
I42.4 Endocardial fibroelastosis	0.000	0.999	0.001
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.999	0.001
I44.6 Other and unspecified fascicular block	0.000	0.999	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.001	0.999	0.000
J33.0 Polyp of nasal cavity	0.000	0.999	0.001
K44.1 Diaphragmatic hernia with gangrene	0.000	0.999	0.001
R07.1 Chest pain on breathing	0.000	0.999	0.001
I46 Cardiac arrest	0.000	0.999	0.001
R02 Gangrene, not elsewhere classified	0.000	0.999	0.001
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
I30.1 Infective pericarditis	0.000	0.999	0.001
I37.9 Pulmonary valve disorder, unspecified	0.000	0.999	0.001
I37.8 Other pulmonary valve disorders	0.000	0.999	0.001
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.999	0.001
I37.0 Pulmonary valve stenosis	0.000	0.999	0.001
I42.9 Cardiomyopathy, unspecified	0.000	0.999	0.001
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
T70.3 Caisson disease [decompression sickness]	0.001	0.999	0.000
K42 Umbilical hernia	0.000	0.999	0.001
I44.5 Left posterior fascicular block	0.000	0.999	0.001
I44.4 Left anterior fascicular block	0.000	0.999	0.001
I49.4 Other and unspecified premature depolarisation	0.000	0.999	0.001
L82 Seborrhoeic keratosis	0.001	0.999	0.000
R00 Abnormalities of heart beat	0.000	0.999	0.001
B37.3 Candidiasis of vulva and vagina	0.001	0.999	0.000
D18.1 Lymphangioma, any site	0.001	0.999	0.000
E23.0 Hypopituitarism	0.001	0.999	0.000
K82.9 Disease of gallbladder, unspecified	0.001	0.999	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.999	0.001
O80-O84 Delivery	0.001	0.999	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.999	0.001
I44.3 Other and unspecified atrioventricular block	0.000	0.999	0.001
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.999	0.001
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I31 Other diseases of pericardium	0.000	0.999	0.001
M77.12 Lateral epicondylitis (Upper arm)	0.001	0.999	0.000
I42.8 Other cardiomyopathies	0.000	0.999	0.001
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.999	0.001
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
K82.4 Cholesterolosis of gallbladder	0.001	0.999	0.000
K82 Other diseases of gallbladder	0.001	0.999	0.000
T70 Effects of air pressure and water pressure	0.001	0.999	0.000
G12.2 Motor neuron disease	0.001	0.999	0.000
M31.6 Other giant cell arteritis	0.000	0.999	0.001
I45 Other conduction disorders	0.000	0.999	0.001
I42.0 Dilated cardiomyopathy	0.000	0.999	0.001
I50.1 Left ventricular failure	0.000	0.999	0.001
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.999	0.001
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.001	0.999	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
S82.20 Fracture of shaft of tibia (closed)	0.001	0.999	0.000
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
M77.02 Medial epicondylitis (Upper arm)	0.001	0.999	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.999	0.001
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.999	0.001
T51.0 Ethanol	0.001	0.999	0.000
T66-T78 Other and unspecified effects of external causes	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
K85.9 Acute pancreatitis, unspecified	0.001	0.999	0.000
O84 Multiple delivery	0.001	0.999	0.000
O83 Other assisted single delivery	0.001	0.999	0.000
T75 Effects of other external causes	0.001	0.999	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.999	0.001
I31.8 Other specified diseases of pericardium	0.000	0.999	0.001
I31.2 Haemopericardium, not elsewhere classified	0.000	0.999	0.001
I31.1 Chronic constrictive pericarditis	0.000	0.999	0.001
I31.0 Chronic adhesive pericarditis	0.000	0.999	0.001
K82.3 Fistula of gallbladder	0.001	0.999	0.000
K82.0 Obstruction of gallbladder	0.001	0.999	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.001	0.999	0.000
T70.8 Other effects of air pressure and water pressure	0.001	0.999	0.000
T70.4 Effects of high-pressure fluids	0.001	0.999	0.000
T70.2 Other and unspecified effects of high altitude	0.001	0.999	0.000
T70.1 Sinus barotrauma	0.001	0.999	0.000
T70.0 Otitic barotrauma	0.001	0.999	0.000
I45.4 Nonspecific intraventricular block	0.000	0.999	0.001
I45.0 Right fascicular block	0.000	0.999	0.001
K08.9 Disorder of teeth and supporting structures, unspecified	0.001	0.999	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.999	0.001
R00.2 Palpitations	0.000	0.999	0.001
T75.4 Effects of electric current	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
C43.4 Malignant melanoma of scalp and neck	0.001	0.999	0.000
C71.9 Brain, unspecified	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
K87.1 Disorders of pancreas in diseases classified elsewhere	0.001	0.999	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.001	0.999	0.000
S42.2 Fracture of upper end of humerus	0.001	0.999	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.999	0.001
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
K85 Acute pancreatitis	0.001	0.999	0.000
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
H18.9 Disorder of cornea, unspecified	0.001	0.999	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.999	0.001
K82.2 Perforation of gallbladder	0.001	0.999	0.000
R07.0 Pain in throat	0.000	0.999	0.001
O02 Other abnormal products of conception	0.000	0.999	0.001
O81 Single delivery by forceps and vacuum extractor	0.001	0.999	0.000
T74 Maltreatment syndromes	0.001	0.999	0.000
T73 Effects of other deprivation	0.001	0.999	0.000
T69 Other effects of reduced temperature	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations