TreeWAS – Variant ID: rs7915137

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H35.8 Other specified retinal disorders	0.000	0.598	0.402
I35.1 Aortic (valve) insufficiency	0.000	0.667	0.333
I35 Nonrheumatic aortic valve disorders	0.000	0.844	0.156
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.854	0.146
I35.8 Other aortic valve disorders	0.000	0.869	0.131
H35 Other retinal disorders	0.000	0.873	0.127
Z80.3 Family history of malignant neoplasm of breast	0.000	0.886	0.114
Z80 Family history of malignant neoplasm	0.000	0.888	0.112
H35.4 Peripheral retinal degeneration	0.000	0.890	0.110
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.891	0.109
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.892	0.108
H35.9 Retinal disorder, unspecified	0.000	0.893	0.106
H35.7 Separation of retinal layers	0.000	0.896	0.104
H35.5 Hereditary retinal dystrophy	0.000	0.896	0.104
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.898	0.102
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.901	0.099
Z80.6 Family history of leukaemia	0.000	0.905	0.095
H35.1 Retinopathy of prematurity	0.000	0.909	0.091
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.917	0.083
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.928	0.072
I35.9 Aortic valve disorder, unspecified	0.000	0.930	0.070
H35.2 Other proliferative retinopathy	0.000	0.932	0.068
H35.6 Retinal haemorrhage	0.000	0.936	0.064
H35.0 Background retinopathy and retinal vascular changes	0.000	0.957	0.043
H35.3 Degeneration of macula and posterior pole	0.000	0.968	0.032
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.969	0.031
S82.10 Fracture of upper end of tibia (closed)	0.030	0.970	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.027	0.973	0.000
H30-H36 Disorders of choroid and retina	0.000	0.974	0.026
I35.0 Aortic (valve) stenosis	0.000	0.978	0.022
H31 Other disorders of choroid	0.000	0.979	0.021
H30 Chorioretinal inflammation	0.000	0.981	0.019
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.981	0.019
H31.1 Choroidal degeneration	0.000	0.982	0.018
H34 Retinal vascular occlusions	0.000	0.982	0.017
H31.0 Chorioretinal scars	0.000	0.984	0.016
H31.3 Choroidal haemorrhage and rupture	0.000	0.984	0.016
H31.9 Disorder of choroid, unspecified	0.000	0.984	0.015
H31.4 Choroidal detachment	0.000	0.984	0.015
H31.2 Hereditary choroidal dystrophy	0.000	0.984	0.015
R10.2 Pelvic and perineal pain	0.015	0.985	0.000
H34.2 Other retinal artery occlusions	0.000	0.985	0.014
H31.8 Other specified disorders of choroid	0.000	0.986	0.014
H30.9 Chorioretinal inflammation, unspecified	0.000	0.986	0.014
K25.3 Acute without haemorrhage or perforation	0.014	0.986	0.000
H30.8 Other chorioretinal inflammations	0.000	0.986	0.014
H30.2 Posterior cyclitis	0.000	0.986	0.014
H30.1 Disseminated chorioretinal inflammation	0.000	0.986	0.014
H30.0 Focal chorioretinal inflammation	0.000	0.986	0.014
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.986	0.014
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.986	0.014
H33 Retinal detachments and breaks	0.000	0.986	0.014
H34.1 Central retinal artery occlusion	0.000	0.987	0.013
H34.0 Transient retinal artery occlusion	0.000	0.987	0.013
H33.1 Retinoschisis and retinal cysts	0.000	0.988	0.012
H33.4 Traction detachment of retina	0.000	0.988	0.012
H36 Retinal disorders in diseases classified elsewhere	0.000	0.988	0.012
H34.9 Retinal vascular occlusion, unspecified	0.000	0.989	0.011
S82.1 Fracture of upper end of tibia	0.010	0.990	0.000
H33.2 Serous retinal detachment	0.000	0.990	0.010
H34.8 Other retinal vascular occlusions	0.000	0.990	0.010
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.990	0.010
H33.0 Retinal detachment with retinal break	0.000	0.990	0.010
E21.3 Hyperparathyroidism, unspecified	0.009	0.991	0.000
E21.0 Primary hyperparathyroidism	0.009	0.991	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.991	0.008
T88.5 Other complications of anaesthesia	0.008	0.992	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.992	0.008
K55.2 Angiodysplasia of colon	0.000	0.993	0.007
R60.9 Oedema, unspecified	0.000	0.993	0.007
E21.5 Disorder of parathyroid gland, unspecified	0.007	0.993	0.000
K55 Vascular disorders of intestine	0.000	0.993	0.007
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.007	0.993	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.007	0.993	0.000
C92.0 Acute myeloid leukaemia	0.000	0.993	0.007
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
S82.11 Fracture of upper end of tibia (open)	0.006	0.993	0.000
E21.2 Other hyperparathyroidism	0.006	0.994	0.000
K55.8 Other vascular disorders of intestine	0.000	0.994	0.006
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.006	0.994	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.994	0.006
C92.1 Chronic myeloid leukaemia	0.000	0.994	0.006
K55.1 Chronic vascular disorders of intestine	0.000	0.994	0.006
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.005	0.995	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.995	0.005
C92 Myeloid leukaemia	0.000	0.995	0.005
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.005	0.995	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
T93.2 Sequelae of other fractures of lower limb	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.000	0.996	0.004
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.996	0.004
K25.7 Chronic without haemorrhage or perforation	0.004	0.996	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.996	0.004
C92.9 Myeloid leukaemia, unspecified	0.000	0.996	0.004
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.996	0.004
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.996	0.004
C92.3 Myeloid sarcoma	0.000	0.996	0.004
C92.2 Subacute myeloid leukaemia	0.000	0.996	0.004
T88.3 Malignant hyperthermia due to anaesthesis	0.004	0.996	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.004	0.996	0.000
T88.0 Infection following immunisation	0.004	0.996	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
C92.7 Other myeloid leukaemia	0.000	0.996	0.004
H59.0 Vitreous syndrome following cataract surgery	0.000	0.996	0.004
T88.2 Shock due to anaesthesia	0.004	0.996	0.000
T88.9 Complication of surgical and medical care, unspecified	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
C92.5 Acute myelomonocytic leukaemia	0.000	0.996	0.004
H33.5 Other retinal detachments	0.000	0.996	0.003
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
Z90.3 Acquired absence of part of stomach	0.000	0.996	0.004
Z04.9 Examination and observation for unspecified reason	0.004	0.996	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.003	0.996	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
K80.8 Other cholelithiasis	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
H26.8 Other specified cataract	0.000	0.997	0.003
K25 Gastric ulcer	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
N64.1 Fat necrosis of breast	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
J32.2 Chronic ethmoidal sinusitis	0.003	0.997	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
K25.5 Chronic or unspecified with perforation	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.997	0.000
K25.2 Acute with both haemorrhage and perforation	0.002	0.997	0.000
K25.1 Acute with perforation	0.002	0.997	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.997	0.000
E24.1 Nelson's syndrome	0.002	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.002	0.997	0.000
V28.9 Unspecified motorcycle rider injured in traffic accident	0.002	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.002	0.997	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.003	0.997	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
L50.0 Allergic urticaria	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.002	0.998	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
H26.2 Complicated cataract	0.000	0.998	0.002
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
V28 Motorcycle rider injured in noncollision transport accident	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
V28.5 Passenger injured in traffic accident	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
L50 Urticaria	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
V28.2 Unspecified motorcycle rider injured in nontraffic accident	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N04.9 Unspecified	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
H26 Other cataract	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
H26.0 Infantile, juvenile and presenile cataract	0.000	0.998	0.002
T88.4 Failed or difficult intubation	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.998	0.002
T39.0 Salicylates	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.998	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
H52.0 Hypermetropia	0.000	0.998	0.002
L50.8 Other urticaria	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
V28.4 Driver injured in traffic accident	0.002	0.998	0.000
V28.0 Driver injured in nontraffic accident	0.002	0.998	0.000
V28.3 Person injured while boarding or alighting	0.002	0.998	0.000
V28.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
K25.0 Acute with haemorrhage	0.001	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
H52.2 Astigmatism	0.000	0.998	0.002
H26.1 Traumatic cataract	0.000	0.998	0.002
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
J47 Bronchiectasis	0.000	0.998	0.002
Z40.8 Other prophylactic surgery	0.000	0.998	0.002
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
H26.3 Drug-induced cataract	0.000	0.998	0.002
E28 Ovarian dysfunction	0.001	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.001	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
N34.2 Other urethritis	0.000	0.998	0.002
V28.09 Motorcycle rider injured in noncollision transport accident; driver injured in nontraffic accident; during unspecified activity	0.001	0.998	0.000
V28.49 Motorcycle rider injured in noncollision transport accident; driver injured in traffic accident; during unspecified activity	0.001	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
F06.7 Mild cognitive disorder	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.998	0.000
Y46.4 Iminostilbenes	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.001	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.001
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.998	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.998	0.000
H52.6 Other disorders of refraction	0.000	0.998	0.001
H52.5 Disorders of accommodation	0.000	0.998	0.001
H52.4 Presbyopia	0.000	0.998	0.001
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.001
E27.4 Other and unspecified adrenocortical insufficiency	0.001	0.999	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.001	0.999	0.000
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.001	0.999	0.000
H47.1 Papilloedema, unspecified	0.000	0.999	0.001
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
Z71.9 Counselling, unspecified	0.000	0.999	0.001
B16 Acute hepatitis B	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.999	0.001
I61.8 Other intracerebral haemorrhage	0.000	0.999	0.001
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
E11.1 With ketoacidosis	0.000	0.999	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.999	0.001
D37.4 Colon	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.001	0.999	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.999	0.001
E27.8 Other specified disorders of adrenal gland	0.001	0.999	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.999	0.001
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.999	0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.999	0.001
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.999	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.999	0.001
M87.9 Osteonecrosis, unspecified	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
R26.0 Ataxic gait	0.000	0.999	0.001
Y00.9 Unspecified place	0.000	0.999	0.001
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.001	0.999	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.001	0.999	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.001	0.999	0.000
T93.0 Sequelae of open wound of lower limb	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.001	0.999	0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
T44.0 Anticholinesterase agents	0.001	0.999	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
K25.4 Chronic or unspecified with haemorrhage	0.001	0.999	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.999	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.001	0.999	0.000
D37.9 Digestive organ, unspecified	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.001	0.999	0.000
H26.4 After-cataract	0.000	0.999	0.001
H57.0 Anomalies of pupillary function	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
S50.8 Other superficial injuries of forearm	0.000	0.999	0.001
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
D04.5 Skin of trunk	0.001	0.999	0.000
D37.2 Small intestine	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.999	0.001
N05.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.999	0.000
T39.4 Antirheumatics, not elsewhere classified	0.001	0.999	0.000
T39.2 Pyrazolone derivatives	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.001	0.999	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.999	0.001
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.999	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.999	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.999	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.999	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.999	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.999	0.001
O86.8 Other specified puerperal infections	0.001	0.999	0.000
W06.0 Home	0.001	0.999	0.000
M71.34 Other bursal cyst (Hand)	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.999	0.001
V04.1 Traffic accident	0.000	0.999	0.001
V49.8 Car occupant [any] injured in other specified transport accidents	0.001	0.999	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.001	0.999	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.001	0.999	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.999	0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
D43.9 Central nervous system, unspecified	0.001	0.999	0.000
D43.7 Other parts of central nervous system	0.001	0.999	0.000
D43.3 Cranial nerves	0.001	0.999	0.000
D43.1 Brain, infratentorial	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.001	0.999	0.001
M24.24 Disorder of ligament (Hand)	0.001	0.999	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.999	0.001
L60.8 Other nail disorders	0.001	0.999	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.999	0.001
D44.9 Endocrine gland, unspecified	0.001	0.999	0.000
E23.0 Hypopituitarism	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.001	0.999	0.000
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
R90.0 Intracranial space-occupying lesion	0.001	0.999	0.000
Z97.8 Presence of other specified devices	0.001	0.999	0.000
V49.81 Car occupant injured in trnsp accident w military vehicle (Car occupant (driver) (passenger) injured in transport accident with military vehicle)	0.001	0.999	0.000
H47.2 Optic atrophy	0.000	0.999	0.001
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.999	0.001
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.999	0.000
D26.9 Uterus, unspecified	0.001	0.999	0.000
D44.8 Pluriglandular involvement	0.001	0.999	0.000
H57.1 Ocular pain	0.000	0.999	0.001
K72.9 Hepatic failure, unspecified	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.001	0.999	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.001	0.999	0.000
V29.3 Motorcycle rider [any] injured in unspecified nontraffic accident	0.001	0.999	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.001	0.999	0.000
M79.19 Myalgia (Site unspecified)	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
S82.01 Fracture of patella (open)	0.000	0.999	0.001
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.999	0.001
C25.9 Pancreas, unspecified	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.999	0.001
M76.87 Other enthesopathies of lower limb, excluding foot (Ankle and foot)	0.001	0.999	0.000
B18.2 Chronic viral hepatitis C	0.000	0.999	0.001
D44.5 Pineal gland	0.001	0.999	0.000
D44.2 Parathyroid gland	0.001	0.999	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.001	0.999	0.000
L12.1 Cicatricial pemphigoid	0.000	0.999	0.001
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.999	0.001
I61 Intracerebral haemorrhage	0.000	0.999	0.001
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
K70.3 Alcoholic cirrhosis of liver	0.001	0.999	0.000
L12.0 Bullous pemphigoid	0.000	0.999	0.001
R70.0 Elevated erythrocyte sedimentation rate	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
G70.9 Myoneural disorder, unspecified	0.001	0.999	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.999	0.001
H47.6 Disorders of visual cortex	0.000	0.999	0.001
H47.5 Disorders of other visual pathways	0.000	0.999	0.001
H47.4 Disorders of optic chiasm	0.000	0.999	0.001
M19.0 Primary arthrosis of other joints	0.000	0.999	0.001
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.999	0.001
O44.0 Placenta praevia specified as without haemorrhage	0.001	0.999	0.000
R41.3 Other amnesia	0.001	0.999	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.999	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
Z97.3 Presence of spectacles and contact lenses	0.001	0.999	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.999	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.999	0.001
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.999	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.999	0.001
D43.4 Spinal cord	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.999	0.001
T39.1 4-Aminophenol derivatives	0.001	0.999	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.999	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.001	0.999	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.999	0.001
R90 Abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
M79.10 Myalgia (Multiple sites)	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations