TreeWAS – Variant ID: rs7927044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.996	0.004
Chapter VI Diseases of the nervous system	0.983	0.017
Chapter IX Diseases of the circulatory system	0.981	0.019
C60-C63 Malignant neoplasms of male genital organs	0.976	0.024
E10-E14 Diabetes mellitus	0.976	0.024
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.973	0.027
D10-D36 Benign neoplasms	0.972	0.028
Chapter I Certain infectious and parasitic diseases	0.963	0.037
C61 Malignant neoplasm of prostate	0.959	0.041
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.952	0.048
I60-I69 Cerebrovascular diseases	0.948	0.052
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.944	0.056
C50-C50 Malignant neoplasm of breast	0.942	0.058
Chapter XV Pregnancy, childbirth and the puerperium	0.942	0.058
A00-A09 Intestinal infectious diseases	0.941	0.059
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.939	0.061
E11 Non-insulin-dependent diabetes mellitus	0.935	0.065
Chapter XX External causes of morbidity and mortality	0.932	0.068
G40-G47 Episodic and paroxysmal disorders	0.921	0.079
C43-C44 Melanoma and other malignant neoplasms of skin	0.915	0.085
G80-G83 Cerebral palsy and other paralytic syndromes	0.913	0.087
M45-M49 Spondylopathies	0.911	0.089
E11.9 Without complications	0.907	0.093
E70-E90 Metabolic disorders	0.906	0.094
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.905	0.095
C50 Malignant neoplasm of breast	0.901	0.099
C79 Secondary malignant neoplasm of other sites	0.899	0.101
Chapter XIV Diseases of the genitourinary system	0.892	0.108
I20-I25 Ischaemic heart diseases	0.886	0.114
I10-I15 Hypertensive diseases	0.880	0.120
E14 Unspecified diabetes mellitus	0.879	0.121
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.875	0.125
E87 Other disorders of fluid, electrolyte and acid-base balance	0.871	0.129
D12.0 Caecum	0.868	0.132
G81 Hemiplegia	0.863	0.137
M20-M25 Other joint disorders	0.862	0.138
M80-M85 Disorders of bone density and structure	0.860	0.139
D22 Melanocytic naevi	0.855	0.145
E00-E07 Disorders of thyroid gland	0.845	0.155
S80-S89 Injuries to the knee and lower leg	0.835	0.165
M47 Spondylosis	0.834	0.166
D12.2 Ascending colon	0.832	0.168
A04 Other bacterial intestinal infections	0.831	0.169
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.829	0.171
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.829	0.171
A09.9 Gastroenteritis and colitis of unspecified origin	0.828	0.172
Chapter VII Diseases of the eye and adnexa	0.828	0.172
G81.9 Hemiplegia, unspecified	0.827	0.173
Chapter VIII Diseases of the ear and mastoid process	0.827	0.173
Chapter V Mental and behavioural disorders	0.819	0.181
I63 Cerebral infarction	0.819	0.181
N60-N64 Disorders of breast	0.817	0.183
E87.6 Hypokalaemia	0.817	0.183
G47 Sleep disorders	0.816	0.184
C44 Other malignant neoplasms of skin	0.816	0.184
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.814	0.186
I10 Essential (primary) hypertension	0.810	0.190
N70-N77 Inflammatory diseases of female pelvic organs	0.810	0.190
E14.9 Without complications	0.809	0.191
I20 Angina pectoris	0.807	0.193
N10-N16 Renal tubulo-interstitial diseases	0.807	0.193
M20 Acquired deformities of fingers and toes	0.806	0.194
D12.5 Sigmoid colon	0.804	0.196
I69 Sequelae of cerebrovascular disease	0.802	0.198
B35-B49 Mycoses	0.800	0.200
D18 Haemangioma and lymphangioma, any site	0.796	0.204
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.792	0.208
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.790	0.210
C44.3 Skin of other and unspecified parts of face	0.789	0.211
O00-O08 Pregnancy with abortive outcome	0.788	0.212
G90-G99 Other disorders of the nervous system	0.788	0.212
I70-I79 Diseases of arteries, arterioles and capillaries	0.785	0.215
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.783	0.217
A08 Viral and other specified intestinal infections	0.779	0.221
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.777	0.223
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.775	0.225
I64 Stroke, not specified as haemorrhage or infarction	0.771	0.228
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.771	0.229
D37-D48 Neoplasms of uncertain or unknown behaviour	0.769	0.231
I67 Other cerebrovascular diseases	0.769	0.231
G47.3 Sleep apnoea	0.767	0.233
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.767	0.233
I20.0 Unstable angina	0.766	0.234
D12.8 Rectum	0.766	0.234
D22.6 Melanocytic naevi of upper limb, including shoulder	0.762	0.238
D70-D77 Other diseases of blood and blood-forming organs	0.762	0.238
C50.8 Overlapping lesion of breast	0.761	0.239
C43 Malignant melanoma of skin	0.757	0.243
S40-S49 Injuries to the shoulder and upper arm	0.755	0.245
C79.8 Secondary malignant neoplasm of other specified sites	0.755	0.245
A04.8 Other specified bacterial intestinal infections	0.753	0.247
S82 Fracture of lower leg, including ankle	0.753	0.247
G40 Epilepsy	0.752	0.248
S60-S69 Injuries to the wrist and hand	0.752	0.248
C50.9 Breast, unspecified	0.751	0.249
M65-M68 Disorders of synovium and tendon	0.748	0.252
D23 Other benign neoplasms of skin	0.748	0.252
M20.2 Hallux rigidus	0.747	0.253
E50-E64 Other nutritional deficiencies	0.746	0.254
A30-A49 Other bacterial diseases	0.745	0.254
D00-D09 In situ neoplasms	0.745	0.255
M48 Other spondylopathies	0.744	0.256
C50.4 Upper-outer quadrant of breast	0.744	0.256
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.741	0.259
G30-G32 Other degenerative diseases of the nervous system	0.741	0.259
C50.0 Nipple and areola	0.741	0.259
E87.0 Hyperosmolality and hypernatraemia	0.740	0.259
O20-O29 Other maternal disorders predominantly related to pregnancy	0.740	0.260
I60 Subarachnoid haemorrhage	0.737	0.263
S50-S59 Injuries to the elbow and forearm	0.735	0.265
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.732	0.268
D35 Benign neoplasm of other and unspecified endocrine glands	0.731	0.269
M47.8 Other spondylosis	0.731	0.269
D12.3 Transverse colon	0.728	0.272
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.728	0.272
M81 Osteoporosis without pathological fracture	0.727	0.273
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.726	0.274
O46 Antepartum haemorrhage, not elsewhere classified	0.725	0.275
H30-H36 Disorders of choroid and retina	0.725	0.275
M05-M14 Inflammatory polyarthropathies	0.724	0.276
F40-F48 Neurotic, stress-related and somatoform disorders	0.724	0.276
M40-M43 Deforming dorsopathies	0.721	0.279
I62 Other nontraumatic intracranial haemorrhage	0.720	0.280
Y60-Y69 Misadventures to patients during surgical and medical care	0.718	0.282
E87.5 Hyperkalaemia	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
C15-C26 Malignant neoplasms of digestive organs	0.717	0.283
G20-G26 Extrapyramidal and movement disorders	0.715	0.285
C44.5 Skin of trunk	0.714	0.286
E40-E46 Malnutrition	0.714	0.286
E03 Other hypothyroidism	0.714	0.286
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.713	0.287
T66-T78 Other and unspecified effects of external causes	0.713	0.287
C77.3 Axillary and upper limb lymph nodes	0.711	0.289
M24 Other specific joint derangements	0.709	0.291
D32 Benign neoplasm of meninges	0.709	0.291
O60-O75 Complications of labour and delivery	0.709	0.291
M47.9 Spondylosis, unspecified	0.709	0.291
S20-S29 Injuries to the thorax	0.708	0.292
G45 Transient cerebral ischaemic attacks and related syndromes	0.708	0.292
E20-E35 Disorders of other endocrine glands	0.707	0.293
D22.5 Melanocytic naevi of trunk	0.706	0.294
G70-G73 Diseases of myoneural junction and muscle	0.705	0.295
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.705	0.295
G00-G09 Inflammatory diseases of the central nervous system	0.705	0.295
I22 Subsequent myocardial infarction	0.705	0.295
I05-I09 Chronic rheumatic heart diseases	0.704	0.295
G44 Other headache syndromes	0.704	0.296
I00-I02 Acute rheumatic fever	0.703	0.297
D50-D53 Nutritional anaemias	0.702	0.298
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.702	0.298
N99-N99 Other disorders of the genitourinary system	0.701	0.298
O94-O99 Other obstetric conditions, not elsewhere classified	0.700	0.299
C63 Malignant neoplasm of other and unspecified male genital organs	0.700	0.300
C62 Malignant neoplasm of testis	0.700	0.300
C60 Malignant neoplasm of penis	0.700	0.300
E13 Other specified diabetes mellitus	0.699	0.301
E12 Malnutrition-related diabetes mellitus	0.699	0.301
N64 Other disorders of breast	0.699	0.301
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.698	0.302
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.698	0.302
M91-M94 Chondropathies	0.698	0.302
M86-M90 Other osteopathies	0.698	0.302
M60-M63 Disorders of muscles	0.698	0.302
M00-M03 Infectious arthropathies	0.698	0.302
M15-M19 Arthrosis	0.698	0.302
D36 Benign neoplasm of other and unspecified sites	0.697	0.303
D33 Benign neoplasm of brain and other parts of central nervous system	0.697	0.303
D31 Benign neoplasm of eye and adnexa	0.697	0.303
D30 Benign neoplasm of urinary organs	0.697	0.303
D29 Benign neoplasm of male genital organs	0.697	0.303
D28 Benign neoplasm of other and unspecified female genital organs	0.697	0.303
D26 Other benign neoplasms of uterus	0.697	0.303
D21 Other benign neoplasms of connective and other soft tissue	0.697	0.303
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.697	0.303
D19 Benign neoplasm of mesothelial tissue	0.697	0.303
D16 Benign neoplasm of bone and articular cartilage	0.697	0.303
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.697	0.303
D14 Benign neoplasm of middle ear and respiratory system	0.697	0.303
D10 Benign neoplasm of mouth and pharynx	0.697	0.303
D34 Benign neoplasm of thyroid gland	0.697	0.303
D11 Benign neoplasm of major salivary glands	0.697	0.303
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.697	0.303
E10 Insulin-dependent diabetes mellitus	0.696	0.304
E86 Volume depletion	0.694	0.306
T36-T50 Poisoning by drugs, medicaments and biological substances	0.693	0.307
E83 Disorders of mineral metabolism	0.692	0.308
O80-O84 Delivery	0.692	0.308
B99-B99 Other infectious diseases	0.691	0.309
B90-B94 Sequelae of infectious and parasitic diseases	0.691	0.309
B85-B89 Pediculosis, acariasis and other infestations	0.691	0.309
B65-B83 Helminthiases	0.691	0.309
B50-B64 Protozoal diseases	0.691	0.309
B20-B24 Human immunodeficiency virus [HIV] disease	0.691	0.309
B15-B19 Viral hepatitis	0.691	0.309
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.691	0.309
A80-A89 Viral infections of the central nervous system	0.691	0.309
A75-A79 Rickettsioses	0.691	0.309
A70-A74 Other diseases caused by chlamydiae	0.691	0.309
A65-A69 Other spirochaetal diseases	0.691	0.309
A50-A64 Infections with a predominantly sexual mode of transmission	0.691	0.309
A20-A28 Certain zoonotic bacterial diseases	0.691	0.309
A15-A19 Tuberculosis	0.691	0.309
I21 Acute myocardial infarction	0.683	0.317
I63.9 Cerebral infarction, unspecified	0.683	0.317
B37 Candidiasis	0.683	0.317
T79-T79 Certain early complications of trauma	0.682	0.318
T33-T35 Frostbite	0.682	0.318
T26-T28 Burns and corrosions confined to eye and internal organs	0.682	0.318
T20-T25 Burns and corrosions of external body surface, specified by site	0.682	0.318
T15-T19 Effects of foreign body entering through natural orifice	0.682	0.318
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.682	0.318
T00-T07 Injuries involving multiple body regions	0.682	0.318
S90-S99 Injuries to the ankle and foot	0.682	0.318
S10-S19 Injuries to the neck	0.682	0.318
N73 Other female pelvic inflammatory diseases	0.682	0.318
N00-N08 Glomerular diseases	0.682	0.318
V10-V19 Pedal cyclist injured in transport accident	0.682	0.318
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.681	0.319
M84 Disorders of continuity of bone	0.681	0.319
D60-D64 Aplastic and other anaemias	0.680	0.320
D17 Benign lipomatous neoplasm	0.680	0.320
I68 Cerebrovascular disorders in diseases classified elsewhere	0.679	0.320
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.679	0.320
I61 Intracerebral haemorrhage	0.679	0.320
G35-G37 Demyelinating diseases of the central nervous system	0.679	0.321
M46 Other inflammatory spondylopathies	0.678	0.321
C80 Malignant neoplasm without specification of site	0.676	0.323
C76 Malignant neoplasm of other and ill-defined sites	0.676	0.323
O85-O92 Complications predominantly related to the puerperium	0.675	0.325
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.675	0.325
A07 Other protozoal intestinal diseases	0.674	0.325
A06 Amoebiasis	0.674	0.325
A05 Other bacterial foodborne intoxications	0.674	0.325
A03 Shigellosis	0.674	0.325
A02 Other Salmonella infections	0.674	0.325
A01 Typhoid and paratyphoid fevers	0.674	0.325
A00 Cholera	0.674	0.325
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.674	0.326
D12.9 Anus and anal canal	0.673	0.327
D12.7 Rectosigmoid junction	0.673	0.327
D12.1 Appendix	0.673	0.327
H40-H42 Glaucoma	0.672	0.328
N17-N19 Renal failure	0.672	0.328
G43 Migraine	0.671	0.328
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.671	0.329
E11.8 With unspecified complications	0.670	0.329
E11.7 With multiple complications	0.670	0.329
E11.6 With other specified complications	0.670	0.329
E11.5 With peripheral circulatory complications	0.670	0.329
E11.2 With renal complications	0.670	0.329
E11.1 With ketoacidosis	0.670	0.329
E11.0 With coma	0.670	0.329
D18.0 Haemangioma, any site	0.670	0.330
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.668	0.331
Y35-Y36 Legal intervention and operations of war	0.668	0.331
Y10-Y34 Event of undetermined intent	0.668	0.331
Y00-Y09 Assault	0.668	0.331
X85-X99 Assault	0.668	0.331
X60-X84 Intentional self-harm	0.668	0.331
X58-X59 Accidental exposure to other and unspecified factors	0.668	0.331
X50-X57 Overexertion, travel and privation	0.668	0.331
X40-X49 Accidental poisoning by and exposure to noxious substances	0.668	0.331
X30-X39 Exposure to forces of nature	0.668	0.331
X20-X29 Contact with venomous animals and plants	0.668	0.331
X10-X19 Contact with heat and hot substances	0.668	0.331
X00-X09 Exposure to smoke, fire and flames	0.668	0.331
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.668	0.331
W75-W84 Other accidental threats to breathing	0.668	0.331
W65-W74 Accidental drowning and submersion	0.668	0.331
W50-W64 Exposure to animate mechanical forces	0.668	0.331
W20-W49 Exposure to inanimate mechanical forces	0.668	0.331
V98-V99 Other and unspecified transport accidents	0.668	0.331
V95-V97 Air and space transport accidents	0.668	0.331
V90-V94 Water transport accidents	0.668	0.331
V80-V89 Other land transport accidents	0.668	0.331
V70-V79 Bus occupant injured in transport accident	0.668	0.331
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.668	0.331
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.668	0.331
V40-V49 Car occupant injured in transport accident	0.668	0.331
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.668	0.331
V20-V29 Motorcycle rider injured in transport accident	0.668	0.331
V01-V09 Pedestrian injured in transport accident	0.668	0.331
E11.4 With neurological complications	0.668	0.332
C50.2 Upper-inner quadrant of breast	0.666	0.334
W00-W19 Falls	0.665	0.335
A08.4 Viral intestinal infection, unspecified	0.664	0.336
E11.3 With ophthalmic complications	0.663	0.337
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.662	0.338
M80 Osteoporosis with pathological fracture	0.662	0.338
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.662	0.338
O46.9 Antepartum haemorrhage, unspecified	0.662	0.338
N75 Diseases of Bartholin's gland	0.661	0.339
G46 Vascular syndromes of brain in cerebrovascular diseases	0.660	0.339
G41 Status epilepticus	0.660	0.339
D70 Agranulocytosis	0.659	0.341
H90-H95 Other disorders of ear	0.656	0.343
Y95 Nosocomial condition	0.656	0.344
G83 Other paralytic syndromes	0.655	0.345
G82 Paraplegia and tetraplegia	0.655	0.345
G80 Infantile cerebral palsy	0.655	0.345
D22.7 Melanocytic naevi of lower limb, including hip	0.655	0.345
M49 Spondylopathies in diseases classified elsewhere	0.653	0.347
M45 Ankylosing spondylitis	0.653	0.347
C51-C58 Malignant neoplasms of female genital organs	0.652	0.347
G62 Other polyneuropathies	0.652	0.348
O03 Spontaneous abortion	0.652	0.348
I67.8 Other specified cerebrovascular diseases	0.651	0.349
N61 Inflammatory disorders of breast	0.651	0.349
E88 Other metabolic disorders	0.649	0.350
E85 Amyloidosis	0.649	0.350
E84 Cystic fibrosis	0.649	0.350
E80 Disorders of porphyrin and bilirubin metabolism	0.649	0.350
E79 Disorders of purine and pyrimidine metabolism	0.649	0.350
E77 Disorders of glycoprotein metabolism	0.649	0.350
E76 Disorders of glycosaminoglycan metabolism	0.649	0.350
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.649	0.350
E74 Other disorders of carbohydrate metabolism	0.649	0.350
E73 Lactose intolerance	0.649	0.350
E72 Other disorders of amino-acid metabolism	0.649	0.350
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.649	0.350
E70 Disorders of aromatic amino-acid metabolism	0.649	0.350
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.649	0.350
C83 Diffuse non-Hodgkin's lymphoma	0.649	0.351
D80-D89 Certain disorders involving the immune mechanism	0.649	0.351
D55-D59 Haemolytic anaemias	0.649	0.351
N72 Inflammatory disease of cervix uteri	0.648	0.352
T92 Sequelae of injuries of upper limb	0.648	0.352
E16 Other disorders of pancreatic internal secretion	0.647	0.353
N62 Hypertrophy of breast	0.646	0.354
C50.6 Axillary tail of breast	0.646	0.354
C50.5 Lower-outer quadrant of breast	0.646	0.354
C50.3 Lower-inner quadrant of breast	0.646	0.354
C50.1 Central portion of breast	0.646	0.354
C43.6 Malignant melanoma of upper limb, including shoulder	0.646	0.354
H35 Other retinal disorders	0.645	0.354
D23.6 Skin of upper limb, including shoulder	0.645	0.355
C79.9 Secondary malignant neoplasm, unspecified site	0.645	0.355
C79.7 Secondary malignant neoplasm of adrenal gland	0.645	0.355
C79.6 Secondary malignant neoplasm of ovary	0.645	0.355
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.645	0.355
C79.2 Secondary malignant neoplasm of skin	0.645	0.355
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.645	0.355
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.645	0.355
H65-H75 Diseases of middle ear and mastoid	0.644	0.356
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.643	0.357
C90 Multiple myeloma and malignant plasma cell neoplasms	0.642	0.357
E05 Thyrotoxicosis [hyperthyroidism]	0.641	0.358
I73 Other peripheral vascular diseases	0.642	0.358
M20.6 Acquired deformity of toe(s), unspecified	0.641	0.359
M50-M54 Other dorsopathies	0.639	0.361
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.639	0.361
O36 Maternal care for other known or suspected foetal problems	0.639	0.361
M20.5 Other deformities of toe(s) (acquired)	0.638	0.362
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.638	0.362
H60-H62 Diseases of external ear	0.637	0.363
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.637	0.363
S70-S79 Injuries to the hip and thigh	0.636	0.364
I23 Certain current complications following acute myocardial infarction	0.635	0.365
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.634	0.366
G40.9 Epilepsy, unspecified	0.634	0.366
G99 Other disorders of nervous system in diseases classified elsewhere	0.633	0.367
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.632	0.368
S00-S09 Injuries to the head	0.631	0.369
I95-I99 Other and unspecified disorders of the circulatory system	0.631	0.369
I15 Secondary hypertension	0.631	0.369
I13 Hypertensive heart and renal disease	0.631	0.369
I11 Hypertensive heart disease	0.631	0.369
M81.9 Osteoporosis, unspecified	0.631	0.369
M20.0 Deformity of finger(s)	0.631	0.369
N13 Obstructive and reflux uropathy	0.630	0.370
E14.8 With unspecified complications	0.630	0.370
E14.7 With multiple complications	0.630	0.370
E14.6 With other specified complications	0.630	0.370
E14.5 With peripheral circulatory complications	0.630	0.370
E14.4 With neurological complications	0.630	0.370
E14.3 With ophthalmic complications	0.630	0.370
E14.2 Withrenal complications	0.630	0.370
E14.1 With ketoacidosis	0.630	0.370
E14.0 With coma	0.630	0.370
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.629	0.371
Y86 Sequelae of other accidents	0.629	0.371
Y85 Sequelae of transport accidents	0.629	0.371
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.628	0.372
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.627	0.372
Y43 Primarily systemic agents	0.626	0.373
M31 Other necrotising vasculopathies	0.625	0.374
M48.0 Spinal stenosis	0.625	0.375
M47.82 Other spondylosis (Cervical region)	0.625	0.375
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.624	0.376
E87.4 Mixed disorder of acid-base balance	0.624	0.376
E87.3 Alkalosis	0.624	0.376
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.623	0.377
R50-R69 General symptoms and signs	0.621	0.379
F00-F09 Organic, including symptomatic, mental disorders	0.621	0.379
S82.8 Fractures of other parts of lower leg	0.621	0.379
E03.9 Hypothyroidism, unspecified	0.619	0.381
G81.1 Spastic hemiplegia	0.619	0.381
G81.0 Flaccid hemiplegia	0.619	0.381
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.618	0.382
M34 Systemic sclerosis	0.618	0.382
M33 Dermatopolymyositis	0.618	0.382
M32 Systemic lupus erythematosus	0.618	0.382
M30 Polyarteritis nodosa and related conditions	0.618	0.382
M22 Disorders of patella	0.618	0.382
M21 Other acquired deformities of limbs	0.618	0.382
I67.1 Cerebral aneurysm, nonruptured	0.618	0.382
I12 Hypertensive renal disease	0.618	0.382
I24 Other acute ischaemic heart diseases	0.618	0.382
I77 Other disorders of arteries and arterioles	0.618	0.382
M85 Other disorders of bone density and structure	0.617	0.383
M83 Adult osteomalacia	0.617	0.383
M82 Osteoporosis in diseases classified elsewhere	0.617	0.383
E04 Other non-toxic goitre	0.616	0.384
D25 Leiomyoma of uterus	0.616	0.384
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.616	0.384
D22.9 Melanocytic naevi, unspecified	0.613	0.387
D22.2 Melanocytic naevi of ear and external auricular canal	0.613	0.387
D22.1 Melanocytic naevi of eyelid, including canthus	0.613	0.387
D22.0 Melanocytic naevi of lip	0.613	0.387
M47.92 Spondylosis, unspecified (Cervical region)	0.612	0.387
D22.4 Melanocytic naevi of scalp and neck	0.612	0.388
S82.4 Fracture of fibula alone	0.608	0.392
M20.4 Other hammer toe(s) (acquired)	0.608	0.392
D27 Benign neoplasm of ovary	0.608	0.392
D69 Purpura and other haemorrhagic conditions	0.608	0.392
E07 Other disorders of thyroid	0.606	0.394
E06 Thyroiditis	0.606	0.394
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.606	0.394
E00 Congenital iodine-deficiency syndrome	0.606	0.394
E02 Subclinical iodine-deficiency hypothyroidism	0.606	0.394
N63 Unspecified lump in breast	0.606	0.394
O20 Haemorrhage in early pregnancy	0.605	0.395
D23.7 Skin of lower limb, including hip	0.605	0.395
M19 Other arthrosis	0.604	0.396
C44.0 Skin of lip	0.604	0.396
B25-B34 Other viral diseases	0.604	0.396
F40 Phobic anxiety disorders	0.604	0.396
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.604	0.396
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.603	0.397
E87.1 Hypo-osmolality and hyponatraemia	0.603	0.397
E87.7 Fluid overload	0.603	0.397
E55 Vitamin D deficiency	0.602	0.398
Y44 Agents primarily affecting blood constituents	0.601	0.399
N30-N39 Other diseases of urinary system	0.600	0.400
G91 Hydrocephalus	0.599	0.401
N60 Benign mammary dysplasia	0.599	0.401
S89 Other and unspecified injuries of lower leg	0.598	0.402
S88 Traumatic amputation of lower leg	0.598	0.402
S87 Crushing injury of lower leg	0.598	0.402
S86 Injury of muscle and tendon at lower leg level	0.598	0.402
S85 Injury of blood vessels at lower leg level	0.598	0.402
S84 Injury of nerves at lower leg level	0.598	0.402
S81 Open wound of lower leg	0.598	0.402
S80 Superficial injury of lower leg	0.598	0.402
O02 Other abnormal products of conception	0.598	0.402
M47.2 Other spondylosis with radiculopathy	0.598	0.402
M47.1 Other spondylosis with myelopathy	0.598	0.402
M47.0 Anterior spinal and vertebral artery compression syndromes	0.598	0.402
A04.7 Enterocolitis due to Clostridium difficile	0.597	0.402
S66 Injury of muscle and tendon at wrist and hand level	0.597	0.403
B37.8 Candidiasis of other sites	0.597	0.403
A04.9 Bacterial intestinal infection, unspecified	0.596	0.404
A04.6 Enteritis due to Yersinia enterocolitica	0.596	0.404
A04.5 Campylobacter enteritis	0.596	0.404
A04.4 Other intestinal Escherichia coli infections	0.596	0.404
A04.3 Enterohaemorrhagic Escherichia coli infection	0.596	0.404
A04.2 Enteroinvasive Escherichia coli infection	0.596	0.404
A04.1 Enterotoxigenic Escherichia coli infection	0.596	0.404
A04.0 Enteropathogenic Escherichia coli infection	0.596	0.404
F30-F39 Mood [affective] disorders	0.596	0.404
N25-N29 Other disorders of kidney and ureter	0.595	0.405
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.594	0.405
C95 Leukaemia of unspecified cell type	0.594	0.405
C94 Other leukaemias of specified cell type	0.594	0.405
C93 Monocytic leukaemia	0.594	0.405
C92 Myeloid leukaemia	0.594	0.405
C91 Lymphoid leukaemia	0.594	0.405
C88 Malignant immunoproliferative diseases	0.594	0.405
C86 Other specified types of T/NK-cell lymphoma	0.594	0.405
C84 Peripheral and cutaneous T-cell lymphomas	0.594	0.405
C81 Hodgkin's disease	0.594	0.405
S42 Fracture of shoulder and upper arm	0.594	0.406
I20.8 Other forms of angina pectoris	0.593	0.406
H55-H59 Other disorders of eye and adnexa	0.593	0.407
H46-H48 Disorders of optic nerve and visual pathways	0.593	0.407
H10-H13 Disorders of conjunctiva	0.593	0.407
C25 Malignant neoplasm of pancreas	0.593	0.407
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.592	0.407
F41 Other anxiety disorders	0.592	0.408
O72 Postpartum haemorrhage	0.592	0.408

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations