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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79294993
log Bayes Factor = 19.4903
Chromosome 18   position 48,600,991  (GRCh37) Explore rs79294993 on Ensembl!
Variant rs79294993 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
M25 Other joint disorders, not elsewhere classified
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.994 0.006 0.000
M25.5 Pain in joint
0.993 0.007 0.000
S00-S09 Injuries to the head
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
M50-M54 Other dorsopathies
0.990 0.010 0.000
Chapter II Neoplasms
0.983 0.017 0.000
M06 Other rheumatoid arthritis
0.982 0.018 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.979 0.021 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.976 0.024 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
M06.9 Rheumatoid arthritis, unspecified
0.974 0.026 0.000
R50-R69 General symptoms and signs
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.970 0.030 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.969 0.031 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
M51 Other intervertebral disk disorders
0.966 0.034 0.000
B95-B98 Bacterial, viral and other infectious agents
0.962 0.038 0.000
Y95 Nosocomial condition
0.961 0.039 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.957 0.043 0.000
M25.56 Pain in joint (Lower leg)
0.954 0.046 0.000
M51.2 Other specified intervertebral disk displacement
0.948 0.052 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.948 0.052 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.945 0.055 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.933 0.067 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.933 0.067 0.000
R69 Unknown and unspecified causes of morbidity
0.932 0.068 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.931 0.069 0.000
F32 Depressive episode
0.931 0.069 0.000
S01 Open wound of head
0.923 0.077 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.922 0.078 0.000
C15 Malignant neoplasm of oesophagus
0.922 0.078 0.000
Chapter X Diseases of the respiratory system
0.921 0.079 0.000
M15-M19 Arthrosis
0.920 0.080 0.000
M21 Other acquired deformities of limbs
0.919 0.081 0.000
F10.0 Acute intoxication
0.919 0.081 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.918 0.082 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.913 0.087 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.909 0.091 0.000
R59 Enlarged lymph nodes
0.909 0.091 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.907 0.093 0.000
F17.1 Harmful use
0.905 0.095 0.000
S00 Superficial injury of head
0.905 0.095 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.903 0.097 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.901 0.099 0.000
M25.7 Osteophyte
0.898 0.102 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.898 0.102 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.896 0.104 0.000
F17.2 Dependence syndrome
0.895 0.105 0.000
M23 Internal derangement of knee
0.893 0.107 0.000
F32.9 Depressive episode, unspecified
0.889 0.111 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
W00-W19 Falls
0.884 0.116 0.000
J95-J99 Other diseases of the respiratory system
0.884 0.116 0.000
M13 Other arthritis
0.883 0.117 0.000
C34 Malignant neoplasm of bronchus and lung
0.880 0.120 0.000
T43.2 Other and unspecified antidepressants
0.879 0.121 0.000
F60-F69 Disorders of adult personality and behaviour
0.873 0.127 0.000
S90-S99 Injuries to the ankle and foot
0.871 0.129 0.000
R63 Symptoms and signs concerning food and fluid intake
0.870 0.130 0.000
T51 Toxic effect of alcohol
0.870 0.130 0.000
B35-B49 Mycoses
0.863 0.136 0.000
S06 Intracranial injury
0.863 0.137 0.000
C15.9 Oesophagus, unspecified
0.863 0.137 0.000
S01.0 Open wound of scalp
0.861 0.139 0.000
F33 Recurrent depressive disorder
0.859 0.141 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.859 0.141 0.000
M54 Dorsalgia
0.858 0.142 0.000
J98 Other respiratory disorders
0.857 0.143 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.856 0.144 0.000
R29.6 Tendency to fall, not elsewhere classified
0.855 0.145 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.851 0.149 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.849 0.151 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.847 0.153 0.000
M25.77 Osteophyte (Ankle and foot)
0.847 0.153 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.846 0.154 0.000
M25.8 Other specified joint disorders
0.844 0.156 0.000
C34.1 Upper lobe, bronchus or lung
0.843 0.157 0.000
F10.2 Dependence syndrome
0.840 0.160 0.000
M24 Other specific joint derangements
0.836 0.164 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.830 0.170 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.826 0.174 0.000
S02 Fracture of skull and facial bones
0.826 0.174 0.000
R52 Pain, not elsewhere classified
0.825 0.175 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.823 0.177 0.000
M25.57 Pain in joint (Ankle and foot)
0.822 0.178 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.821 0.179 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.818 0.182 0.000
R53 Malaise and fatigue
0.817 0.183 0.000
R59.9 Enlarged lymph nodes, unspecified
0.814 0.186 0.000
M50 Cervical disk disorders
0.814 0.186 0.000
C25 Malignant neoplasm of pancreas
0.812 0.187 0.000
S40-S49 Injuries to the shoulder and upper arm
0.812 0.188 0.000
S01.9 Open wound of head, part unspecified
0.812 0.188 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.811 0.189 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.810 0.190 0.000
T51.0 Ethanol
0.808 0.192 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.807 0.193 0.000
M13.9 Arthritis, unspecified
0.807 0.193 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.806 0.194 0.000
M86-M90 Other osteopathies
0.806 0.194 0.000
M23.4 Loose body in knee
0.805 0.195 0.000
R63.4 Abnormal weight loss
0.804 0.196 0.000
S60-S69 Injuries to the wrist and hand
0.803 0.197 0.000
R46 Symptoms and signs involving appearance and behaviour
0.803 0.197 0.000
R47-R49 Symptoms and signs involving speech and voice
0.802 0.198 0.000
Chapter VI Diseases of the nervous system
0.801 0.199 0.000
X20-X29 Contact with venomous animals and plants
0.800 0.200 0.000
J98.4 Other disorders of lung
0.799 0.201 0.000
Y86 Sequelae of other accidents
0.798 0.202 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.795 0.205 0.000
M25.53 Pain in joint (Forearm)
0.791 0.209 0.000
M91-M94 Chondropathies
0.790 0.210 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.789 0.211 0.000
M25.51 Pain in joint (Shoulder region)
0.789 0.211 0.000
M25.50 Pain in joint (Multiple sites)
0.788 0.211 0.000
W20-W49 Exposure to inanimate mechanical forces
0.787 0.213 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.787 0.213 0.000
B15-B19 Viral hepatitis
0.787 0.213 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.787 0.213 0.000
M45-M49 Spondylopathies
0.786 0.214 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.785 0.215 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.785 0.215 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.784 0.216 0.000
M34 Systemic sclerosis
0.784 0.216 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.784 0.216 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.783 0.217 0.000
M25.3 Other instability of joint
0.783 0.217 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.782 0.218 0.000
Chapter VIII Diseases of the ear and mastoid process
0.782 0.218 0.000
M21.3 Wrist or foot drop (acquired)
0.782 0.218 0.000
F60 Specific personality disorders
0.782 0.218 0.000
B37 Candidiasis
0.781 0.219 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.780 0.220 0.000
C16 Malignant neoplasm of stomach
0.780 0.220 0.000
M18 Arthrosis of first carpometacarpal joint
0.779 0.221 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.777 0.223 0.000
C15.5 Lower third of oesophagus
0.777 0.223 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.776 0.224 0.000
R25 Abnormal involuntary movements
0.776 0.224 0.000
M54.2 Cervicalgia
0.775 0.225 0.000
R59.0 Localised enlarged lymph nodes
0.775 0.225 0.000
M19 Other arthrosis
0.772 0.228 0.000
M70-M79 Other soft tissue disorders
0.771 0.229 0.000
C21 Malignant neoplasm of anus and anal canal
0.769 0.231 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.768 0.232 0.000
C18 Malignant neoplasm of colon
0.768 0.232 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.768 0.232 0.000
M65-M68 Disorders of synovium and tendon
0.766 0.234 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.764 0.236 0.000
Chapter IX Diseases of the circulatory system
0.764 0.236 0.000
T42.4 Benzodiazepines
0.760 0.240 0.000
R73 Elevated blood glucose level
0.760 0.240 0.000
F32.0 Mild depressive episode
0.759 0.241 0.000
R79 Other abnormal findings of blood chemistry
0.758 0.242 0.000
V80-V89 Other land transport accidents
0.755 0.244 0.000
S09 Other and unspecified injuries of head
0.755 0.245 0.000
M25.9 Joint disorder, unspecified
0.755 0.245 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.755 0.245 0.000
S00.5 Superficial injury of lip and oral cavity
0.754 0.246 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.754 0.246 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.754 0.246 0.000
C20 Malignant neoplasm of rectum
0.754 0.246 0.000
Chapter VII Diseases of the eye and adnexa
0.753 0.247 0.000
Chapter XIV Diseases of the genitourinary system
0.753 0.247 0.000
M25.54 Pain in joint (Hand)
0.752 0.248 0.000
C32 Malignant neoplasm of larynx
0.752 0.248 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.752 0.248 0.000
B99-B99 Other infectious diseases
0.752 0.248 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.751 0.249 0.000
L50-L54 Urticaria and erythema
0.751 0.249 0.000
R30-R39 Symptoms and signs involving the urinary system
0.751 0.249 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.750 0.250 0.000
J90-J94 Other diseases of pleura
0.750 0.250 0.000
M16 Coxarthrosis [arthrosis of hip]
0.749 0.251 0.000
F32.1 Moderate depressive episode
0.747 0.253 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.745 0.254 0.000
Chapter XXII Codes for special purposes
0.745 0.255 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.744 0.256 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.744 0.256 0.000
M21.4 Flat foot [pes planus] (acquired)
0.743 0.257 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.742 0.258 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.742 0.258 0.000
M23.49 Loose body in knee-Unspec lig/men
0.742 0.258 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.741 0.259 0.000
G90-G99 Other disorders of the nervous system
0.741 0.259 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.740 0.260 0.000
S00.1 Contusion of eyelid and periocular area
0.740 0.260 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.740 0.260 0.000
M05 Seropositive rheumatoid arthritis
0.740 0.260 0.000
R40 Somnolence, stupor and coma
0.739 0.261 0.000
R26 Abnormalities of gait and mobility
0.738 0.262 0.000
Y85 Sequelae of transport accidents
0.738 0.262 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.737 0.263 0.000
M20 Acquired deformities of fingers and toes
0.733 0.267 0.000
C51-C58 Malignant neoplasms of female genital organs
0.733 0.267 0.000
I95 Hypotension
0.733 0.267 0.000
T63 Toxic effect of contact with venomous animals
0.731 0.269 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.729 0.271 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.728 0.272 0.000
F99-F99 Unspecified mental disorder
0.728 0.272 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.727 0.273 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.725 0.275 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.725 0.275 0.000
R27 Other lack of coordination
0.725 0.275 0.000
T66-T78 Other and unspecified effects of external causes
0.725 0.275 0.000
S01.2 Open wound of nose
0.724 0.275 0.000
M21.6 Other acquired deformities of ankle and foot
0.724 0.276 0.000
I95.1 Orthostatic hypotension
0.724 0.276 0.000
M21.0 Valgus deformity, not elsewhere classified
0.722 0.278 0.000
Q60-Q64 Congenital malformations of the urinary system
0.722 0.278 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.722 0.278 0.000
R61 Hyperhidrosis
0.721 0.279 0.000
C73 Malignant neoplasm of thyroid gland
0.721 0.279 0.000
Y52 Agents primarily affecting the cardiovascular system
0.721 0.279 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.721 0.279 0.000
Y43 Primarily systemic agents
0.720 0.280 0.000
S92 Fracture of foot, except ankle
0.719 0.281 0.000
Q80-Q89 Other congenital malformations
0.718 0.282 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.718 0.282 0.000
M25.71 Osteophyte (Shoulder region)
0.718 0.282 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.717 0.282 0.000
W19 Unspecified fall
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
M25.2 Flail joint
0.716 0.284 0.000
M25.1 Fistula of joint
0.716 0.284 0.000
M25.0 Haemarthrosis
0.716 0.284 0.000
M54.22 Cervicalgia (Cervical region)
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
S60 Superficial injury of wrist and hand
0.715 0.285 0.000
M51.9 Intervertebral disk disorder, unspecified
0.715 0.285 0.000
J60-J70 Lung diseases due to external agents
0.714 0.286 0.000
R35 Polyuria
0.713 0.287 0.000
S62 Fracture at wrist and hand level
0.713 0.287 0.000
W17 Other fall from one level to another
0.713 0.287 0.000
Y57 Other and unspecified drugs and medicaments
0.713 0.287 0.000
M19.0 Primary arthrosis of other joints
0.713 0.287 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.712 0.287 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.712 0.287 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.712 0.287 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.712 0.287 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.712 0.287 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.712 0.287 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.712 0.287 0.000
F11 Mental and behavioural disorders due to use of opioids
0.712 0.287 0.000
M25.59 Pain in joint (Site unspecified)
0.712 0.288 0.000
M25.58 Pain in joint (Other)
0.712 0.288 0.000
M25.52 Pain in joint (Upper arm)
0.712 0.288 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.712 0.288 0.000
S08 Traumatic amputation of part of head
0.712 0.288 0.000
S07 Crushing injury of head
0.712 0.288 0.000
S05 Injury of eye and orbit
0.712 0.288 0.000
S04 Injury of cranial nerves
0.712 0.288 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.712 0.288 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
M07 Psoriatic and enteropathic arthropathies
0.711 0.289 0.000
M22 Disorders of patella
0.710 0.290 0.000
M53 Other dorsopathies, not elsewhere classified
0.710 0.290 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.290 0.000
M80-M85 Disorders of bone density and structure
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
M50.2 Other cervical disk displacement
0.704 0.296 0.000
S00.8 Superficial injury of other parts of head
0.704 0.296 0.000
M06.8 Other specified rheumatoid arthritis
0.704 0.296 0.000
M06.4 Inflammatory polyarthropathy
0.704 0.296 0.000
M06.3 Rheumatoid nodule
0.704 0.296 0.000
M06.2 Rheumatoid bursitis
0.704 0.296 0.000
M06.1 Adult-onset Still's disease
0.704 0.296 0.000
M25.84 Other specified joint disorders (Hand)
0.703 0.297 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.702 0.298 0.000
M06.0 Seronegative rheumatoid arthritis
0.701 0.299 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.701 0.299 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.700 0.300 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.700 0.300 0.000
Y98 Lifestyle-related condition
0.700 0.300 0.000
Y97 Environmental-pollution-related condition
0.700 0.300 0.000
Y96 Work-related condition
0.700 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.699 0.301 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.698 0.301 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.698 0.301 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.698 0.301 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.698 0.301 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.698 0.302 0.000
V20-V29 Motorcycle rider injured in transport accident
0.697 0.303 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.697 0.303 0.000
S00.0 Superficial injury of scalp
0.696 0.304 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.304 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.695 0.305 0.000
R62 Lack of expected normal physiological development
0.695 0.305 0.000
R64 Cachexia
0.695 0.305 0.000
R58 Haemorrhage, not elsewhere classified
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F34 Persistent mood [affective] disorders
0.695 0.305 0.000
F30 Manic episode
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.695 0.305 0.000
F17.9 Unspecified mental and behavioural disorder
0.695 0.305 0.000
F17.8 Other mental and behavioural disorders
0.695 0.305 0.000
F17.7 Residual and late-onset psychotic disorder
0.695 0.305 0.000
F17.6 Amnesic syndrome
0.695 0.305 0.000
F17.5 Psychotic disorder
0.695 0.305 0.000
F17.4 Withdrawal state with delirium
0.695 0.305 0.000
F17.3 Withdrawal state
0.695 0.305 0.000
F17.0 Acute intoxication
0.695 0.305 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.695 0.305 0.000
C34.3 Lower lobe, bronchus or lung
0.694 0.306 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.693 0.307 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.693 0.307 0.000
C17 Malignant neoplasm of small intestine
0.693 0.307 0.000
C23 Malignant neoplasm of gallbladder
0.693 0.307 0.000
M51.3 Other specified intervertebral disk degeneration
0.693 0.307 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.693 0.307 0.000
M51.8 Other specified intervertebral disk disorders
0.693 0.307 0.000
M51.4 Schmorl's nodes
0.693 0.307 0.000
F33.9 Recurrent depressive disorder, unspecified
0.693 0.307 0.000
V10-V19 Pedal cyclist injured in transport accident
0.692 0.307 0.000
N10-N16 Renal tubulo-interstitial diseases
0.691 0.309 0.000
S91 Open wound of ankle and foot
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.689 0.310 0.000
J90 Pleural effusion, not elsewhere classified
0.689 0.311 0.000
L50 Urticaria
0.689 0.311 0.000
R45 Symptoms and signs involving emotional state
0.688 0.312 0.000
T51.9 Alcohol, unspecified
0.688 0.312 0.000
T86 Failure and rejection of transplanted organs and tissues
0.688 0.312 0.000
R57 Shock, not elsewhere classified
0.687 0.313 0.000
C25.9 Pancreas, unspecified
0.687 0.313 0.000
R29.4 Clicking hip
0.686 0.314 0.000
R29.3 Abnormal posture
0.686 0.314 0.000
R29.2 Abnormal reflex
0.686 0.314 0.000
R29.1 Meningismus
0.686 0.314 0.000
R29.0 Tetany
0.686 0.314 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.686 0.314 0.000
W07 Fall involving chair
0.686 0.314 0.000
C71 Malignant neoplasm of brain
0.686 0.314 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.684 0.316 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.683 0.317 0.000
R59.1 Generalised enlarged lymph nodes
0.683 0.317 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.682 0.318 0.000
J09-J18 Influenza and pneumonia
0.681 0.318 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.681 0.319 0.000
M13.94 Arthritis, unspecified (Hand)
0.681 0.319 0.000
B37.9 Candidiasis, unspecified
0.681 0.319 0.000
R46.2 Strange and inexplicable behaviour
0.680 0.320 0.000
R52.1 Chronic intractable pain
0.680 0.320 0.000
T43.9 Psychotropic drug, unspecified
0.679 0.320 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.679 0.320 0.000
T43.6 Psychostimulants with abuse potential
0.679 0.320 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.679 0.320 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.679 0.320 0.000
F60.9 Personality disorder, unspecified
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.679 0.321 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.678 0.322 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.677 0.323 0.000
F10.9 Unspecified mental and behavioural disorder
0.677 0.323 0.000
F10.8 Other mental and behavioural disorders
0.677 0.323 0.000
F10.7 Residual and late-onset psychotic disorder
0.677 0.323 0.000
F10.6 Amnesic syndrome
0.677 0.323 0.000
F10.5 Psychotic disorder
0.677 0.323 0.000
F10.4 Withdrawal state with delirium
0.677 0.323 0.000
M47 Spondylosis
0.677 0.323 0.000
R52.2 Other chronic pain
0.677 0.323 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
N20-N23 Urolithiasis
0.675 0.325 0.000
M24.0 Loose body in joint
0.674 0.326 0.000
S02.8 Fractures of other skull and facial bones
0.673 0.326 0.000
T40.2 Other opioids
0.673 0.327 0.000
S01.3 Open wound of ear
0.672 0.328 0.000
S06.5 Traumatic subdural haemorrhage
0.672 0.328 0.000
T39.0 Salicylates
0.672 0.328 0.000
C85.1 B-cell lymphoma, unspecified
0.671 0.329 0.000
L82 Seborrhoeic keratosis
0.671 0.329 0.000
R47 Speech disturbances, not elsewhere classified
0.670 0.330 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.670 0.330 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.669 0.331 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.669 0.331 0.000
C31 Malignant neoplasm of accessory sinuses
0.669 0.331 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.669 0.331 0.000
C37 Malignant neoplasm of thymus
0.669 0.331 0.000
C33 Malignant neoplasm of trachea
0.669 0.331 0.000
T65 Toxic effect of other and unspecified substances
0.669 0.331 0.000
T62 Toxic effect of other noxious substances eaten as food
0.669 0.331 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.669 0.331 0.000
T60 Toxic effect of pesticides
0.669 0.331 0.000
T59 Toxic effect of other gases, fumes and vapours
0.669 0.331 0.000
T57 Toxic effect of other inorganic substances
0.669 0.331 0.000
T56 Toxic effect of metals
0.669 0.331 0.000
T54 Toxic effect of corrosive substances
0.669 0.331 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.669 0.331 0.000
T52 Toxic effect of organic solvents
0.669 0.331 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.669 0.331 0.000
T58 Toxic effect of carbon monoxide
0.669 0.331 0.000
T55 Toxic effect of soaps and detergents
0.669 0.331 0.000
R41.3 Other amnesia
0.668 0.332 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.668 0.332 0.000
M23.3 Other meniscus derangements
0.668 0.332 0.000
F32.8 Other depressive episodes
0.667 0.332 0.000
M11 Other crystal arthropathies
0.667 0.333 0.000
W18 Other fall on same level
0.665 0.334 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.665 0.335 0.000
R60 Oedema, not elsewhere classified
0.664 0.336 0.000
C64-C68 Malignant neoplasms of urinary tract
0.662 0.338 0.000
H53-H54 Visual disturbances and blindness
0.662 0.338 0.000
S01.7 Multiple open wounds of head
0.661 0.338 0.000
S01.4 Open wound of cheek and temporomandibular area
0.661 0.338 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.661 0.339 0.000
R77 Other abnormalities of plasma proteins
0.661 0.339 0.000
R76 Other abnormal immunological findings in serum
0.661 0.339 0.000
R74 Abnormal serum enzyme levels
0.661 0.339 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.661 0.339 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.661 0.339 0.000
R71 Abnormality of red blood cells
0.661 0.339 0.000
C15.8 Overlapping lesion of oesophagus
0.661 0.339 0.000
C15.4 Middle third of oesophagus
0.661 0.339 0.000
C15.3 Upper third of oesophagus
0.661 0.339 0.000
C15.2 Abdominal part of oesophagus
0.661 0.339 0.000
C15.1 Thoracic part of oesophagus
0.661 0.339 0.000
C15.0 Cervical part of oesophagus
0.661 0.339 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.660 0.340 0.000
M16.9 Coxarthrosis, unspecified
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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