TreeWAS – Variant ID: rs79490353

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001
E00-E07 Disorders of thyroid gland	0.999	0.001
I25 Chronic ischaemic heart disease	0.999	0.001
E03 Other hypothyroidism	0.997	0.003
E03.9 Hypothyroidism, unspecified	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004
I05-I09 Chronic rheumatic heart diseases	0.988	0.012
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.986	0.014
I50 Heart failure	0.984	0.016
I35 Nonrheumatic aortic valve disorders	0.980	0.020
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.979	0.021
D80-D89 Certain disorders involving the immune mechanism	0.977	0.023
I25.1 Atherosclerotic heart disease	0.977	0.023
S00-S09 Injuries to the head	0.976	0.024
I08 Multiple valve diseases	0.970	0.030
E70-E90 Metabolic disorders	0.965	0.035
I60-I69 Cerebrovascular diseases	0.964	0.036
I25.8 Other forms of chronic ischaemic heart disease	0.962	0.038
I51 Complications and ill-defined descriptions of heart disease	0.953	0.047
I50.1 Left ventricular failure	0.948	0.052
D86 Sarcoidosis	0.945	0.055
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.944	0.056
I21 Acute myocardial infarction	0.942	0.058
E20-E35 Disorders of other endocrine glands	0.940	0.060
I25.9 Chronic ischaemic heart disease, unspecified	0.938	0.062
I51.7 Cardiomegaly	0.938	0.062
S09 Other and unspecified injuries of head	0.937	0.063
M40-M43 Deforming dorsopathies	0.932	0.068
I08.0 Disorders of both mitral and aortic valves	0.929	0.071
I35.1 Aortic (valve) insufficiency	0.926	0.074
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.924	0.076
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.918	0.082
Chapter XX External causes of morbidity and mortality	0.911	0.089
T66-T78 Other and unspecified effects of external causes	0.904	0.095
S09.9 Unspecified injury of head	0.900	0.100
I50.9 Heart failure, unspecified	0.897	0.103
E87 Other disorders of fluid, electrolyte and acid-base balance	0.896	0.104
M43 Other deforming dorsopathies	0.892	0.108
S40-S49 Injuries to the shoulder and upper arm	0.890	0.110
S02 Fracture of skull and facial bones	0.889	0.111
I05 Rheumatic mitral valve diseases	0.889	0.111
I34 Nonrheumatic mitral valve disorders	0.880	0.120
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.879	0.121
I10-I15 Hypertensive diseases	0.877	0.123
M70-M79 Other soft tissue disorders	0.869	0.131
Chapter VII Diseases of the eye and adnexa	0.868	0.132
D86.0 Sarcoidosis of lung	0.866	0.134
E05 Thyrotoxicosis [hyperthyroidism]	0.865	0.135
S70-S79 Injuries to the hip and thigh	0.864	0.136
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.859	0.141
M43.1 Spondylolisthesis	0.857	0.143
I69 Sequelae of cerebrovascular disease	0.856	0.144
M45-M49 Spondylopathies	0.851	0.149
I12 Hypertensive renal disease	0.848	0.152
D69 Purpura and other haemorrhagic conditions	0.846	0.154
I35.2 Aortic (valve) stenosis with insufficiency	0.845	0.155
D60-D64 Aplastic and other anaemias	0.845	0.155
I21.1 Acute transmural myocardial infarction of inferior wall	0.842	0.158
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.839	0.161
M43.16 Spondylolisthesis (Lumbar region)	0.838	0.162
I64 Stroke, not specified as haemorrhage or infarction	0.837	0.163
S20-S29 Injuries to the thorax	0.833	0.167
M65-M68 Disorders of synovium and tendon	0.830	0.170
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.829	0.171
H30-H36 Disorders of choroid and retina	0.828	0.172
I63 Cerebral infarction	0.827	0.173
I35.0 Aortic (valve) stenosis	0.826	0.174
I08.1 Disorders of both mitral and tricuspid valves	0.826	0.174
I08.8 Other multiple valve diseases	0.824	0.176
D86.9 Sarcoidosis, unspecified	0.823	0.177
T85 Complications of other internal prosthetic devices, implants and grafts	0.820	0.180
T84.1 Mechanical complication of internal fixation device of bones of limb	0.815	0.185
D69.6 Thrombocytopenia, unspecified	0.809	0.191
Y83.1 Surgical operation with implant of artificial internal device	0.806	0.194
E22 Hyperfunction of pituitary gland	0.806	0.194
Y83.2 Surgical operation with anastomosis, bypass or graft	0.804	0.196
E83 Disorders of mineral metabolism	0.802	0.198
I21.2 Acute transmural myocardial infarction of other sites	0.802	0.198
E40-E46 Malnutrition	0.793	0.207
T83.1 Mechanical complication of other urinary devices and implants	0.791	0.209
D55-D59 Haemolytic anaemias	0.791	0.209
I12.0 Hypertensive renal disease with renal failure	0.791	0.209
M91-M94 Chondropathies	0.789	0.210
E86 Volume depletion	0.789	0.211
I36 Nonrheumatic tricuspid valve disorders	0.788	0.212
E65-E68 Obesity and other hyperalimentation	0.788	0.212
S46 Injury of muscle and tendon at shoulder and upper arm level	0.785	0.215
M86-M90 Other osteopathies	0.782	0.218
Chapter X Diseases of the respiratory system	0.782	0.218
M79 Other soft tissue disorders, not elsewhere classified	0.782	0.218
D86.1 Sarcoidosis of lymph nodes	0.779	0.220
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.778	0.222
T84.3 Mechanical complication of other bone devices, implants and grafts	0.777	0.223
I60 Subarachnoid haemorrhage	0.776	0.224
E29 Testicular dysfunction	0.776	0.224
Chapter XXII Codes for special purposes	0.774	0.226
S05 Injury of eye and orbit	0.774	0.226
D50-D53 Nutritional anaemias	0.773	0.227
S10-S19 Injuries to the neck	0.773	0.227
I25.2 Old myocardial infarction	0.771	0.229
I21.3 Acute transmural myocardial infarction of unspecified site	0.771	0.229
E03.8 Other specified hypothyroidism	0.768	0.232
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.767	0.233
M50-M54 Other dorsopathies	0.767	0.233
E87.2 Acidosis	0.767	0.233
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.763	0.237
I12.9 Hypertensive renal disease without renal failure	0.763	0.237
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.762	0.238
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.760	0.240
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.760	0.240
T86 Failure and rejection of transplanted organs and tissues	0.759	0.241
I05.0 Mitral stenosis	0.758	0.242
D80 Immunodeficiency with predominantly antibody defects	0.757	0.243
T78 Adverse effects, not elsewhere classified	0.756	0.244
M46 Other inflammatory spondylopathies	0.755	0.245
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.754	0.246
T83.0 Mechanical complication of urinary (indwelling) catheter	0.753	0.246
I38 Endocarditis, valve unspecified	0.751	0.249
E06 Thyroiditis	0.750	0.250
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.750	0.250
I70-I79 Diseases of arteries, arterioles and capillaries	0.749	0.251
I33 Acute and subacute endocarditis	0.748	0.251
I34.0 Mitral (valve) insufficiency	0.747	0.253
S02.4 Fracture of malar and maxillary bones	0.747	0.253
M48 Other spondylopathies	0.746	0.254
S06 Intracranial injury	0.746	0.254
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.745	0.255
Y83.4 Other reconstructive surgery	0.744	0.256
S90-S99 Injuries to the ankle and foot	0.743	0.257
E87.6 Hypokalaemia	0.740	0.260
S02.8 Fractures of other skull and facial bones	0.740	0.260
T68 Hypothermia	0.739	0.261
E10-E14 Diabetes mellitus	0.737	0.263
I08.2 Disorders of both aortic and tricuspid valves	0.737	0.263
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.736	0.264
M65 Synovitis and tenosynovitis	0.735	0.265
S09.8 Other specified injuries of head	0.735	0.265
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.735	0.265
H10-H13 Disorders of conjunctiva	0.734	0.266
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.733	0.267
I22 Subsequent myocardial infarction	0.733	0.267
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.733	0.267
E88 Other metabolic disorders	0.731	0.269
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.731	0.269
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.730	0.270
T80 Complications following infusion, transfusion and therapeutic injection	0.730	0.270
I63.9 Cerebral infarction, unspecified	0.729	0.271
T87 Complications peculiar to reattachment and amputation	0.729	0.271
I25.3 Aneurysm of heart	0.727	0.272
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.727	0.273
H36 Retinal disorders in diseases classified elsewhere	0.727	0.273
H35 Other retinal disorders	0.724	0.276
T75 Effects of other external causes	0.723	0.277
D89.2 Hypergammaglobulinaemia, unspecified	0.723	0.277
J30-J39 Other diseases of upper respiratory tract	0.722	0.278
E50-E64 Other nutritional deficiencies	0.722	0.278
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.720	0.280
H33 Retinal detachments and breaks	0.717	0.283
E87.7 Fluid overload	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E34 Other endocrine disorders	0.717	0.283
I21.4 Acute subendocardial myocardial infarction	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I30 Acute pericarditis	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.716	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284
E00 Congenital iodine-deficiency syndrome	0.716	0.284
E02 Subclinical iodine-deficiency hypothyroidism	0.716	0.284
I25.6 Silent myocardial ischaemia	0.716	0.284
I25.4 Coronary artery aneurysm	0.716	0.284
I25.0 Atherosclerotic cardiovascular disease, so described	0.716	0.284
E03.5 Myxoedema coma	0.715	0.285
E03.4 Atrophy of thyroid (acquired)	0.715	0.285
E03.3 Postinfectious hypothyroidism	0.715	0.285
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.715	0.285
E03.1 Congenital hypothyroidism without goitre	0.715	0.285
E03.0 Congenital hypothyroidism with diffuse goitre	0.715	0.285
D68 Other coagulation defects	0.715	0.285
I46 Cardiac arrest	0.715	0.285
Chapter I Certain infectious and parasitic diseases	0.714	0.286
S41 Open wound of shoulder and upper arm	0.713	0.287
I50.0 Congestive heart failure	0.713	0.287
M41 Scoliosis	0.712	0.288
J40-J47 Chronic lower respiratory diseases	0.712	0.288
S46.0 Injury of tendon of the rotator cuff of shoulder	0.710	0.290
E23 Hypofunction and other disorders of pituitary gland	0.709	0.290
D51 Vitamin B12 deficiency anaemia	0.709	0.291
I09 Other rheumatic heart diseases	0.708	0.291
I06 Rheumatic aortic valve diseases	0.708	0.291
I05.1 Rheumatic mitral insufficiency	0.708	0.292
S22 Fracture of rib(s), sternum and thoracic spine	0.708	0.292
M05-M14 Inflammatory polyarthropathies	0.705	0.295
E83.5 Disorders of calcium metabolism	0.703	0.297
I35.9 Aortic valve disorder, unspecified	0.702	0.298
I35.8 Other aortic valve disorders	0.702	0.298
M60-M63 Disorders of muscles	0.702	0.298
E80 Disorders of porphyrin and bilirubin metabolism	0.702	0.298
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.701	0.299
D84 Other immunodeficiencies	0.700	0.299
D83 Common variable immunodeficiency	0.700	0.299
D82 Immunodeficiency associated with other major defects	0.700	0.299
D81 Combined immunodeficiencies	0.700	0.299
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.700	0.299
S08 Traumatic amputation of part of head	0.700	0.300
S07 Crushing injury of head	0.700	0.300
S04 Injury of cranial nerves	0.700	0.300
S03 Dislocation, sprain and strain of joints and ligaments of head	0.700	0.300
E05.9 Thyrotoxicosis, unspecified	0.699	0.301
I05.9 Mitral valve disease, unspecified	0.699	0.301
M00-M03 Infectious arthropathies	0.698	0.302
X20-X29 Contact with venomous animals and plants	0.698	0.302
I08.9 Multiple valve disease, unspecified	0.695	0.305
I49 Other cardiac arrhythmias	0.695	0.305
E85 Amyloidosis	0.692	0.308
E84 Cystic fibrosis	0.692	0.308
E79 Disorders of purine and pyrimidine metabolism	0.692	0.308
E77 Disorders of glycoprotein metabolism	0.692	0.308
E76 Disorders of glycosaminoglycan metabolism	0.692	0.308
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.692	0.308
E74 Other disorders of carbohydrate metabolism	0.692	0.308
E73 Lactose intolerance	0.692	0.308
E72 Other disorders of amino-acid metabolism	0.692	0.308
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.692	0.308
E70 Disorders of aromatic amino-acid metabolism	0.692	0.308
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.692	0.308
I68 Cerebrovascular disorders in diseases classified elsewhere	0.691	0.309
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.691	0.309
E05.0 Thyrotoxicosis with diffuse goitre	0.691	0.309
M43.0 Spondylolysis	0.688	0.312
E87.0 Hyperosmolality and hypernatraemia	0.687	0.313
T88 Other complications of surgical and medical care, not elsewhere classified	0.686	0.314
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.686	0.314
J33 Nasal polyp	0.686	0.314
E07 Other disorders of thyroid	0.685	0.315
M46.9 Inflammatory spondylopathy, unspecified	0.685	0.315
J47 Bronchiectasis	0.685	0.315
E27 Other disorders of adrenal gland	0.685	0.315
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.684	0.316
S71 Open wound of hip and thigh	0.684	0.316
I51.6 Cardiovascular disease, unspecified	0.683	0.316
I51.5 Myocardial degeneration	0.683	0.316
I51.4 Myocarditis, unspecified	0.683	0.316
I51.3 Intracardiac thrombosis, not elsewhere classified	0.683	0.316
I51.2 Rupture of papillary muscle, not elsewhere classified	0.683	0.316
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.683	0.316
I51.0 Cardiac septal defect, acquired	0.683	0.316
Q50-Q56 Congenital malformations of genital organs	0.682	0.318
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.681	0.319
S70 Superficial injury of hip and thigh	0.681	0.319
S02.3 Fracture of orbital floor	0.681	0.319
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.680	0.320
M79.6 Pain in limb	0.679	0.321
M77 Other enthesopathies	0.679	0.321
Q80-Q89 Other congenital malformations	0.678	0.322
W50-W64 Exposure to animate mechanical forces	0.678	0.322
D86.8 Sarcoidosis of other and combined sites	0.678	0.322
D86.3 Sarcoidosis of skin	0.678	0.322
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.678	0.322
I34.1 Mitral (valve) prolapse	0.676	0.324
I45 Other conduction disorders	0.676	0.324
I21.X Presumed acute myicardial infaction (unconfirmed)	0.675	0.324
M79.8 Other specified soft tissue disorders	0.675	0.325
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.675	0.325
S40 Superficial injury of shoulder and upper arm	0.674	0.325
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.674	0.326
D63 Anaemia in chronic diseases classified elsewhere	0.674	0.326
E35 Disorders of endocrine glands in diseases classified elsewhere	0.674	0.326
E32 Diseases of thymus	0.674	0.326
E31 Polyglandular dysfunction	0.674	0.326
E30 Disorders of puberty, not elsewhere classified	0.674	0.326
E26 Hyperaldosteronism	0.674	0.326
E25 Adrenogenital disorders	0.674	0.326
E24 Cushing's syndrome	0.674	0.326
E20 Hypoparathyroidism	0.674	0.326
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.674	0.326
I21.9 Acute myocardial infarction, unspecified	0.674	0.326
S09.7 Multiple injuries of head	0.672	0.328
S09.2 Traumatic rupture of ear drum	0.672	0.328
S09.1 Injury of muscle and tendon of head	0.672	0.328
S09.0 Injury of blood vessels of head, not elsewhere classified	0.672	0.328
M48.0 Spinal stenosis	0.670	0.330
S02.1 Fracture of base of skull	0.669	0.331
M71 Other bursopathies	0.668	0.331
M42 Spinal osteochondrosis	0.668	0.332
M40 Kyphosis and lordosis	0.668	0.332
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.668	0.332
V10-V19 Pedal cyclist injured in transport accident	0.666	0.334
T79-T79 Certain early complications of trauma	0.666	0.334
D64 Other anaemias	0.666	0.334
I70 Atherosclerosis	0.665	0.335
I31 Other diseases of pericardium	0.665	0.335
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.664	0.336
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.663	0.337
D61 Other aplastic anaemias	0.663	0.337
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.663	0.337
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.663	0.337
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.663	0.337
T83.2 Mechanical complication of graft of urinary organ	0.663	0.337
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.663	0.337
E87.3 Alkalosis	0.661	0.339
S72 Fracture of femur	0.660	0.340
T84.2 Mechanical complication of internal fixation device of other bones	0.658	0.342
D67 Hereditary factor IX deficiency	0.658	0.342
D66 Hereditary factor VIII deficiency	0.658	0.342
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.658	0.342
E29.1 Testicular hypofunction	0.658	0.342
H33.2 Serous retinal detachment	0.658	0.342
S01 Open wound of head	0.658	0.342
M50 Cervical disk disorders	0.658	0.342
I69.3 Sequelae of cerebral infarction	0.656	0.344
S02.2 Fracture of nasal bones	0.656	0.344
H36.0 Diabetic retinopathy	0.654	0.346
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.653	0.347
Y35-Y36 Legal intervention and operations of war	0.653	0.347
Y10-Y34 Event of undetermined intent	0.653	0.347
Y00-Y09 Assault	0.653	0.347
X85-X99 Assault	0.653	0.347
X58-X59 Accidental exposure to other and unspecified factors	0.653	0.347
X50-X57 Overexertion, travel and privation	0.653	0.347
X40-X49 Accidental poisoning by and exposure to noxious substances	0.653	0.347
X30-X39 Exposure to forces of nature	0.653	0.347
X10-X19 Contact with heat and hot substances	0.653	0.347
X00-X09 Exposure to smoke, fire and flames	0.653	0.347
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.653	0.347
W75-W84 Other accidental threats to breathing	0.653	0.347
W65-W74 Accidental drowning and submersion	0.653	0.347
V98-V99 Other and unspecified transport accidents	0.653	0.347
V95-V97 Air and space transport accidents	0.653	0.347
V90-V94 Water transport accidents	0.653	0.347
V80-V89 Other land transport accidents	0.653	0.347
V70-V79 Bus occupant injured in transport accident	0.653	0.347
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.653	0.347
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.653	0.347
V40-V49 Car occupant injured in transport accident	0.653	0.347
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.653	0.347
V01-V09 Pedestrian injured in transport accident	0.653	0.347
H35.4 Peripheral retinal degeneration	0.652	0.348
S79 Other and unspecified injuries of hip and thigh	0.652	0.348
Q60-Q64 Congenital malformations of the urinary system	0.651	0.349
H43-H45 Disorders of vitreous body and globe	0.650	0.350
T74 Maltreatment syndromes	0.648	0.351
T73 Effects of other deprivation	0.648	0.351
T70 Effects of air pressure and water pressure	0.648	0.351
T69 Other effects of reduced temperature	0.648	0.351
T67 Effects of heat and light	0.648	0.351
T71 Asphyxiation	0.648	0.351
T66 Unspecified effects of radiation	0.648	0.351
W00-W19 Falls	0.646	0.354
S02.40 Fracture of malar and maxillary bones (closed)	0.645	0.355
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.645	0.355
E46 Unspecified protein-energy malnutrition	0.645	0.355
E87.1 Hypo-osmolality and hyponatraemia	0.645	0.355
E28 Ovarian dysfunction	0.644	0.356
I65.2 Occlusion and stenosis of carotid artery	0.644	0.356
M65.9 Synovitis and tenosynovitis, unspecified	0.644	0.356
E87.4 Mixed disorder of acid-base balance	0.643	0.357
Q38-Q45 Other congenital malformations of the digestive system	0.642	0.358
H46-H48 Disorders of optic nerve and visual pathways	0.642	0.358
T78.3 Angioneurotic oedema	0.642	0.358
M43.9 Deforming dorsopathy, unspecified	0.640	0.360
M43.8 Other specified deforming dorsopathies	0.640	0.360
M43.6 Torticollis	0.640	0.360
M43.5 Other recurrent vertebral subluxation	0.640	0.360
M43.4 Other recurrent atlantoaxial subluxation	0.640	0.360
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.640	0.360
M43.2 Other fusion of spine	0.640	0.360
V20-V29 Motorcycle rider injured in transport accident	0.639	0.360
M66 Spontaneous rupture of synovium and tendon	0.639	0.361
X60-X84 Intentional self-harm	0.639	0.361
S49 Other and unspecified injuries of shoulder and upper arm	0.638	0.362
S48 Traumatic amputation of shoulder and upper arm	0.638	0.362
S45 Injury of blood vessels at shoulder and upper arm level	0.638	0.362
S44 Injury of nerves at shoulder and upper arm level	0.638	0.362
S47 Crushing injury of shoulder and upper arm	0.638	0.362
S02.9 Fracture of skull and facial bones, part unspecified	0.638	0.362
S02.7 Multiple fractures involving skull and facial bones	0.638	0.362
S02.5 Fracture of tooth	0.638	0.362
S02.0 Fracture of vault of skull	0.638	0.362
I05.8 Other mitral valve diseases	0.637	0.363
I05.2 Mitral stenosis with insufficiency	0.637	0.363
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.637	0.363
T92 Sequelae of injuries of upper limb	0.636	0.364
D58 Other hereditary haemolytic anaemias	0.636	0.364
E66 Obesity	0.636	0.364
I47 Paroxysmal tachycardia	0.635	0.365
I67 Other cerebrovascular diseases	0.635	0.365
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.634	0.366
J33.9 Nasal polyp, unspecified	0.634	0.366
S27 Injury of other and unspecified intrathoracic organs	0.634	0.366
M92 Other juvenile osteochondrosis	0.633	0.367
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.633	0.367
S02.80 Fractures of other skull and facial bones (closed)	0.632	0.368
I20 Angina pectoris	0.632	0.368
I34.8 Other nonrheumatic mitral valve disorders	0.631	0.369
I34.2 Nonrheumatic mitral (valve) stenosis	0.631	0.369
I51.9 Heart disease, unspecified	0.630	0.369
T84.0 Mechanical complication of internal joint prosthesis	0.629	0.371
I15 Secondary hypertension	0.629	0.371
I13 Hypertensive heart and renal disease	0.629	0.371
I11 Hypertensive heart disease	0.629	0.371
M80-M85 Disorders of bone density and structure	0.628	0.371
S05.8 Other injuries of eye and orbit	0.628	0.372
I63.8 Other cerebral infarction	0.628	0.372
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.628	0.372
E04 Other non-toxic goitre	0.628	0.372
I07 Rheumatic tricuspid valve diseases	0.626	0.374
M06 Other rheumatoid arthritis	0.626	0.374
I69.1 Sequelae of intracerebral haemorrhage	0.624	0.376
M76 Enthesopathies of lower limb, excluding foot	0.623	0.377
M73 Soft tissue disorders in diseases classified elsewhere	0.623	0.377
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.622	0.378
Y84.6 Urinary catheterisation	0.622	0.378
M87 Osteonecrosis	0.621	0.378
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.621	0.379
H11 Other disorders of conjunctiva	0.621	0.379
E05.8 Other thyrotoxicosis	0.620	0.379
E05.5 Thyroid crisis or storm	0.620	0.379
E05.4 Thyrotoxicosis factitia	0.620	0.379
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.620	0.379
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.620	0.379
S78 Traumatic amputation of hip and thigh	0.619	0.380
S77 Crushing injury of hip and thigh	0.619	0.380
S76 Injury of muscle and tendon at hip and thigh level	0.619	0.380
S75 Injury of blood vessels at hip and thigh level	0.619	0.380
S74 Injury of nerves at hip and thigh level	0.619	0.380
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.619	0.380
H55-H59 Other disorders of eye and adnexa	0.616	0.384
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.616	0.384
Q35-Q37 Cleft lip and cleft palate	0.616	0.384
Q30-Q34 Congenital malformations of the respiratory system	0.616	0.384
S42 Fracture of shoulder and upper arm	0.616	0.384
M48.02 Spinal stenosis (Cervical region)	0.616	0.384
I25.5 Ischaemic cardiomyopathy	0.615	0.384
J40 Bronchitis, not specified as acute or chronic	0.615	0.385
S02.6 Fracture of mandible	0.615	0.385
I62 Other nontraumatic intracranial haemorrhage	0.615	0.385
M43.19 Spondylolisthesis (Site unspecified)	0.614	0.386
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.614	0.386
M43.15 Spondylolisthesis (Thoracolumbar region)	0.614	0.386
M43.14 Spondylolisthesis (Thoracic region)	0.614	0.386
M43.13 Spondylolisthesis (Cervicothoracic region)	0.614	0.386
M43.12 Spondylolisthesis (Cervical region)	0.614	0.386
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.614	0.386
M43.10 Spondylolisthesis (Multiple sites in spine)	0.614	0.386
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.614	0.386
I69.0 Sequelae of subarachnoid haemorrhage	0.614	0.386
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.613	0.387
E21.3 Hyperparathyroidism, unspecified	0.613	0.387
I72 Other aneurysm	0.613	0.387
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.612	0.388
M86 Osteomyelitis	0.611	0.388
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.611	0.389
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.611	0.389
M49 Spondylopathies in diseases classified elsewhere	0.610	0.390
Q00-Q07 Congenital malformations of the nervous system	0.607	0.393
D69.9 Haemorrhagic condition, unspecified	0.607	0.393
D69.8 Other specified haemorrhagic conditions	0.607	0.393
D69.5 Secondary thrombocytopenia	0.607	0.393
D69.4 Other primary thrombocytopenia	0.607	0.393
D69.2 Other nonthrombocytopenic purpura	0.607	0.393
D69.1 Qualitative platelet defects	0.607	0.393
D69.0 Allergic purpura	0.607	0.393
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.606	0.394
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.606	0.394
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.606	0.394
Y60-Y69 Misadventures to patients during surgical and medical care	0.605	0.395
M72 Fibroblastic disorders	0.603	0.397
W20-W49 Exposure to inanimate mechanical forces	0.602	0.398
S50-S59 Injuries to the elbow and forearm	0.602	0.398
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.602	0.398
Y83.5 Amputation of limb(s)	0.602	0.398
T15-T19 Effects of foreign body entering through natural orifice	0.601	0.399
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.601	0.399
T83.3 Mechanical complication of intra-uterine contraceptive device	0.601	0.399
I95-I99 Other and unspecified disorders of the circulatory system	0.601	0.399
D80.1 Nonfamilial hypogammaglobulinaemia	0.599	0.401
B25-B34 Other viral diseases	0.599	0.401
S22.0 Fracture of thoracic vertebra	0.599	0.401
Chapter VI Diseases of the nervous system	0.599	0.401
S10 Superficial injury of neck	0.598	0.401
E11 Non-insulin-dependent diabetes mellitus	0.598	0.402
S29 Other and unspecified injuries of thorax	0.597	0.403

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations