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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79512063
log Bayes Factor = 24.6388
Chromosome 8   position 89,533,747  (GRCh37) Explore rs79512063 on Ensembl!
Variant rs79512063 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.991 0.009 0.000
K22 Other diseases of oesophagus
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.983 0.017 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
I20 Angina pectoris
0.979 0.021 0.000
T39.1 4-Aminophenol derivatives
0.978 0.022 0.000
K31 Other diseases of stomach and duodenum
0.978 0.022 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.975 0.025 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.975 0.025 0.000
K25 Gastric ulcer
0.974 0.026 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.970 0.030 0.000
K20 Oesophagitis
0.968 0.032 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
I60-I69 Cerebrovascular diseases
0.965 0.035 0.000
I20.9 Angina pectoris, unspecified
0.965 0.035 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.959 0.041 0.000
Z50 Care involving use of rehabilitation procedures
0.959 0.041 0.000
M20-M25 Other joint disorders
0.957 0.043 0.000
K31.7 Polyp of stomach and duodenum
0.956 0.044 0.000
D50-D53 Nutritional anaemias
0.955 0.045 0.000
K90-K93 Other diseases of the digestive system
0.955 0.045 0.000
M80-M85 Disorders of bone density and structure
0.952 0.048 0.000
K30 Dyspepsia
0.951 0.049 0.000
H04 Disorders of lachrymal system
0.950 0.050 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.948 0.052 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.948 0.052 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.945 0.055 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.933 0.067 0.000
H04.2 Epiphora
0.931 0.069 0.000
K92 Other diseases of digestive system
0.930 0.070 0.000
I63 Cerebral infarction
0.927 0.073 0.000
I71 Aortic aneurysm and dissection
0.926 0.074 0.000
Z50.1 Other physical therapy
0.924 0.076 0.000
S60-S69 Injuries to the wrist and hand
0.920 0.080 0.000
B35-B49 Mycoses
0.919 0.081 0.000
Z60 Problems related to social environment
0.918 0.082 0.000
K22.2 Oesophageal obstruction
0.917 0.083 0.000
K26 Duodenal ulcer
0.917 0.083 0.000
M81 Osteoporosis without pathological fracture
0.917 0.083 0.000
M15-M19 Arthrosis
0.915 0.085 0.000
M47 Spondylosis
0.908 0.092 0.000
A00-A09 Intestinal infectious diseases
0.908 0.092 0.000
D50 Iron deficiency anaemia
0.908 0.092 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.908 0.092 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.906 0.094 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.906 0.094 0.000
I63.9 Cerebral infarction, unspecified
0.904 0.096 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.898 0.102 0.000
S00-S09 Injuries to the head
0.897 0.103 0.000
K22.1 Ulcer of oesophagus
0.893 0.107 0.000
Z60.2 Living alone
0.888 0.112 0.000
M19 Other arthrosis
0.884 0.116 0.000
S20-S29 Injuries to the thorax
0.882 0.118 0.000
Z04 Examination and observation for other reasons
0.881 0.119 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.881 0.119 0.000
I21 Acute myocardial infarction
0.880 0.120 0.000
E70-E90 Metabolic disorders
0.876 0.124 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.875 0.125 0.000
M81.9 Osteoporosis, unspecified
0.874 0.126 0.000
B37 Candidiasis
0.873 0.127 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.873 0.127 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.871 0.129 0.000
R50-R69 General symptoms and signs
0.871 0.129 0.000
K22.7 Barrett's oesophagus
0.868 0.132 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.868 0.132 0.000
I25.2 Old myocardial infarction
0.867 0.133 0.000
H53-H54 Visual disturbances and blindness
0.866 0.134 0.000
K92.1 Melaena
0.864 0.136 0.000
S80-S89 Injuries to the knee and lower leg
0.863 0.137 0.000
D50.8 Other iron deficiency anaemias
0.861 0.139 0.000
K22.4 Dyskinesia of oesophagus
0.860 0.140 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.858 0.142 0.000
M19.9 Arthrosis, unspecified
0.857 0.143 0.000
I77 Other disorders of arteries and arterioles
0.854 0.146 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.854 0.146 0.000
H30-H36 Disorders of choroid and retina
0.853 0.147 0.000
Z13 Special screening examination for other diseases and disorders
0.851 0.149 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.850 0.150 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.850 0.150 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.850 0.150 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.847 0.153 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.847 0.153 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.847 0.153 0.000
B37.0 Candidal stomatitis
0.846 0.154 0.000
H10-H13 Disorders of conjunctiva
0.844 0.156 0.000
D51 Vitamin B12 deficiency anaemia
0.844 0.156 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.843 0.157 0.000
R13 Dysphagia
0.843 0.157 0.000
I72 Other aneurysm
0.839 0.161 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.838 0.162 0.000
K50-K52 Noninfective enteritis and colitis
0.838 0.162 0.000
M25 Other joint disorders, not elsewhere classified
0.837 0.163 0.000
M47.8 Other spondylosis
0.835 0.165 0.000
E87.2 Acidosis
0.833 0.167 0.000
Chapter XX External causes of morbidity and mortality
0.831 0.169 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.831 0.169 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.828 0.172 0.000
K55-K64 Other diseases of intestines
0.828 0.172 0.000
I73 Other peripheral vascular diseases
0.825 0.175 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.824 0.176 0.000
I25.1 Atherosclerotic heart disease
0.823 0.177 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.821 0.179 0.000
Z50.8 Care involving use of rehabilitation procedures
0.821 0.179 0.000
A04 Other bacterial intestinal infections
0.821 0.179 0.000
M23 Internal derangement of knee
0.820 0.180 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.815 0.185 0.000
M40-M43 Deforming dorsopathies
0.812 0.188 0.000
K92.0 Haematemesis
0.811 0.189 0.000
I69 Sequelae of cerebrovascular disease
0.810 0.190 0.000
E20-E35 Disorders of other endocrine glands
0.810 0.190 0.000
K22.9 Disease of oesophagus, unspecified
0.809 0.191 0.000
Z48 Other surgical follow-up care
0.808 0.192 0.000
M35 Other systemic involvement of connective tissue
0.808 0.192 0.000
S64 Injury of nerves at wrist and hand level
0.806 0.194 0.000
B95-B98 Bacterial, viral and other infectious agents
0.804 0.196 0.000
Chapter XXII Codes for special purposes
0.802 0.198 0.000
Chapter V Mental and behavioural disorders
0.799 0.201 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.799 0.201 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.797 0.203 0.000
K25.4 Chronic or unspecified with haemorrhage
0.797 0.203 0.000
M31 Other necrotising vasculopathies
0.795 0.205 0.000
T43.2 Other and unspecified antidepressants
0.794 0.206 0.000
K70-K77 Diseases of liver
0.793 0.207 0.000
A30-A49 Other bacterial diseases
0.793 0.207 0.000
T39.0 Salicylates
0.792 0.208 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.792 0.208 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.791 0.209 0.000
M45 Ankylosing spondylitis
0.791 0.209 0.000
S00 Superficial injury of head
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.789 0.211 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.789 0.211 0.000
Z50.5 Speech therapy
0.788 0.212 0.000
S90-S99 Injuries to the ankle and foot
0.786 0.214 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.785 0.215 0.000
E10-E14 Diabetes mellitus
0.784 0.216 0.000
H05 Disorders of orbit
0.783 0.217 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.783 0.217 0.000
K35-K38 Diseases of appendix
0.781 0.219 0.000
R51 Headache
0.780 0.220 0.000
R59 Enlarged lymph nodes
0.779 0.221 0.000
H04.1 Other disorders of lachrymal gland
0.779 0.221 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.779 0.221 0.000
H55-H59 Other disorders of eye and adnexa
0.776 0.224 0.000
K55 Vascular disorders of intestine
0.774 0.225 0.000
M24 Other specific joint derangements
0.774 0.226 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.774 0.226 0.000
R63 Symptoms and signs concerning food and fluid intake
0.773 0.227 0.000
S40-S49 Injuries to the shoulder and upper arm
0.773 0.227 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.773 0.227 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.772 0.228 0.000
Z04.3 Examination and observation following other accident
0.772 0.228 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.771 0.229 0.000
Z04.9 Examination and observation for unspecified reason
0.771 0.229 0.000
K58 Irritable bowel syndrome
0.771 0.229 0.000
Z02 Examination and encounter for administrative purposes
0.770 0.230 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.770 0.230 0.000
M48 Other spondylopathies
0.769 0.231 0.000
Chapter VI Diseases of the nervous system
0.768 0.232 0.000
M47.86 Other spondylosis (Lumbar region)
0.766 0.234 0.000
M81.4 Drug-induced osteoporosis
0.764 0.236 0.000
K51 Ulcerative colitis
0.762 0.238 0.000
R18 Ascites
0.761 0.239 0.000
D55-D59 Haemolytic anaemias
0.761 0.239 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.761 0.239 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.758 0.242 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.758 0.242 0.000
Z63 Other problems related to primary support group, including family circumstances
0.757 0.243 0.000
Chapter VIII Diseases of the ear and mastoid process
0.757 0.243 0.000
Z43 Attention to artificial openings
0.754 0.246 0.000
M86-M90 Other osteopathies
0.752 0.248 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.750 0.250 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.750 0.250 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.750 0.250 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.749 0.251 0.000
M47.9 Spondylosis, unspecified
0.749 0.251 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.747 0.253 0.000
E50-E64 Other nutritional deficiencies
0.747 0.253 0.000
M23.3 Other meniscus derangements
0.747 0.253 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.747 0.253 0.000
H35 Other retinal disorders
0.746 0.254 0.000
I60 Subarachnoid haemorrhage
0.745 0.255 0.000
I21.4 Acute subendocardial myocardial infarction
0.745 0.255 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.745 0.255 0.000
Z52 Donors of organs and tissues
0.744 0.256 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.744 0.256 0.000
M25.5 Pain in joint
0.743 0.257 0.000
M46 Other inflammatory spondylopathies
0.741 0.259 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.739 0.261 0.000
H43-H45 Disorders of vitreous body and globe
0.738 0.261 0.000
I62 Other nontraumatic intracranial haemorrhage
0.738 0.262 0.000
S06 Intracranial injury
0.737 0.263 0.000
S82 Fracture of lower leg, including ankle
0.737 0.263 0.000
I21.9 Acute myocardial infarction, unspecified
0.737 0.263 0.000
R54 Senility
0.737 0.263 0.000
R57 Shock, not elsewhere classified
0.735 0.265 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.735 0.265 0.000
I72.4 Aneurysm of artery of lower extremity
0.735 0.265 0.000
D60-D64 Aplastic and other anaemias
0.735 0.265 0.000
I20.0 Unstable angina
0.734 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.734 0.266 0.000
O42 Premature rupture of membranes
0.733 0.266 0.000
E88 Other metabolic disorders
0.732 0.268 0.000
H54 Blindness and low vision
0.730 0.270 0.000
Z73 Problems related to life-management difficulty
0.729 0.271 0.000
I70 Atherosclerosis
0.728 0.271 0.000
K40-K46 Hernia
0.728 0.272 0.000
I77.1 Stricture of artery
0.726 0.274 0.000
D70 Agranulocytosis
0.724 0.276 0.000
S64.4 Injury of digital nerve of other finger
0.724 0.276 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.724 0.276 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.723 0.277 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.723 0.277 0.000
R15 Faecal incontinence
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.722 0.278 0.000
Chapter II Neoplasms
0.722 0.278 0.000
E00-E07 Disorders of thyroid gland
0.721 0.279 0.000
I74 Arterial embolism and thrombosis
0.719 0.281 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K27 Peptic ulcer, site unspecified
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I20.1 Angina pectoris with documented spasm
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.716 0.284 0.000
Z57 Occupational exposure to risk-factors
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
M22 Disorders of patella
0.715 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.284 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.284 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.715 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.284 0.000
T36 Poisoning by systemic antibiotics
0.715 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.715 0.285 0.000
I61 Intracerebral haemorrhage
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
M35.3 Polymyalgia rheumatica
0.714 0.286 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.714 0.286 0.000
A08 Viral and other specified intestinal infections
0.713 0.287 0.000
K31.8 Other specified diseases of stomach and duodenum
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.712 0.288 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.712 0.288 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.711 0.289 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.711 0.289 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.711 0.289 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.711 0.289 0.000
T39.4 Antirheumatics, not elsewhere classified
0.711 0.289 0.000
T39.2 Pyrazolone derivatives
0.711 0.289 0.000
K22.5 Diverticulum of oesophagus, acquired
0.711 0.289 0.000
K22.3 Perforation of oesophagus
0.711 0.289 0.000
K22.0 Achalasia of cardia
0.711 0.289 0.000
I24 Other acute ischaemic heart diseases
0.710 0.289 0.000
I22 Subsequent myocardial infarction
0.710 0.290 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.709 0.291 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.709 0.291 0.000
R58 Haemorrhage, not elsewhere classified
0.708 0.292 0.000
K26.3 Acute without haemorrhage or perforation
0.708 0.292 0.000
S01 Open wound of head
0.707 0.293 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
I73.0 Raynaud's syndrome
0.707 0.293 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.707 0.293 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.706 0.294 0.000
H10 Conjunctivitis
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.295 0.000
K25.3 Acute without haemorrhage or perforation
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
B65-B83 Helminthiases
0.704 0.296 0.000
B50-B64 Protozoal diseases
0.704 0.296 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.704 0.296 0.000
B15-B19 Viral hepatitis
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A65-A69 Other spirochaetal diseases
0.704 0.296 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
A15-A19 Tuberculosis
0.704 0.296 0.000
K65-K67 Diseases of peritoneum
0.702 0.298 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.702 0.298 0.000
H53 Visual disturbances
0.701 0.298 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.701 0.299 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.701 0.299 0.000
K31.6 Fistula of stomach and duodenum
0.701 0.299 0.000
K31.5 Obstruction of duodenum
0.701 0.299 0.000
K31.4 Gastric diverticulum
0.701 0.299 0.000
K31.3 Pylorospasm, not elsewhere classified
0.701 0.299 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.701 0.299 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.701 0.299 0.000
K31.0 Acute dilatation of stomach
0.701 0.299 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.699 0.301 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.699 0.301 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.699 0.301 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.699 0.301 0.000
H00 Hordeolum and chalazion
0.699 0.301 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.699 0.301 0.000
Z10 Routine general health check-up of defined subpopulation
0.699 0.301 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.698 0.301 0.000
K51.9 Ulcerative colitis, unspecified
0.699 0.301 0.000
K25.7 Chronic without haemorrhage or perforation
0.698 0.302 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.698 0.302 0.000
K25.5 Chronic or unspecified with perforation
0.698 0.302 0.000
K25.2 Acute with both haemorrhage and perforation
0.698 0.302 0.000
K25.1 Acute with perforation
0.698 0.302 0.000
K25.0 Acute with haemorrhage
0.698 0.302 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.698 0.302 0.000
M80 Osteoporosis with pathological fracture
0.696 0.303 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.695 0.305 0.000
S61 Open wound of wrist and hand
0.695 0.305 0.000
M49 Spondylopathies in diseases classified elsewhere
0.694 0.306 0.000
Z75 Problems related to medical facilities and other health care
0.692 0.308 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
F30-F39 Mood [affective] disorders
0.692 0.308 0.000
S62 Fracture at wrist and hand level
0.692 0.308 0.000
M21 Other acquired deformities of limbs
0.691 0.309 0.000
T82.3 Mechanical complication of other vascular grafts
0.691 0.309 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.689 0.311 0.000
Z65 Problems related to other psychosocial circumstances
0.688 0.312 0.000
Z64 Problems related to certain psychosocial circumstances
0.688 0.312 0.000
Z62 Other problems related to upbringing
0.688 0.312 0.000
Z61 Problems related to negative life events in childhood
0.688 0.312 0.000
Z59 Problems related to housing and economic circumstances
0.688 0.312 0.000
Z58 Problems related to physical environment
0.688 0.312 0.000
Z56 Problems related to employment and unemployment
0.688 0.312 0.000
Z55 Problems related to education and literacy
0.688 0.312 0.000
E40-E46 Malnutrition
0.688 0.312 0.000
Z54 Convalescence
0.688 0.312 0.000
Z49 Care involving dialysis
0.688 0.312 0.000
Z44 Fitting and adjustment of external prosthetic device
0.688 0.312 0.000
S02 Fracture of skull and facial bones
0.688 0.312 0.000
Z50.6 Orthoptic training
0.687 0.312 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.687 0.312 0.000
Z50.3 Drug rehabilitation
0.687 0.312 0.000
Z50.2 Alcohol rehabilitation
0.687 0.312 0.000
S27 Injury of other and unspecified intrathoracic organs
0.687 0.313 0.000
S00.8 Superficial injury of other parts of head
0.687 0.313 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.314 0.000
M34 Systemic sclerosis
0.686 0.314 0.000
M33 Dermatopolymyositis
0.686 0.314 0.000
M32 Systemic lupus erythematosus
0.686 0.314 0.000
M30 Polyarteritis nodosa and related conditions
0.686 0.314 0.000
T90 Sequelae of injuries of head
0.686 0.314 0.000
Z48.0 Attention to surgical dressings and sutures
0.686 0.314 0.000
D53 Other nutritional anaemias
0.685 0.315 0.000
D52 Folate deficiency anaemia
0.685 0.315 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.684 0.315 0.000
B37.3 Candidiasis of vulva and vagina
0.684 0.316 0.000
M50-M54 Other dorsopathies
0.684 0.316 0.000
M85 Other disorders of bone density and structure
0.683 0.317 0.000
M84 Disorders of continuity of bone
0.683 0.317 0.000
M83 Adult osteomalacia
0.683 0.317 0.000
M82 Osteoporosis in diseases classified elsewhere
0.683 0.317 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.682 0.318 0.000
H04.9 Disorder of lachrymal system, unspecified
0.681 0.318 0.000
H04.8 Other disorders of lachrymal system
0.681 0.318 0.000
H04.6 Other changes in lachrymal passages
0.681 0.318 0.000
H04.4 Chronic inflammation of lachrymal passages
0.681 0.318 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.681 0.318 0.000
H04.0 Dacryoadenitis
0.681 0.318 0.000
E22 Hyperfunction of pituitary gland
0.681 0.319 0.000
M19.0 Primary arthrosis of other joints
0.681 0.319 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.681 0.319 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.680 0.320 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.680 0.320 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.680 0.320 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.679 0.320 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.679 0.320 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.679 0.320 0.000
T85.2 Mechanical complication of intraocular lens
0.679 0.320 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.679 0.320 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.679 0.320 0.000
M31.6 Other giant cell arteritis
0.679 0.321 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.677 0.323 0.000
E83 Disorders of mineral metabolism
0.677 0.323 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.676 0.324 0.000
M43 Other deforming dorsopathies
0.675 0.325 0.000
T91 Sequelae of injuries of neck and trunk
0.675 0.325 0.000
D80-D89 Certain disorders involving the immune mechanism
0.674 0.326 0.000
S22.3 Fracture of rib
0.673 0.327 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.673 0.327 0.000
Z00.0 General medical examination
0.673 0.327 0.000
D50.9 Iron deficiency anaemia, unspecified
0.672 0.328 0.000
K55.0 Acute vascular disorders of intestine
0.672 0.328 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.670 0.330 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.669 0.330 0.000
Z74 Problems related to care-provider dependency
0.669 0.331 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.669 0.331 0.000
H01 Other inflammation of eyelid
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.668 0.332 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.668 0.332 0.000
E11 Non-insulin-dependent diabetes mellitus
0.668 0.332 0.000
K92.9 Disease of digestive system, unspecified
0.667 0.333 0.000
K92.8 Other specified diseases of digestive system
0.667 0.333 0.000
M47.2 Other spondylosis with radiculopathy
0.666 0.334 0.000
O80-O84 Delivery
0.665 0.335 0.000
I63.8 Other cerebral infarction
0.665 0.335 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.665 0.335 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.665 0.335 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.665 0.335 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.665 0.335 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.665 0.335 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.665 0.335 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.664 0.336 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.664 0.336 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.664 0.336 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.664 0.336 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.664 0.336 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.664 0.336 0.000
I71.0 Dissection of aorta [any part]
0.664 0.336 0.000
T81 Complications of procedures, not elsewhere classified
0.663 0.337 0.000
S81 Open wound of lower leg
0.662 0.337 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.662 0.338 0.000
R63.4 Abnormal weight loss
0.662 0.338 0.000
S00.9 Superficial injury of head, part unspecified
0.662 0.338 0.000
R12 Heartburn
0.661 0.339 0.000
H11 Other disorders of conjunctiva
0.661 0.339 0.000
S69 Other and unspecified injuries of wrist and hand
0.660 0.340 0.000
S68 Traumatic amputation of wrist and hand
0.660 0.340 0.000
S67 Crushing injury of wrist and hand
0.660 0.340 0.000
S65 Injury of blood vessels at wrist and hand level
0.660 0.340 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.660 0.340 0.000
S60 Superficial injury of wrist and hand
0.660 0.340 0.000
M16 Coxarthrosis [arthrosis of hip]
0.660 0.340 0.000
B48 Other mycoses, not elsewhere classified
0.659 0.341 0.000
B47 Mycetoma
0.659 0.341 0.000
B46 Zygomycosis
0.659 0.341 0.000
B45 Cryptococcosis
0.659 0.341 0.000
B44 Aspergillosis
0.659 0.341 0.000
B43 Chromomycosis and phaeomycotic abscess
0.659 0.341 0.000
B42 Sporotrichosis
0.659 0.341 0.000
B41 Paracoccidioidomycosis
0.659 0.341 0.000
B40 Blastomycosis
0.659 0.341 0.000
B39 Histoplasmosis
0.659 0.341 0.000
B38 Coccidioidomycosis
0.659 0.341 0.000
B36 Other superficial mycoses
0.659 0.341 0.000
B35 Dermatophytosis
0.659 0.341 0.000
B49 Unspecified mycosis
0.659 0.341 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.659 0.341 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.659 0.341 0.000
Z60.9 Problem related to social environment, unspecified
0.658 0.342 0.000
Z60.8 Other problems related to social environment
0.658 0.342 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.658 0.342 0.000
Z60.4 Social exclusion and rejection
0.658 0.342 0.000
Z60.3 Acculturation difficulty
0.658 0.342 0.000
Z60.1 Atypical parenting situation
0.658 0.342 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
H65-H75 Diseases of middle ear and mastoid
0.658 0.342 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.658 0.342 0.000
K26.5 Chronic or unspecified with perforation
0.658 0.342 0.000
K26.4 Chronic or unspecified with haemorrhage
0.658 0.342 0.000
K26.2 Acute with both haemorrhage and perforation
0.658 0.342 0.000
K26.1 Acute with perforation
0.658 0.342 0.000
K26.0 Acute with haemorrhage
0.658 0.342 0.000
M81.8 Other osteoporosis
0.657 0.342 0.000
M81.6 Localised osteoporosis [Lequesne]
0.657 0.342 0.000
M81.5 Idiopathic osteoporosis
0.657 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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