TreeWAS – Variant ID: rs79567137

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
K76 Other diseases of liver	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
K70-K77 Diseases of liver	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
K76.8 Other specified diseases of liver	0.998	0.002
Chapter IX Diseases of the circulatory system	0.997	0.003
K76.0 Fatty (change of) liver, not elsewhere classified	0.995	0.005
S00-S09 Injuries to the head	0.989	0.011
Chapter XIV Diseases of the genitourinary system	0.987	0.013
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.986	0.014
K50-K52 Noninfective enteritis and colitis	0.982	0.018
Chapter VII Diseases of the eye and adnexa	0.982	0.018
N10-N16 Renal tubulo-interstitial diseases	0.982	0.018
K35-K38 Diseases of appendix	0.981	0.019
I60-I69 Cerebrovascular diseases	0.980	0.020
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.975	0.025
N17-N19 Renal failure	0.969	0.031
K51 Ulcerative colitis	0.961	0.039
S00 Superficial injury of head	0.959	0.041
N13 Obstructive and reflux uropathy	0.956	0.044
Chapter IV Endocrine, nutritional and metabolic diseases	0.956	0.044
N19 Unspecified renal failure	0.955	0.045
T85 Complications of other internal prosthetic devices, implants and grafts	0.953	0.047
K35 Acute appendicitis	0.951	0.049
K51.9 Ulcerative colitis, unspecified	0.950	0.050
T36-T50 Poisoning by drugs, medicaments and biological substances	0.948	0.052
Chapter VIII Diseases of the ear and mastoid process	0.944	0.056
I70-I79 Diseases of arteries, arterioles and capillaries	0.940	0.060
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.938	0.062
Chapter XX External causes of morbidity and mortality	0.935	0.065
I69 Sequelae of cerebrovascular disease	0.934	0.066
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.921	0.079
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.920	0.080
E65-E68 Obesity and other hyperalimentation	0.911	0.089
I95-I99 Other and unspecified disorders of the circulatory system	0.909	0.091
Chapter VI Diseases of the nervous system	0.902	0.098
N13.3 Other and unspecified hydronephrosis	0.901	0.099
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.901	0.099
K35.9 Acute appendicitis, unspecified	0.895	0.105
E10-E14 Diabetes mellitus	0.889	0.111
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.886	0.114
I63 Cerebral infarction	0.885	0.115
H80-H83 Diseases of inner ear	0.881	0.119
E66 Obesity	0.880	0.120
H52 Disorders of refraction and accommodation	0.880	0.120
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.876	0.124
K50 Crohn's disease [regional enteritis]	0.874	0.126
K37 Unspecified appendicitis	0.868	0.132
S02 Fracture of skull and facial bones	0.865	0.135
H30-H36 Disorders of choroid and retina	0.864	0.136
E66.8 Other obesity	0.863	0.137
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.863	0.137
G90-G99 Other disorders of the nervous system	0.861	0.139
I74 Arterial embolism and thrombosis	0.859	0.141
Q20-Q28 Congenital malformations of the circulatory system	0.858	0.142
N13.8 Other obstructive and reflux uropathy	0.856	0.144
I86 Varicose veins of other sites	0.853	0.147
I85 Oesophageal varices	0.848	0.152
H80 Otosclerosis	0.845	0.155
I95 Hypotension	0.845	0.155
I72 Other aneurysm	0.841	0.159
K74 Fibrosis and cirrhosis of liver	0.840	0.159
T85.4 Mechanical complication of breast prosthesis and implant	0.840	0.160
G91 Hydrocephalus	0.839	0.161
I67 Other cerebrovascular diseases	0.838	0.162
H46-H48 Disorders of optic nerve and visual pathways	0.837	0.163
S00.0 Superficial injury of scalp	0.836	0.164
H55-H59 Other disorders of eye and adnexa	0.833	0.167
S05 Injury of eye and orbit	0.832	0.168
Y60-Y69 Misadventures to patients during surgical and medical care	0.832	0.168
S09 Other and unspecified injuries of head	0.831	0.169
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.831	0.169
N13.5 Kinking and stricture of ureter without hydronephrosis	0.830	0.170
S00.3 Superficial injury of nose	0.830	0.170
N40-N51 Diseases of male genital organs	0.827	0.173
N25-N29 Other disorders of kidney and ureter	0.826	0.174
T80 Complications following infusion, transfusion and therapeutic injection	0.826	0.174
G91.9 Hydrocephalus, unspecified	0.824	0.176
S90-S99 Injuries to the ankle and foot	0.823	0.177
Q80-Q89 Other congenital malformations	0.821	0.178
H80.9 Otosclerosis, unspecified	0.820	0.180
E10 Insulin-dependent diabetes mellitus	0.819	0.181
Q60-Q64 Congenital malformations of the urinary system	0.818	0.182
H52.1 Myopia	0.818	0.182
K76.9 Liver disease, unspecified	0.815	0.185
H53-H54 Visual disturbances and blindness	0.811	0.189
K50.1 Crohn's disease of large intestine	0.810	0.190
S00.2 Other superficial injuries of eyelid and periocular area	0.809	0.191
K35.3 Acute appendicitis with localized peritonitis	0.808	0.192
I95.1 Orthostatic hypotension	0.808	0.192
I89.0 Lymphoedema, not elsewhere classified	0.806	0.194
H60-H62 Diseases of external ear	0.805	0.195
H43-H45 Disorders of vitreous body and globe	0.801	0.199
I60 Subarachnoid haemorrhage	0.800	0.200
I77 Other disorders of arteries and arterioles	0.798	0.202
Q00-Q07 Congenital malformations of the nervous system	0.797	0.203
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.795	0.205
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.795	0.205
S60-S69 Injuries to the wrist and hand	0.794	0.206
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.792	0.208
T91 Sequelae of injuries of neck and trunk	0.788	0.212
I69.0 Sequelae of subarachnoid haemorrhage	0.787	0.213
I73 Other peripheral vascular diseases	0.787	0.213
T20-T25 Burns and corrosions of external body surface, specified by site	0.784	0.216
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.781	0.218
K73 Chronic hepatitis, not elsewhere classified	0.781	0.219
Q50-Q56 Congenital malformations of genital organs	0.779	0.220
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.778	0.222
K35.2 Acute appendicitis with generalized peritonitis	0.778	0.222
N18 Chronic renal failure	0.778	0.222
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.777	0.223
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.777	0.223
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.774	0.226
T88 Other complications of surgical and medical care, not elsewhere classified	0.772	0.228
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.771	0.229
S50-S59 Injuries to the elbow and forearm	0.769	0.231
Q21 Congenital malformations of cardiac septa	0.769	0.231
K51.8 Other ulcerative colitis	0.768	0.232
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.768	0.232
K35.1 Acute appendicitis with peritoneal abscess	0.767	0.233
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.766	0.234
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.765	0.235
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.763	0.237
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.763	0.237
I63.8 Other cerebral infarction	0.760	0.240
S00.9 Superficial injury of head, part unspecified	0.758	0.242
S02.2 Fracture of nasal bones	0.757	0.243
T93 Sequelae of injuries of lower limb	0.754	0.246
S10-S19 Injuries to the neck	0.753	0.247
I62 Other nontraumatic intracranial haemorrhage	0.752	0.247
I67.8 Other specified cerebrovascular diseases	0.752	0.248
E10.9 Without complications	0.752	0.248
N00-N08 Glomerular diseases	0.752	0.248
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.751	0.249
S06 Intracranial injury	0.751	0.249
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.750	0.250
I86.4 Gastric varices	0.749	0.251
T87 Complications peculiar to reattachment and amputation	0.749	0.251
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.748	0.252
G80-G83 Cerebral palsy and other paralytic syndromes	0.748	0.252
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.747	0.253
E11 Non-insulin-dependent diabetes mellitus	0.747	0.253
Chapter X Diseases of the respiratory system	0.744	0.256
H35 Other retinal disorders	0.744	0.256
I73.0 Raynaud's syndrome	0.743	0.257
Chapter XXII Codes for special purposes	0.740	0.260
I69.3 Sequelae of cerebral infarction	0.738	0.262
G70-G73 Diseases of myoneural junction and muscle	0.737	0.262
I85.0 Oesophageal varices with bleeding	0.736	0.264
T79-T79 Certain early complications of trauma	0.736	0.264
I85.9 Oesophageal varices without bleeding	0.736	0.264
H52.0 Hypermetropia	0.736	0.264
K76.6 Portal hypertension	0.735	0.265
N10 Acute tubulo-interstitial nephritis	0.734	0.266
I86.8 Varicose veins of other specified sites	0.732	0.268
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.729	0.271
I69.1 Sequelae of intracerebral haemorrhage	0.728	0.272
G96 Other disorders of central nervous system	0.727	0.272
I63.9 Cerebral infarction, unspecified	0.727	0.273
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.726	0.274
H57 Other disorders of eye and adnexa	0.725	0.275
K51.2 Ulcerative (chronic) proctitis	0.724	0.276
W50-W64 Exposure to animate mechanical forces	0.723	0.277
H50 Other strabismus	0.723	0.277
T36 Poisoning by systemic antibiotics	0.719	0.281
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.719	0.281
H10-H13 Disorders of conjunctiva	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
K76.7 Hepatorenal syndrome	0.717	0.283
K76.5 Hepatic veno-occlusive disease	0.717	0.283
K76.4 Peliosis hepatis	0.717	0.283
K76.3 Infarction of liver	0.717	0.283
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283
K76.1 Chronic passive congestion of liver	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
K77 Liver disorders in diseases classified elsewhere	0.717	0.283
K71 Toxic liver disease	0.717	0.283
K72 Hepatic failure, not elsewhere classified	0.716	0.284
H65-H75 Diseases of middle ear and mastoid	0.716	0.284
Q76 Congenital malformations of spine and bony thorax	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
H34 Retinal vascular occlusions	0.714	0.286
H61 Other disorders of external ear	0.714	0.286
K65-K67 Diseases of peritoneum	0.713	0.287
K74.3 Primary biliary cirrhosis	0.713	0.287
K74.0 Hepatic fibrosis	0.713	0.287
S70-S79 Injuries to the hip and thigh	0.713	0.287
K70 Alcoholic liver disease	0.712	0.288
N99-N99 Other disorders of the genitourinary system	0.710	0.289
S00.8 Superficial injury of other parts of head	0.710	0.290
S08 Traumatic amputation of part of head	0.709	0.291
S07 Crushing injury of head	0.709	0.291
S04 Injury of cranial nerves	0.709	0.291
S03 Dislocation, sprain and strain of joints and ligaments of head	0.709	0.291
T46 Poisoning by agents primarily affecting the cardiovascular system	0.708	0.291
S69 Other and unspecified injuries of wrist and hand	0.708	0.292
T86 Failure and rejection of transplanted organs and tissues	0.708	0.292
X20-X29 Contact with venomous animals and plants	0.708	0.292
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.707	0.293
Q35-Q37 Cleft lip and cleft palate	0.707	0.293
Q30-Q34 Congenital malformations of the respiratory system	0.707	0.293
N18.4 Chronic kidney disease, stage 4	0.707	0.293
S09.9 Unspecified injury of head	0.706	0.293
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.706	0.294
H81 Disorders of vestibular function	0.706	0.294
G35-G37 Demyelinating diseases of the central nervous system	0.706	0.294
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.706	0.294
Q21.1 Atrial septal defect	0.705	0.295
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.704	0.296
N15 Other renal tubulo-interstitial diseases	0.704	0.296
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.704	0.296
K36 Other appendicitis	0.703	0.296
Q66 Congenital deformities of feet	0.703	0.297
N13.6 Pyonephrosis	0.703	0.297
I68 Cerebrovascular disorders in diseases classified elsewhere	0.703	0.297
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.703	0.297
I87 Other disorders of veins	0.703	0.297
S05.1 Contusion of eyeball and orbital tissues	0.702	0.298
T80.2 Infections following infusion, transfusion and therapeutic injection	0.702	0.298
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.701	0.299
S00.1 Contusion of eyelid and periocular area	0.699	0.301
H47 Other disorders of optic [2nd] nerve and visual pathways	0.699	0.301
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.698	0.302
K35.0 Acute appendicitis with generalised peritonitis	0.698	0.302
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.698	0.302
J90-J94 Other diseases of pleura	0.698	0.302
I82 Other venous embolism and thrombosis	0.697	0.303
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.697	0.303
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.696	0.304
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.696	0.304
Q83 Congenital malformations of breast	0.693	0.307
E70-E90 Metabolic disorders	0.693	0.307
X10-X19 Contact with heat and hot substances	0.692	0.308
S02.0 Fracture of vault of skull	0.691	0.309
N41 Inflammatory diseases of prostate	0.691	0.309
T15-T19 Effects of foreign body entering through natural orifice	0.691	0.309
W20-W49 Exposure to inanimate mechanical forces	0.690	0.310
I72.4 Aneurysm of artery of lower extremity	0.689	0.311
T90 Sequelae of injuries of head	0.689	0.311
K51.1 Ulcerative (chronic) ileocolitis	0.689	0.311
Q63 Other congenital malformations of kidney	0.689	0.311
S00.7 Multiple superficial injuries of head	0.688	0.312
S00.5 Superficial injury of lip and oral cavity	0.688	0.312
S00.4 Superficial injury of ear	0.688	0.312
S66 Injury of muscle and tendon at wrist and hand level	0.688	0.312
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.688	0.312
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.687	0.313
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.686	0.314
N13.7 Vesicoureteral-reflux-associated uropathy	0.686	0.314
H36 Retinal disorders in diseases classified elsewhere	0.685	0.315
K38 Other diseases of appendix	0.684	0.315
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.683	0.316
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.683	0.316
E20-E35 Disorders of other endocrine glands	0.683	0.317
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.683	0.317
V80-V89 Other land transport accidents	0.682	0.318
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.681	0.319
N28 Other disorders of kidney and ureter, not elsewhere classified	0.681	0.319
X58-X59 Accidental exposure to other and unspecified factors	0.680	0.320
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.680	0.320
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.680	0.320
T41 Poisoning by anaesthetics and therapeutic gases	0.680	0.320
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.680	0.320
S02.20 Fracture of nasal bones (closed)	0.679	0.321
J09-J18 Influenza and pneumonia	0.679	0.321
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.678	0.322
V20-V29 Motorcycle rider injured in transport accident	0.677	0.323
H52.2 Astigmatism	0.676	0.323
K51.4 Pseudopolyposis of colon	0.676	0.324
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.675	0.325
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.674	0.326
N40 Hyperplasia of prostate	0.674	0.326
T93.2 Sequelae of other fractures of lower limb	0.672	0.327
I77.8 Other specified disorders of arteries and arterioles	0.672	0.328
I61 Intracerebral haemorrhage	0.672	0.328
I72.9 Aneurysm of unspecified site	0.671	0.329
Y65 Other misadventures during surgical and medical care	0.671	0.329
Y35-Y36 Legal intervention and operations of war	0.670	0.330
Y10-Y34 Event of undetermined intent	0.670	0.330
Y00-Y09 Assault	0.670	0.330
X85-X99 Assault	0.670	0.330
X30-X39 Exposure to forces of nature	0.670	0.330
X00-X09 Exposure to smoke, fire and flames	0.670	0.330
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.670	0.330
W75-W84 Other accidental threats to breathing	0.670	0.330
W65-W74 Accidental drowning and submersion	0.670	0.330
V98-V99 Other and unspecified transport accidents	0.670	0.330
V95-V97 Air and space transport accidents	0.670	0.330
V90-V94 Water transport accidents	0.670	0.330
V70-V79 Bus occupant injured in transport accident	0.670	0.330
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.670	0.330
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.670	0.330
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.670	0.330
V01-V09 Pedestrian injured in transport accident	0.670	0.330
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.670	0.330
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.670	0.330
G00-G09 Inflammatory diseases of the central nervous system	0.668	0.332
K51.3 Ulcerative (chronic) rectosigmoiditis	0.667	0.333
H31 Other disorders of choroid	0.667	0.333
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.666	0.334
V40-V49 Car occupant injured in transport accident	0.665	0.335
K50.8 Other Crohn's disease	0.665	0.335
N47 Redundant prepuce, phimosis and paraphimosis	0.663	0.337
Q24 Other congenital malformations of heart	0.663	0.337
I72.3 Aneurysm of iliac artery	0.663	0.337
X50-X57 Overexertion, travel and privation	0.662	0.338
S64 Injury of nerves at wrist and hand level	0.661	0.339
I88 Nonspecific lymphadenitis	0.660	0.340
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.660	0.340
N11 Chronic tubulo-interstitial nephritis	0.660	0.340
H51 Other disorders of binocular movement	0.660	0.340
H46 Optic neuritis	0.659	0.341
S92 Fracture of foot, except ankle	0.659	0.341
E40-E46 Malnutrition	0.658	0.342
I27 Other pulmonary heart diseases	0.658	0.342
T45.0 Antiallergic and antiemetic drugs	0.657	0.343
Q38-Q45 Other congenital malformations of the digestive system	0.656	0.344
H44 Disorders of globe	0.656	0.344
N18.2 Chronic kidney disease, stage 2	0.655	0.345
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.655	0.345
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.655	0.345
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.655	0.345
Q79.6 Ehlers-Danlos syndrome	0.654	0.346
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.654	0.346
E67 Other hyperalimentation	0.653	0.346
E68 Sequelae of hyperalimentation	0.653	0.346
H54 Blindness and low vision	0.653	0.347
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.653	0.347
E65 Localised adiposity	0.653	0.347
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.653	0.347
E11.3 With ophthalmic complications	0.652	0.348
K51.5 Mucosal proctocolitis	0.650	0.350
Y60.0 During surgical operation	0.650	0.350
S02.3 Fracture of orbital floor	0.649	0.351
Y95 Nosocomial condition	0.649	0.351
I30-I52 Other forms of heart disease	0.649	0.351
H57.9 Disorder of eye and adnexa, unspecified	0.648	0.352
S02.5 Fracture of tooth	0.648	0.352
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.647	0.353
H61.0 Perichondritis of external ear	0.647	0.353
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.647	0.353
S69.9 Unspecified injury of wrist and hand	0.646	0.354
I72.0 Aneurysm of carotid artery	0.646	0.354
Q05 Spina bifida	0.646	0.354
T98 Sequelae of other and unspecified effects of external causes	0.646	0.354
T95 Sequelae of burns, corrosions and frostbite	0.646	0.354
T94 Sequelae of injuries involving multiple and unspecified body regions	0.646	0.354
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.646	0.354
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.646	0.354
E14 Unspecified diabetes mellitus	0.646	0.354
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.645	0.355
G30-G32 Other degenerative diseases of the nervous system	0.644	0.356
X60-X84 Intentional self-harm	0.643	0.357
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.643	0.357
N13.4 Hydroureter	0.643	0.357
H35.0 Background retinopathy and retinal vascular changes	0.642	0.358
I74.9 Embolism and thrombosis of unspecified artery	0.642	0.358
I67.0 Dissection of cerebral arteries, nonruptured	0.640	0.360
N26 Unspecified contracted kidney	0.640	0.360
H50.1 Divergent concomitant strabismus	0.640	0.360
G70 Myasthenia gravis and other myoneural disorders	0.639	0.361
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.638	0.362
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.637	0.362
E12 Malnutrition-related diabetes mellitus	0.637	0.363
T66-T78 Other and unspecified effects of external causes	0.636	0.363
T83.1 Mechanical complication of other urinary devices and implants	0.637	0.363
S06.0 Concussion	0.636	0.364
Q78 Other osteochondrodysplasias	0.636	0.364
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.636	0.364
Q75 Other congenital malformations of skull and face bones	0.636	0.364
Q74 Other congenital malformations of limb(s)	0.636	0.364
Q73 Reduction defects of unspecified limb	0.636	0.364
Q72 Reduction defects of lower limb	0.636	0.364
Q71 Reduction defects of upper limb	0.636	0.364
Q70 Syndactyly	0.636	0.364
Q69 Polydactyly	0.636	0.364
Q68 Other congenital musculoskeletal deformities	0.636	0.364
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.636	0.364
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.635	0.365
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.634	0.366
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.634	0.366
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.634	0.366
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.634	0.366
I70 Atherosclerosis	0.633	0.366
I98 Other disorders of circulatory system in diseases classified elsewhere	0.633	0.367
H53 Visual disturbances	0.633	0.367
I97.1 Other functional disturbances following cardiac surgery	0.632	0.368
K90-K93 Other diseases of the digestive system	0.632	0.368
T91.3 Sequelae of injury of spinal cord	0.632	0.368
H82 Vertiginous syndromes in diseases classified elsewhere	0.631	0.368
H52.3 Anisometropia and aniseikonia	0.631	0.369
S20-S29 Injuries to the thorax	0.631	0.369
E66.2 Extreme obesity with alveolar hypoventilation	0.631	0.369
E66.1 Drug-induced obesity	0.631	0.369
E66.0 Obesity due to excess calories	0.631	0.369
H52.7 Disorder of refraction, unspecified	0.631	0.369
H52.6 Other disorders of refraction	0.631	0.369
H52.5 Disorders of accommodation	0.631	0.369
H52.4 Presbyopia	0.631	0.369
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.630	0.370
S02.1 Fracture of base of skull	0.629	0.371
S05.8 Other injuries of eye and orbit	0.629	0.371
H74 Other disorders of middle ear and mastoid	0.628	0.372
K50.9 Crohn's disease, unspecified	0.627	0.373
J18 Pneumonia, organism unspecified	0.627	0.373
I86.1 Scrotal varices	0.626	0.373
E10.2 With renal complications	0.625	0.374
G90 Disorders of autonomic nervous system	0.621	0.378
Q65 Congenital deformities of hip	0.621	0.379
N05 Unspecified nephritic syndrome	0.620	0.380
S02.9 Fracture of skull and facial bones, part unspecified	0.620	0.380
S02.7 Multiple fractures involving skull and facial bones	0.620	0.380
E10.3 With ophthalmic complications	0.620	0.380
N48 Other disorders of penis	0.620	0.380
I77.0 Arteriovenous fistula, acquired	0.620	0.380
H32 Chorioretinal disorders in diseases classified elsewhere	0.619	0.381
H30 Chorioretinal inflammation	0.619	0.381
T91.1 Sequelae of fracture of spine	0.619	0.381
H35.7 Separation of retinal layers	0.619	0.381
E10.4 With neurological complications	0.618	0.382
E10.5 With peripheral circulatory complications	0.618	0.382
S09.8 Other specified injuries of head	0.618	0.382
G94 Other disorders of brain in diseases classified elsewhere	0.617	0.382
G98 Other disorders of nervous system, not elsewhere classified	0.617	0.382
G92 Toxic encephalopathy	0.617	0.382
G96.0 Cerebrospinal fluid leak	0.617	0.383
Q27 Other congenital malformations of peripheral vascular system	0.617	0.383
Q82 Other congenital malformations of skin	0.617	0.383
T31 Burns classified according to extent of body surface involved	0.616	0.383
I74.8 Embolism and thrombosis of other arteries	0.616	0.384
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.616	0.384
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.616	0.384
I74.0 Embolism and thrombosis of abdominal aorta	0.616	0.384
G80 Infantile cerebral palsy	0.616	0.384
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.616	0.384
I60.9 Subarachnoid haemorrhage, unspecified	0.615	0.384
Q26 Congenital malformations of great veins	0.615	0.384
Q25 Congenital malformations of great arteries	0.615	0.384
Q22 Congenital malformations of pulmonary and tricuspid valves	0.615	0.384
Q20 Congenital malformations of cardiac chambers and connexions	0.615	0.384
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.615	0.385
I95.2 Hypotension due to drugs	0.615	0.385
J92 Pleural plaque	0.615	0.385
Y84.6 Urinary catheterisation	0.615	0.385
Q54 Hypospadias	0.614	0.386
N28.8 Other specified disorders of kidney and ureter	0.614	0.386
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.613	0.387
N17 Acute renal failure	0.613	0.387
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.612	0.388
N04 Nephrotic syndrome	0.612	0.388
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.612	0.388
S60 Superficial injury of wrist and hand	0.612	0.388
I86.3 Vulval varices	0.611	0.388
I86.2 Pelvic varices	0.611	0.388
I86.0 Sublingual varices	0.611	0.388
I67.2 Cerebral atherosclerosis	0.611	0.389
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.611	0.389
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.610	0.390
T13 Other injuries of lower limb, level unspecified	0.609	0.391
Y48 Anaesthetics and therapeutic gases	0.609	0.391
K65 Peritonitis	0.608	0.392
S91 Open wound of ankle and foot	0.607	0.393
K73.9 Chronic hepatitis, unspecified	0.607	0.393
S51 Open wound of forearm	0.607	0.393
M86-M90 Other osteopathies	0.606	0.394
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.606	0.394
G93 Other disorders of brain	0.606	0.394
S40-S49 Injuries to the shoulder and upper arm	0.606	0.394
H80.8 Other otosclerosis	0.606	0.394
H80.2 Cochlear otosclerosis	0.606	0.394
H80.1 Otosclerosis involving oval window, obliterative	0.606	0.394
H80.0 Otosclerosis involving oval window, nonobliterative	0.606	0.394
I95.8 Other hypotension	0.606	0.394
I95.0 Idiopathic hypotension	0.606	0.394
T91.8 Sequelae of other specified injuries of neck and trunk	0.605	0.395
T91.9 Sequelae of unspecified injury of neck and trunk	0.605	0.395
G82 Paraplegia and tetraplegia	0.605	0.395
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.604	0.395
I81 Portal vein thrombosis	0.604	0.396
J91 Pleural effusion in conditions classified elsewhere	0.604	0.396
T82.1 Mechanical complication of cardiac electronic device	0.603	0.397
I72.6 Aneurysm and dissection of vertebral artery	0.603	0.397
I72.5 Aneurysm and dissection of other precerebral arteries	0.603	0.397
I72.2 Aneurysm of renal artery	0.603	0.397
I72.1 Aneurysm of artery of upper extremity	0.603	0.397
K74.5 Biliary cirrhosis, unspecified	0.603	0.397
K74.4 Secondary biliary cirrhosis	0.603	0.397
K74.2 Hepatic fibrosis with hepatic sclerosis	0.603	0.397
K74.1 Hepatic sclerosis	0.603	0.397
G91.8 Other hydrocephalus	0.602	0.398
G91.3 Posttraumatic hydrocephalus, unspecified	0.602	0.398
G91.2 Normal-pressure hydrocephalus	0.602	0.398
G91.1 Obstructive hydrocephalus	0.602	0.398
G91.0 Communicating hydrocephalus	0.602	0.398
N49.2 Inflammatory disorders of scrotum	0.602	0.398
Q60 Renal agenesis and other reduction defects of kidney	0.601	0.399
I67.7 Cerebral arteritis, not elsewhere classified	0.601	0.399

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations