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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79658056
log Bayes Factor = 13.7273
Chromosome 10   position 74,658,060  (GRCh37) Explore rs79658056 on Ensembl!
Variant rs79658056 is part of Cluster X0264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
D69.6 Thrombocytopenia, unspecified
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
D69 Purpura and other haemorrhagic conditions
0.995 0.005 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
I60-I69 Cerebrovascular diseases
0.990 0.010 0.000
Chapter II Neoplasms
0.989 0.011 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.987 0.013 0.000
Chapter V Mental and behavioural disorders
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
I51 Complications and ill-defined descriptions of heart disease
0.985 0.015 0.000
F30-F39 Mood [affective] disorders
0.981 0.019 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.980 0.020 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.978 0.022 0.000
M06.9 Rheumatoid arthritis, unspecified
0.975 0.025 0.000
I65.2 Occlusion and stenosis of carotid artery
0.975 0.025 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.967 0.033 0.000
Chapter X Diseases of the respiratory system
0.967 0.033 0.000
J90-J94 Other diseases of pleura
0.962 0.038 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.961 0.039 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.960 0.040 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.957 0.043 0.000
J93 Pneumothorax
0.955 0.045 0.000
Chapter XX External causes of morbidity and mortality
0.953 0.047 0.000
D10-D36 Benign neoplasms
0.952 0.048 0.000
C15-C26 Malignant neoplasms of digestive organs
0.949 0.051 0.000
T43.2 Other and unspecified antidepressants
0.949 0.051 0.000
D17 Benign lipomatous neoplasm
0.948 0.052 0.000
F33 Recurrent depressive disorder
0.947 0.053 0.000
I05-I09 Chronic rheumatic heart diseases
0.947 0.053 0.000
I27 Other pulmonary heart diseases
0.946 0.054 0.000
I45 Other conduction disorders
0.945 0.055 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.942 0.058 0.000
O36 Maternal care for other known or suspected foetal problems
0.941 0.059 0.000
J93.9 Pneumothorax, unspecified
0.939 0.061 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.937 0.063 0.000
J60-J70 Lung diseases due to external agents
0.933 0.067 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.930 0.070 0.000
D12.8 Rectum
0.926 0.074 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.921 0.079 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.916 0.084 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.914 0.086 0.000
Chapter VI Diseases of the nervous system
0.908 0.092 0.000
J69 Pneumonitis due to solids and liquids
0.907 0.093 0.000
C44 Other malignant neoplasms of skin
0.905 0.095 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.905 0.095 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.903 0.096 0.000
I51.8 Other ill-defined heart diseases
0.902 0.098 0.000
Q60-Q64 Congenital malformations of the urinary system
0.900 0.100 0.000
F31 Bipolar affective disorder
0.899 0.101 0.000
M60-M63 Disorders of muscles
0.898 0.102 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.897 0.103 0.000
C44.2 Skin of ear and external auricular canal
0.897 0.103 0.000
I27.0 Primary pulmonary hypertension
0.893 0.107 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.891 0.109 0.000
I08 Multiple valve diseases
0.890 0.110 0.000
X60-X84 Intentional self-harm
0.890 0.110 0.000
J69.0 Pneumonitis due to food and vomit
0.888 0.112 0.000
I27.2 Other secondary pulmonary hypertension
0.884 0.116 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.882 0.118 0.000
M10 Gout
0.880 0.120 0.000
M50-M54 Other dorsopathies
0.878 0.122 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.867 0.133 0.000
C20 Malignant neoplasm of rectum
0.867 0.133 0.000
I45.1 Other and unspecified right bundle-branch block
0.866 0.134 0.000
O36.6 Maternal care for excessive foetal growth
0.865 0.135 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.864 0.136 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.861 0.139 0.000
C71 Malignant neoplasm of brain
0.857 0.143 0.000
O47 False labour
0.855 0.145 0.000
C18 Malignant neoplasm of colon
0.853 0.147 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.853 0.147 0.000
F32 Depressive episode
0.852 0.148 0.000
I38 Endocarditis, valve unspecified
0.852 0.148 0.000
I47 Paroxysmal tachycardia
0.851 0.149 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.851 0.149 0.000
I51.7 Cardiomegaly
0.850 0.150 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.850 0.150 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.849 0.151 0.000
Chapter XXI Factors influencing health status and contact with health services
0.847 0.153 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.846 0.154 0.000
I61 Intracerebral haemorrhage
0.844 0.156 0.000
J90 Pleural effusion, not elsewhere classified
0.839 0.161 0.000
T40.2 Other opioids
0.834 0.166 0.000
I51.6 Cardiovascular disease, unspecified
0.833 0.167 0.000
F60-F69 Disorders of adult personality and behaviour
0.833 0.167 0.000
C73 Malignant neoplasm of thyroid gland
0.831 0.169 0.000
C18.7 Sigmoid colon
0.831 0.169 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.830 0.170 0.000
M62 Other disorders of muscle
0.829 0.171 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.828 0.172 0.000
I95 Hypotension
0.828 0.172 0.000
F33.9 Recurrent depressive disorder, unspecified
0.827 0.173 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.826 0.174 0.000
D69.5 Secondary thrombocytopenia
0.825 0.175 0.000
D10 Benign neoplasm of mouth and pharynx
0.824 0.176 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.822 0.178 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.822 0.178 0.000
G20-G26 Extrapyramidal and movement disorders
0.820 0.180 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.816 0.184 0.000
C44.3 Skin of other and unspecified parts of face
0.816 0.184 0.000
W50-W64 Exposure to animate mechanical forces
0.814 0.186 0.000
I46 Cardiac arrest
0.813 0.187 0.000
Q61 Cystic kidney disease
0.813 0.187 0.000
M86-M90 Other osteopathies
0.813 0.187 0.000
S80-S89 Injuries to the knee and lower leg
0.813 0.187 0.000
D11 Benign neoplasm of major salivary glands
0.812 0.188 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.812 0.188 0.000
Z98 Other postsurgical states
0.812 0.188 0.000
J94 Other pleural conditions
0.810 0.190 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.809 0.191 0.000
J93.1 Other spontaneous pneumothorax
0.809 0.191 0.000
G90-G99 Other disorders of the nervous system
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.192 0.000
M10.9 Gout, unspecified
0.805 0.195 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.804 0.196 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.803 0.197 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.802 0.198 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.801 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.801 0.199 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.800 0.200 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.800 0.200 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.800 0.200 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.799 0.201 0.000
S90-S99 Injuries to the ankle and foot
0.798 0.202 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.798 0.202 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.797 0.203 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.797 0.203 0.000
Q00-Q07 Congenital malformations of the nervous system
0.797 0.203 0.000
I45.2 Bifascicular block
0.796 0.204 0.000
I51.9 Heart disease, unspecified
0.796 0.204 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.793 0.207 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.790 0.210 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.790 0.210 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.789 0.211 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.788 0.211 0.000
Z97 Presence of other devices
0.786 0.214 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.786 0.214 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.786 0.214 0.000
O43 Placental disorders
0.786 0.214 0.000
M54 Dorsalgia
0.783 0.217 0.000
I33 Acute and subacute endocarditis
0.782 0.218 0.000
M62.8 Other specified disorders of muscle
0.780 0.220 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.780 0.220 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.778 0.222 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.778 0.222 0.000
Z95.4 Presence of other heart-valve replacement
0.777 0.223 0.000
M20-M25 Other joint disorders
0.776 0.224 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.776 0.224 0.000
J93.8 Other pneumothorax
0.775 0.225 0.000
Z95.2 Presence of prosthetic heart valve
0.774 0.226 0.000
I51.4 Myocarditis, unspecified
0.773 0.227 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.772 0.228 0.000
Chapter I Certain infectious and parasitic diseases
0.772 0.228 0.000
O36.8 Maternal care for other specified foetal problems
0.769 0.231 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.767 0.232 0.000
M51 Other intervertebral disk disorders
0.767 0.233 0.000
Q80-Q89 Other congenital malformations
0.767 0.233 0.000
D69.9 Haemorrhagic condition, unspecified
0.766 0.234 0.000
D12.3 Transverse colon
0.765 0.235 0.000
T42.4 Benzodiazepines
0.765 0.235 0.000
S00-S09 Injuries to the head
0.764 0.236 0.000
Z98.8 Other specified postsurgical states
0.764 0.236 0.000
M06.0 Seronegative rheumatoid arthritis
0.763 0.237 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.763 0.237 0.000
Z93 Artificial opening status
0.762 0.238 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.762 0.238 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.761 0.239 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.759 0.240 0.000
I47.2 Ventricular tachycardia
0.758 0.242 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.757 0.243 0.000
C71.9 Brain, unspecified
0.757 0.243 0.000
M10.99 Gout, unspecified (Site unspecified)
0.756 0.244 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.755 0.245 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.754 0.245 0.000
C18.9 Colon, unspecified
0.753 0.247 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.752 0.248 0.000
O23 Infections of genito-urinary tract in pregnancy
0.752 0.248 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.751 0.249 0.000
D34 Benign neoplasm of thyroid gland
0.751 0.249 0.000
Z89 Acquired absence of limb
0.751 0.249 0.000
I99 Other and unspecified disorders of circulatory system
0.750 0.250 0.000
M31 Other necrotising vasculopathies
0.749 0.251 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.749 0.251 0.000
I61.8 Other intracerebral haemorrhage
0.749 0.251 0.000
T51 Toxic effect of alcohol
0.748 0.252 0.000
I07 Rheumatic tricuspid valve diseases
0.747 0.253 0.000
I69 Sequelae of cerebrovascular disease
0.746 0.253 0.000
V10-V19 Pedal cyclist injured in transport accident
0.745 0.254 0.000
F31.9 Bipolar affective disorder, unspecified
0.745 0.255 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.745 0.255 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
D70 Agranulocytosis
0.745 0.255 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.744 0.256 0.000
Z98.0 Intestinal bypass and anastomosis status
0.744 0.256 0.000
D68 Other coagulation defects
0.743 0.257 0.000
Z91.5 Personal history of self-harm
0.741 0.259 0.000
I30 Acute pericarditis
0.739 0.261 0.000
Z76 Persons encountering health services in other circumstances
0.739 0.261 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.736 0.264 0.000
T00-T07 Injuries involving multiple body regions
0.735 0.265 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.733 0.266 0.000
I45.4 Nonspecific intraventricular block
0.733 0.267 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.733 0.267 0.000
G20 Parkinson's disease
0.732 0.268 0.000
I35 Nonrheumatic aortic valve disorders
0.731 0.269 0.000
X62.9 Unspecified place
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.731 0.269 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.730 0.270 0.000
I42 Cardiomyopathy
0.730 0.270 0.000
I95.9 Hypotension, unspecified
0.729 0.271 0.000
I08.0 Disorders of both mitral and aortic valves
0.728 0.272 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.728 0.272 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.727 0.273 0.000
Z74 Problems related to care-provider dependency
0.727 0.273 0.000
I46.9 Cardiac arrest, unspecified
0.727 0.273 0.000
I63 Cerebral infarction
0.727 0.273 0.000
F80-F89 Disorders of psychological development
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.726 0.274 0.000
T91 Sequelae of injuries of neck and trunk
0.726 0.274 0.000
M54.2 Cervicalgia
0.726 0.274 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.725 0.274 0.000
I27.8 Other specified pulmonary heart diseases
0.725 0.275 0.000
X10-X19 Contact with heat and hot substances
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.276 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.724 0.276 0.000
D66 Hereditary factor VIII deficiency
0.723 0.277 0.000
M31.6 Other giant cell arteritis
0.722 0.278 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.722 0.278 0.000
S80 Superficial injury of lower leg
0.722 0.278 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
M54.1 Radiculopathy
0.719 0.281 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.719 0.281 0.000
I45.6 Preexcitation syndrome
0.719 0.281 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
O36.9 Maternal care for foetal problem, unspecified
0.718 0.282 0.000
D31 Benign neoplasm of eye and adnexa
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
O41 Other disorders of amniotic fluid and membranes
0.716 0.284 0.000
F30 Manic episode
0.716 0.284 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.716 0.284 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.716 0.284 0.000
T43.9 Psychotropic drug, unspecified
0.716 0.284 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.716 0.284 0.000
T43.6 Psychostimulants with abuse potential
0.716 0.284 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
J09-J18 Influenza and pneumonia
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.714 0.286 0.000
D69.8 Other specified haemorrhagic conditions
0.714 0.286 0.000
D69.4 Other primary thrombocytopenia
0.714 0.286 0.000
D69.2 Other nonthrombocytopenic purpura
0.714 0.286 0.000
D69.1 Qualitative platelet defects
0.714 0.286 0.000
D69.0 Allergic purpura
0.714 0.286 0.000
D67 Hereditary factor IX deficiency
0.714 0.286 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.714 0.286 0.000
T42.1 Iminostilbenes
0.714 0.286 0.000
D11.0 Parotid gland
0.712 0.288 0.000
O47.0 False labour before 37 completed weeks of gestation
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.711 0.289 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.710 0.290 0.000
O44 Placenta praevia
0.710 0.290 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.710 0.290 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.710 0.290 0.000
O21 Excessive vomiting in pregnancy
0.709 0.291 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
C25 Malignant neoplasm of pancreas
0.709 0.291 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.709 0.291 0.000
T39.0 Salicylates
0.709 0.291 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.708 0.292 0.000
J86 Pyothorax
0.708 0.292 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.708 0.292 0.000
F70-F79 Mental retardation
0.708 0.292 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.708 0.292 0.000
F17.1 Harmful use
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I51.5 Myocardial degeneration
0.706 0.294 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.706 0.294 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.706 0.294 0.000
I51.0 Cardiac septal defect, acquired
0.706 0.294 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.294 0.000
M12 Other specific arthropathies
0.706 0.294 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.294 0.000
M08 Juvenile arthritis
0.706 0.294 0.000
D16 Benign neoplasm of bone and articular cartilage
0.705 0.295 0.000
I62 Other nontraumatic intracranial haemorrhage
0.705 0.295 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.704 0.296 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
I05 Rheumatic mitral valve diseases
0.704 0.296 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.703 0.297 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.703 0.297 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.703 0.297 0.000
I65.1 Occlusion and stenosis of basilar artery
0.703 0.297 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.703 0.297 0.000
D27 Benign neoplasm of ovary
0.703 0.297 0.000
Q63 Other congenital malformations of kidney
0.703 0.297 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.297 0.000
M06.4 Inflammatory polyarthropathy
0.702 0.297 0.000
M06.2 Rheumatoid bursitis
0.702 0.297 0.000
M06.1 Adult-onset Still's disease
0.702 0.297 0.000
C43 Malignant melanoma of skin
0.702 0.298 0.000
M05 Seropositive rheumatoid arthritis
0.702 0.298 0.000
O45 Premature separation of placenta [abruptio placentae]
0.701 0.299 0.000
O33 Maternal care for known or suspected disproportion
0.701 0.299 0.000
O31 Complications specific to multiple gestation
0.701 0.299 0.000
A30-A49 Other bacterial diseases
0.701 0.299 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.699 0.301 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
I50 Heart failure
0.698 0.302 0.000
F60 Specific personality disorders
0.698 0.302 0.000
D10.1 Tongue
0.698 0.302 0.000
M06.3 Rheumatoid nodule
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.304 0.000
T51.0 Ethanol
0.695 0.305 0.000
I95.1 Orthostatic hypotension
0.695 0.305 0.000
C24.0 Extrahepatic bile duct
0.695 0.305 0.000
M65 Synovitis and tenosynovitis
0.695 0.305 0.000
C71.2 Temporal lobe
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
M89 Other disorders of bone
0.693 0.307 0.000
C23 Malignant neoplasm of gallbladder
0.693 0.307 0.000
J94.8 Other specified pleural conditions
0.692 0.308 0.000
Y45.2 Propionic acid derivatives
0.691 0.309 0.000
O30 Multiple gestation
0.690 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.310 0.000
I28 Other diseases of pulmonary vessels
0.689 0.311 0.000
D12.0 Caecum
0.689 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.688 0.312 0.000
I45.9 Conduction disorder, unspecified
0.688 0.312 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.688 0.312 0.000
O40 Polyhydramnios
0.687 0.312 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.687 0.313 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.687 0.313 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.687 0.313 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.687 0.313 0.000
C45 Mesothelioma
0.687 0.313 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.686 0.314 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.686 0.314 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.685 0.314 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
J93.0 Spontaneous tension pneumothorax
0.684 0.315 0.000
S10-S19 Injuries to the neck
0.684 0.316 0.000
C71.0 Cerebrum, except lobes and ventricles
0.684 0.316 0.000
G93 Other disorders of brain
0.684 0.316 0.000
G35 Multiple sclerosis
0.683 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
Y00-Y09 Assault
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
D29 Benign neoplasm of male genital organs
0.682 0.318 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.682 0.318 0.000
D19 Benign neoplasm of mesothelial tissue
0.682 0.318 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.682 0.318 0.000
M80-M85 Disorders of bone density and structure
0.682 0.318 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.681 0.319 0.000
C17 Malignant neoplasm of small intestine
0.681 0.319 0.000
T16 Foreign body in ear
0.680 0.320 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.680 0.320 0.000
M51.2 Other specified intervertebral disk displacement
0.679 0.321 0.000
F33.8 Other recurrent depressive disorders
0.679 0.321 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.679 0.321 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.679 0.321 0.000
I09 Other rheumatic heart diseases
0.679 0.321 0.000
I06 Rheumatic aortic valve diseases
0.679 0.321 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.679 0.321 0.000
I27.1 Kyphoscoliotic heart disease
0.678 0.322 0.000
T90 Sequelae of injuries of head
0.678 0.322 0.000
I45.8 Other specified conduction disorders
0.678 0.322 0.000
I45.3 Trifascicular block
0.678 0.322 0.000
I45.0 Right fascicular block
0.678 0.322 0.000
T46.1 Calcium-channel blockers
0.677 0.322 0.000
M54.22 Cervicalgia (Cervical region)
0.677 0.323 0.000
Q61.3 Polycystic kidney, unspecified
0.677 0.323 0.000
Z97.8 Presence of other specified devices
0.677 0.323 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.677 0.323 0.000
T39.1 4-Aminophenol derivatives
0.676 0.324 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.675 0.325 0.000
D12.4 Descending colon
0.675 0.325 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.675 0.325 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.675 0.325 0.000
O36.4 Maternal care for intra-uterine death
0.675 0.325 0.000
O36.2 Maternal care for hydrops foetalis
0.675 0.325 0.000
O36.1 Maternal care for other isoimmunisation
0.675 0.325 0.000
Q05 Spina bifida
0.674 0.326 0.000
M21 Other acquired deformities of limbs
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.673 0.327 0.000
S50-S59 Injuries to the elbow and forearm
0.672 0.327 0.000
E10-E14 Diabetes mellitus
0.670 0.330 0.000
Q61.2 Polycystic kidney, adult type
0.670 0.330 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.669 0.330 0.000
C69 Malignant neoplasm of eye and adnexa
0.669 0.331 0.000
I08.8 Other multiple valve diseases
0.669 0.331 0.000
J70 Respiratory conditions due to other external agents
0.669 0.331 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.669 0.331 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.669 0.331 0.000
J66 Airway disease due to specific organic dust
0.669 0.331 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.669 0.331 0.000
J62 Pneumoconiosis due to dust containing silica
0.669 0.331 0.000
J65 Pneumoconiosis associated with tuberculosis
0.669 0.331 0.000
J64 Unspecified pneumoconiosis
0.669 0.331 0.000
J60 Coalworker's pneumoconiosis
0.669 0.331 0.000
D30 Benign neoplasm of urinary organs
0.669 0.331 0.000
Z82.3 Family history of stroke
0.669 0.331 0.000
M62.88 Other specified disorders of muscle (Other)
0.668 0.332 0.000
M91-M94 Chondropathies
0.667 0.333 0.000
D12.9 Anus and anal canal
0.667 0.333 0.000
D12.1 Appendix
0.667 0.333 0.000
E20-E35 Disorders of other endocrine glands
0.667 0.333 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.666 0.334 0.000
Z97.0 Presence of artificial eye
0.666 0.334 0.000
O43.1 Malformation of placenta
0.665 0.335 0.000
O20 Haemorrhage in early pregnancy
0.662 0.337 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.662 0.338 0.000
C15 Malignant neoplasm of oesophagus
0.661 0.339 0.000
C51-C58 Malignant neoplasms of female genital organs
0.661 0.339 0.000
Y40 Systemic antibiotics
0.661 0.339 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.660 0.339 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.660 0.339 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.660 0.339 0.000
T42.3 Barbiturates
0.660 0.339 0.000
T42.2 Succinimides and oxazolidinediones
0.660 0.339 0.000
T42.0 Hydantoin derivatives
0.660 0.339 0.000
O48 Prolonged pregnancy
0.660 0.340 0.000
E11 Non-insulin-dependent diabetes mellitus
0.660 0.340 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.660 0.340 0.000
X78 Intentional self-harm by sharp object
0.659 0.341 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.659 0.341 0.000
X63.0 Home
0.658 0.342 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
G40-G47 Episodic and paroxysmal disorders
0.656 0.344 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.655 0.345 0.000
C70 Malignant neoplasm of meninges
0.655 0.345 0.000
I27.9 Pulmonary heart disease, unspecified
0.655 0.345 0.000
D10.3 Other and unspecified parts of mouth
0.654 0.346 0.000
D12.5 Sigmoid colon
0.654 0.346 0.000
G25 Other extrapyramidal and movement disorders
0.654 0.346 0.000
T45.5 Anticoagulants
0.652 0.348 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.651 0.349 0.000
C71.1 Frontal lobe
0.650 0.350 0.000
J69.8 Pneumonitis due to other solids and liquids
0.650 0.350 0.000
J69.1 Pneumonitis due to oils and essences
0.650 0.350 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.649 0.351 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.649 0.351 0.000
C44.8 Overlapping lesion of skin
0.649 0.351 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.649 0.351 0.000
T39.4 Antirheumatics, not elsewhere classified
0.649 0.351 0.000
T39.2 Pyrazolone derivatives
0.649 0.351 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.649 0.351 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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