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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79722283
log Bayes Factor = 12.398
Chromosome 2   position 56,869,337  (GRCh37) Explore rs79722283 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.997 0.003 0.000
D70 Agranulocytosis
0.996 0.004 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.994 0.006 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
A30-A49 Other bacterial diseases
0.982 0.018 0.000
Y43 Primarily systemic agents
0.982 0.018 0.000
M13 Other arthritis
0.981 0.019 0.000
M70-M79 Other soft tissue disorders
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
A41 Other septicaemia
0.975 0.025 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.973 0.027 0.000
S00-S09 Injuries to the head
0.970 0.030 0.000
Y43.3 Other antineoplastic drugs
0.968 0.032 0.000
M13.9 Arthritis, unspecified
0.968 0.032 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.967 0.033 0.000
M06.9 Rheumatoid arthritis, unspecified
0.965 0.035 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.963 0.037 0.000
E00-E07 Disorders of thyroid gland
0.961 0.039 0.000
L20-L30 Dermatitis and eczema
0.953 0.047 0.000
A41.9 Septicaemia, unspecified
0.953 0.047 0.000
Chapter II Neoplasms
0.951 0.049 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.951 0.049 0.000
B35-B49 Mycoses
0.950 0.050 0.000
E70-E90 Metabolic disorders
0.950 0.050 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.946 0.054 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.945 0.055 0.000
M45-M49 Spondylopathies
0.938 0.062 0.000
Y84.0 Cardiac catheterisation
0.937 0.063 0.000
E04 Other non-toxic goitre
0.936 0.064 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.934 0.066 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.925 0.075 0.000
E14 Unspecified diabetes mellitus
0.917 0.083 0.000
M65-M68 Disorders of synovium and tendon
0.912 0.088 0.000
E04.2 Non-toxic multinodular goitre
0.909 0.091 0.000
E11 Non-insulin-dependent diabetes mellitus
0.906 0.094 0.000
B37 Candidiasis
0.904 0.096 0.000
L27 Dermatitis due to substances taken internally
0.895 0.105 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.895 0.105 0.000
L30 Other dermatitis
0.894 0.106 0.000
E16 Other disorders of pancreatic internal secretion
0.887 0.113 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.882 0.118 0.000
M47 Spondylosis
0.878 0.122 0.000
S80-S89 Injuries to the knee and lower leg
0.876 0.124 0.000
M79.0 Rheumatism, unspecified
0.876 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.873 0.127 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.872 0.128 0.000
T93 Sequelae of injuries of lower limb
0.871 0.129 0.000
E87.7 Fluid overload
0.871 0.129 0.000
M80-M85 Disorders of bone density and structure
0.868 0.132 0.000
M10 Gout
0.865 0.135 0.000
M13.98 Arthritis, unspecified (Other)
0.863 0.137 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.863 0.137 0.000
Y84.6 Urinary catheterisation
0.863 0.137 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.862 0.138 0.000
S02 Fracture of skull and facial bones
0.861 0.139 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.861 0.139 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.854 0.145 0.000
E16.2 Hypoglycaemia, unspecified
0.854 0.146 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.851 0.149 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.850 0.150 0.000
V20-V29 Motorcycle rider injured in transport accident
0.848 0.152 0.000
B37.8 Candidiasis of other sites
0.848 0.152 0.000
S00 Superficial injury of head
0.846 0.154 0.000
E14.3 With ophthalmic complications
0.846 0.154 0.000
C50-C50 Malignant neoplasm of breast
0.841 0.159 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.841 0.159 0.000
H60-H62 Diseases of external ear
0.840 0.160 0.000
C92 Myeloid leukaemia
0.840 0.160 0.000
M47.9 Spondylosis, unspecified
0.838 0.162 0.000
D10-D36 Benign neoplasms
0.833 0.167 0.000
L30.9 Dermatitis, unspecified
0.833 0.167 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.832 0.168 0.000
M06.0 Seronegative rheumatoid arthritis
0.832 0.168 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.832 0.168 0.000
E11.3 With ophthalmic complications
0.830 0.170 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.830 0.170 0.000
Y84.8 Other medical procedures
0.829 0.171 0.000
T66-T78 Other and unspecified effects of external causes
0.829 0.171 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.828 0.172 0.000
Y85 Sequelae of transport accidents
0.827 0.173 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.824 0.176 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.824 0.176 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.824 0.176 0.000
S40-S49 Injuries to the shoulder and upper arm
0.823 0.177 0.000
M06.3 Rheumatoid nodule
0.822 0.178 0.000
C81 Hodgkin's disease
0.822 0.178 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.822 0.178 0.000
B65-B83 Helminthiases
0.821 0.178 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.819 0.181 0.000
D22 Melanocytic naevi
0.814 0.186 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.813 0.187 0.000
M75 Shoulder lesions
0.811 0.189 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.810 0.190 0.000
M65 Synovitis and tenosynovitis
0.810 0.190 0.000
S06 Intracranial injury
0.807 0.193 0.000
D60-D64 Aplastic and other anaemias
0.807 0.193 0.000
Y52 Agents primarily affecting the cardiovascular system
0.806 0.194 0.000
S01 Open wound of head
0.805 0.195 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.804 0.196 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.804 0.196 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.803 0.197 0.000
E04.9 Non-toxic goitre, unspecified
0.803 0.197 0.000
H61 Other disorders of external ear
0.802 0.198 0.000
M79.8 Other specified soft tissue disorders
0.802 0.198 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.801 0.198 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.801 0.199 0.000
E87.2 Acidosis
0.801 0.199 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.799 0.201 0.000
C91 Lymphoid leukaemia
0.798 0.202 0.000
Chapter V Mental and behavioural disorders
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
D75 Other diseases of blood and blood-forming organs
0.795 0.205 0.000
Y84.1 Kidney dialysis
0.795 0.205 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
B44 Aspergillosis
0.794 0.206 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.793 0.207 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.789 0.211 0.000
M06.4 Inflammatory polyarthropathy
0.788 0.212 0.000
T92 Sequelae of injuries of upper limb
0.788 0.212 0.000
M07 Psoriatic and enteropathic arthropathies
0.788 0.212 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.787 0.213 0.000
Y43.1 Antineoplastic antimetabolites
0.785 0.215 0.000
C83.3 Large cell (diffuse)
0.783 0.217 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.783 0.217 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.783 0.217 0.000
S70-S79 Injuries to the hip and thigh
0.781 0.219 0.000
A41.8 Other specified septicaemia
0.779 0.221 0.000
Y85.0 Sequelae of motor-vehicle accident
0.779 0.221 0.000
Y40 Systemic antibiotics
0.777 0.223 0.000
M76 Enthesopathies of lower limb, excluding foot
0.775 0.224 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.775 0.225 0.000
B37.9 Candidiasis, unspecified
0.774 0.226 0.000
M84 Disorders of continuity of bone
0.773 0.227 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.773 0.227 0.000
M86-M90 Other osteopathies
0.770 0.230 0.000
M10.9 Gout, unspecified
0.768 0.232 0.000
S02.5 Fracture of tooth
0.767 0.233 0.000
C50 Malignant neoplasm of breast
0.763 0.237 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.761 0.239 0.000
E83 Disorders of mineral metabolism
0.761 0.239 0.000
D24 Benign neoplasm of breast
0.759 0.241 0.000
E10 Insulin-dependent diabetes mellitus
0.759 0.241 0.000
E14.9 Without complications
0.759 0.241 0.000
M45 Ankylosing spondylitis
0.756 0.244 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.755 0.245 0.000
T86 Failure and rejection of transplanted organs and tissues
0.755 0.245 0.000
T91 Sequelae of injuries of neck and trunk
0.754 0.246 0.000
M67 Other disorders of synovium and tendon
0.753 0.247 0.000
S02.1 Fracture of base of skull
0.749 0.251 0.000
S20-S29 Injuries to the thorax
0.749 0.251 0.000
L50-L54 Urticaria and erythema
0.747 0.253 0.000
X20-X29 Contact with venomous animals and plants
0.747 0.253 0.000
H61.0 Perichondritis of external ear
0.747 0.253 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.746 0.254 0.000
V10-V19 Pedal cyclist injured in transport accident
0.745 0.255 0.000
M13.94 Arthritis, unspecified (Hand)
0.745 0.255 0.000
X50-X57 Overexertion, travel and privation
0.745 0.255 0.000
L21 Seborrhoeic dermatitis
0.745 0.255 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
E11.5 With peripheral circulatory complications
0.744 0.256 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.743 0.257 0.000
E40-E46 Malnutrition
0.742 0.258 0.000
A49 Bacterial infection of unspecified site
0.742 0.258 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.742 0.258 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.741 0.259 0.000
E87.0 Hyperosmolality and hypernatraemia
0.741 0.259 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.739 0.261 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.739 0.261 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.739 0.261 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.737 0.263 0.000
S01.2 Open wound of nose
0.736 0.264 0.000
Y43.4 Immunosuppressive agents
0.735 0.265 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.733 0.267 0.000
T63 Toxic effect of contact with venomous animals
0.733 0.267 0.000
C51-C58 Malignant neoplasms of female genital organs
0.733 0.267 0.000
C92.0 Acute myeloid leukaemia
0.733 0.267 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.732 0.268 0.000
M60-M63 Disorders of muscles
0.732 0.268 0.000
S05 Injury of eye and orbit
0.732 0.268 0.000
E88 Other metabolic disorders
0.730 0.269 0.000
E11.9 Without complications
0.729 0.271 0.000
M13.93 Arthritis, unspecified (Forearm)
0.729 0.271 0.000
M85 Other disorders of bone density and structure
0.728 0.272 0.000
L28 Lichen simplex chronicus and prurigo
0.726 0.274 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.726 0.274 0.000
A40 Streptococcal septicaemia
0.725 0.274 0.000
S00.8 Superficial injury of other parts of head
0.725 0.275 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.725 0.275 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.725 0.275 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.277 0.000
S86 Injury of muscle and tendon at lower leg level
0.722 0.278 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
C85.1 B-cell lymphoma, unspecified
0.722 0.278 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.721 0.279 0.000
S50-S59 Injuries to the elbow and forearm
0.721 0.279 0.000
L30.8 Other specified dermatitis
0.721 0.279 0.000
M75.0 Adhesive capsulitis of shoulder
0.721 0.279 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.720 0.280 0.000
A46 Erysipelas
0.719 0.281 0.000
E89.0 Postprocedural hypothyroidism
0.719 0.281 0.000
C50.4 Upper-outer quadrant of breast
0.718 0.282 0.000
M13.0 Polyarthritis, unspecified
0.717 0.282 0.000
D80-D89 Certain disorders involving the immune mechanism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
M77 Other enthesopathies
0.716 0.284 0.000
M79.1 Myalgia
0.715 0.285 0.000
T59 Toxic effect of other gases, fumes and vapours
0.715 0.285 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.715 0.285 0.000
D74 Methaemoglobinaemia
0.715 0.285 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.715 0.285 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.715 0.285 0.000
Y57 Other and unspecified drugs and medicaments
0.713 0.286 0.000
B37.1 Pulmonary candidiasis
0.713 0.287 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.712 0.287 0.000
Y59 Other and unspecified vaccines and biological substances
0.712 0.288 0.000
Y58 Bacterial vaccines
0.712 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.712 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.712 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.712 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.712 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.712 0.288 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
M06.8 Other specified rheumatoid arthritis
0.710 0.290 0.000
M06.2 Rheumatoid bursitis
0.710 0.290 0.000
M06.1 Adult-onset Still's disease
0.710 0.290 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
D63.0 Anaemia in neoplastic disease
0.709 0.291 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.708 0.292 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.708 0.292 0.000
C81.9 Hodgkin's disease, unspecified
0.708 0.292 0.000
E04.0 Non-toxic diffuse goitre
0.707 0.293 0.000
L29 Pruritus
0.706 0.294 0.000
F30-F39 Mood [affective] disorders
0.706 0.294 0.000
M79.7 Fibromyalgia
0.705 0.295 0.000
A48 Other bacterial diseases, not elsewhere classified
0.704 0.296 0.000
A44 Bartonellosis
0.704 0.296 0.000
A43 Nocardiosis
0.704 0.296 0.000
A42 Actinomycosis
0.704 0.296 0.000
A39 Meningococcal infection
0.704 0.296 0.000
A37 Whooping cough
0.704 0.296 0.000
A36 Diphtheria
0.704 0.296 0.000
A32 Listeriosis
0.704 0.296 0.000
A31 Infection due to other mycobacteria
0.704 0.296 0.000
A30 Leprosy [Hansen's disease]
0.704 0.296 0.000
A38 Scarlet fever
0.704 0.296 0.000
A35 Other tetanus
0.704 0.296 0.000
A34 Obstetrical tetanus
0.704 0.296 0.000
A33 Tetanus neonatorum
0.704 0.296 0.000
Y43.9 Primarily systemic agent, unspecified
0.704 0.296 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.704 0.296 0.000
Y43.6 Enzymes, not elsewhere classified
0.704 0.296 0.000
Y43.5 Acidifying and alkalising agents
0.704 0.296 0.000
Y43.2 Antineoplastic natural products
0.704 0.296 0.000
Y43.0 Antiallergic and antiemetic drugs
0.704 0.296 0.000
M79.5 Residual foreign body in soft tissue
0.704 0.296 0.000
M13.8 Other specified arthritis
0.704 0.296 0.000
M13.1 Monoarthritis, not elsewhere classified
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.702 0.298 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
E05.9 Thyrotoxicosis, unspecified
0.702 0.298 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.701 0.299 0.000
B49 Unspecified mycosis
0.701 0.299 0.000
B80 Enterobiasis
0.701 0.299 0.000
D75.1 Secondary polycythaemia
0.701 0.299 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.700 0.300 0.000
S02.50 Fracture of tooth (closed)
0.700 0.300 0.000
A41.4 Septicaemia due to anaerobes
0.699 0.301 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.699 0.301 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.699 0.301 0.000
M46 Other inflammatory spondylopathies
0.698 0.302 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
S08 Traumatic amputation of part of head
0.696 0.304 0.000
S07 Crushing injury of head
0.696 0.304 0.000
S04 Injury of cranial nerves
0.696 0.304 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.696 0.304 0.000
H60 Otitis externa
0.695 0.305 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.695 0.305 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.694 0.306 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.694 0.306 0.000
M11 Other crystal arthropathies
0.694 0.306 0.000
Y84.9 Medical procedure, unspecified
0.693 0.306 0.000
Y84.7 Blood-sampling
0.693 0.306 0.000
Y84.5 Insertion of gastric or duodenal sound
0.693 0.306 0.000
Y84.4 Aspiration of fluid
0.693 0.306 0.000
Y84.3 Shock therapy
0.693 0.306 0.000
D32 Benign neoplasm of meninges
0.692 0.308 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.692 0.308 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.692 0.308 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.692 0.308 0.000
L10-L14 Bullous disorders
0.690 0.309 0.000
E11.8 With unspecified complications
0.690 0.310 0.000
Y60.0 During surgical operation
0.689 0.311 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.689 0.311 0.000
E00 Congenital iodine-deficiency syndrome
0.689 0.311 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.689 0.311 0.000
S81 Open wound of lower leg
0.689 0.311 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.311 0.000
M91-M94 Chondropathies
0.688 0.312 0.000
E65-E68 Obesity and other hyperalimentation
0.688 0.312 0.000
T92.1 Sequelae of fracture of arm
0.687 0.313 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.685 0.315 0.000
M47.1 Other spondylosis with myelopathy
0.685 0.315 0.000
L25 Unspecified contact dermatitis
0.683 0.317 0.000
L24 Irritant contact dermatitis
0.683 0.317 0.000
L23 Allergic contact dermatitis
0.683 0.317 0.000
L20 Atopic dermatitis
0.683 0.317 0.000
L26 Exfoliative dermatitis
0.683 0.317 0.000
L22 Diaper [napkin] dermatitis
0.683 0.317 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.683 0.317 0.000
S42 Fracture of shoulder and upper arm
0.683 0.317 0.000
M79.2 Neuralgia and neuritis, unspecified
0.683 0.317 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.682 0.318 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.682 0.318 0.000
T95 Sequelae of burns, corrosions and frostbite
0.682 0.318 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.682 0.318 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.682 0.318 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.682 0.318 0.000
B48 Other mycoses, not elsewhere classified
0.681 0.318 0.000
B47 Mycetoma
0.681 0.318 0.000
B46 Zygomycosis
0.681 0.318 0.000
B45 Cryptococcosis
0.681 0.318 0.000
B43 Chromomycosis and phaeomycotic abscess
0.681 0.318 0.000
B42 Sporotrichosis
0.681 0.318 0.000
B41 Paracoccidioidomycosis
0.681 0.318 0.000
B40 Blastomycosis
0.681 0.318 0.000
B39 Histoplasmosis
0.681 0.318 0.000
B38 Coccidioidomycosis
0.681 0.318 0.000
B36 Other superficial mycoses
0.681 0.318 0.000
E85 Amyloidosis
0.681 0.319 0.000
E84 Cystic fibrosis
0.681 0.319 0.000
E79 Disorders of purine and pyrimidine metabolism
0.681 0.319 0.000
E77 Disorders of glycoprotein metabolism
0.681 0.319 0.000
E76 Disorders of glycosaminoglycan metabolism
0.681 0.319 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.681 0.319 0.000
E74 Other disorders of carbohydrate metabolism
0.681 0.319 0.000
E73 Lactose intolerance
0.681 0.319 0.000
E72 Other disorders of amino-acid metabolism
0.681 0.319 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.681 0.319 0.000
E70 Disorders of aromatic amino-acid metabolism
0.681 0.319 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.681 0.319 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.681 0.319 0.000
E83.1 Disorders of iron metabolism
0.680 0.320 0.000
Y86 Sequelae of other accidents
0.680 0.320 0.000
Y44 Agents primarily affecting blood constituents
0.680 0.320 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.679 0.321 0.000
T98 Sequelae of other and unspecified effects of external causes
0.679 0.321 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.679 0.321 0.000
C95 Leukaemia of unspecified cell type
0.679 0.321 0.000
C94 Other leukaemias of specified cell type
0.679 0.321 0.000
C93 Monocytic leukaemia
0.679 0.321 0.000
C88 Malignant immunoproliferative diseases
0.679 0.321 0.000
C86 Other specified types of T/NK-cell lymphoma
0.679 0.321 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.679 0.321 0.000
D72 Other disorders of white blood cells
0.678 0.321 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.678 0.322 0.000
M79.9 Soft tissue disorder, unspecified
0.677 0.323 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.677 0.323 0.000
M79.3 Panniculitis, unspecified
0.677 0.323 0.000
T78 Adverse effects, not elsewhere classified
0.676 0.324 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.676 0.324 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.676 0.324 0.000
C91.1 Chronic lymphocytic leukaemia
0.675 0.324 0.000
M79.6 Pain in limb
0.675 0.325 0.000
T86.0 Bone-marrow transplant rejection
0.675 0.325 0.000
E11.6 With other specified complications
0.674 0.325 0.000
B15-B19 Viral hepatitis
0.674 0.326 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.673 0.327 0.000
T51 Toxic effect of alcohol
0.673 0.327 0.000
M49 Spondylopathies in diseases classified elsewhere
0.673 0.327 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.672 0.328 0.000
C50.2 Upper-inner quadrant of breast
0.672 0.328 0.000
E04.8 Other specified non-toxic goitre
0.671 0.328 0.000
C92.1 Chronic myeloid leukaemia
0.671 0.329 0.000
T93.0 Sequelae of open wound of lower limb
0.671 0.329 0.000
M70.4 Prepatellar bursitis
0.670 0.330 0.000
E15 Nondiabetic hypoglycaemic coma
0.670 0.330 0.000
W00-W19 Falls
0.670 0.330 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.670 0.330 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.669 0.331 0.000
S02.10 Fracture of base of skull (closed)
0.669 0.331 0.000
E06 Thyroiditis
0.669 0.331 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.668 0.332 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.667 0.332 0.000
Y54.3 Benzothiadiazine derivatives
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.667 0.333 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.666 0.334 0.000
D66 Hereditary factor VIII deficiency
0.666 0.334 0.000
M71 Other bursopathies
0.666 0.334 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.666 0.334 0.000
S01.1 Open wound of eyelid and periocular area
0.666 0.334 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.666 0.334 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.666 0.334 0.000
T75 Effects of other external causes
0.665 0.334 0.000
Y40.0 Penicillins
0.665 0.335 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.665 0.335 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.665 0.335 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.664 0.336 0.000
E87.4 Mixed disorder of acid-base balance
0.663 0.337 0.000
M65.3 Trigger finger
0.663 0.337 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.663 0.337 0.000
X41.9 Unspecified place
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.662 0.338 0.000
M75.2 Bicipital tendinitis
0.662 0.338 0.000
V23.4 Driver injured in traffic accident
0.662 0.338 0.000
C32 Malignant neoplasm of larynx
0.661 0.338 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.661 0.339 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.661 0.339 0.000
H65-H75 Diseases of middle ear and mastoid
0.660 0.340 0.000
S00.9 Superficial injury of head, part unspecified
0.658 0.342 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.658 0.342 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.658 0.342 0.000
D68 Other coagulation defects
0.658 0.342 0.000
E14.8 With unspecified complications
0.658 0.342 0.000
E14.7 With multiple complications
0.658 0.342 0.000
E14.6 With other specified complications
0.658 0.342 0.000
E14.5 With peripheral circulatory complications
0.658 0.342 0.000
E14.4 With neurological complications
0.658 0.342 0.000
E14.2 Withrenal complications
0.658 0.342 0.000
E14.1 With ketoacidosis
0.658 0.342 0.000
E14.0 With coma
0.658 0.342 0.000
M43 Other deforming dorsopathies
0.658 0.342 0.000
E50-E64 Other nutritional deficiencies
0.657 0.343 0.000
B44.1 Other pulmonary aspergillosis
0.657 0.343 0.000
S80 Superficial injury of lower leg
0.657 0.343 0.000
T93.1 Sequelae of fracture of femur
0.654 0.346 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.654 0.346 0.000
M66 Spontaneous rupture of synovium and tendon
0.654 0.346 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.653 0.347 0.000
S89 Other and unspecified injuries of lower leg
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
S71 Open wound of hip and thigh
0.652 0.348 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.652 0.348 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.651 0.349 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.650 0.350 0.000
D22.5 Melanocytic naevi of trunk
0.650 0.350 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.650 0.350 0.000
E11.7 With multiple complications
0.650 0.350 0.000
E11.0 With coma
0.650 0.350 0.000
D73 Diseases of spleen
0.650 0.350 0.000
E13 Other specified diabetes mellitus
0.649 0.350 0.000
T23 Burn and corrosion of wrist and hand
0.649 0.351 0.000
E07 Other disorders of thyroid
0.649 0.351 0.000
B37.7 Candidal septicaemia
0.648 0.352 0.000
B37.6 Candidal endocarditis
0.648 0.352 0.000
B37.5 Candidal meningitis
0.648 0.352 0.000
B37.4 Candidiasis of other urogenital sites
0.648 0.352 0.000
B37.2 Candidiasis of skin and nail
0.648 0.352 0.000
E10.3 With ophthalmic complications
0.646 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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