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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79802820
log Bayes Factor = 18.8126
Chromosome 1   position 216,046,129  (GRCh37) Explore rs79802820 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Z45 Adjustment and management of implanted device
0.998 0.002 0.000
Z51 Other medical care
0.997 0.003 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
G20-G26 Extrapyramidal and movement disorders
0.992 0.008 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.990 0.010 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
H53-H54 Visual disturbances and blindness
0.978 0.022 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.975 0.025 0.000
M13 Other arthritis
0.974 0.026 0.000
H53 Visual disturbances
0.969 0.031 0.000
M23 Internal derangement of knee
0.969 0.031 0.000
Z51.0 Radiotherapy session
0.968 0.032 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.962 0.038 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.962 0.038 0.000
G20 Parkinson's disease
0.961 0.039 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.960 0.040 0.000
M86-M90 Other osteopathies
0.959 0.041 0.000
Z45.8 Adjustment and management of other implanted devices
0.959 0.041 0.000
M13.9 Arthritis, unspecified
0.957 0.043 0.000
H53.8 Other visual disturbances
0.956 0.044 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.954 0.046 0.000
Z45.2 Adjustment and management of vascular access device
0.952 0.048 0.000
M80-M85 Disorders of bone density and structure
0.951 0.049 0.000
Chapter II Neoplasms
0.951 0.049 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.948 0.052 0.000
B95-B98 Bacterial, viral and other infectious agents
0.946 0.054 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.941 0.059 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.935 0.065 0.000
A30-A49 Other bacterial diseases
0.933 0.067 0.000
M21 Other acquired deformities of limbs
0.933 0.067 0.000
Chapter V Mental and behavioural disorders
0.930 0.070 0.000
Z48 Other surgical follow-up care
0.928 0.072 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.928 0.072 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.925 0.075 0.000
M10 Gout
0.924 0.076 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.921 0.079 0.000
Z86 Personal history of certain other diseases
0.915 0.085 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.912 0.088 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.911 0.089 0.000
M50-M54 Other dorsopathies
0.910 0.090 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.908 0.092 0.000
G25 Other extrapyramidal and movement disorders
0.907 0.093 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.906 0.094 0.000
Y52 Agents primarily affecting the cardiovascular system
0.902 0.098 0.000
T93 Sequelae of injuries of lower limb
0.901 0.099 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.901 0.099 0.000
M89 Other disorders of bone
0.899 0.101 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.893 0.107 0.000
Z80 Family history of malignant neoplasm
0.892 0.108 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.891 0.109 0.000
T39.1 4-Aminophenol derivatives
0.890 0.110 0.000
Chapter XI Diseases of the digestive system
0.890 0.110 0.000
Z89 Acquired absence of limb
0.888 0.112 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.885 0.115 0.000
S10-S19 Injuries to the neck
0.885 0.115 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.884 0.116 0.000
A41 Other septicaemia
0.884 0.116 0.000
Z86.4 Personal history of psychoactive substance abuse
0.884 0.116 0.000
L98.0 Pyogenic granuloma
0.880 0.120 0.000
G40-G47 Episodic and paroxysmal disorders
0.879 0.121 0.000
Z51.3 Blood transfusion without reported diagnosis
0.878 0.122 0.000
T66-T78 Other and unspecified effects of external causes
0.878 0.122 0.000
M86 Osteomyelitis
0.876 0.124 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.876 0.124 0.000
C34 Malignant neoplasm of bronchus and lung
0.876 0.124 0.000
M45-M49 Spondylopathies
0.874 0.126 0.000
Z48.8 Other specified surgical follow-up care
0.873 0.127 0.000
M10.9 Gout, unspecified
0.872 0.128 0.000
Z43 Attention to artificial openings
0.872 0.128 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.871 0.129 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.866 0.134 0.000
L82 Seborrhoeic keratosis
0.864 0.136 0.000
A41.9 Septicaemia, unspecified
0.863 0.137 0.000
M84 Disorders of continuity of bone
0.862 0.138 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.862 0.138 0.000
F41 Other anxiety disorders
0.861 0.139 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.859 0.141 0.000
Z51.8 Other specified medical care
0.859 0.141 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.859 0.141 0.000
H54 Blindness and low vision
0.858 0.141 0.000
L20-L30 Dermatitis and eczema
0.857 0.143 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.853 0.147 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.853 0.147 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.852 0.148 0.000
S70-S79 Injuries to the hip and thigh
0.851 0.149 0.000
M35 Other systemic involvement of connective tissue
0.850 0.150 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.850 0.150 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.850 0.150 0.000
H53.4 Visual field defects
0.849 0.151 0.000
G24 Dystonia
0.847 0.153 0.000
X60-X84 Intentional self-harm
0.847 0.153 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.845 0.155 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.844 0.156 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.842 0.158 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.841 0.159 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.840 0.160 0.000
K81 Cholecystitis
0.840 0.160 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.839 0.161 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.837 0.163 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.836 0.164 0.000
M25 Other joint disorders, not elsewhere classified
0.836 0.164 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.835 0.165 0.000
M10.99 Gout, unspecified (Site unspecified)
0.835 0.165 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.834 0.166 0.000
C15-C26 Malignant neoplasms of digestive organs
0.832 0.168 0.000
Y43 Primarily systemic agents
0.832 0.168 0.000
T92 Sequelae of injuries of upper limb
0.831 0.169 0.000
K65-K67 Diseases of peritoneum
0.830 0.170 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.829 0.171 0.000
Z49 Care involving dialysis
0.829 0.171 0.000
C43 Malignant melanoma of skin
0.828 0.172 0.000
C34.9 Bronchus or lung, unspecified
0.827 0.173 0.000
Z45.1 Adjustment and management of infusion pump
0.826 0.174 0.000
Z97 Presence of other devices
0.825 0.175 0.000
Q60-Q64 Congenital malformations of the urinary system
0.819 0.181 0.000
Z51.9 Medical care, unspecified
0.819 0.181 0.000
L03 Cellulitis
0.819 0.181 0.000
M11 Other crystal arthropathies
0.817 0.183 0.000
K86 Other diseases of pancreas
0.817 0.183 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.817 0.183 0.000
D60-D64 Aplastic and other anaemias
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.813 0.187 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.812 0.188 0.000
Z88.2 Personal history of allergy to sulphonamides
0.812 0.188 0.000
M89.9 Disorder of bone, unspecified
0.812 0.188 0.000
M85 Other disorders of bone density and structure
0.811 0.189 0.000
T98 Sequelae of other and unspecified effects of external causes
0.811 0.189 0.000
Q00-Q07 Congenital malformations of the nervous system
0.807 0.193 0.000
K81.0 Acute cholecystitis
0.807 0.193 0.000
T78 Adverse effects, not elsewhere classified
0.807 0.193 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.806 0.194 0.000
K55-K64 Other diseases of intestines
0.806 0.194 0.000
M07 Psoriatic and enteropathic arthropathies
0.805 0.195 0.000
L08 Other local infections of skin and subcutaneous tissue
0.805 0.195 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.805 0.195 0.000
Z80.3 Family history of malignant neoplasm of breast
0.803 0.197 0.000
K65 Peritonitis
0.801 0.199 0.000
M21.2 Flexion deformity
0.801 0.199 0.000
Z50 Care involving use of rehabilitation procedures
0.800 0.200 0.000
M86.9 Osteomyelitis, unspecified
0.800 0.200 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.799 0.201 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.798 0.202 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.796 0.204 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
H52 Disorders of refraction and accommodation
0.794 0.206 0.000
L05 Pilonidal cyst
0.794 0.206 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.794 0.206 0.000
M60-M63 Disorders of muscles
0.793 0.206 0.000
M89.0 Algoneurodystrophy
0.793 0.207 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.793 0.207 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.793 0.207 0.000
Z44 Fitting and adjustment of external prosthetic device
0.793 0.207 0.000
G30-G32 Other degenerative diseases of the nervous system
0.792 0.207 0.000
Z54 Convalescence
0.792 0.208 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.792 0.208 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.791 0.209 0.000
V40-V49 Car occupant injured in transport accident
0.790 0.210 0.000
B99-B99 Other infectious diseases
0.790 0.210 0.000
L84 Corns and callosities
0.789 0.211 0.000
M50 Cervical disk disorders
0.785 0.215 0.000
H10-H13 Disorders of conjunctiva
0.783 0.217 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.782 0.218 0.000
M34 Systemic sclerosis
0.782 0.218 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.781 0.218 0.000
Y86 Sequelae of other accidents
0.781 0.219 0.000
F43 Reaction to severe stress, and adjustment disorders
0.780 0.220 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.780 0.220 0.000
L40-L45 Papulosquamous disorders
0.779 0.221 0.000
K62 Other diseases of anus and rectum
0.779 0.221 0.000
Z48.0 Attention to surgical dressings and sutures
0.778 0.221 0.000
G70-G73 Diseases of myoneural junction and muscle
0.778 0.222 0.000
L10-L14 Bullous disorders
0.778 0.222 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.777 0.223 0.000
H53.9 Visual disturbance, unspecified
0.776 0.224 0.000
M22 Disorders of patella
0.775 0.224 0.000
T90 Sequelae of injuries of head
0.775 0.225 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.775 0.225 0.000
M14 Arthropathies in other diseases classified elsewhere
0.771 0.229 0.000
G40 Epilepsy
0.770 0.230 0.000
M23.0 Cystic meniscus
0.770 0.230 0.000
L85 Other epidermal thickening
0.769 0.231 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.767 0.233 0.000
V80-V89 Other land transport accidents
0.767 0.233 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.766 0.233 0.000
K61 Abscess of anal and rectal regions
0.765 0.235 0.000
K50-K52 Noninfective enteritis and colitis
0.765 0.235 0.000
M31 Other necrotising vasculopathies
0.763 0.237 0.000
B25-B34 Other viral diseases
0.763 0.237 0.000
M45 Ankylosing spondylitis
0.762 0.238 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.762 0.238 0.000
M21.1 Varus deformity, not elsewhere classified
0.761 0.239 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.759 0.241 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.758 0.242 0.000
T93.2 Sequelae of other fractures of lower limb
0.758 0.242 0.000
K62.8 Other specified diseases of anus and rectum
0.757 0.243 0.000
Z81 Family history of mental and behavioural disorders
0.756 0.244 0.000
D75 Other diseases of blood and blood-forming organs
0.756 0.244 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.754 0.246 0.000
H54.4 Blindness, one eye
0.753 0.247 0.000
C81 Hodgkin's disease
0.753 0.247 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.753 0.247 0.000
L94 Other localised connective tissue disorders
0.753 0.247 0.000
Z89.5 Acquired absence of leg at or below knee
0.753 0.247 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.752 0.248 0.000
L03.3 Cellulitis of trunk
0.752 0.248 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.751 0.249 0.000
M06 Other rheumatoid arthritis
0.751 0.249 0.000
Y45.0 Opioids and related analgesics
0.749 0.251 0.000
Z89.6 Acquired absence of leg above knee
0.748 0.251 0.000
K61.0 Anal abscess
0.748 0.252 0.000
H43-H45 Disorders of vitreous body and globe
0.747 0.253 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.746 0.254 0.000
L27 Dermatitis due to substances taken internally
0.746 0.254 0.000
M23.9 Internal derangement of knee, unspecified
0.746 0.254 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.745 0.255 0.000
S12 Fracture of neck
0.744 0.256 0.000
Z51.2 Other chemotherapy
0.744 0.256 0.000
G24.9 Dystonia, unspecified
0.743 0.257 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.742 0.258 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.742 0.258 0.000
H49 Paralytic strabismus
0.742 0.258 0.000
C15 Malignant neoplasm of oesophagus
0.741 0.259 0.000
M23.5 Chronic instability of knee
0.740 0.260 0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.740 0.260 0.000
H50 Other strabismus
0.739 0.261 0.000
B35-B49 Mycoses
0.737 0.263 0.000
G81 Hemiplegia
0.736 0.264 0.000
A49 Bacterial infection of unspecified site
0.735 0.265 0.000
D80-D89 Certain disorders involving the immune mechanism
0.734 0.266 0.000
W20-W49 Exposure to inanimate mechanical forces
0.733 0.267 0.000
W50-W64 Exposure to animate mechanical forces
0.732 0.268 0.000
D63.0 Anaemia in neoplastic disease
0.732 0.268 0.000
G44 Other headache syndromes
0.731 0.269 0.000
Z91.5 Personal history of self-harm
0.731 0.269 0.000
M21.4 Flat foot [pes planus] (acquired)
0.731 0.269 0.000
S50-S59 Injuries to the elbow and forearm
0.731 0.269 0.000
Z40 Prophylactic surgery
0.730 0.270 0.000
T00-T07 Injuries involving multiple body regions
0.730 0.270 0.000
M50.3 Other cervical disk degeneration
0.730 0.270 0.000
X20-X29 Contact with venomous animals and plants
0.730 0.270 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.730 0.270 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
M54 Dorsalgia
0.729 0.271 0.000
K65.0 Acute peritonitis
0.729 0.271 0.000
H53.0 Amblyopia ex anopsia
0.728 0.272 0.000
M21.6 Other acquired deformities of ankle and foot
0.727 0.273 0.000
L29 Pruritus
0.727 0.273 0.000
C34.3 Lower lobe, bronchus or lung
0.726 0.274 0.000
M48 Other spondylopathies
0.725 0.275 0.000
C90.0 Multiple myeloma
0.725 0.275 0.000
Z89.4 Acquired absence of foot and ankle
0.724 0.276 0.000
A48 Other bacterial diseases, not elsewhere classified
0.724 0.276 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.723 0.277 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.723 0.277 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.723 0.277 0.000
L83 Acanthosis nigricans
0.722 0.278 0.000
M13.93 Arthritis, unspecified (Forearm)
0.721 0.278 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.721 0.279 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.721 0.279 0.000
G25.3 Myoclonus
0.720 0.280 0.000
K80 Cholelithiasis
0.720 0.280 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.720 0.280 0.000
Z43.2 Attention to ileostomy
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.716 0.284 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.716 0.284 0.000
L93 Lupus erythematosus
0.716 0.284 0.000
L87 Transepidermal elimination disorders
0.716 0.284 0.000
L88 Pyoderma gangrenosum
0.716 0.284 0.000
L86 Keratoderma in diseases classified elsewhere
0.716 0.284 0.000
L80 Vitiligo
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
F40 Phobic anxiety disorders
0.716 0.284 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.716 0.284 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.716 0.284 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.715 0.285 0.000
Z45.3 Adjustment and management of implanted hearing device
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.715 0.285 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.715 0.285 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.715 0.285 0.000
L98.5 Mucinosis of skin
0.715 0.285 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.715 0.285 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.715 0.285 0.000
L98.1 Factitial dermatitis
0.715 0.285 0.000
M13.0 Polyarthritis, unspecified
0.715 0.285 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
K62.6 Ulcer of anus and rectum
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
M33 Dermatopolymyositis
0.713 0.286 0.000
M32 Systemic lupus erythematosus
0.713 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.286 0.000
M82 Osteoporosis in diseases classified elsewhere
0.713 0.287 0.000
K86.8 Other specified diseases of pancreas
0.713 0.287 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
L03.0 Cellulitis of finger and toe
0.711 0.289 0.000
G23 Other degenerative diseases of basal ganglia
0.711 0.289 0.000
G21 Secondary Parkinsonism
0.711 0.289 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.711 0.289 0.000
G22 Parkinsonism in diseases classified elsewhere
0.711 0.289 0.000
G43 Migraine
0.710 0.290 0.000
Q61 Cystic kidney disease
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.708 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
M51 Other intervertebral disk disorders
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.707 0.293 0.000
M35.1 Other overlap syndromes
0.707 0.293 0.000
M80 Osteoporosis with pathological fracture
0.707 0.293 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.707 0.293 0.000
T09 Other injuries of spine and trunk, level unspecified
0.706 0.294 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.706 0.294 0.000
M91-M94 Chondropathies
0.705 0.295 0.000
G90-G99 Other disorders of the nervous system
0.705 0.295 0.000
T92.1 Sequelae of fracture of arm
0.704 0.296 0.000
Z43.3 Attention to colostomy
0.704 0.296 0.000
Q05 Spina bifida
0.703 0.297 0.000
Z03.8 Observation for other suspected diseases and conditions
0.703 0.297 0.000
F41.2 Mixed anxiety and depressive disorder
0.703 0.297 0.000
A41.8 Other specified septicaemia
0.702 0.298 0.000
L05.9 Pilonidal cyst without abscess
0.702 0.298 0.000
C71 Malignant neoplasm of brain
0.701 0.299 0.000
H18 Other disorders of cornea
0.701 0.299 0.000
S20-S29 Injuries to the thorax
0.700 0.300 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.700 0.300 0.000
K65.9 Peritonitis, unspecified
0.699 0.301 0.000
K86.1 Other chronic pancreatitis
0.699 0.301 0.000
T95 Sequelae of burns, corrosions and frostbite
0.699 0.301 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.699 0.301 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.699 0.301 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.699 0.301 0.000
M13.8 Other specified arthritis
0.698 0.302 0.000
M13.1 Monoarthritis, not elsewhere classified
0.698 0.302 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.698 0.302 0.000
Y43.1 Antineoplastic antimetabolites
0.698 0.302 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.698 0.302 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.697 0.303 0.000
Z50.1 Other physical therapy
0.697 0.303 0.000
M81 Osteoporosis without pathological fracture
0.697 0.303 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.697 0.303 0.000
Z52 Donors of organs and tissues
0.696 0.304 0.000
M25.7 Osteophyte
0.696 0.304 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.696 0.304 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.696 0.304 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.695 0.305 0.000
H53.6 Night blindness
0.695 0.305 0.000
H53.5 Colour vision deficiencies
0.695 0.305 0.000
H53.3 Other disorders of binocular vision
0.695 0.305 0.000
M23.1 Discoid meniscus (congenital)
0.695 0.305 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.694 0.306 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.694 0.306 0.000
Z43.1 Attention to gastrostomy
0.693 0.307 0.000
L03.8 Cellulitis of other sites
0.693 0.307 0.000
C15.5 Lower third of oesophagus
0.693 0.307 0.000
H53.1 Subjective visual disturbances
0.692 0.307 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.692 0.308 0.000
K82 Other diseases of gallbladder
0.691 0.309 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.690 0.310 0.000
Z97.4 Presence of external hearing-aid
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.690 0.310 0.000
M00-M03 Infectious arthropathies
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.689 0.311 0.000
Y59 Other and unspecified vaccines and biological substances
0.689 0.311 0.000
Y58 Bacterial vaccines
0.689 0.311 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.689 0.311 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.689 0.311 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.689 0.311 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.689 0.311 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.689 0.311 0.000
Y48 Anaesthetics and therapeutic gases
0.689 0.311 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.689 0.311 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.689 0.311 0.000
Y89 Sequelae of other external causes
0.689 0.311 0.000
M11.2 Other chondrocalcinosis
0.688 0.312 0.000
M35.3 Polymyalgia rheumatica
0.688 0.312 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.688 0.312 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.687 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
G81.9 Hemiplegia, unspecified
0.687 0.313 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
C23 Malignant neoplasm of gallbladder
0.686 0.314 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.686 0.314 0.000
Y45.2 Propionic acid derivatives
0.684 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
M21.3 Wrist or foot drop (acquired)
0.684 0.316 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.683 0.317 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.683 0.317 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
M86.6 Other chronic osteomyelitis
0.682 0.318 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.682 0.318 0.000
H20 Iridocyclitis
0.682 0.318 0.000
M83 Adult osteomalacia
0.682 0.318 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.682 0.318 0.000
L90 Atrophic disorders of skin
0.682 0.318 0.000
Z83 Family history of other specific disorders
0.682 0.318 0.000
C64-C68 Malignant neoplasms of urinary tract
0.682 0.318 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.682 0.318 0.000
Z80.6 Family history of leukaemia
0.681 0.319 0.000
T14 Injury of unspecified body region
0.681 0.319 0.000
X59 Exposure to unspecified factor
0.681 0.319 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.680 0.320 0.000
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
Z51.5 Palliative care
0.680 0.320 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.679 0.321 0.000
Z84 Family history of other conditions
0.679 0.321 0.000
M89.04 Algoneurodystrophy (Hand)
0.677 0.323 0.000
T78.2 Anaphylactic shock, unspecified
0.677 0.323 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.676 0.323 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.676 0.324 0.000
Q80-Q89 Other congenital malformations
0.676 0.324 0.000
Z42 Follow-up care involving plastic surgery
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.675 0.325 0.000
Z88.5 Personal history of allergy to narcotic agent
0.675 0.325 0.000
M84.4 Pathological fracture, not elsewhere classified
0.674 0.326 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.674 0.326 0.000
T39.4 Antirheumatics, not elsewhere classified
0.674 0.326 0.000
T39.2 Pyrazolone derivatives
0.674 0.326 0.000
F43.2 Adjustment disorders
0.674 0.326 0.000
X78 Intentional self-harm by sharp object
0.674 0.326 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.673 0.327 0.000
M90 Osteopathies in diseases classified elsewhere
0.673 0.327 0.000
Z47 Other orthopaedic follow-up care
0.673 0.327 0.000
Y85 Sequelae of transport accidents
0.673 0.327 0.000
T91 Sequelae of injuries of neck and trunk
0.672 0.327 0.000
Z51.1 Chemotherapy session for neoplasm
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
M53 Other dorsopathies, not elsewhere classified
0.670 0.330 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.670 0.330 0.000
C34.0 Main bronchus
0.670 0.330 0.000
Z12 Special screening examination for neoplasms
0.670 0.330 0.000
A44 Bartonellosis
0.669 0.331 0.000
A43 Nocardiosis
0.669 0.331 0.000
A42 Actinomycosis
0.669 0.331 0.000
A40 Streptococcal septicaemia
0.669 0.331 0.000
A39 Meningococcal infection
0.669 0.331 0.000
A37 Whooping cough
0.669 0.331 0.000
A36 Diphtheria
0.669 0.331 0.000
A32 Listeriosis
0.669 0.331 0.000
A31 Infection due to other mycobacteria
0.669 0.331 0.000
A30 Leprosy [Hansen's disease]
0.669 0.331 0.000
A38 Scarlet fever
0.669 0.331 0.000
A35 Other tetanus
0.669 0.331 0.000
A34 Obstetrical tetanus
0.669 0.331 0.000
A33 Tetanus neonatorum
0.669 0.331 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.669 0.331 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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