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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79851078
log Bayes Factor = 5.58339
Chromosome 17   position 30,005,058  (GRCh37) Explore rs79851078 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
I67 Other cerebrovascular diseases
1.000 0.000 0.000
I67.9 Cerebrovascular disease, unspecified
0.999 0.001 0.000
# Top node
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
I25 Chronic ischaemic heart disease
0.990 0.010 0.000
I47 Paroxysmal tachycardia
0.988 0.012 0.000
I05-I09 Chronic rheumatic heart diseases
0.976 0.024 0.000
I67.8 Other specified cerebrovascular diseases
0.973 0.027 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
I25.2 Old myocardial infarction
0.958 0.042 0.000
I47.2 Ventricular tachycardia
0.951 0.049 0.000
O60-O75 Complications of labour and delivery
0.948 0.052 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.946 0.054 0.000
I25.5 Ischaemic cardiomyopathy
0.945 0.055 0.000
I69 Sequelae of cerebrovascular disease
0.945 0.055 0.000
I47.1 Supraventricular tachycardia
0.938 0.062 0.000
H02 Other disorders of eyelid
0.938 0.062 0.000
H02.9 Disorder of eyelid, unspecified
0.927 0.073 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.926 0.074 0.000
I51 Complications and ill-defined descriptions of heart disease
0.919 0.081 0.000
I07 Rheumatic tricuspid valve diseases
0.911 0.089 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.904 0.096 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.903 0.097 0.000
I21 Acute myocardial infarction
0.899 0.101 0.000
I08 Multiple valve diseases
0.898 0.102 0.000
I49 Other cardiac arrhythmias
0.892 0.108 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.892 0.108 0.000
O63 Long labour
0.890 0.110 0.000
H43-H45 Disorders of vitreous body and globe
0.888 0.112 0.000
O20 Haemorrhage in early pregnancy
0.887 0.113 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.875 0.125 0.000
I49.9 Cardiac arrhythmia, unspecified
0.873 0.127 0.000
I38 Endocarditis, valve unspecified
0.872 0.128 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.870 0.130 0.000
M20-M25 Other joint disorders
0.867 0.133 0.000
H02.4 Ptosis of eyelid
0.865 0.135 0.000
I07.1 Tricuspid insufficiency
0.865 0.135 0.000
G90-G99 Other disorders of the nervous system
0.863 0.137 0.000
G81 Hemiplegia
0.860 0.140 0.000
O00-O08 Pregnancy with abortive outcome
0.854 0.146 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.847 0.153 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.846 0.154 0.000
H18 Other disorders of cornea
0.846 0.154 0.000
M05-M14 Inflammatory polyarthropathies
0.845 0.155 0.000
I51.7 Cardiomegaly
0.841 0.159 0.000
O72 Postpartum haemorrhage
0.837 0.163 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.835 0.165 0.000
I25.1 Atherosclerotic heart disease
0.833 0.167 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.829 0.171 0.000
Chapter I Certain infectious and parasitic diseases
0.828 0.172 0.000
G81.9 Hemiplegia, unspecified
0.828 0.172 0.000
M25 Other joint disorders, not elsewhere classified
0.823 0.177 0.000
O80-O84 Delivery
0.823 0.177 0.000
I22 Subsequent myocardial infarction
0.822 0.178 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.820 0.180 0.000
I21.4 Acute subendocardial myocardial infarction
0.819 0.181 0.000
M06 Other rheumatoid arthritis
0.818 0.182 0.000
H43 Disorders of vitreous body
0.816 0.184 0.000
I69.3 Sequelae of cerebral infarction
0.816 0.184 0.000
O63.1 Prolonged second stage (of labour)
0.815 0.185 0.000
M24 Other specific joint derangements
0.815 0.185 0.000
S00-S09 Injuries to the head
0.815 0.185 0.000
O63.9 Long labour, unspecified
0.813 0.187 0.000
I33 Acute and subacute endocarditis
0.811 0.189 0.000
M86-M90 Other osteopathies
0.807 0.193 0.000
I45 Other conduction disorders
0.805 0.195 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.804 0.196 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.801 0.199 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.795 0.205 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.792 0.208 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.791 0.209 0.000
I50 Heart failure
0.790 0.210 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.787 0.213 0.000
S00 Superficial injury of head
0.786 0.214 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.783 0.217 0.000
H30-H36 Disorders of choroid and retina
0.781 0.219 0.000
H25-H28 Disorders of lens
0.780 0.220 0.000
O70 Perineal laceration during delivery
0.778 0.222 0.000
H40-H42 Glaucoma
0.777 0.223 0.000
H20 Iridocyclitis
0.776 0.224 0.000
I36 Nonrheumatic tricuspid valve disorders
0.775 0.225 0.000
M00-M03 Infectious arthropathies
0.772 0.228 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.771 0.229 0.000
I47.0 Reentry ventricular arrhythmia
0.770 0.230 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.765 0.235 0.000
Q60-Q64 Congenital malformations of the urinary system
0.764 0.236 0.000
I30 Acute pericarditis
0.764 0.236 0.000
G93 Other disorders of brain
0.761 0.239 0.000
I25.4 Coronary artery aneurysm
0.760 0.240 0.000
O73 Retained placenta and membranes, without haemorrhage
0.759 0.241 0.000
S00.9 Superficial injury of head, part unspecified
0.757 0.243 0.000
I37 Pulmonary valve disorders
0.756 0.244 0.000
M06.9 Rheumatoid arthritis, unspecified
0.755 0.245 0.000
I25.3 Aneurysm of heart
0.754 0.245 0.000
O26.9 Pregnancy-related condition, unspecified
0.752 0.248 0.000
H02.6 Xanthelasma of eyelid
0.750 0.250 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.750 0.250 0.000
B95-B98 Bacterial, viral and other infectious agents
0.748 0.252 0.000
O23 Infections of genito-urinary tract in pregnancy
0.745 0.255 0.000
I67.2 Cerebral atherosclerosis
0.745 0.255 0.000
G83 Other paralytic syndromes
0.744 0.256 0.000
O20.8 Other haemorrhage in early pregnancy
0.740 0.260 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.740 0.260 0.000
I09 Other rheumatic heart diseases
0.738 0.262 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
H02.1 Ectropion of eyelid
0.734 0.265 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.733 0.267 0.000
H18.9 Disorder of cornea, unspecified
0.733 0.267 0.000
M06.0 Seronegative rheumatoid arthritis
0.732 0.268 0.000
M25.8 Other specified joint disorders
0.731 0.269 0.000
H43.1 Vitreous haemorrhage
0.730 0.270 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.729 0.271 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.728 0.272 0.000
M23 Internal derangement of knee
0.726 0.274 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.724 0.275 0.000
I51.9 Heart disease, unspecified
0.724 0.276 0.000
O03 Spontaneous abortion
0.724 0.276 0.000
S01 Open wound of head
0.721 0.279 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.720 0.280 0.000
M24.0 Loose body in joint
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.717 0.283 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.717 0.283 0.000
I67.5 Moyamoya disease
0.717 0.283 0.000
I67.4 Hypertensive encephalopathy
0.717 0.283 0.000
I67.3 Progressive vascular leukoencephalopathy
0.717 0.283 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.715 0.285 0.000
E00-E07 Disorders of thyroid gland
0.715 0.285 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
G62 Other polyneuropathies
0.714 0.286 0.000
M89 Other disorders of bone
0.714 0.286 0.000
H18.4 Corneal degeneration
0.713 0.286 0.000
O26.2 Pregnancy care of habitual aborter
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
O04 Medical abortion
0.712 0.288 0.000
H02.0 Entropion and trichiasis of eyelid
0.712 0.288 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.710 0.290 0.000
M22 Disorders of patella
0.710 0.290 0.000
O21 Excessive vomiting in pregnancy
0.709 0.290 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.709 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
O72.0 Third-stage haemorrhage
0.707 0.293 0.000
S80-S89 Injuries to the knee and lower leg
0.705 0.295 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.705 0.295 0.000
M25.7 Osteophyte
0.705 0.295 0.000
I51.8 Other ill-defined heart diseases
0.703 0.297 0.000
H43.9 Disorder of vitreous body, unspecified
0.702 0.298 0.000
E07 Other disorders of thyroid
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.700 0.300 0.000
I06 Rheumatic aortic valve diseases
0.700 0.300 0.000
O62 Abnormalities of forces of labour
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
I67.1 Cerebral aneurysm, nonruptured
0.694 0.305 0.000
I50.0 Congestive heart failure
0.694 0.306 0.000
I63 Cerebral infarction
0.693 0.307 0.000
M25.3 Other instability of joint
0.691 0.309 0.000
O29 Complications of anaesthesia during pregnancy
0.690 0.310 0.000
O28 Abnormal findings on antenatal screening of mother
0.690 0.310 0.000
O22 Venous complications in pregnancy
0.690 0.310 0.000
O25 Malnutrition in pregnancy
0.690 0.310 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.690 0.310 0.000
H21 Other disorders of iris and ciliary body
0.687 0.313 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.687 0.313 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.686 0.314 0.000
M00 Pyogenic arthritis
0.686 0.314 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.685 0.315 0.000
I45.5 Other specified heart block
0.684 0.316 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.681 0.319 0.000
O81 Single delivery by forceps and vacuum extractor
0.680 0.320 0.000
O74 Complications of anaesthesia during labour and delivery
0.679 0.321 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.679 0.321 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.679 0.321 0.000
O60 Preterm delivery
0.679 0.321 0.000
I33.0 Acute and subacute infective endocarditis
0.679 0.321 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.678 0.321 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.678 0.322 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.678 0.322 0.000
I05 Rheumatic mitral valve diseases
0.678 0.322 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.677 0.322 0.000
I62 Other nontraumatic intracranial haemorrhage
0.675 0.325 0.000
O26.8 Other specified pregnancy-related conditions
0.675 0.325 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.675 0.325 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.675 0.325 0.000
O70.0 First degree perineal laceration during delivery
0.673 0.327 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.672 0.328 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.672 0.328 0.000
H02.2 Lagophthalmos
0.672 0.328 0.000
S10-S19 Injuries to the neck
0.671 0.328 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.671 0.329 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
E07.9 Disorder of thyroid, unspecified
0.670 0.330 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.670 0.330 0.000
G40-G47 Episodic and paroxysmal disorders
0.669 0.331 0.000
H35 Other retinal disorders
0.667 0.333 0.000
M34 Systemic sclerosis
0.667 0.333 0.000
H05 Disorders of orbit
0.665 0.335 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.664 0.336 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.664 0.336 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.664 0.336 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.664 0.336 0.000
H17 Corneal scars and opacities
0.664 0.336 0.000
H15 Disorders of sclera
0.664 0.336 0.000
O66 Other obstructed labour
0.663 0.337 0.000
E16 Other disorders of pancreatic internal secretion
0.662 0.338 0.000
O03.4 Incomplete, without complication
0.662 0.338 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.661 0.338 0.000
M60-M63 Disorders of muscles
0.661 0.339 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
I51.5 Myocardial degeneration
0.659 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.659 0.341 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.659 0.341 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.659 0.341 0.000
I51.0 Cardiac septal defect, acquired
0.659 0.341 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.659 0.341 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
M86 Osteomyelitis
0.658 0.342 0.000
I51.4 Myocarditis, unspecified
0.658 0.342 0.000
G82 Paraplegia and tetraplegia
0.656 0.344 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
O82 Single delivery by Caesarean section
0.656 0.344 0.000
O71 Other obstetric trauma
0.655 0.345 0.000
I07.9 Tricuspid valve disease, unspecified
0.653 0.347 0.000
I07.8 Other tricuspid valve diseases
0.653 0.347 0.000
I07.2 Tricuspid stenosis with insufficiency
0.653 0.347 0.000
I07.0 Tricuspid stenosis
0.653 0.347 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.653 0.347 0.000
G90 Disorders of autonomic nervous system
0.653 0.347 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.653 0.347 0.000
M07 Psoriatic and enteropathic arthropathies
0.652 0.348 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.652 0.348 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.651 0.348 0.000
Chapter V Mental and behavioural disorders
0.650 0.350 0.000
H25 Senile cataract
0.650 0.350 0.000
M24.2 Disorder of ligament
0.649 0.351 0.000
Q00-Q07 Congenital malformations of the nervous system
0.649 0.351 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.649 0.351 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.648 0.352 0.000
S00.8 Superficial injury of other parts of head
0.647 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
Chapter XXII Codes for special purposes
0.647 0.353 0.000
S01.2 Open wound of nose
0.646 0.354 0.000
H36 Retinal disorders in diseases classified elsewhere
0.646 0.354 0.000
M24.6 Ankylosis of joint
0.645 0.355 0.000
A65-A69 Other spirochaetal diseases
0.645 0.355 0.000
I46 Cardiac arrest
0.644 0.355 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.644 0.356 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.644 0.356 0.000
E10-E14 Diabetes mellitus
0.644 0.356 0.000
I08.9 Multiple valve disease, unspecified
0.644 0.356 0.000
I49.5 Sick sinus syndrome
0.642 0.357 0.000
H20.9 Iridocyclitis, unspecified
0.642 0.358 0.000
I49.2 Junctional premature depolarisation
0.640 0.360 0.000
E20-E35 Disorders of other endocrine glands
0.640 0.360 0.000
H30 Chorioretinal inflammation
0.639 0.361 0.000
S40-S49 Injuries to the shoulder and upper arm
0.639 0.361 0.000
H18.8 Other specified disorders of cornea
0.639 0.361 0.000
M91-M94 Chondropathies
0.639 0.361 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.638 0.362 0.000
H55-H59 Other disorders of eye and adnexa
0.637 0.362 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.637 0.363 0.000
M25.84 Other specified joint disorders (Hand)
0.637 0.363 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.637 0.363 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.636 0.364 0.000
M25.78 Osteophyte (Other)
0.636 0.364 0.000
H00 Hordeolum and chalazion
0.636 0.364 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.635 0.365 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.634 0.366 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.633 0.367 0.000
M23.8 Other internal derangements of knee
0.632 0.368 0.000
I49.4 Other and unspecified premature depolarisation
0.631 0.369 0.000
S01.8 Open wound of other parts of head
0.630 0.370 0.000
E07.8 Other specified disorders of thyroid
0.630 0.370 0.000
H10-H13 Disorders of conjunctiva
0.629 0.371 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.628 0.372 0.000
M24.07 Loose body in joint (Ankle and foot)
0.628 0.372 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.627 0.372 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.627 0.373 0.000
O26.5 Maternal hypotension syndrome
0.627 0.373 0.000
O26.4 Herpes gestationis
0.627 0.373 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.627 0.373 0.000
O26.1 Low weight gain in pregnancy
0.627 0.373 0.000
O26.0 Excessive weight gain in pregnancy
0.627 0.373 0.000
G96 Other disorders of central nervous system
0.627 0.373 0.000
I45.6 Preexcitation syndrome
0.626 0.373 0.000
I45.3 Trifascicular block
0.626 0.374 0.000
I51.6 Cardiovascular disease, unspecified
0.626 0.374 0.000
M35 Other systemic involvement of connective tissue
0.626 0.374 0.000
Q80-Q89 Other congenital malformations
0.626 0.374 0.000
H44 Disorders of globe
0.625 0.375 0.000
O73.0 Retained placenta, without haemorrhage
0.624 0.376 0.000
G93.0 Cerebral cysts
0.624 0.376 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.624 0.376 0.000
G62.9 Polyneuropathy, unspecified
0.624 0.376 0.000
M00.9 Pyogenic arthritis, unspecified
0.624 0.376 0.000
M80-M85 Disorders of bone density and structure
0.624 0.376 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.624 0.376 0.000
M22.2 Patellofemoral disorders
0.623 0.377 0.000
I45.4 Nonspecific intraventricular block
0.622 0.378 0.000
M65-M68 Disorders of synovium and tendon
0.622 0.378 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.622 0.378 0.000
M33 Dermatopolymyositis
0.622 0.378 0.000
M32 Systemic lupus erythematosus
0.622 0.378 0.000
M30 Polyarteritis nodosa and related conditions
0.622 0.378 0.000
H40 Glaucoma
0.622 0.378 0.000
A15-A19 Tuberculosis
0.621 0.379 0.000
G40 Epilepsy
0.620 0.380 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.620 0.380 0.000
B65-B83 Helminthiases
0.620 0.380 0.000
G37 Other demyelinating diseases of central nervous system
0.620 0.380 0.000
H47.1 Papilloedema, unspecified
0.620 0.380 0.000
G83.9 Paralytic syndrome, unspecified
0.619 0.381 0.000
I60 Subarachnoid haemorrhage
0.619 0.381 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.619 0.381 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.619 0.381 0.000
G92 Toxic encephalopathy
0.619 0.381 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.618 0.381 0.000
Q27 Other congenital malformations of peripheral vascular system
0.618 0.381 0.000
Chapter VIII Diseases of the ear and mastoid process
0.618 0.382 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.618 0.382 0.000
H16 Keratitis
0.617 0.383 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.617 0.383 0.000
H01 Other inflammation of eyelid
0.616 0.384 0.000
G81.1 Spastic hemiplegia
0.616 0.384 0.000
G81.0 Flaccid hemiplegia
0.616 0.384 0.000
H27 Other disorders of lens
0.616 0.384 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.616 0.384 0.000
I34 Nonrheumatic mitral valve disorders
0.616 0.384 0.000
G93.4 Encephalopathy, unspecified
0.615 0.384 0.000
E16.2 Hypoglycaemia, unspecified
0.615 0.385 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.614 0.386 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.612 0.388 0.000
O07 Failed attempted abortion
0.612 0.388 0.000
O06 Unspecified abortion
0.612 0.388 0.000
O05 Other abortion
0.612 0.388 0.000
O01 Hydatidiform mole
0.612 0.388 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.612 0.388 0.000
M06.3 Rheumatoid nodule
0.611 0.389 0.000
O72.1 Other immediate postpartum haemorrhage
0.611 0.389 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.611 0.389 0.000
O20.0 Threatened abortion
0.611 0.389 0.000
H43.3 Other vitreous opacities
0.610 0.390 0.000
I45.8 Other specified conduction disorders
0.609 0.391 0.000
M06.4 Inflammatory polyarthropathy
0.609 0.391 0.000
S80 Superficial injury of lower leg
0.608 0.391 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.608 0.392 0.000
T33-T35 Frostbite
0.607 0.393 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.607 0.393 0.000
T00-T07 Injuries involving multiple body regions
0.607 0.393 0.000
H18.7 Other corneal deformities
0.607 0.393 0.000
H18.6 Keratoconus
0.607 0.393 0.000
H18.3 Changes in corneal membranes
0.607 0.393 0.000
H18.2 Other corneal oedema
0.607 0.393 0.000
H18.1 Bullous keratopathy
0.607 0.393 0.000
H18.0 Corneal pigmentations and deposits
0.607 0.393 0.000
M05 Seropositive rheumatoid arthritis
0.606 0.394 0.000
M12 Other specific arthropathies
0.606 0.394 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.606 0.394 0.000
M08 Juvenile arthritis
0.606 0.394 0.000
I61 Intracerebral haemorrhage
0.606 0.394 0.000
O24 Diabetes mellitus in pregnancy
0.605 0.395 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.605 0.395 0.000
O69.8 Labour and delivery complicated by other cord complications
0.605 0.395 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.604 0.396 0.000
B35-B49 Mycoses
0.604 0.396 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.603 0.397 0.000
M87 Osteonecrosis
0.603 0.397 0.000
M25.0 Haemarthrosis
0.603 0.397 0.000
G61 Inflammatory polyneuropathy
0.602 0.397 0.000
A30-A49 Other bacterial diseases
0.602 0.398 0.000
I08.8 Other multiple valve diseases
0.602 0.398 0.000
H25.1 Senile nuclear cataract
0.602 0.398 0.000
Q63 Other congenital malformations of kidney
0.601 0.399 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.601 0.399 0.000
O72.3 Postpartum coagulation defects
0.600 0.400 0.000
I30.1 Infective pericarditis
0.599 0.401 0.000
E10 Insulin-dependent diabetes mellitus
0.599 0.401 0.000
S00.5 Superficial injury of lip and oral cavity
0.598 0.402 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.598 0.402 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.598 0.402 0.000
S20-S29 Injuries to the thorax
0.598 0.402 0.000
Q24 Other congenital malformations of heart
0.597 0.403 0.000
T66-T78 Other and unspecified effects of external causes
0.597 0.403 0.000
O70.2 Third degree perineal laceration during delivery
0.597 0.403 0.000
H18.5 Hereditary corneal dystrophies
0.597 0.403 0.000
I22.8 Subsequent myocardial infarction of other sites
0.597 0.403 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.596 0.404 0.000
M14.6 Neuropathic arthropathy
0.596 0.404 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.595 0.405 0.000
O82.1 Delivery by emergency Caesarean section
0.595 0.405 0.000
G70-G73 Diseases of myoneural junction and muscle
0.594 0.406 0.000
I45.9 Conduction disorder, unspecified
0.594 0.406 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.594 0.406 0.000
B50-B64 Protozoal diseases
0.594 0.406 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.594 0.406 0.000
A75-A79 Rickettsioses
0.594 0.406 0.000
A70-A74 Other diseases caused by chlamydiae
0.594 0.406 0.000
A20-A28 Certain zoonotic bacterial diseases
0.594 0.406 0.000
S00.3 Superficial injury of nose
0.592 0.408 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.591 0.409 0.000
M25.2 Flail joint
0.590 0.410 0.000
M25.1 Fistula of joint
0.590 0.410 0.000
O84 Multiple delivery
0.590 0.410 0.000
O83 Other assisted single delivery
0.590 0.410 0.000
I49.0 Ventricular fibrillation and flutter
0.590 0.410 0.000
G00 Bacterial meningitis, not elsewhere classified
0.590 0.410 0.000
H46 Optic neuritis
0.589 0.410 0.000
F30-F39 Mood [affective] disorders
0.590 0.410 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.588 0.412 0.000
O02 Other abnormal products of conception
0.588 0.412 0.000
S06 Intracranial injury
0.587 0.413 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.587 0.413 0.000
M06.8 Other specified rheumatoid arthritis
0.587 0.413 0.000
M06.2 Rheumatoid bursitis
0.587 0.413 0.000
M06.1 Adult-onset Still's disease
0.587 0.413 0.000
O61 Failed induction of labour
0.586 0.413 0.000
S50-S59 Injuries to the elbow and forearm
0.586 0.414 0.000
H43.2 Crystalline deposits in vitreous body
0.585 0.415 0.000
H43.0 Vitreous prolapse
0.585 0.415 0.000
I50.1 Left ventricular failure
0.585 0.415 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.585 0.415 0.000
G91 Hydrocephalus
0.584 0.416 0.000
M24.9 Joint derangement, unspecified
0.584 0.416 0.000
M24.7 Protrusio acetabuli
0.584 0.416 0.000
M24.5 Contracture of joint
0.584 0.416 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.584 0.416 0.000
S08 Traumatic amputation of part of head
0.584 0.416 0.000
S07 Crushing injury of head
0.584 0.416 0.000
S04 Injury of cranial nerves
0.584 0.416 0.000
M25.72 Osteophyte (Upper arm)
0.584 0.416 0.000
I37.1 Pulmonary valve insufficiency
0.584 0.416 0.000
O04.9 Complete or unspecified, without complication
0.584 0.416 0.000
M24.01 Loose body in joint (Shoulder region)
0.583 0.416 0.000
M23.4 Loose body in knee
0.583 0.417 0.000
I33.9 Acute endocarditis, unspecified
0.582 0.418 0.000
M89.3 Hypertrophy of bone
0.581 0.419 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.581 0.419 0.000
H20.0 Acute and subacute iridocyclitis
0.580 0.420 0.000
H20.8 Other iridocyclitis
0.580 0.420 0.000
S00.7 Multiple superficial injuries of head
0.580 0.420 0.000
S31 Open wound of abdomen, lower back and pelvis
0.579 0.420 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.579 0.421 0.000
H35.8 Other specified retinal disorders
0.579 0.421 0.000
O23.5 Infections of the genital tract in pregnancy
0.578 0.421 0.000
I45.0 Right fascicular block
0.577 0.423 0.000
O81.4 Vacuum extractor delivery
0.577 0.423 0.000
G64 Other disorders of peripheral nervous system
0.576 0.424 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.574 0.426 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.574 0.426 0.000
O69.3 Labour and delivery complicated by short cord
0.574 0.426 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.574 0.426 0.000
S30.2 Contusion of external genital organs
0.574 0.426 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.574 0.426 0.000
Q18 Other congenital malformations of face and neck
0.573 0.427 0.000
G40.9 Epilepsy, unspecified
0.573 0.427 0.000
B15-B19 Viral hepatitis
0.573 0.427 0.000
M21 Other acquired deformities of limbs
0.573 0.427 0.000
M88 Paget's disease of bone [osteitis deformans]
0.573 0.427 0.000
M22.8 Other disorders of patella
0.572 0.427 0.000
S01.7 Multiple open wounds of head
0.572 0.428 0.000
Q50-Q56 Congenital malformations of genital organs
0.571 0.428 0.000
B99-B99 Other infectious diseases
0.571 0.428 0.000
Q60.0 Renal agenesis, unilateral
0.571 0.429 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.570 0.430 0.000
T79-T79 Certain early complications of trauma
0.570 0.430 0.000
Chapter X Diseases of the respiratory system
0.570 0.430 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.570 0.430 0.000
O97 Death from sequelae of direct obstetric causes
0.570 0.430 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.570 0.430 0.000
O95 Obstetric death of unspecified cause
0.570 0.430 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.570 0.430 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.568 0.432 0.000
E06 Thyroiditis
0.568 0.432 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.568 0.432 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.568 0.432 0.000
I09.9 Rheumatic heart disease, unspecified
0.567 0.433 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.567 0.433 0.000
G93.3 Postviral fatigue syndrome
0.566 0.434 0.000
S05 Injury of eye and orbit
0.566 0.434 0.000
S81 Open wound of lower leg
0.566 0.434 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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