TreeWAS – Variant ID: rs79953717

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter II Neoplasms	0.999	0.001	0.000
Chapter XX External causes of morbidity and mortality	0.998	0.002	0.000
K55-K64 Other diseases of intestines	0.996	0.004	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.996	0.004	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.996	0.004	0.000
K63 Other diseases of intestine	0.995	0.005	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.991	0.009	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.988	0.012	0.000
M50-M54 Other dorsopathies	0.987	0.013	0.000
K63.5 Polyp of colon	0.979	0.021	0.000
C15-C26 Malignant neoplasms of digestive organs	0.977	0.023	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.970	0.030	0.000
C64-C68 Malignant neoplasms of urinary tract	0.970	0.030	0.000
C18 Malignant neoplasm of colon	0.966	0.034	0.000
M54 Dorsalgia	0.966	0.034	0.000
Y43 Primarily systemic agents	0.964	0.036	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.963	0.037	0.000
Chapter VI Diseases of the nervous system	0.956	0.044	0.000
M54.5 Low back pain	0.954	0.046	0.000
Chapter VII Diseases of the eye and adnexa	0.954	0.046	0.000
M15-M19 Arthrosis	0.952	0.048	0.000
M16 Coxarthrosis [arthrosis of hip]	0.948	0.052	0.000
D50-D53 Nutritional anaemias	0.948	0.052	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.946	0.054	0.000
M16.9 Coxarthrosis, unspecified	0.944	0.056	0.000
Chapter X Diseases of the respiratory system	0.943	0.057	0.000
L40-L45 Papulosquamous disorders	0.943	0.057	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.942	0.058	0.000
L40 Psoriasis	0.940	0.060	0.000
K50-K52 Noninfective enteritis and colitis	0.937	0.063	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.935	0.065	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.932	0.068	0.000
G40-G47 Episodic and paroxysmal disorders	0.931	0.069	0.000
M54.59 Low back pain (Site unspecified)	0.930	0.070	0.000
L40.5 Arthropathic psoriasis	0.927	0.073	0.000
J09-J18 Influenza and pneumonia	0.926	0.074	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.914	0.086	0.000
D50 Iron deficiency anaemia	0.914	0.086	0.000
K08 Other disorders of teeth and supporting structures	0.912	0.088	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.910	0.090	0.000
M70-M79 Other soft tissue disorders	0.907	0.093	0.000
K04 Diseases of pulp and periapical tissues	0.906	0.094	0.000
K51 Ulcerative colitis	0.901	0.099	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.895	0.105	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.894	0.106	0.000
G43 Migraine	0.893	0.107	0.000
Y43.3 Other antineoplastic drugs	0.892	0.108	0.000
M45-M49 Spondylopathies	0.890	0.110	0.000
K59 Other functional intestinal disorders	0.889	0.111	0.000
L40.9 Psoriasis, unspecified	0.888	0.112	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.888	0.112	0.000
D50.9 Iron deficiency anaemia, unspecified	0.888	0.112	0.000
H25-H28 Disorders of lens	0.887	0.113	0.000
D68 Other coagulation defects	0.886	0.114	0.000
D10-D36 Benign neoplasms	0.885	0.115	0.000
C18.7 Sigmoid colon	0.884	0.116	0.000
K63.3 Ulcer of intestine	0.884	0.116	0.000
K04.5 Chronic apical periodontitis	0.880	0.120	0.000
S60-S69 Injuries to the wrist and hand	0.879	0.121	0.000
G43.9 Migraine, unspecified	0.874	0.126	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.869	0.131	0.000
C67 Malignant neoplasm of bladder	0.868	0.132	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.867	0.133	0.000
D80-D89 Certain disorders involving the immune mechanism	0.860	0.140	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.858	0.142	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.858	0.142	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.857	0.143	0.000
K63.1 Perforation of intestine (nontraumatic)	0.854	0.146	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.854	0.146	0.000
J18 Pneumonia, organism unspecified	0.853	0.147	0.000
M54.57 Low back pain (Lumbosacral region)	0.853	0.147	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.851	0.149	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.847	0.153	0.000
D12.5 Sigmoid colon	0.847	0.153	0.000
K00 Disorders of tooth development and eruption	0.846	0.154	0.000
K63.8 Other specified diseases of intestine	0.845	0.155	0.000
M54.2 Cervicalgia	0.843	0.156	0.000
K01 Embedded and impacted teeth	0.841	0.159	0.000
C18.6 Descending colon	0.838	0.162	0.000
C81 Hodgkin's disease	0.837	0.163	0.000
M40-M43 Deforming dorsopathies	0.836	0.164	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.834	0.166	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.834	0.166	0.000
J60-J70 Lung diseases due to external agents	0.833	0.167	0.000
M45 Ankylosing spondylitis	0.832	0.168	0.000
D12.3 Transverse colon	0.831	0.169	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.831	0.169	0.000
C20 Malignant neoplasm of rectum	0.831	0.169	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.831	0.169	0.000
H53-H54 Visual disturbances and blindness	0.830	0.170	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.828	0.172	0.000
K51.9 Ulcerative colitis, unspecified	0.826	0.174	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.824	0.176	0.000
H55-H59 Other disorders of eye and adnexa	0.822	0.178	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.822	0.178	0.000
D00-D09 In situ neoplasms	0.822	0.178	0.000
K07 Dentofacial anomalies [including malocclusion]	0.821	0.179	0.000
K70-K77 Diseases of liver	0.821	0.179	0.000
M05-M14 Inflammatory polyarthropathies	0.820	0.180	0.000
K62 Other diseases of anus and rectum	0.820	0.180	0.000
Y45.0 Opioids and related analgesics	0.819	0.181	0.000
H30-H36 Disorders of choroid and retina	0.818	0.182	0.000
C18.5 Splenic flexure	0.815	0.185	0.000
K65-K67 Diseases of peritoneum	0.811	0.189	0.000
Y95 Nosocomial condition	0.811	0.189	0.000
M50 Cervical disk disorders	0.811	0.189	0.000
K55 Vascular disorders of intestine	0.810	0.190	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.809	0.191	0.000
C18.3 Hepatic flexure	0.808	0.192	0.000
S50-S59 Injuries to the elbow and forearm	0.808	0.192	0.000
D12.6 Colon, unspecified	0.807	0.193	0.000
G44 Other headache syndromes	0.806	0.194	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.806	0.194	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.805	0.195	0.000
M79.8 Other specified soft tissue disorders	0.802	0.198	0.000
H26 Other cataract	0.801	0.199	0.000
M60-M63 Disorders of muscles	0.799	0.201	0.000
T82.1 Mechanical complication of cardiac electronic device	0.798	0.202	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.797	0.203	0.000
J18.1 Lobar pneumonia, unspecified	0.795	0.205	0.000
Y43.1 Antineoplastic antimetabolites	0.793	0.207	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.793	0.207	0.000
D12.0 Caecum	0.793	0.207	0.000
Y40 Systemic antibiotics	0.792	0.208	0.000
S10-S19 Injuries to the neck	0.792	0.208	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.792	0.208	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.791	0.209	0.000
C18.2 Ascending colon	0.790	0.210	0.000
D68.0 Von Willebrand's disease	0.789	0.211	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.789	0.211	0.000
H33 Retinal detachments and breaks	0.788	0.212	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.787	0.213	0.000
J95-J99 Other diseases of the respiratory system	0.787	0.213	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.786	0.214	0.000
D45 Polycythaemia vera	0.786	0.214	0.000
C23 Malignant neoplasm of gallbladder	0.786	0.214	0.000
K09 Cysts of oral region, not elsewhere classified	0.784	0.216	0.000
M16.1 Other primary coxarthrosis	0.784	0.216	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.784	0.216	0.000
D55-D59 Haemolytic anaemias	0.783	0.217	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.781	0.219	0.000
K10 Other diseases of jaws	0.780	0.220	0.000
M65-M68 Disorders of synovium and tendon	0.779	0.221	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.778	0.222	0.000
C73 Malignant neoplasm of thyroid gland	0.776	0.224	0.000
H33.0 Retinal detachment with retinal break	0.775	0.225	0.000
K63.4 Enteroptosis	0.774	0.226	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.773	0.227	0.000
Y43.4 Immunosuppressive agents	0.773	0.227	0.000
M07 Psoriatic and enteropathic arthropathies	0.772	0.227	0.000
M54.1 Radiculopathy	0.771	0.229	0.000
K08.3 Retained dental root	0.771	0.229	0.000
X10-X19 Contact with heat and hot substances	0.770	0.230	0.000
K59.9 Functional intestinal disorder, unspecified	0.769	0.231	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.768	0.232	0.000
M51 Other intervertebral disk disorders	0.768	0.232	0.000
C18.9 Colon, unspecified	0.768	0.232	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.767	0.233	0.000
K12 Stomatitis and related lesions	0.766	0.234	0.000
K62.1 Rectal polyp	0.765	0.235	0.000
Y45.2 Propionic acid derivatives	0.763	0.237	0.000
Y43.0 Antiallergic and antiemetic drugs	0.762	0.238	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.762	0.238	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.761	0.239	0.000
C67.9 Bladder, unspecified	0.761	0.239	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.759	0.241	0.000
L42 Pityriasis rosea	0.759	0.241	0.000
M53 Other dorsopathies, not elsewhere classified	0.757	0.243	0.000
D68.6 Other Thrombophilia	0.756	0.244	0.000
Y45.1 Salicylates	0.755	0.245	0.000
C17 Malignant neoplasm of small intestine	0.755	0.245	0.000
K11 Diseases of salivary glands	0.754	0.246	0.000
H26.8 Other specified cataract	0.754	0.246	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.753	0.247	0.000
H53 Visual disturbances	0.752	0.248	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.752	0.248	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.751	0.249	0.000
J00-J06 Acute upper respiratory infections	0.751	0.249	0.000
D66 Hereditary factor VIII deficiency	0.750	0.250	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.749	0.251	0.000
Y52 Agents primarily affecting the cardiovascular system	0.749	0.251	0.000
T86 Failure and rejection of transplanted organs and tissues	0.748	0.252	0.000
C65 Malignant neoplasm of renal pelvis	0.747	0.252	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.746	0.254	0.000
V40-V49 Car occupant injured in transport accident	0.745	0.255	0.000
D12.4 Descending colon	0.744	0.256	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.743	0.257	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.743	0.257	0.000
J14 Pneumonia due to Haemophilus influenzae	0.741	0.259	0.000
K63.9 Disease of intestine, unspecified	0.740	0.260	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.739	0.261	0.000
M07.3 Other psoriatic arthropathies	0.739	0.261	0.000
M54.22 Cervicalgia (Cervical region)	0.739	0.261	0.000
K59.8 Other specified functional intestinal disorders	0.737	0.263	0.000
C81.9 Hodgkin's disease, unspecified	0.737	0.263	0.000
X60-X84 Intentional self-harm	0.736	0.264	0.000
G70-G73 Diseases of myoneural junction and muscle	0.736	0.264	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.735	0.265	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.735	0.265	0.000
G40 Epilepsy	0.735	0.265	0.000
T92 Sequelae of injuries of upper limb	0.734	0.266	0.000
H27 Other disorders of lens	0.733	0.267	0.000
T82.3 Mechanical complication of other vascular grafts	0.733	0.267	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.732	0.268	0.000
W00-W19 Falls	0.731	0.269	0.000
M77 Other enthesopathies	0.730	0.270	0.000
K51.2 Ulcerative (chronic) proctitis	0.729	0.271	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.729	0.271	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.728	0.272	0.000
M54.55 Low back pain (Thoracolumbar region)	0.728	0.272	0.000
S64 Injury of nerves at wrist and hand level	0.728	0.272	0.000
D68.8 Other specified coagulation defects	0.728	0.272	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.727	0.273	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.726	0.274	0.000
S67 Crushing injury of wrist and hand	0.726	0.274	0.000
K63.2 Fistula of intestine	0.726	0.274	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.725	0.275	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.725	0.275	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.724	0.276	0.000
M91-M94 Chondropathies	0.724	0.276	0.000
Chapter XXII Codes for special purposes	0.724	0.276	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.724	0.276	0.000
J17 Pneumonia in diseases classified elsewhere	0.723	0.277	0.000
D36 Benign neoplasm of other and unspecified sites	0.723	0.277	0.000
D41.4 Bladder	0.722	0.278	0.000
K07.3 Anomalies of tooth position	0.722	0.278	0.000
L43 Lichen planus	0.720	0.280	0.000
K01.1 Impacted teeth	0.719	0.281	0.000
K62.0 Anal polyp	0.718	0.282	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.718	0.282	0.000
D86 Sarcoidosis	0.718	0.282	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M54.50 Low back pain (Multiple sites in spine)	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284	0.000
X20-X29 Contact with venomous animals and plants	0.716	0.284	0.000
Y35-Y36 Legal intervention and operations of war	0.715	0.285	0.000
Y10-Y34 Event of undetermined intent	0.715	0.285	0.000
Y00-Y09 Assault	0.715	0.285	0.000
X85-X99 Assault	0.715	0.285	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.715	0.285	0.000
X50-X57 Overexertion, travel and privation	0.715	0.285	0.000
X30-X39 Exposure to forces of nature	0.715	0.285	0.000
X00-X09 Exposure to smoke, fire and flames	0.715	0.285	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285	0.000
W75-W84 Other accidental threats to breathing	0.715	0.285	0.000
W65-W74 Accidental drowning and submersion	0.715	0.285	0.000
W50-W64 Exposure to animate mechanical forces	0.715	0.285	0.000
V98-V99 Other and unspecified transport accidents	0.715	0.285	0.000
V95-V97 Air and space transport accidents	0.715	0.285	0.000
V90-V94 Water transport accidents	0.715	0.285	0.000
V80-V89 Other land transport accidents	0.715	0.285	0.000
V70-V79 Bus occupant injured in transport accident	0.715	0.285	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285	0.000
V01-V09 Pedestrian injured in transport accident	0.715	0.285	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.715	0.285	0.000
D75 Other diseases of blood and blood-forming organs	0.715	0.285	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.714	0.286	0.000
K51.4 Pseudopolyposis of colon	0.714	0.286	0.000
Y59 Other and unspecified vaccines and biological substances	0.714	0.286	0.000
Y58 Bacterial vaccines	0.714	0.286	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.714	0.286	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.714	0.286	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.714	0.286	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.714	0.286	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.714	0.286	0.000
Y48 Anaesthetics and therapeutic gases	0.714	0.286	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.714	0.286	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.714	0.286	0.000
M75 Shoulder lesions	0.714	0.286	0.000
K63.0 Abscess of intestine	0.713	0.287	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.713	0.287	0.000
D52 Folate deficiency anaemia	0.713	0.287	0.000
T33-T35 Frostbite	0.713	0.287	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287	0.000
T00-T07 Injuries involving multiple body regions	0.713	0.287	0.000
S60 Superficial injury of wrist and hand	0.713	0.287	0.000
Chapter XXI Factors influencing health status and contact with health services	0.712	0.288	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.710	0.290	0.000
K03 Other diseases of hard tissues of teeth	0.710	0.290	0.000
K61 Abscess of anal and rectal regions	0.709	0.291	0.000
C66 Malignant neoplasm of ureter	0.709	0.291	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.709	0.291	0.000
T87 Complications peculiar to reattachment and amputation	0.708	0.291	0.000
M43 Other deforming dorsopathies	0.708	0.292	0.000
H18 Other disorders of cornea	0.707	0.293	0.000
M16.3 Other dysplastic coxarthrosis	0.707	0.293	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.706	0.294	0.000
S70-S79 Injuries to the hip and thigh	0.705	0.295	0.000
M47 Spondylosis	0.705	0.295	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.704	0.296	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.704	0.296	0.000
D16 Benign neoplasm of bone and articular cartilage	0.703	0.296	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.703	0.297	0.000
K50 Crohn's disease [regional enteritis]	0.703	0.297	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.703	0.297	0.000
S69 Other and unspecified injuries of wrist and hand	0.702	0.298	0.000
J18.0 Bronchopneumonia, unspecified	0.702	0.298	0.000
H10-H13 Disorders of conjunctiva	0.701	0.299	0.000
G44.2 Tension-type headache	0.701	0.299	0.000
C21 Malignant neoplasm of anus and anal canal	0.701	0.299	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.700	0.300	0.000
D72 Other disorders of white blood cells	0.700	0.300	0.000
T79-T79 Certain early complications of trauma	0.700	0.300	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.699	0.301	0.000
M50.3 Other cervical disk degeneration	0.699	0.301	0.000
C67.1 Dome of bladder	0.699	0.301	0.000
K90-K93 Other diseases of the digestive system	0.698	0.302	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.697	0.303	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.697	0.303	0.000
Chapter VIII Diseases of the ear and mastoid process	0.696	0.304	0.000
H20 Iridocyclitis	0.696	0.304	0.000
K59.0 Constipation	0.696	0.304	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.696	0.304	0.000
Y45.8 Other analgesics and antipyretics	0.696	0.304	0.000
Y45.5 4-Aminophenol derivatives	0.696	0.304	0.000
Y45.4 Antirheumatics	0.696	0.304	0.000
D80 Immunodeficiency with predominantly antibody defects	0.695	0.304	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.695	0.305	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.695	0.305	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.695	0.305	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.694	0.306	0.000
K74 Fibrosis and cirrhosis of liver	0.694	0.306	0.000
K00.9 Disorder of tooth development, unspecified	0.694	0.306	0.000
C67.2 Lateral wall of bladder	0.693	0.307	0.000
C18.8 Overlapping lesion of colon	0.693	0.307	0.000
C18.1 Appendix	0.693	0.307	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.693	0.307	0.000
M54.8 Other dorsalgia	0.692	0.307	0.000
M54.0 Panniculitis affecting regions of neck and back	0.692	0.307	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.692	0.308	0.000
Y43.9 Primarily systemic agent, unspecified	0.691	0.309	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.691	0.309	0.000
Y43.6 Enzymes, not elsewhere classified	0.691	0.309	0.000
Y43.5 Acidifying and alkalising agents	0.691	0.309	0.000
Y43.2 Antineoplastic natural products	0.691	0.309	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.690	0.310	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.690	0.310	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.690	0.310	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.690	0.310	0.000
V20-V29 Motorcycle rider injured in transport accident	0.690	0.310	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.689	0.311	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.689	0.311	0.000
J02 Acute pharyngitis	0.686	0.314	0.000
D12.2 Ascending colon	0.686	0.314	0.000
J84 Other interstitial pulmonary diseases	0.686	0.314	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.685	0.314	0.000
K65 Peritonitis	0.685	0.315	0.000
Y44 Agents primarily affecting blood constituents	0.684	0.316	0.000
M54.54 Low back pain-Thoracic	0.684	0.316	0.000
M54.53 Low back pain-Cervicothoracic	0.684	0.316	0.000
M54.52 Low back pain-Cervical	0.684	0.316	0.000
M54.51 Low back pain-Occipit-atl-axl	0.684	0.316	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.684	0.316	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.684	0.316	0.000
K00.6 Disturbances in tooth eruption	0.683	0.317	0.000
M15 Polyarthrosis	0.683	0.317	0.000
G47 Sleep disorders	0.683	0.317	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.682	0.318	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.681	0.319	0.000
C88 Malignant immunoproliferative diseases	0.681	0.319	0.000
K09.0 Developmental odontogenic cysts	0.681	0.319	0.000
M16.7 Other secondary coxarthrosis	0.680	0.320	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.680	0.320	0.000
M16.5 Other posttraumatic coxarthrosis	0.680	0.320	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.680	0.320	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.680	0.320	0.000
J98 Other respiratory disorders	0.680	0.320	0.000
M86-M90 Other osteopathies	0.680	0.320	0.000
D53 Other nutritional anaemias	0.679	0.320	0.000
K51.5 Mucosal proctocolitis	0.679	0.321	0.000
D09 Carcinoma in situ of other and unspecified sites	0.679	0.321	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.678	0.322	0.000
L10-L14 Bullous disorders	0.678	0.322	0.000
T21 Burn and corrosion of trunk	0.676	0.324	0.000
L44 Other papulosquamous disorders	0.676	0.324	0.000
L41 Parapsoriasis	0.676	0.324	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.676	0.324	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.675	0.325	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.675	0.325	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.675	0.325	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.675	0.325	0.000
K55.9 Vascular disorder of intestine, unspecified	0.675	0.325	0.000
M54.6 Pain in thoracic spine	0.675	0.325	0.000
C92 Myeloid leukaemia	0.675	0.325	0.000
L20-L30 Dermatitis and eczema	0.674	0.326	0.000
C81.1 Nodular sclerosis	0.674	0.326	0.000
L40.8 Other psoriasis	0.674	0.326	0.000
L40.4 Guttate psoriasis	0.674	0.326	0.000
L40.3 Pustulosis palmaris et plantaris	0.674	0.326	0.000
L40.2 Acrodermatitis continua	0.674	0.326	0.000
L40.1 Generalised pustular psoriasis	0.674	0.326	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.673	0.327	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.672	0.328	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.672	0.328	0.000
K59.3 Megacolon, not elsewhere classified	0.672	0.328	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.670	0.329	0.000
D67 Hereditary factor IX deficiency	0.670	0.330	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.670	0.330	0.000
K57 Diverticular disease of intestine	0.061	0.331	0.608
X40-X49 Accidental poisoning by and exposure to noxious substances	0.668	0.331	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.668	0.332	0.000
C95 Leukaemia of unspecified cell type	0.668	0.332	0.000
C94 Other leukaemias of specified cell type	0.668	0.332	0.000
C93 Monocytic leukaemia	0.668	0.332	0.000
C86 Other specified types of T/NK-cell lymphoma	0.668	0.332	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.668	0.332	0.000
M79.2 Neuralgia and neuritis, unspecified	0.668	0.332	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.668	0.332	0.000
G41 Status epilepticus	0.668	0.332	0.000
K51.8 Other ulcerative colitis	0.668	0.332	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.667	0.333	0.000
K70 Alcoholic liver disease	0.667	0.333	0.000
G80 Infantile cerebral palsy	0.666	0.333	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.666	0.334	0.000
E20-E35 Disorders of other endocrine glands	0.666	0.334	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.665	0.334	0.000
D46 Myelodysplastic syndromes	0.665	0.335	0.000
K86 Other diseases of pancreas	0.665	0.335	0.000
K02 Dental caries	0.664	0.336	0.000
M75.1 Rotator cuff syndrome	0.664	0.336	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.664	0.336	0.000
J12 Viral pneumonia, not elsewhere classified	0.664	0.336	0.000
J11 Influenza, virus not identified	0.664	0.336	0.000
J09 Influenza due to certain identified influenza virus	0.664	0.336	0.000
J69 Pneumonitis due to solids and liquids	0.662	0.338	0.000
D05 Carcinoma in situ of breast	0.662	0.338	0.000
D32 Benign neoplasm of meninges	0.661	0.339	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.659	0.341	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.659	0.341	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.658	0.342	0.000
M62 Other disorders of muscle	0.656	0.344	0.000
S68 Traumatic amputation of wrist and hand	0.656	0.344	0.000
M51.8 Other specified intervertebral disk disorders	0.656	0.344	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.656	0.344	0.000
H25 Senile cataract	0.655	0.345	0.000
D50.1 Sideropenic dysphagia	0.655	0.345	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.655	0.345	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.655	0.345	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.654	0.346	0.000
J15.1 Pneumonia due to Pseudomonas	0.654	0.346	0.000
Y40.9 Systemic antibiotic, unspecified	0.654	0.346	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.653	0.347	0.000
S36 Injury of intra-abdominal organs	0.653	0.347	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.652	0.348	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.652	0.348	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.652	0.348	0.000
S54 Injury of nerves at forearm level	0.652	0.348	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.651	0.348	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.651	0.349	0.000
H57 Other disorders of eye and adnexa	0.651	0.349	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.651	0.349	0.000
H53.1 Subjective visual disturbances	0.651	0.349	0.000
C18.4 Transverse colon	0.650	0.349	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.650	0.349	0.000
K62.9 Disease of anus and rectum, unspecified	0.650	0.349	0.000
L50-L54 Urticaria and erythema	0.650	0.350	0.000
H53.2 Diplopia	0.650	0.350	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.649	0.350	0.000
K04.3 Abnormal hard tissue formation in pulp	0.649	0.350	0.000
K04.2 Pulp degeneration	0.649	0.350	0.000
K04.1 Necrosis of pulp	0.649	0.350	0.000
K04.0 Pulpitis	0.649	0.350	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.649	0.351	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.649	0.351	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.649	0.351	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.648	0.351	0.000
K55.1 Chronic vascular disorders of intestine	0.648	0.352	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.648	0.352	0.000
M76 Enthesopathies of lower limb, excluding foot	0.646	0.353	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.646	0.354	0.000
C18.0 Caecum	0.646	0.354	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.645	0.355	0.000
M54.29 Cervicalgia-Site unspe	0.644	0.356	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.644	0.356	0.000
T90 Sequelae of injuries of head	0.643	0.356	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.643	0.357	0.000
J80 Adult respiratory distress syndrome	0.642	0.358	0.000
S40-S49 Injuries to the shoulder and upper arm	0.642	0.358	0.000
K40-K46 Hernia	0.642	0.358	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.641	0.359	0.000
Y98 Lifestyle-related condition	0.641	0.359	0.000
Y97 Environmental-pollution-related condition	0.641	0.359	0.000
Y96 Work-related condition	0.641	0.359	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.641	0.359	0.000
Y42.7 Androgens and anabolic congeners	0.640	0.360	0.000
G43.8 Other migraine	0.640	0.360	0.000
G43.3 Complicated migraine	0.640	0.360	0.000
G43.2 Status migrainosus	0.640	0.360	0.000
G43.0 Migraine without aura [common migraine]	0.640	0.360	0.000
J02.9 Acute pharyngitis, unspecified	0.640	0.360	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.640	0.360	0.000
K76 Other diseases of liver	0.640	0.360	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.639	0.361	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations