TreeWAS – Variant ID: rs8042680

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.886	0.114	0.000
E11 Non-insulin-dependent diabetes mellitus	0.886	0.114	0.000
E14.9 Without complications	0.872	0.128	0.000
E10-E14 Diabetes mellitus	0.871	0.129	0.000
E14 Unspecified diabetes mellitus	0.869	0.131	0.000
E11.4 With neurological complications	0.826	0.174	0.000
E11.2 With renal complications	0.790	0.210	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.238	0.762
C79 Secondary malignant neoplasm of other sites	0.000	0.249	0.751
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.259	0.741
E11.3 With ophthalmic complications	0.715	0.285	0.000
E11.5 With peripheral circulatory complications	0.706	0.294	0.000
E10 Insulin-dependent diabetes mellitus	0.688	0.312	0.000
E14.5 With peripheral circulatory complications	0.683	0.317	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.325	0.675
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.328	0.672
E14.6 With other specified complications	0.670	0.330	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.336	0.664
E11.0 With coma	0.653	0.347	0.000
E14.2 Withrenal complications	0.646	0.354	0.000
E11.7 With multiple complications	0.635	0.365	0.000
E12 Malnutrition-related diabetes mellitus	0.624	0.375	0.000
E14.7 With multiple complications	0.623	0.377	0.000
E14.0 With coma	0.623	0.377	0.000
E11.8 With unspecified complications	0.617	0.383	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.384	0.616
E14.4 With neurological complications	0.611	0.389	0.000
E10.3 With ophthalmic complications	0.596	0.404	0.000
E11.6 With other specified complications	0.594	0.406	0.000
E10.5 With peripheral circulatory complications	0.582	0.418	0.000
E14.8 With unspecified complications	0.569	0.430	0.000
E13 Other specified diabetes mellitus	0.567	0.433	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.439	0.561
E10.0 With coma	0.539	0.461	0.000
E10.7 With multiple complications	0.531	0.469	0.000
E10.9 Without complications	0.529	0.471	0.000
E10.6 With other specified complications	0.518	0.481	0.000
E10.2 With renal complications	0.505	0.495	0.000
E14.3 With ophthalmic complications	0.486	0.514	0.000
E14.1 With ketoacidosis	0.483	0.517	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.543	0.457
E12.9 Without complications	0.448	0.552	0.000
E12.8 With unspecified complications	0.448	0.552	0.000
E12.7 With multiple complications	0.448	0.552	0.000
E12.6 With other specified complications	0.448	0.552	0.000
E12.5 With peripheral circulatory complications	0.448	0.552	0.000
E12.4 With neurological complications	0.448	0.552	0.000
E12.3 With ophthalmic complications	0.448	0.552	0.000
E12.2 With renal complications	0.448	0.552	0.000
E12.1 With ketoacidosis	0.448	0.552	0.000
E12.0 With coma	0.448	0.552	0.000
E13.8 With unspecified complications	0.406	0.593	0.000
E13.7 With multiple complications	0.406	0.593	0.000
E13.6 With other specified complications	0.406	0.593	0.000
E13.5 With peripheral circulatory complications	0.406	0.593	0.000
E13.4 With neurological complications	0.406	0.593	0.000
E13.3 With ophthalmic complications	0.406	0.593	0.000
E13.2 With renal complications	0.406	0.593	0.000
E13.1 With ketoacidosis	0.406	0.593	0.000
E13.0 With coma	0.406	0.593	0.000
E10.8 With unspecified complications	0.381	0.619	0.000
E13.9 Without complications	0.349	0.651	0.000
E11.1 With ketoacidosis	0.337	0.663	0.001
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.663	0.336
E10.1 With ketoacidosis	0.313	0.687	0.000
E10.4 With neurological complications	0.281	0.718	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.001	0.738	0.261
K90.9 Intestinal malabsorption, unspecified	0.031	0.969	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.027	0.973	0.000
E20-E35 Disorders of other endocrine glands	0.024	0.976	0.000
E34 Other endocrine disorders	0.024	0.976	0.000
I84.4 External haemorrhoids with other complications	0.022	0.978	0.000
E34.9 Endocrine disorder, unspecified	0.022	0.978	0.000
E34.0 Carcinoid syndrome	0.021	0.979	0.000
E20 Hypoparathyroidism	0.021	0.979	0.000
E23 Hypofunction and other disorders of pituitary gland	0.020	0.980	0.000
E31 Polyglandular dysfunction	0.020	0.980	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.019	0.981	0.000
E24 Cushing's syndrome	0.018	0.982	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.982	0.018
E34.8 Other specified endocrine disorders	0.018	0.982	0.000
E20.9 Hypoparathyroidism, unspecified	0.018	0.982	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.018	0.982	0.000
E32 Diseases of thymus	0.018	0.982	0.000
E30 Disorders of puberty, not elsewhere classified	0.018	0.982	0.000
E34.5 Androgen resistance syndrome	0.017	0.983	0.000
E34.4 Constitutional tall stature	0.017	0.983	0.000
E34.3 Short stature, not elsewhere classified	0.017	0.983	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.017	0.983	0.000
E34.1 Other hypersecretion of intestinal hormones	0.017	0.983	0.000
E23.2 Diabetes insipidus	0.017	0.983	0.000
E65-E68 Obesity and other hyperalimentation	0.017	0.983	0.000
E29 Testicular dysfunction	0.017	0.983	0.000
E26 Hyperaldosteronism	0.017	0.983	0.000
E40-E46 Malnutrition	0.017	0.983	0.000
E27 Other disorders of adrenal gland	0.017	0.983	0.000
E25 Adrenogenital disorders	0.016	0.984	0.000
E31.0 Autoimmune polyglandular failure	0.016	0.984	0.000
E23.6 Other disorders of pituitary gland	0.016	0.984	0.000
E24.0 Pituitary-dependent Cushing's disease	0.015	0.985	0.000
E20.8 Other hypoparathyroidism	0.015	0.985	0.000
E20.1 Pseudohypoparathyroidism	0.015	0.985	0.000
E20.0 Idiopathic hypoparathyroidism	0.015	0.985	0.000
E28 Ovarian dysfunction	0.015	0.985	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.985	0.015
E23.7 Disorder of pituitary gland, unspecified	0.014	0.986	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.014	0.986	0.000
E23.1 Drug-induced hypopituitarism	0.014	0.986	0.000
E31.9 Polyglandular dysfunction, unspecified	0.014	0.986	0.000
E31.8 Other polyglandular dysfunction	0.014	0.986	0.000
E31.1 Polyglandular hyperfunction	0.014	0.986	0.000
E66 Obesity	0.014	0.986	0.000
E15 Nondiabetic hypoglycaemic coma	0.014	0.986	0.000
E24.2 Drug-induced Cushing's syndrome	0.014	0.986	0.000
E24.8 Other Cushing's syndrome	0.013	0.986	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.013	0.986	0.000
E24.3 Ectopic ACTH syndrome	0.013	0.986	0.000
E24.1 Nelson's syndrome	0.013	0.986	0.000
E27.2 Addisonian crisis	0.013	0.987	0.000
E26.9 Hyperaldosteronism, unspecified	0.013	0.987	0.000
E16 Other disorders of pancreatic internal secretion	0.013	0.987	0.000
E30.9 Disorder of puberty, unspecified	0.013	0.987	0.000
E30.8 Other disorders of puberty	0.013	0.987	0.000
E30.1 Precocious puberty	0.013	0.987	0.000
E30.0 Delayed puberty	0.013	0.987	0.000
E32.9 Disease of thymus, unspecified	0.013	0.987	0.000
E32.8 Other diseases of thymus	0.013	0.987	0.000
E32.1 Abscess of thymus	0.013	0.987	0.000
E32.0 Persistent hyperplasia of thymus	0.013	0.987	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.013	0.987	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.013	0.987	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.013	0.987	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.013	0.987	0.000
E22 Hyperfunction of pituitary gland	0.013	0.987	0.000
I60 Subarachnoid haemorrhage	0.000	0.987	0.013
E67 Other hyperalimentation	0.012	0.987	0.000
E68 Sequelae of hyperalimentation	0.012	0.987	0.000
E29.9 Testicular dysfunction, unspecified	0.012	0.987	0.000
E29.8 Other testicular dysfunction	0.012	0.987	0.000
E29.0 Testicular hyperfunction	0.012	0.987	0.000
E26.8 Other hyperaldosteronism	0.012	0.987	0.000
E26.1 Secondary hyperaldosteronism	0.012	0.987	0.000
E27.9 Disorder of adrenal gland, unspecified	0.012	0.988	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.012	0.988	0.000
E45 Retarded development following protein-energy malnutrition	0.012	0.988	0.000
E43 Unspecified severe protein-energy malnutrition	0.012	0.988	0.000
E42 Marasmic kwashiorkor	0.012	0.988	0.000
E41 Nutritional marasmus	0.012	0.988	0.000
E40 Kwashiorkor	0.012	0.988	0.000
E27.5 Adrenomedullary hyperfunction	0.012	0.988	0.000
E27.0 Other adrenocortical overactivity	0.012	0.988	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.988	0.012
E29.1 Testicular hypofunction	0.012	0.988	0.000
E25.9 Adrenogenital disorder, unspecified	0.012	0.988	0.000
E25.8 Other adrenogenital disorders	0.012	0.988	0.000
E27.8 Other specified disorders of adrenal gland	0.012	0.988	0.000
E66.8 Other obesity	0.012	0.988	0.000
E24.9 Cushing's syndrome, unspecified	0.012	0.988	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.012	0.988	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.989	0.011
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.989	0.011
E66.9 Obesity, unspecified	0.011	0.989	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.011	0.989	0.000
E26.0 Primary hyperaldosteronism	0.011	0.989	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.011	0.989	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.989	0.011
E28.9 Ovarian dysfunction, unspecified	0.011	0.989	0.000
E28.8 Other ovarian dysfunction	0.011	0.989	0.000
E28.1 Androgen excess	0.011	0.989	0.000
E28.0 Oestrogen excess	0.011	0.989	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.010	0.989	0.000
E28.3 Primary ovarian failure	0.011	0.989	0.000
E66.1 Drug-induced obesity	0.010	0.989	0.000
E16.1 Other hypoglycaemia	0.010	0.990	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.990	0.010
E16.0 Drug-induced hypoglycaemia without coma	0.010	0.990	0.000
E23.0 Hypopituitarism	0.010	0.990	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.010	0.990	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.010	0.990	0.000
E16.4 Abnormal secretion of gastrin	0.010	0.990	0.000
E16.3 Increased secretion of glucagon	0.010	0.990	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.990	0.010
E27.1 Primary adrenocortical insufficiency	0.009	0.990	0.000
E46 Unspecified protein-energy malnutrition	0.009	0.991	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.009	0.991	0.000
E22.8 Other hyperfunction of pituitary gland	0.009	0.991	0.000
E21.2 Other hyperparathyroidism	0.009	0.991	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.991	0.009
E67.8 Other specified hyperalimentation	0.009	0.991	0.000
E67.3 Hypervitaminosis D	0.009	0.991	0.000
E67.2 Megavitamin-B6 syndrome	0.009	0.991	0.000
E67.1 Hypercarotenaemia	0.009	0.991	0.000
E67.0 Hypervitaminosis A	0.009	0.991	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.991	0.009
E44.1 Mild protein-energy malnutrition	0.009	0.991	0.000
E44.0 Moderate protein-energy malnutrition	0.009	0.991	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.991	0.009
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.991	0.009
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.991	0.009
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.009	0.991	0.000
E66.0 Obesity due to excess calories	0.009	0.991	0.000
E28.2 Polycystic ovarian syndrome	0.009	0.991	0.000
E21.4 Other specified disorders of parathyroid gland	0.009	0.991	0.000
C76.0 Head, face and neck	0.000	0.991	0.008
C80 Malignant neoplasm without specification of site	0.000	0.991	0.009
C76.3 Pelvis	0.000	0.991	0.008
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.991	0.008
C76.7 Other ill-defined sites	0.000	0.991	0.008
C76.5 Lower limb	0.000	0.991	0.008
C76.4 Upper limb	0.000	0.991	0.008
E22.0 Acromegaly and pituitary gigantism	0.008	0.992	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.008	0.992	0.000
C76.1 Thorax	0.000	0.992	0.008
E50-E64 Other nutritional deficiencies	0.007	0.992	0.000
D13.1 Stomach	0.008	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.992	0.000
J30.1 Allergic rhinitis due to pollen	0.008	0.992	0.000
E21.0 Primary hyperparathyroidism	0.007	0.993	0.000
C76.2 Abdomen	0.000	0.993	0.007
E22.1 Hyperprolactinaemia	0.007	0.993	0.000
I71 Aortic aneurysm and dissection	0.000	0.993	0.007
E16.2 Hypoglycaemia, unspecified	0.007	0.993	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.994	0.006
E65 Localised adiposity	0.006	0.994	0.001
E21.3 Hyperparathyroidism, unspecified	0.006	0.994	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.994	0.006
K90 Intestinal malabsorption	0.006	0.994	0.000
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
H46 Optic neuritis	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.005	0.995	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.995	0.005
K90.8 Other intestinal malabsorption	0.005	0.995	0.000
E51 Thiamine deficiency	0.005	0.995	0.000
H16.0 Corneal ulcer	0.000	0.995	0.005
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.995	0.005
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.995	0.005
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.995	0.005
M95.0 Acquired deformity of nose	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.005	0.995	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.005
K90.3 Pancreatic steatorrhoea	0.004	0.995	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.004	0.995	0.000
K90.1 Tropical sprue	0.004	0.995	0.000
G44.8 Other specified headache syndromes	0.005	0.995	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.996	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.996	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.996	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.996	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.996	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.996	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.996	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.996	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.996	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.996	0.000
E56.8 Deficiency of other vitamins	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.004	0.996	0.000
E56.0 Deficiency of vitamin E	0.004	0.996	0.000
E63.9 Nutritional deficiency, unspecified	0.004	0.996	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.996	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.996	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.996	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.996	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.996	0.000
E64.3 Sequelae of rickets	0.004	0.996	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.996	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.996	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.004	0.996	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.996	0.004
E61 Deficiency of other nutrient elements	0.003	0.996	0.001
E00-E07 Disorders of thyroid gland	0.004	0.996	0.000
M48.0 Spinal stenosis	0.004	0.996	0.000
G44.0 Cluster headache syndrome	0.004	0.996	0.000
E51.9 Thiamine deficiency, unspecified	0.004	0.996	0.000
E51.8 Other manifestations of thiamine deficiency	0.004	0.996	0.000
E51.1 Beriberi	0.004	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
J30 Vasomotor and allergic rhinitis	0.004	0.996	0.000
M48.04 Spinal stenosis (Thoracic region)	0.004	0.996	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.004	0.996	0.000
J39.2 Other diseases of pharynx	0.000	0.996	0.004
J30.4 Allergic rhinitis, unspecified	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
G80.1 Spastic diplegia	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.003	0.996	0.000
E53.0 Riboflavin deficiency	0.003	0.996	0.000
G44 Other headache syndromes	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.003	0.996	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.004	0.996	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.996	0.000
G80.8 Other infantile cerebral palsy	0.003	0.996	0.000
G80 Infantile cerebral palsy	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
M48.00 Spinal stenosis (Multiple sites in spine)	0.003	0.997	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.003	0.997	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.001
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.001
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.001
E61.6 Vanadium deficiency	0.003	0.997	0.001
E61.5 Molybdenum deficiency	0.003	0.997	0.001
E61.4 Chromium deficiency	0.003	0.997	0.001
E61.3 Manganese deficiency	0.003	0.997	0.001
E61.0 Copper deficiency	0.003	0.997	0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
M48.09 Spinal stenosis (Site unspecified)	0.003	0.997	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.003	0.997	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
J30.2 Other seasonal allergic rhinitis	0.003	0.997	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.002	0.997	0.001
R49.8 Other and unspecified voice disturbances	0.003	0.997	0.000
G44.3 Chronic posttraumatic headache	0.003	0.997	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
G44.1 Vascular headache, not elsewhere classified	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.003	0.997	0.000
J30.3 Other allergic rhinitis	0.003	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.003	0.997	0.000
J30.0 Vasomotor rhinitis	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
E06 Thyroiditis	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.003	0.997	0.000
E05.4 Thyrotoxicosis factitia	0.003	0.997	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
I05.0 Mitral stenosis	0.003	0.997	0.000
G80.4 Ataxic cerebral palsy	0.003	0.997	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
G80.2 Infantile hemiplegia	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.997	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.997	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.997	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.997	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.997	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.997	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.997	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
G44.2 Tension-type headache	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.997	0.003
M48.06 Spinal stenosis (Lumbar region)	0.003	0.997	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
S22.2 Fracture of sternum	0.000	0.997	0.002
J18.0 Bronchopneumonia, unspecified	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
I50.9 Heart failure, unspecified	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
E61.1 Iron deficiency	0.001	0.998	0.002
Z50.2 Alcohol rehabilitation	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.998	0.002
N08.3 Glomerular disorders in diabetes mellitus	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
N08 Glomerular disorders in diseases classified elsewhere	0.002	0.998	0.000
S36.1 Injury of liver or gallbladder	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.000	0.998	0.002
G25.3 Myoclonus	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.002
M95.4 Acquired deformity of chest and rib	0.000	0.998	0.002
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
T14.9 Injury, unspecified	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.998	0.002
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.998	0.002
M95.5 Acquired deformity of pelvis	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.998	0.002
M95.3 Acquired deformity of neck	0.000	0.998	0.002
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.002	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
T14.6 Injury of tendons and muscles of unspecified body region	0.002	0.998	0.000
H16 Keratitis	0.000	0.998	0.002
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.998	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.998	0.002
N08.8 Glomerular disorders in other diseases classified elsewhere	0.002	0.998	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.002	0.998	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M95.1 Cauliflower ear	0.000	0.998	0.001
T14 Injury of unspecified body region	0.002	0.998	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.000	0.998	0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.998	0.000
M96.5 Postradiation scoliosis	0.002	0.998	0.000
M96.4 Postsurgical lordosis	0.002	0.998	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.998	0.000
M96.2 Postradiation kyphosis	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
H26.1 Traumatic cataract	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.000	0.998	0.001
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
M48.9 Spondylopathy, unspecified	0.002	0.998	0.000
M48 Other spondylopathies	0.002	0.998	0.000
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.001	0.998	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.001	0.998	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.001	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.000	0.998	0.001
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.001
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.001
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.001
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.001
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.001
U80.0 Penicillin resistant agent	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
S22.5 Flail chest	0.000	0.998	0.001
T14.1 Open wound of unspecified body region	0.001	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
J39 Other diseases of upper respiratory tract	0.000	0.998	0.002
T14.2 Fracture of unspecified body region	0.001	0.998	0.000
T14.8 Other injuries of unspecified body region	0.001	0.998	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.001	0.998	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.001	0.998	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.001	0.998	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.001	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.001	0.998	0.000
U81.0 Vancomycin resistant agent	0.001	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.001	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.001	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.001	0.998	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.998	0.001
M48.92 Spondylopathy, unspecified (Cervical region)	0.001	0.999	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.999	0.001
E03.1 Congenital hypothyroidism without goitre	0.001	0.999	0.000
H16.8 Other keratitis	0.000	0.999	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations