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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8043440
log Bayes Factor = 0.0114729
Chromosome 15   position 26,973,086  (GRCh37) Explore rs8043440 on Ensembl!
Variant rs8043440 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.844 0.156
E11 Non-insulin-dependent diabetes mellitus
0.000 0.872 0.128
E11.2 With renal complications
0.000 0.887 0.113
E11.5 With peripheral circulatory complications
0.000 0.894 0.106
E11.6 With other specified complications
0.000 0.897 0.103
E11.4 With neurological complications
0.000 0.898 0.102
E11.8 With unspecified complications
0.000 0.904 0.096
E11.7 With multiple complications
0.000 0.908 0.092
E11.1 With ketoacidosis
0.000 0.910 0.090
E10-E14 Diabetes mellitus
0.000 0.925 0.075
E11.0 With coma
0.000 0.925 0.074
E14 Unspecified diabetes mellitus
0.000 0.933 0.067
E14.9 Without complications
0.000 0.934 0.066
E12 Malnutrition-related diabetes mellitus
0.000 0.946 0.054
E10 Insulin-dependent diabetes mellitus
0.000 0.947 0.053
E14.7 With multiple complications
0.000 0.952 0.048
E14.6 With other specified complications
0.000 0.952 0.048
E14.5 With peripheral circulatory complications
0.000 0.952 0.048
E14.2 Withrenal complications
0.000 0.952 0.048
E14.0 With coma
0.000 0.952 0.048
E14.4 With neurological complications
0.000 0.953 0.047
E10.2 With renal complications
0.000 0.954 0.046
E14.8 With unspecified complications
0.000 0.954 0.046
E14.1 With ketoacidosis
0.000 0.955 0.045
E10.3 With ophthalmic complications
0.000 0.955 0.045
E11.3 With ophthalmic complications
0.000 0.955 0.045
E13 Other specified diabetes mellitus
0.000 0.955 0.044
E10.4 With neurological complications
0.000 0.957 0.043
E10.1 With ketoacidosis
0.000 0.959 0.041
E10.8 With unspecified complications
0.000 0.961 0.039
E12.9 Without complications
0.000 0.961 0.039
E12.8 With unspecified complications
0.000 0.961 0.039
E12.7 With multiple complications
0.000 0.961 0.039
E12.6 With other specified complications
0.000 0.961 0.039
E12.5 With peripheral circulatory complications
0.000 0.961 0.039
E12.4 With neurological complications
0.000 0.961 0.039
E12.3 With ophthalmic complications
0.000 0.961 0.039
E12.2 With renal complications
0.000 0.961 0.039
E12.1 With ketoacidosis
0.000 0.961 0.039
E12.0 With coma
0.000 0.961 0.039
E10.7 With multiple complications
0.000 0.961 0.038
E10.5 With peripheral circulatory complications
0.000 0.965 0.035
E14.3 With ophthalmic complications
0.000 0.966 0.034
E10.6 With other specified complications
0.000 0.967 0.033
E13.8 With unspecified complications
0.000 0.968 0.032
E13.7 With multiple complications
0.000 0.968 0.032
E13.6 With other specified complications
0.000 0.968 0.032
E13.5 With peripheral circulatory complications
0.000 0.968 0.032
E13.4 With neurological complications
0.000 0.968 0.032
E13.3 With ophthalmic complications
0.000 0.968 0.032
E13.2 With renal complications
0.000 0.968 0.032
E13.1 With ketoacidosis
0.000 0.968 0.032
E13.0 With coma
0.000 0.968 0.032
E10.0 With coma
0.000 0.970 0.030
E13.9 Without complications
0.000 0.977 0.022
E10.9 Without complications
0.000 0.982 0.017
E87.2 Acidosis
0.000 0.990 0.010
F10.2 Dependence syndrome
0.000 0.990 0.010
B37.0 Candidal stomatitis
0.000 0.991 0.009
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.991 0.009
E87.7 Fluid overload
0.000 0.991 0.009
E65-E68 Obesity and other hyperalimentation
0.000 0.992 0.008
R07.2 Precordial pain
0.000 0.993 0.007
R07.1 Chest pain on breathing
0.000 0.993 0.007
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.993 0.007
E66 Obesity
0.000 0.993 0.007
E66.9 Obesity, unspecified
0.000 0.993 0.007
E40-E46 Malnutrition
0.000 0.993 0.006
E70-E90 Metabolic disorders
0.000 0.994 0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.994 0.006
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.000 0.994 0.006
T21 Burn and corrosion of trunk
0.006 0.994 0.000
E67 Other hyperalimentation
0.000 0.994 0.006
E68 Sequelae of hyperalimentation
0.000 0.994 0.006
E65 Localised adiposity
0.000 0.994 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.994 0.006
E20-E35 Disorders of other endocrine glands
0.000 0.994 0.006
E73 Lactose intolerance
0.000 0.994 0.006
T20-T25 Burns and corrosions of external body surface, specified by site
0.006 0.994 0.000
E80.4 Gilbert's syndrome
0.000 0.995 0.005
E66.0 Obesity due to excess calories
0.000 0.995 0.005
E73.9 Lactose intolerance, unspecified
0.000 0.995 0.005
E88 Other metabolic disorders
0.000 0.995 0.005
T23 Burn and corrosion of wrist and hand
0.005 0.995 0.000
E87.3 Alkalosis
0.000 0.995 0.005
T21.0 Burn of unspecified degree of trunk
0.005 0.995 0.000
T21.3 Burn of third degree of trunk
0.005 0.995 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.995 0.005
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.005 0.995 0.000
T21.2 Burn of second degree of trunk
0.005 0.995 0.000
T25 Burn and corrosion of ankle and foot
0.005 0.995 0.000
E66.1 Drug-induced obesity
0.000 0.995 0.005
E00-E07 Disorders of thyroid gland
0.000 0.995 0.005
E26 Hyperaldosteronism
0.000 0.995 0.005
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.995 0.005
E45 Retarded development following protein-energy malnutrition
0.000 0.995 0.005
E43 Unspecified severe protein-energy malnutrition
0.000 0.995 0.005
E42 Marasmic kwashiorkor
0.000 0.995 0.005
E41 Nutritional marasmus
0.000 0.995 0.005
E40 Kwashiorkor
0.000 0.995 0.005
R07 Pain in throat and chest
0.000 0.995 0.005
E23 Hypofunction and other disorders of pituitary gland
0.000 0.995 0.005
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.995 0.005
E85 Amyloidosis
0.000 0.995 0.005
E50-E64 Other nutritional deficiencies
0.001 0.995 0.004
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.995 0.005
T23.2 Burn of second degree of wrist and hand
0.005 0.995 0.000
T25.3 Burn of third degree of ankle and foot
0.005 0.995 0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot
0.005 0.995 0.000
E07 Other disorders of thyroid
0.000 0.995 0.005
E23.0 Hypopituitarism
0.000 0.995 0.005
E15 Nondiabetic hypoglycaemic coma
0.000 0.995 0.004
E84 Cystic fibrosis
0.000 0.995 0.004
E79 Disorders of purine and pyrimidine metabolism
0.000 0.995 0.004
E77 Disorders of glycoprotein metabolism
0.000 0.995 0.004
E76 Disorders of glycosaminoglycan metabolism
0.000 0.995 0.004
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.995 0.004
E72 Other disorders of amino-acid metabolism
0.000 0.995 0.004
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.995 0.004
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.995 0.004
E29 Testicular dysfunction
0.000 0.995 0.005
E46 Unspecified protein-energy malnutrition
0.000 0.995 0.004
E87.0 Hyperosmolality and hypernatraemia
0.000 0.995 0.004
T23.3 Burn of third degree of wrist and hand
0.004 0.995 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.004 0.995 0.000
E26.0 Primary hyperaldosteronism
0.000 0.995 0.004
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.995 0.004
E55.9 Vitamin D deficiency, unspecified
0.004 0.995 0.000
T21.7 Corrosion of third degree of trunk
0.004 0.996 0.000
T21.6 Corrosion of second degree of trunk
0.004 0.996 0.000
T21.5 Corrosion of first degree of trunk
0.004 0.996 0.000
T21.4 Corrosion of unspecified degree of trunk
0.004 0.996 0.000
T21.1 Burn of first degree of trunk
0.004 0.996 0.000
E22 Hyperfunction of pituitary gland
0.000 0.996 0.004
E67.8 Other specified hyperalimentation
0.000 0.996 0.004
E67.3 Hypervitaminosis D
0.000 0.996 0.004
E67.2 Megavitamin-B6 syndrome
0.000 0.996 0.004
E67.1 Hypercarotenaemia
0.000 0.996 0.004
E67.0 Hypervitaminosis A
0.000 0.996 0.004
E24 Cushing's syndrome
0.000 0.996 0.004
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.996 0.004
E80.6 Other disorders of bilirubin metabolism
0.000 0.996 0.004
E80.5 Crigler-Najjar syndrome
0.000 0.996 0.004
E80.3 Defects of catalase and peroxydase
0.000 0.996 0.004
E80.2 Other porphyria
0.000 0.996 0.004
E80.1 Porphyria cutanea tarda
0.000 0.996 0.004
E80.0 Hereditary erythropoietic porphyria
0.000 0.996 0.004
T20 Burn and corrosion of head and neck
0.004 0.996 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.996 0.004
E32 Diseases of thymus
0.000 0.996 0.004
E31 Polyglandular dysfunction
0.000 0.996 0.004
E30 Disorders of puberty, not elsewhere classified
0.000 0.996 0.004
E25 Adrenogenital disorders
0.000 0.996 0.004
E73.8 Other lactose intolerance
0.000 0.996 0.004
E73.1 Secondary lactase deficiency
0.000 0.996 0.004
E73.0 Congenital lactase deficiency
0.000 0.996 0.004
E28 Ovarian dysfunction
0.000 0.996 0.004
E85.9 Amyloidosis, unspecified
0.000 0.996 0.004
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.004
B37 Candidiasis
0.000 0.996 0.004
E22.1 Hyperprolactinaemia
0.000 0.996 0.004
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.996 0.004
E07.8 Other specified disorders of thyroid
0.000 0.996 0.004
T23.0 Burn of unspecified degree of wrist and hand
0.004 0.996 0.000
E23.6 Other disorders of pituitary gland
0.000 0.996 0.004
R07.3 Other chest pain
0.000 0.996 0.004
E55 Vitamin D deficiency
0.002 0.996 0.002
E34 Other endocrine disorders
0.000 0.996 0.004
E88.9 Metabolic disorder, unspecified
0.000 0.996 0.004
E88.8 Other specified metabolic disorders
0.000 0.996 0.004
E88.3 Tumour lysis syndrome
0.000 0.996 0.004
E88.2 Lipomatosis, not elsewhere classified
0.000 0.996 0.004
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.996 0.004
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand
0.004 0.996 0.000
T23.7 Corrosion of third degree of wrist and hand
0.004 0.996 0.000
T23.6 Corrosion of second degree of wrist and hand
0.004 0.996 0.000
T23.5 Corrosion of first degree of wrist and hand
0.004 0.996 0.000
T23.4 Corrosion of unspecified degree of wrist and hand
0.004 0.996 0.000
T23.1 Burn of first degree of wrist and hand
0.004 0.996 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
L40.9 Psoriasis, unspecified
0.004 0.996 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.996 0.004
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
E06 Thyroiditis
0.000 0.996 0.004
T25.7 Corrosion of third degree of ankle and foot
0.004 0.996 0.000
T25.6 Corrosion of second degree of ankle and foot
0.004 0.996 0.000
T25.5 Corrosion of first degree of ankle and foot
0.004 0.996 0.000
T25.4 Corrosion of unspecified degree of ankle and foot
0.004 0.996 0.000
T25.2 Burn of second degree of ankle and foot
0.004 0.996 0.000
T25.1 Burn of first degree of ankle and foot
0.004 0.996 0.000
T25.0 Burn of unspecified degree of ankle and foot
0.004 0.996 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.996 0.004
E00 Congenital iodine-deficiency syndrome
0.000 0.996 0.004
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.996 0.004
E20 Hypoparathyroidism
0.000 0.996 0.004
E26.9 Hyperaldosteronism, unspecified
0.000 0.996 0.004
E26.8 Other hyperaldosteronism
0.000 0.996 0.004
E26.1 Secondary hyperaldosteronism
0.000 0.996 0.004
E29.1 Testicular hypofunction
0.000 0.996 0.004
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.004 0.996 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.996 0.004
E44.0 Moderate protein-energy malnutrition
0.000 0.996 0.004
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.996 0.004
E23.1 Drug-induced hypopituitarism
0.000 0.996 0.004
E28.3 Primary ovarian failure
0.000 0.996 0.004
E85.8 Other amyloidosis
0.000 0.996 0.004
E85.3 Secondary systemic amyloidosis
0.000 0.996 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.996 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.996 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.996 0.004
E16 Other disorders of pancreatic internal secretion
0.000 0.996 0.004
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.996 0.003
E63 Other nutritional deficiencies
0.001 0.996 0.003
E61 Deficiency of other nutrient elements
0.001 0.996 0.003
E56 Other vitamin deficiencies
0.001 0.996 0.003
E51 Thiamine deficiency
0.001 0.996 0.003
E50 Vitamin A deficiency
0.001 0.996 0.003
E60 Dietary zinc deficiency
0.001 0.996 0.003
E59 Dietary selenium deficiency
0.001 0.996 0.003
E58 Dietary calcium deficiency
0.001 0.996 0.003
E54 Ascorbic acid deficiency
0.001 0.996 0.003
E52 Niacin deficiency [pellagra]
0.001 0.996 0.003
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.996 0.004
E66.8 Other obesity
0.000 0.996 0.004
E24.9 Cushing's syndrome, unspecified
0.000 0.996 0.004
G81.9 Hemiplegia, unspecified
0.000 0.996 0.004
T20.1 Burn of first degree of head and neck
0.003 0.996 0.000
E07.1 Dyshormogenetic goitre
0.000 0.996 0.003
E07.0 Hypersecretion of calcitonin
0.000 0.996 0.003
E71.3 Disorders of fatty-acid metabolism
0.000 0.996 0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.996 0.003
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.996 0.003
E71.0 Maple-syrup-urine disease
0.000 0.996 0.003
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.996 0.003
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.996 0.003
E72.5 Disorders of glycine metabolism
0.000 0.996 0.003
E72.4 Disorders of ornithine metabolism
0.000 0.996 0.003
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.996 0.003
E72.2 Disorders of urea cycle metabolism
0.000 0.996 0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.996 0.003
E72.0 Disorders of amino-acid transport
0.000 0.996 0.003
E75.6 Lipid storage disorder, unspecified
0.000 0.996 0.003
E75.5 Other lipid storage disorders
0.000 0.996 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.996 0.003
E75.3 Sphingolipidosis, unspecified
0.000 0.996 0.003
E75.2 Other sphingolipidosis
0.000 0.996 0.003
E75.1 Other gangliosidosis
0.000 0.996 0.003
E75.0 GM2 gangliosidosis
0.000 0.996 0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.996 0.003
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.996 0.003
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.996 0.003
E76.2 Other mucopolysaccharidoses
0.000 0.996 0.003
E76.1 Mucopolysaccharidosis, type II
0.000 0.996 0.003
E76.0 Mucopolysaccharidosis, type I
0.000 0.996 0.003
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.996 0.003
E77.8 Other disorders of glycoprotein metabolism
0.000 0.996 0.003
E77.1 Defects in glycoprotein degradation
0.000 0.996 0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.996 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.996 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.996 0.003
E79.1 Lesch-Nyhan syndrome
0.000 0.996 0.003
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.996 0.003
E84.9 Cystic fibrosis, unspecified
0.000 0.996 0.003
E84.8 Cystic fibrosis with other manifestations
0.000 0.996 0.003
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.996 0.003
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.996 0.003
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.996 0.004
E29.9 Testicular dysfunction, unspecified
0.000 0.996 0.003
E29.8 Other testicular dysfunction
0.000 0.996 0.003
E29.0 Testicular hyperfunction
0.000 0.996 0.003
E23.7 Disorder of pituitary gland, unspecified
0.000 0.996 0.003
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand
0.003 0.996 0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand
0.003 0.996 0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand
0.003 0.996 0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand
0.003 0.996 0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.003 0.996 0.000
B37.4 Candidiasis of other urogenital sites
0.000 0.996 0.003
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.003 0.997 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.997 0.003
E22.8 Other hyperfunction of pituitary gland
0.000 0.997 0.003
B37.3 Candidiasis of vulva and vagina
0.000 0.997 0.003
E24.8 Other Cushing's syndrome
0.000 0.997 0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.997 0.003
E24.3 Ectopic ACTH syndrome
0.000 0.997 0.003
E24.1 Nelson's syndrome
0.000 0.997 0.003
E24.0 Pituitary-dependent Cushing's disease
0.000 0.997 0.003
E25.9 Adrenogenital disorder, unspecified
0.000 0.997 0.003
E25.8 Other adrenogenital disorders
0.000 0.997 0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.997 0.003
E30.9 Disorder of puberty, unspecified
0.000 0.997 0.003
E30.8 Other disorders of puberty
0.000 0.997 0.003
E30.1 Precocious puberty
0.000 0.997 0.003
E30.0 Delayed puberty
0.000 0.997 0.003
E31.9 Polyglandular dysfunction, unspecified
0.000 0.997 0.003
E31.8 Other polyglandular dysfunction
0.000 0.997 0.003
E31.1 Polyglandular hyperfunction
0.000 0.997 0.003
E31.0 Autoimmune polyglandular failure
0.000 0.997 0.003
E32.9 Disease of thymus, unspecified
0.000 0.997 0.003
E32.8 Other diseases of thymus
0.000 0.997 0.003
E32.1 Abscess of thymus
0.000 0.997 0.003
E32.0 Persistent hyperplasia of thymus
0.000 0.997 0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.997 0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.997 0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.997 0.003
T20.7 Corrosion of third degree of head and neck
0.003 0.997 0.000
T20.6 Corrosion of second degree of head and neck
0.003 0.997 0.000
T20.5 Corrosion of first degree of head and neck
0.003 0.997 0.000
T20.4 Corrosion of unspecified degree of head and neck
0.003 0.997 0.000
T20.3 Burn of third degree of head and neck
0.003 0.997 0.000
T20.0 Burn of unspecified degree of head and neck
0.003 0.997 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.997 0.003
E28.8 Other ovarian dysfunction
0.000 0.997 0.003
E28.1 Androgen excess
0.000 0.997 0.003
E28.0 Oestrogen excess
0.000 0.997 0.003
E06.9 Thyroiditis, unspecified
0.000 0.997 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
E74.0 Glycogen storage disease
0.000 0.997 0.003
E85.4 Organ-limited amyloidosis
0.000 0.997 0.003
B37.7 Candidal septicaemia
0.000 0.997 0.003
B37.6 Candidal endocarditis
0.000 0.997 0.003
B37.5 Candidal meningitis
0.000 0.997 0.003
B37.2 Candidiasis of skin and nail
0.000 0.997 0.003
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.003 0.997 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.997 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
E70.2 Disorders of tyrosine metabolism
0.000 0.997 0.003
E70.1 Other hyperphenylalaninaemias
0.000 0.997 0.003
E70.0 Classical phenylketonuria
0.000 0.997 0.003
E55.0 Rickets, active
0.002 0.997 0.001
E04 Other non-toxic goitre
0.000 0.997 0.003
E34.5 Androgen resistance syndrome
0.000 0.997 0.003
E34.4 Constitutional tall stature
0.000 0.997 0.003
E34.3 Short stature, not elsewhere classified
0.000 0.997 0.003
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.997 0.003
E34.1 Other hypersecretion of intestinal hormones
0.000 0.997 0.003
E23.2 Diabetes insipidus
0.000 0.997 0.003
E34.0 Carcinoid syndrome
0.000 0.997 0.003
B37.8 Candidiasis of other sites
0.000 0.997 0.003
E24.2 Drug-induced Cushing's syndrome
0.000 0.997 0.003
T20.2 Burn of second degree of head and neck
0.003 0.997 0.000
E06.5 Other chronic thyroiditis
0.000 0.997 0.003
E06.4 Drug-induced thyroiditis
0.000 0.997 0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.997 0.003
E06.1 Subacute thyroiditis
0.000 0.997 0.003
E06.0 Acute thyroiditis
0.000 0.997 0.003
E04.1 Non-toxic single thyroid nodule
0.000 0.997 0.003
E20.8 Other hypoparathyroidism
0.000 0.997 0.003
E20.1 Pseudohypoparathyroidism
0.000 0.997 0.003
E20.0 Idiopathic hypoparathyroidism
0.000 0.997 0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.997 0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.997 0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.997 0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.997 0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.997 0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.997 0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.997 0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.997 0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.997 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
I69.3 Sequelae of cerebral infarction
0.000 0.997 0.003
B37.1 Pulmonary candidiasis
0.000 0.997 0.003
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.997 0.003
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.997 0.003
E16.4 Abnormal secretion of gastrin
0.000 0.997 0.003
E16.3 Increased secretion of glucagon
0.000 0.997 0.003
E50.9 Vitamin A deficiency, unspecified
0.001 0.997 0.002
E50.8 Other manifestations of vitamin A deficiency
0.001 0.997 0.002
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.997 0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.997 0.002
E50.5 Vitamin A deficiency with night blindness
0.001 0.997 0.002
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.997 0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.997 0.002
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.997 0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.997 0.002
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.997 0.002
E51.9 Thiamine deficiency, unspecified
0.001 0.997 0.002
E51.8 Other manifestations of thiamine deficiency
0.001 0.997 0.002
E51.2 Wernicke's encephalopathy
0.001 0.997 0.002
E51.1 Beriberi
0.001 0.997 0.002
E56.9 Vitamin deficiency, unspecified
0.001 0.997 0.002
E56.8 Deficiency of other vitamins
0.001 0.997 0.002
E56.1 Deficiency of vitamin K
0.001 0.997 0.002
E56.0 Deficiency of vitamin E
0.001 0.997 0.002
E61.9 Deficiency of nutrient element, unspecified
0.001 0.997 0.002
E61.8 Deficiency of other specified nutrient elements
0.001 0.997 0.002
E61.7 Deficiency of multiple nutrient elements
0.001 0.997 0.002
E61.6 Vanadium deficiency
0.001 0.997 0.002
E61.5 Molybdenum deficiency
0.001 0.997 0.002
E61.4 Chromium deficiency
0.001 0.997 0.002
E61.3 Manganese deficiency
0.001 0.997 0.002
E61.2 Magnesium deficiency
0.001 0.997 0.002
E61.0 Copper deficiency
0.001 0.997 0.002
E63.9 Nutritional deficiency, unspecified
0.001 0.997 0.002
E63.8 Other specified nutritional deficiencies
0.001 0.997 0.002
E63.1 Imbalance of constituents of food intake
0.001 0.997 0.002
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.997 0.002
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.997 0.002
E64.8 Sequelae of other nutritional deficiencies
0.001 0.997 0.002
E64.3 Sequelae of rickets
0.001 0.997 0.002
E64.2 Sequelae of vitamin C deficiency
0.001 0.997 0.002
E64.1 Sequelae of vitamin A deficiency
0.001 0.997 0.002
E64.0 Sequelae of protein-energy malnutrition
0.001 0.997 0.002
E61.1 Iron deficiency
0.000 0.997 0.003
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.997 0.003
E34.8 Other specified endocrine disorders
0.000 0.997 0.003
E70.3 Albinism
0.000 0.997 0.003
M13.97 Arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
E16.1 Other hypoglycaemia
0.000 0.997 0.003
L50.9 Urticaria, unspecified
0.000 0.997 0.003
M54.56 Low back pain (Lumbar region)
0.000 0.997 0.003
E04.0 Non-toxic diffuse goitre
0.000 0.997 0.003
I44.2 Atrioventricular block, complete
0.000 0.997 0.003
E06.3 Autoimmune thyroiditis
0.000 0.997 0.003
E22.0 Acromegaly and pituitary gigantism
0.000 0.997 0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.997 0.002
E28.2 Polycystic ovarian syndrome
0.000 0.997 0.003
T81.3 Disruption of operation wound, not elsewhere classified
0.000 0.997 0.003
R07.0 Pain in throat
0.000 0.997 0.003
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.997 0.003
E53 Deficiency of other B group vitamins
0.001 0.997 0.002
E20.9 Hypoparathyroidism, unspecified
0.000 0.997 0.002
E04.8 Other specified non-toxic goitre
0.000 0.997 0.002
M43.16 Spondylolisthesis (Lumbar region)
0.003 0.997 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.997 0.003
T31.0 Burns involving less than 10% of body surface
0.003 0.997 0.000
B37.9 Candidiasis, unspecified
0.000 0.997 0.002
I69 Sequelae of cerebrovascular disease
0.000 0.998 0.002
M95.0 Acquired deformity of nose
0.002 0.998 0.000
L40.0 Psoriasis vulgaris
0.002 0.998 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
L98.0 Pyogenic granuloma
0.002 0.998 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.998 0.002
F20.0 Paranoid schizophrenia
0.002 0.998 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.002 0.998 0.000
E27 Other disorders of adrenal gland
0.000 0.998 0.002
M65.34 Trigger finger-Hand
0.002 0.998 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.998 0.002
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.998 0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.998 0.002
E89.5 Postprocedural testicular hypofunction
0.000 0.998 0.002
E89.4 Postprocedural ovarian failure
0.000 0.998 0.002
E89.1 Postprocedural hypoinsulinaemia
0.000 0.998 0.002
L40 Psoriasis
0.002 0.998 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.998 0.002
E87.5 Hyperkalaemia
0.000 0.998 0.002
E53.1 Pyridoxine deficiency
0.001 0.998 0.002
E53.0 Riboflavin deficiency
0.001 0.998 0.002
E05.8 Other thyrotoxicosis
0.000 0.998 0.002
E05.5 Thyroid crisis or storm
0.000 0.998 0.002
E05.4 Thyrotoxicosis factitia
0.000 0.998 0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.998 0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.998 0.002
Z29.2 Other prophylactic chemotherapy
0.000 0.998 0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.998 0.002
E03 Other hypothyroidism
0.000 0.998 0.002
G81 Hemiplegia
0.000 0.998 0.002
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.998 0.002
E21.4 Other specified disorders of parathyroid gland
0.000 0.998 0.002
E21.2 Other hyperparathyroidism
0.000 0.998 0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.002 0.998 0.000
E53.9 Vitamin B deficiency, unspecified
0.001 0.998 0.002
Z29.0 Isolation
0.000 0.998 0.002
S32.50 Fracture of pubis (closed)
0.002 0.998 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.002 0.998 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.998 0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.998 0.002
R22.9 Localised swelling, mass and lump, unspecified
0.002 0.998 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.998 0.002
M07.3 Other psoriatic arthropathies
0.000 0.998 0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.002 0.998 0.000
M43.1 Spondylolisthesis
0.002 0.998 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.002 0.998 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.998 0.002
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.998 0.002
E27.0 Other adrenocortical overactivity
0.000 0.998 0.002
I63.9 Cerebral infarction, unspecified
0.000 0.998 0.002
E86 Volume depletion
0.000 0.998 0.002
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.998 0.002
L40.8 Other psoriasis
0.002 0.998 0.000
Z48.8 Other specified surgical follow-up care
0.002 0.998 0.000
L40.4 Guttate psoriasis
0.002 0.998 0.000
L40.3 Pustulosis palmaris et plantaris
0.002 0.998 0.000
L40.2 Acrodermatitis continua
0.002 0.998 0.000
L40.1 Generalised pustular psoriasis
0.002 0.998 0.000
A04.8 Other specified bacterial intestinal infections
0.002 0.998 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.998 0.002
L30.9 Dermatitis, unspecified
0.000 0.998 0.002
E03.5 Myxoedema coma
0.000 0.998 0.002
E03.4 Atrophy of thyroid (acquired)
0.000 0.998 0.002
E03.3 Postinfectious hypothyroidism
0.000 0.998 0.002
E03.1 Congenital hypothyroidism without goitre
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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