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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs805286
log Bayes Factor = 7.68152
Chromosome 6   position 31,679,307  (GRCh37) Explore rs805286 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.037 0.963
E03 Other hypothyroidism
0.000 0.257 0.743
K50 Crohn's disease [regional enteritis]
0.599 0.401 0.000
K50.1 Crohn's disease of large intestine
0.594 0.406 0.000
K50.0 Crohn's disease of small intestine
0.586 0.414 0.000
E00-E07 Disorders of thyroid gland
0.000 0.419 0.581
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.419 0.581
K50.9 Crohn's disease, unspecified
0.579 0.421 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.439 0.561
E05.9 Thyrotoxicosis, unspecified
0.000 0.459 0.541
E03.5 Myxoedema coma
0.000 0.467 0.533
E03.4 Atrophy of thyroid (acquired)
0.000 0.467 0.533
E03.3 Postinfectious hypothyroidism
0.000 0.467 0.533
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.467 0.533
E03.1 Congenital hypothyroidism without goitre
0.000 0.470 0.530
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.490 0.510
K50.8 Other Crohn's disease
0.495 0.505 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.506 0.494
E03.8 Other specified hypothyroidism
0.000 0.516 0.484
E27 Other disorders of adrenal gland
0.000 0.523 0.477
E20-E35 Disorders of other endocrine glands
0.000 0.548 0.452
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.574 0.425
E27.2 Addisonian crisis
0.000 0.576 0.424
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.583 0.416
E00 Congenital iodine-deficiency syndrome
0.000 0.583 0.416
E05.8 Other thyrotoxicosis
0.000 0.597 0.403
E05.5 Thyroid crisis or storm
0.000 0.597 0.403
E05.4 Thyrotoxicosis factitia
0.000 0.597 0.403
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.597 0.403
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.597 0.403
E34 Other endocrine disorders
0.000 0.609 0.391
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.610 0.390
E20 Hypoparathyroidism
0.000 0.616 0.384
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.627 0.373
E28 Ovarian dysfunction
0.000 0.637 0.362
K50-K52 Noninfective enteritis and colitis
0.356 0.644 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.649 0.351
E23 Hypofunction and other disorders of pituitary gland
0.000 0.654 0.345
E27.5 Adrenomedullary hyperfunction
0.000 0.658 0.342
E27.0 Other adrenocortical overactivity
0.000 0.658 0.342
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.659 0.341
E26 Hyperaldosteronism
0.000 0.660 0.340
E20.9 Hypoparathyroidism, unspecified
0.000 0.664 0.336
E07 Other disorders of thyroid
0.000 0.669 0.331
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.676 0.324
E32 Diseases of thymus
0.000 0.676 0.324
E31 Polyglandular dysfunction
0.000 0.676 0.324
E30 Disorders of puberty, not elsewhere classified
0.000 0.676 0.324
E06 Thyroiditis
0.000 0.676 0.323
E29 Testicular dysfunction
0.000 0.684 0.316
E27.8 Other specified disorders of adrenal gland
0.000 0.690 0.310
K52 Other non-infective gastro-enteritis and colitis
0.308 0.692 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.701 0.299
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.701 0.299
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.701 0.299
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.701 0.299
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.701 0.299
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.701 0.299
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.701 0.299
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.701 0.299
E28.3 Primary ovarian failure
0.000 0.709 0.291
E22 Hyperfunction of pituitary gland
0.000 0.713 0.287
K90 Intestinal malabsorption
0.000 0.715 0.285
E23.0 Hypopituitarism
0.000 0.716 0.284
E34.5 Androgen resistance syndrome
0.000 0.720 0.280
E34.4 Constitutional tall stature
0.000 0.720 0.280
E34.3 Short stature, not elsewhere classified
0.000 0.720 0.280
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.720 0.280
E34.1 Other hypersecretion of intestinal hormones
0.000 0.720 0.280
E25 Adrenogenital disorders
0.000 0.720 0.280
E34.0 Carcinoid syndrome
0.000 0.722 0.278
E20.8 Other hypoparathyroidism
0.000 0.724 0.276
E20.1 Pseudohypoparathyroidism
0.000 0.724 0.276
E20.0 Idiopathic hypoparathyroidism
0.000 0.724 0.276
E06.3 Autoimmune thyroiditis
0.000 0.727 0.273
E34.8 Other specified endocrine disorders
0.000 0.728 0.272
E28.2 Polycystic ovarian syndrome
0.000 0.729 0.271
E23.7 Disorder of pituitary gland, unspecified
0.000 0.730 0.270
K52.3 Indeterminate colitis
0.269 0.731 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.268 0.732 0.000
D69.6 Thrombocytopenia, unspecified
0.000 0.734 0.266
E07.8 Other specified disorders of thyroid
0.000 0.734 0.266
E27.9 Disorder of adrenal gland, unspecified
0.000 0.737 0.263
E50-E64 Other nutritional deficiencies
0.000 0.738 0.262
E26.0 Primary hyperaldosteronism
0.000 0.739 0.261
K52.0 Gastro-enteritis and colitis due to radiation
0.260 0.739 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.740 0.260
E28.8 Other ovarian dysfunction
0.000 0.740 0.260
E28.1 Androgen excess
0.000 0.740 0.260
E28.0 Oestrogen excess
0.000 0.740 0.260
K51 Ulcerative colitis
0.254 0.746 0.000
K52.1 Toxic gastro-enteritis and colitis
0.251 0.749 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.752 0.248
E23.1 Drug-induced hypopituitarism
0.000 0.752 0.248
E04 Other non-toxic goitre
0.000 0.754 0.246
E24 Cushing's syndrome
0.000 0.754 0.245
E26.9 Hyperaldosteronism, unspecified
0.000 0.756 0.244
E26.8 Other hyperaldosteronism
0.000 0.756 0.244
E26.1 Secondary hyperaldosteronism
0.000 0.756 0.244
E07.1 Dyshormogenetic goitre
0.000 0.763 0.237
E07.0 Hypersecretion of calcitonin
0.000 0.763 0.237
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.763 0.237
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.763 0.237
D69 Purpura and other haemorrhagic conditions
0.000 0.764 0.236
E30.9 Disorder of puberty, unspecified
0.000 0.768 0.232
E30.8 Other disorders of puberty
0.000 0.768 0.232
E30.1 Precocious puberty
0.000 0.768 0.232
E30.0 Delayed puberty
0.000 0.768 0.232
E31.9 Polyglandular dysfunction, unspecified
0.000 0.768 0.232
E31.8 Other polyglandular dysfunction
0.000 0.768 0.232
E31.1 Polyglandular hyperfunction
0.000 0.768 0.232
E31.0 Autoimmune polyglandular failure
0.000 0.768 0.232
E32.9 Disease of thymus, unspecified
0.000 0.768 0.232
E32.8 Other diseases of thymus
0.000 0.768 0.232
E32.1 Abscess of thymus
0.000 0.768 0.232
E32.0 Persistent hyperplasia of thymus
0.000 0.768 0.232
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.768 0.232
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.768 0.232
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.768 0.232
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.768 0.232
E06.4 Drug-induced thyroiditis
0.000 0.768 0.232
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.768 0.232
E06.0 Acute thyroiditis
0.000 0.768 0.232
E53 Deficiency of other B group vitamins
0.000 0.769 0.231
K51.3 Ulcerative (chronic) rectosigmoiditis
0.228 0.772 0.000
E23.2 Diabetes insipidus
0.000 0.773 0.227
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.773 0.227
E29.9 Testicular dysfunction, unspecified
0.000 0.773 0.226
E29.8 Other testicular dysfunction
0.000 0.773 0.226
E29.0 Testicular hyperfunction
0.000 0.773 0.226
E40-E46 Malnutrition
0.001 0.775 0.224
K51.2 Ulcerative (chronic) proctitis
0.220 0.780 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.780 0.220
E53.8 Deficiency of other specified B group vitamins
0.000 0.781 0.219
E29.1 Testicular hypofunction
0.000 0.782 0.218
E23.6 Other disorders of pituitary gland
0.000 0.784 0.216
E65-E68 Obesity and other hyperalimentation
0.000 0.786 0.214
E06.1 Subacute thyroiditis
0.000 0.792 0.207
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.794 0.206
E22.8 Other hyperfunction of pituitary gland
0.000 0.794 0.206
K90.3 Pancreatic steatorrhoea
0.000 0.795 0.204
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.795 0.204
K90.1 Tropical sprue
0.000 0.795 0.204
E22.0 Acromegaly and pituitary gigantism
0.000 0.799 0.201
E25.9 Adrenogenital disorder, unspecified
0.000 0.799 0.201
E25.8 Other adrenogenital disorders
0.000 0.799 0.201
E04.0 Non-toxic diffuse goitre
0.000 0.799 0.201
L43.9 Lichen planus, unspecified
0.198 0.802 0.000
K51.5 Mucosal proctocolitis
0.198 0.802 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.803 0.197
E24.2 Drug-induced Cushing's syndrome
0.000 0.808 0.191
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.812 0.188
E63 Other nutritional deficiencies
0.000 0.812 0.188
E56 Other vitamin deficiencies
0.000 0.812 0.188
E51 Thiamine deficiency
0.000 0.812 0.188
E50 Vitamin A deficiency
0.000 0.812 0.188
E60 Dietary zinc deficiency
0.000 0.812 0.188
E59 Dietary selenium deficiency
0.000 0.812 0.188
E54 Ascorbic acid deficiency
0.000 0.812 0.188
E52 Niacin deficiency [pellagra]
0.000 0.812 0.188
D69.0 Allergic purpura
0.000 0.813 0.187
E22.1 Hyperprolactinaemia
0.000 0.815 0.185
L43 Lichen planus
0.184 0.816 0.000
D69.2 Other nonthrombocytopenic purpura
0.000 0.817 0.183
E04.9 Non-toxic goitre, unspecified
0.000 0.817 0.183
D69.4 Other primary thrombocytopenia
0.000 0.819 0.181
E06.5 Other chronic thyroiditis
0.001 0.819 0.180
L40.5 Arthropathic psoriasis
0.179 0.821 0.000
L40 Psoriasis
0.178 0.822 0.000
E04.8 Other specified non-toxic goitre
0.000 0.823 0.177
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.176 0.824 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.176 0.824 0.000
E24.8 Other Cushing's syndrome
0.000 0.824 0.176
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.824 0.176
E24.3 Ectopic ACTH syndrome
0.000 0.824 0.176
E24.1 Nelson's syndrome
0.000 0.824 0.176
L40-L45 Papulosquamous disorders
0.175 0.825 0.000
D69.5 Secondary thrombocytopenia
0.000 0.825 0.175
E10 Insulin-dependent diabetes mellitus
0.173 0.827 0.000
E10.4 With neurological complications
0.172 0.828 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.830 0.170
D69.8 Other specified haemorrhagic conditions
0.000 0.830 0.169
E53.1 Pyridoxine deficiency
0.000 0.834 0.165
E53.0 Riboflavin deficiency
0.000 0.834 0.165
K51.4 Pseudopolyposis of colon
0.163 0.837 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.162 0.838 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.838 0.161
E45 Retarded development following protein-energy malnutrition
0.001 0.838 0.161
E43 Unspecified severe protein-energy malnutrition
0.001 0.838 0.161
E42 Marasmic kwashiorkor
0.001 0.838 0.161
E41 Nutritional marasmus
0.001 0.838 0.161
E40 Kwashiorkor
0.001 0.838 0.161
E65 Localised adiposity
0.000 0.840 0.160
E10.9 Without complications
0.160 0.840 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.842 0.158
E21.2 Other hyperparathyroidism
0.000 0.842 0.158
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.843 0.157
E55 Vitamin D deficiency
0.000 0.844 0.156
E06.9 Thyroiditis, unspecified
0.001 0.845 0.154
E58 Dietary calcium deficiency
0.001 0.846 0.154
K90.8 Other intestinal malabsorption
0.000 0.846 0.154
E67 Other hyperalimentation
0.000 0.846 0.154
E68 Sequelae of hyperalimentation
0.000 0.846 0.154
E10.3 With ophthalmic complications
0.154 0.846 0.000
E21.0 Primary hyperparathyroidism
0.000 0.847 0.153
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.847 0.152
E10.0 With coma
0.151 0.849 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.850 0.150
J45.9 Asthma, unspecified
0.000 0.850 0.150
E10.5 With peripheral circulatory complications
0.146 0.854 0.000
L40.4 Guttate psoriasis
0.146 0.854 0.000
D69.1 Qualitative platelet defects
0.000 0.856 0.144
E10.2 With renal complications
0.143 0.857 0.000
E10-E14 Diabetes mellitus
0.128 0.857 0.014
D69.9 Haemorrhagic condition, unspecified
0.000 0.859 0.141
L40.1 Generalised pustular psoriasis
0.137 0.863 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.865 0.135
E50.9 Vitamin A deficiency, unspecified
0.000 0.865 0.135
E50.8 Other manifestations of vitamin A deficiency
0.000 0.865 0.135
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.865 0.135
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.865 0.135
E50.5 Vitamin A deficiency with night blindness
0.000 0.865 0.135
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.865 0.135
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.865 0.135
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.865 0.135
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.865 0.135
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.865 0.135
E51.9 Thiamine deficiency, unspecified
0.000 0.865 0.135
E51.8 Other manifestations of thiamine deficiency
0.000 0.865 0.135
E51.2 Wernicke's encephalopathy
0.000 0.865 0.135
E51.1 Beriberi
0.000 0.865 0.135
E56.9 Vitamin deficiency, unspecified
0.000 0.865 0.135
E56.8 Deficiency of other vitamins
0.000 0.865 0.135
E56.1 Deficiency of vitamin K
0.000 0.865 0.135
E56.0 Deficiency of vitamin E
0.000 0.865 0.135
E63.9 Nutritional deficiency, unspecified
0.000 0.865 0.135
E63.8 Other specified nutritional deficiencies
0.000 0.865 0.135
E63.1 Imbalance of constituents of food intake
0.000 0.865 0.135
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.865 0.135
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.865 0.135
E64.8 Sequelae of other nutritional deficiencies
0.000 0.865 0.135
E64.3 Sequelae of rickets
0.000 0.865 0.135
E64.2 Sequelae of vitamin C deficiency
0.000 0.865 0.135
E64.1 Sequelae of vitamin A deficiency
0.000 0.865 0.135
E64.0 Sequelae of protein-energy malnutrition
0.000 0.865 0.135
K51.8 Other ulcerative colitis
0.134 0.865 0.000
L40.9 Psoriasis, unspecified
0.133 0.867 0.000
L43.3 Subacute (active) lichen planus
0.132 0.868 0.000
L43.2 Lichenoid drug reaction
0.132 0.868 0.000
L43.1 Bullous lichen planus
0.132 0.868 0.000
L43.0 Hypertrophic lichen planus
0.132 0.868 0.000
L43.8 Other lichen planus
0.130 0.870 0.000
E13 Other specified diabetes mellitus
0.122 0.871 0.007
E61 Deficiency of other nutrient elements
0.000 0.871 0.129
E10.6 With other specified complications
0.128 0.872 0.000
L40.3 Pustulosis palmaris et plantaris
0.127 0.872 0.000
L40.2 Acrodermatitis continua
0.127 0.872 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.873 0.126
L44 Other papulosquamous disorders
0.126 0.874 0.000
L41 Parapsoriasis
0.126 0.874 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.126 0.874 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.875 0.125
L40.8 Other psoriasis
0.125 0.875 0.000
L42 Pityriasis rosea
0.124 0.876 0.000
E10.7 With multiple complications
0.124 0.876 0.000
E13.9 Without complications
0.119 0.880 0.001
E44.1 Mild protein-energy malnutrition
0.001 0.884 0.116
E44.0 Moderate protein-energy malnutrition
0.001 0.884 0.116
E55.0 Rickets, active
0.000 0.888 0.112
E67.8 Other specified hyperalimentation
0.000 0.889 0.110
E67.3 Hypervitaminosis D
0.000 0.889 0.110
E67.2 Megavitamin-B6 syndrome
0.000 0.889 0.110
E67.1 Hypercarotenaemia
0.000 0.889 0.110
E67.0 Hypervitaminosis A
0.000 0.889 0.110
E53.9 Vitamin B deficiency, unspecified
0.001 0.890 0.110
L40.0 Psoriasis vulgaris
0.110 0.890 0.000
E10.1 With ketoacidosis
0.106 0.894 0.000
R31 Unspecified haematuria
0.105 0.895 0.000
E12 Malnutrition-related diabetes mellitus
0.092 0.897 0.010
E16 Other disorders of pancreatic internal secretion
0.000 0.898 0.102
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.907 0.093
E13.8 With unspecified complications
0.088 0.907 0.005
E13.7 With multiple complications
0.088 0.907 0.005
E13.6 With other specified complications
0.088 0.907 0.005
E13.5 With peripheral circulatory complications
0.088 0.907 0.005
E13.4 With neurological complications
0.088 0.907 0.005
E13.3 With ophthalmic complications
0.088 0.907 0.005
E13.2 With renal complications
0.088 0.907 0.005
E13.1 With ketoacidosis
0.088 0.907 0.005
E13.0 With coma
0.088 0.907 0.005
E61.9 Deficiency of nutrient element, unspecified
0.000 0.907 0.092
E61.8 Deficiency of other specified nutrient elements
0.000 0.907 0.092
E61.7 Deficiency of multiple nutrient elements
0.000 0.907 0.092
E61.6 Vanadium deficiency
0.000 0.907 0.092
E61.5 Molybdenum deficiency
0.000 0.907 0.092
E61.4 Chromium deficiency
0.000 0.907 0.092
E61.3 Manganese deficiency
0.000 0.907 0.092
E61.0 Copper deficiency
0.000 0.907 0.092
E10.8 With unspecified complications
0.092 0.908 0.000
L41.9 Parapsoriasis, unspecified
0.090 0.909 0.000
L41.8 Other parapsoriasis
0.090 0.909 0.000
L41.5 Retiform parapsoriasis
0.090 0.909 0.000
L41.4 Large plaque parapsoriasis
0.090 0.909 0.000
L41.3 Small plaque parapsoriasis
0.090 0.909 0.000
L41.2 Lymphomatoid papulosis
0.090 0.909 0.000
L41.1 Pityriasis lichenoides chronica
0.090 0.909 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.090 0.909 0.000
L44.9 Papulosquamous disorder, unspecified
0.090 0.909 0.000
L44.8 Other specified papulosquamous disorders
0.090 0.909 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.090 0.909 0.000
L44.3 Lichen ruber moniliformis
0.090 0.909 0.000
L44.2 Lichen striatus
0.090 0.909 0.000
L44.1 Lichen nitidus
0.090 0.909 0.000
L44.0 Pityriasis rubra pilaris
0.090 0.909 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.918 0.081
E46 Unspecified protein-energy malnutrition
0.001 0.919 0.081
E55.9 Vitamin D deficiency, unspecified
0.000 0.920 0.080
E11 Non-insulin-dependent diabetes mellitus
0.078 0.921 0.001
E04.2 Non-toxic multinodular goitre
0.000 0.921 0.079
E61.2 Magnesium deficiency
0.001 0.924 0.076
E11.0 With coma
0.074 0.926 0.000
E12.9 Without complications
0.066 0.926 0.008
E12.8 With unspecified complications
0.066 0.926 0.008
E12.7 With multiple complications
0.066 0.926 0.008
E12.6 With other specified complications
0.066 0.926 0.008
E12.5 With peripheral circulatory complications
0.066 0.926 0.008
E12.4 With neurological complications
0.066 0.926 0.008
E12.3 With ophthalmic complications
0.066 0.926 0.008
E12.2 With renal complications
0.066 0.926 0.008
E12.1 With ketoacidosis
0.066 0.926 0.008
E12.0 With coma
0.066 0.926 0.008
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.926 0.073
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.926 0.073
E16.4 Abnormal secretion of gastrin
0.000 0.926 0.073
E16.3 Increased secretion of glucagon
0.000 0.926 0.073
E11.6 With other specified complications
0.072 0.927 0.000
K51.9 Ulcerative colitis, unspecified
0.072 0.928 0.000
E11.4 With neurological complications
0.071 0.929 0.000
E07.9 Disorder of thyroid, unspecified
0.001 0.929 0.071
E16.1 Other hypoglycaemia
0.000 0.929 0.071
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.932 0.068
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.932 0.067
E14 Unspecified diabetes mellitus
0.064 0.934 0.002
J45 Asthma
0.000 0.934 0.066
E61.1 Iron deficiency
0.000 0.936 0.063
H43.3 Other vitreous opacities
0.057 0.943 0.000
E11.7 With multiple complications
0.056 0.943 0.001
H43.8 Other disorders of vitreous body
0.056 0.944 0.000
H43 Disorders of vitreous body
0.055 0.945 0.000
J45.0 Predominantly allergic asthma
0.000 0.945 0.055
D86 Sarcoidosis
0.000 0.946 0.054
E14.8 With unspecified complications
0.052 0.946 0.001
D86.9 Sarcoidosis, unspecified
0.000 0.947 0.053
E11.5 With peripheral circulatory complications
0.053 0.947 0.000
E14.6 With other specified complications
0.050 0.948 0.002
D80-D89 Certain disorders involving the immune mechanism
0.000 0.948 0.052
E14.5 With peripheral circulatory complications
0.049 0.949 0.002
D67 Hereditary factor IX deficiency
0.000 0.951 0.049
D86.0 Sarcoidosis of lung
0.000 0.951 0.049
E14.4 With neurological complications
0.047 0.952 0.002
E14.7 With multiple complications
0.046 0.952 0.002
E14.0 With coma
0.046 0.952 0.002
H43.1 Vitreous haemorrhage
0.048 0.952 0.000
E14.2 Withrenal complications
0.046 0.952 0.002
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.952 0.047
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.953 0.047
E14.1 With ketoacidosis
0.045 0.953 0.002
E66 Obesity
0.000 0.954 0.046
J45.1 Nonallergic asthma
0.000 0.955 0.045
D80 Immunodeficiency with predominantly antibody defects
0.000 0.955 0.045
D86.1 Sarcoidosis of lymph nodes
0.000 0.955 0.045
D86.3 Sarcoidosis of skin
0.000 0.957 0.043
E11.2 With renal complications
0.042 0.957 0.001
J45.8 Mixed asthma
0.000 0.958 0.042
D84 Other immunodeficiencies
0.000 0.959 0.041
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.959 0.041
E11.1 With ketoacidosis
0.039 0.960 0.001
E11.8 With unspecified complications
0.039 0.960 0.001
H43.0 Vitreous prolapse
0.039 0.960 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.961 0.039
D82 Immunodeficiency associated with other major defects
0.000 0.963 0.037
D81 Combined immunodeficiencies
0.000 0.963 0.037
D83 Common variable immunodeficiency
0.000 0.963 0.037
E66.0 Obesity due to excess calories
0.000 0.964 0.036
H43.9 Disorder of vitreous body, unspecified
0.036 0.964 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.965 0.035
D66 Hereditary factor VIII deficiency
0.000 0.965 0.034
D73 Diseases of spleen
0.000 0.966 0.034
D84.9 Immunodeficiency, unspecified
0.000 0.966 0.033
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.967 0.033
E66.1 Drug-induced obesity
0.000 0.967 0.033
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.967 0.033
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.967 0.033
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.967 0.033
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.967 0.033
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.967 0.033
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.967 0.033
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.967 0.033
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.967 0.033
E14.3 With ophthalmic complications
0.031 0.968 0.001
D73.0 Hyposplenism
0.000 0.968 0.032
H43.2 Crystalline deposits in vitreous body
0.031 0.968 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.969 0.031
D73.5 Infarction of spleen
0.000 0.970 0.030
D84.8 Other specified immunodeficiencies
0.000 0.970 0.030
D84.1 Defects in the complement system
0.000 0.970 0.030
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.970 0.030
D55-D59 Haemolytic anaemias
0.000 0.971 0.029
D86.8 Sarcoidosis of other and combined sites
0.000 0.971 0.029
E16.2 Hypoglycaemia, unspecified
0.000 0.972 0.028
D81.9 Combined immunodeficiency, unspecified
0.000 0.973 0.027
D81.8 Other combined immunodeficiencies
0.000 0.973 0.027
D81.7 Major histocompatibility complex class II deficiency
0.000 0.973 0.027
D81.6 Major histocompatibility complex class I deficiency
0.000 0.973 0.027
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.973 0.027
D81.4 Nezelof's syndrome
0.000 0.973 0.027
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.973 0.027
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.973 0.027
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.973 0.027
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.973 0.027
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.973 0.027
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.973 0.027
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.973 0.027
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.973 0.027
D82.2 Immunodeficiency with short-limbed stature
0.000 0.973 0.027
D82.1 Di George's syndrome
0.000 0.973 0.027
D82.0 Wiskott-Aldrich syndrome
0.000 0.973 0.027
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.973 0.027
D83.8 Other common variable immunodeficiencies
0.000 0.973 0.026
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.973 0.026
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.973 0.026
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.973 0.026
D72 Other disorders of white blood cells
0.000 0.974 0.026
D83.9 Common variable immunodeficiency, unspecified
0.000 0.974 0.026
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.974 0.026
D74 Methaemoglobinaemia
0.000 0.975 0.025
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.975 0.025
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.975 0.025
D73.8 Other diseases of spleen
0.000 0.975 0.025
D73.1 Hypersplenism
0.000 0.975 0.025
D73.9 Disease of spleen, unspecified
0.000 0.976 0.024
D73.2 Chronic congestive splenomegaly
0.000 0.976 0.024
D73.3 Abscess of spleen
0.000 0.977 0.023
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.977 0.022
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.978 0.022
D89.3 Immune reconstitution syndrome
0.000 0.978 0.022
D89.1 Cryoglobulinaemia
0.000 0.978 0.022
D59 Acquired haemolytic anaemia
0.000 0.978 0.022
D73.4 Cyst of spleen
0.000 0.978 0.021
D56 Thalassaemia
0.000 0.978 0.021
D72.1 Eosinophilia
0.000 0.979 0.021
D57 Sickle-cell disorders
0.000 0.979 0.021
D55 Anaemia due to enzyme disorders
0.000 0.979 0.021
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.979 0.021
D76.3 Other histiocytosis syndromes
0.000 0.979 0.021
D50-D53 Nutritional anaemias
0.000 0.979 0.021
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.981 0.019
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.981 0.019
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.981 0.019
D72.9 Disorder of white blood cells, unspecified
0.000 0.981 0.019
D72.0 Genetic anomalies of leukocytes
0.000 0.981 0.019
Q61 Cystic kidney disease
0.019 0.981 0.000
Q38.7 Pharyngeal pouch
0.019 0.981 0.000
Q61.0 Congenital single renal cyst
0.019 0.981 0.000
D74.9 Methaemoglobinaemia, unspecified
0.000 0.982 0.018
D74.8 Other methaemoglobinaemias
0.000 0.982 0.018
D74.0 Congenital methaemoglobinaemia
0.000 0.982 0.018
H43-H45 Disorders of vitreous body and globe
0.018 0.982 0.000
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
Q61.2 Polycystic kidney, adult type
0.018 0.982 0.000
Q61.3 Polycystic kidney, unspecified
0.018 0.982 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.982 0.018
D59.1 Other autoimmune haemolytic anaemias
0.000 0.983 0.017
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.017 0.983 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.983 0.017
D53 Other nutritional anaemias
0.000 0.983 0.016
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.984 0.016
D59.8 Other acquired haemolytic anaemias
0.000 0.984 0.016
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.984 0.016
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.984 0.016
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.984 0.016
D59.3 Haemolytic-uraemic syndrome
0.000 0.984 0.016
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.984 0.016
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.984 0.016
D56.3 Thalassaemia trait
0.000 0.984 0.016
D56.9 Thalassaemia, unspecified
0.000 0.984 0.015
D56.8 Other thalassaemias
0.000 0.984 0.015
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.984 0.015
D56.2 Delta-beta thalassaemia
0.000 0.984 0.015
D56.1 Beta thalassaemia
0.000 0.984 0.015
D56.0 Alpha thalassaemia
0.000 0.984 0.015
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.985 0.015
D55.8 Other anaemias due to enzyme disorders
0.000 0.985 0.015
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.985 0.015
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.985 0.015
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.985 0.015
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.985 0.015
D57.8 Other sickle-cell disorders
0.000 0.985 0.015
D57.3 Sickle-cell trait
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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