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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs805292
log Bayes Factor = 24.5388
Chromosome 6   position 31,690,009  (GRCh37) Explore rs805292 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.4 With neurological complications
0.994 0.006 0.000
E10.3 With ophthalmic complications
0.992 0.008 0.000
J45.9 Asthma, unspecified
0.000 0.064 0.936
E10.1 With ketoacidosis
0.925 0.075 0.000
E10.2 With renal complications
0.923 0.077 0.000
E10.5 With peripheral circulatory complications
0.888 0.112 0.000
E10.0 With coma
0.884 0.116 0.000
E10-E14 Diabetes mellitus
0.752 0.248 0.000
E10.6 With other specified complications
0.720 0.280 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E11 Non-insulin-dependent diabetes mellitus
0.680 0.320 0.000
K50 Crohn's disease [regional enteritis]
0.673 0.327 0.000
K50.1 Crohn's disease of large intestine
0.658 0.342 0.000
E11.4 With neurological complications
0.655 0.345 0.000
E10.8 With unspecified complications
0.655 0.345 0.000
K50.9 Crohn's disease, unspecified
0.653 0.347 0.000
K50-K52 Noninfective enteritis and colitis
0.647 0.353 0.000
E11.0 With coma
0.627 0.373 0.000
D69.6 Thrombocytopenia, unspecified
0.000 0.377 0.623
E13 Other specified diabetes mellitus
0.619 0.381 0.000
K51 Ulcerative colitis
0.617 0.383 0.000
K52 Other non-infective gastro-enteritis and colitis
0.615 0.385 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.594 0.406 0.000
K50.0 Crohn's disease of small intestine
0.591 0.409 0.000
K50.8 Other Crohn's disease
0.584 0.416 0.000
E11.6 With other specified complications
0.579 0.421 0.000
K51.9 Ulcerative colitis, unspecified
0.576 0.424 0.000
E11.5 With peripheral circulatory complications
0.568 0.432 0.000
D69 Purpura and other haemorrhagic conditions
0.000 0.436 0.564
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.460 0.540
E12 Malnutrition-related diabetes mellitus
0.539 0.461 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.527 0.473 0.000
E13.9 Without complications
0.523 0.477 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.518 0.482 0.000
K51.2 Ulcerative (chronic) proctitis
0.517 0.483 0.000
L43.9 Lichen planus, unspecified
0.516 0.484 0.000
E14 Unspecified diabetes mellitus
0.511 0.489 0.000
K52.3 Indeterminate colitis
0.508 0.492 0.000
L43 Lichen planus
0.502 0.498 0.000
L40.5 Arthropathic psoriasis
0.497 0.503 0.000
L40 Psoriasis
0.496 0.504 0.000
L40-L45 Papulosquamous disorders
0.492 0.508 0.000
E11.7 With multiple complications
0.487 0.512 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.525 0.475
K51.4 Pseudopolyposis of colon
0.469 0.531 0.000
J45 Asthma
0.000 0.536 0.464
K51.0 Ulcerative (chronic) enterocolitis
0.460 0.540 0.000
E11.1 With ketoacidosis
0.456 0.544 0.000
K52.1 Toxic gastro-enteritis and colitis
0.454 0.546 0.000
D69.0 Allergic purpura
0.000 0.547 0.453
E13.8 With unspecified complications
0.443 0.556 0.000
E13.7 With multiple complications
0.443 0.556 0.000
E13.6 With other specified complications
0.443 0.556 0.000
E13.5 With peripheral circulatory complications
0.443 0.556 0.000
E13.4 With neurological complications
0.443 0.556 0.000
E13.3 With ophthalmic complications
0.443 0.556 0.000
E13.2 With renal complications
0.443 0.556 0.000
E13.1 With ketoacidosis
0.443 0.556 0.000
E13.0 With coma
0.443 0.556 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.441 0.559 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.440 0.560 0.000
E11.2 With renal complications
0.436 0.564 0.000
D69.4 Other primary thrombocytopenia
0.000 0.568 0.432
E14.8 With unspecified complications
0.431 0.569 0.000
K51.5 Mucosal proctocolitis
0.430 0.570 0.000
D69.5 Secondary thrombocytopenia
0.000 0.576 0.424
E14.6 With other specified complications
0.413 0.587 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.596 0.404
D69.2 Other nonthrombocytopenic purpura
0.000 0.596 0.404
E14.4 With neurological complications
0.396 0.604 0.000
L40.9 Psoriasis, unspecified
0.396 0.604 0.000
L40.1 Generalised pustular psoriasis
0.393 0.607 0.000
D69.9 Haemorrhagic condition, unspecified
0.000 0.611 0.389
E12.9 Without complications
0.386 0.613 0.000
E12.8 With unspecified complications
0.386 0.613 0.000
E12.7 With multiple complications
0.386 0.613 0.000
E12.6 With other specified complications
0.386 0.613 0.000
E12.5 With peripheral circulatory complications
0.386 0.613 0.000
E12.4 With neurological complications
0.386 0.613 0.000
E12.3 With ophthalmic complications
0.386 0.613 0.000
E12.2 With renal complications
0.386 0.613 0.000
E12.1 With ketoacidosis
0.386 0.613 0.000
E12.0 With coma
0.386 0.613 0.000
L40.8 Other psoriasis
0.386 0.614 0.000
J45.0 Predominantly allergic asthma
0.000 0.615 0.385
E14.2 Withrenal complications
0.375 0.625 0.000
E14.5 With peripheral circulatory complications
0.375 0.625 0.000
E14.1 With ketoacidosis
0.374 0.626 0.000
L42 Pityriasis rosea
0.370 0.630 0.000
E11.8 With unspecified complications
0.368 0.632 0.000
E14.7 With multiple complications
0.366 0.633 0.000
E14.0 With coma
0.366 0.633 0.000
L43.3 Subacute (active) lichen planus
0.360 0.640 0.000
L43.2 Lichenoid drug reaction
0.360 0.640 0.000
L43.1 Bullous lichen planus
0.360 0.640 0.000
L43.0 Hypertrophic lichen planus
0.360 0.640 0.000
L43.8 Other lichen planus
0.358 0.642 0.000
L40.4 Guttate psoriasis
0.355 0.645 0.000
L40.3 Pustulosis palmaris et plantaris
0.355 0.645 0.000
L40.2 Acrodermatitis continua
0.355 0.645 0.000
L44 Other papulosquamous disorders
0.353 0.647 0.000
L41 Parapsoriasis
0.353 0.647 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.353 0.647 0.000
D69.1 Qualitative platelet defects
0.000 0.655 0.344
J45.1 Nonallergic asthma
0.000 0.667 0.332
K90 Intestinal malabsorption
0.000 0.671 0.329
J45.8 Mixed asthma
0.000 0.697 0.302
L40.0 Psoriasis vulgaris
0.296 0.703 0.000
E14.3 With ophthalmic complications
0.286 0.714 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.730 0.270
E03 Other hypothyroidism
0.001 0.738 0.261
L41.9 Parapsoriasis, unspecified
0.253 0.747 0.000
L41.8 Other parapsoriasis
0.253 0.747 0.000
L41.5 Retiform parapsoriasis
0.253 0.747 0.000
L41.4 Large plaque parapsoriasis
0.253 0.747 0.000
L41.3 Small plaque parapsoriasis
0.253 0.747 0.000
L41.2 Lymphomatoid papulosis
0.253 0.747 0.000
L41.1 Pityriasis lichenoides chronica
0.253 0.747 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.253 0.747 0.000
L44.9 Papulosquamous disorder, unspecified
0.253 0.747 0.000
L44.8 Other specified papulosquamous disorders
0.253 0.747 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.253 0.747 0.000
L44.3 Lichen ruber moniliformis
0.253 0.747 0.000
L44.2 Lichen striatus
0.253 0.747 0.000
L44.1 Lichen nitidus
0.253 0.747 0.000
L44.0 Pityriasis rubra pilaris
0.253 0.747 0.000
K51.8 Other ulcerative colitis
0.244 0.755 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.764 0.236
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.764 0.236
K90.1 Tropical sprue
0.000 0.764 0.236
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.786 0.213
K90.8 Other intestinal malabsorption
0.000 0.797 0.203
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.805 0.195
E03.8 Other specified hypothyroidism
0.001 0.812 0.187
E03.5 Myxoedema coma
0.001 0.812 0.187
E03.4 Atrophy of thyroid (acquired)
0.001 0.812 0.187
E03.3 Postinfectious hypothyroidism
0.001 0.812 0.187
E03.1 Congenital hypothyroidism without goitre
0.001 0.812 0.187
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.812 0.187
K90.9 Intestinal malabsorption, unspecified
0.000 0.841 0.158
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.851 0.149
D80-D89 Certain disorders involving the immune mechanism
0.000 0.853 0.147
D86 Sarcoidosis
0.000 0.854 0.146
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.859 0.141
D86.9 Sarcoidosis, unspecified
0.000 0.859 0.141
D67 Hereditary factor IX deficiency
0.000 0.860 0.140
D80 Immunodeficiency with predominantly antibody defects
0.000 0.864 0.136
D86.0 Sarcoidosis of lung
0.000 0.871 0.129
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.874 0.126
E11.3 With ophthalmic complications
0.120 0.880 0.000
D84 Other immunodeficiencies
0.000 0.881 0.119
D86.3 Sarcoidosis of skin
0.000 0.885 0.115
D86.1 Sarcoidosis of lymph nodes
0.000 0.893 0.107
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.893 0.107
D83 Common variable immunodeficiency
0.000 0.893 0.107
D82 Immunodeficiency associated with other major defects
0.000 0.894 0.106
D81 Combined immunodeficiencies
0.000 0.894 0.106
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.895 0.105
D66 Hereditary factor VIII deficiency
0.000 0.898 0.101
D84.9 Immunodeficiency, unspecified
0.000 0.902 0.098
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.902 0.098
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.902 0.098
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.902 0.098
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.902 0.098
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.902 0.098
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.902 0.098
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.902 0.098
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.902 0.098
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.903 0.097
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.904 0.096
D86.8 Sarcoidosis of other and combined sites
0.000 0.908 0.092
D73 Diseases of spleen
0.000 0.914 0.086
D84.8 Other specified immunodeficiencies
0.000 0.915 0.085
D84.1 Defects in the complement system
0.000 0.915 0.085
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.915 0.085
D55-D59 Haemolytic anaemias
0.000 0.917 0.083
D83.9 Common variable immunodeficiency, unspecified
0.000 0.922 0.078
D83.8 Other common variable immunodeficiencies
0.000 0.923 0.077
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.923 0.077
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.923 0.077
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.923 0.077
D81.9 Combined immunodeficiency, unspecified
0.000 0.924 0.076
D81.8 Other combined immunodeficiencies
0.000 0.924 0.076
D81.7 Major histocompatibility complex class II deficiency
0.000 0.924 0.076
D81.6 Major histocompatibility complex class I deficiency
0.000 0.924 0.076
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.924 0.076
D81.4 Nezelof's syndrome
0.000 0.924 0.076
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.924 0.076
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.924 0.076
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.924 0.076
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.924 0.076
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.924 0.076
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.924 0.076
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.924 0.076
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.924 0.076
D82.2 Immunodeficiency with short-limbed stature
0.000 0.924 0.076
D82.1 Di George's syndrome
0.000 0.924 0.076
D82.0 Wiskott-Aldrich syndrome
0.000 0.924 0.076
D73.8 Other diseases of spleen
0.000 0.928 0.072
D73.5 Infarction of spleen
0.000 0.929 0.071
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.930 0.070
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.930 0.070
D89.3 Immune reconstitution syndrome
0.000 0.930 0.070
D89.1 Cryoglobulinaemia
0.000 0.930 0.070
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.931 0.069
E14.9 Without complications
0.069 0.931 0.000
D74 Methaemoglobinaemia
0.000 0.931 0.069
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.931 0.069
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.931 0.069
D73.0 Hyposplenism
0.000 0.931 0.069
D75 Other diseases of blood and blood-forming organs
0.000 0.932 0.067
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.933 0.067
D72 Other disorders of white blood cells
0.000 0.936 0.064
D59 Acquired haemolytic anaemia
0.000 0.937 0.062
D73.9 Disease of spleen, unspecified
0.000 0.938 0.062
D73.3 Abscess of spleen
0.000 0.938 0.062
D73.2 Chronic congestive splenomegaly
0.000 0.938 0.062
D73.1 Hypersplenism
0.000 0.938 0.062
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.938 0.062
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.940 0.060
D57 Sickle-cell disorders
0.000 0.940 0.059
D55 Anaemia due to enzyme disorders
0.000 0.940 0.059
D56 Thalassaemia
0.000 0.941 0.059
D73.4 Cyst of spleen
0.000 0.942 0.058
D75.2 Essential thrombocytosis
0.000 0.947 0.053
D74.9 Methaemoglobinaemia, unspecified
0.000 0.950 0.050
D74.8 Other methaemoglobinaemias
0.000 0.950 0.050
D74.0 Congenital methaemoglobinaemia
0.000 0.950 0.050
D59.1 Other autoimmune haemolytic anaemias
0.000 0.951 0.049
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.952 0.048
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.952 0.048
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.952 0.048
D72.9 Disorder of white blood cells, unspecified
0.000 0.954 0.046
D72.0 Genetic anomalies of leukocytes
0.000 0.954 0.046
D76.3 Other histiocytosis syndromes
0.000 0.954 0.045
D59.8 Other acquired haemolytic anaemias
0.000 0.955 0.045
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.955 0.045
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.955 0.045
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.955 0.045
D59.3 Haemolytic-uraemic syndrome
0.000 0.955 0.045
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.955 0.045
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.955 0.045
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.956 0.044
D72.1 Eosinophilia
0.000 0.956 0.044
D72.8 Other specified disorders of white blood cells
0.000 0.957 0.043
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.957 0.043
D55.8 Other anaemias due to enzyme disorders
0.000 0.957 0.043
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.957 0.043
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.957 0.043
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.957 0.043
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.957 0.043
D57.8 Other sickle-cell disorders
0.000 0.957 0.043
D57.3 Sickle-cell trait
0.000 0.957 0.043
D57.2 Double heterozygous sickling disorders
0.000 0.957 0.043
D57.1 Sickle-cell anaemia without crisis
0.000 0.957 0.043
D57.0 Sickle-cell anaemia with crisis
0.000 0.957 0.043
D56.9 Thalassaemia, unspecified
0.000 0.957 0.042
D56.8 Other thalassaemias
0.000 0.957 0.042
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.957 0.042
D56.2 Delta-beta thalassaemia
0.000 0.957 0.042
D56.1 Beta thalassaemia
0.000 0.957 0.042
D56.0 Alpha thalassaemia
0.000 0.957 0.042
D56.3 Thalassaemia trait
0.000 0.958 0.042
D60-D64 Aplastic and other anaemias
0.000 0.960 0.040
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.960 0.039
D75.0 Familial erythrocytosis
0.000 0.961 0.039
D58 Other hereditary haemolytic anaemias
0.001 0.964 0.035
D50-D53 Nutritional anaemias
0.000 0.964 0.036
D75.1 Secondary polycythaemia
0.000 0.964 0.036
D70 Agranulocytosis
0.000 0.965 0.035
G35 Multiple sclerosis
0.000 0.966 0.034
D62 Acute posthaemorrhagic anaemia
0.000 0.971 0.029
E00-E07 Disorders of thyroid gland
0.005 0.971 0.024
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.971 0.029
D53 Other nutritional anaemias
0.000 0.973 0.027
D58.8 Other specified hereditary haemolytic anaemias
0.001 0.974 0.026
D58.1 Hereditary elliptocytosis
0.001 0.974 0.026
D58.2 Other haemoglobinopathies
0.001 0.975 0.024
T78.4 Allergy, unspecified
0.022 0.978 0.000
D52 Folate deficiency anaemia
0.000 0.978 0.022
T78 Adverse effects, not elsewhere classified
0.021 0.979 0.000
N21.0 Calculus in bladder
0.021 0.979 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.004 0.979 0.017
E00 Congenital iodine-deficiency syndrome
0.004 0.979 0.017
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.979 0.021
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.979 0.021
D60.8 Other acquired pure red cell aplasias
0.000 0.979 0.021
D60.1 Transient acquired pure red cell aplasia
0.000 0.979 0.021
D60.0 Chronic acquired pure red cell aplasia
0.000 0.979 0.021
D53.9 Nutritional anaemia, unspecified
0.000 0.979 0.021
E02 Subclinical iodine-deficiency hypothyroidism
0.004 0.979 0.017
T78.3 Angioneurotic oedema
0.020 0.980 0.000
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
T78.0 Anaphylactic shock due to adverse food reaction
0.020 0.980 0.000
D53.8 Other specified nutritional anaemias
0.000 0.980 0.020
D53.2 Scorbutic anaemia
0.000 0.980 0.020
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.980 0.020
D53.0 Protein deficiency anaemia
0.000 0.980 0.020
D58.9 Hereditary haemolytic anaemia, unspecified
0.001 0.981 0.018
D58.0 Hereditary spherocytosis
0.001 0.981 0.018
D64 Other anaemias
0.000 0.982 0.018
Q61.0 Congenital single renal cyst
0.018 0.982 0.000
Q61 Cystic kidney disease
0.018 0.982 0.000
E07 Other disorders of thyroid
0.005 0.982 0.012
Q61.2 Polycystic kidney, adult type
0.017 0.983 0.000
T78.8 Other adverse effects, not elsewhere classified
0.016 0.983 0.000
D61 Other aplastic anaemias
0.000 0.984 0.016
Q61.3 Polycystic kidney, unspecified
0.016 0.984 0.000
D52.8 Other folate deficiency anaemias
0.000 0.984 0.016
D52.1 Drug-induced folate deficiency anaemia
0.000 0.984 0.016
D52.0 Dietary folate deficiency anaemia
0.000 0.984 0.016
T78.9 Adverse effect, unspecified
0.016 0.984 0.000
E04 Other non-toxic goitre
0.001 0.984 0.015
G61.0 Guillain-Barre syndrome
0.015 0.985 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.015 0.985 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.985 0.015
E05 Thyrotoxicosis [hyperthyroidism]
0.001 0.985 0.014
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.003 0.985 0.012
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.003 0.985 0.012
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.003 0.985 0.012
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.003 0.985 0.012
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.003 0.985 0.012
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.003 0.985 0.012
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.003 0.985 0.012
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.003 0.985 0.012
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.985 0.015
T78.2 Anaphylactic shock, unspecified
0.015 0.985 0.000
D63.0 Anaemia in neoplastic disease
0.000 0.985 0.015
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.985 0.014
G63.2 Diabetic polyneuropathy
0.015 0.985 0.000
N21 Calculus of lower urinary tract
0.015 0.985 0.000
D64.8 Other specified anaemias
0.000 0.986 0.014
Q61.4 Renal dysplasia
0.014 0.986 0.000
E06 Thyroiditis
0.005 0.986 0.009
Q61.5 Medullary cystic kidney
0.014 0.986 0.000
D64.4 Congenital dyserythropoietic anaemia
0.000 0.986 0.013
D64.3 Other sideroblastic anaemias
0.000 0.986 0.013
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.986 0.013
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.986 0.013
D64.0 Hereditary sideroblastic anaemia
0.000 0.986 0.013
G61 Inflammatory polyneuropathy
0.013 0.987 0.000
Q61.8 Other cystic kidney diseases
0.013 0.987 0.000
Q61.1 Polycystic kidney, infantile type
0.013 0.987 0.000
E07.1 Dyshormogenetic goitre
0.004 0.987 0.009
E07.0 Hypersecretion of calcitonin
0.004 0.987 0.009
E04.9 Non-toxic goitre, unspecified
0.000 0.987 0.013
E07.8 Other specified disorders of thyroid
0.003 0.987 0.010
E04.0 Non-toxic diffuse goitre
0.000 0.987 0.012
N21.1 Calculus in urethra
0.012 0.988 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.012 0.988 0.000
Q61.9 Cystic kidney disease, unspecified
0.012 0.988 0.000
Q38.7 Pharyngeal pouch
0.012 0.988 0.000
D61.0 Constitutional aplastic anaemia
0.000 0.988 0.012
D61.8 Other specified aplastic anaemias
0.000 0.988 0.012
D61.3 Idiopathic aplastic anaemia
0.000 0.988 0.012
D61.2 Aplastic anaemia due to other external agents
0.000 0.988 0.012
Q60-Q64 Congenital malformations of the urinary system
0.012 0.988 0.000
D52.9 Folate deficiency anaemia, unspecified
0.000 0.988 0.011
G61.9 Inflammatory polyneuropathy, unspecified
0.011 0.988 0.000
E04.8 Other specified non-toxic goitre
0.001 0.989 0.011
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.011 0.989 0.000
E05.8 Other thyrotoxicosis
0.001 0.989 0.010
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.989 0.011
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.989 0.011
D51.2 Transcobalamin II deficiency
0.000 0.989 0.011
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.989 0.011
E05.5 Thyroid crisis or storm
0.001 0.989 0.010
E05.4 Thyrotoxicosis factitia
0.001 0.989 0.010
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.001 0.989 0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.001 0.989 0.010
Q38 Other congenital malformations of tongue, mouth and pharynx
0.011 0.989 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.011
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.989 0.010
N21.9 Calculus of lower urinary tract, unspecified
0.011 0.989 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.011 0.989 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.011 0.989 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.989 0.011
Q38-Q45 Other congenital malformations of the digestive system
0.011 0.989 0.000
N21.8 Other lower urinary tract calculus
0.010 0.990 0.000
E06.4 Drug-induced thyroiditis
0.004 0.990 0.007
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.004 0.990 0.007
E06.0 Acute thyroiditis
0.004 0.990 0.007
D61.1 Drug-induced aplastic anaemia
0.000 0.990 0.010
E05.9 Thyrotoxicosis, unspecified
0.000 0.990 0.010
G61.1 Serum neuropathy
0.010 0.990 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.008 0.990 0.001
Q20-Q28 Congenital malformations of the circulatory system
0.010 0.990 0.000
E06.1 Subacute thyroiditis
0.004 0.990 0.006
G61.8 Other inflammatory polyneuropathies
0.009 0.990 0.000
Q80-Q89 Other congenital malformations
0.009 0.991 0.000
E06.5 Other chronic thyroiditis
0.004 0.991 0.005
G63.8 Polyneuropathy in other diseases classified elsewhere
0.009 0.991 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.009 0.991 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.009 0.991 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.009 0.991 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.009 0.991 0.000
G63.1 Polyneuropathy in neoplastic disease
0.009 0.991 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.009 0.991 0.000
Q40 Other congenital malformations of upper alimentary tract
0.009 0.991 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.009 0.991 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.991 0.009
J15 Bacterial pneumonia, not elsewhere classified
0.009 0.991 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.991 0.009
E06.3 Autoimmune thyroiditis
0.002 0.991 0.007
T66-T78 Other and unspecified effects of external causes
0.009 0.991 0.000
Q35-Q37 Cleft lip and cleft palate
0.008 0.991 0.000
E06.9 Thyroiditis, unspecified
0.005 0.991 0.004
J15.2 Pneumonia due to staphylococcus
0.008 0.991 0.000
Q85 Phakomatoses, not elsewhere classified
0.008 0.992 0.000
Q65 Congenital deformities of hip
0.008 0.992 0.000
Q83 Congenital malformations of breast
0.008 0.992 0.000
Q28 Other congenital malformations of circulatory system
0.008 0.992 0.000
Q38.8 Other congenital malformations of pharynx
0.008 0.992 0.000
Q38.6 Other congenital malformations of mouth
0.008 0.992 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.008 0.992 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.008 0.992 0.000
Q38.3 Other congenital malformations of tongue
0.008 0.992 0.000
Q38.2 Macroglossia
0.008 0.992 0.000
Q38.1 Ankyloglossia
0.008 0.992 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.008 0.992 0.000
S00.9 Superficial injury of head, part unspecified
0.000 0.992 0.008
S00.1 Contusion of eyelid and periocular area
0.000 0.992 0.008
Q39 Congenital malformations of oesophagus
0.008 0.992 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.992 0.008
E07.9 Disorder of thyroid, unspecified
0.007 0.992 0.001
Q27 Other congenital malformations of peripheral vascular system
0.008 0.992 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.008 0.992 0.000
G64 Other disorders of peripheral nervous system
0.008 0.992 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.008 0.992 0.000
Q45 Other congenital malformations of digestive system
0.008 0.992 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.008 0.992 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.008 0.992 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.008 0.992 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.992 0.006
S00 Superficial injury of head
0.000 0.992 0.008
Q63 Other congenital malformations of kidney
0.008 0.992 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.008 0.992 0.000
G60 Hereditary and idiopathic neuropathy
0.008 0.992 0.000
Q25 Congenital malformations of great arteries
0.008 0.992 0.000
Q40.3 Congenital malformation of stomach, unspecified
0.008 0.992 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.007 0.992 0.000
Q64 Other congenital malformations of urinary system
0.007 0.992 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.008 0.992 0.000
N20-N23 Urolithiasis
0.008 0.992 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.007 0.992 0.000
Q40.1 Congenital hiatus hernia
0.007 0.992 0.000
Q24 Other congenital malformations of heart
0.007 0.992 0.000
J15.5 Pneumonia due to Escherichia coli
0.007 0.993 0.000
N23 Unspecified renal colic
0.007 0.993 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.993 0.007
G36 Other acute disseminated demyelination
0.000 0.993 0.007
Q26 Congenital malformations of great veins
0.007 0.993 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.007 0.993 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.007 0.993 0.000
Q65.8 Other congenital deformities of hip
0.007 0.993 0.000
E40-E46 Malnutrition
0.006 0.993 0.001
Q83.1 Accessory breast
0.007 0.993 0.000
T66 Unspecified effects of radiation
0.007 0.993 0.000
J15.9 Bacterial pneumonia, unspecified
0.007 0.993 0.000
Q21 Congenital malformations of cardiac septa
0.007 0.993 0.000
Q89 Other congenital malformations, not elsewhere classified
0.007 0.993 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.007 0.993 0.000
Q84 Other congenital malformations of integument
0.007 0.993 0.000
Q81 Epidermolysis bullosa
0.007 0.993 0.000
Q80 Congenital ichthyosis
0.007 0.993 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.007 0.993 0.000
Q28.3 Other malformations of cerebral vessels
0.007 0.993 0.000
Q83.3 Accessory nipple
0.007 0.993 0.000
S00.7 Multiple superficial injuries of head
0.000 0.993 0.007
Q66 Congenital deformities of feet
0.007 0.993 0.000
Q37 Cleft palate with cleft lip
0.007 0.993 0.000
Q00-Q07 Congenital malformations of the nervous system
0.007 0.993 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.007 0.993 0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified
0.007 0.993 0.000
Q40.8 Other specified congenital malformations of upper alimentary tract
0.007 0.993 0.000
Q40.0 Congenital hypertrophic pyloric stenosis
0.007 0.993 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.000 0.993 0.007
Q23 Congenital malformations of aortic and mitral valves
0.007 0.993 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.007 0.993 0.000
Q75 Other congenital malformations of skull and face bones
0.007 0.993 0.000
Q73 Reduction defects of unspecified limb
0.007 0.993 0.000
Q72 Reduction defects of lower limb
0.007 0.993 0.000
Q71 Reduction defects of upper limb
0.007 0.993 0.000
Q70 Syndactyly
0.007 0.993 0.000
Q69 Polydactyly
0.007 0.993 0.000
Q68 Other congenital musculoskeletal deformities
0.007 0.993 0.000
Q39.9 Congenital malformation of oesophagus, unspecified
0.007 0.993 0.000
J15.8 Other bacterial pneumonia
0.007 0.993 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.007 0.993 0.000
J15.3 Pneumonia due to streptococcus, group B
0.007 0.993 0.000
Q27.3 Peripheral arteriovenous malformation
0.007 0.993 0.000
Q74 Other congenital malformations of limb(s)
0.007 0.993 0.000
S00.3 Superficial injury of nose
0.000 0.993 0.007
Q60 Renal agenesis and other reduction defects of kidney
0.006 0.993 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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