TreeWAS – Variant ID: rs8101881

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M19.94 Arthrosis, unspecified (Hand)	0.000	0.962	0.038
M81.90 Osteoporosis, unspecified (Multiple sites)	0.017	0.983	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.985	0.015
G62.0 Drug-induced polyneuropathy	0.000	0.985	0.015
G62 Other polyneuropathies	0.000	0.986	0.014
G93.4 Encephalopathy, unspecified	0.000	0.987	0.013
G62.1 Alcoholic polyneuropathy	0.000	0.988	0.012
G62.2 Polyneuropathy due to other toxic agents	0.000	0.990	0.010
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.990	0.010
Z88.2 Personal history of allergy to sulphonamides	0.009	0.991	0.000
G62.8 Other specified polyneuropathies	0.000	0.993	0.007
S62.30 Fracture of other metacarpal bone (closed)	0.007	0.993	0.000
D23.3 Skin of other and unspecified parts of face	0.007	0.993	0.000
S83.2 Tear of meniscus, current	0.000	0.994	0.006
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.994	0.006
M10.99 Gout, unspecified (Site unspecified)	0.000	0.994	0.006
M10.9 Gout, unspecified	0.000	0.994	0.006
M10.96 Gout, unspecified (Lower leg)	0.000	0.994	0.006
M10.94 Gout, unspecified (Hand)	0.000	0.994	0.005
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.995	0.005
S02.4 Fracture of malar and maxillary bones	0.000	0.995	0.005
M10.90 Gout, unspecified (Multiple sites)	0.000	0.995	0.005
H25.0 Senile incipient cataract	0.000	0.995	0.005
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.995	0.005
M10.93 Gout, unspecified (Forearm)	0.000	0.995	0.005
G63.2 Diabetic polyneuropathy	0.000	0.995	0.005
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
M81.9 Osteoporosis, unspecified	0.005	0.995	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.995	0.005
M10.92 Gout, unspecified (Upper arm)	0.000	0.995	0.005
S02 Fracture of skull and facial bones	0.000	0.995	0.005
S02.8 Fractures of other skull and facial bones	0.000	0.995	0.005
M10.98 Gout, unspecified (Other)	0.000	0.996	0.004
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M10.91 Gout, unspecified (Shoulder region)	0.000	0.996	0.004
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.996	0.004
G64 Other disorders of peripheral nervous system	0.000	0.996	0.004
S02.7 Multiple fractures involving skull and facial bones	0.000	0.996	0.004
S02.0 Fracture of vault of skull	0.000	0.996	0.004
M81.20 Osteoporosis of disuse (Multiple sites)	0.004	0.996	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.996	0.004
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.996	0.004
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.996	0.004
S02.2 Fracture of nasal bones	0.000	0.996	0.004
S22.00 Fracture of thoracic vertebra (closed)	0.004	0.996	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
S02.3 Fracture of orbital floor	0.000	0.996	0.004
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.996	0.004
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.996	0.004
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.996	0.004
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.996	0.004
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.996	0.004
G63.1 Polyneuropathy in neoplastic disease	0.000	0.996	0.004
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
H25.8 Other senile cataract	0.000	0.996	0.004
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.996	0.004
N20.1 Calculus of ureter	0.000	0.996	0.004
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.996	0.004
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.996	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.996	0.003
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.996	0.000
H25 Senile cataract	0.000	0.997	0.003
S02.30 Fracture of orbital floor (closed)	0.000	0.997	0.003
H25.1 Senile nuclear cataract	0.000	0.997	0.003
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.000	0.997	0.003
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.000	0.997	0.003
S02.01 Fracture of vault of skull (open)	0.000	0.997	0.003
V18.0 Driver injured in nontraffic accident	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.997	0.003
S83.7 Injury to multiple structures of knee	0.000	0.997	0.003
I35.1 Aortic (valve) insufficiency	0.000	0.997	0.003
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.997	0.003
Z95.3 Presence of xenogenic heart valve	0.000	0.997	0.003
G60 Hereditary and idiopathic neuropathy	0.000	0.997	0.003
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.997	0.003
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
S83.0 Dislocation of patella	0.000	0.997	0.003
G61 Inflammatory polyneuropathy	0.000	0.997	0.003
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.997	0.003
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.003
O30.0 Twin pregnancy	0.000	0.997	0.003
S02.6 Fracture of mandible	0.000	0.997	0.003
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
O20.0 Threatened abortion	0.000	0.997	0.003
S02.5 Fracture of tooth	0.000	0.997	0.003
S83.1 Dislocation of knee	0.000	0.997	0.003
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.997	0.003
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.003
M81.80 Other osteoporosis (Multiple sites)	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.003	0.997	0.000
G93 Other disorders of brain	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.000	0.997	0.003
G93.0 Cerebral cysts	0.000	0.997	0.003
S62.31 Fracture of other metacarpal bone (open)	0.002	0.997	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.997	0.002
O20 Haemorrhage in early pregnancy	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
B17.1 Acute hepatitis C	0.000	0.997	0.002
G60.3 Idiopathic progressive neuropathy	0.000	0.997	0.002
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.997	0.002
G60.1 Refsum's disease	0.000	0.997	0.002
J86.9 Pyothorax without fistula	0.000	0.997	0.003
S62.6 Fracture of other finger	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.998	0.002
G61.1 Serum neuropathy	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.998	0.002
G93.5 Compression of brain	0.000	0.998	0.002
W08.0 Home	0.002	0.998	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
G93.7 Reye's syndrome	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
M21.2 Flexion deformity	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
V23.5 Passenger injured in traffic accident	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
B18 Chronic viral hepatitis	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
R87.6 Abnormal cytological findings	0.002	0.998	0.000
B17 Other acute viral hepatitis	0.000	0.998	0.002
M10 Gout	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.998	0.002
V23.3 Person injured while boarding or alighting	0.000	0.998	0.002
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.998	0.002
V23.1 Passenger injured in nontraffic accident	0.000	0.998	0.002
V23.0 Driver injured in nontraffic accident	0.000	0.998	0.002
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
M23.8 Other internal derangements of knee	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.998	0.002
V18.9 Unspecified pedal cyclist injured in traffic accident	0.002	0.998	0.000
V18.4 Driver injured in traffic accident	0.002	0.998	0.000
V18.5 Passenger injured in traffic accident	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.998	0.000
B17.2 Acute hepatitis E	0.000	0.998	0.002
D23.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
V18.3 Person injured while boarding or alighting	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
Z98.1 Arthrodesis status	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.002	0.998	0.000
S62.5 Fracture of thumb	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
B18.8 Other chronic viral hepatitis	0.000	0.998	0.002
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.998	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.998	0.002
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.001
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
M10.4 Other secondary gout	0.000	0.998	0.001
M10.3 Gout due to impairment of renal function	0.000	0.998	0.001
M10.2 Drug-induced gout	0.000	0.998	0.001
M10.1 Lead-induced gout	0.000	0.998	0.001
M84 Disorders of continuity of bone	0.001	0.998	0.001
V18.1 Passenger injured in nontraffic accident	0.001	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
B18.9 Chronic viral hepatitis, unspecified	0.000	0.998	0.001
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.001	0.998	0.000
G93.2 Benign intracranial hypertension	0.000	0.998	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.998	0.001
A49.8 Other bacterial infections of unspecified site	0.002	0.998	0.000
J86 Pyothorax	0.000	0.998	0.002
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.998	0.001
S02.60 Fracture of mandible (closed)	0.000	0.998	0.001
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
B17.9 Acute viral hepatitis, unspecified	0.000	0.998	0.001
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.001	0.998	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.001	0.998	0.000
B19.9 Unspecified viral hepatitis without coma	0.000	0.998	0.001
S02.50 Fracture of tooth (closed)	0.000	0.998	0.001
B17.8 Other specified acute viral hepatitis	0.000	0.998	0.001
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
B19 Unspecified viral hepatitis	0.000	0.998	0.001
B15-B19 Viral hepatitis	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.001
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.998	0.002
J33.9 Nasal polyp, unspecified	0.000	0.998	0.002
J86.0 Pyothorax with fistula	0.000	0.998	0.001
O41.0 Oligohydramnios	0.000	0.998	0.001
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.999	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.999	0.001
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
M10.19 Lead-induced gout (Site unspecified)	0.000	0.999	0.001
M10.18 Lead-induced gout (Other)	0.000	0.999	0.001
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.999	0.001
M10.16 Lead-induced gout (Lower leg)	0.000	0.999	0.001
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.14 Lead-induced gout (Hand)	0.000	0.999	0.001
M10.13 Lead-induced gout (Forearm)	0.000	0.999	0.001
M10.12 Lead-induced gout (Upper arm)	0.000	0.999	0.001
M10.11 Lead-induced gout (Shoulder region)	0.000	0.999	0.001
M10.10 Lead-induced gout (Multiple sites)	0.000	0.999	0.001
M10.29 Drug-induced gout (Site unspecified)	0.000	0.999	0.001
M10.28 Drug-induced gout (Other)	0.000	0.999	0.001
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.999	0.001
M10.26 Drug-induced gout (Lower leg)	0.000	0.999	0.001
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.24 Drug-induced gout (Hand)	0.000	0.999	0.001
M10.23 Drug-induced gout (Forearm)	0.000	0.999	0.001
M10.22 Drug-induced gout (Upper arm)	0.000	0.999	0.001
M10.21 Drug-induced gout (Shoulder region)	0.000	0.999	0.001
M10.20 Drug-induced gout (Multiple sites)	0.000	0.999	0.001
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.999	0.001
M10.38 Gout due to impairment of renal function (Other)	0.000	0.999	0.001
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.999	0.001
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.999	0.001
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.999	0.001
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.999	0.001
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.999	0.001
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.999	0.001
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.999	0.001
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.999	0.001
M10.49 Other secondary gout (Site unspecified)	0.000	0.999	0.001
M10.48 Other secondary gout (Other)	0.000	0.999	0.001
M10.47 Other secondary gout (Ankle and foot)	0.000	0.999	0.001
M10.46 Other secondary gout (Lower leg)	0.000	0.999	0.001
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.44 Other secondary gout (Hand)	0.000	0.999	0.001
M10.43 Other secondary gout (Forearm)	0.000	0.999	0.001
M10.42 Other secondary gout (Upper arm)	0.000	0.999	0.001
M10.41 Other secondary gout (Shoulder region)	0.000	0.999	0.001
M10.40 Other secondary gout (Multiple sites)	0.000	0.999	0.001
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.999	0.001
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.999	0.001
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.001
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.001
M84.0 Malunion of fracture	0.000	0.999	0.001
S72.1 Pertrochanteric fracture	0.001	0.999	0.000
F00 Dementia in Alzheimer's disease	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.000	0.999	0.001
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.999	0.001
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.999	0.001
M84.2 Delayed union of fracture	0.001	0.999	0.001
R03.1 Nonspecific low blood-pressure reading	0.000	0.999	0.001
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
S02.10 Fracture of base of skull (closed)	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
B37.1 Pulmonary candidiasis	0.000	0.999	0.001
D23.4 Skin of scalp and neck	0.001	0.999	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.999	0.001
M84.8 Other disorders of continuity of bone	0.001	0.999	0.001
M80 Osteoporosis with pathological fracture	0.001	0.999	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.001	0.999	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.999	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.000	0.999	0.001
Z00.0 General medical examination	0.001	0.999	0.000
R87 Abnormal findings in specimens from female genital organs	0.001	0.999	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.999	0.001
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
Z76.3 Healthy person accompanying sick person	0.001	0.999	0.000
B15 Acute hepatitis A	0.000	0.999	0.001
F99-F99 Unspecified mental disorder	0.000	0.999	0.001
M84.09 Malunion of fracture (Site unspecified)	0.000	0.999	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.999	0.001
M84.00 Malunion of fracture (Multiple sites)	0.000	0.999	0.001
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.999	0.001
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.001
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.999	0.001
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.001
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.001
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.999	0.001
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.999	0.001
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.001
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.001
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.001
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.999	0.001
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.999	0.001
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.999	0.001
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.999	0.001
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.001
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.999	0.001
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.999	0.001
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.999	0.001
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.999	0.001
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
R63.1 Polydipsia	0.000	0.999	0.001
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.999	0.000
A69.2 Lyme disease	0.000	0.999	0.001
M85.6 Other cyst of bone	0.001	0.999	0.000
S06.2 Diffuse brain injury	0.000	0.999	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M84.08 Malunion of fracture (Other)	0.000	0.999	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
M10.0 Idiopathic gout	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
O30 Multiple gestation	0.000	0.999	0.001
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.001
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.001
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.001
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.001
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.001
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.001
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.001
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.999	0.001
M84.88 Other disorders of continuity of bone (Other)	0.001	0.999	0.001
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.999	0.001
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.999	0.001
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.999	0.001
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.999	0.001
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.999	0.001
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.999	0.001
S72.40 Fracture of lower end of femur (closed)	0.000	0.999	0.001
G30.9 Alzheimer's disease, unspecified	0.000	0.999	0.001
R23.8 Other and unspecified skin changes	0.001	0.999	0.000
R87.9 Unspecified abnormal finding	0.001	0.999	0.000
Z13.9 Special screening examination, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations