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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8106664
log Bayes Factor = 7.5182
Chromosome 19   position 10,728,030  (GRCh37) Explore rs8106664 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.050 0.950
Z86.7 Personal history of diseases of the circulatory system
0.000 0.060 0.940
I26 Pulmonary embolism
0.000 0.175 0.825
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.192 0.808
I80 Phlebitis and thrombophlebitis
0.000 0.204 0.796
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.263 0.737
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.266 0.734
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.313 0.687
I25 Chronic ischaemic heart disease
0.000 0.324 0.676
I20-I25 Ischaemic heart diseases
0.000 0.328 0.672
Chapter IX Diseases of the circulatory system
0.000 0.348 0.652
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.351 0.649
I24 Other acute ischaemic heart diseases
0.000 0.362 0.638
T36-T50 Poisoning by drugs, medicaments and biological substances
0.635 0.365 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.369 0.631
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.629 0.371 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.625 0.375 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.385 0.614
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.610 0.390 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.391 0.609
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.607 0.393 0.000
I82 Other venous embolism and thrombosis
0.000 0.406 0.594
I21 Acute myocardial infarction
0.000 0.420 0.580
T50.9 Other and unspecified drugs, medicaments and biological substances
0.579 0.421 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.423 0.577
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.575 0.425 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.565 0.435 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.436 0.564
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.554 0.446 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.547 0.453 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.473 0.527
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.473 0.527
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.525 0.475 0.000
T50.8 Diagnostic agents
0.521 0.479 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.479 0.521
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.480 0.520
I24.1 Dressler's syndrome
0.000 0.487 0.513
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.512 0.488 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.512 0.488 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.508 0.492 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.495 0.505
T43.2 Other and unspecified antidepressants
0.503 0.497 0.000
T45.0 Antiallergic and antiemetic drugs
0.502 0.498 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.502 0.498
I82.8 Embolism and thrombosis of other specified veins
0.000 0.503 0.497
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.490 0.510 0.000
I25.2 Old myocardial infarction
0.000 0.514 0.486
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.485 0.515 0.000
I25.6 Silent myocardial ischaemia
0.000 0.515 0.485
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.479 0.521 0.000
I28 Other diseases of pulmonary vessels
0.000 0.522 0.478
I89.1 Lymphangitis
0.000 0.525 0.475
T43.3 Phenothiazine antipsychotics and neuroleptics
0.474 0.526 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.472 0.528 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.535 0.465
I00-I02 Acute rheumatic fever
0.000 0.537 0.463
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.540 0.460
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.455 0.544 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.455 0.544 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.546 0.453
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.453 0.547 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.451 0.549 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.451 0.549 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.451 0.549 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.451 0.549 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.451 0.549 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.451 0.549 0.000
T44.0 Anticholinesterase agents
0.451 0.549 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.550 0.450
T50.7 Analeptics and opioid receptor antagonists
0.448 0.552 0.000
T50.5 Appetite depressants
0.448 0.552 0.000
T50.4 Drugs affecting uric acid metabolism
0.448 0.552 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.448 0.552 0.000
T50.1 Loop [high-ceiling] diuretics
0.448 0.552 0.000
T50.0 Mineralocorticoids and their antagonists
0.448 0.552 0.000
T36 Poisoning by systemic antibiotics
0.446 0.554 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.445 0.555 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.557 0.443
T40.2 Other opioids
0.443 0.557 0.000
T43.9 Psychotropic drug, unspecified
0.435 0.564 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.435 0.564 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.435 0.564 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.431 0.569 0.000
I22 Subsequent myocardial infarction
0.000 0.571 0.429
I82.1 Thrombophlebitis migrans
0.000 0.574 0.426
I23.8 Other current complications following acute myocardial infarction
0.000 0.577 0.423
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.417 0.583 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.584 0.416
T45.2 Vitamins, not elsewhere classified
0.407 0.593 0.000
T42.3 Barbiturates
0.405 0.594 0.000
T43.6 Psychostimulants with abuse potential
0.404 0.596 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.397 0.603 0.000
T45.8 Other primarily systemic and haematological agents
0.397 0.603 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.397 0.603 0.000
T45.6 Fibrinolysis-affecting drugs
0.397 0.603 0.000
T45.4 Iron and its compounds
0.397 0.603 0.000
T45.3 Enzymes, not elsewhere classified
0.397 0.603 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.391 0.609 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.390 0.610 0.000
T45.5 Anticoagulants
0.389 0.611 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.386 0.614 0.000
T40.6 Other and unspecified narcotics
0.385 0.615 0.000
I89.0 Lymphoedema, not elsewhere classified
0.000 0.619 0.381
T42.1 Iminostilbenes
0.379 0.621 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.378 0.622 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.622 0.378
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.622 0.378
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.622 0.378
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.377 0.623 0.000
T40.8 Lysergide [LSD]
0.377 0.623 0.000
T40.7 Cannabis (derivatives)
0.377 0.623 0.000
T40.5 Cocaine
0.377 0.623 0.000
T40.3 Methadone
0.377 0.623 0.000
T40.1 Heroin
0.377 0.623 0.000
T40.0 Opium
0.377 0.623 0.000
T40.4 Other synthetic narcotics
0.376 0.624 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.375 0.625 0.000
T42.4 Benzodiazepines
0.371 0.628 0.000
I82.0 Budd-Chiari syndrome
0.000 0.629 0.370
T48.5 Anti-common-cold drugs
0.368 0.632 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.367 0.633 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.367 0.633 0.000
T42.2 Succinimides and oxazolidinediones
0.367 0.633 0.000
I88 Nonspecific lymphadenitis
0.000 0.633 0.366
T46 Poisoning by agents primarily affecting the cardiovascular system
0.359 0.641 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.644 0.356
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.351 0.648 0.000
T37.5 Antiviral drugs
0.351 0.648 0.000
T37.4 Anthelminthics
0.351 0.648 0.000
T37.3 Other antiprotozoal drugs
0.351 0.648 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.351 0.648 0.000
T37.1 Antimycobacterial drugs
0.351 0.648 0.000
T37.0 Sulphonamides
0.351 0.648 0.000
T38.9 Other and unspecified hormone antagonists
0.348 0.652 0.000
T38.7 Androgens and anabolic congeners
0.348 0.652 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.348 0.652 0.000
T38.5 Other oestrogens and progestogens
0.348 0.652 0.000
T38.4 Oral contraceptives
0.348 0.652 0.000
T38.2 Antithyroid drugs
0.348 0.652 0.000
T38.0 Glucocorticoids and synthetic analogues
0.348 0.652 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.344 0.656 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.344 0.656 0.000
T48.4 Expectorants
0.344 0.656 0.000
T48.3 Antitussives
0.344 0.656 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.344 0.656 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.344 0.656 0.000
T48.0 Oxytocic drugs
0.344 0.656 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.657 0.343
I28.1 Aneurysm of pulmonary artery
0.000 0.657 0.343
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.657 0.343
T43.0 Tricyclic and tetracyclic antidepressants
0.341 0.659 0.000
T39.4 Antirheumatics, not elsewhere classified
0.339 0.661 0.000
T39.2 Pyrazolone derivatives
0.339 0.661 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.336 0.664 0.000
I02 Rheumatic chorea
0.000 0.668 0.332
I01 Rheumatic fever with heart involvement
0.000 0.668 0.332
T47.0 Histamine H(2)-receptor antagonists
0.331 0.669 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.671 0.329
I00 Rheumatic fever without mention of heart involvement
0.000 0.672 0.327
T41.5 Therapeutic gases
0.327 0.673 0.000
T41.4 Anaesthetic, unspecified
0.327 0.673 0.000
T41.3 Local anaesthetics
0.327 0.673 0.000
T41.2 Other and unspecified general anaesthetics
0.327 0.673 0.000
T41.1 Intravenous anaesthetics
0.327 0.673 0.000
T41.0 Inhaled anaesthetics
0.327 0.673 0.000
T49.9 Topical agent, unspecified
0.327 0.673 0.000
T49.8 Other topical agents
0.327 0.673 0.000
T49.7 Dental drugs, topically applied
0.327 0.673 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.327 0.673 0.000
T49.5 Ophthalmological drugs and preparations
0.327 0.673 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.327 0.673 0.000
T49.3 Emollients, demulcents and protectants
0.327 0.673 0.000
T49.2 Local astringents and local detergents
0.327 0.673 0.000
T49.1 Antipruritics
0.327 0.673 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.327 0.673 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.674 0.326
I86 Varicose veins of other sites
0.000 0.675 0.325
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.677 0.323
T36.9 Systemic antibiotic, unspecified
0.320 0.680 0.000
T36.8 Other systemic antibiotics
0.320 0.680 0.000
T36.7 Antifungal antibiotics, systemically used
0.320 0.680 0.000
T36.6 Rifamycins
0.320 0.680 0.000
T36.5 Aminoglycosides
0.320 0.680 0.000
T36.4 Tetracyclines
0.320 0.680 0.000
T36.3 Macrolides
0.320 0.680 0.000
T36.2 Chloramphenicol group
0.320 0.680 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.320 0.680 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.683 0.317
I87 Other disorders of veins
0.001 0.684 0.315
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.685 0.314
T36.0 Penicillins
0.311 0.689 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.690 0.310
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.309 0.691 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.309 0.691 0.000
T47.7 Emetics
0.309 0.691 0.000
T47.6 Antidiarrhoeal drugs
0.309 0.691 0.000
T47.5 Digestants
0.309 0.691 0.000
T47.4 Other laxatives
0.309 0.691 0.000
T47.3 Saline and osmotic laxatives
0.309 0.691 0.000
T47.2 Stimulant laxatives
0.309 0.691 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.306 0.694 0.000
T39.0 Salicylates
0.305 0.695 0.000
I60-I69 Cerebrovascular diseases
0.000 0.702 0.298
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.710 0.290
T38.1 Thyroid hormones and substitutes
0.285 0.715 0.000
I25.3 Aneurysm of heart
0.000 0.719 0.280
T42.0 Hydantoin derivatives
0.280 0.720 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.720 0.280
I87.8 Other specified disorders of veins
0.000 0.726 0.273
I83 Varicose veins of lower extremities
0.000 0.732 0.268
I86.8 Varicose veins of other specified sites
0.000 0.734 0.266
I88.8 Other nonspecific lymphadenitis
0.000 0.737 0.263
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.737 0.263
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.737 0.263
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.258 0.742 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.257 0.742 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.257 0.742 0.000
T46.7 Peripheral vasodilators
0.257 0.742 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.257 0.742 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.257 0.742 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.257 0.742 0.000
T46.1 Calcium-channel blockers
0.256 0.743 0.000
I25.4 Coronary artery aneurysm
0.001 0.744 0.255
T46.5 Other antihypertensive drugs, not elsewhere classified
0.254 0.746 0.000
I85 Oesophageal varices
0.000 0.748 0.252
T47.1 Other antacids and anti-gastric-secretion drugs
0.251 0.748 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.762 0.238
I01.8 Other acute rheumatic heart disease
0.000 0.762 0.238
I01.2 Acute rheumatic myocarditis
0.000 0.762 0.238
I01.1 Acute rheumatic endocarditis
0.000 0.762 0.238
I01.0 Acute rheumatic pericarditis
0.000 0.762 0.238
I02.9 Rheumatic chorea without heart involvement
0.000 0.762 0.238
I02.0 Rheumatic chorea with heart involvement
0.000 0.762 0.238
I86.3 Vulval varices
0.000 0.767 0.233
I86.0 Sublingual varices
0.000 0.767 0.233
I20 Angina pectoris
0.000 0.769 0.231
I60 Subarachnoid haemorrhage
0.000 0.771 0.229
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.773 0.227
I87.9 Disorder of vein, unspecified
0.001 0.773 0.226
I87.0 Postphlebitic syndrome
0.001 0.773 0.226
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.774 0.225
I63 Cerebral infarction
0.000 0.783 0.217
I67 Other cerebrovascular diseases
0.000 0.783 0.217
I86.2 Pelvic varices
0.000 0.784 0.216
I20.9 Angina pectoris, unspecified
0.000 0.795 0.205
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.799 0.201
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.800 0.200
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.801 0.199
I67.8 Other specified cerebrovascular diseases
0.000 0.811 0.189
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.813 0.187
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.814 0.186
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.822 0.178
I81 Portal vein thrombosis
0.001 0.822 0.177
I60.8 Other subarachnoid haemorrhage
0.000 0.824 0.176
I67.1 Cerebral aneurysm, nonruptured
0.000 0.825 0.175
I86.4 Gastric varices
0.000 0.827 0.173
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.827 0.173
I27 Other pulmonary heart diseases
0.000 0.830 0.170
T46.4 Angiotensin-converting-enzyme inhibitors
0.167 0.832 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.833 0.167
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.833 0.167
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.834 0.166
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.835 0.165
I88.9 Nonspecific lymphadenitis, unspecified
0.001 0.836 0.164
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.836 0.164
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.836 0.164
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.836 0.164
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.837 0.163
I63.8 Other cerebral infarction
0.000 0.837 0.163
I05-I09 Chronic rheumatic heart diseases
0.000 0.838 0.162
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.838 0.162
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.838 0.162
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.838 0.162
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.838 0.162
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.838 0.162
I85.0 Oesophageal varices with bleeding
0.000 0.840 0.160
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.840 0.160
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.840 0.160
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.844 0.156
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.844 0.156
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.844 0.156
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.844 0.156
I67.5 Moyamoya disease
0.000 0.844 0.156
I67.4 Hypertensive encephalopathy
0.000 0.844 0.156
I67.3 Progressive vascular leukoencephalopathy
0.000 0.844 0.156
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.846 0.154
I67.2 Cerebral atherosclerosis
0.000 0.851 0.149
I62 Other nontraumatic intracranial haemorrhage
0.000 0.852 0.148
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.853 0.147
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.856 0.144
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.856 0.144
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.856 0.144
I20.1 Angina pectoris with documented spasm
0.000 0.858 0.142
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.859 0.141
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.859 0.140
I86.1 Scrotal varices
0.000 0.861 0.139
I21.4 Acute subendocardial myocardial infarction
0.000 0.863 0.137
I87.1 Compression of vein
0.001 0.864 0.135
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.865 0.135
I21.9 Acute myocardial infarction, unspecified
0.000 0.865 0.135
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.866 0.134
I65.1 Occlusion and stenosis of basilar artery
0.000 0.866 0.134
I27.8 Other specified pulmonary heart diseases
0.000 0.867 0.133
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.867 0.132
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.868 0.132
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.869 0.131
I68.0 Cerebral amyloid angiopathy
0.000 0.869 0.130
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.872 0.128
I10-I15 Hypertensive diseases
0.000 0.873 0.127
I71 Aortic aneurysm and dissection
0.000 0.874 0.126
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.876 0.123
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.878 0.122
I27.1 Kyphoscoliotic heart disease
0.000 0.878 0.122
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.883 0.117
I06 Rheumatic aortic valve diseases
0.000 0.883 0.116
I65.2 Occlusion and stenosis of carotid artery
0.000 0.886 0.114
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.888 0.112
I63.9 Cerebral infarction, unspecified
0.000 0.888 0.112
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.889 0.111
T39.1 4-Aminophenol derivatives
0.109 0.891 0.000
I62.1 Nontraumatic extradural haemorrhage
0.000 0.893 0.106
I99 Other and unspecified disorders of circulatory system
0.000 0.900 0.100
I09 Other rheumatic heart diseases
0.000 0.900 0.099
I07 Rheumatic tricuspid valve diseases
0.000 0.901 0.099
I70 Atherosclerosis
0.000 0.901 0.099
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.901 0.099
I27.9 Pulmonary heart disease, unspecified
0.000 0.904 0.096
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.906 0.094
I15 Secondary hypertension
0.000 0.907 0.093
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.908 0.092
I13 Hypertensive heart and renal disease
0.000 0.909 0.091
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.909 0.091
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.909 0.091
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.909 0.091
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.909 0.091
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.915 0.085
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.916 0.084
I06.8 Other rheumatic aortic valve diseases
0.000 0.916 0.084
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.916 0.084
I06.1 Rheumatic aortic insufficiency
0.000 0.916 0.084
I06.0 Rheumatic aortic stenosis
0.000 0.916 0.084
I61 Intracerebral haemorrhage
0.000 0.917 0.083
I70.0 Atherosclerosis of aorta
0.000 0.919 0.081
I70.1 Atherosclerosis of renal artery
0.000 0.920 0.080
I15.9 Seconday hypertension, unspecified
0.000 0.926 0.074
I09.8 Other specified rheumatic heart diseases
0.000 0.928 0.071
I09.2 Chronic rheumatic pericarditis
0.000 0.928 0.071
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.928 0.071
I09.0 Rheumatic myocarditis
0.000 0.928 0.071
I07.9 Tricuspid valve disease, unspecified
0.000 0.929 0.071
I07.8 Other tricuspid valve diseases
0.000 0.929 0.071
I07.2 Tricuspid stenosis with insufficiency
0.000 0.929 0.071
I07.0 Tricuspid stenosis
0.000 0.929 0.071
I70.9 Generalised and unspecified atherosclerosis
0.000 0.929 0.071
I70.8 Atherosclerosis of other arteries
0.000 0.929 0.071
I74 Arterial embolism and thrombosis
0.000 0.930 0.070
I08 Multiple valve diseases
0.000 0.930 0.070
I05 Rheumatic mitral valve diseases
0.000 0.930 0.070
I11 Hypertensive heart disease
0.000 0.931 0.068
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.932 0.068
I15.8 Other secondary hypertension
0.000 0.933 0.067
I15.2 Hypertension secondary to endocrine disorders
0.000 0.933 0.067
I15.0 Renovascular hypertension
0.000 0.933 0.067
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.933 0.066
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.934 0.066
I79.1 Aortitis in diseases classified elsewhere
0.000 0.934 0.066
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.934 0.066
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.934 0.066
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.934 0.065
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.934 0.065
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.934 0.065
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.934 0.065
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.934 0.065
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.935 0.065
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.936 0.064
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.936 0.064
I78 Diseases of capillaries
0.000 0.936 0.064
I87.2 Venous insufficiency (chronic) (peripheral)
0.002 0.937 0.061
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.939 0.060
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.940 0.060
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.940 0.060
I15.1 Hypertension secondary to other renal disorders
0.000 0.940 0.060
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.941 0.059
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.942 0.058
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.942 0.058
I12 Hypertensive renal disease
0.000 0.943 0.057
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.943 0.057
I74.5 Embolism and thrombosis of iliac artery
0.000 0.945 0.055
I20.8 Other forms of angina pectoris
0.000 0.945 0.055
I09.9 Rheumatic heart disease, unspecified
0.000 0.945 0.054
I07.1 Tricuspid insufficiency
0.000 0.946 0.054
I61.8 Other intracerebral haemorrhage
0.000 0.947 0.053
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.948 0.052
M48.02 Spinal stenosis (Cervical region)
0.052 0.948 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.949 0.051
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.949 0.051
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.949 0.051
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.949 0.051
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.949 0.051
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.949 0.050
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.950 0.050
I05.8 Other mitral valve diseases
0.000 0.950 0.050
I74.8 Embolism and thrombosis of other arteries
0.000 0.950 0.050
I05.9 Mitral valve disease, unspecified
0.000 0.950 0.050
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.950 0.050
I71.0 Dissection of aorta [any part]
0.000 0.950 0.049
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.951 0.049
I27.0 Primary pulmonary hypertension
0.000 0.951 0.049
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.952 0.048
I08.9 Multiple valve disease, unspecified
0.000 0.952 0.048
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.952 0.048
I05.2 Mitral stenosis with insufficiency
0.000 0.952 0.047
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.953 0.047
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.953 0.047
I97.0 Postcardiotomy syndrome
0.000 0.953 0.047
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.953 0.047
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.953 0.047
I08.8 Other multiple valve diseases
0.000 0.953 0.047
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.953 0.047
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.953 0.047
I98.0 Cardiovascular syphilis
0.000 0.953 0.047
I78.9 Disease of capillaries, unspecified
0.000 0.954 0.046
I27.2 Other secondary pulmonary hypertension
0.000 0.954 0.046
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.955 0.045
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.958 0.042
I12.9 Hypertensive renal disease without renal failure
0.000 0.960 0.040
I97.1 Other functional disturbances following cardiac surgery
0.000 0.960 0.040
I69 Sequelae of cerebrovascular disease
0.000 0.962 0.038
I05.1 Rheumatic mitral insufficiency
0.000 0.962 0.037
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.963 0.037
M48.07 Spinal stenosis (Lumbosacral region)
0.035 0.965 0.000
I05.0 Mitral stenosis
0.000 0.966 0.034
I78.8 Other diseases of capillaries
0.000 0.966 0.034
M48.0 Spinal stenosis
0.033 0.967 0.000
I85.9 Oesophageal varices without bleeding
0.001 0.968 0.031
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.969 0.031
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.970 0.030
I77 Other disorders of arteries and arterioles
0.000 0.970 0.030
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.971 0.028
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.974 0.026
I72 Other aneurysm
0.000 0.974 0.026
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.025 0.975 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.975 0.025
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.975 0.024
I67.9 Cerebrovascular disease, unspecified
0.000 0.975 0.025
M48.05 Spinal stenosis (Thoracolumbar region)
0.024 0.976 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.024 0.976 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
I78.1 Naevus, nonneoplastic
0.000 0.976 0.024
I77.2 Rupture of artery
0.000 0.976 0.023
X60-X84 Intentional self-harm
0.023 0.977 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.022 0.978 0.000
X63.0 Home
0.022 0.978 0.000
I20.0 Unstable angina
0.000 0.978 0.022
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.978 0.021
I77.5 Necrosis of artery
0.000 0.978 0.021
I77.4 Coeliac artery compression syndrome
0.000 0.978 0.021
M48.09 Spinal stenosis (Site unspecified)
0.021 0.979 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.979 0.021
I77.8 Other specified disorders of arteries and arterioles
0.000 0.979 0.021
I08.0 Disorders of both mitral and aortic valves
0.000 0.979 0.021
Z91.5 Personal history of self-harm
0.021 0.979 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.020 0.980 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.020 0.980 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.020 0.980 0.000
I69.3 Sequelae of cerebral infarction
0.000 0.980 0.020
I73 Other peripheral vascular diseases
0.000 0.980 0.020
I77.0 Arteriovenous fistula, acquired
0.000 0.980 0.020
I77.3 Arterial fibromuscular dysplasia
0.000 0.980 0.019
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.981 0.019
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.981 0.019
M48.04 Spinal stenosis (Thoracic region)
0.019 0.981 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.019 0.981 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.019 0.981 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.981 0.019
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.018 0.982 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.018 0.982 0.000
X78 Intentional self-harm by sharp object
0.018 0.982 0.000
I77.6 Arteritis, unspecified
0.000 0.983 0.017
X68 Intentional self-poisoning by and exposure to pesticides
0.017 0.983 0.000
I72.8 Aneurysm of other specified arteries
0.000 0.983 0.017
X60.2 School, other institution and public administrative area
0.017 0.983 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.983 0.017
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.983 0.017
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.017 0.983 0.000
I72.2 Aneurysm of renal artery
0.000 0.983 0.017
X67.9 Unspecified place
0.017 0.983 0.000
X60.8 Other specified place
0.017 0.983 0.000
I72.1 Aneurysm of artery of upper extremity
0.000 0.983 0.016
X84 Intentional self-harm by unspecified means
0.017 0.983 0.000
X83 Intentional self-harm by other specified means
0.017 0.983 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.017 0.983 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.017 0.983 0.000
X80 Intentional self-harm by jumping from a high place
0.017 0.983 0.000
X79 Intentional self-harm by blunt object
0.017 0.983 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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