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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs817362
log Bayes Factor = 8.10658
Chromosome 20   position 62,559,964  (GRCh37) Explore rs817362 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I30-I52 Other forms of heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I35 Nonrheumatic aortic valve disorders
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
I35.1 Aortic (valve) insufficiency
0.000 0.009 0.991
I25.1 Atherosclerotic heart disease
0.000 0.009 0.991
I35.0 Aortic (valve) stenosis
0.000 0.013 0.987
I25.2 Old myocardial infarction
0.000 0.019 0.981
I47 Paroxysmal tachycardia
0.000 0.022 0.978
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.028 0.972
I51 Complications and ill-defined descriptions of heart disease
0.000 0.030 0.970
I22 Subsequent myocardial infarction
0.000 0.036 0.964
I45 Other conduction disorders
0.000 0.037 0.963
I47.2 Ventricular tachycardia
0.000 0.046 0.954
I51.8 Other ill-defined heart diseases
0.000 0.050 0.950
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.059 0.941
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.059 0.941
I45.1 Other and unspecified right bundle-branch block
0.000 0.075 0.925
I95 Hypotension
0.000 0.079 0.921
I50 Heart failure
0.000 0.107 0.893
I47.1 Supraventricular tachycardia
0.000 0.109 0.891
I45.6 Preexcitation syndrome
0.000 0.113 0.887
I37 Pulmonary valve disorders
0.000 0.113 0.887
I10-I15 Hypertensive diseases
0.000 0.115 0.885
I95.1 Orthostatic hypotension
0.000 0.115 0.885
I26 Pulmonary embolism
0.000 0.128 0.872
I99 Other and unspecified disorders of circulatory system
0.000 0.137 0.863
I10 Essential (primary) hypertension
0.000 0.141 0.859
I50.1 Left ventricular failure
0.000 0.141 0.859
I51.9 Heart disease, unspecified
0.000 0.148 0.852
I25.3 Aneurysm of heart
0.000 0.150 0.850
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.165 0.835
I25.4 Coronary artery aneurysm
0.000 0.168 0.832
I35.9 Aortic valve disorder, unspecified
0.000 0.174 0.826
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.177 0.823
I20 Angina pectoris
0.000 0.179 0.821
I42 Cardiomyopathy
0.000 0.191 0.809
I37.1 Pulmonary valve insufficiency
0.000 0.194 0.806
I20.8 Other forms of angina pectoris
0.000 0.214 0.786
I27 Other pulmonary heart diseases
0.000 0.219 0.781
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.223 0.777
I38 Endocarditis, valve unspecified
0.000 0.224 0.776
I51.6 Cardiovascular disease, unspecified
0.000 0.233 0.767
I25.5 Ischaemic cardiomyopathy
0.000 0.237 0.763
I51.4 Myocarditis, unspecified
0.000 0.250 0.749
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.260 0.740
I45.2 Bifascicular block
0.000 0.268 0.732
I24 Other acute ischaemic heart diseases
0.000 0.275 0.725
I36 Nonrheumatic tricuspid valve disorders
0.000 0.275 0.725
I95.9 Hypotension, unspecified
0.000 0.279 0.721
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I52 Other heart disorders in diseases classified elsewhere
0.000 0.283 0.717
I48 Atrial fibrillation and flutter
0.000 0.283 0.717
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.283 0.717
I41 Myocarditis in diseases classified elsewhere
0.000 0.283 0.717
I40 Acute myocarditis
0.000 0.283 0.717
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.283 0.717
I32 Pericarditis in diseases classified elsewhere
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.286 0.713
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.296 0.704
I50.0 Congestive heart failure
0.000 0.298 0.702
I42.2 Other hypertrophic cardiomyopathy
0.000 0.304 0.696
I51.5 Myocardial degeneration
0.000 0.305 0.695
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.305 0.695
I45.0 Right fascicular block
0.000 0.309 0.690
I47.0 Reentry ventricular arrhythmia
0.000 0.310 0.690
I27.9 Pulmonary heart disease, unspecified
0.000 0.319 0.681
I45.3 Trifascicular block
0.000 0.320 0.680
I45.8 Other specified conduction disorders
0.000 0.320 0.680
I22.8 Subsequent myocardial infarction of other sites
0.000 0.322 0.678
I28 Other diseases of pulmonary vessels
0.000 0.325 0.675
I42.6 Alcoholic cardiomyopathy
0.000 0.327 0.673
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.329 0.670
I23 Certain current complications following acute myocardial infarction
0.000 0.337 0.663
I95.0 Idiopathic hypotension
0.000 0.339 0.660
I20.9 Angina pectoris, unspecified
0.000 0.340 0.660
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.341 0.659
I95.8 Other hypotension
0.000 0.341 0.659
I77 Other disorders of arteries and arterioles
0.000 0.343 0.657
I33 Acute and subacute endocarditis
0.000 0.344 0.656
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.345 0.655
I45.9 Conduction disorder, unspecified
0.000 0.352 0.648
I27.2 Other secondary pulmonary hypertension
0.000 0.352 0.648
I97.1 Other functional disturbances following cardiac surgery
0.000 0.359 0.640
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.364 0.636
I37.9 Pulmonary valve disorder, unspecified
0.000 0.364 0.636
I37.8 Other pulmonary valve disorders
0.000 0.364 0.636
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.364 0.636
I37.0 Pulmonary valve stenosis
0.000 0.364 0.636
I13 Hypertensive heart and renal disease
0.000 0.365 0.635
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.367 0.633
I30 Acute pericarditis
0.000 0.369 0.631
I60-I69 Cerebrovascular diseases
0.000 0.373 0.627
I74 Arterial embolism and thrombosis
0.000 0.373 0.627
I45.4 Nonspecific intraventricular block
0.000 0.380 0.620
I34 Nonrheumatic mitral valve disorders
0.000 0.385 0.615
I71 Aortic aneurysm and dissection
0.000 0.385 0.615
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.393 0.607
I11 Hypertensive heart disease
0.000 0.400 0.599
I15 Secondary hypertension
0.000 0.402 0.598
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.405 0.595
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.406 0.594
I69 Sequelae of cerebrovascular disease
0.000 0.406 0.594
I21 Acute myocardial infarction
0.000 0.409 0.591
I51.0 Cardiac septal defect, acquired
0.000 0.409 0.591
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.409 0.590
I97.0 Postcardiotomy syndrome
0.000 0.409 0.590
I95.2 Hypotension due to drugs
0.000 0.414 0.585
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.420 0.580
I42.5 Other restrictive cardiomyopathy
0.000 0.420 0.580
I42.4 Endocardial fibroelastosis
0.000 0.420 0.580
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.420 0.580
I69.3 Sequelae of cerebral infarction
0.000 0.430 0.570
I78 Diseases of capillaries
0.000 0.435 0.565
I27.1 Kyphoscoliotic heart disease
0.000 0.440 0.560
I77.6 Arteritis, unspecified
0.000 0.447 0.553
I27.0 Primary pulmonary hypertension
0.000 0.451 0.549
I35.8 Other aortic valve disorders
0.000 0.456 0.544
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.463 0.537
I77.0 Arteriovenous fistula, acquired
0.000 0.464 0.536
I72 Other aneurysm
0.000 0.469 0.531
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.469 0.531
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.470 0.530
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.472 0.528
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.476 0.524
I42.8 Other cardiomyopathies
0.000 0.476 0.523
I24.1 Dressler's syndrome
0.000 0.480 0.520
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.480 0.520
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.480 0.520
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.480 0.520
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.480 0.520
I46 Cardiac arrest
0.000 0.481 0.519
I42.9 Cardiomyopathy, unspecified
0.000 0.482 0.518
I77.8 Other specified disorders of arteries and arterioles
0.000 0.483 0.517
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.486 0.514
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.486 0.514
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.486 0.514
I40.9 Acute myocarditis, unspecified
0.000 0.486 0.514
I40.8 Other acute myocarditis
0.000 0.486 0.514
I40.1 Isolated myocarditis
0.000 0.486 0.514
I40.0 Infective myocarditis
0.000 0.486 0.514
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.486 0.514
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.486 0.514
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.486 0.514
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.486 0.514
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.486 0.514
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.486 0.514
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.486 0.514
I48.4 Atypical atrial flutter
0.000 0.486 0.514
I48.3 Typical atrial flutter
0.000 0.486 0.514
I48.2 Chronic atrial fibrillation
0.000 0.486 0.514
I48.1 Persistent atrial fibrillation
0.000 0.486 0.514
I48.0 Paroxysmal atrial fibrillation
0.000 0.486 0.514
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.486 0.514
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.486 0.514
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.486 0.514
I62 Other nontraumatic intracranial haemorrhage
0.000 0.487 0.513
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.497 0.503
I42.0 Dilated cardiomyopathy
0.000 0.502 0.498
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.503 0.497
I70 Atherosclerosis
0.000 0.506 0.494
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.511 0.489
I78.1 Naevus, nonneoplastic
0.000 0.514 0.486
I73 Other peripheral vascular diseases
0.000 0.514 0.486
I63 Cerebral infarction
0.000 0.516 0.484
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.516 0.484
I28.8 Other specified diseases of pulmonary vessels
0.000 0.516 0.484
I28.1 Aneurysm of pulmonary artery
0.000 0.516 0.484
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.516 0.484
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.518 0.482
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.518 0.482
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.519 0.481
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.521 0.479
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.523 0.477
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.525 0.475
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.525 0.475
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.525 0.475
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.525 0.475
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.525 0.475
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.525 0.475
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.525 0.475
I74.8 Embolism and thrombosis of other arteries
0.000 0.525 0.475
I77.5 Necrosis of artery
0.000 0.529 0.471
I77.4 Coeliac artery compression syndrome
0.000 0.529 0.471
I77.3 Arterial fibromuscular dysplasia
0.000 0.529 0.471
I33.9 Acute endocarditis, unspecified
0.000 0.529 0.470
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.537 0.463
I05-I09 Chronic rheumatic heart diseases
0.000 0.538 0.462
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.542 0.457
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.545 0.455
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.545 0.455
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.545 0.455
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.545 0.455
I47.9 Paroxysmal tachycardia, unspecified
0.001 0.545 0.455
I30.8 Other forms of acute pericarditis
0.000 0.547 0.453
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.547 0.453
I45.5 Other specified heart block
0.000 0.548 0.452
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.550 0.450
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.551 0.449
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.551 0.449
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.551 0.449
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.556 0.444
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.559 0.441
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.559 0.441
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.559 0.441
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.559 0.441
I44 Atrioventricular and left bundle-branch block
0.000 0.561 0.438
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.563 0.436
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.568 0.432
I15.8 Other secondary hypertension
0.000 0.571 0.429
I15.2 Hypertension secondary to endocrine disorders
0.000 0.571 0.429
I15.0 Renovascular hypertension
0.000 0.571 0.429
I15.1 Hypertension secondary to other renal disorders
0.000 0.573 0.427
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.574 0.426
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.575 0.425
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.576 0.424
I23.8 Other current complications following acute myocardial infarction
0.000 0.579 0.421
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.582 0.418
I30.9 Acute pericarditis, unspecified
0.000 0.583 0.417
I67 Other cerebrovascular diseases
0.000 0.584 0.416
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.585 0.414
I30.1 Infective pericarditis
0.000 0.589 0.411
I72.8 Aneurysm of other specified arteries
0.000 0.590 0.410
I33.0 Acute and subacute infective endocarditis
0.000 0.590 0.409
I78.9 Disease of capillaries, unspecified
0.000 0.595 0.405
I71.0 Dissection of aorta [any part]
0.000 0.596 0.404
I72.0 Aneurysm of carotid artery
0.000 0.601 0.398
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.602 0.397
I20.1 Angina pectoris with documented spasm
0.000 0.605 0.395
I15.9 Seconday hypertension, unspecified
0.000 0.605 0.395
I73.9 Peripheral vascular disease, unspecified
0.000 0.605 0.395
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.610 0.390
I74.5 Embolism and thrombosis of iliac artery
0.000 0.611 0.389
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.613 0.387
I67.9 Cerebrovascular disease, unspecified
0.000 0.613 0.387
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.613 0.386
I27.8 Other specified pulmonary heart diseases
0.001 0.616 0.383
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.617 0.383
I44.7 Left bundle-branch block, unspecified
0.000 0.618 0.382
I77.1 Stricture of artery
0.000 0.618 0.382
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.619 0.381
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.619 0.381
I72.2 Aneurysm of renal artery
0.000 0.619 0.381
I72.1 Aneurysm of artery of upper extremity
0.000 0.619 0.381
I77.2 Rupture of artery
0.000 0.620 0.380
I44.2 Atrioventricular block, complete
0.000 0.621 0.379
I72.3 Aneurysm of iliac artery
0.000 0.621 0.378
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.623 0.377
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.623 0.377
I46.1 Sudden cardiac death, so described
0.000 0.627 0.372
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.631 0.369
I01.8 Other acute rheumatic heart disease
0.000 0.631 0.369
I01.2 Acute rheumatic myocarditis
0.000 0.631 0.369
I01.1 Acute rheumatic endocarditis
0.000 0.631 0.369
I01.0 Acute rheumatic pericarditis
0.000 0.631 0.369
I02.9 Rheumatic chorea without heart involvement
0.000 0.631 0.369
I02.0 Rheumatic chorea with heart involvement
0.000 0.631 0.369
I62.1 Nontraumatic extradural haemorrhage
0.000 0.632 0.368
I07 Rheumatic tricuspid valve diseases
0.000 0.632 0.368
I34.0 Mitral (valve) insufficiency
0.000 0.633 0.367
I72.9 Aneurysm of unspecified site
0.000 0.635 0.365
I70.9 Generalised and unspecified atherosclerosis
0.000 0.646 0.354
I70.8 Atherosclerosis of other arteries
0.000 0.646 0.354
I70.1 Atherosclerosis of renal artery
0.000 0.648 0.352
I46.9 Cardiac arrest, unspecified
0.000 0.649 0.351
I73.8 Other specified peripheral vascular diseases
0.000 0.651 0.348
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.651 0.348
I78.8 Other diseases of capillaries
0.000 0.652 0.347
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.653 0.347
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.653 0.347
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.653 0.347
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.653 0.347
I70.0 Atherosclerosis of aorta
0.000 0.654 0.346
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.656 0.344
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.660 0.339
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.001 0.668 0.332
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.001 0.668 0.332
I98.0 Cardiovascular syphilis
0.001 0.668 0.332
I06 Rheumatic aortic valve diseases
0.000 0.669 0.331
I31 Other diseases of pericardium
0.000 0.669 0.331
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.672 0.328
I79.1 Aortitis in diseases classified elsewhere
0.000 0.672 0.328
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.672 0.328
I09 Other rheumatic heart diseases
0.000 0.675 0.325
I60 Subarachnoid haemorrhage
0.000 0.676 0.324
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.677 0.322
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.677 0.322
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.677 0.322
I68.0 Cerebral amyloid angiopathy
0.000 0.677 0.322
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.682 0.318
I44.5 Left posterior fascicular block
0.000 0.685 0.314
I44.4 Left anterior fascicular block
0.000 0.685 0.314
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.688 0.312
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.691 0.309
I72.4 Aneurysm of artery of lower extremity
0.000 0.692 0.308
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.695 0.305
I07.1 Tricuspid insufficiency
0.000 0.700 0.300
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.701 0.298
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.701 0.298
I67.5 Moyamoya disease
0.000 0.701 0.298
I67.4 Hypertensive encephalopathy
0.000 0.701 0.298
I67.3 Progressive vascular leukoencephalopathy
0.000 0.701 0.298
I34.1 Mitral (valve) prolapse
0.000 0.703 0.297
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.703 0.297
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.703 0.297
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.703 0.297
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.703 0.297
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.703 0.297
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.703 0.297
I67.2 Cerebral atherosclerosis
0.000 0.706 0.293
I49 Other cardiac arrhythmias
0.000 0.707 0.293
I12 Hypertensive renal disease
0.000 0.721 0.279
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.725 0.274
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.725 0.274
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.725 0.274
I65.1 Occlusion and stenosis of basilar artery
0.000 0.725 0.274
I63.8 Other cerebral infarction
0.000 0.731 0.269
I07.9 Tricuspid valve disease, unspecified
0.000 0.736 0.264
I07.8 Other tricuspid valve diseases
0.000 0.736 0.264
I07.2 Tricuspid stenosis with insufficiency
0.000 0.736 0.264
I07.0 Tricuspid stenosis
0.000 0.736 0.264
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.738 0.262
I44.6 Other and unspecified fascicular block
0.000 0.741 0.258
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.743 0.256
I65.2 Occlusion and stenosis of carotid artery
0.000 0.743 0.257
I49.3 Ventricular premature depolarisation
0.000 0.745 0.255
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.746 0.254
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.746 0.254
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.746 0.254
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.746 0.254
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.748 0.252
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.750 0.250
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.752 0.248
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.754 0.246
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.760 0.240
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.762 0.238
I06.8 Other rheumatic aortic valve diseases
0.000 0.762 0.238
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.762 0.238
I06.1 Rheumatic aortic insufficiency
0.000 0.762 0.238
I06.0 Rheumatic aortic stenosis
0.000 0.762 0.238
I31.8 Other specified diseases of pericardium
0.000 0.762 0.237
I31.2 Haemopericardium, not elsewhere classified
0.000 0.762 0.237
I31.0 Chronic adhesive pericarditis
0.000 0.762 0.237
I09.8 Other specified rheumatic heart diseases
0.000 0.767 0.233
I09.2 Chronic rheumatic pericarditis
0.000 0.767 0.233
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.767 0.233
I09.0 Rheumatic myocarditis
0.000 0.767 0.233
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.767 0.233
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.767 0.233
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.767 0.233
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.767 0.233
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.767 0.232
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.768 0.232
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.771 0.228
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.772 0.228
I09.9 Rheumatic heart disease, unspecified
0.000 0.773 0.227
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.774 0.226
I69.0 Sequelae of subarachnoid haemorrhage
0.001 0.775 0.224
I63.9 Cerebral infarction, unspecified
0.000 0.775 0.225
I44.3 Other and unspecified atrioventricular block
0.000 0.777 0.223
I46.0 Cardiac arrest with successful resuscitation
0.000 0.781 0.218
I49.4 Other and unspecified premature depolarisation
0.000 0.782 0.218
I21.4 Acute subendocardial myocardial infarction
0.000 0.782 0.218
I44.1 Atrioventricular block, second degree
0.000 0.783 0.217
I08 Multiple valve diseases
0.000 0.785 0.215
I49.2 Junctional premature depolarisation
0.000 0.789 0.210
I67.8 Other specified cerebrovascular diseases
0.000 0.790 0.210
I31.1 Chronic constrictive pericarditis
0.000 0.790 0.209
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.791 0.209
I60.8 Other subarachnoid haemorrhage
0.000 0.792 0.208
I67.1 Cerebral aneurysm, nonruptured
0.000 0.796 0.203
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.800 0.200
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.806 0.194
I05 Rheumatic mitral valve diseases
0.000 0.808 0.192
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.817 0.183
I31.9 Disease of pericardium, unspecified
0.000 0.818 0.182
I61 Intracerebral haemorrhage
0.001 0.825 0.174
I49.1 Atrial premature depolarisation
0.000 0.827 0.173
I73.0 Raynaud's syndrome
0.000 0.830 0.170
I49.0 Ventricular fibrillation and flutter
0.000 0.830 0.170
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.836 0.164
I24.8 Other forms of acute ischaemic heart disease
0.000 0.840 0.160
I08.9 Multiple valve disease, unspecified
0.000 0.846 0.154
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.846 0.154
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.847 0.152
I49.5 Sick sinus syndrome
0.000 0.849 0.151
I49.9 Cardiac arrhythmia, unspecified
0.000 0.853 0.147
I12.9 Hypertensive renal disease without renal failure
0.000 0.855 0.144
I20.0 Unstable angina
0.000 0.855 0.145
I50.9 Heart failure, unspecified
0.000 0.860 0.140
I05.8 Other mitral valve diseases
0.000 0.862 0.137
I51.7 Cardiomegaly
0.000 0.864 0.136
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.866 0.134
I05.0 Mitral stenosis
0.000 0.869 0.131
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.872 0.128
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.873 0.126
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.874 0.125
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.874 0.125
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.875 0.124
I08.8 Other multiple valve diseases
0.000 0.880 0.120
I05.2 Mitral stenosis with insufficiency
0.000 0.881 0.118
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.001 0.883 0.116
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.884 0.115
I05.1 Rheumatic mitral insufficiency
0.001 0.887 0.113
I08.0 Disorders of both mitral and aortic valves
0.000 0.887 0.113
I49.8 Other specified cardiac arrhythmias
0.000 0.890 0.110
I05.9 Mitral valve disease, unspecified
0.000 0.895 0.104
I31.3 Pericardial effusion (noninflammatory)
0.000 0.900 0.100
I61.8 Other intracerebral haemorrhage
0.001 0.910 0.089
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.929 0.071
J40-J47 Chronic lower respiratory diseases
0.000 0.934 0.066
J43.9 Emphysema, unspecified
0.000 0.934 0.066
J69.0 Pneumonitis due to food and vomit
0.000 0.935 0.065
J43 Emphysema
0.000 0.935 0.065
Chapter X Diseases of the respiratory system
0.000 0.936 0.064
J69 Pneumonitis due to solids and liquids
0.000 0.936 0.064
J09-J18 Influenza and pneumonia
0.000 0.936 0.064
J60-J70 Lung diseases due to external agents
0.000 0.936 0.064
J47 Bronchiectasis
0.000 0.936 0.064
J18.1 Lobar pneumonia, unspecified
0.000 0.937 0.063
J18 Pneumonia, organism unspecified
0.000 0.937 0.063
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.937 0.063
J84 Other interstitial pulmonary diseases
0.000 0.938 0.062
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.938 0.062
J45 Asthma
0.000 0.939 0.061
I82 Other venous embolism and thrombosis
0.000 0.941 0.059
J18.0 Bronchopneumonia, unspecified
0.000 0.941 0.059
J45.0 Predominantly allergic asthma
0.000 0.941 0.059
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.944 0.056
J20-J22 Other acute lower respiratory infections
0.000 0.944 0.056
I88 Nonspecific lymphadenitis
0.000 0.945 0.054
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.946 0.054
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.947 0.053
I83 Varicose veins of lower extremities
0.000 0.947 0.053
J22 Unspecified acute lower respiratory infection
0.000 0.948 0.052
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.949 0.051
J80 Adult respiratory distress syndrome
0.000 0.951 0.049
J84.8 Other specified interstitial pulmonary diseases
0.000 0.951 0.049
J43.2 Centrilobular emphysema
0.000 0.951 0.048
I81 Portal vein thrombosis
0.000 0.952 0.048
I82.2 Embolism and thrombosis of vena cava
0.000 0.952 0.048
J86 Pyothorax
0.000 0.952 0.048
J46 Status asthmaticus
0.000 0.952 0.048
J43.8 Other emphysema
0.000 0.953 0.047
J43.1 Panlobular emphysema
0.000 0.953 0.047
J43.0 MacLeod's syndrome
0.000 0.953 0.047
J69.1 Pneumonitis due to oils and essences
0.000 0.954 0.046
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.954 0.046
J12 Viral pneumonia, not elsewhere classified
0.000 0.954 0.046
J09 Influenza due to certain identified influenza virus
0.000 0.954 0.046
J70 Respiratory conditions due to other external agents
0.000 0.954 0.046
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.954 0.046
J66 Airway disease due to specific organic dust
0.000 0.954 0.046
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.954 0.046
J62 Pneumoconiosis due to dust containing silica
0.000 0.954 0.046
J65 Pneumoconiosis associated with tuberculosis
0.000 0.954 0.046
J60 Coalworker's pneumoconiosis
0.000 0.954 0.046
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.954 0.046
J18.8 Other pneumonia, organism unspecified
0.000 0.954 0.046
J18.2 Hypostatic pneumonia, unspecified
0.000 0.954 0.046
I82.8 Embolism and thrombosis of other specified veins
0.000 0.955 0.045
J69.8 Pneumonitis due to other solids and liquids
0.000 0.955 0.045
J84.0 Alveolar and parietoalveolar conditions
0.000 0.956 0.044
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.956 0.044
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.956 0.044
J45.8 Mixed asthma
0.000 0.956 0.044
J45.1 Nonallergic asthma
0.000 0.956 0.044
J81 Pulmonary oedema
0.000 0.956 0.044
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.957 0.043
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.957 0.043
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.957 0.043
J15.4 Pneumonia due to other streptococci
0.000 0.957 0.043
J17 Pneumonia in diseases classified elsewhere
0.000 0.957 0.043
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.957 0.043
I82.3 Embolism and thrombosis of renal vein
0.000 0.957 0.043
I82.1 Thrombophlebitis migrans
0.000 0.957 0.043
I82.0 Budd-Chiari syndrome
0.000 0.957 0.043
J41 Simple and mucopurulent chronic bronchitis
0.000 0.957 0.043
J64 Unspecified pneumoconiosis
0.000 0.957 0.043
J86.9 Pyothorax without fistula
0.000 0.957 0.043
E78.0 Pure hypercholesterolaemia
0.000 0.958 0.042
J11 Influenza, virus not identified
0.000 0.958 0.042
J45.9 Asthma, unspecified
0.000 0.958 0.042
I80 Phlebitis and thrombophlebitis
0.000 0.958 0.042
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.960 0.040

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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