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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8177313
log Bayes Factor = 8.14533
Chromosome 3   position 133,464,102  (GRCh37) Explore rs8177313 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
M06 Other rheumatoid arthritis
0.994 0.006 0.000
M06.9 Rheumatoid arthritis, unspecified
0.993 0.007 0.000
F10.1 Harmful use
0.990 0.010 0.000
F10.0 Acute intoxication
0.983 0.017 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.982 0.018 0.000
D00-D09 In situ neoplasms
0.981 0.019 0.000
G20-G26 Extrapyramidal and movement disorders
0.973 0.027 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.971 0.029 0.000
M80-M85 Disorders of bone density and structure
0.970 0.030 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.961 0.039 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.960 0.040 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.953 0.047 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.950 0.050 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.949 0.051 0.000
C79 Secondary malignant neoplasm of other sites
0.947 0.053 0.000
F10.2 Dependence syndrome
0.944 0.056 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.943 0.057 0.000
G20 Parkinson's disease
0.937 0.063 0.000
C77.1 Intrathoracic lymph nodes
0.932 0.068 0.000
C51-C58 Malignant neoplasms of female genital organs
0.929 0.071 0.000
G30-G32 Other degenerative diseases of the nervous system
0.928 0.072 0.000
F41 Other anxiety disorders
0.920 0.080 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.918 0.082 0.000
D45 Polycythaemia vera
0.913 0.087 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.912 0.088 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.911 0.089 0.000
G24 Dystonia
0.907 0.093 0.000
C34 Malignant neoplasm of bronchus and lung
0.902 0.098 0.000
F03 Unspecified dementia
0.900 0.100 0.000
F40 Phobic anxiety disorders
0.899 0.101 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.898 0.102 0.000
F41.9 Anxiety disorder, unspecified
0.895 0.105 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.893 0.107 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.889 0.111 0.000
C54 Malignant neoplasm of corpus uteri
0.887 0.113 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.882 0.118 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.880 0.120 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.879 0.121 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.878 0.122 0.000
F60-F69 Disorders of adult personality and behaviour
0.877 0.123 0.000
D05 Carcinoma in situ of breast
0.877 0.123 0.000
M85 Other disorders of bone density and structure
0.877 0.123 0.000
D06 Carcinoma in situ of cervix uteri
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.868 0.132 0.000
M80 Osteoporosis with pathological fracture
0.866 0.134 0.000
M05 Seropositive rheumatoid arthritis
0.862 0.138 0.000
M45-M49 Spondylopathies
0.860 0.140 0.000
G30 Alzheimer's disease
0.859 0.141 0.000
C83.3 Large cell (diffuse)
0.859 0.141 0.000
C54.1 Endometrium
0.858 0.142 0.000
F43 Reaction to severe stress, and adjustment disorders
0.856 0.144 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.853 0.147 0.000
T40.2 Other opioids
0.851 0.149 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.851 0.149 0.000
M84 Disorders of continuity of bone
0.849 0.151 0.000
C77.5 Intrapelvic lymph nodes
0.843 0.157 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.843 0.157 0.000
F40.2 Specific (isolated) phobias
0.840 0.160 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.840 0.160 0.000
M10 Gout
0.840 0.160 0.000
C34.1 Upper lobe, bronchus or lung
0.837 0.163 0.000
F10.3 Withdrawal state
0.836 0.164 0.000
S40-S49 Injuries to the shoulder and upper arm
0.835 0.165 0.000
C80 Malignant neoplasm without specification of site
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.831 0.169 0.000
S60-S69 Injuries to the wrist and hand
0.830 0.170 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.817 0.183 0.000
S10-S19 Injuries to the neck
0.816 0.184 0.000
M45 Ankylosing spondylitis
0.812 0.188 0.000
G30.9 Alzheimer's disease, unspecified
0.810 0.190 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.808 0.192 0.000
C77.3 Axillary and upper limb lymph nodes
0.805 0.195 0.000
S50-S59 Injuries to the elbow and forearm
0.804 0.196 0.000
C91 Lymphoid leukaemia
0.802 0.198 0.000
C88 Malignant immunoproliferative diseases
0.801 0.199 0.000
G70-G73 Diseases of myoneural junction and muscle
0.800 0.200 0.000
T43.2 Other and unspecified antidepressants
0.798 0.202 0.000
D04 Carcinoma in situ of skin
0.796 0.204 0.000
S20-S29 Injuries to the thorax
0.795 0.205 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.794 0.206 0.000
T92 Sequelae of injuries of upper limb
0.794 0.206 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.793 0.207 0.000
M85.8 Other specified disorders of bone density and structure
0.793 0.207 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.792 0.208 0.000
D06.9 Cervix, unspecified
0.790 0.210 0.000
M60-M63 Disorders of muscles
0.788 0.212 0.000
G93 Other disorders of brain
0.788 0.212 0.000
G24.9 Dystonia, unspecified
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
C81 Hodgkin's disease
0.784 0.216 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.784 0.216 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.782 0.218 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.782 0.218 0.000
F41.1 Generalised anxiety disorder
0.779 0.221 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.779 0.221 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.777 0.223 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.776 0.224 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.776 0.224 0.000
G24.3 Spasmodic torticollis
0.776 0.224 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.775 0.225 0.000
T36 Poisoning by systemic antibiotics
0.774 0.225 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.774 0.226 0.000
M40-M43 Deforming dorsopathies
0.773 0.227 0.000
M07 Psoriatic and enteropathic arthropathies
0.773 0.227 0.000
F60 Specific personality disorders
0.773 0.227 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.773 0.227 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.772 0.228 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.772 0.228 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.769 0.231 0.000
G40-G47 Episodic and paroxysmal disorders
0.768 0.232 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.766 0.234 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.766 0.234 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.764 0.236 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.762 0.237 0.000
T42.4 Benzodiazepines
0.761 0.239 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.761 0.239 0.000
C83.0 Small cell (diffuse)
0.761 0.239 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.760 0.239 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.758 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.757 0.243 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.752 0.248 0.000
D37.6 Liver, gallbladder and bile ducts
0.750 0.250 0.000
T31 Burns classified according to extent of body surface involved
0.749 0.251 0.000
D37.2 Small intestine
0.749 0.251 0.000
C34.9 Bronchus or lung, unspecified
0.748 0.252 0.000
C79.2 Secondary malignant neoplasm of skin
0.747 0.253 0.000
F10.9 Unspecified mental and behavioural disorder
0.747 0.253 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.747 0.253 0.000
C77.0 Lymph nodes of head, face and neck
0.746 0.254 0.000
C53 Malignant neoplasm of cervix uteri
0.745 0.255 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.743 0.257 0.000
C92 Myeloid leukaemia
0.742 0.258 0.000
F00 Dementia in Alzheimer's disease
0.741 0.258 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.740 0.260 0.000
C32 Malignant neoplasm of larynx
0.739 0.261 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.739 0.261 0.000
S60 Superficial injury of wrist and hand
0.738 0.262 0.000
F80-F89 Disorders of psychological development
0.737 0.263 0.000
F11 Mental and behavioural disorders due to use of opioids
0.736 0.263 0.000
T91 Sequelae of injuries of neck and trunk
0.735 0.265 0.000
M06.0 Seronegative rheumatoid arthritis
0.734 0.266 0.000
F99-F99 Unspecified mental disorder
0.734 0.266 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.733 0.267 0.000
T00-T07 Injuries involving multiple body regions
0.730 0.270 0.000
D37.1 Stomach
0.730 0.270 0.000
M10.9 Gout, unspecified
0.727 0.273 0.000
F10.4 Withdrawal state with delirium
0.727 0.273 0.000
F02 Dementia in other diseases classified elsewhere
0.726 0.274 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.723 0.277 0.000
V10-V19 Pedal cyclist injured in transport accident
0.721 0.279 0.000
S64 Injury of nerves at wrist and hand level
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
F10.8 Other mental and behavioural disorders
0.717 0.283 0.000
F10.7 Residual and late-onset psychotic disorder
0.717 0.283 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
F10.5 Psychotic disorder
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C95 Leukaemia of unspecified cell type
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
C93 Monocytic leukaemia
0.715 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.715 0.285 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
M06.8 Other specified rheumatoid arthritis
0.713 0.287 0.000
M06.4 Inflammatory polyarthropathy
0.713 0.287 0.000
M06.3 Rheumatoid nodule
0.713 0.287 0.000
M06.2 Rheumatoid bursitis
0.713 0.287 0.000
M06.1 Adult-onset Still's disease
0.713 0.287 0.000
F43.0 Acute stress reaction
0.712 0.288 0.000
C50-C50 Malignant neoplasm of breast
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.712 0.288 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.712 0.288 0.000
G03 Meningitis due to other and unspecified causes
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.710 0.290 0.000
D05.7 Other carcinoma in situ of breast
0.709 0.291 0.000
M85.6 Other cyst of bone
0.709 0.291 0.000
S20 Superficial injury of thorax
0.709 0.291 0.000
D09 Carcinoma in situ of other and unspecified sites
0.707 0.293 0.000
G24.5 Blepharospasm
0.707 0.293 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.706 0.294 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.706 0.294 0.000
F43.2 Adjustment disorders
0.704 0.296 0.000
F48 Other neurotic disorders
0.704 0.296 0.000
F44 Dissociative [conversion] disorders
0.704 0.296 0.000
T40.6 Other and unspecified narcotics
0.704 0.296 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.703 0.297 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.703 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.701 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.699 0.301 0.000
G43 Migraine
0.699 0.301 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.698 0.302 0.000
G23 Other degenerative diseases of basal ganglia
0.698 0.302 0.000
G21 Secondary Parkinsonism
0.698 0.302 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.698 0.302 0.000
G22 Parkinsonism in diseases classified elsewhere
0.698 0.302 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.696 0.304 0.000
C83.7 Burkitt's tumour
0.696 0.304 0.000
C83.6 Undifferentiated (diffuse)
0.696 0.304 0.000
C83.5 Lymphoblastic (diffuse)
0.696 0.304 0.000
C83.4 Immunoblastic (diffuse)
0.696 0.304 0.000
C83.2 Mixed small and large cell (diffuse)
0.696 0.304 0.000
C83.1 Small cleaved cell (diffuse)
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
M83 Adult osteomalacia
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.695 0.305 0.000
Chapter I Certain infectious and parasitic diseases
0.695 0.305 0.000
T93 Sequelae of injuries of lower limb
0.691 0.309 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.688 0.311 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.688 0.311 0.000
D03 Melanoma in situ
0.688 0.312 0.000
C34.3 Lower lobe, bronchus or lung
0.688 0.312 0.000
C51 Malignant neoplasm of vulva
0.688 0.312 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.687 0.312 0.000
M11 Other crystal arthropathies
0.687 0.313 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.685 0.315 0.000
D02.0 Larynx
0.684 0.316 0.000
T98 Sequelae of other and unspecified effects of external causes
0.684 0.316 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.683 0.317 0.000
G90 Disorders of autonomic nervous system
0.682 0.318 0.000
T39.0 Salicylates
0.681 0.319 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.681 0.319 0.000
F09 Unspecified organic or symptomatic mental disorder
0.681 0.319 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.681 0.319 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.680 0.320 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.680 0.320 0.000
C31 Malignant neoplasm of accessory sinuses
0.680 0.320 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.680 0.320 0.000
C37 Malignant neoplasm of thymus
0.680 0.320 0.000
C33 Malignant neoplasm of trachea
0.680 0.320 0.000
G91 Hydrocephalus
0.679 0.321 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.679 0.321 0.000
C79.6 Secondary malignant neoplasm of ovary
0.677 0.323 0.000
S40 Superficial injury of shoulder and upper arm
0.676 0.324 0.000
V80-V89 Other land transport accidents
0.676 0.324 0.000
G93.9 Disorder of brain, unspecified
0.675 0.325 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.674 0.326 0.000
M91-M94 Chondropathies
0.674 0.326 0.000
T31.0 Burns involving less than 10% of body surface
0.674 0.326 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.673 0.327 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.671 0.329 0.000
C77.8 Lymph nodes of multiple regions
0.671 0.329 0.000
D37.7 Other digestive organs
0.670 0.330 0.000
C34.2 Middle lobe, bronchus or lung
0.669 0.330 0.000
F60.9 Personality disorder, unspecified
0.669 0.331 0.000
F42 Obsessive-compulsive disorder
0.668 0.332 0.000
F64 Gender identity disorders
0.667 0.333 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.666 0.334 0.000
C58 Malignant neoplasm of placenta
0.666 0.334 0.000
C52 Malignant neoplasm of vagina
0.666 0.334 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.665 0.335 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.665 0.335 0.000
M49 Spondylopathies in diseases classified elsewhere
0.663 0.337 0.000
C91.4 Hairy-cell leukaemia
0.663 0.337 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.662 0.338 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.661 0.339 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.661 0.339 0.000
F41.8 Other specified anxiety disorders
0.660 0.340 0.000
F41.3 Other mixed anxiety disorders
0.660 0.340 0.000
G93.3 Postviral fatigue syndrome
0.659 0.341 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.658 0.342 0.000
T40.8 Lysergide [LSD]
0.658 0.342 0.000
T40.7 Cannabis (derivatives)
0.658 0.342 0.000
T40.5 Cocaine
0.658 0.342 0.000
T40.4 Other synthetic narcotics
0.658 0.342 0.000
T40.3 Methadone
0.658 0.342 0.000
T40.1 Heroin
0.658 0.342 0.000
T40.0 Opium
0.658 0.342 0.000
D37.0 Lip, oral cavity and pharynx
0.657 0.343 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.656 0.344 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.656 0.344 0.000
S19 Other and unspecified injuries of neck
0.654 0.346 0.000
S70-S79 Injuries to the hip and thigh
0.653 0.347 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.652 0.348 0.000
C80.9 Malignant neoplasm, unspecified
0.652 0.348 0.000
X50-X57 Overexertion, travel and privation
0.651 0.349 0.000
Q60-Q64 Congenital malformations of the urinary system
0.651 0.349 0.000
G24.8 Other dystonia
0.650 0.350 0.000
G24.4 Idiopathic orofacial dystonia
0.650 0.350 0.000
G24.2 Idiopathic nonfamilial dystonia
0.650 0.350 0.000
G24.1 Idiopathic familial dystonia
0.650 0.350 0.000
G24.0 Drug-induced dystonia
0.650 0.350 0.000
G43.9 Migraine, unspecified
0.648 0.352 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.647 0.353 0.000
G00 Bacterial meningitis, not elsewhere classified
0.647 0.353 0.000
C34.8 Overlapping lesion of bronchus and lung
0.647 0.353 0.000
C71 Malignant neoplasm of brain
0.647 0.353 0.000
S59 Other and unspecified injuries of forearm
0.646 0.354 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.646 0.354 0.000
M46 Other inflammatory spondylopathies
0.645 0.355 0.000
T21 Burn and corrosion of trunk
0.645 0.355 0.000
F40.9 Phobic anxiety disorder, unspecified
0.645 0.355 0.000
F40.8 Other phobic anxiety disorders
0.645 0.355 0.000
F40.1 Social phobias
0.645 0.355 0.000
F40.0 Agoraphobia
0.645 0.355 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.645 0.355 0.000
C91.0 Acute lymphoblastic leukaemia
0.643 0.357 0.000
G72 Other myopathies
0.643 0.357 0.000
M41 Scoliosis
0.642 0.358 0.000
D46 Myelodysplastic syndromes
0.641 0.358 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.641 0.359 0.000
F01 Vascular dementia
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.640 0.360 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.640 0.360 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.640 0.360 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.639 0.361 0.000
G40 Epilepsy
0.639 0.361 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.639 0.361 0.000
M62 Other disorders of muscle
0.638 0.362 0.000
D40.0 Prostate
0.638 0.362 0.000
G93.5 Compression of brain
0.638 0.362 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.638 0.362 0.000
T43.9 Psychotropic drug, unspecified
0.637 0.362 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.637 0.362 0.000
T43.6 Psychostimulants with abuse potential
0.637 0.362 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.637 0.362 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.637 0.362 0.000
T68 Hypothermia
0.637 0.363 0.000
C54.9 Corpus uteri, unspecified
0.636 0.364 0.000
C54.8 Overlapping lesion of corpus uteri
0.636 0.364 0.000
C54.3 Fundus uteri
0.636 0.364 0.000
C54.2 Myometrium
0.636 0.364 0.000
C54.0 Isthmus uteri
0.636 0.364 0.000
S90-S99 Injuries to the ankle and foot
0.635 0.364 0.000
G93.6 Cerebral oedema
0.635 0.365 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.633 0.367 0.000
D37.9 Digestive organ, unspecified
0.632 0.367 0.000
D37.3 Appendix
0.632 0.367 0.000
S10 Superficial injury of neck
0.631 0.368 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.631 0.368 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.631 0.369 0.000
W20-W49 Exposure to inanimate mechanical forces
0.631 0.369 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.631 0.369 0.000
C85.0 Lymphosarcoma
0.631 0.369 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.631 0.369 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.630 0.370 0.000
T50.8 Diagnostic agents
0.630 0.370 0.000
T50.7 Analeptics and opioid receptor antagonists
0.630 0.370 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.630 0.370 0.000
T50.5 Appetite depressants
0.630 0.370 0.000
T50.4 Drugs affecting uric acid metabolism
0.630 0.370 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.630 0.370 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.630 0.370 0.000
T50.1 Loop [high-ceiling] diuretics
0.630 0.370 0.000
T50.0 Mineralocorticoids and their antagonists
0.630 0.370 0.000
F68 Other disorders of adult personality and behaviour
0.629 0.371 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.629 0.371 0.000
F65 Disorders of sexual preference
0.629 0.371 0.000
F63 Habit and impulse disorders
0.629 0.371 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.629 0.371 0.000
F69 Unspecified disorder of adult personality and behaviour
0.629 0.371 0.000
F61 Mixed and other personality disorders
0.629 0.371 0.000
M85.9 Disorder of bone density and structure, unspecified
0.628 0.371 0.000
M85.5 Aneurysmal bone cyst
0.628 0.371 0.000
M85.4 Solitary bone cyst
0.628 0.371 0.000
M85.3 Osteitis condensans
0.628 0.371 0.000
M85.2 Hyperostosis of skull
0.628 0.371 0.000
M85.1 Skeletal fluorosis
0.628 0.371 0.000
S65 Injury of blood vessels at wrist and hand level
0.628 0.372 0.000
T20 Burn and corrosion of head and neck
0.627 0.373 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.627 0.373 0.000
W50-W64 Exposure to animate mechanical forces
0.627 0.373 0.000
S60.0 Contusion of finger(s) without damage to nail
0.627 0.373 0.000
D05.1 Intraductal carcinoma in situ
0.626 0.374 0.000
C92.1 Chronic myeloid leukaemia
0.625 0.375 0.000
T92.1 Sequelae of fracture of arm
0.625 0.375 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.624 0.376 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.624 0.376 0.000
D06.7 Other parts of cervix
0.624 0.376 0.000
D06.1 Exocervix
0.624 0.376 0.000
D06.0 Endocervix
0.624 0.376 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.623 0.377 0.000
D07.5 Prostate
0.623 0.377 0.000
O00-O08 Pregnancy with abortive outcome
0.622 0.378 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.622 0.378 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.622 0.378 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.622 0.378 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G92 Toxic encephalopathy
0.622 0.378 0.000
C53.0 Endocervix
0.621 0.379 0.000
D38.1 Trachea, bronchus and lung
0.621 0.379 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.621 0.379 0.000
M80.8 Other osteoporosis with pathological fracture
0.621 0.379 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.621 0.379 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.621 0.379 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.621 0.379 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.621 0.379 0.000
S50 Superficial injury of forearm
0.619 0.381 0.000
M05.8 Other seropositive rheumatoid arthritis
0.618 0.382 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.618 0.382 0.000
M05.2 Rheumatoid vasculitis
0.618 0.382 0.000
M05.1 Rheumatoid lung disease
0.618 0.382 0.000
M05.0 Felty's syndrome
0.618 0.382 0.000
D40.1 Testis
0.618 0.382 0.000
S42 Fracture of shoulder and upper arm
0.618 0.382 0.000
C34.0 Main bronchus
0.617 0.383 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.617 0.383 0.000
F60.3 Emotionally unstable personality disorder
0.617 0.383 0.000
C77.4 Inguinal and lower limb lymph nodes
0.617 0.383 0.000
G30.8 Other Alzheimer's disease
0.616 0.384 0.000
G30.1 Alzheimer's disease with late onset
0.616 0.384 0.000
G30.0 Alzheimer's disease with early onset
0.616 0.384 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.616 0.384 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.616 0.384 0.000
T36.0 Penicillins
0.616 0.384 0.000
T59 Toxic effect of other gases, fumes and vapours
0.615 0.385 0.000
C81.9 Hodgkin's disease, unspecified
0.615 0.385 0.000
Y00-Y09 Assault
0.614 0.386 0.000
S60.2 Contusion of other parts of wrist and hand
0.614 0.386 0.000
F43.9 Reaction to severe stress, unspecified
0.613 0.387 0.000
F43.8 Other reactions to severe stress
0.613 0.387 0.000
M07.3 Other psoriatic arthropathies
0.613 0.387 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.612 0.388 0.000
B35-B49 Mycoses
0.612 0.388 0.000
F43.1 Posttraumatic stress disorder
0.612 0.388 0.000
T32 Corrosions classified according to extent of body surface involved
0.612 0.388 0.000
T30 Burn and corrosion, body region unspecified
0.612 0.388 0.000
T29 Burns and corrosions of multiple body regions
0.612 0.388 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.612 0.388 0.000
D04.6 Skin of upper limb, including shoulder
0.612 0.388 0.000
C84.5 Other and unspecified T-cell lymphomas
0.611 0.389 0.000
G03.9 Meningitis, unspecified
0.611 0.389 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.610 0.390 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.610 0.390 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.610 0.390 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.610 0.390 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.610 0.390 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.610 0.390 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.610 0.390 0.000
D04.7 Skin of lower limb, including hip
0.610 0.390 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.610 0.390 0.000
M84.9 Disorder of continuity of bone, unspecified
0.609 0.391 0.000
M84.8 Other disorders of continuity of bone
0.609 0.391 0.000
M84.4 Pathological fracture, not elsewhere classified
0.609 0.391 0.000
M84.3 Stress fracture, not elsewhere classified
0.609 0.391 0.000
M84.2 Delayed union of fracture
0.609 0.391 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.608 0.392 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.607 0.393 0.000
X60-X84 Intentional self-harm
0.607 0.393 0.000
O03 Spontaneous abortion
0.605 0.395 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.604 0.396 0.000
C82.6 Cutaneous follicle centre lymphoma
0.604 0.396 0.000
C82.5 Diffuse follicle centre lymphoma
0.604 0.396 0.000
C82.4 Follicular lymphoma grade IIIb
0.604 0.396 0.000
C82.3 Follicular lymphoma grade IIIa
0.604 0.396 0.000
C82.2 Large cell, follicular
0.604 0.396 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.604 0.396 0.000
C82.0 Small cleaved cell, follicular
0.604 0.396 0.000
T23 Burn and corrosion of wrist and hand
0.604 0.396 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.604 0.396 0.000
T51 Toxic effect of alcohol
0.603 0.396 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.602 0.398 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.602 0.398 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.602 0.398 0.000
T42.3 Barbiturates
0.602 0.398 0.000
T42.2 Succinimides and oxazolidinediones
0.602 0.398 0.000
T42.1 Iminostilbenes
0.602 0.398 0.000
T42.0 Hydantoin derivatives
0.602 0.398 0.000
M10.4 Other secondary gout
0.602 0.398 0.000
M10.3 Gout due to impairment of renal function
0.602 0.398 0.000
M10.2 Drug-induced gout
0.602 0.398 0.000
M10.1 Lead-induced gout
0.602 0.398 0.000
M10.0 Idiopathic gout
0.602 0.398 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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