TreeWAS – Variant ID: rs853308

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.038	0.962
E03 Other hypothyroidism	0.001	0.599	0.400
E03.1 Congenital hypothyroidism without goitre	0.000	0.659	0.341
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.710	0.289
E03.5 Myxoedema coma	0.001	0.712	0.287
E03.4 Atrophy of thyroid (acquired)	0.001	0.712	0.287
E03.3 Postinfectious hypothyroidism	0.001	0.712	0.287
E03.8 Other specified hypothyroidism	0.001	0.758	0.241
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.760	0.239
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.883	0.117
K86 Other diseases of pancreas	0.000	0.885	0.115
K86.1 Other chronic pancreatitis	0.000	0.891	0.109
K86.2 Cyst of pancreas	0.000	0.891	0.109
K86.3 Pseudocyst of pancreas	0.000	0.905	0.095
K86.8 Other specified diseases of pancreas	0.000	0.912	0.088
K86.9 Disease of pancreas, unspecified	0.000	0.915	0.085
I21.0 Acute transmural myocardial infarction of anterior wall	0.060	0.940	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.036	0.964	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.035	0.965	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.035	0.965	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.033	0.967	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.032	0.968	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.031	0.969	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.030	0.970	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.029	0.971	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.029	0.971	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.028	0.972	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.028	0.972	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.028	0.972	0.000
T50.4 Drugs affecting uric acid metabolism	0.027	0.973	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.027	0.973	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.027	0.973	0.000
T39.0 Salicylates	0.027	0.973	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.027	0.973	0.000
T36 Poisoning by systemic antibiotics	0.027	0.973	0.000
T42.1 Iminostilbenes	0.027	0.973	0.000
T42.0 Hydantoin derivatives	0.026	0.973	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.026	0.974	0.000
T50.8 Diagnostic agents	0.026	0.974	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.026	0.974	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.026	0.974	0.000
E04.1 Non-toxic single thyroid nodule	0.026	0.974	0.000
T50.1 Loop [high-ceiling] diuretics	0.025	0.975	0.000
T50.7 Analeptics and opioid receptor antagonists	0.025	0.975	0.000
T50.5 Appetite depressants	0.025	0.975	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.025	0.975	0.000
T50.0 Mineralocorticoids and their antagonists	0.025	0.975	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.025	0.975	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.024	0.976	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.024	0.976	0.000
T42.2 Succinimides and oxazolidinediones	0.024	0.976	0.000
T46.1 Calcium-channel blockers	0.024	0.976	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.024	0.976	0.000
T38.1 Thyroid hormones and substitutes	0.023	0.977	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.023	0.977	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.023	0.977	0.000
T42.3 Barbiturates	0.023	0.977	0.000
T38.9 Other and unspecified hormone antagonists	0.023	0.977	0.000
T38.7 Androgens and anabolic congeners	0.023	0.977	0.000
T38.5 Other oestrogens and progestogens	0.023	0.977	0.000
T38.4 Oral contraceptives	0.023	0.977	0.000
T38.2 Antithyroid drugs	0.023	0.977	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.022	0.977	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.022	0.977	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.022	0.978	0.000
T36.3 Macrolides	0.022	0.978	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.022	0.978	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.022	0.978	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.022	0.978	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.022	0.978	0.000
T38.0 Glucocorticoids and synthetic analogues	0.022	0.978	0.000
T47.2 Stimulant laxatives	0.022	0.978	0.000
T49.9 Topical agent, unspecified	0.022	0.978	0.000
T49.8 Other topical agents	0.022	0.978	0.000
T49.7 Dental drugs, topically applied	0.022	0.978	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.022	0.978	0.000
T49.5 Ophthalmological drugs and preparations	0.022	0.978	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.022	0.978	0.000
T49.3 Emollients, demulcents and protectants	0.022	0.978	0.000
T49.2 Local astringents and local detergents	0.022	0.978	0.000
T49.1 Antipruritics	0.022	0.978	0.000
T40.2 Other opioids	0.022	0.978	0.000
T51.9 Alcohol, unspecified	0.022	0.978	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.021	0.978	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.021	0.979	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.021	0.979	0.000
T46.7 Peripheral vasodilators	0.021	0.979	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.021	0.979	0.000
T47.4 Other laxatives	0.021	0.979	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.021	0.979	0.000
T47.0 Histamine H(2)-receptor antagonists	0.021	0.979	0.000
T39.4 Antirheumatics, not elsewhere classified	0.021	0.979	0.000
T39.2 Pyrazolone derivatives	0.021	0.979	0.000
T36.8 Other systemic antibiotics	0.020	0.979	0.000
T47.6 Antidiarrhoeal drugs	0.020	0.979	0.000
T40.3 Methadone	0.020	0.979	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.020	0.979	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.020	0.980	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.020	0.980	0.000
T47.7 Emetics	0.020	0.980	0.000
T47.5 Digestants	0.020	0.980	0.000
T47.3 Saline and osmotic laxatives	0.020	0.980	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.020	0.980	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.020	0.980	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.020	0.980	0.000
T44.0 Anticholinesterase agents	0.020	0.980	0.000
T40.1 Heroin	0.020	0.980	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.020	0.980	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.020	0.980	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.020	0.980	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.020	0.980	0.000
T48.5 Anti-common-cold drugs	0.020	0.980	0.000
T48.4 Expectorants	0.020	0.980	0.000
T48.3 Antitussives	0.020	0.980	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.020	0.980	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.020	0.980	0.000
T48.0 Oxytocic drugs	0.020	0.980	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.020	0.980	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.020	0.980	0.000
T37.5 Antiviral drugs	0.020	0.980	0.000
T37.4 Anthelminthics	0.020	0.980	0.000
T37.3 Other antiprotozoal drugs	0.020	0.980	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.020	0.980	0.000
T37.1 Antimycobacterial drugs	0.020	0.980	0.000
T37.0 Sulphonamides	0.020	0.980	0.000
T40.4 Other synthetic narcotics	0.020	0.980	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.020	0.980	0.000
T40.8 Lysergide [LSD]	0.020	0.980	0.000
T40.7 Cannabis (derivatives)	0.020	0.980	0.000
T40.0 Opium	0.020	0.980	0.000
T36.9 Systemic antibiotic, unspecified	0.019	0.980	0.000
T36.7 Antifungal antibiotics, systemically used	0.019	0.980	0.000
T36.6 Rifamycins	0.019	0.980	0.000
T36.5 Aminoglycosides	0.019	0.980	0.000
T36.2 Chloramphenicol group	0.019	0.980	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.019	0.980	0.000
K73.9 Chronic hepatitis, unspecified	0.019	0.981	0.000
T40.5 Cocaine	0.019	0.981	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T36.4 Tetracyclines	0.019	0.981	0.000
T41.5 Therapeutic gases	0.018	0.981	0.000
T41.4 Anaesthetic, unspecified	0.018	0.981	0.000
T41.3 Local anaesthetics	0.018	0.981	0.000
T41.2 Other and unspecified general anaesthetics	0.018	0.981	0.000
T41.1 Intravenous anaesthetics	0.018	0.981	0.000
T41.0 Inhaled anaesthetics	0.018	0.981	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.018	0.982	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.017	0.983	0.000
T43.6 Psychostimulants with abuse potential	0.017	0.983	0.000
T36.0 Penicillins	0.017	0.983	0.000
T51 Toxic effect of alcohol	0.017	0.983	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.017	0.983	0.000
T39.1 4-Aminophenol derivatives	0.016	0.984	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.016	0.984	0.000
T45.8 Other primarily systemic and haematological agents	0.016	0.984	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.016	0.984	0.000
T45.6 Fibrinolysis-affecting drugs	0.016	0.984	0.000
T45.4 Iron and its compounds	0.016	0.984	0.000
T45.3 Enzymes, not elsewhere classified	0.016	0.984	0.000
T45.5 Anticoagulants	0.016	0.984	0.000
T40.6 Other and unspecified narcotics	0.016	0.984	0.000
T51.0 Ethanol	0.016	0.984	0.000
T45.2 Vitamins, not elsewhere classified	0.015	0.985	0.000
K56.7 Ileus, unspecified	0.000	0.986	0.014
T43.9 Psychotropic drug, unspecified	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.014	0.986	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.987	0.013
T43.2 Other and unspecified antidepressants	0.013	0.987	0.000
T51.8 Other alcohols	0.012	0.988	0.000
T51.3 Fusel oil	0.012	0.988	0.000
T51.2 2-Propanol	0.012	0.988	0.000
T51.1 Methanol	0.012	0.988	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.988	0.012
T43.0 Tricyclic and tetracyclic antidepressants	0.012	0.988	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.011	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.010	0.989	0.000
K73 Chronic hepatitis, not elsewhere classified	0.011	0.989	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.989	0.011
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
T42.4 Benzodiazepines	0.009	0.991	0.000
E00-E07 Disorders of thyroid gland	0.003	0.991	0.006
K73.2 Chronic active hepatitis, not elsewhere classified	0.009	0.991	0.000
N92.4 Excessive bleeding in the premenopausal period	0.009	0.991	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.008	0.992	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.008	0.992	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.008	0.992	0.000
N32.9 Bladder disorder, unspecified	0.000	0.993	0.007
H52.2 Astigmatism	0.000	0.993	0.007
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.993	0.005
E00 Congenital iodine-deficiency syndrome	0.002	0.993	0.005
E04 Other non-toxic goitre	0.006	0.994	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.994	0.004
G82.2 Paraplegia, unspecified	0.006	0.994	0.000
K41 Femoral hernia	0.000	0.995	0.005
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.995	0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.995	0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.995	0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.995	0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.995	0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.995	0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.995	0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.995	0.004
H52.3 Anisometropia and aniseikonia	0.000	0.995	0.005
E06 Thyroiditis	0.002	0.995	0.004
G82 Paraplegia and tetraplegia	0.005	0.995	0.000
E07 Other disorders of thyroid	0.003	0.995	0.002
G82.1 Spastic paraplegia	0.005	0.995	0.000
E04.8 Other specified non-toxic goitre	0.004	0.995	0.001
D48.5 Skin	0.005	0.995	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.995	0.005
H52 Disorders of refraction and accommodation	0.000	0.995	0.005
E07.8 Other specified disorders of thyroid	0.004	0.995	0.001
E04.0 Non-toxic diffuse goitre	0.004	0.996	0.000
H52.0 Hypermetropia	0.000	0.996	0.004
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.996	0.004
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.996	0.004
D07.1 Vulva	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.996	0.004
E06.5 Other chronic thyroiditis	0.001	0.996	0.003
E06.4 Drug-induced thyroiditis	0.001	0.996	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.996	0.003
E06.0 Acute thyroiditis	0.001	0.996	0.003
G82.5 Tetraplegia, unspecified	0.004	0.996	0.000
G82.3 Flaccid tetraplegia	0.004	0.996	0.000
G82.0 Flaccid paraplegia	0.004	0.996	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.996	0.004
E07.1 Dyshormogenetic goitre	0.003	0.996	0.001
E07.0 Hypersecretion of calcitonin	0.003	0.996	0.001
E06.1 Subacute thyroiditis	0.001	0.996	0.002
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.004	0.996	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.996	0.004
K29.5 Chronic gastritis, unspecified	0.004	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.004	0.996	0.000
G80 Infantile cerebral palsy	0.004	0.996	0.000
H52.6 Other disorders of refraction	0.000	0.996	0.003
H52.5 Disorders of accommodation	0.000	0.996	0.003
G80-G83 Cerebral palsy and other paralytic syndromes	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.003	0.997	0.000
T59 Toxic effect of other gases, fumes and vapours	0.003	0.997	0.000
W29.9 Unspecified place	0.003	0.997	0.000
I21 Acute myocardial infarction	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
G54.0 Brachial plexus disorders	0.000	0.997	0.003
E06.9 Thyroiditis, unspecified	0.001	0.997	0.002
M45 Ankylosing spondylitis	0.000	0.997	0.003
T54 Toxic effect of corrosive substances	0.003	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.997	0.003
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.997	0.003
C67.6 Ureteric orifice	0.000	0.997	0.003
T62 Toxic effect of other noxious substances eaten as food	0.003	0.997	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.003	0.997	0.000
T60 Toxic effect of pesticides	0.003	0.997	0.000
T57 Toxic effect of other inorganic substances	0.003	0.997	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.003	0.997	0.000
T52 Toxic effect of organic solvents	0.003	0.997	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.003	0.997	0.000
T55 Toxic effect of soaps and detergents	0.003	0.997	0.000
G80.1 Spastic diplegia	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.997	0.003
T65 Toxic effect of other and unspecified substances	0.003	0.997	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.997	0.003
G80.2 Infantile hemiplegia	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.001	0.997	0.002
T59.8 Other specified gases, fumes and vapours	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.000	0.997	0.003
T56 Toxic effect of metals	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
G80.8 Other infantile cerebral palsy	0.003	0.997	0.000
N21.0 Calculus in bladder	0.000	0.997	0.003
J95.8 Other postprocedural respiratory disorders	0.000	0.997	0.003
G80.4 Ataxic cerebral palsy	0.003	0.997	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.997	0.000
K56.0 Paralytic ileus	0.000	0.997	0.003
G81 Hemiplegia	0.003	0.997	0.000
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
H52.4 Presbyopia	0.000	0.997	0.002
K56.1 Intussusception	0.000	0.997	0.003
T59.7 Carbon dioxide	0.003	0.997	0.000
T59.6 Hydrogen sulphide	0.003	0.997	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.003	0.997	0.000
T59.4 Chlorine gas	0.003	0.997	0.000
T59.3 Lachrymogenic gas	0.003	0.997	0.000
T59.2 Formaldehyde	0.003	0.997	0.000
T59.1 Sulphur dioxide	0.003	0.997	0.000
T59.0 Nitrogen oxides	0.003	0.997	0.000
T54.9 Corrosive substance, unspecified	0.003	0.997	0.000
T63 Toxic effect of contact with venomous animals	0.003	0.997	0.000
H57.1 Ocular pain	0.000	0.997	0.003
I21.X Presumed acute myicardial infaction (unconfirmed)	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.997	0.003
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.997	0.003
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.997	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.997	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.997	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.997	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.997	0.002
T54.3 Corrosive alkalis and alklali-like substances	0.002	0.997	0.000
T54.2 Corrosive acids and acid-like substances	0.002	0.997	0.000
T54.1 Other corrosive organic compounds	0.002	0.997	0.000
T54.0 Phenol and phenol homologues	0.002	0.997	0.000
T59.9 Gases, fumes and vapours, unspecified	0.002	0.997	0.000
C67 Malignant neoplasm of bladder	0.000	0.997	0.003
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.001	0.997	0.002
E05.4 Thyrotoxicosis factitia	0.001	0.997	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.997	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
C67.9 Bladder, unspecified	0.000	0.997	0.003
T52.9 Organic solvent, unspecified	0.002	0.997	0.000
T52.8 Other organic solvents	0.002	0.997	0.000
T52.4 Ketones	0.002	0.997	0.000
T52.3 Glycols	0.002	0.997	0.000
T52.2 Homologues of benzene	0.002	0.997	0.000
T52.1 Benzene	0.002	0.997	0.000
T52.0 Petroleum products	0.002	0.997	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.002	0.997	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.002	0.997	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.002	0.997	0.000
T53.5 Chlorofluorocarbons	0.002	0.997	0.000
T53.4 Dichloromethane	0.002	0.997	0.000
T53.3 Tetrachloroethylene	0.002	0.997	0.000
T53.2 Trichloroethylene	0.002	0.997	0.000
T53.1 Chloroform	0.002	0.997	0.000
T53.0 Carbon tetrachloride	0.002	0.997	0.000
T57.9 Inorganic substance, unspecified	0.002	0.997	0.000
T57.8 Other specified inorganic substances	0.002	0.997	0.000
T57.3 Hydrogen cyanide	0.002	0.997	0.000
T57.2 Manganese and its compounds	0.002	0.997	0.000
T57.1 Phosphorus and its compounds	0.002	0.997	0.000
T57.0 Arsenic and its compounds	0.002	0.997	0.000
T60.9 Pesticide, unspecified	0.002	0.997	0.000
T60.8 Other pesticides	0.002	0.997	0.000
T60.4 Rodenticides	0.002	0.997	0.000
T60.3 Herbicides and fungicides	0.002	0.997	0.000
T60.2 Other insecticides	0.002	0.997	0.000
T60.1 Halogenated insecticides	0.002	0.997	0.000
T60.0 Organophosphate and carbamate insecticides	0.002	0.997	0.000
T61.9 Toxic effect of unspecified seafood	0.002	0.997	0.000
T61.8 Toxic effect of other seafoods	0.002	0.997	0.000
T61.2 Other fish and shellfish poisoning	0.002	0.997	0.000
T61.1 Scombroid fish poisoning	0.002	0.997	0.000
T61.0 Ciguatera fish poisoning	0.002	0.997	0.000
T62.9 Noxious substance eaten as food, unspecified	0.002	0.997	0.000
T62.8 Other specified noxious substances eaten as food	0.002	0.997	0.000
T62.2 Other ingested (parts of) plant(s)	0.002	0.997	0.000
T62.1 Ingested berries	0.002	0.997	0.000
T62.0 Ingested mushrooms	0.002	0.997	0.000
S22.20 Fracture of sternum (closed)	0.000	0.997	0.003
C67.0 Trigone of bladder	0.000	0.997	0.003
N60.4 Mammary duct ectasia	0.003	0.997	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.002	0.997	0.000
T65.8 Toxic effect of other specified substances	0.002	0.997	0.000
T65.6 Paints and dyes, not elsewhere classified	0.002	0.997	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.002	0.997	0.000
T65.4 Carbon disulphide	0.002	0.997	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.002	0.997	0.000
T65.2 Tobacco and nicotine	0.002	0.997	0.000
T65.1 Strychnine and its salts	0.002	0.997	0.000
T65.0 Cyanides	0.002	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.998	0.002
G83 Other paralytic syndromes	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.002	0.998	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.002
K56.3 Gallstone ileus	0.000	0.998	0.002
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
T65.9 Toxic effect of unspecified substance	0.002	0.998	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.998	0.002
T56.9 Metal, unspecified	0.002	0.998	0.000
T56.7 Beryllium and its compounds	0.002	0.998	0.000
T56.6 Tin and its compounds	0.002	0.998	0.000
T56.5 Zinc and its compounds	0.002	0.998	0.000
T56.4 Copper and its compounds	0.002	0.998	0.000
T56.3 Cadmium and its compounds	0.002	0.998	0.000
T56.2 Chromium and its compounds	0.002	0.998	0.000
T56.1 Mercury and its compounds	0.002	0.998	0.000
T56.0 Lead and its compounds	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.001	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.002	0.998	0.000
R07.0 Pain in throat	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.002	0.998	0.000
T63.8 Toxic effect of contact with other venomous animals	0.002	0.998	0.000
T63.6 Toxic effect of contact with other marine animals	0.002	0.998	0.000
T63.5 Toxic effect of contact with fish	0.002	0.998	0.000
T63.3 Venom of spider	0.002	0.998	0.000
T63.2 Venom of scorpion	0.002	0.998	0.000
T63.1 Venom of other reptiles	0.002	0.998	0.000
T63.0 Snake venom	0.002	0.998	0.000
W22.9 Unspecified place	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.000	0.998	0.002
G81.9 Hemiplegia, unspecified	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.000	0.998	0.002
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
C67.7 Urachus	0.000	0.998	0.002
K74.4 Secondary biliary cirrhosis	0.002	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.998	0.000
T56.8 Other metals	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
C67.5 Bladder neck	0.000	0.998	0.002
K56.6 Other and unspecified intestinal obstruction	0.000	0.998	0.002
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
T58 Toxic effect of carbon monoxide	0.002	0.998	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.002	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.002	0.998	0.000
G83.5 Locked-in syndrome	0.002	0.998	0.000
G83.3 Monoplegia, unspecified	0.002	0.998	0.000
G83.0 Diplegia of upper limbs	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
K77 Liver disorders in diseases classified elsewhere	0.002	0.998	0.000
G83.9 Paralytic syndrome, unspecified	0.002	0.998	0.000
S69 Other and unspecified injuries of wrist and hand	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
I51.7 Cardiomegaly	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.002	0.998	0.000
C24.9 Biliary tract, unspecified	0.002	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
K70-K77 Diseases of liver	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.000	0.998	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.002	0.998	0.000
C24.0 Extrahepatic bile duct	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.002	0.998	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.002	0.998	0.000
E24 Cushing's syndrome	0.000	0.998	0.002
T13.8 Other specified injuries of lower limb, level unspecified	0.002	0.998	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.002	0.998	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.002	0.998	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.002	0.998	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
N21.1 Calculus in urethra	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
S69.8 Other specified injuries of wrist and hand	0.002	0.998	0.000
T63.4 Venom of other arthropods	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.000	0.998	0.002
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.998	0.002
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
C24.1 Ampulla of Vater	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
N93.0 Postcoital and contact bleeding	0.000	0.998	0.002
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
L98.0 Pyogenic granuloma	0.002	0.998	0.000
N21 Calculus of lower urinary tract	0.000	0.998	0.002
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.998	0.002
C84.0 Mycosis fungoides	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.001
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.001
E24.1 Nelson's syndrome	0.000	0.998	0.001
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.002	0.998	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.002	0.998	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.001	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.998	0.002
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.002	0.998	0.000
F10.3 Withdrawal state	0.002	0.998	0.000
G90.3 Multisystem degeneration	0.001	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations