TreeWAS – Variant ID: rs881858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.748	0.252	0.000
E03 Other hypothyroidism	0.528	0.472	0.000
E03.8 Other specified hypothyroidism	0.484	0.516	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.402	0.598	0.000
E03.5 Myxoedema coma	0.378	0.621	0.000
E03.4 Atrophy of thyroid (acquired)	0.378	0.621	0.000
E03.3 Postinfectious hypothyroidism	0.378	0.621	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.368	0.631	0.000
E03.1 Congenital hypothyroidism without goitre	0.355	0.645	0.000
N75.1 Abscess of Bartholin's gland	0.122	0.878	0.000
N75 Diseases of Bartholin's gland	0.110	0.890	0.000
N70 Salpingitis and oophoritis	0.101	0.899	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.101	0.899	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.100	0.900	0.000
N76 Other inflammation of vagina and vulva	0.097	0.903	0.000
N76.0 Acute vaginitis	0.088	0.912	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.085	0.915	0.000
N76.4 Abscess of vulva	0.084	0.916	0.000
N70.0 Acute salpingitis and oophoritis	0.082	0.918	0.000
N75.8 Other diseases of Bartholin's gland	0.081	0.919	0.000
N76.8 Other specified inflammation of vagina and vulva	0.080	0.920	0.000
N76.1 Subacute and chronic vaginitis	0.079	0.921	0.000
N76.5 Ulceration of vagina	0.077	0.923	0.000
N70.1 Chronic salpingitis and oophoritis	0.075	0.925	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.072	0.928	0.000
N71 Inflammatory disease of uterus, except cervix	0.071	0.929	0.000
N75.0 Cyst of Bartholin's gland	0.071	0.929	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.069	0.931	0.000
N76.6 Ulceration of vulva	0.065	0.935	0.000
N76.2 Acute vulvitis	0.062	0.938	0.000
N76.3 Subacute and chronic vulvitis	0.057	0.943	0.000
N71.0 Acute inflammatory disease of uterus	0.055	0.945	0.000
N73 Other female pelvic inflammatory diseases	0.055	0.945	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.052	0.948	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.052	0.948	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.052	0.948	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.052	0.948	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.052	0.948	0.000
N74.0 Tuberculous infection of cervix uteri	0.052	0.948	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.050	0.950	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.050	0.950	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.049	0.950	0.000
N71.1 Chronic inflammatory disease of uterus	0.048	0.952	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.047	0.953	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.045	0.955	0.000
K83.8 Other specified diseases of biliary tract	0.042	0.958	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.042	0.958	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.039	0.960	0.000
N73.4 Female chronic pelvic peritonitis	0.039	0.961	0.000
N73.3 Female acute pelvic peritonitis	0.039	0.961	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.039	0.961	0.000
K86 Other diseases of pancreas	0.038	0.962	0.000
K83 Other diseases of biliary tract	0.038	0.962	0.000
K86.1 Other chronic pancreatitis	0.037	0.963	0.000
N73.5 Female pelvic peritonitis, unspecified	0.035	0.965	0.000
K86.2 Cyst of pancreas	0.035	0.965	0.000
K86.3 Pseudocyst of pancreas	0.035	0.965	0.000
K86.9 Disease of pancreas, unspecified	0.033	0.967	0.000
N73.6 Female pelvic peritoneal adhesions	0.033	0.967	0.000
K83.0 Cholangitis	0.031	0.969	0.000
K83.9 Disease of biliary tract, unspecified	0.031	0.969	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.031	0.969	0.000
K83.3 Fistula of bile duct	0.031	0.969	0.000
K83.1 Obstruction of bile duct	0.030	0.970	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.029	0.971	0.000
K85 Acute pancreatitis	0.028	0.972	0.000
K83.5 Biliary cyst	0.025	0.974	0.000
Z00.5 Examination of potential donor of organ and tissue	0.025	0.975	0.000
K85.1 Biliary acute pancreatitis	0.025	0.975	0.000
K83.2 Perforation of bile duct	0.024	0.975	0.000
K83.4 Spasm of sphincter of Oddi	0.024	0.976	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.023	0.977	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.022	0.977	0.000
K85.8 Other acute pancreatitis	0.022	0.978	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.022	0.978	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.022	0.978	0.000
K85.9 Acute pancreatitis, unspecified	0.022	0.978	0.000
K85.0 Idiopathic acute pancreatitis	0.022	0.978	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.021	0.979	0.000
I10 Essential (primary) hypertension	0.020	0.980	0.000
K86.8 Other specified diseases of pancreas	0.020	0.980	0.000
E00-E07 Disorders of thyroid gland	0.019	0.980	0.000
K85.3 Drug-induced acute pancreatitis	0.019	0.981	0.000
K85.2 Alcohol-induced acute pancreatitis	0.017	0.982	0.000
Z00.3 Examination for adolescent development state	0.017	0.983	0.000
Z00.2 Examination for period of rapid growth in childhood	0.017	0.983	0.000
Z00.1 Routine child health examination	0.017	0.983	0.000
Z00.8 Other general examinations	0.017	0.983	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.015	0.984	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.015	0.984	0.000
K08.3 Retained dental root	0.015	0.985	0.000
J32.9 Chronic sinusitis, unspecified	0.015	0.985	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.014	0.986	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E00 Congenital iodine-deficiency syndrome	0.014	0.986	0.000
Z00.0 General medical examination	0.014	0.986	0.000
E07 Other disorders of thyroid	0.014	0.986	0.000
S22.20 Fracture of sternum (closed)	0.000	0.986	0.014
K08 Other disorders of teeth and supporting structures	0.014	0.986	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.013	0.987	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.012	0.988	0.000
E06 Thyroiditis	0.011	0.989	0.000
O62 Abnormalities of forces of labour	0.011	0.989	0.000
O62.3 Precipitate labour	0.011	0.989	0.000
E07.8 Other specified disorders of thyroid	0.011	0.989	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.010	0.989	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.010	0.989	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.010	0.989	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.010	0.989	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.010	0.989	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.010	0.989	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.010	0.989	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.010	0.989	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.011	0.989	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.010	0.990	0.000
E07.1 Dyshormogenetic goitre	0.010	0.990	0.000
E07.0 Hypersecretion of calcitonin	0.010	0.990	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.010	0.990	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.010	0.990	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.010	0.990	0.000
O60-O75 Complications of labour and delivery	0.010	0.990	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.010	0.990	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.010	0.990	0.000
O62.1 Secondary uterine inertia	0.009	0.990	0.000
N20.0 Calculus of kidney	0.000	0.991	0.009
O72.0 Third-stage haemorrhage	0.009	0.991	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.009	0.991	0.000
O62.9 Abnormality of forces of labour, unspecified	0.009	0.991	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.009	0.991	0.000
O72 Postpartum haemorrhage	0.009	0.991	0.000
O62.2 Other uterine inertia	0.009	0.991	0.000
E06.9 Thyroiditis, unspecified	0.008	0.991	0.000
E07.9 Disorder of thyroid, unspecified	0.008	0.992	0.000
E06.4 Drug-induced thyroiditis	0.008	0.992	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.008	0.992	0.000
E06.0 Acute thyroiditis	0.008	0.992	0.000
E06.1 Subacute thyroiditis	0.008	0.992	0.000
O62.8 Other abnormalities of forces of labour	0.008	0.992	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.008	0.992	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.008	0.992	0.000
D68.9 Coagulation defect, unspecified	0.008	0.992	0.000
S22.2 Fracture of sternum	0.000	0.992	0.008
O75.8 Other specified complications of labour and delivery	0.008	0.992	0.000
O63 Long labour	0.008	0.992	0.000
N72 Inflammatory disease of cervix uteri	0.008	0.992	0.000
O74 Complications of anaesthesia during labour and delivery	0.008	0.992	0.000
E06.5 Other chronic thyroiditis	0.007	0.992	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.992	0.008
O71 Other obstetric trauma	0.008	0.992	0.000
O64.5 Obstructed labour due to compound presentation	0.007	0.992	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.008	0.992	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.007	0.993	0.000
D68 Other coagulation defects	0.007	0.993	0.000
O60 Preterm delivery	0.007	0.993	0.000
O62.0 Primary inadequate contractions	0.007	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.007	0.993	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.007	0.993	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.007	0.993	0.000
O64.4 Obstructed labour due to shoulder presentation	0.007	0.993	0.000
O75.0 Maternal distress during labour and delivery	0.007	0.993	0.000
D68.6 Other Thrombophilia	0.007	0.993	0.000
O64.2 Obstructed labour due to face presentation	0.007	0.993	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.007	0.993	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.007	0.993	0.000
O69.3 Labour and delivery complicated by short cord	0.007	0.993	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.007	0.993	0.000
N20 Calculus of kidney and ureter	0.000	0.993	0.007
I10-I15 Hypertensive diseases	0.007	0.993	0.000
O75.3 Other infection during labour	0.007	0.993	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.993	0.000
O63.1 Prolonged second stage (of labour)	0.007	0.993	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.007	0.993	0.000
O64.3 Obstructed labour due to brow presentation	0.006	0.993	0.000
O73 Retained placenta and membranes, without haemorrhage	0.007	0.993	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.993	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.993	0.007
O72.3 Postpartum coagulation defects	0.006	0.994	0.000
O75.4 Other complications of obstetric surgery and procedures	0.006	0.994	0.000
O75.1 Shock during or following labour and delivery	0.006	0.994	0.000
O71.8 Other specified obstetric trauma	0.006	0.994	0.000
I11 Hypertensive heart disease	0.006	0.994	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.006	0.994	0.000
O71.3 Obstetric laceration of cervix	0.006	0.994	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.994	0.000
E06.3 Autoimmune thyroiditis	0.006	0.994	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.006	0.994	0.000
O63.9 Long labour, unspecified	0.006	0.994	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.006	0.994	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.006	0.994	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.006	0.994	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.994	0.006
D68.1 Hereditary factor XI deficiency	0.006	0.994	0.000
S22.21 Fracture of sternum (open)	0.000	0.994	0.006
Z34.8 Supervision of other normal pregnancy	0.000	0.994	0.006
O61 Failed induction of labour	0.006	0.994	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.006	0.994	0.000
N23 Unspecified renal colic	0.000	0.994	0.006
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.006	0.994	0.000
O71.5 Other obstetric injury to pelvic organs	0.006	0.994	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.006	0.994	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.006	0.994	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.006	0.994	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.006	0.994	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.006	0.994	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.006	0.994	0.000
O66 Other obstructed labour	0.006	0.994	0.000
O71.2 Postpartum inversion of uterus	0.006	0.994	0.000
O71.1 Rupture of uterus during labour	0.006	0.994	0.000
O71.0 Rupture of uterus before onset of labour	0.006	0.994	0.000
D68.8 Other specified coagulation defects	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O75.9 Complication of labour and delivery, unspecified	0.006	0.994	0.000
O71.7 Obstetric haematoma of pelvis	0.006	0.994	0.000
O71.4 Obstetric high vaginal laceration alone	0.006	0.994	0.000
D68.5 Primary Thrombophilia	0.006	0.994	0.000
O60.3 Preterm delivery without spontaneous labour	0.005	0.994	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.994	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.994	0.000
O60.0 Preterm labour without delivery	0.005	0.994	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.994	0.006
I13 Hypertensive heart and renal disease	0.005	0.994	0.000
D68.4 Acquired coagulation factor deficiency	0.005	0.994	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.005	0.994	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
N20-N23 Urolithiasis	0.000	0.995	0.005
O64.8 Obstructed labour due to other malposition and malpresentation	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.005	0.995	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.005	0.995	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.005	0.995	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.005	0.995	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.005	0.995	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.005	0.995	0.000
O65.0 Obstructed labour due to deformed pelvis	0.005	0.995	0.000
O63.0 Prolonged first stage (of labour)	0.005	0.995	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.005	0.995	0.000
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
O61.1 Failed instrumental induction of labour	0.005	0.995	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.005	0.995	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.005	0.995	0.000
K81 Cholecystitis	0.005	0.995	0.000
O64.1 Obstructed labour due to breech presentation	0.005	0.995	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O66.9 Obstructed labour, unspecified	0.005	0.995	0.000
O71.9 Obstetric trauma, unspecified	0.005	0.995	0.000
D68.2 Hereditary deficiency of other clotting factors	0.005	0.995	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.004	0.995	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O61.8 Other failed induction of labour	0.004	0.995	0.000
O66.8 Other specified obstructed labour	0.004	0.995	0.000
I15 Secondary hypertension	0.004	0.996	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.004	0.996	0.000
O66.1 Obstructed labour due to locked twins	0.004	0.996	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.004	0.996	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.000	0.996	0.004
Z03.1 Observation for suspected malignant neoplasm	0.000	0.996	0.004
K42.0 Umbilical hernia with obstruction, without gangrene	0.004	0.996	0.000
O67.8 Other intrapartum haemorrhage	0.004	0.996	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.004	0.996	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.004	0.996	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.996	0.004
B34.9 Viral infection, unspecified	0.004	0.996	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.996	0.004
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.004	0.996	0.000
O72.1 Other immediate postpartum haemorrhage	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.996	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.004	0.996	0.000
I15.9 Seconday hypertension, unspecified	0.004	0.996	0.000
I15.2 Hypertension secondary to endocrine disorders	0.004	0.996	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.996	0.004
O61.0 Failed medical induction of labour	0.003	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.003	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.996	0.000
N20.9 Urinary calculus, unspecified	0.000	0.996	0.003
O61.9 Failed induction of labour, unspecified	0.003	0.996	0.000
O42 Premature rupture of membranes	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.003
U89.8 Agent resistant to other single specified antibiotic	0.000	0.996	0.004
K81.8 Other cholecystitis	0.003	0.996	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
I15.0 Renovascular hypertension	0.003	0.997	0.000
Z99.1 Dependence on respirator	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
N21 Calculus of lower urinary tract	0.000	0.997	0.003
O42.2 Premature rupture of membranes, labour delayed by therapy	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.000	0.997	0.003
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.997	0.003
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.997	0.003
I15.8 Other secondary hypertension	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.003
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.997	0.000
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.997	0.003
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.002	0.997	0.001
E05.4 Thyrotoxicosis factitia	0.002	0.997	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.997	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.997	0.003
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.003
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
N21.1 Calculus in urethra	0.000	0.997	0.003
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
B24 Unspecified human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
T93.1 Sequelae of fracture of femur	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
E11.9 Without complications	0.000	0.997	0.003
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.997	0.003
E13.9 Without complications	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.000	0.997	0.003
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.997	0.002
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
N21.8 Other lower urinary tract calculus	0.000	0.997	0.002
S22.5 Flail chest	0.000	0.997	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.997	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.002
O97 Death from sequelae of direct obstetric causes	0.002	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.997	0.000
O95 Obstetric death of unspecified cause	0.002	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.997	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.997	0.002
K82 Other diseases of gallbladder	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
S22.3 Fracture of rib	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
E04 Other non-toxic goitre	0.001	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
N03.9 Unspecified	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
B35.3 Tinea pedis	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
I42.8 Other cardiomyopathies	0.002	0.998	0.000
M19.1 Posttraumatic arthrosis of other joints	0.000	0.998	0.002
K81.1 Chronic cholecystitis	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
O70 Perineal laceration during delivery	0.002	0.998	0.000
F01 Vascular dementia	0.002	0.998	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.998	0.001
S22.51 Flail chest (open)	0.000	0.998	0.002
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.000	0.998	0.002
K82.0 Obstruction of gallbladder	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.002
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.998	0.002
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
C44.5 Skin of trunk	0.002	0.998	0.000
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.001	0.998	0.001
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.998	0.002
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.998	0.002
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.998	0.002
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.002
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.000	0.998	0.002
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
G82.0 Flaccid paraplegia	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
H81.0 Meniere's disease	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
K82.3 Fistula of gallbladder	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
M79.58 Residual foreign body in soft tissue (Other)	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
D09.0 Bladder	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
M79.5 Residual foreign body in soft tissue	0.000	0.998	0.002
Z29.9 Prophylactic measure, unspecified	0.000	0.998	0.002
M79.56 Residual foreign body in soft tissue (Lower leg)	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.002
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.001	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
K82.9 Disease of gallbladder, unspecified	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.000	0.998	0.002
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.998	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
R50.8 Other specified fever	0.000	0.998	0.002
I12 Hypertensive renal disease	0.002	0.998	0.000
B34 Viral infection of unspecified site	0.002	0.998	0.000
N20.1 Calculus of ureter	0.000	0.998	0.002
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.001
B34.4 Papovirus infection, unspecified	0.001	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.001	0.998	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.000	0.998	0.001
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.000	0.998	0.001
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.000	0.998	0.001
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.000	0.998	0.001
K72.1 Chronic hepatic failure	0.001	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.998	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.000	0.998	0.001
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
X63.0 Home	0.001	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.001	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.001	0.998	0.000
O90.5 Postpartum thyroiditis	0.001	0.998	0.000
O90.4 Postpartum acute renal failure	0.001	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.001	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.001	0.998	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.001	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.001
Z59.0 Homelessness	0.001	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.001	0.998	0.000
F06.7 Mild cognitive disorder	0.001	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.001	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations