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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs885948
log Bayes Factor = 119.244
Chromosome 6   position 31,140,532  (GRCh37) Explore rs885948 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.034 0.966
L40.0 Psoriasis vulgaris
0.000 0.040 0.960
E14.9 Without complications
0.000 0.044 0.956
E10.3 With ophthalmic complications
0.000 0.053 0.947
E11.4 With neurological complications
0.000 0.061 0.939
E13 Other specified diabetes mellitus
0.000 0.083 0.917
E11.0 With coma
0.000 0.117 0.883
E05.9 Thyrotoxicosis, unspecified
0.000 0.133 0.867
E13.9 Without complications
0.000 0.138 0.862
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.138 0.862
E11.1 With ketoacidosis
0.000 0.140 0.860
L40.1 Generalised pustular psoriasis
0.000 0.141 0.859
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.143 0.857
E10.2 With renal complications
0.000 0.143 0.857
L40.8 Other psoriasis
0.000 0.149 0.851
E10.8 With unspecified complications
0.000 0.174 0.826
K90 Intestinal malabsorption
0.000 0.195 0.805
E14.2 Withrenal complications
0.000 0.204 0.796
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.204 0.796
E00-E07 Disorders of thyroid gland
0.000 0.209 0.791
E14.8 With unspecified complications
0.000 0.216 0.784
E10.7 With multiple complications
0.000 0.223 0.777
L40.4 Guttate psoriasis
0.000 0.223 0.777
E14.5 With peripheral circulatory complications
0.000 0.234 0.766
E11.5 With peripheral circulatory complications
0.000 0.236 0.763
E11.2 With renal complications
0.000 0.238 0.762
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.245 0.755
E14.6 With other specified complications
0.000 0.264 0.736
E10.0 With coma
0.000 0.269 0.731
E14.0 With coma
0.000 0.270 0.730
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.273 0.727
E16 Other disorders of pancreatic internal secretion
0.000 0.275 0.725
E14.4 With neurological complications
0.000 0.278 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.285 0.715
E10.1 With ketoacidosis
0.000 0.285 0.715
E14.1 With ketoacidosis
0.000 0.294 0.705
E16.2 Hypoglycaemia, unspecified
0.000 0.304 0.696
E11.7 With multiple complications
0.000 0.325 0.675
E11.8 With unspecified complications
0.000 0.328 0.672
L40.3 Pustulosis palmaris et plantaris
0.000 0.341 0.659
E13.8 With unspecified complications
0.000 0.342 0.658
E13.7 With multiple complications
0.000 0.342 0.658
E13.6 With other specified complications
0.000 0.342 0.658
E13.5 With peripheral circulatory complications
0.000 0.342 0.658
E13.4 With neurological complications
0.000 0.342 0.658
E13.2 With renal complications
0.000 0.342 0.658
E13.1 With ketoacidosis
0.000 0.342 0.658
E13.0 With coma
0.000 0.342 0.658
K90.9 Intestinal malabsorption, unspecified
0.000 0.352 0.648
E13.3 With ophthalmic complications
0.000 0.361 0.638
K90.8 Other intestinal malabsorption
0.000 0.374 0.626
E10.6 With other specified complications
0.000 0.379 0.620
E05.5 Thyroid crisis or storm
0.000 0.382 0.618
E05.4 Thyrotoxicosis factitia
0.000 0.382 0.618
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.382 0.618
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.382 0.618
K90.3 Pancreatic steatorrhoea
0.000 0.422 0.577
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.422 0.577
K90.1 Tropical sprue
0.000 0.422 0.577
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.433 0.567
E00 Congenital iodine-deficiency syndrome
0.000 0.433 0.567
E16.1 Other hypoglycaemia
0.000 0.445 0.555
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.451 0.549
E15 Nondiabetic hypoglycaemic coma
0.000 0.459 0.541
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.480 0.520
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.480 0.520
E16.4 Abnormal secretion of gastrin
0.000 0.480 0.520
E16.3 Increased secretion of glucagon
0.000 0.480 0.520
E05.8 Other thyrotoxicosis
0.000 0.480 0.520
E10.4 With neurological complications
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E40-E46 Malnutrition
0.000 0.517 0.483
E03 Other hypothyroidism
0.000 0.521 0.479
E11.6 With other specified complications
0.000 0.532 0.468
E10.5 With peripheral circulatory complications
0.000 0.553 0.446
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.585 0.415
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.592 0.407
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.593 0.407
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.593 0.407
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.593 0.407
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.593 0.407
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.593 0.407
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.593 0.407
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.593 0.407
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.593 0.407
E07 Other disorders of thyroid
0.000 0.601 0.399
E03.8 Other specified hypothyroidism
0.000 0.615 0.384
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.642 0.357
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.653 0.346
E45 Retarded development following protein-energy malnutrition
0.000 0.653 0.346
E43 Unspecified severe protein-energy malnutrition
0.000 0.653 0.346
E42 Marasmic kwashiorkor
0.000 0.653 0.346
E41 Nutritional marasmus
0.000 0.653 0.346
E40 Kwashiorkor
0.000 0.653 0.346
E03.5 Myxoedema coma
0.000 0.657 0.343
E03.4 Atrophy of thyroid (acquired)
0.000 0.657 0.343
E03.3 Postinfectious hypothyroidism
0.000 0.657 0.343
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.667 0.333
E03.1 Congenital hypothyroidism without goitre
0.000 0.682 0.318
E20-E35 Disorders of other endocrine glands
0.000 0.683 0.317
E07.8 Other specified disorders of thyroid
0.000 0.698 0.302
E07.1 Dyshormogenetic goitre
0.000 0.714 0.286
E07.0 Hypersecretion of calcitonin
0.000 0.714 0.286
E50-E64 Other nutritional deficiencies
0.000 0.722 0.278
E70-E90 Metabolic disorders
0.000 0.723 0.277
E24 Cushing's syndrome
0.000 0.725 0.275
E25 Adrenogenital disorders
0.000 0.733 0.267
E65-E68 Obesity and other hyperalimentation
0.000 0.737 0.263
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.738 0.262
E46 Unspecified protein-energy malnutrition
0.000 0.741 0.259
E88 Other metabolic disorders
0.000 0.749 0.251
E78.5 Hyperlipidaemia, unspecified
0.000 0.749 0.251
E24.0 Pituitary-dependent Cushing's disease
0.000 0.750 0.250
L40-L45 Papulosquamous disorders
0.000 0.751 0.249
E44.1 Mild protein-energy malnutrition
0.000 0.751 0.248
E44.0 Moderate protein-energy malnutrition
0.000 0.751 0.248
E06 Thyroiditis
0.000 0.756 0.243
E78.2 Mixed hyperlipidaemia
0.000 0.756 0.244
E23 Hypofunction and other disorders of pituitary gland
0.000 0.758 0.242
E24.2 Drug-induced Cushing's syndrome
0.000 0.765 0.235
E79 Disorders of purine and pyrimidine metabolism
0.000 0.768 0.232
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.769 0.231
E34 Other endocrine disorders
0.000 0.769 0.231
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.769 0.231
E31 Polyglandular dysfunction
0.000 0.770 0.230
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.773 0.227
E32 Diseases of thymus
0.000 0.773 0.227
E30 Disorders of puberty, not elsewhere classified
0.000 0.773 0.227
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.777 0.223
E78.1 Pure hyperglyceridaemia
0.000 0.778 0.222
E55 Vitamin D deficiency
0.000 0.783 0.216
E23.7 Disorder of pituitary gland, unspecified
0.000 0.790 0.210
E11.3 With ophthalmic complications
0.000 0.794 0.206
E88.8 Other specified metabolic disorders
0.000 0.795 0.205
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.795 0.205
E20 Hypoparathyroidism
0.000 0.797 0.203
E78.8 Other disorders of lipoprotein metabolism
0.000 0.798 0.202
E56 Other vitamin deficiencies
0.000 0.800 0.200
E74 Other disorders of carbohydrate metabolism
0.000 0.800 0.200
E70 Disorders of aromatic amino-acid metabolism
0.000 0.800 0.200
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.800 0.200
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.801 0.199
E63 Other nutritional deficiencies
0.000 0.801 0.199
E50 Vitamin A deficiency
0.000 0.801 0.199
E60 Dietary zinc deficiency
0.000 0.801 0.199
E59 Dietary selenium deficiency
0.000 0.801 0.199
E52 Niacin deficiency [pellagra]
0.000 0.801 0.199
E77 Disorders of glycoprotein metabolism
0.000 0.801 0.199
E76 Disorders of glycosaminoglycan metabolism
0.000 0.801 0.199
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.801 0.199
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.801 0.199
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.803 0.197
E24.3 Ectopic ACTH syndrome
0.000 0.803 0.197
E24.1 Nelson's syndrome
0.000 0.803 0.197
E78.4 Other hyperlipidaemia
0.000 0.803 0.197
E85 Amyloidosis
0.000 0.805 0.195
E72 Other disorders of amino-acid metabolism
0.000 0.805 0.195
E29 Testicular dysfunction
0.000 0.807 0.192
E25.9 Adrenogenital disorder, unspecified
0.000 0.808 0.191
E25.8 Other adrenogenital disorders
0.000 0.808 0.191
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.810 0.190
E23.6 Other disorders of pituitary gland
0.000 0.811 0.189
E67 Other hyperalimentation
0.000 0.811 0.189
E68 Sequelae of hyperalimentation
0.000 0.811 0.189
E88.9 Metabolic disorder, unspecified
0.000 0.812 0.188
E88.2 Lipomatosis, not elsewhere classified
0.000 0.813 0.187
E24.8 Other Cushing's syndrome
0.000 0.815 0.184
E78.3 Hyperchylomicronaemia
0.000 0.815 0.184
L42 Pityriasis rosea
0.000 0.816 0.184
E34.8 Other specified endocrine disorders
0.000 0.816 0.184
E58 Dietary calcium deficiency
0.000 0.817 0.183
E51 Thiamine deficiency
0.000 0.818 0.182
E22 Hyperfunction of pituitary gland
0.000 0.818 0.182
E34.3 Short stature, not elsewhere classified
0.000 0.819 0.181
L44 Other papulosquamous disorders
0.000 0.821 0.179
L41 Parapsoriasis
0.000 0.821 0.179
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.821 0.179
E80.1 Porphyria cutanea tarda
0.000 0.821 0.179
E80.4 Gilbert's syndrome
0.000 0.822 0.178
E80.2 Other porphyria
0.000 0.823 0.177
E78.6 Lipoprotein deficiency
0.000 0.823 0.177
E06.4 Drug-induced thyroiditis
0.000 0.825 0.175
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.825 0.175
E06.0 Acute thyroiditis
0.000 0.825 0.175
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.826 0.174
E23.1 Drug-induced hypopituitarism
0.000 0.826 0.174
E88.3 Tumour lysis syndrome
0.000 0.826 0.173
E55.9 Vitamin D deficiency, unspecified
0.000 0.827 0.173
E84 Cystic fibrosis
0.000 0.827 0.172
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.828 0.172
E80.6 Other disorders of bilirubin metabolism
0.000 0.831 0.169
E54 Ascorbic acid deficiency
0.000 0.831 0.169
E06.5 Other chronic thyroiditis
0.000 0.831 0.169
E31.0 Autoimmune polyglandular failure
0.000 0.832 0.167
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.833 0.166
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.833 0.166
E79.1 Lesch-Nyhan syndrome
0.000 0.833 0.166
E34.5 Androgen resistance syndrome
0.000 0.834 0.166
E34.4 Constitutional tall stature
0.000 0.834 0.166
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.834 0.166
E34.1 Other hypersecretion of intestinal hormones
0.000 0.834 0.166
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.834 0.166
E80.5 Crigler-Najjar syndrome
0.000 0.834 0.166
E80.3 Defects of catalase and peroxydase
0.000 0.834 0.166
E80.0 Hereditary erythropoietic porphyria
0.000 0.834 0.166
E28 Ovarian dysfunction
0.000 0.835 0.165
E31.9 Polyglandular dysfunction, unspecified
0.000 0.835 0.165
E31.8 Other polyglandular dysfunction
0.000 0.835 0.165
E31.1 Polyglandular hyperfunction
0.000 0.835 0.165
E34.9 Endocrine disorder, unspecified
0.000 0.837 0.163
E30.9 Disorder of puberty, unspecified
0.000 0.837 0.163
E30.8 Other disorders of puberty
0.000 0.837 0.163
E30.1 Precocious puberty
0.000 0.837 0.163
E30.0 Delayed puberty
0.000 0.837 0.163
E32.9 Disease of thymus, unspecified
0.000 0.837 0.163
E32.8 Other diseases of thymus
0.000 0.837 0.163
E32.1 Abscess of thymus
0.000 0.837 0.163
E32.0 Persistent hyperplasia of thymus
0.000 0.837 0.163
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.837 0.163
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.837 0.163
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.837 0.163
E21.2 Other hyperparathyroidism
0.000 0.841 0.159
E26 Hyperaldosteronism
0.000 0.843 0.156
E21.3 Hyperparathyroidism, unspecified
0.000 0.844 0.156
E55.0 Rickets, active
0.000 0.845 0.155
E21.4 Other specified disorders of parathyroid gland
0.000 0.845 0.155
E61 Deficiency of other nutrient elements
0.000 0.845 0.155
E23.0 Hypopituitarism
0.000 0.846 0.154
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.847 0.153
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.847 0.153
E85.4 Organ-limited amyloidosis
0.000 0.849 0.151
E85.9 Amyloidosis, unspecified
0.000 0.852 0.148
E06.1 Subacute thyroiditis
0.001 0.852 0.147
E27 Other disorders of adrenal gland
0.000 0.853 0.146
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.854 0.146
E20.8 Other hypoparathyroidism
0.000 0.854 0.145
E20.1 Pseudohypoparathyroidism
0.000 0.854 0.145
E20.0 Idiopathic hypoparathyroidism
0.000 0.854 0.145
E56.1 Deficiency of vitamin K
0.000 0.855 0.145
E70.3 Albinism
0.000 0.855 0.145
E56.9 Vitamin deficiency, unspecified
0.000 0.856 0.144
E56.8 Deficiency of other vitamins
0.000 0.856 0.144
E56.0 Deficiency of vitamin E
0.000 0.856 0.144
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.856 0.144
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.856 0.144
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.856 0.144
E74.2 Disorders of galactose metabolism
0.000 0.856 0.144
E74.1 Disorders of fructose metabolism
0.000 0.856 0.144
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.856 0.143
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.856 0.143
E70.2 Disorders of tyrosine metabolism
0.000 0.856 0.143
E70.1 Other hyperphenylalaninaemias
0.000 0.856 0.143
E70.0 Classical phenylketonuria
0.000 0.856 0.143
E50.9 Vitamin A deficiency, unspecified
0.000 0.857 0.143
E50.8 Other manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.857 0.143
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.857 0.143
E50.5 Vitamin A deficiency with night blindness
0.000 0.857 0.143
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.857 0.143
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.857 0.143
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.857 0.143
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.857 0.143
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.857 0.143
E63.9 Nutritional deficiency, unspecified
0.000 0.857 0.143
E63.8 Other specified nutritional deficiencies
0.000 0.857 0.143
E63.1 Imbalance of constituents of food intake
0.000 0.857 0.143
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.857 0.143
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.857 0.143
E64.8 Sequelae of other nutritional deficiencies
0.000 0.857 0.143
E64.3 Sequelae of rickets
0.000 0.857 0.143
E64.2 Sequelae of vitamin C deficiency
0.000 0.857 0.143
E64.1 Sequelae of vitamin A deficiency
0.000 0.857 0.143
E64.0 Sequelae of protein-energy malnutrition
0.000 0.857 0.143
E71.3 Disorders of fatty-acid metabolism
0.000 0.857 0.143
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.857 0.143
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.857 0.143
E71.0 Maple-syrup-urine disease
0.000 0.857 0.143
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.857 0.143
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.857 0.143
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.857 0.143
E76.2 Other mucopolysaccharidoses
0.000 0.857 0.143
E76.1 Mucopolysaccharidosis, type II
0.000 0.857 0.143
E76.0 Mucopolysaccharidosis, type I
0.000 0.857 0.143
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.857 0.143
E77.8 Other disorders of glycoprotein metabolism
0.000 0.857 0.143
E77.1 Defects in glycoprotein degradation
0.000 0.857 0.143
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.857 0.143
E85.8 Other amyloidosis
0.000 0.858 0.142
E73 Lactose intolerance
0.000 0.858 0.141
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.860 0.140
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.860 0.140
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.860 0.140
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.860 0.140
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.860 0.140
E72.5 Disorders of glycine metabolism
0.000 0.860 0.140
E72.4 Disorders of ornithine metabolism
0.000 0.860 0.140
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.860 0.140
E72.2 Disorders of urea cycle metabolism
0.000 0.860 0.140
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.860 0.140
E29.9 Testicular dysfunction, unspecified
0.000 0.862 0.138
E29.8 Other testicular dysfunction
0.000 0.862 0.138
E29.0 Testicular hyperfunction
0.000 0.862 0.138
E72.0 Disorders of amino-acid transport
0.000 0.863 0.137
E75.6 Lipid storage disorder, unspecified
0.000 0.863 0.136
E75.5 Other lipid storage disorders
0.000 0.863 0.136
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.863 0.136
E75.3 Sphingolipidosis, unspecified
0.000 0.863 0.136
E75.1 Other gangliosidosis
0.000 0.863 0.136
E75.0 GM2 gangliosidosis
0.000 0.863 0.136
E67.8 Other specified hyperalimentation
0.000 0.864 0.135
E67.3 Hypervitaminosis D
0.000 0.864 0.135
E67.2 Megavitamin-B6 syndrome
0.000 0.864 0.135
E67.1 Hypercarotenaemia
0.000 0.864 0.135
E67.0 Hypervitaminosis A
0.000 0.864 0.135
E74.0 Glycogen storage disease
0.000 0.866 0.134
E06.9 Thyroiditis, unspecified
0.001 0.867 0.132
E22.1 Hyperprolactinaemia
0.000 0.869 0.131
E51.9 Thiamine deficiency, unspecified
0.000 0.869 0.130
E51.8 Other manifestations of thiamine deficiency
0.000 0.869 0.130
E51.1 Beriberi
0.000 0.869 0.130
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.869 0.131
E22.8 Other hyperfunction of pituitary gland
0.000 0.869 0.131
L41.9 Parapsoriasis, unspecified
0.000 0.871 0.128
L41.8 Other parapsoriasis
0.000 0.871 0.128
L41.5 Retiform parapsoriasis
0.000 0.871 0.128
L41.4 Large plaque parapsoriasis
0.000 0.871 0.128
L41.3 Small plaque parapsoriasis
0.000 0.871 0.128
L41.2 Lymphomatoid papulosis
0.000 0.871 0.128
L41.1 Pityriasis lichenoides chronica
0.000 0.871 0.128
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.871 0.128
L44.9 Papulosquamous disorder, unspecified
0.000 0.871 0.128
L44.8 Other specified papulosquamous disorders
0.000 0.871 0.128
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.871 0.128
L44.3 Lichen ruber moniliformis
0.000 0.871 0.128
L44.2 Lichen striatus
0.000 0.871 0.128
L44.1 Lichen nitidus
0.000 0.871 0.128
L44.0 Pityriasis rubra pilaris
0.000 0.871 0.128
E75.2 Other sphingolipidosis
0.000 0.872 0.128
E23.2 Diabetes insipidus
0.000 0.873 0.127
E53 Deficiency of other B group vitamins
0.000 0.873 0.126
E34.0 Carcinoid syndrome
0.000 0.874 0.126
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.874 0.126
E24.9 Cushing's syndrome, unspecified
0.000 0.875 0.125
E84.8 Cystic fibrosis with other manifestations
0.000 0.876 0.124
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.876 0.124
E20.9 Hypoparathyroidism, unspecified
0.000 0.879 0.121
E28.9 Ovarian dysfunction, unspecified
0.000 0.881 0.119
E28.8 Other ovarian dysfunction
0.000 0.881 0.119
E28.1 Androgen excess
0.000 0.881 0.119
E28.0 Oestrogen excess
0.000 0.881 0.119
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.883 0.117
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.883 0.117
E51.2 Wernicke's encephalopathy
0.000 0.886 0.113
E84.9 Cystic fibrosis, unspecified
0.000 0.887 0.113
M07.3 Other psoriatic arthropathies
0.000 0.887 0.113
E26.8 Other hyperaldosteronism
0.000 0.887 0.112
E26.1 Secondary hyperaldosteronism
0.000 0.887 0.112
E27.1 Primary adrenocortical insufficiency
0.000 0.888 0.111
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.889 0.111
E61.9 Deficiency of nutrient element, unspecified
0.000 0.889 0.111
E61.8 Deficiency of other specified nutrient elements
0.000 0.889 0.111
E61.7 Deficiency of multiple nutrient elements
0.000 0.889 0.111
E61.6 Vanadium deficiency
0.000 0.889 0.111
E61.5 Molybdenum deficiency
0.000 0.889 0.111
E61.4 Chromium deficiency
0.000 0.889 0.111
E61.3 Manganese deficiency
0.000 0.889 0.111
E61.0 Copper deficiency
0.000 0.889 0.111
E28.3 Primary ovarian failure
0.000 0.891 0.109
E85.3 Secondary systemic amyloidosis
0.000 0.892 0.107
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.893 0.107
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.894 0.106
E27.5 Adrenomedullary hyperfunction
0.000 0.895 0.105
E27.0 Other adrenocortical overactivity
0.000 0.895 0.105
E22.0 Acromegaly and pituitary gigantism
0.000 0.896 0.104
E61.2 Magnesium deficiency
0.000 0.896 0.104
E29.1 Testicular hypofunction
0.000 0.896 0.103
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.898 0.102
E73.8 Other lactose intolerance
0.000 0.898 0.101
E73.1 Secondary lactase deficiency
0.000 0.898 0.101
E73.0 Congenital lactase deficiency
0.000 0.898 0.101
E65 Localised adiposity
0.001 0.902 0.098
E27.9 Disorder of adrenal gland, unspecified
0.000 0.905 0.095
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.905 0.095
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.905 0.095
E26.9 Hyperaldosteronism, unspecified
0.000 0.905 0.094
E66 Obesity
0.000 0.909 0.091
E53.1 Pyridoxine deficiency
0.000 0.909 0.091
E53.0 Riboflavin deficiency
0.000 0.909 0.091
K51.9 Ulcerative colitis, unspecified
0.089 0.911 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.914 0.086
L43 Lichen planus
0.000 0.915 0.085
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.916 0.084
K51 Ulcerative colitis
0.083 0.917 0.000
E06.3 Autoimmune thyroiditis
0.000 0.917 0.082
E89.3 Postprocedural hypopituitarism
0.000 0.917 0.082
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.918 0.082
M07.38 Other psoriatic arthropathies (Other)
0.000 0.919 0.081
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.919 0.081
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.919 0.081
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.919 0.081
E27.8 Other specified disorders of adrenal gland
0.000 0.920 0.080
E61.1 Iron deficiency
0.000 0.921 0.079
K51.2 Ulcerative (chronic) proctitis
0.078 0.922 0.000
K51.4 Pseudopolyposis of colon
0.077 0.923 0.000
E26.0 Primary hyperaldosteronism
0.001 0.925 0.075
E28.2 Polycystic ovarian syndrome
0.000 0.925 0.075
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.926 0.074
E89.1 Postprocedural hypoinsulinaemia
0.000 0.926 0.074
K51.3 Ulcerative (chronic) rectosigmoiditis
0.074 0.926 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.926 0.074
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.927 0.073
E07.9 Disorder of thyroid, unspecified
0.000 0.928 0.072
E89.5 Postprocedural testicular hypofunction
0.000 0.928 0.072
G56.0 Carpal tunnel syndrome
0.000 0.931 0.069
E89.4 Postprocedural ovarian failure
0.000 0.933 0.067
E27.2 Addisonian crisis
0.000 0.934 0.066
E66.1 Drug-induced obesity
0.000 0.934 0.066
K51.5 Mucosal proctocolitis
0.066 0.934 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.935 0.064
K90-K93 Other diseases of the digestive system
0.000 0.936 0.064
E53.8 Deficiency of other specified B group vitamins
0.000 0.936 0.064
K51.1 Ulcerative (chronic) ileocolitis
0.063 0.937 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.937 0.062
L43.3 Subacute (active) lichen planus
0.000 0.939 0.061
L43.2 Lichenoid drug reaction
0.000 0.939 0.061
L43.1 Bullous lichen planus
0.000 0.939 0.061
L43.0 Hypertrophic lichen planus
0.000 0.939 0.061
E89.2 Postprocedural hypoparathyroidism
0.000 0.941 0.059
E66.0 Obesity due to excess calories
0.000 0.943 0.057
M07 Psoriatic and enteropathic arthropathies
0.000 0.948 0.052
E21.0 Primary hyperparathyroidism
0.000 0.948 0.052
E04 Other non-toxic goitre
0.001 0.952 0.047
K51.8 Other ulcerative colitis
0.047 0.953 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.954 0.046
E73.9 Lactose intolerance, unspecified
0.001 0.955 0.044
M07.5 Arthropathy in ulcerative colitis
0.000 0.963 0.037
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.963 0.037
M07.2 Psoriatic spondylitis
0.000 0.963 0.037
M07.1 Arthritis mutilans
0.000 0.963 0.037
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.963 0.037
C71 Malignant neoplasm of brain
0.037 0.963 0.000
M07.6 Other enteropathic arthropathies
0.000 0.963 0.037
R31 Unspecified haematuria
0.036 0.964 0.000
C71.3 Parietal lobe
0.036 0.964 0.000
C71.2 Temporal lobe
0.035 0.965 0.000
C71.9 Brain, unspecified
0.035 0.965 0.000
E04.8 Other specified non-toxic goitre
0.001 0.965 0.034
C71.0 Cerebrum, except lobes and ventricles
0.034 0.966 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.966 0.033
K93.1 Megacolon in Chagas' disease
0.000 0.966 0.033
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.966 0.033
K91.4 Colostomy and enterostomy malfunction
0.033 0.967 0.000
L43.8 Other lichen planus
0.001 0.967 0.032
G56 Mononeuropathies of upper limb
0.000 0.967 0.033
L43.9 Lichen planus, unspecified
0.000 0.968 0.031
E04.0 Non-toxic diffuse goitre
0.001 0.969 0.030
K51.0 Ulcerative (chronic) enterocolitis
0.029 0.971 0.000
C71.4 Occipital lobe
0.028 0.972 0.000
E86 Volume depletion
0.000 0.972 0.028
C71.6 Cerebellum
0.028 0.972 0.000
C71.5 Cerebral ventricle
0.028 0.972 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.973 0.027
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.973 0.027
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.973 0.027
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.973 0.027
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.973 0.027
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.973 0.027
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.973 0.027
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.973 0.027
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.973 0.027
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.973 0.027
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.973 0.027
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.973 0.027
M07.18 Arthritis mutilans (Other)
0.000 0.973 0.027
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.973 0.027
M07.16 Arthritis mutilans (Lower leg)
0.000 0.973 0.027
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.973 0.027
M07.14 Arthritis mutilans (Hand)
0.000 0.973 0.027
M07.13 Arthritis mutilans (Forearm)
0.000 0.973 0.027

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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