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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs886205
log Bayes Factor = 6.08279
Chromosome 12   position 112,204,427  (GRCh37) Explore rs886205 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.001 0.999
I21 Acute myocardial infarction
0.000 0.001 0.999
I25 Chronic ischaemic heart disease
0.000 0.002 0.998
I20-I25 Ischaemic heart diseases
0.000 0.002 0.998
E03.9 Hypothyroidism, unspecified
0.000 0.004 0.996
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.008 0.992
I25.1 Atherosclerotic heart disease
0.000 0.012 0.988
I22 Subsequent myocardial infarction
0.000 0.054 0.946
I25.5 Ischaemic cardiomyopathy
0.000 0.060 0.940
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.084 0.916
I21.9 Acute myocardial infarction, unspecified
0.000 0.100 0.900
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.171 0.829
I25.4 Coronary artery aneurysm
0.000 0.179 0.821
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.222 0.778
I25.2 Old myocardial infarction
0.000 0.258 0.742
I24 Other acute ischaemic heart diseases
0.000 0.261 0.739
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.716
I25.6 Silent myocardial ischaemia
0.000 0.284 0.716
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.291 0.709
I23 Certain current complications following acute myocardial infarction
0.000 0.307 0.693
I24.8 Other forms of acute ischaemic heart disease
0.000 0.333 0.667
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.337 0.663
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.344 0.655
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.360 0.640
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.377 0.623
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.379 0.621
I22.8 Subsequent myocardial infarction of other sites
0.000 0.381 0.619
Z95.0 Presence of cardiac pacemaker
0.000 0.404 0.596
I25.3 Aneurysm of heart
0.000 0.404 0.596
Z95.2 Presence of prosthetic heart valve
0.000 0.432 0.568
Z95.1 Presence of aortocoronary bypass graft
0.000 0.441 0.559
I24.1 Dressler's syndrome
0.000 0.446 0.554
Z95.4 Presence of other heart-valve replacement
0.000 0.449 0.551
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.468 0.532
E03 Other hypothyroidism
0.000 0.468 0.532
Z95.3 Presence of xenogenic heart valve
0.000 0.501 0.499
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.503 0.497
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.503 0.497
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.503 0.497
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.503 0.497
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.503 0.497
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.503 0.497
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.503 0.497
I21.4 Acute subendocardial myocardial infarction
0.000 0.506 0.494
I23.8 Other current complications following acute myocardial infarction
0.000 0.525 0.475
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.567 0.433
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.570 0.430
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.586 0.414
E03.5 Myxoedema coma
0.000 0.619 0.381
E03.4 Atrophy of thyroid (acquired)
0.000 0.619 0.381
E03.3 Postinfectious hypothyroidism
0.000 0.619 0.381
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.619 0.381
E03.8 Other specified hypothyroidism
0.000 0.630 0.370
E03.1 Congenital hypothyroidism without goitre
0.000 0.645 0.354
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.799 0.201
I20 Angina pectoris
0.000 0.803 0.197
I20.8 Other forms of angina pectoris
0.000 0.821 0.179
E00-E07 Disorders of thyroid gland
0.000 0.871 0.129
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.875 0.124
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.886 0.114
E05.9 Thyrotoxicosis, unspecified
0.000 0.891 0.109
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.907 0.093
E00 Congenital iodine-deficiency syndrome
0.000 0.907 0.093
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.908 0.092
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.909 0.091
E06 Thyroiditis
0.000 0.911 0.089
E05.5 Thyroid crisis or storm
0.000 0.918 0.082
E05.4 Thyrotoxicosis factitia
0.000 0.918 0.082
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.918 0.082
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.918 0.082
E05.8 Other thyrotoxicosis
0.000 0.925 0.075
E07 Other disorders of thyroid
0.000 0.931 0.069
E06.3 Autoimmune thyroiditis
0.000 0.932 0.068
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.933 0.066
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.933 0.066
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.933 0.066
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.933 0.066
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.933 0.066
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.933 0.066
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.933 0.066
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.933 0.066
E06.4 Drug-induced thyroiditis
0.000 0.936 0.064
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.936 0.064
E06.1 Subacute thyroiditis
0.000 0.936 0.064
E06.0 Acute thyroiditis
0.000 0.936 0.064
E06.9 Thyroiditis, unspecified
0.000 0.936 0.063
E06.5 Other chronic thyroiditis
0.000 0.943 0.057
E07.1 Dyshormogenetic goitre
0.000 0.950 0.050
E07.0 Hypersecretion of calcitonin
0.000 0.950 0.050
E07.8 Other specified disorders of thyroid
0.000 0.955 0.045
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.956 0.043
R25.1 Tremor, unspecified
0.036 0.964 0.000
R25 Abnormal involuntary movements
0.035 0.965 0.000
J34.2 Deviated nasal septum
0.035 0.965 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.965 0.035
R25.2 Cramp and spasm
0.034 0.966 0.000
I20.1 Angina pectoris with documented spasm
0.002 0.967 0.031
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.967 0.033
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.031 0.969 0.000
S72.00 Fracture of neck of femur (closed)
0.000 0.971 0.029
R26 Abnormalities of gait and mobility
0.028 0.972 0.000
S72.0 Fracture of neck of femur
0.000 0.973 0.027
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.027 0.973 0.000
R26.3 Immobility
0.027 0.973 0.000
S72 Fracture of femur
0.000 0.974 0.026
S72.30 Fracture of shaft of femur (closed)
0.000 0.974 0.026
S72.3 Fracture of shaft of femur
0.000 0.974 0.026
I20.9 Angina pectoris, unspecified
0.000 0.974 0.026
S72.1 Pertrochanteric fracture
0.000 0.974 0.026
R25.0 Abnormal head movements
0.025 0.974 0.000
S72.10 Pertrochanteric fracture (closed)
0.000 0.975 0.025
R25.8 Other and unspecified abnormal involuntary movements
0.025 0.975 0.000
Chapter IX Diseases of the circulatory system
0.000 0.975 0.025
R27 Other lack of coordination
0.025 0.975 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.024 0.976 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.024 0.976 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.977 0.023
I99 Other and unspecified disorders of circulatory system
0.000 0.978 0.022
I10 Essential (primary) hypertension
0.000 0.978 0.022
R29.0 Tetany
0.022 0.978 0.000
R25.3 Fasciculation
0.022 0.978 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.979 0.021
R27.8 Other and unspecified lack of coordination
0.021 0.979 0.000
I10-I15 Hypertensive diseases
0.000 0.979 0.021
R29.2 Abnormal reflex
0.021 0.979 0.000
R26.1 Paralytic gait
0.020 0.980 0.000
S72.4 Fracture of lower end of femur
0.000 0.980 0.020
S72.01 Fracture of neck of femur (open)
0.000 0.980 0.020
S72.8 Fractures of other parts of femur
0.000 0.980 0.020
R29.4 Clicking hip
0.019 0.980 0.000
R29.3 Abnormal posture
0.019 0.980 0.000
R29.1 Meningismus
0.019 0.980 0.000
S72.7 Multiple fractures of femur
0.000 0.981 0.019
S72.31 Fracture of shaft of femur (open)
0.000 0.981 0.019
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.981 0.019
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.981 0.019
S72.11 Pertrochanteric fracture (open)
0.000 0.981 0.018
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.981 0.019
R26.0 Ataxic gait
0.018 0.982 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.982 0.018
I00-I02 Acute rheumatic fever
0.000 0.982 0.018
S72.9 Fracture of femur, part unspecified
0.000 0.982 0.017
R27.0 Ataxia, unspecified
0.017 0.983 0.000
I49.9 Cardiac arrhythmia, unspecified
0.000 0.983 0.017
R26.2 Difficulty in walking, not elsewhere classified
0.016 0.984 0.000
S72.40 Fracture of lower end of femur (closed)
0.000 0.984 0.016
S72.2 Subtrochanteric fracture
0.000 0.984 0.016
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.984 0.015
I97.0 Postcardiotomy syndrome
0.000 0.984 0.015
I13 Hypertensive heart and renal disease
0.000 0.985 0.015
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.985 0.015
I49.3 Ventricular premature depolarisation
0.000 0.985 0.015
E04 Other non-toxic goitre
0.000 0.985 0.015
S72.80 Fractures of other parts of femur (closed)
0.000 0.985 0.015
S72.41 Fracture of lower end of femur (open)
0.000 0.985 0.015
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.985 0.015
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.986 0.014
R29.6 Tendency to fall, not elsewhere classified
0.014 0.986 0.000
S72.81 Fractures of other parts of femur (open)
0.000 0.986 0.014
I49 Other cardiac arrhythmias
0.000 0.986 0.014
S72.71 Multiple fractures of femur (open)
0.000 0.986 0.014
S72.70 Multiple fractures of femur (closed)
0.000 0.986 0.014
I15 Secondary hypertension
0.000 0.986 0.014
I86.4 Gastric varices
0.000 0.986 0.014
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.000 0.986 0.013
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.000 0.986 0.013
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.000 0.986 0.013
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.000 0.986 0.013
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.000 0.986 0.013
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.000 0.986 0.013
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.000 0.986 0.013
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.000 0.986 0.013
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.000 0.986 0.013
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.986 0.013
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.986 0.013
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.986 0.013
I98.0 Cardiovascular syphilis
0.000 0.986 0.013
I02 Rheumatic chorea
0.000 0.987 0.013
I01 Rheumatic fever with heart involvement
0.000 0.987 0.013
I00 Rheumatic fever without mention of heart involvement
0.000 0.987 0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.987 0.013
I85.0 Oesophageal varices with bleeding
0.000 0.987 0.013
I85 Oesophageal varices
0.000 0.987 0.013
S72.91 Fracture of femur, part unspecified (open)
0.000 0.987 0.013
I86 Varicose veins of other sites
0.000 0.988 0.012
I80 Phlebitis and thrombophlebitis
0.000 0.988 0.012
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.988 0.012
T93.2 Sequelae of other fractures of lower limb
0.012 0.988 0.000
S72.21 Subtrochanteric fracture (open)
0.000 0.988 0.011
S72.90 Fracture of femur, part unspecified (closed)
0.000 0.989 0.011
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.989 0.011
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.989 0.011
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.989 0.011
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.989 0.011
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.989 0.011
I30-I52 Other forms of heart disease
0.000 0.989 0.011
I50 Heart failure
0.000 0.989 0.011
E04.8 Other specified non-toxic goitre
0.000 0.989 0.011
I49.0 Ventricular fibrillation and flutter
0.000 0.989 0.011
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.989 0.011
I49.4 Other and unspecified premature depolarisation
0.000 0.989 0.011
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.989 0.011
I50.1 Left ventricular failure
0.000 0.989 0.011
I11 Hypertensive heart disease
0.000 0.989 0.010
I35 Nonrheumatic aortic valve disorders
0.000 0.989 0.011
I49.2 Junctional premature depolarisation
0.000 0.990 0.010
I35.0 Aortic (valve) stenosis
0.000 0.990 0.010
E04.0 Non-toxic diffuse goitre
0.000 0.990 0.010
I15.8 Other secondary hypertension
0.000 0.990 0.010
I15.2 Hypertension secondary to endocrine disorders
0.000 0.990 0.010
I15.0 Renovascular hypertension
0.000 0.990 0.010
I47.2 Ventricular tachycardia
0.000 0.990 0.010
I49.5 Sick sinus syndrome
0.000 0.990 0.010
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.990 0.010
I85.9 Oesophageal varices without bleeding
0.000 0.990 0.010
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.990 0.009
I01.8 Other acute rheumatic heart disease
0.000 0.990 0.009
I01.2 Acute rheumatic myocarditis
0.000 0.990 0.009
I01.1 Acute rheumatic endocarditis
0.000 0.990 0.009
I01.0 Acute rheumatic pericarditis
0.000 0.990 0.009
I02.9 Rheumatic chorea without heart involvement
0.000 0.990 0.009
I02.0 Rheumatic chorea with heart involvement
0.000 0.990 0.009
I15.9 Seconday hypertension, unspecified
0.000 0.990 0.009
I50.0 Congestive heart failure
0.000 0.990 0.010
I47 Paroxysmal tachycardia
0.000 0.990 0.010
I86.2 Pelvic varices
0.000 0.991 0.009
I86.3 Vulval varices
0.000 0.991 0.009
I86.0 Sublingual varices
0.000 0.991 0.009
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.991 0.009
I15.1 Hypertension secondary to other renal disorders
0.000 0.991 0.009
I05-I09 Chronic rheumatic heart diseases
0.000 0.991 0.009
E27 Other disorders of adrenal gland
0.000 0.991 0.009
M35.0 Sicca syndrome [Sjogren]
0.000 0.991 0.009
I42 Cardiomyopathy
0.000 0.991 0.009
E20-E35 Disorders of other endocrine glands
0.000 0.991 0.009
I36 Nonrheumatic tricuspid valve disorders
0.000 0.991 0.008
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.991 0.009
I88 Nonspecific lymphadenitis
0.000 0.992 0.008
I33 Acute and subacute endocarditis
0.000 0.992 0.008
I52 Other heart disorders in diseases classified elsewhere
0.000 0.992 0.008
I48 Atrial fibrillation and flutter
0.000 0.992 0.008
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.992 0.008
I41 Myocarditis in diseases classified elsewhere
0.000 0.992 0.008
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.992 0.008
I32 Pericarditis in diseases classified elsewhere
0.000 0.992 0.008
S72.20 Subtrochanteric fracture (closed)
0.000 0.992 0.008
E27.1 Primary adrenocortical insufficiency
0.000 0.992 0.008
M72 Fibroblastic disorders
0.000 0.992 0.008
E10.3 With ophthalmic complications
0.000 0.992 0.008
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.992 0.008
I50.9 Heart failure, unspecified
0.000 0.992 0.008
I37 Pulmonary valve disorders
0.000 0.992 0.008
E27.8 Other specified disorders of adrenal gland
0.000 0.992 0.008
I26 Pulmonary embolism
0.000 0.992 0.008
K74.3 Primary biliary cirrhosis
0.000 0.992 0.008
I82 Other venous embolism and thrombosis
0.000 0.992 0.008
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.992 0.008
I35.9 Aortic valve disorder, unspecified
0.000 0.992 0.008
I42.0 Dilated cardiomyopathy
0.000 0.992 0.008
I12 Hypertensive renal disease
0.000 0.992 0.007
I83 Varicose veins of lower extremities
0.000 0.992 0.008
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.993 0.007
I42.9 Cardiomyopathy, unspecified
0.000 0.993 0.007
I28 Other diseases of pulmonary vessels
0.000 0.993 0.007
I87 Other disorders of veins
0.000 0.993 0.007
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.993 0.007
I40 Acute myocarditis
0.000 0.993 0.007
I86.1 Scrotal varices
0.000 0.993 0.007
E34 Other endocrine disorders
0.000 0.993 0.007
I47.0 Reentry ventricular arrhythmia
0.000 0.993 0.007
E10 Insulin-dependent diabetes mellitus
0.000 0.993 0.007
J34 Other disorders of nose and nasal sinuses
0.007 0.993 0.000
E28 Ovarian dysfunction
0.000 0.993 0.007
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.993 0.007
J32.0 Chronic maxillary sinusitis
0.000 0.993 0.007
E27.9 Disorder of adrenal gland, unspecified
0.000 0.993 0.007
E23 Hypofunction and other disorders of pituitary gland
0.000 0.993 0.007
E27.2 Addisonian crisis
0.000 0.993 0.007
K74 Fibrosis and cirrhosis of liver
0.000 0.993 0.007
K74.5 Biliary cirrhosis, unspecified
0.000 0.993 0.007
I07 Rheumatic tricuspid valve diseases
0.000 0.993 0.007
I06 Rheumatic aortic valve diseases
0.000 0.993 0.007
S70-S79 Injuries to the hip and thigh
0.000 0.993 0.007
E27.5 Adrenomedullary hyperfunction
0.000 0.993 0.007
E27.0 Other adrenocortical overactivity
0.000 0.993 0.007
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.993 0.007
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.993 0.006
I20.0 Unstable angina
0.000 0.993 0.007
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.993 0.007
I42.5 Other restrictive cardiomyopathy
0.000 0.993 0.006
I42.4 Endocardial fibroelastosis
0.000 0.993 0.006
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.993 0.006
I86.8 Varicose veins of other specified sites
0.000 0.993 0.006
J34.3 Hypertrophy of nasal turbinates
0.007 0.993 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.993 0.007
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.993 0.007
S22.40 Multiple fractures of ribs (closed)
0.007 0.993 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.993 0.007
E21.3 Hyperparathyroidism, unspecified
0.000 0.994 0.006
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.994 0.006
E32 Diseases of thymus
0.000 0.994 0.006
E31 Polyglandular dysfunction
0.000 0.994 0.006
E30 Disorders of puberty, not elsewhere classified
0.000 0.994 0.006
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.994 0.006
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.994 0.006
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.994 0.006
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.994 0.006
I49.1 Atrial premature depolarisation
0.000 0.994 0.006
I38 Endocarditis, valve unspecified
0.000 0.994 0.006
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.994 0.006
I87.8 Other specified disorders of veins
0.000 0.994 0.006
I33.9 Acute endocarditis, unspecified
0.000 0.994 0.006
I88.8 Other nonspecific lymphadenitis
0.000 0.994 0.006
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.994 0.006
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.994 0.006
I33.0 Acute and subacute infective endocarditis
0.000 0.994 0.006
E25 Adrenogenital disorders
0.000 0.994 0.006
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.994 0.006
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.994 0.006
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.994 0.006
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.994 0.006
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.994 0.006
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.994 0.006
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.994 0.006
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.994 0.006
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.994 0.006
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.994 0.006
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.994 0.006
I48.4 Atypical atrial flutter
0.000 0.994 0.006
I48.3 Typical atrial flutter
0.000 0.994 0.006
I48.2 Chronic atrial fibrillation
0.000 0.994 0.006
I48.1 Persistent atrial fibrillation
0.000 0.994 0.006
I48.0 Paroxysmal atrial fibrillation
0.000 0.994 0.006
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.994 0.006
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.994 0.006
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.994 0.006
I30 Acute pericarditis
0.000 0.994 0.006
I42.6 Alcoholic cardiomyopathy
0.000 0.994 0.006
E34.9 Endocrine disorder, unspecified
0.000 0.994 0.006
M72.9 Fibroblastic disorder, unspecified
0.000 0.994 0.006
M72.8 Other fibroblastic disorders
0.000 0.994 0.006
M72.6 Necrotizing fasciitis
0.000 0.994 0.006
M72.5 Fasciitis, not elsewhere classified
0.000 0.994 0.006
M72.4 Pseudosarcomatous fibromatosis
0.000 0.994 0.006
M72.3 Nodular fasciitis
0.000 0.994 0.006
M72.2 Plantar fascial fibromatosis
0.000 0.994 0.006
M72.1 Knuckle pads
0.000 0.994 0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.994 0.006
K74.6 Other and unspecified cirrhosis of liver
0.000 0.994 0.006
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.994 0.006
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.994 0.006
E10.9 Without complications
0.000 0.994 0.006
I37.9 Pulmonary valve disorder, unspecified
0.000 0.994 0.006
I37.8 Other pulmonary valve disorders
0.000 0.994 0.006
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.994 0.006
I37.0 Pulmonary valve stenosis
0.000 0.994 0.006
E20 Hypoparathyroidism
0.000 0.994 0.006
E40-E46 Malnutrition
0.000 0.994 0.006
D73.0 Hyposplenism
0.000 0.994 0.006
I82.3 Embolism and thrombosis of renal vein
0.000 0.994 0.006
I82.1 Thrombophlebitis migrans
0.000 0.994 0.006
I82.0 Budd-Chiari syndrome
0.000 0.994 0.006
E23.2 Diabetes insipidus
0.000 0.994 0.006
I35.8 Other aortic valve disorders
0.000 0.994 0.006
E04.9 Non-toxic goitre, unspecified
0.000 0.994 0.006
E10.8 With unspecified complications
0.000 0.994 0.006
E10-E14 Diabetes mellitus
0.000 0.994 0.006
I37.1 Pulmonary valve insufficiency
0.000 0.994 0.006
E10.6 With other specified complications
0.000 0.994 0.006
E10.5 With peripheral circulatory complications
0.000 0.994 0.006
E10.0 With coma
0.000 0.994 0.006
E22 Hyperfunction of pituitary gland
0.000 0.994 0.006
E34.0 Carcinoid syndrome
0.000 0.994 0.006
M20.4 Other hammer toe(s) (acquired)
0.006 0.994 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.994 0.006
I42.2 Other hypertrophic cardiomyopathy
0.000 0.994 0.006
I09 Other rheumatic heart diseases
0.000 0.994 0.005
I81 Portal vein thrombosis
0.000 0.994 0.005
E28.3 Primary ovarian failure
0.000 0.994 0.005
E28.2 Polycystic ovarian syndrome
0.000 0.994 0.006
E24 Cushing's syndrome
0.000 0.994 0.005
E50-E64 Other nutritional deficiencies
0.000 0.994 0.006
M20.0 Deformity of finger(s)
0.006 0.994 0.000
S22.4 Multiple fractures of ribs
0.006 0.994 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.006 0.994 0.000
R16.1 Splenomegaly, not elsewhere classified
0.000 0.994 0.006
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.994 0.005
I28.1 Aneurysm of pulmonary artery
0.000 0.994 0.005
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.994 0.005
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.006 0.994 0.000
I87.9 Disorder of vein, unspecified
0.000 0.994 0.005
I87.0 Postphlebitic syndrome
0.000 0.994 0.005
E21.4 Other specified disorders of parathyroid gland
0.000 0.995 0.005
E21.2 Other hyperparathyroidism
0.000 0.995 0.005
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.995 0.005
I40.9 Acute myocarditis, unspecified
0.000 0.995 0.005
I40.8 Other acute myocarditis
0.000 0.995 0.005
I40.1 Isolated myocarditis
0.000 0.995 0.005
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.995 0.005
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.005 0.995 0.000
E26 Hyperaldosteronism
0.000 0.995 0.005
E34.5 Androgen resistance syndrome
0.000 0.995 0.005
E34.4 Constitutional tall stature
0.000 0.995 0.005
E34.3 Short stature, not elsewhere classified
0.000 0.995 0.005
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.995 0.005
E34.1 Other hypersecretion of intestinal hormones
0.000 0.995 0.005
E21.0 Primary hyperparathyroidism
0.000 0.995 0.005
M20.6 Acquired deformity of toe(s), unspecified
0.005 0.995 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.995 0.005
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.000 0.995 0.005
E23.7 Disorder of pituitary gland, unspecified
0.000 0.995 0.005
E28.9 Ovarian dysfunction, unspecified
0.000 0.995 0.005
E28.8 Other ovarian dysfunction
0.000 0.995 0.005
E28.1 Androgen excess
0.000 0.995 0.005
E28.0 Oestrogen excess
0.000 0.995 0.005
I82.2 Embolism and thrombosis of vena cava
0.000 0.995 0.005
J32 Chronic sinusitis
0.000 0.995 0.005
E10.4 With neurological complications
0.000 0.995 0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.995 0.005
E23.1 Drug-induced hypopituitarism
0.000 0.995 0.005
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.995 0.005
K74.4 Secondary biliary cirrhosis
0.000 0.995 0.005
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.995 0.005
K74.1 Hepatic sclerosis
0.000 0.995 0.005
S71 Open wound of hip and thigh
0.000 0.995 0.005
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.995 0.005
I06.8 Other rheumatic aortic valve diseases
0.000 0.995 0.005
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.995 0.005
I06.1 Rheumatic aortic insufficiency
0.000 0.995 0.005
I06.0 Rheumatic aortic stenosis
0.000 0.995 0.005
I42.8 Other cardiomyopathies
0.000 0.995 0.005
I07.9 Tricuspid valve disease, unspecified
0.000 0.995 0.005
I07.8 Other tricuspid valve diseases
0.000 0.995 0.005
I07.2 Tricuspid stenosis with insufficiency
0.000 0.995 0.005
I07.0 Tricuspid stenosis
0.000 0.995 0.005
S22.0 Fracture of thoracic vertebra
0.005 0.995 0.000
E23.0 Hypopituitarism
0.000 0.995 0.005
D72.8 Other specified disorders of white blood cells
0.000 0.995 0.005
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.995 0.005
S78 Traumatic amputation of hip and thigh
0.000 0.995 0.005
S77 Crushing injury of hip and thigh
0.000 0.995 0.005
S75 Injury of blood vessels at hip and thigh level
0.000 0.995 0.005
S74 Injury of nerves at hip and thigh level
0.000 0.995 0.005
I07.1 Tricuspid insufficiency
0.000 0.995 0.005
K74.0 Hepatic fibrosis
0.000 0.995 0.005
I05 Rheumatic mitral valve diseases
0.000 0.995 0.005
M20 Acquired deformities of fingers and toes
0.005 0.995 0.000
E34.8 Other specified endocrine disorders
0.000 0.995 0.005
T80.2 Infections following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.005 0.995 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.995 0.005
E30.8 Other disorders of puberty
0.000 0.995 0.005
E30.1 Precocious puberty
0.000 0.995 0.005
E30.0 Delayed puberty
0.000 0.995 0.005
E31.9 Polyglandular dysfunction, unspecified
0.000 0.995 0.005
E31.8 Other polyglandular dysfunction
0.000 0.995 0.005
E31.1 Polyglandular hyperfunction
0.000 0.995 0.005
E31.0 Autoimmune polyglandular failure
0.000 0.995 0.005
E32.9 Disease of thymus, unspecified
0.000 0.995 0.005
E32.8 Other diseases of thymus
0.000 0.995 0.005
E32.1 Abscess of thymus
0.000 0.995 0.005
E32.0 Persistent hyperplasia of thymus
0.000 0.995 0.005
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.995 0.005
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.995 0.005
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.995 0.005
I28.8 Other specified diseases of pulmonary vessels
0.000 0.995 0.004
I35.1 Aortic (valve) insufficiency
0.000 0.995 0.005
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.995 0.004
J32.2 Chronic ethmoidal sinusitis
0.000 0.995 0.005
E29 Testicular dysfunction
0.000 0.995 0.005
D75 Other diseases of blood and blood-forming organs
0.000 0.995 0.005
D72 Other disorders of white blood cells
0.000 0.995 0.005
S76 Injury of muscle and tendon at hip and thigh level
0.000 0.995 0.005
E23.6 Other disorders of pituitary gland
0.000 0.995 0.005
E10.2 With renal complications
0.000 0.995 0.005
E25.9 Adrenogenital disorder, unspecified
0.000 0.995 0.005
E25.8 Other adrenogenital disorders
0.000 0.995 0.005
J34.0 Abscess, furuncle and carbuncle of nose
0.005 0.995 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.995 0.005
I30.8 Other forms of acute pericarditis
0.000 0.995 0.004
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.995 0.004
T80 Complications following infusion, transfusion and therapeutic injection
0.005 0.995 0.000
I30.1 Infective pericarditis
0.000 0.995 0.004
D73 Diseases of spleen
0.000 0.995 0.005
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.995 0.005
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.995 0.005
M72.19 Knuckle pads (Site unspecified)
0.000 0.995 0.004
M72.18 Knuckle pads-Other
0.000 0.995 0.004
M72.17 Knuckle pads (Ankle and foot)
0.000 0.995 0.004
M72.16 Knuckle pads-Lower Leg
0.000 0.995 0.004
M72.15 Knuckle pads-Pelvic/Thigh
0.000 0.995 0.004
M72.14 Knuckle pads (Hand)
0.000 0.995 0.004
M72.13 Knuckle pads-Forearm
0.000 0.995 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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