TreeWAS – Variant ID: rs906628

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.878	0.122
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.875	0.125
T84.0 Mechanical complication of internal joint prosthesis	0.866	0.134
T85 Complications of other internal prosthetic devices, implants and grafts	0.860	0.140
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.858	0.142
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.839	0.161
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.826	0.174
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.812	0.188
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.771	0.229
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.755	0.245
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.744	0.256
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.743	0.257
Chapter VII Diseases of the eye and adnexa	0.742	0.258
Chapter XX External causes of morbidity and mortality	0.738	0.262
# Top node	0.734	0.266
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.730	0.270
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.725	0.275
H53-H54 Visual disturbances and blindness	0.725	0.275
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.720	0.280
H53 Visual disturbances	0.715	0.285
T83.0 Mechanical complication of urinary (indwelling) catheter	0.712	0.288
H52 Disorders of refraction and accommodation	0.711	0.289
W00-W19 Falls	0.705	0.295
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.704	0.296
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.702	0.298
Y86 Sequelae of other accidents	0.701	0.299
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.699	0.301
H49 Paralytic strabismus	0.698	0.302
T88 Other complications of surgical and medical care, not elsewhere classified	0.695	0.305
T91 Sequelae of injuries of neck and trunk	0.689	0.311
S10-S19 Injuries to the neck	0.684	0.316
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.681	0.319
S60-S69 Injuries to the wrist and hand	0.680	0.320
H50 Other strabismus	0.677	0.323
S90-S99 Injuries to the ankle and foot	0.673	0.327
S50-S59 Injuries to the elbow and forearm	0.672	0.328
H53.1 Subjective visual disturbances	0.670	0.330
Chapter VI Diseases of the nervous system	0.669	0.331
H18 Other disorders of cornea	0.667	0.333
T83.1 Mechanical complication of other urinary devices and implants	0.664	0.336
T15-T19 Effects of foreign body entering through natural orifice	0.657	0.343
T20-T25 Burns and corrosions of external body surface, specified by site	0.656	0.344
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.651	0.349
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.650	0.350
T84.3 Mechanical complication of other bone devices, implants and grafts	0.648	0.352
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.647	0.353
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.647	0.353
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.645	0.355
T79-T79 Certain early complications of trauma	0.645	0.355
T84.2 Mechanical complication of internal fixation device of other bones	0.641	0.359
H53.2 Diplopia	0.641	0.359
H49.1 Fourth [trochlear] nerve palsy	0.637	0.363
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.636	0.364
Q20-Q28 Congenital malformations of the circulatory system	0.635	0.365
S80-S89 Injuries to the knee and lower leg	0.634	0.366
V20-V29 Motorcycle rider injured in transport accident	0.634	0.366
G20-G26 Extrapyramidal and movement disorders	0.633	0.367
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.633	0.367
Y88 Sequelae of surgical and medical care as external cause	0.633	0.367
H52.3 Anisometropia and aniseikonia	0.629	0.371
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.625	0.375
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.625	0.375
H52.2 Astigmatism	0.623	0.377
T80 Complications following infusion, transfusion and therapeutic injection	0.620	0.380
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.618	0.382
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.617	0.383
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.617	0.383
T83.2 Mechanical complication of graft of urinary organ	0.615	0.385
T85.2 Mechanical complication of intraocular lens	0.613	0.387
W03 Other fall on same level due to collision with, or pushing by, another person	0.612	0.388
T91.3 Sequelae of injury of spinal cord	0.610	0.390
H55-H59 Other disorders of eye and adnexa	0.609	0.391
T87 Complications peculiar to reattachment and amputation	0.609	0.391
Q80-Q89 Other congenital malformations	0.609	0.391
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.607	0.393
H53.4 Visual field defects	0.605	0.395
H52.1 Myopia	0.604	0.396
T83.3 Mechanical complication of intra-uterine contraceptive device	0.601	0.399
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.600	0.400
H49.2 Sixth [abducent] nerve palsy	0.599	0.401
V95-V97 Air and space transport accidents	0.598	0.401
W19 Unspecified fall	0.598	0.402
H50.0 Convergent concomitant strabismus	0.597	0.403
Y84.6 Urinary catheterisation	0.596	0.404
H18.4 Corneal degeneration	0.595	0.405
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.593	0.407
T33-T35 Frostbite	0.592	0.408
T26-T28 Burns and corrosions confined to eye and internal organs	0.592	0.408
T84.1 Mechanical complication of internal fixation device of bones of limb	0.590	0.410
T91.2 Sequelae of other fracture of thorax and pelvis	0.589	0.411
T00-T07 Injuries involving multiple body regions	0.586	0.414
G35-G37 Demyelinating diseases of the central nervous system	0.586	0.414
Q60-Q64 Congenital malformations of the urinary system	0.586	0.414
G20 Parkinson's disease	0.585	0.415
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.581	0.419
S40-S49 Injuries to the shoulder and upper arm	0.579	0.421
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.578	0.422
T91.8 Sequelae of other specified injuries of neck and trunk	0.576	0.424
T88.5 Other complications of anaesthesia	0.574	0.426
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.573	0.427
W75-W84 Other accidental threats to breathing	0.572	0.428
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.572	0.428
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.571	0.429
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.570	0.430
Q24 Other congenital malformations of heart	0.567	0.433
S70-S79 Injuries to the hip and thigh	0.566	0.434
V40-V49 Car occupant injured in transport accident	0.565	0.435
H53.0 Amblyopia ex anopsia	0.562	0.438
G70-G73 Diseases of myoneural junction and muscle	0.561	0.439
S60 Superficial injury of wrist and hand	0.561	0.439
Y84.0 Cardiac catheterisation	0.560	0.440
W17 Other fall from one level to another	0.559	0.441
Q66 Congenital deformities of feet	0.559	0.441
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.558	0.442
T98 Sequelae of other and unspecified effects of external causes	0.558	0.442
G24 Dystonia	0.555	0.445
W11 Fall on and from ladder	0.552	0.448
H50.1 Divergent concomitant strabismus	0.551	0.449
W06 Fall involving bed	0.550	0.450
D37-D48 Neoplasms of uncertain or unknown behaviour	0.550	0.450
T85.4 Mechanical complication of breast prosthesis and implant	0.548	0.451
S19 Other and unspecified injuries of neck	0.548	0.452
S90 Superficial injury of ankle and foot	0.548	0.452
W01 Fall on same level from slipping, tripping and stumbling	0.548	0.452
H20 Iridocyclitis	0.547	0.453
H18.8 Other specified disorders of cornea	0.547	0.453
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.546	0.454
H46-H48 Disorders of optic nerve and visual pathways	0.546	0.454
W03.9 Unspecified place	0.545	0.455
Chapter II Neoplasms	0.545	0.455
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.544	0.456
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.543	0.457
S54 Injury of nerves at forearm level	0.543	0.457
X50-X57 Overexertion, travel and privation	0.543	0.457
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.543	0.457
Chapter V Mental and behavioural disorders	0.542	0.458
T92 Sequelae of injuries of upper limb	0.542	0.458
W18 Other fall on same level	0.542	0.458
H18.5 Hereditary corneal dystrophies	0.541	0.459
Chapter XXII Codes for special purposes	0.541	0.459
S66 Injury of muscle and tendon at wrist and hand level	0.541	0.459
Q00-Q07 Congenital malformations of the nervous system	0.540	0.460
H16 Keratitis	0.539	0.461
S80 Superficial injury of lower leg	0.538	0.462
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.536	0.464
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.535	0.465
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.535	0.465
Q38-Q45 Other congenital malformations of the digestive system	0.534	0.466
H43-H45 Disorders of vitreous body and globe	0.533	0.467
H52.7 Disorder of refraction, unspecified	0.533	0.467
H51 Other disorders of binocular movement	0.532	0.467
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.532	0.468
Y00-Y09 Assault	0.531	0.469
H10-H13 Disorders of conjunctiva	0.530	0.470
Y35-Y36 Legal intervention and operations of war	0.529	0.471
Y10-Y34 Event of undetermined intent	0.529	0.471
X85-X99 Assault	0.529	0.471
X30-X39 Exposure to forces of nature	0.529	0.471
X10-X19 Contact with heat and hot substances	0.529	0.471
X00-X09 Exposure to smoke, fire and flames	0.529	0.471
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.529	0.471
W65-W74 Accidental drowning and submersion	0.529	0.471
V98-V99 Other and unspecified transport accidents	0.529	0.471
V90-V94 Water transport accidents	0.529	0.471
V70-V79 Bus occupant injured in transport accident	0.529	0.471
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.529	0.471
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.529	0.471
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.529	0.471
V01-V09 Pedestrian injured in transport accident	0.529	0.471
Q21 Congenital malformations of cardiac septa	0.529	0.471
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.528	0.472
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.528	0.472
W19.2 School, other institution and public administrative area	0.527	0.473
Chapter XVI Certain conditions originating in the perinatal period	0.526	0.474
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.526	0.474
T94 Sequelae of injuries involving multiple and unspecified body regions	0.526	0.474
T59 Toxic effect of other gases, fumes and vapours	0.525	0.475
T58 Toxic effect of carbon monoxide	0.525	0.475
S91 Open wound of ankle and foot	0.524	0.475
T18 Foreign body in alimentary tract	0.524	0.476
T95 Sequelae of burns, corrosions and frostbite	0.523	0.476
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.523	0.476
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.523	0.476
X58-X59 Accidental exposure to other and unspecified factors	0.523	0.477
H53.8 Other visual disturbances	0.523	0.477
S50 Superficial injury of forearm	0.523	0.477
V80-V89 Other land transport accidents	0.522	0.478
S40 Superficial injury of shoulder and upper arm	0.522	0.478
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.521	0.479
W50-W64 Exposure to animate mechanical forces	0.521	0.479
Q35-Q37 Cleft lip and cleft palate	0.520	0.480
Q30-Q34 Congenital malformations of the respiratory system	0.520	0.480
T90 Sequelae of injuries of head	0.520	0.480
G00-G09 Inflammatory diseases of the central nervous system	0.518	0.482
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.516	0.484
S51 Open wound of forearm	0.515	0.485
T79 Certain early complications of trauma, not elsewhere classified	0.515	0.485
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.515	0.485
H53.6 Night blindness	0.513	0.487
H53.5 Colour vision deficiencies	0.513	0.487
H53.3 Other disorders of binocular vision	0.513	0.487
Q24.8 Other specified congenital malformations of heart	0.512	0.488
W10 Fall on and from stairs and steps	0.511	0.488
H50.9 Strabismus, unspecified	0.511	0.489
V27 Motorcycle rider injured in collision with fixed or stationary object	0.511	0.489
S65 Injury of blood vessels at wrist and hand level	0.510	0.490
W19.4 Street and highway	0.510	0.490
H18.6 Keratoconus	0.510	0.490
H52.6 Other disorders of refraction	0.510	0.490
H52.5 Disorders of accommodation	0.510	0.490
H52.4 Presbyopia	0.510	0.490
S56 Injury of muscle and tendon at forearm level	0.509	0.491
H57 Other disorders of eye and adnexa	0.508	0.492
V28 Motorcycle rider injured in noncollision transport accident	0.508	0.492
S63.6 Sprain and strain of finger(s)	0.507	0.493
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.507	0.493
W16 Diving or jumping into water causing injury other than drowning or submersion	0.505	0.494
W15 Fall from cliff	0.505	0.494
W14 Fall from tree	0.505	0.494
W12 Fall on and from scaffolding	0.505	0.494
W09 Fall involving playground equipment	0.505	0.494
W05 Fall involving wheelchair	0.505	0.494
W04 Fall while being carried or supported by other persons	0.505	0.494
W00 Fall on same level involving ice and snow	0.505	0.494
Q50-Q56 Congenital malformations of genital organs	0.505	0.494
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.505	0.495
H17 Corneal scars and opacities	0.505	0.495
H15 Disorders of sclera	0.505	0.495
Y60-Y69 Misadventures to patients during surgical and medical care	0.504	0.496
Y84.8 Other medical procedures	0.503	0.497
Q65 Congenital deformities of hip	0.502	0.497
S83.2 Tear of meniscus, current	0.502	0.498
Y89 Sequelae of other external causes	0.502	0.498
S93.1 Dislocation of toe(s)	0.502	0.498
Q76 Congenital malformations of spine and bony thorax	0.501	0.499
H49.9 Paralytic strabismus, unspecified	0.501	0.499
H49.8 Other paralytic strabismus	0.501	0.499
H49.4 Progressive external ophthalmoplegia	0.501	0.499
H49.3 Total (external) ophthalmoplegia	0.501	0.499
V97 Other specified air transport accidents	0.499	0.501
T88.9 Complication of surgical and medical care, unspecified	0.498	0.501
T88.3 Malignant hyperthermia due to anaesthesis	0.498	0.501
T88.2 Shock due to anaesthesia	0.498	0.501
T88.1 Other complications following immunisation, not elsewhere classified	0.498	0.501
T88.0 Infection following immunisation	0.498	0.501
T88.7 Unspecified adverse effect of drug or medicament	0.497	0.502
T21 Burn and corrosion of trunk	0.497	0.503
S10 Superficial injury of neck	0.497	0.503
X20-X29 Contact with venomous animals and plants	0.496	0.503
G30-G32 Other degenerative diseases of the nervous system	0.496	0.504
S69 Other and unspecified injuries of wrist and hand	0.496	0.504
Q82 Other congenital malformations of skin	0.495	0.505
C51-C58 Malignant neoplasms of female genital organs	0.495	0.505
T91.9 Sequelae of unspecified injury of neck and trunk	0.494	0.506
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.494	0.506
T91.4 Sequelae of injury of intrathoracic organs	0.494	0.506
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.494	0.506
G80-G83 Cerebral palsy and other paralytic syndromes	0.494	0.506
G11 Hereditary ataxia	0.494	0.506
H49.0 Third [oculomotor] nerve palsy	0.492	0.508
H55 Nystagmus and other irregular eye movements	0.492	0.508
S68 Traumatic amputation of wrist and hand	0.492	0.508
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.491	0.509
G35 Multiple sclerosis	0.491	0.509
S17 Crushing injury of neck	0.490	0.510
S15 Injury of blood vessels at neck level	0.490	0.510
S14 Injury of nerves and spinal cord at neck level	0.490	0.510
S11 Open wound of neck	0.490	0.510
S18 Traumatic amputation at neck level	0.490	0.510
S16 Injury of muscle and tendon at neck level	0.490	0.510
S60.9 Superficial injury of wrist and hand, unspecified	0.490	0.510
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.490	0.510
T63 Toxic effect of contact with venomous animals	0.490	0.510
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.489	0.511
S12 Fracture of neck	0.488	0.512
T17 Foreign body in respiratory tract	0.487	0.513
H50.8 Other specified strabismus	0.486	0.514
H50.6 Mechanical strabismus	0.486	0.514
H50.5 Heterophoria	0.486	0.514
H50.4 Other and unspecified heterotropia	0.486	0.514
H50.3 Intermittent heterotropia	0.486	0.514
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.486	0.514
Q27 Other congenital malformations of peripheral vascular system	0.485	0.515
H54 Blindness and low vision	0.483	0.517
S98 Traumatic amputation of ankle and foot	0.483	0.517
S97 Crushing injury of ankle and foot	0.483	0.517
S96 Injury of muscle and tendon at ankle and foot level	0.483	0.517
S95 Injury of blood vessels at ankle and foot level	0.483	0.517
S94 Injury of nerves at ankle and foot level	0.483	0.517
D37.2 Small intestine	0.483	0.517
S59 Other and unspecified injuries of forearm	0.482	0.518
S58 Traumatic amputation of forearm	0.482	0.518
S57 Crushing injury of forearm	0.482	0.518
S55 Injury of blood vessels at forearm level	0.482	0.518
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.482	0.518
S67 Crushing injury of wrist and hand	0.482	0.518
H50.2 Vertical strabismus	0.481	0.519
G37 Other demyelinating diseases of central nervous system	0.481	0.519
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.481	0.519
X60-X84 Intentional self-harm	0.480	0.520
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.480	0.520
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.479	0.521
H18.7 Other corneal deformities	0.478	0.522
H18.3 Changes in corneal membranes	0.478	0.522
H18.2 Other corneal oedema	0.478	0.522
H18.1 Bullous keratopathy	0.478	0.522
H18.0 Corneal pigmentations and deposits	0.478	0.522
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.478	0.522
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.478	0.522
H53.9 Visual disturbance, unspecified	0.477	0.522
Q63 Other congenital malformations of kidney	0.476	0.524
D37.5 Rectum	0.476	0.524
W07 Fall involving chair	0.475	0.524
V10-V19 Pedal cyclist injured in transport accident	0.475	0.525
Q61 Cystic kidney disease	0.475	0.525
S31 Open wound of abdomen, lower back and pelvis	0.474	0.526
S37 Injury of urinary and pelvic organs	0.471	0.529
T19 Foreign body in genito-urinary tract	0.471	0.529
T15 Foreign body on external eye	0.471	0.529
T16 Foreign body in ear	0.471	0.529
T25 Burn and corrosion of ankle and foot	0.470	0.530
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.470	0.530
T23 Burn and corrosion of wrist and hand	0.470	0.530
Chapter VIII Diseases of the ear and mastoid process	0.470	0.530
F99-F99 Unspecified mental disorder	0.468	0.532
H18.9 Disorder of cornea, unspecified	0.467	0.533
Q78 Other osteochondrodysplasias	0.467	0.533
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.467	0.533
Q75 Other congenital malformations of skull and face bones	0.467	0.533
Q74 Other congenital malformations of limb(s)	0.467	0.533
Q73 Reduction defects of unspecified limb	0.467	0.533
Q72 Reduction defects of lower limb	0.467	0.533
Q71 Reduction defects of upper limb	0.467	0.533
Q70 Syndactyly	0.467	0.533
Q69 Polydactyly	0.467	0.533
Q68 Other congenital musculoskeletal deformities	0.467	0.533
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.467	0.533
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.467	0.533
T20 Burn and corrosion of head and neck	0.466	0.534
Y40 Systemic antibiotics	0.466	0.534
S63.5 Sprain and strain of wrist	0.464	0.535
T65 Toxic effect of other and unspecified substances	0.464	0.536
T62 Toxic effect of other noxious substances eaten as food	0.464	0.536
T61 Toxic effect of noxious substances eaten as seafood	0.464	0.536
T60 Toxic effect of pesticides	0.464	0.536
T57 Toxic effect of other inorganic substances	0.464	0.536
T56 Toxic effect of metals	0.464	0.536
T54 Toxic effect of corrosive substances	0.464	0.536
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.464	0.536
T52 Toxic effect of organic solvents	0.464	0.536
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.464	0.536
T55 Toxic effect of soaps and detergents	0.464	0.536
Q89 Other congenital malformations, not elsewhere classified	0.464	0.536
Q66.8 Other congenital deformities of feet	0.463	0.537
S40.0 Contusion of shoulder and upper arm	0.462	0.538
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.459	0.541
Q85 Phakomatoses, not elsewhere classified	0.459	0.541
H20.1 Chronic iridocyclitis	0.458	0.542
D37.0 Lip, oral cavity and pharynx	0.458	0.542
G24.9 Dystonia, unspecified	0.458	0.542
D45 Polycythaemia vera	0.457	0.543
G70 Myasthenia gravis and other myoneural disorders	0.457	0.543
W13 Fall from, out of or through building or structure	0.457	0.543
T88.4 Failed or difficult intubation	0.456	0.544
Y51 Drugs primarily affecting the autonomic nervous system	0.456	0.544
Q26 Congenital malformations of great veins	0.456	0.544
Q25 Congenital malformations of great arteries	0.456	0.544
Q22 Congenital malformations of pulmonary and tricuspid valves	0.456	0.544
Q20 Congenital malformations of cardiac chambers and connexions	0.456	0.544
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.455	0.545
H21 Other disorders of iris and ciliary body	0.455	0.545
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.455	0.545
S88 Traumatic amputation of lower leg	0.454	0.545
S87 Crushing injury of lower leg	0.454	0.545
S86 Injury of muscle and tendon at lower leg level	0.454	0.545
S85 Injury of blood vessels at lower leg level	0.454	0.545
S84 Injury of nerves at lower leg level	0.454	0.545
V29 Motorcycle rider injured in other and unspecified transport accidents	0.454	0.546
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.454	0.546
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.454	0.546
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.454	0.546
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.454	0.546
V21 Motorcycle rider injured in collision with pedal cycle	0.454	0.546
V20 Motorcycle rider injured in collision with pedestrian or animal	0.454	0.546
G23 Other degenerative diseases of basal ganglia	0.454	0.546
G21 Secondary Parkinsonism	0.454	0.546
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.454	0.546
G22 Parkinsonism in diseases classified elsewhere	0.454	0.546
W17.4 Street and highway	0.454	0.546
T13 Other injuries of lower limb, level unspecified	0.454	0.546
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.454	0.546
S36 Injury of intra-abdominal organs	0.454	0.546
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.454	0.546
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.454	0.546
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.454	0.546
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.454	0.546
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.454	0.546
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.454	0.546
S89 Other and unspecified injuries of lower leg	0.453	0.546
S32 Fracture of lumbar spine and pelvis	0.453	0.547
W78 Inhalation of gastric contents	0.453	0.547
G71 Primary disorders of muscles	0.453	0.547
F40-F48 Neurotic, stress-related and somatoform disorders	0.452	0.548
S63.0 Dislocation of wrist	0.452	0.548
S19.9 Unspecified injury of neck	0.451	0.549
Q66.7 Pes cavus	0.449	0.551
G82 Paraplegia and tetraplegia	0.449	0.551
C79 Secondary malignant neoplasm of other sites	0.449	0.551
Y84.9 Medical procedure, unspecified	0.448	0.551
Y84.7 Blood-sampling	0.448	0.551
Y84.5 Insertion of gastric or duodenal sound	0.448	0.551
Y84.3 Shock therapy	0.448	0.551
T86 Failure and rejection of transplanted organs and tissues	0.447	0.552
C56 Malignant neoplasm of ovary	0.448	0.552
T18.9 Foreign body in alimentary tract, part unspecified	0.447	0.553
T91.1 Sequelae of fracture of spine	0.447	0.553
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.446	0.554
S60.2 Contusion of other parts of wrist and hand	0.445	0.555
T66-T78 Other and unspecified effects of external causes	0.445	0.555
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.445	0.555
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.445	0.555
T80.6 Other serum reactions	0.445	0.555
T80.5 Anaphylactic shock due to serum	0.445	0.555
T80.4 Rh incompatibility reaction	0.445	0.555
T80.3 ABO incompatibility reaction	0.445	0.555
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.445	0.555
Y84.4 Aspiration of fluid	0.445	0.555
S51.9 Open wound of forearm, part unspecified	0.444	0.556
S90.9 Superficial injury of ankle and foot, unspecified	0.444	0.556
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.443	0.557
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.443	0.557
S80.1 Contusion of other and unspecified parts of lower leg	0.443	0.557
C73 Malignant neoplasm of thyroid gland	0.443	0.557
W11.6 Industrial and construction area	0.443	0.557
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.442	0.558
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.442	0.558
X40-X49 Accidental poisoning by and exposure to noxious substances	0.441	0.558
W06.0 Home	0.439	0.561
W03.8 Other specified place	0.439	0.561
W03.3 Sports and athletics area	0.439	0.561
W03.7 Farm	0.439	0.561
W03.6 Industrial and construction area	0.439	0.561
W03.5 Trade and service area	0.439	0.561
W03.4 Street and highway	0.439	0.561
W03.2 School, other institution and public administrative area	0.439	0.561
W03.1 Residential institution	0.439	0.561
W03.0 Home	0.439	0.561
T80.2 Infections following infusion, transfusion and therapeutic injection	0.438	0.561
T59.8 Other specified gases, fumes and vapours	0.438	0.562
Y42.5 Other oestrogens and progestogens	0.438	0.562
T87.5 Necrosis of amputation stump	0.436	0.563
T87.4 Infection of amputation stump	0.436	0.563
T87.3 Neuroma of amputation stump	0.436	0.563
T87.2 Complications of other reattached body part	0.436	0.563
T87.1 Complications of reattached (part of) lower extremity	0.436	0.563
T87.0 Complications of reattached (part of) upper extremity	0.436	0.563
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.437	0.563
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.436	0.563
Q84 Other congenital malformations of integument	0.436	0.563
Q83 Congenital malformations of breast	0.436	0.563
Q81 Epidermolysis bullosa	0.436	0.563
Q80 Congenital ichthyosis	0.436	0.563
F80-F89 Disorders of psychological development	0.436	0.564
H44 Disorders of globe	0.436	0.564
G24.5 Blepharospasm	0.436	0.564
G50-G59 Nerve, nerve root and plexus disorders	0.436	0.564
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.435	0.565
S91.1 Open wound of toe(s) without damage to nail	0.435	0.565
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.435	0.565
T11 Other injuries of upper limb, level unspecified	0.435	0.565
T09 Other injuries of spine and trunk, level unspecified	0.435	0.565
T12.X1 Fracture of lower limb, level unspecified (open)	0.435	0.565
T12.X0 Fracture of lower limb, level unspecified (closed)	0.435	0.565
T12 Fracture of lower limb, level unspecified	0.435	0.565
T10.X1 Fracture of upper limb, level unspecified (open)	0.435	0.565
T10.X0 Fracture of upper limb, level unspecified (closed)	0.435	0.565
T10 Fracture of upper limb, level unspecified	0.435	0.565
T08.X1 Fracture of spine, level unspecified (open)	0.435	0.565
T08.X0 Fracture of spine, level unspecified (closed)	0.435	0.565
T08 Fracture of spine, level unspecified	0.435	0.565
W01.6 Industrial and construction area	0.435	0.565
H52.0 Hypermetropia	0.435	0.565
D37.7 Other digestive organs	0.435	0.565
G24.3 Spasmodic torticollis	0.435	0.565
D37.4 Colon	0.434	0.565
S49 Other and unspecified injuries of shoulder and upper arm	0.434	0.566
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.434	0.566
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.434	0.566
S41 Open wound of shoulder and upper arm	0.433	0.567
S80.0 Contusion of knee	0.433	0.567
S79 Other and unspecified injuries of hip and thigh	0.433	0.567
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.433	0.567
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.432	0.568
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.431	0.569
W08 Fall involving other furniture	0.431	0.569
T14 Injury of unspecified body region	0.430	0.570
S30 Superficial injury of abdomen, lower back and pelvis	0.430	0.570
T82.4 Mechanical complication of vascular dialysis catheter	0.430	0.570
V96 Accident to nonpowered aircraft causing injury to occupant	0.429	0.571
V95 Accident to powered aircraft causing injury to occupant	0.429	0.571

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations