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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs916920
log Bayes Factor = 74.5648
Chromosome 6   position 30,877,202  (GRCh37) Explore rs916920 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.9 Without complications
0.000 0.003 0.997
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.017 0.983
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.018 0.982
E10.4 With neurological complications
0.000 0.041 0.959
M07.39 Other psoriatic arthropathies (Site unspecified)
0.939 0.061 0.000
M07.3 Other psoriatic arthropathies
0.939 0.061 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.934 0.066 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.067 0.933
E10.3 With ophthalmic complications
0.000 0.099 0.901
E16 Other disorders of pancreatic internal secretion
0.000 0.103 0.897
L40.8 Other psoriasis
0.890 0.110 0.000
E10.5 With peripheral circulatory complications
0.000 0.118 0.882
E07 Other disorders of thyroid
0.000 0.120 0.880
E16.2 Hypoglycaemia, unspecified
0.000 0.127 0.873
E10.1 With ketoacidosis
0.000 0.127 0.873
L40.1 Generalised pustular psoriasis
0.854 0.146 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.166 0.834
E10.6 With other specified complications
0.000 0.166 0.834
M07.34 Other psoriatic arthropathies (Hand)
0.824 0.176 0.000
E10.2 With renal complications
0.000 0.184 0.816
E10.0 With coma
0.000 0.188 0.812
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.197 0.803
M07.36 Other psoriatic arthropathies (Lower leg)
0.800 0.200 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.779 0.220 0.000
E06 Thyroiditis
0.000 0.241 0.758
E50-E64 Other nutritional deficiencies
0.000 0.242 0.758
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.243 0.757
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.266 0.734
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.295 0.704
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.303 0.696
M07.38 Other psoriatic arthropathies (Other)
0.673 0.327 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.673 0.327 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.673 0.327 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.673 0.327 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.673 0.327 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.331 0.669
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.357 0.643
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.357 0.643
E16.4 Abnormal secretion of gastrin
0.000 0.357 0.643
E16.3 Increased secretion of glucagon
0.000 0.357 0.643
E07.1 Dyshormogenetic goitre
0.000 0.369 0.631
E07.0 Hypersecretion of calcitonin
0.000 0.369 0.631
E55 Vitamin D deficiency
0.000 0.379 0.621
E03.8 Other specified hypothyroidism
0.000 0.394 0.606
E06.3 Autoimmune thyroiditis
0.000 0.416 0.584
E13 Other specified diabetes mellitus
0.000 0.438 0.562
E10.8 With unspecified complications
0.000 0.446 0.553
E16.1 Other hypoglycaemia
0.000 0.447 0.553
E06.9 Thyroiditis, unspecified
0.000 0.455 0.545
E06.5 Other chronic thyroiditis
0.000 0.456 0.544
E06.4 Drug-induced thyroiditis
0.000 0.456 0.544
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.456 0.544
E06.1 Subacute thyroiditis
0.000 0.456 0.544
E06.0 Acute thyroiditis
0.000 0.456 0.544
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.456 0.543
E63 Other nutritional deficiencies
0.000 0.456 0.543
E56 Other vitamin deficiencies
0.000 0.456 0.543
E51 Thiamine deficiency
0.000 0.456 0.543
E50 Vitamin A deficiency
0.000 0.456 0.543
E60 Dietary zinc deficiency
0.000 0.456 0.543
E59 Dietary selenium deficiency
0.000 0.456 0.543
E58 Dietary calcium deficiency
0.000 0.456 0.543
E54 Ascorbic acid deficiency
0.000 0.456 0.543
E52 Niacin deficiency [pellagra]
0.000 0.456 0.543
E61 Deficiency of other nutrient elements
0.000 0.471 0.529
E55.9 Vitamin D deficiency, unspecified
0.000 0.477 0.523
E53 Deficiency of other B group vitamins
0.000 0.478 0.522
K90 Intestinal malabsorption
0.000 0.478 0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E65-E68 Obesity and other hyperalimentation
0.000 0.492 0.508
E12.9 Without complications
0.000 0.495 0.505
E12.8 With unspecified complications
0.000 0.495 0.505
E12.7 With multiple complications
0.000 0.495 0.505
E12.6 With other specified complications
0.000 0.495 0.505
E12.5 With peripheral circulatory complications
0.000 0.495 0.505
E12.4 With neurological complications
0.000 0.495 0.505
E12.3 With ophthalmic complications
0.000 0.495 0.505
E12.2 With renal complications
0.000 0.495 0.505
E12.1 With ketoacidosis
0.000 0.495 0.505
E12.0 With coma
0.000 0.495 0.505
E40-E46 Malnutrition
0.001 0.510 0.489
E14 Unspecified diabetes mellitus
0.000 0.534 0.466
E04 Other non-toxic goitre
0.000 0.536 0.464
E55.0 Rickets, active
0.000 0.555 0.445
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.564 0.436
K90.9 Intestinal malabsorption, unspecified
0.000 0.583 0.417
E07.8 Other specified disorders of thyroid
0.001 0.586 0.413
E14.3 With ophthalmic complications
0.000 0.588 0.411
M07 Psoriatic and enteropathic arthropathies
0.410 0.590 0.000
E13.8 With unspecified complications
0.000 0.597 0.403
E13.7 With multiple complications
0.000 0.597 0.403
E13.6 With other specified complications
0.000 0.597 0.403
E13.5 With peripheral circulatory complications
0.000 0.597 0.403
E13.4 With neurological complications
0.000 0.597 0.403
E13.3 With ophthalmic complications
0.000 0.597 0.403
E13.2 With renal complications
0.000 0.597 0.403
E13.1 With ketoacidosis
0.000 0.597 0.403
E13.0 With coma
0.000 0.597 0.403
E53.9 Vitamin B deficiency, unspecified
0.000 0.601 0.398
E50.9 Vitamin A deficiency, unspecified
0.000 0.610 0.390
E50.8 Other manifestations of vitamin A deficiency
0.000 0.610 0.390
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.610 0.390
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.610 0.390
E50.5 Vitamin A deficiency with night blindness
0.000 0.610 0.390
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.610 0.390
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.610 0.390
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.610 0.390
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.610 0.390
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.610 0.390
E51.9 Thiamine deficiency, unspecified
0.000 0.610 0.390
E51.8 Other manifestations of thiamine deficiency
0.000 0.610 0.390
E51.2 Wernicke's encephalopathy
0.000 0.610 0.390
E51.1 Beriberi
0.000 0.610 0.390
E56.9 Vitamin deficiency, unspecified
0.000 0.610 0.390
E56.8 Deficiency of other vitamins
0.000 0.610 0.390
E56.1 Deficiency of vitamin K
0.000 0.610 0.390
E56.0 Deficiency of vitamin E
0.000 0.610 0.390
E63.9 Nutritional deficiency, unspecified
0.000 0.610 0.390
E63.8 Other specified nutritional deficiencies
0.000 0.610 0.390
E63.1 Imbalance of constituents of food intake
0.000 0.610 0.390
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.610 0.390
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.610 0.390
E64.8 Sequelae of other nutritional deficiencies
0.000 0.610 0.390
E64.3 Sequelae of rickets
0.000 0.610 0.390
E64.2 Sequelae of vitamin C deficiency
0.000 0.610 0.390
E64.1 Sequelae of vitamin A deficiency
0.000 0.610 0.390
E64.0 Sequelae of protein-energy malnutrition
0.000 0.610 0.390
E61.2 Magnesium deficiency
0.000 0.613 0.387
E61.9 Deficiency of nutrient element, unspecified
0.000 0.621 0.379
E61.8 Deficiency of other specified nutrient elements
0.000 0.621 0.379
E61.7 Deficiency of multiple nutrient elements
0.000 0.621 0.379
E61.6 Vanadium deficiency
0.000 0.621 0.379
E61.5 Molybdenum deficiency
0.000 0.621 0.379
E61.4 Chromium deficiency
0.000 0.621 0.379
E61.3 Manganese deficiency
0.000 0.621 0.379
E61.0 Copper deficiency
0.000 0.621 0.379
E53.1 Pyridoxine deficiency
0.000 0.625 0.375
E53.0 Riboflavin deficiency
0.000 0.625 0.375
K90.3 Pancreatic steatorrhoea
0.000 0.626 0.374
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.626 0.374
K90.1 Tropical sprue
0.000 0.626 0.374
E04.9 Non-toxic goitre, unspecified
0.000 0.629 0.371
E67 Other hyperalimentation
0.000 0.635 0.364
E68 Sequelae of hyperalimentation
0.000 0.635 0.364
E61.1 Iron deficiency
0.000 0.644 0.356
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.648 0.351
E45 Retarded development following protein-energy malnutrition
0.001 0.648 0.351
E43 Unspecified severe protein-energy malnutrition
0.001 0.648 0.351
E42 Marasmic kwashiorkor
0.001 0.648 0.351
E41 Nutritional marasmus
0.001 0.648 0.351
E40 Kwashiorkor
0.001 0.648 0.351
E14.7 With multiple complications
0.000 0.666 0.334
E14.6 With other specified complications
0.000 0.666 0.334
E14.2 Withrenal complications
0.000 0.666 0.334
E14.0 With coma
0.000 0.666 0.334
E04.8 Other specified non-toxic goitre
0.000 0.667 0.333
E14.1 With ketoacidosis
0.000 0.671 0.328
E53.8 Deficiency of other specified B group vitamins
0.000 0.679 0.321
E14.8 With unspecified complications
0.000 0.680 0.320
E14.5 With peripheral circulatory complications
0.000 0.699 0.301
M07.6 Other enteropathic arthropathies
0.294 0.706 0.000
M07.5 Arthropathy in ulcerative colitis
0.294 0.706 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.294 0.706 0.000
M07.2 Psoriatic spondylitis
0.294 0.706 0.000
M07.1 Arthritis mutilans
0.294 0.706 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.294 0.706 0.000
E65 Localised adiposity
0.000 0.713 0.287
E66 Obesity
0.000 0.713 0.287
E04.0 Non-toxic diffuse goitre
0.000 0.729 0.271
E04.2 Non-toxic multinodular goitre
0.000 0.730 0.270
E66.8 Other obesity
0.000 0.734 0.266
E67.8 Other specified hyperalimentation
0.000 0.738 0.261
E67.3 Hypervitaminosis D
0.000 0.738 0.261
E67.2 Megavitamin-B6 syndrome
0.000 0.738 0.261
E67.1 Hypercarotenaemia
0.000 0.738 0.261
E67.0 Hypervitaminosis A
0.000 0.738 0.261
E13.9 Without complications
0.000 0.739 0.260
E20-E35 Disorders of other endocrine glands
0.000 0.744 0.256
E14.4 With neurological complications
0.000 0.744 0.256
K90.8 Other intestinal malabsorption
0.001 0.744 0.255
E44.1 Mild protein-energy malnutrition
0.001 0.748 0.252
E44.0 Moderate protein-energy malnutrition
0.001 0.748 0.252
E27 Other disorders of adrenal gland
0.000 0.768 0.232
E27.1 Primary adrenocortical insufficiency
0.000 0.771 0.229
L40-L45 Papulosquamous disorders
0.224 0.776 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.785 0.215
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.211 0.789 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.211 0.789 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.211 0.789 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.211 0.789 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.211 0.789 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.211 0.789 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.211 0.789 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.211 0.789 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.211 0.789 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.211 0.789 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.211 0.789 0.000
M07.18 Arthritis mutilans (Other)
0.211 0.789 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.211 0.789 0.000
M07.16 Arthritis mutilans (Lower leg)
0.211 0.789 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.211 0.789 0.000
M07.14 Arthritis mutilans (Hand)
0.211 0.789 0.000
M07.13 Arthritis mutilans (Forearm)
0.211 0.789 0.000
M07.12 Arthritis mutilans (Upper arm)
0.211 0.789 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.211 0.789 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.211 0.789 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.211 0.789 0.000
M07.28 Psoriatic spondylitis (Other)
0.211 0.789 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.211 0.789 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.211 0.789 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.211 0.789 0.000
M07.24 Psoriatic spondylitis (Hand)
0.211 0.789 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.211 0.789 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.211 0.789 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.211 0.789 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.211 0.789 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.211 0.789 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.211 0.789 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.211 0.789 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.211 0.789 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.211 0.789 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.211 0.789 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.211 0.789 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.211 0.789 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.211 0.789 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.211 0.789 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.211 0.789 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.211 0.789 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.211 0.789 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.211 0.789 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.211 0.789 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.211 0.789 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.211 0.789 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.211 0.789 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.211 0.789 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.211 0.789 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.211 0.789 0.000
M07.68 Other enteropathic arthropathies (Other)
0.211 0.789 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.211 0.789 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.211 0.789 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.211 0.789 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.211 0.789 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.211 0.789 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.211 0.789 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.211 0.789 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.211 0.789 0.000
E66.1 Drug-induced obesity
0.000 0.794 0.206
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.816 0.184
E32 Diseases of thymus
0.000 0.816 0.184
E31 Polyglandular dysfunction
0.000 0.816 0.184
E30 Disorders of puberty, not elsewhere classified
0.000 0.816 0.184
E25 Adrenogenital disorders
0.000 0.816 0.184
E34 Other endocrine disorders
0.000 0.824 0.176
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.824 0.176
E29 Testicular dysfunction
0.000 0.826 0.174
E20 Hypoparathyroidism
0.000 0.828 0.172
E27.8 Other specified disorders of adrenal gland
0.000 0.828 0.172
E27.5 Adrenomedullary hyperfunction
0.000 0.834 0.166
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.834 0.166
E27.0 Other adrenocortical overactivity
0.000 0.834 0.166
E22 Hyperfunction of pituitary gland
0.000 0.838 0.162
L44 Other papulosquamous disorders
0.161 0.839 0.000
L41 Parapsoriasis
0.161 0.839 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.161 0.839 0.000
E26 Hyperaldosteronism
0.000 0.841 0.159
E24 Cushing's syndrome
0.000 0.842 0.158
E27.2 Addisonian crisis
0.000 0.844 0.156
L42 Pityriasis rosea
0.155 0.844 0.000
E28 Ovarian dysfunction
0.000 0.847 0.153
E66.0 Obesity due to excess calories
0.000 0.850 0.150
E46 Unspecified protein-energy malnutrition
0.002 0.862 0.136
E34.9 Endocrine disorder, unspecified
0.000 0.866 0.134
E34.0 Carcinoid syndrome
0.000 0.868 0.132
E25.9 Adrenogenital disorder, unspecified
0.000 0.868 0.132
E25.8 Other adrenogenital disorders
0.000 0.868 0.132
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.868 0.132
E30.9 Disorder of puberty, unspecified
0.000 0.868 0.132
E30.8 Other disorders of puberty
0.000 0.868 0.132
E30.1 Precocious puberty
0.000 0.868 0.132
E30.0 Delayed puberty
0.000 0.868 0.132
E31.9 Polyglandular dysfunction, unspecified
0.000 0.868 0.132
E31.8 Other polyglandular dysfunction
0.000 0.868 0.132
E31.1 Polyglandular hyperfunction
0.000 0.868 0.132
E31.0 Autoimmune polyglandular failure
0.000 0.868 0.132
E32.9 Disease of thymus, unspecified
0.000 0.868 0.132
E32.8 Other diseases of thymus
0.000 0.868 0.132
E32.1 Abscess of thymus
0.000 0.868 0.132
E32.0 Persistent hyperplasia of thymus
0.000 0.868 0.132
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.868 0.132
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.868 0.132
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.868 0.132
E22.1 Hyperprolactinaemia
0.000 0.871 0.128
E34.5 Androgen resistance syndrome
0.000 0.874 0.126
E34.4 Constitutional tall stature
0.000 0.874 0.126
E34.3 Short stature, not elsewhere classified
0.000 0.874 0.126
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.874 0.126
E34.1 Other hypersecretion of intestinal hormones
0.000 0.874 0.126
E29.9 Testicular dysfunction, unspecified
0.000 0.875 0.125
E29.8 Other testicular dysfunction
0.000 0.875 0.125
E29.0 Testicular hyperfunction
0.000 0.875 0.125
E20.8 Other hypoparathyroidism
0.000 0.876 0.124
E20.1 Pseudohypoparathyroidism
0.000 0.876 0.124
E20.0 Idiopathic hypoparathyroidism
0.000 0.876 0.124
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.878 0.122
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.883 0.116
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.884 0.116
E22.8 Other hyperfunction of pituitary gland
0.000 0.884 0.116
L41.9 Parapsoriasis, unspecified
0.115 0.884 0.000
L41.8 Other parapsoriasis
0.115 0.884 0.000
L41.5 Retiform parapsoriasis
0.115 0.884 0.000
L41.4 Large plaque parapsoriasis
0.115 0.884 0.000
L41.3 Small plaque parapsoriasis
0.115 0.884 0.000
L41.2 Lymphomatoid papulosis
0.115 0.884 0.000
L41.1 Pityriasis lichenoides chronica
0.115 0.884 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.115 0.884 0.000
L44.9 Papulosquamous disorder, unspecified
0.115 0.884 0.000
L44.8 Other specified papulosquamous disorders
0.115 0.884 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.115 0.884 0.000
L44.3 Lichen ruber moniliformis
0.115 0.884 0.000
L44.2 Lichen striatus
0.115 0.884 0.000
L44.1 Lichen nitidus
0.115 0.884 0.000
L44.0 Pityriasis rubra pilaris
0.115 0.884 0.000
E29.1 Testicular hypofunction
0.000 0.885 0.115
E24.2 Drug-induced Cushing's syndrome
0.000 0.885 0.115
E26.9 Hyperaldosteronism, unspecified
0.000 0.886 0.114
E26.8 Other hyperaldosteronism
0.000 0.886 0.114
E26.1 Secondary hyperaldosteronism
0.000 0.886 0.114
E24.8 Other Cushing's syndrome
0.000 0.886 0.114
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.886 0.114
E24.3 Ectopic ACTH syndrome
0.000 0.886 0.114
E24.1 Nelson's syndrome
0.000 0.886 0.114
E20.9 Hypoparathyroidism, unspecified
0.000 0.888 0.112
E28.9 Ovarian dysfunction, unspecified
0.000 0.890 0.110
E28.8 Other ovarian dysfunction
0.000 0.890 0.110
E28.1 Androgen excess
0.000 0.890 0.110
E28.0 Oestrogen excess
0.000 0.890 0.110
E22.0 Acromegaly and pituitary gigantism
0.000 0.891 0.109
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.893 0.107
E23 Hypofunction and other disorders of pituitary gland
0.000 0.893 0.107
E28.3 Primary ovarian failure
0.000 0.893 0.107
E27.9 Disorder of adrenal gland, unspecified
0.000 0.896 0.103
E24.0 Pituitary-dependent Cushing's disease
0.000 0.897 0.102
E24.9 Cushing's syndrome, unspecified
0.000 0.899 0.100
E34.8 Other specified endocrine disorders
0.000 0.902 0.098
E26.0 Primary hyperaldosteronism
0.000 0.910 0.089
E28.2 Polycystic ovarian syndrome
0.000 0.916 0.084
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.919 0.081
L43 Lichen planus
0.079 0.920 0.001
E21.4 Other specified disorders of parathyroid gland
0.000 0.923 0.077
E21.2 Other hyperparathyroidism
0.000 0.923 0.077
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.923 0.077
E23.1 Drug-induced hypopituitarism
0.000 0.923 0.077
E14.9 Without complications
0.000 0.925 0.075
F33 Recurrent depressive disorder
0.075 0.925 0.000
E21.0 Primary hyperparathyroidism
0.000 0.926 0.074
E23.0 Hypopituitarism
0.000 0.927 0.073
F30-F39 Mood [affective] disorders
0.072 0.928 0.000
Chapter V Mental and behavioural disorders
0.072 0.928 0.000
F33.9 Recurrent depressive disorder, unspecified
0.072 0.928 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.929 0.071
E23.2 Diabetes insipidus
0.000 0.930 0.070
F60-F69 Disorders of adult personality and behaviour
0.067 0.933 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.067 0.933 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.066 0.934 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.066 0.934 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.066 0.934 0.000
F60 Specific personality disorders
0.065 0.935 0.000
R41.0 Disorientation, unspecified
0.000 0.935 0.065
K90-K93 Other diseases of the digestive system
0.000 0.936 0.064
E23.6 Other disorders of pituitary gland
0.000 0.937 0.063
F40 Phobic anxiety disorders
0.062 0.938 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.062 0.938 0.000
F60.3 Emotionally unstable personality disorder
0.061 0.939 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.940 0.059
F34 Persistent mood [affective] disorders
0.060 0.940 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.059 0.941 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.059 0.941 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.059 0.941 0.000
F52.2 Failure of genital response
0.059 0.941 0.000
F48 Other neurotic disorders
0.058 0.942 0.000
L43.3 Subacute (active) lichen planus
0.057 0.943 0.001
L43.2 Lichenoid drug reaction
0.057 0.943 0.001
L43.1 Bullous lichen planus
0.057 0.943 0.001
L43.0 Hypertrophic lichen planus
0.057 0.943 0.001
F40.2 Specific (isolated) phobias
0.057 0.943 0.000
F25 Schizoaffective disorders
0.057 0.943 0.000
F20 Schizophrenia
0.057 0.943 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.944 0.056
F32 Depressive episode
0.056 0.944 0.000
E23.7 Disorder of pituitary gland, unspecified
0.001 0.945 0.055
F60.7 Dependent personality disorder
0.055 0.945 0.000
F44 Dissociative [conversion] disorders
0.055 0.945 0.000
F22 Persistent delusional disorders
0.054 0.946 0.000
F30 Manic episode
0.054 0.946 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.054 0.946 0.000
F70-F79 Mental retardation
0.054 0.946 0.000
F33.8 Other recurrent depressive disorders
0.054 0.946 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.054 0.946 0.000
F23 Acute and transient psychotic disorders
0.053 0.947 0.000
F60.5 Anankastic personality disorder
0.053 0.947 0.000
F20.9 Schizophrenia, unspecified
0.052 0.948 0.000
F50 Eating disorders
0.052 0.948 0.000
F38 Other mood [affective] disorders
0.052 0.948 0.000
F11 Mental and behavioural disorders due to use of opioids
0.052 0.948 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.052 0.948 0.000
F48.0 Neurasthenia
0.051 0.949 0.000
F34.1 Dysthymia
0.050 0.949 0.000
F32.0 Mild depressive episode
0.050 0.950 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.049 0.951 0.000
F42 Obsessive-compulsive disorder
0.049 0.951 0.000
F40.9 Phobic anxiety disorder, unspecified
0.049 0.951 0.000
F25.9 Schizoaffective disorder, unspecified
0.049 0.951 0.000
F68 Other disorders of adult personality and behaviour
0.048 0.952 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.048 0.952 0.000
F65 Disorders of sexual preference
0.048 0.952 0.000
F63 Habit and impulse disorders
0.048 0.952 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.048 0.952 0.000
F61 Mixed and other personality disorders
0.048 0.952 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.048 0.952 0.000
F51 Nonorganic sleep disorders
0.048 0.952 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.048 0.952 0.000
F55 Abuse of non-dependence-producing substances
0.048 0.952 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.048 0.952 0.000
F40.0 Agoraphobia
0.048 0.952 0.000
F28 Other nonorganic psychotic disorders
0.047 0.953 0.000
F24 Induced delusional disorder
0.047 0.953 0.000
F21 Schizotypal disorder
0.047 0.953 0.000
F69 Unspecified disorder of adult personality and behaviour
0.047 0.953 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.047 0.953 0.000
F60.8 Other specific personality disorders
0.047 0.953 0.000
F60.4 Histrionic personality disorder
0.047 0.953 0.000
F60.2 Dissocial personality disorder
0.047 0.953 0.000
F60.1 Schizoid personality disorder
0.047 0.953 0.000
F60.0 Paranoid personality disorder
0.047 0.953 0.000
F60.6 Anxious [avoidant] personality disorder
0.047 0.953 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.954 0.046
F39 Unspecified mood [affective] disorder
0.046 0.954 0.000
F25.0 Schizoaffective disorder, manic type
0.046 0.954 0.000
L43.8 Other lichen planus
0.045 0.954 0.001
F22.0 Delusional disorder
0.046 0.954 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.046 0.954 0.000
F60.9 Personality disorder, unspecified
0.046 0.954 0.000
F40.8 Other phobic anxiety disorders
0.046 0.954 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.045 0.955 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.045 0.955 0.000
F40.1 Social phobias
0.044 0.955 0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.044 0.955 0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.044 0.955 0.000
F52.7 Excessive sexual drive
0.044 0.955 0.000
F52.6 Nonorganic dyspareunia
0.044 0.955 0.000
F52.5 Nonorganic vaginismus
0.044 0.955 0.000
F52.4 Premature ejaculation
0.044 0.955 0.000
F52.3 Orgasmic dysfunction
0.044 0.955 0.000
F52.1 Sexual aversion and lack of sexual enjoyment
0.044 0.955 0.000
F52.0 Lack or loss of sexual desire
0.044 0.955 0.000
F48.9 Neurotic disorder, unspecified
0.044 0.956 0.000
F30.1 Mania without psychotic symptoms
0.044 0.956 0.000
F45 Somatoform disorders
0.044 0.956 0.000
F12.1 Harmful use
0.044 0.956 0.000
F32.9 Depressive episode, unspecified
0.044 0.956 0.000
F30.2 Mania with psychotic symptoms
0.043 0.956 0.000
F44.0 Dissociative amnesia
0.043 0.957 0.000
F11.2 Dependence syndrome
0.043 0.957 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.043 0.957 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.043 0.957 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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