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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9257691
log Bayes Factor = 53.678
Chromosome 6   position 29,268,929  (GRCh37) Explore rs9257691 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E00-E07 Disorders of thyroid gland
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.035 0.965
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.043 0.957
E10.1 With ketoacidosis
0.000 0.098 0.902
E10.4 With neurological complications
0.000 0.107 0.893
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.155 0.845
E16.1 Other hypoglycaemia
0.000 0.191 0.809
E05.8 Other thyrotoxicosis
0.000 0.210 0.790
E13 Other specified diabetes mellitus
0.000 0.214 0.786
E14 Unspecified diabetes mellitus
0.000 0.223 0.777
E10.7 With multiple complications
0.000 0.240 0.760
E40-E46 Malnutrition
0.000 0.269 0.731
E10.0 With coma
0.000 0.272 0.728
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
E14.3 With ophthalmic complications
0.000 0.302 0.698
E07 Other disorders of thyroid
0.000 0.341 0.659
E13.9 Without complications
0.000 0.346 0.654
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.354 0.646
E10.6 With other specified complications
0.000 0.357 0.643
E10.5 With peripheral circulatory complications
0.000 0.370 0.630
E14.6 With other specified complications
0.000 0.396 0.604
E14.1 With ketoacidosis
0.000 0.398 0.602
E14.8 With unspecified complications
0.000 0.399 0.601
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.403 0.597
K90 Intestinal malabsorption
0.000 0.405 0.595
E14.4 With neurological complications
0.000 0.423 0.577
E13.8 With unspecified complications
0.000 0.436 0.564
E13.7 With multiple complications
0.000 0.436 0.564
E13.6 With other specified complications
0.000 0.436 0.564
E13.5 With peripheral circulatory complications
0.000 0.436 0.564
E13.4 With neurological complications
0.000 0.436 0.564
E13.2 With renal complications
0.000 0.436 0.564
E13.1 With ketoacidosis
0.000 0.436 0.564
E13.0 With coma
0.000 0.436 0.564
E14.7 With multiple complications
0.000 0.443 0.557
E14.5 With peripheral circulatory complications
0.000 0.459 0.541
E46 Unspecified protein-energy malnutrition
0.000 0.459 0.541
E07.8 Other specified disorders of thyroid
0.000 0.464 0.535
E13.3 With ophthalmic complications
0.000 0.469 0.531
E14.0 With coma
0.000 0.472 0.527
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.475 0.525
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.475 0.524
E45 Retarded development following protein-energy malnutrition
0.000 0.475 0.524
E43 Unspecified severe protein-energy malnutrition
0.000 0.475 0.524
E42 Marasmic kwashiorkor
0.000 0.475 0.524
E41 Nutritional marasmus
0.000 0.475 0.524
E40 Kwashiorkor
0.000 0.475 0.524
E14.2 Withrenal complications
0.000 0.479 0.521
E06 Thyroiditis
0.000 0.483 0.517
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.511
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.520 0.480
E07.1 Dyshormogenetic goitre
0.000 0.527 0.473
E07.0 Hypersecretion of calcitonin
0.000 0.527 0.473
K90.9 Intestinal malabsorption, unspecified
0.000 0.531 0.469
E10.8 With unspecified complications
0.001 0.539 0.461
K90.3 Pancreatic steatorrhoea
0.000 0.573 0.427
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.573 0.427
K90.1 Tropical sprue
0.000 0.573 0.427
K90.8 Other intestinal malabsorption
0.000 0.576 0.424
E03 Other hypothyroidism
0.000 0.591 0.409
E06.1 Subacute thyroiditis
0.000 0.606 0.394
E06.9 Thyroiditis, unspecified
0.000 0.621 0.379
E44.1 Mild protein-energy malnutrition
0.000 0.624 0.376
E44.0 Moderate protein-energy malnutrition
0.000 0.624 0.376
E06.4 Drug-induced thyroiditis
0.000 0.629 0.371
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.629 0.371
E06.0 Acute thyroiditis
0.000 0.629 0.371
E65-E68 Obesity and other hyperalimentation
0.000 0.632 0.368
E06.5 Other chronic thyroiditis
0.000 0.637 0.363
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.689 0.311
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.691 0.309
E07.9 Disorder of thyroid, unspecified
0.000 0.704 0.296
E03.5 Myxoedema coma
0.000 0.706 0.294
E03.4 Atrophy of thyroid (acquired)
0.000 0.706 0.294
E03.3 Postinfectious hypothyroidism
0.000 0.706 0.294
E03.1 Congenital hypothyroidism without goitre
0.000 0.712 0.288
E67 Other hyperalimentation
0.000 0.736 0.264
E68 Sequelae of hyperalimentation
0.000 0.736 0.264
E03.8 Other specified hypothyroidism
0.000 0.767 0.233
E65 Localised adiposity
0.000 0.771 0.229
E50-E64 Other nutritional deficiencies
0.000 0.774 0.226
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.223 0.777 0.000
E67.8 Other specified hyperalimentation
0.000 0.810 0.189
E67.3 Hypervitaminosis D
0.000 0.810 0.189
E67.2 Megavitamin-B6 syndrome
0.000 0.810 0.189
E67.1 Hypercarotenaemia
0.000 0.810 0.189
E67.0 Hypervitaminosis A
0.000 0.810 0.189
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.838 0.162
E50 Vitamin A deficiency
0.000 0.838 0.162
E60 Dietary zinc deficiency
0.000 0.838 0.162
E59 Dietary selenium deficiency
0.000 0.838 0.162
E52 Niacin deficiency [pellagra]
0.000 0.838 0.162
E54 Ascorbic acid deficiency
0.000 0.840 0.160
E51 Thiamine deficiency
0.000 0.841 0.159
E20-E35 Disorders of other endocrine glands
0.000 0.842 0.158
E56 Other vitamin deficiencies
0.000 0.845 0.155
E58 Dietary calcium deficiency
0.000 0.849 0.151
E63 Other nutritional deficiencies
0.000 0.852 0.148
E24 Cushing's syndrome
0.000 0.854 0.146
E83 Disorders of mineral metabolism
0.137 0.862 0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.862 0.138
E21.3 Hyperparathyroidism, unspecified
0.000 0.867 0.133
E24.0 Pituitary-dependent Cushing's disease
0.000 0.874 0.126
E53 Deficiency of other B group vitamins
0.000 0.877 0.122
E24.9 Cushing's syndrome, unspecified
0.000 0.879 0.121
E50.9 Vitamin A deficiency, unspecified
0.000 0.883 0.116
E50.8 Other manifestations of vitamin A deficiency
0.000 0.883 0.116
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.883 0.116
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.883 0.116
E50.5 Vitamin A deficiency with night blindness
0.000 0.883 0.116
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.883 0.116
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.883 0.116
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.883 0.116
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.883 0.116
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.883 0.116
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.883 0.116
E64.8 Sequelae of other nutritional deficiencies
0.000 0.883 0.116
E64.3 Sequelae of rickets
0.000 0.883 0.116
E64.2 Sequelae of vitamin C deficiency
0.000 0.883 0.116
E64.1 Sequelae of vitamin A deficiency
0.000 0.883 0.116
E64.0 Sequelae of protein-energy malnutrition
0.000 0.883 0.116
E83.3 Disorders of phosphorus metabolism
0.115 0.885 0.000
E25 Adrenogenital disorders
0.000 0.885 0.115
E55 Vitamin D deficiency
0.000 0.885 0.115
E51.9 Thiamine deficiency, unspecified
0.000 0.886 0.114
E51.8 Other manifestations of thiamine deficiency
0.000 0.886 0.114
E51.1 Beriberi
0.000 0.886 0.114
E20 Hypoparathyroidism
0.000 0.886 0.114
E61 Deficiency of other nutrient elements
0.000 0.886 0.114
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.886 0.113
E32 Diseases of thymus
0.000 0.886 0.113
E30 Disorders of puberty, not elsewhere classified
0.000 0.886 0.113
E24.2 Drug-induced Cushing's syndrome
0.000 0.887 0.113
E56.9 Vitamin deficiency, unspecified
0.000 0.888 0.111
E56.8 Deficiency of other vitamins
0.000 0.888 0.111
E56.0 Deficiency of vitamin E
0.000 0.888 0.111
E51.2 Wernicke's encephalopathy
0.000 0.889 0.111
E06.3 Autoimmune thyroiditis
0.001 0.889 0.110
E31 Polyglandular dysfunction
0.000 0.891 0.109
E21.4 Other specified disorders of parathyroid gland
0.000 0.891 0.109
E63.8 Other specified nutritional deficiencies
0.000 0.894 0.106
E63.1 Imbalance of constituents of food intake
0.000 0.894 0.106
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.894 0.106
E24.8 Other Cushing's syndrome
0.000 0.895 0.104
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.895 0.104
E24.3 Ectopic ACTH syndrome
0.000 0.895 0.104
E24.1 Nelson's syndrome
0.000 0.895 0.104
E56.1 Deficiency of vitamin K
0.000 0.895 0.104
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.897 0.103
E83.8 Other disorders of mineral metabolism
0.098 0.901 0.001
E83.2 Disorders of zinc metabolism
0.098 0.901 0.001
E83.0 Disorders of copper metabolism
0.098 0.901 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.097 0.902 0.001
E21.2 Other hyperparathyroidism
0.000 0.903 0.097
E11 Non-insulin-dependent diabetes mellitus
0.000 0.904 0.096
E28 Ovarian dysfunction
0.000 0.904 0.096
E14.9 Without complications
0.000 0.906 0.094
E53.9 Vitamin B deficiency, unspecified
0.000 0.906 0.094
E34 Other endocrine disorders
0.000 0.907 0.093
E63.9 Nutritional deficiency, unspecified
0.000 0.908 0.091
E29 Testicular dysfunction
0.000 0.911 0.088
E53.1 Pyridoxine deficiency
0.000 0.912 0.088
E53.0 Riboflavin deficiency
0.000 0.912 0.088
E11.6 With other specified complications
0.000 0.915 0.085
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.916 0.083
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.916 0.083
E20.9 Hypoparathyroidism, unspecified
0.000 0.917 0.083
E25.9 Adrenogenital disorder, unspecified
0.000 0.918 0.082
E25.8 Other adrenogenital disorders
0.000 0.918 0.082
E55.0 Rickets, active
0.000 0.918 0.082
E20.8 Other hypoparathyroidism
0.000 0.918 0.082
E20.1 Pseudohypoparathyroidism
0.000 0.918 0.082
E20.0 Idiopathic hypoparathyroidism
0.000 0.918 0.082
E61.9 Deficiency of nutrient element, unspecified
0.000 0.918 0.082
E61.8 Deficiency of other specified nutrient elements
0.000 0.918 0.082
E61.7 Deficiency of multiple nutrient elements
0.000 0.918 0.082
E61.6 Vanadium deficiency
0.000 0.918 0.082
E61.5 Molybdenum deficiency
0.000 0.918 0.082
E61.4 Chromium deficiency
0.000 0.918 0.082
E61.3 Manganese deficiency
0.000 0.918 0.082
E61.0 Copper deficiency
0.000 0.918 0.082
E30.9 Disorder of puberty, unspecified
0.000 0.918 0.081
E30.8 Other disorders of puberty
0.000 0.918 0.081
E30.1 Precocious puberty
0.000 0.918 0.081
E30.0 Delayed puberty
0.000 0.918 0.081
E32.9 Disease of thymus, unspecified
0.000 0.918 0.081
E32.8 Other diseases of thymus
0.000 0.918 0.081
E32.1 Abscess of thymus
0.000 0.918 0.081
E32.0 Persistent hyperplasia of thymus
0.000 0.918 0.081
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.918 0.081
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.918 0.081
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.918 0.081
E31.9 Polyglandular dysfunction, unspecified
0.000 0.921 0.078
E31.8 Other polyglandular dysfunction
0.000 0.921 0.078
E31.1 Polyglandular hyperfunction
0.000 0.921 0.078
E26 Hyperaldosteronism
0.000 0.924 0.076
E31.0 Autoimmune polyglandular failure
0.000 0.926 0.074
E11.0 With coma
0.000 0.929 0.071
E11.7 With multiple complications
0.000 0.931 0.069
E28.9 Ovarian dysfunction, unspecified
0.000 0.931 0.069
E28.8 Other ovarian dysfunction
0.000 0.931 0.069
E28.1 Androgen excess
0.000 0.931 0.069
E28.0 Oestrogen excess
0.000 0.931 0.069
E34.3 Short stature, not elsewhere classified
0.000 0.931 0.069
E22 Hyperfunction of pituitary gland
0.000 0.932 0.068
E61.2 Magnesium deficiency
0.000 0.932 0.068
E11.1 With ketoacidosis
0.000 0.932 0.068
E34.5 Androgen resistance syndrome
0.000 0.933 0.067
E34.4 Constitutional tall stature
0.000 0.933 0.067
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.933 0.067
E34.1 Other hypersecretion of intestinal hormones
0.000 0.933 0.067
E04 Other non-toxic goitre
0.001 0.933 0.066
E34.9 Endocrine disorder, unspecified
0.000 0.935 0.065
E28.3 Primary ovarian failure
0.000 0.936 0.064
E29.9 Testicular dysfunction, unspecified
0.000 0.936 0.064
E29.8 Other testicular dysfunction
0.000 0.936 0.064
E29.0 Testicular hyperfunction
0.000 0.936 0.064
E11.2 With renal complications
0.000 0.938 0.062
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.940 0.060
E34.0 Carcinoid syndrome
0.000 0.940 0.059
E34.8 Other specified endocrine disorders
0.000 0.942 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.942 0.058
E61.1 Iron deficiency
0.000 0.943 0.057
E26.8 Other hyperaldosteronism
0.000 0.945 0.055
E26.1 Secondary hyperaldosteronism
0.000 0.945 0.055
E03.9 Hypothyroidism, unspecified
0.000 0.946 0.054
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.947 0.053
S02.4 Fracture of malar and maxillary bones
0.000 0.949 0.051
E11.8 With unspecified complications
0.000 0.949 0.051
R31 Unspecified haematuria
0.051 0.949 0.000
E11.3 With ophthalmic complications
0.000 0.950 0.050
E22.8 Other hyperfunction of pituitary gland
0.000 0.951 0.049
E26.9 Hyperaldosteronism, unspecified
0.000 0.951 0.049
E22.1 Hyperprolactinaemia
0.000 0.952 0.048
E04.8 Other specified non-toxic goitre
0.001 0.952 0.047
Z71.8 Other specified counselling
0.047 0.953 0.000
K14.8 Other diseases of tongue
0.000 0.953 0.047
S02 Fracture of skull and facial bones
0.000 0.954 0.046
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.955 0.044
E83.4 Disorders of magnesium metabolism
0.041 0.959 0.001
E11.5 With peripheral circulatory complications
0.000 0.959 0.041
E21.0 Primary hyperparathyroidism
0.000 0.960 0.040
S02.8 Fractures of other skull and facial bones
0.000 0.960 0.040
S02.0 Fracture of vault of skull
0.000 0.960 0.040
E23 Hypofunction and other disorders of pituitary gland
0.000 0.960 0.040
K90-K93 Other diseases of the digestive system
0.000 0.961 0.039
E29.1 Testicular hypofunction
0.000 0.961 0.039
E22.0 Acromegaly and pituitary gigantism
0.000 0.962 0.037
S02.7 Multiple fractures involving skull and facial bones
0.000 0.962 0.038
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.963 0.037
S02.3 Fracture of orbital floor
0.000 0.963 0.037
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.964 0.036
S02.6 Fracture of mandible
0.000 0.964 0.036
S02.00 Fracture of vault of skull (closed)
0.000 0.964 0.036
S02.5 Fracture of tooth
0.000 0.964 0.036
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.965 0.035
E55.9 Vitamin D deficiency, unspecified
0.000 0.965 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
E04.9 Non-toxic goitre, unspecified
0.000 0.967 0.033
E04.0 Non-toxic diffuse goitre
0.001 0.968 0.031
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.968 0.031
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.969 0.031
S02.30 Fracture of orbital floor (closed)
0.000 0.970 0.030
E23.7 Disorder of pituitary gland, unspecified
0.000 0.970 0.030
E26.0 Primary hyperaldosteronism
0.001 0.970 0.029
E66 Obesity
0.000 0.970 0.030
S02.2 Fracture of nasal bones
0.000 0.970 0.030
S02.81 Fractures of other skull and facial bones (open)
0.000 0.971 0.029
S02.01 Fracture of vault of skull (open)
0.000 0.971 0.029
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.971 0.028
E23.1 Drug-induced hypopituitarism
0.000 0.971 0.028
S02.60 Fracture of mandible (closed)
0.000 0.971 0.029
E11.4 With neurological complications
0.000 0.971 0.028
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.972 0.028
S02.50 Fracture of tooth (closed)
0.000 0.972 0.028
I83 Varicose veins of lower extremities
0.028 0.972 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.973 0.027
S02.31 Fracture of orbital floor (open)
0.000 0.973 0.027
S02.1 Fracture of base of skull
0.000 0.974 0.026
S02.61 Fracture of mandible (open)
0.000 0.974 0.026
S02.51 Fracture of tooth (open)
0.000 0.974 0.026
S02.21 Fracture of nasal bones (open)
0.000 0.976 0.024
S05 Injury of eye and orbit
0.000 0.977 0.023
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.977 0.023
E23.6 Other disorders of pituitary gland
0.000 0.978 0.022
K14 Diseases of tongue
0.000 0.978 0.022
E66.1 Drug-induced obesity
0.000 0.978 0.021
J98.1 Pulmonary collapse
0.021 0.979 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.979 0.021
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.979 0.021
S05.8 Other injuries of eye and orbit
0.000 0.979 0.021
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.979 0.020
K93.1 Megacolon in Chagas' disease
0.000 0.979 0.020
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.979 0.020
S00-S09 Injuries to the head
0.000 0.980 0.020
S02.11 Fracture of base of skull (open)
0.000 0.980 0.020
E27 Other disorders of adrenal gland
0.000 0.980 0.020
K14.6 Glossodynia
0.000 0.980 0.020
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.980 0.020
S05.1 Contusion of eyeball and orbital tissues
0.000 0.980 0.020
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.980 0.019
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.019 0.981 0.000
E66.0 Obesity due to excess calories
0.000 0.983 0.017
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.983 0.017
E23.2 Diabetes insipidus
0.000 0.983 0.016
K14.1 Geographic tongue
0.000 0.983 0.017
S05.7 Avulsion of eye
0.000 0.983 0.017
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.983 0.017
K14.3 Hypertrophy of tongue papillae
0.000 0.983 0.017
K14.5 Plicated tongue
0.000 0.984 0.016
K14.4 Atrophy of tongue papillae
0.000 0.984 0.016
S08 Traumatic amputation of part of head
0.000 0.984 0.015
K14.0 Glossitis
0.000 0.985 0.015
S07 Crushing injury of head
0.000 0.985 0.015
S04 Injury of cranial nerves
0.000 0.985 0.015
I83.0 Varicose veins of lower extremities with ulcer
0.015 0.985 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.985 0.014
E27.0 Other adrenocortical overactivity
0.000 0.985 0.014
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.985 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.985 0.014
E27.1 Primary adrenocortical insufficiency
0.000 0.985 0.014
K14.2 Median rhomboid glossitis
0.000 0.986 0.014
S00 Superficial injury of head
0.000 0.986 0.014
S05.9 Injury of eye and orbit, part unspecified
0.000 0.986 0.014
E83.5 Disorders of calcium metabolism
0.014 0.986 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.986 0.014
C20 Malignant neoplasm of rectum
0.000 0.986 0.014
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.987 0.013
E27.9 Disorder of adrenal gland, unspecified
0.000 0.987 0.012
C15-C26 Malignant neoplasms of digestive organs
0.000 0.987 0.013
S00.4 Superficial injury of ear
0.000 0.988 0.012
S08.1 Traumatic amputation of ear
0.000 0.988 0.012
S02.20 Fracture of nasal bones (closed)
0.000 0.988 0.012
E27.2 Addisonian crisis
0.000 0.988 0.011
S00.7 Multiple superficial injuries of head
0.000 0.988 0.011
E70-E90 Metabolic disorders
0.002 0.988 0.009
S08.9 Traumatic amputation of unspecified part of head
0.000 0.989 0.011
S08.8 Traumatic amputation of other parts of head
0.000 0.989 0.011
S08.0 Avulsion of scalp
0.000 0.989 0.011
S00.0 Superficial injury of scalp
0.000 0.989 0.011
C15 Malignant neoplasm of oesophagus
0.000 0.989 0.011
C25 Malignant neoplasm of pancreas
0.000 0.989 0.011
S04.9 Injury of unspecified cranial nerve
0.000 0.989 0.011
S04.8 Injury of other cranial nerves
0.000 0.989 0.011
S04.7 Injury of accessory nerve
0.000 0.989 0.011
S04.6 Injury of acoustic nerve
0.000 0.989 0.011
S04.5 Injury of facial nerve
0.000 0.989 0.011
S04.4 Injury of abducent nerve
0.000 0.989 0.011
S04.3 Injury of trigeminal nerve
0.000 0.989 0.011
S04.2 Injury of trochlear nerve
0.000 0.989 0.011
S04.1 Injury of oculomotor nerve
0.000 0.989 0.011
S04.0 Injury of optic nerve and pathways
0.000 0.989 0.011
S07.9 Crushing injury of head, part unspecified
0.000 0.989 0.011
S07.8 Crushing injury of other parts of head
0.000 0.989 0.011
S07.1 Crushing injury of skull
0.000 0.989 0.011
S07.0 Crushing injury of face
0.000 0.989 0.011
S00.1 Contusion of eyelid and periocular area
0.000 0.989 0.011
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.989 0.010
C25.1 Body of pancreas
0.000 0.990 0.010
E23.0 Hypopituitarism
0.000 0.990 0.010
S09 Other and unspecified injuries of head
0.000 0.990 0.010
C15.5 Lower third of oesophagus
0.000 0.990 0.010
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.990 0.010
S02.10 Fracture of base of skull (closed)
0.000 0.990 0.010
S03.0 Dislocation of jaw
0.000 0.990 0.009
C25.3 Pancreatic duct
0.000 0.990 0.010
C25.2 Tail of pancreas
0.000 0.990 0.010
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.990 0.009
S03.4 Sprain and strain of jaw
0.000 0.990 0.009
S03.3 Dislocation of other and unspecified parts of head
0.000 0.990 0.009
S00.5 Superficial injury of lip and oral cavity
0.000 0.991 0.009
S06 Intracranial injury
0.000 0.991 0.009
C15.4 Middle third of oesophagus
0.000 0.991 0.009
C24.0 Extrahepatic bile duct
0.000 0.991 0.009
I77.6 Arteritis, unspecified
0.000 0.991 0.009
C17.0 Duodenum
0.000 0.991 0.009
C17 Malignant neoplasm of small intestine
0.000 0.991 0.009
E27.8 Other specified disorders of adrenal gland
0.000 0.991 0.009
S09.8 Other specified injuries of head
0.000 0.991 0.009
C25.8 Overlapping lesion of pancreas
0.000 0.991 0.009
C25.4 Endocrine pancreas
0.000 0.991 0.009
S03.1 Dislocation of septal cartilage of nose
0.000 0.991 0.008
E77 Disorders of glycoprotein metabolism
0.002 0.991 0.007
E76 Disorders of glycosaminoglycan metabolism
0.002 0.991 0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.991 0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.991 0.007
E73 Lactose intolerance
0.001 0.991 0.007
E74 Other disorders of carbohydrate metabolism
0.001 0.992 0.007
C15.0 Cervical part of oesophagus
0.000 0.992 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.992 0.007
S03.2 Dislocation of tooth
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.002 0.992 0.007
C15.8 Overlapping lesion of oesophagus
0.000 0.992 0.008
C15.2 Abdominal part of oesophagus
0.000 0.992 0.008
C15.1 Thoracic part of oesophagus
0.000 0.992 0.008
E72 Other disorders of amino-acid metabolism
0.002 0.992 0.006
E79 Disorders of purine and pyrimidine metabolism
0.002 0.992 0.006
E04.1 Non-toxic single thyroid nodule
0.001 0.992 0.007
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.992 0.008
E84 Cystic fibrosis
0.002 0.992 0.006
E85 Amyloidosis
0.002 0.992 0.006
C15.3 Upper third of oesophagus
0.000 0.992 0.008
E78.2 Mixed hyperlipidaemia
0.000 0.992 0.008
S00.3 Superficial injury of nose
0.000 0.992 0.008
C25.7 Other parts of pancreas
0.000 0.992 0.007
S09.7 Multiple injuries of head
0.000 0.992 0.007
S09.1 Injury of muscle and tendon of head
0.000 0.992 0.007
I77 Other disorders of arteries and arterioles
0.000 0.992 0.008
C24.9 Biliary tract, unspecified
0.000 0.992 0.007
S06.8 Other intracranial injuries
0.000 0.993 0.007
C24.8 Overlapping lesion of biliary tract
0.000 0.993 0.007
E88 Other metabolic disorders
0.001 0.993 0.007
K14.9 Disease of tongue, unspecified
0.000 0.993 0.007
I77.8 Other specified disorders of arteries and arterioles
0.000 0.993 0.007
S06.1 Traumatic cerebral oedema
0.000 0.993 0.007
C15.9 Oesophagus, unspecified
0.000 0.993 0.007
S06.2 Diffuse brain injury
0.000 0.993 0.007
S09.2 Traumatic rupture of ear drum
0.000 0.993 0.007
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.993 0.007
S06.4 Epidural haemorrhage
0.000 0.993 0.007
S06.9 Intracranial injury, unspecified
0.000 0.993 0.007
S06.7 Intracranial injury with prolonged coma
0.000 0.993 0.007
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.993 0.007
C17.8 Overlapping lesion of small intestine
0.000 0.993 0.007
C17.3 Meckel's diverticulum
0.000 0.993 0.007
I83.1 Varicose veins of lower extremities with inflammation
0.006 0.994 0.000
E78.6 Lipoprotein deficiency
0.000 0.994 0.006
E71.3 Disorders of fatty-acid metabolism
0.001 0.994 0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.994 0.005
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.994 0.005
E71.0 Maple-syrup-urine disease
0.001 0.994 0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.994 0.005
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.994 0.005
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.994 0.005
E76.2 Other mucopolysaccharidoses
0.001 0.994 0.005
E76.1 Mucopolysaccharidosis, type II
0.001 0.994 0.005
E76.0 Mucopolysaccharidosis, type I
0.001 0.994 0.005
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.994 0.005
E77.8 Other disorders of glycoprotein metabolism
0.001 0.994 0.005
E77.1 Defects in glycoprotein degradation
0.001 0.994 0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.994 0.005
E73.8 Other lactose intolerance
0.001 0.994 0.005
E73.1 Secondary lactase deficiency
0.001 0.994 0.005
E73.0 Congenital lactase deficiency
0.001 0.994 0.005
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.994 0.006
E75.5 Other lipid storage disorders
0.001 0.994 0.005
E78.3 Hyperchylomicronaemia
0.000 0.994 0.006
E88.9 Metabolic disorder, unspecified
0.000 0.994 0.006
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.994 0.005
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.994 0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.994 0.005
E74.2 Disorders of galactose metabolism
0.001 0.994 0.005
E74.1 Disorders of fructose metabolism
0.001 0.994 0.005
E78.1 Pure hyperglyceridaemia
0.000 0.994 0.006
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.994 0.006
E73.9 Lactose intolerance, unspecified
0.001 0.994 0.006
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.001 0.994 0.005
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.994 0.005
E75.3 Sphingolipidosis, unspecified
0.001 0.994 0.005
E75.1 Other gangliosidosis
0.001 0.994 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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