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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9257805
log Bayes Factor = 191.753
Chromosome 6   position 29,346,329  (GRCh37) Explore rs9257805 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
K40 Inguinal hernia
0.000 0.000 1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
E03 Other hypothyroidism
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.001 0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.999 0.001 0.000
K44 Diaphragmatic hernia
0.000 0.001 0.999
K40-K46 Hernia
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.998 0.002 0.000
E83.1 Disorders of iron metabolism
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.002 0.998
E27.1 Primary adrenocortical insufficiency
0.997 0.003 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.996 0.004 0.000
E16.2 Hypoglycaemia, unspecified
0.996 0.004 0.000
M15-M19 Arthrosis
0.995 0.005 0.000
N40 Hyperplasia of prostate
0.000 0.006 0.994
D86 Sarcoidosis
0.994 0.006 0.000
E10.3 With ophthalmic complications
0.993 0.007 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.007 0.993
Chapter XI Diseases of the digestive system
0.692 0.007 0.301
H25-H28 Disorders of lens
0.993 0.007 0.000
C15-C26 Malignant neoplasms of digestive organs
0.991 0.009 0.000
H26 Other cataract
0.991 0.009 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.010 0.990
R39 Other symptoms and signs involving the urinary system
0.000 0.010 0.990
K90-K93 Other diseases of the digestive system
0.692 0.010 0.298
H26.9 Cataract, unspecified
0.988 0.012 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.988 0.012 0.000
M17 Gonarthrosis [arthrosis of knee]
0.986 0.014 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.985 0.015 0.000
D86.9 Sarcoidosis, unspecified
0.980 0.020 0.000
E10.2 With renal complications
0.980 0.020 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.980 0.020 0.000
E14.3 With ophthalmic complications
0.978 0.022 0.000
I73 Other peripheral vascular diseases
0.978 0.022 0.000
M18 Arthrosis of first carpometacarpal joint
0.976 0.024 0.000
E10.1 With ketoacidosis
0.976 0.024 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.974 0.026 0.000
K90 Intestinal malabsorption
0.961 0.027 0.012
I73.9 Peripheral vascular disease, unspecified
0.973 0.027 0.000
C85.1 B-cell lymphoma, unspecified
0.969 0.031 0.000
Chapter IX Diseases of the circulatory system
0.969 0.031 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.969 0.031 0.000
C25 Malignant neoplasm of pancreas
0.968 0.032 0.000
H43-H45 Disorders of vitreous body and globe
0.965 0.035 0.000
I74 Arterial embolism and thrombosis
0.965 0.035 0.000
M17.9 Gonarthrosis, unspecified
0.956 0.044 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.956 0.044 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.953 0.047 0.000
C18 Malignant neoplasm of colon
0.953 0.047 0.000
M65-M68 Disorders of synovium and tendon
0.948 0.052 0.000
M20.1 Hallux valgus (acquired)
0.000 0.052 0.948
E50-E64 Other nutritional deficiencies
0.947 0.053 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.947 0.053 0.000
I77 Other disorders of arteries and arterioles
0.938 0.062 0.000
L50-L54 Urticaria and erythema
0.936 0.064 0.000
M20 Acquired deformities of fingers and toes
0.000 0.066 0.934
E70-E90 Metabolic disorders
0.934 0.066 0.000
H05 Disorders of orbit
0.931 0.069 0.000
C18.9 Colon, unspecified
0.930 0.070 0.000
M31 Other necrotising vasculopathies
0.929 0.071 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.073 0.927
H43 Disorders of vitreous body
0.926 0.074 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.923 0.077 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.921 0.079 0.000
E10.4 With neurological complications
0.919 0.081 0.000
C25.9 Pancreas, unspecified
0.919 0.081 0.000
H26.4 After-cataract
0.917 0.083 0.000
D86.0 Sarcoidosis of lung
0.916 0.084 0.000
E78.5 Hyperlipidaemia, unspecified
0.915 0.085 0.000
M67 Other disorders of synovium and tendon
0.912 0.088 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.912 0.088 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.912 0.088 0.000
M17.1 Other primary gonarthrosis
0.910 0.090 0.000
M25 Other joint disorders, not elsewhere classified
0.910 0.090 0.000
M35.3 Polymyalgia rheumatica
0.907 0.093 0.000
I60-I69 Cerebrovascular diseases
0.905 0.095 0.000
M05-M14 Inflammatory polyarthropathies
0.902 0.098 0.000
H02 Other disorders of eyelid
0.902 0.098 0.000
I73.0 Raynaud's syndrome
0.901 0.099 0.000
R35 Polyuria
0.000 0.099 0.901
C81 Hodgkin's disease
0.901 0.099 0.000
N40-N51 Diseases of male genital organs
0.000 0.100 0.900
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.900 0.100 0.000
H43.1 Vitreous haemorrhage
0.900 0.100 0.000
L40-L45 Papulosquamous disorders
0.897 0.103 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.897 0.103 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.894 0.106 0.000
C15 Malignant neoplasm of oesophagus
0.894 0.106 0.000
L50 Urticaria
0.894 0.106 0.000
Q50-Q56 Congenital malformations of genital organs
0.891 0.109 0.000
C04 Malignant neoplasm of floor of mouth
0.886 0.114 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.886 0.114 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.886 0.114 0.000
E14.9 Without complications
0.882 0.118 0.000
N42 Other disorders of prostate
0.000 0.119 0.881
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.879 0.121 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.879 0.121 0.000
M34 Systemic sclerosis
0.877 0.123 0.000
M24 Other specific joint derangements
0.874 0.126 0.000
M25.9 Joint disorder, unspecified
0.874 0.126 0.000
M67.8 Other specified disorders of synovium and tendon
0.873 0.127 0.000
H02.5 Other disorders affecting eyelid function
0.869 0.131 0.000
I77.1 Stricture of artery
0.869 0.131 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.864 0.136 0.000
M25.4 Effusion of joint
0.863 0.137 0.000
K90.9 Intestinal malabsorption, unspecified
0.859 0.137 0.004
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.862 0.138 0.000
D61 Other aplastic anaemias
0.862 0.138 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.859 0.141 0.000
H05.0 Acute inflammation of orbit
0.853 0.147 0.000
M31.6 Other giant cell arteritis
0.852 0.148 0.000
C25.3 Pancreatic duct
0.846 0.154 0.000
L43 Lichen planus
0.846 0.154 0.000
D00-D09 In situ neoplasms
0.846 0.154 0.000
D83 Common variable immunodeficiency
0.843 0.157 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.843 0.157 0.000
Chapter VI Diseases of the nervous system
0.842 0.158 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.842 0.158 0.000
M22 Disorders of patella
0.841 0.159 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.839 0.161 0.000
E61 Deficiency of other nutrient elements
0.838 0.162 0.000
E20 Hypoparathyroidism
0.836 0.163 0.000
L52 Erythema nodosum
0.835 0.165 0.000
M07 Psoriatic and enteropathic arthropathies
0.832 0.168 0.000
E53 Deficiency of other B group vitamins
0.830 0.170 0.000
Q43 Other congenital malformations of intestine
0.829 0.171 0.000
D50-D53 Nutritional anaemias
0.829 0.171 0.000
H27 Other disorders of lens
0.827 0.173 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.826 0.174 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.825 0.175 0.000
H30-H36 Disorders of choroid and retina
0.823 0.177 0.000
N48 Other disorders of penis
0.000 0.179 0.821
L50.9 Urticaria, unspecified
0.820 0.180 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.820 0.180 0.000
H02.3 Blepharochalasis
0.819 0.181 0.000
I65.2 Occlusion and stenosis of carotid artery
0.819 0.181 0.000
C34 Malignant neoplasm of bronchus and lung
0.819 0.181 0.000
C07 Malignant neoplasm of parotid gland
0.818 0.181 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.817 0.183 0.000
L43.9 Lichen planus, unspecified
0.813 0.187 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.811 0.189 0.000
C13 Malignant neoplasm of hypopharynx
0.810 0.190 0.000
G35 Multiple sclerosis
0.809 0.191 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.191 0.809
C02 Malignant neoplasm of other and unspecified parts of tongue
0.808 0.192 0.000
R33 Retention of urine
0.000 0.193 0.807
E14.8 With unspecified complications
0.806 0.194 0.000
C43 Malignant melanoma of skin
0.806 0.194 0.000
K46 Unspecified abdominal hernia
0.000 0.195 0.805
H02.0 Entropion and trichiasis of eyelid
0.805 0.195 0.000
M60-M63 Disorders of muscles
0.804 0.196 0.000
I74.8 Embolism and thrombosis of other arteries
0.803 0.197 0.000
D80 Immunodeficiency with predominantly antibody defects
0.802 0.198 0.000
N48.1 Balanoposthitis
0.000 0.198 0.802
C18.4 Transverse colon
0.801 0.199 0.000
E78.6 Lipoprotein deficiency
0.801 0.199 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.797 0.203 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.794 0.205 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.794 0.206 0.000
I77.6 Arteritis, unspecified
0.794 0.206 0.000
R30 Pain associated with micturition
0.000 0.206 0.794
I63 Cerebral infarction
0.792 0.208 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.791 0.209 0.000
M17.0 Primary gonarthrosis, bilateral
0.790 0.210 0.000
H36 Retinal disorders in diseases classified elsewhere
0.790 0.210 0.000
K50-K52 Noninfective enteritis and colitis
0.281 0.210 0.509
H44 Disorders of globe
0.790 0.210 0.000
E10.7 With multiple complications
0.789 0.211 0.000
C04.0 Anterior floor of mouth
0.788 0.212 0.000
E24 Cushing's syndrome
0.788 0.212 0.000
D86.8 Sarcoidosis of other and combined sites
0.788 0.212 0.000
M11 Other crystal arthropathies
0.787 0.213 0.000
N41 Inflammatory diseases of prostate
0.000 0.214 0.786
D06 Carcinoma in situ of cervix uteri
0.785 0.215 0.000
M70-M79 Other soft tissue disorders
0.785 0.215 0.000
M07.3 Other psoriatic arthropathies
0.782 0.218 0.000
H05.2 Exophthalmic conditions
0.782 0.218 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.219 0.781
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.775 0.219 0.006
H06.2 Dysthyroid exophthalmos
0.781 0.219 0.000
M32 Systemic lupus erythematosus
0.778 0.221 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.778 0.222 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.778 0.222 0.000
M72 Fibroblastic disorders
0.778 0.222 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.777 0.223 0.000
C91 Lymphoid leukaemia
0.777 0.223 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.776 0.224 0.000
C01 Malignant neoplasm of base of tongue
0.776 0.224 0.000
E10.5 With peripheral circulatory complications
0.776 0.224 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.775 0.225 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.773 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.773 0.227 0.000
E06 Thyroiditis
0.773 0.227 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.228 0.772
E13 Other specified diabetes mellitus
0.772 0.228 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.772 0.228 0.000
H05.8 Other disorders of orbit
0.771 0.229 0.000
L10-L14 Bullous disorders
0.770 0.230 0.000
M15 Polyarthrosis
0.770 0.230 0.000
M10 Gout
0.769 0.231 0.000
E10.0 With coma
0.768 0.232 0.000
H36.0 Diabetic retinopathy
0.767 0.233 0.000
C25.1 Body of pancreas
0.767 0.233 0.000
C18.3 Hepatic flexure
0.767 0.233 0.000
Q44.6 Cystic disease of liver
0.767 0.233 0.000
E14.4 With neurological complications
0.767 0.233 0.000
E10.6 With other specified complications
0.766 0.234 0.000
N48.4 Impotence of organic origin
0.000 0.235 0.765
C83 Diffuse non-Hodgkin's lymphoma
0.763 0.237 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.762 0.238 0.000
E23 Hypofunction and other disorders of pituitary gland
0.762 0.238 0.000
Q44.5 Other congenital malformations of bile ducts
0.762 0.238 0.000
C23 Malignant neoplasm of gallbladder
0.760 0.240 0.000
D50 Iron deficiency anaemia
0.760 0.240 0.000
D55-D59 Haemolytic anaemias
0.759 0.241 0.000
C15.4 Middle third of oesophagus
0.759 0.241 0.000
C84.5 Other and unspecified T-cell lymphomas
0.758 0.242 0.000
D61.9 Aplastic anaemia, unspecified
0.758 0.242 0.000
L94 Other localised connective tissue disorders
0.758 0.242 0.000
E27.9 Disorder of adrenal gland, unspecified
0.757 0.243 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.757 0.243 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.756 0.244 0.000
H26.1 Traumatic cataract
0.755 0.245 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.755 0.245 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.755 0.245 0.000
C34.3 Lower lobe, bronchus or lung
0.755 0.245 0.000
C03 Malignant neoplasm of gum
0.754 0.246 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.754 0.246 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.753 0.247 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.753 0.247 0.000
E21.0 Primary hyperparathyroidism
0.753 0.247 0.000
E53.8 Deficiency of other specified B group vitamins
0.753 0.247 0.000
E61.1 Iron deficiency
0.752 0.248 0.000
H02.6 Xanthelasma of eyelid
0.752 0.248 0.000
C16 Malignant neoplasm of stomach
0.752 0.248 0.000
E21.3 Hyperparathyroidism, unspecified
0.752 0.248 0.000
Q40 Other congenital malformations of upper alimentary tract
0.751 0.249 0.000
C25.2 Tail of pancreas
0.750 0.249 0.000
M23 Internal derangement of knee
0.749 0.251 0.000
H02.1 Ectropion of eyelid
0.749 0.251 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.252 0.748
N42.8 Other specified disorders of prostate
0.000 0.252 0.748
E14.2 Withrenal complications
0.748 0.252 0.000
M25.46 Effusion of joint (Lower leg)
0.746 0.254 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.255 0.745
C81.9 Hodgkin's disease, unspecified
0.744 0.256 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.743 0.257 0.000
L53 Other erythematous conditions
0.743 0.257 0.000
E14.1 With ketoacidosis
0.742 0.258 0.000
D06.9 Cervix, unspecified
0.742 0.258 0.000
Q45 Other congenital malformations of digestive system
0.741 0.259 0.000
L50.0 Allergic urticaria
0.740 0.260 0.000
D84 Other immunodeficiencies
0.736 0.264 0.000
C05 Malignant neoplasm of palate
0.735 0.265 0.000
I62 Other nontraumatic intracranial haemorrhage
0.735 0.265 0.000
M25.47 Effusion of joint (Ankle and foot)
0.735 0.265 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.735 0.265 0.000
I70 Atherosclerosis
0.734 0.265 0.000
M17.3 Other posttraumatic gonarthrosis
0.734 0.266 0.000
E78.1 Pure hyperglyceridaemia
0.734 0.266 0.000
M67.0 Short Achilles tendon (acquired)
0.733 0.267 0.000
M22.3 Other derangements of patella
0.733 0.267 0.000
D83.9 Common variable immunodeficiency, unspecified
0.732 0.268 0.000
Q74 Other congenital malformations of limb(s)
0.731 0.269 0.000
M25.42 Effusion of joint (Upper arm)
0.730 0.270 0.000
H53-H54 Visual disturbances and blindness
0.730 0.270 0.000
Q53 Undescended testicle
0.729 0.271 0.000
C95 Leukaemia of unspecified cell type
0.729 0.271 0.000
D50.8 Other iron deficiency anaemias
0.727 0.273 0.000
H43.9 Disorder of vitreous body, unspecified
0.726 0.273 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.275 0.725
D04 Carcinoma in situ of skin
0.725 0.275 0.000
M34.1 CR(E)ST syndrome
0.724 0.276 0.000
C04.9 Floor of mouth, unspecified
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.724 0.276 0.000
M35.1 Other overlap syndromes
0.723 0.277 0.000
E29 Testicular dysfunction
0.723 0.277 0.000
C15.3 Upper third of oesophagus
0.723 0.277 0.000
E51 Thiamine deficiency
0.723 0.277 0.000
L93 Lupus erythematosus
0.723 0.277 0.000
K90.8 Other intestinal malabsorption
0.714 0.278 0.008
H46 Optic neuritis
0.722 0.278 0.000
E27.2 Addisonian crisis
0.720 0.280 0.000
E20.9 Hypoparathyroidism, unspecified
0.720 0.280 0.000
M12 Other specific arthropathies
0.720 0.280 0.000
H43.2 Crystalline deposits in vitreous body
0.719 0.281 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.718 0.282 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
C15.0 Cervical part of oesophagus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.283 0.717
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.283 0.717
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
M35.2 Behcet's disease
0.717 0.283 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
C81.2 Mixed cellularity
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C93 Monocytic leukaemia
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.283 0.716
M24.2 Disorder of ligament
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.283 0.000
E32 Diseases of thymus
0.716 0.283 0.000
E31 Polyglandular dysfunction
0.716 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.283 0.000
E25 Adrenogenital disorders
0.716 0.283 0.000
C85.0 Lymphosarcoma
0.716 0.284 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.284 0.716
R30.0 Dysuria
0.000 0.284 0.716
D82 Immunodeficiency associated with other major defects
0.716 0.284 0.000
D81 Combined immunodeficiencies
0.716 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.716 0.284 0.000
E27.0 Other adrenocortical overactivity
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.715 0.285 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.714 0.286 0.000
M66 Spontaneous rupture of synovium and tendon
0.714 0.286 0.000
E14.7 With multiple complications
0.714 0.286 0.000
E14.6 With other specified complications
0.714 0.286 0.000
E14.5 With peripheral circulatory complications
0.714 0.286 0.000
E14.0 With coma
0.714 0.286 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.714 0.286 0.000
Q76 Congenital malformations of spine and bony thorax
0.714 0.286 0.000
Q39 Congenital malformations of oesophagus
0.713 0.287 0.000
E78.4 Other hyperlipidaemia
0.713 0.287 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.712 0.287 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.288 0.000
C88 Malignant immunoproliferative diseases
0.712 0.288 0.000
E07 Other disorders of thyroid
0.711 0.289 0.000
K70-K77 Diseases of liver
0.705 0.289 0.006
M25.97 Joint disorder, unspecified (Ankle and foot)
0.711 0.289 0.000
K75.4 Autoimmune hepatitis
0.711 0.289 0.000
E16.1 Other hypoglycaemia
0.711 0.289 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
C81.0 Lymphocytic predominance
0.710 0.289 0.000
H26.3 Drug-induced cataract
0.710 0.290 0.000
R39.2 Extrarenal uraemia
0.000 0.290 0.710
K93 Disorders of other digestive organs in diseases classified elsewhere
0.496 0.290 0.214
K75 Other inflammatory liver diseases
0.708 0.291 0.001
L50.1 Idiopathic urticaria
0.708 0.292 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.707 0.293 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.707 0.293 0.000
M34.9 Systemic sclerosis, unspecified
0.707 0.293 0.000
D86.3 Sarcoidosis of skin
0.707 0.293 0.000
M80-M85 Disorders of bone density and structure
0.707 0.293 0.000
Q35-Q37 Cleft lip and cleft palate
0.706 0.294 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.706 0.294 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
N42.2 Atrophy of prostate
0.000 0.294 0.706
C18.0 Caecum
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
M11.2 Other chondrocalcinosis
0.704 0.296 0.000
Q66 Congenital deformities of feet
0.704 0.296 0.000
E28 Ovarian dysfunction
0.703 0.297 0.000
C02.9 Tongue, unspecified
0.702 0.298 0.000
L40 Psoriasis
0.701 0.299 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.701 0.299 0.000
K41 Femoral hernia
0.000 0.299 0.701
I60 Subarachnoid haemorrhage
0.700 0.300 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.700 0.300 0.000
E83 Disorders of mineral metabolism
0.531 0.300 0.169
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.700 0.300 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.700 0.300 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.700 0.300 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.700 0.300 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.699 0.301 0.000
E73 Lactose intolerance
0.699 0.301 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.698 0.302 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.698 0.302 0.000
C00 Malignant neoplasm of lip
0.698 0.302 0.000
K90.3 Pancreatic steatorrhoea
0.689 0.302 0.009
K90.2 Blind loop syndrome, not elsewhere classified
0.689 0.302 0.009
K90.1 Tropical sprue
0.689 0.302 0.009
M25.96 Joint disorder, unspecified (Lower leg)
0.698 0.302 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.697 0.303 0.000
C11 Malignant neoplasm of nasopharynx
0.696 0.304 0.000
M22.2 Patellofemoral disorders
0.696 0.304 0.000
M00-M03 Infectious arthropathies
0.696 0.304 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.695 0.305 0.000
E55 Vitamin D deficiency
0.694 0.306 0.000
C25.8 Overlapping lesion of pancreas
0.694 0.306 0.000
C25.7 Other parts of pancreas
0.694 0.306 0.000
C25.4 Endocrine pancreas
0.694 0.306 0.000
Q43.8 Other specified congenital malformations of intestine
0.694 0.306 0.000
C84.0 Mycosis fungoides
0.693 0.307 0.000
C18.1 Appendix
0.693 0.307 0.000
H47.2 Optic atrophy
0.692 0.308 0.000
E03.8 Other specified hypothyroidism
0.692 0.308 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.692 0.308 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.692 0.308 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
E80.4 Gilbert's syndrome
0.689 0.311 0.000
Q51 Congenital malformations of uterus and cervix
0.688 0.312 0.000
M35.7 Hypermobility syndrome
0.687 0.313 0.000
C81.1 Nodular sclerosis
0.686 0.314 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.685 0.314 0.000
G30-G32 Other degenerative diseases of the nervous system
0.685 0.315 0.000
E78.2 Mixed hyperlipidaemia
0.685 0.315 0.000
C38.4 Pleura
0.685 0.315 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.684 0.316 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.684 0.316 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.684 0.316 0.000
Q52 Other congenital malformations of female genitalia
0.684 0.316 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.683 0.317 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.683 0.317 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.319 0.681
Q65 Congenital deformities of hip
0.680 0.320 0.000
M67.4 Ganglion
0.680 0.320 0.000
C18.6 Descending colon
0.680 0.320 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.680 0.320 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.680 0.320 0.000
C83.3 Large cell (diffuse)
0.679 0.321 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.679 0.321 0.000
E63 Other nutritional deficiencies
0.679 0.321 0.000
E56 Other vitamin deficiencies
0.679 0.321 0.000
E50 Vitamin A deficiency
0.679 0.321 0.000
E60 Dietary zinc deficiency
0.679 0.321 0.000
E59 Dietary selenium deficiency
0.679 0.321 0.000
E58 Dietary calcium deficiency
0.679 0.321 0.000
E54 Ascorbic acid deficiency
0.679 0.321 0.000
E52 Niacin deficiency [pellagra]
0.679 0.321 0.000
I77.2 Rupture of artery
0.679 0.321 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.326 0.674
I77.5 Necrosis of artery
0.673 0.327 0.000
I77.4 Coeliac artery compression syndrome
0.673 0.327 0.000
I77.3 Arterial fibromuscular dysplasia
0.673 0.327 0.000
H47.3 Other disorders of optic disk
0.673 0.327 0.000
C13.0 Postcricoid region
0.672 0.328 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.672 0.328 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.672 0.328 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.672 0.328 0.000
L54 Erythema in diseases classified elsewhere
0.671 0.329 0.000
E05.8 Other thyrotoxicosis
0.670 0.330 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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