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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9257812
log Bayes Factor = 50.7359
Chromosome 6   position 29,357,021  (GRCh37) Explore rs9257812 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E27 Other disorders of adrenal gland
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
E10.2 With renal complications
0.000 0.012 0.988
E27.1 Primary adrenocortical insufficiency
0.000 0.012 0.988
E14 Unspecified diabetes mellitus
0.000 0.049 0.951
E13 Other specified diabetes mellitus
0.000 0.050 0.950
E24 Cushing's syndrome
0.000 0.051 0.949
E10.1 With ketoacidosis
0.000 0.069 0.931
E10.4 With neurological complications
0.000 0.078 0.922
L40.9 Psoriasis, unspecified
0.919 0.081 0.000
E13.9 Without complications
0.000 0.086 0.914
E23 Hypofunction and other disorders of pituitary gland
0.000 0.092 0.908
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.097 0.903
E14.3 With ophthalmic complications
0.000 0.097 0.903
E50-E64 Other nutritional deficiencies
0.000 0.119 0.881
E20 Hypoparathyroidism
0.000 0.124 0.876
E24.0 Pituitary-dependent Cushing's disease
0.000 0.145 0.854
E23.0 Hypopituitarism
0.000 0.155 0.845
E03 Other hypothyroidism
0.000 0.171 0.829
E24.9 Cushing's syndrome, unspecified
0.000 0.178 0.822
E05.8 Other thyrotoxicosis
0.000 0.184 0.816
E29 Testicular dysfunction
0.000 0.199 0.800
E14.6 With other specified complications
0.000 0.205 0.795
E22 Hyperfunction of pituitary gland
0.000 0.206 0.794
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.207 0.793
E20.9 Hypoparathyroidism, unspecified
0.000 0.213 0.787
E10.0 With coma
0.000 0.219 0.781
L40 Psoriasis
0.781 0.219 0.000
E55 Vitamin D deficiency
0.000 0.227 0.773
E53 Deficiency of other B group vitamins
0.000 0.241 0.759
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.242 0.758
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.250 0.750
E10.7 With multiple complications
0.000 0.255 0.745
E23.2 Diabetes insipidus
0.000 0.259 0.741
E14.2 Withrenal complications
0.000 0.260 0.740
E24.2 Drug-induced Cushing's syndrome
0.000 0.271 0.729
E53.9 Vitamin B deficiency, unspecified
0.000 0.272 0.728
E51 Thiamine deficiency
0.000 0.273 0.727
E03.9 Hypothyroidism, unspecified
0.000 0.279 0.721
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.716
E32 Diseases of thymus
0.000 0.283 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.286 0.713
E27.0 Other adrenocortical overactivity
0.000 0.286 0.713
L40.5 Arthropathic psoriasis
0.712 0.288 0.000
E40-E46 Malnutrition
0.000 0.295 0.705
E14.5 With peripheral circulatory complications
0.000 0.296 0.703
E25 Adrenogenital disorders
0.000 0.299 0.701
E55.9 Vitamin D deficiency, unspecified
0.000 0.303 0.697
E27.9 Disorder of adrenal gland, unspecified
0.000 0.306 0.694
E27.8 Other specified disorders of adrenal gland
0.000 0.308 0.691
E10.6 With other specified complications
0.000 0.315 0.685
E10.8 With unspecified complications
0.000 0.315 0.685
E14.7 With multiple complications
0.000 0.318 0.682
E14.0 With coma
0.000 0.318 0.682
E22.0 Acromegaly and pituitary gigantism
0.000 0.318 0.682
E13.8 With unspecified complications
0.000 0.319 0.681
E13.7 With multiple complications
0.000 0.319 0.681
E13.6 With other specified complications
0.000 0.319 0.681
E13.5 With peripheral circulatory complications
0.000 0.319 0.681
E13.4 With neurological complications
0.000 0.319 0.681
E13.2 With renal complications
0.000 0.319 0.681
E13.1 With ketoacidosis
0.000 0.319 0.681
E13.0 With coma
0.000 0.319 0.681
E31 Polyglandular dysfunction
0.000 0.319 0.681
E24.8 Other Cushing's syndrome
0.000 0.320 0.680
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.320 0.680
E24.3 Ectopic ACTH syndrome
0.000 0.320 0.680
E24.1 Nelson's syndrome
0.000 0.320 0.680
E13.3 With ophthalmic complications
0.000 0.322 0.678
E14.1 With ketoacidosis
0.000 0.337 0.663
E14.8 With unspecified complications
0.000 0.339 0.661
E06 Thyroiditis
0.000 0.339 0.661
E29.1 Testicular hypofunction
0.000 0.342 0.658
K90 Intestinal malabsorption
0.000 0.346 0.654
E28 Ovarian dysfunction
0.000 0.348 0.652
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.349 0.651
E23.1 Drug-induced hypopituitarism
0.000 0.349 0.651
L40.8 Other psoriasis
0.651 0.349 0.000
E10.5 With peripheral circulatory complications
0.000 0.352 0.648
L40.0 Psoriasis vulgaris
0.645 0.355 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.643
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.361 0.639
E14.4 With neurological complications
0.000 0.368 0.632
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.368 0.631
E50 Vitamin A deficiency
0.000 0.368 0.631
E60 Dietary zinc deficiency
0.000 0.368 0.631
E59 Dietary selenium deficiency
0.000 0.368 0.631
E52 Niacin deficiency [pellagra]
0.000 0.368 0.631
E20.8 Other hypoparathyroidism
0.000 0.372 0.628
E20.1 Pseudohypoparathyroidism
0.000 0.372 0.628
E20.0 Idiopathic hypoparathyroidism
0.000 0.372 0.628
E61 Deficiency of other nutrient elements
0.000 0.374 0.626
E23.7 Disorder of pituitary gland, unspecified
0.000 0.375 0.624
E51.2 Wernicke's encephalopathy
0.000 0.383 0.616
E03.1 Congenital hypothyroidism without goitre
0.000 0.389 0.611
E14.9 Without complications
0.000 0.390 0.610
E22.1 Hyperprolactinaemia
0.000 0.396 0.604
E26 Hyperaldosteronism
0.000 0.405 0.595
E03.5 Myxoedema coma
0.000 0.405 0.594
E03.4 Atrophy of thyroid (acquired)
0.000 0.405 0.594
E03.3 Postinfectious hypothyroidism
0.000 0.405 0.594
E56 Other vitamin deficiencies
0.000 0.410 0.590
E27.2 Addisonian crisis
0.000 0.413 0.587
E58 Dietary calcium deficiency
0.000 0.414 0.586
E16 Other disorders of pancreatic internal secretion
0.000 0.416 0.584
E29.9 Testicular dysfunction, unspecified
0.000 0.426 0.574
E29.8 Other testicular dysfunction
0.000 0.426 0.574
E29.0 Testicular hyperfunction
0.000 0.426 0.574
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.431 0.569
E22.8 Other hyperfunction of pituitary gland
0.000 0.431 0.569
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.431 0.569
L40.2 Acrodermatitis continua
0.560 0.440 0.000
E34 Other endocrine disorders
0.000 0.441 0.559
E55.0 Rickets, active
0.000 0.445 0.554
K90.9 Intestinal malabsorption, unspecified
0.000 0.452 0.548
L40.3 Pustulosis palmaris et plantaris
0.547 0.453 0.000
E07 Other disorders of thyroid
0.000 0.455 0.545
E63 Other nutritional deficiencies
0.000 0.456 0.544
E53.1 Pyridoxine deficiency
0.000 0.456 0.544
E53.0 Riboflavin deficiency
0.000 0.456 0.544
E15 Nondiabetic hypoglycaemic coma
0.000 0.457 0.543
L40.4 Guttate psoriasis
0.541 0.459 0.000
E23.6 Other disorders of pituitary gland
0.000 0.463 0.536
E54 Ascorbic acid deficiency
0.000 0.464 0.536
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.465 0.535
L40.1 Generalised pustular psoriasis
0.531 0.469 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.479 0.521
E51.8 Other manifestations of thiamine deficiency
0.000 0.479 0.521
E51.1 Beriberi
0.000 0.479 0.521
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E03.8 Other specified hypothyroidism
0.000 0.488 0.512
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.494 0.506
E45 Retarded development following protein-energy malnutrition
0.000 0.494 0.506
E43 Unspecified severe protein-energy malnutrition
0.000 0.494 0.506
E42 Marasmic kwashiorkor
0.000 0.494 0.506
E41 Nutritional marasmus
0.000 0.494 0.506
E40 Kwashiorkor
0.000 0.494 0.506
E25.9 Adrenogenital disorder, unspecified
0.000 0.497 0.502
E25.8 Other adrenogenital disorders
0.000 0.497 0.502
E46 Unspecified protein-energy malnutrition
0.000 0.506 0.494
E06.3 Autoimmune thyroiditis
0.000 0.512 0.488
E31.9 Polyglandular dysfunction, unspecified
0.000 0.512 0.488
E31.8 Other polyglandular dysfunction
0.000 0.512 0.488
E31.1 Polyglandular hyperfunction
0.000 0.512 0.488
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.513 0.487
E06.9 Thyroiditis, unspecified
0.000 0.517 0.482
E16.1 Other hypoglycaemia
0.000 0.522 0.478
E61.2 Magnesium deficiency
0.000 0.523 0.477
E06.4 Drug-induced thyroiditis
0.000 0.526 0.474
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.526 0.474
E06.1 Subacute thyroiditis
0.000 0.526 0.474
E06.0 Acute thyroiditis
0.000 0.526 0.474
K90.3 Pancreatic steatorrhoea
0.000 0.531 0.469
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.531 0.469
K90.1 Tropical sprue
0.000 0.531 0.469
E28.9 Ovarian dysfunction, unspecified
0.000 0.532 0.467
E28.8 Other ovarian dysfunction
0.000 0.532 0.467
E28.1 Androgen excess
0.000 0.532 0.467
E28.0 Oestrogen excess
0.000 0.532 0.467
E28.2 Polycystic ovarian syndrome
0.000 0.536 0.464
E50.9 Vitamin A deficiency, unspecified
0.000 0.547 0.453
E50.8 Other manifestations of vitamin A deficiency
0.000 0.547 0.453
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.547 0.453
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.547 0.453
E50.5 Vitamin A deficiency with night blindness
0.000 0.547 0.453
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.547 0.453
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.547 0.453
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.547 0.453
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.547 0.453
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.547 0.453
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.547 0.453
E64.8 Sequelae of other nutritional deficiencies
0.000 0.547 0.453
E64.3 Sequelae of rickets
0.000 0.547 0.453
E64.2 Sequelae of vitamin C deficiency
0.000 0.547 0.453
E64.1 Sequelae of vitamin A deficiency
0.000 0.547 0.453
E64.0 Sequelae of protein-energy malnutrition
0.000 0.547 0.453
E31.0 Autoimmune polyglandular failure
0.000 0.547 0.452
K90.8 Other intestinal malabsorption
0.000 0.548 0.452
E61.9 Deficiency of nutrient element, unspecified
0.000 0.551 0.449
E61.8 Deficiency of other specified nutrient elements
0.000 0.551 0.449
E61.7 Deficiency of multiple nutrient elements
0.000 0.551 0.449
E61.6 Vanadium deficiency
0.000 0.551 0.449
E61.5 Molybdenum deficiency
0.000 0.551 0.449
E61.4 Chromium deficiency
0.000 0.551 0.449
E61.3 Manganese deficiency
0.000 0.551 0.449
E61.0 Copper deficiency
0.000 0.551 0.449
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.554 0.445
E26.9 Hyperaldosteronism, unspecified
0.000 0.557 0.442
E26.8 Other hyperaldosteronism
0.000 0.573 0.427
E26.1 Secondary hyperaldosteronism
0.000 0.573 0.427
E56.9 Vitamin deficiency, unspecified
0.000 0.577 0.423
E56.8 Deficiency of other vitamins
0.000 0.577 0.423
E56.0 Deficiency of vitamin E
0.000 0.577 0.423
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.581 0.419
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.581 0.419
E16.4 Abnormal secretion of gastrin
0.000 0.581 0.419
E16.3 Increased secretion of glucagon
0.000 0.581 0.419
E16.2 Hypoglycaemia, unspecified
0.000 0.590 0.410
E61.1 Iron deficiency
0.000 0.592 0.408
E28.3 Primary ovarian failure
0.000 0.592 0.407
E34.3 Short stature, not elsewhere classified
0.000 0.593 0.407
E34.5 Androgen resistance syndrome
0.000 0.599 0.401
E34.4 Constitutional tall stature
0.000 0.599 0.401
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.599 0.401
E34.1 Other hypersecretion of intestinal hormones
0.000 0.599 0.401
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.600 0.400
E07.1 Dyshormogenetic goitre
0.000 0.609 0.391
E07.0 Hypersecretion of calcitonin
0.000 0.609 0.391
E63.8 Other specified nutritional deficiencies
0.000 0.609 0.390
E63.1 Imbalance of constituents of food intake
0.000 0.609 0.390
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.609 0.390
E06.5 Other chronic thyroiditis
0.000 0.614 0.386
E56.1 Deficiency of vitamin K
0.000 0.618 0.382
E34.8 Other specified endocrine disorders
0.000 0.634 0.366
E44.1 Mild protein-energy malnutrition
0.000 0.637 0.363
E44.0 Moderate protein-energy malnutrition
0.000 0.637 0.363
E34.9 Endocrine disorder, unspecified
0.000 0.637 0.363
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.651 0.348
E34.0 Carcinoid syndrome
0.000 0.657 0.343
E07.9 Disorder of thyroid, unspecified
0.000 0.672 0.328
E07.8 Other specified disorders of thyroid
0.000 0.685 0.315
E63.9 Nutritional deficiency, unspecified
0.001 0.697 0.303
E26.0 Primary hyperaldosteronism
0.001 0.724 0.275
E65-E68 Obesity and other hyperalimentation
0.000 0.735 0.264
E67 Other hyperalimentation
0.000 0.810 0.190
E68 Sequelae of hyperalimentation
0.000 0.810 0.190
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.813 0.187
E53.8 Deficiency of other specified B group vitamins
0.000 0.850 0.150
E67.8 Other specified hyperalimentation
0.000 0.864 0.136
E67.3 Hypervitaminosis D
0.000 0.864 0.136
E67.2 Megavitamin-B6 syndrome
0.000 0.864 0.136
E67.1 Hypercarotenaemia
0.000 0.864 0.136
E67.0 Hypervitaminosis A
0.000 0.864 0.136
E21.4 Other specified disorders of parathyroid gland
0.000 0.866 0.134
E21.2 Other hyperparathyroidism
0.000 0.872 0.128
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.877 0.123
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.884 0.116
L40-L45 Papulosquamous disorders
0.115 0.885 0.001
E04 Other non-toxic goitre
0.001 0.896 0.103
E65 Localised adiposity
0.001 0.898 0.102
L44 Other papulosquamous disorders
0.082 0.917 0.001
L41 Parapsoriasis
0.082 0.917 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.082 0.917 0.001
E04.8 Other specified non-toxic goitre
0.001 0.925 0.074
M35.0 Sicca syndrome [Sjogren]
0.000 0.926 0.074
E04.9 Non-toxic goitre, unspecified
0.000 0.927 0.073
E21.3 Hyperparathyroidism, unspecified
0.000 0.927 0.073
E11 Non-insulin-dependent diabetes mellitus
0.000 0.932 0.068
E83 Disorders of mineral metabolism
0.063 0.936 0.001
L42 Pityriasis rosea
0.060 0.940 0.001
L41.9 Parapsoriasis, unspecified
0.059 0.940 0.001
L41.8 Other parapsoriasis
0.059 0.940 0.001
L41.5 Retiform parapsoriasis
0.059 0.940 0.001
L41.4 Large plaque parapsoriasis
0.059 0.940 0.001
L41.3 Small plaque parapsoriasis
0.059 0.940 0.001
L41.2 Lymphomatoid papulosis
0.059 0.940 0.001
L41.1 Pityriasis lichenoides chronica
0.059 0.940 0.001
L41.0 Pityriasis lichenoides et varioliformis acuta
0.059 0.940 0.001
L44.9 Papulosquamous disorder, unspecified
0.059 0.940 0.001
L44.8 Other specified papulosquamous disorders
0.059 0.940 0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.059 0.940 0.001
L44.3 Lichen ruber moniliformis
0.059 0.940 0.001
L44.2 Lichen striatus
0.059 0.940 0.001
L44.1 Lichen nitidus
0.059 0.940 0.001
L44.0 Pityriasis rubra pilaris
0.059 0.940 0.001
E11.9 Without complications
0.000 0.946 0.054
E11.6 With other specified complications
0.000 0.948 0.052
E11.2 With renal complications
0.000 0.949 0.051
E11.7 With multiple complications
0.000 0.951 0.049
E11.8 With unspecified complications
0.000 0.953 0.047
E83.8 Other disorders of mineral metabolism
0.046 0.954 0.001
E83.2 Disorders of zinc metabolism
0.046 0.954 0.001
E83.0 Disorders of copper metabolism
0.046 0.954 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.045 0.954 0.001
E04.0 Non-toxic diffuse goitre
0.001 0.954 0.045
K90-K93 Other diseases of the digestive system
0.000 0.959 0.041
E11.0 With coma
0.000 0.960 0.040
E83.3 Disorders of phosphorus metabolism
0.039 0.960 0.000
E21.0 Primary hyperparathyroidism
0.000 0.961 0.038
L43 Lichen planus
0.034 0.964 0.002
E11.1 With ketoacidosis
0.000 0.969 0.031
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.970 0.030
L43.3 Subacute (active) lichen planus
0.025 0.974 0.001
L43.2 Lichenoid drug reaction
0.025 0.974 0.001
L43.1 Bullous lichen planus
0.025 0.974 0.001
L43.0 Hypertrophic lichen planus
0.025 0.974 0.001
E11.5 With peripheral circulatory complications
0.000 0.977 0.023
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.978 0.022
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.978 0.021
K93.1 Megacolon in Chagas' disease
0.000 0.978 0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.978 0.021
E66 Obesity
0.000 0.978 0.021
L43.8 Other lichen planus
0.017 0.982 0.002
E83.4 Disorders of magnesium metabolism
0.018 0.982 0.001
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.016 0.984 0.000
E66.1 Drug-induced obesity
0.000 0.984 0.015
E66.0 Obesity due to excess calories
0.000 0.986 0.014
E11.4 With neurological complications
0.000 0.987 0.013
H26.9 Cataract, unspecified
0.000 0.987 0.013
M35 Other systemic involvement of connective tissue
0.000 0.987 0.013
E11.3 With ophthalmic complications
0.000 0.988 0.012
C50.3 Lower-inner quadrant of breast
0.000 0.988 0.012
H90 Conductive and sensorineural hearing loss
0.000 0.990 0.010
H90.3 Sensorineural hearing loss, bilateral
0.000 0.991 0.009
M35.8 Other specified systemic involvement of connective tissue
0.000 0.991 0.009
H90.2 Conductive hearing loss, unspecified
0.000 0.991 0.009
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.991 0.009
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.991 0.009
M35.5 Multifocal fibrosclerosis
0.000 0.991 0.009
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.991 0.009
E04.2 Non-toxic multinodular goitre
0.001 0.991 0.009
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.991 0.009
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.991 0.009
M35.2 Behcet's disease
0.000 0.991 0.009
H90.5 Sensorineural hearing loss, unspecified
0.000 0.991 0.009
E04.1 Non-toxic single thyroid nodule
0.001 0.991 0.008
M35.1 Other overlap syndromes
0.000 0.991 0.009
B97 Viral agents as the cause of diseases classified to other chapters
0.008 0.992 0.000
E83.5 Disorders of calcium metabolism
0.008 0.992 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.992 0.008
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.992 0.008
M35.7 Hypermobility syndrome
0.000 0.992 0.008
X41.9 Unspecified place
0.008 0.992 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.007 0.992 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.993 0.007
M22.2 Patellofemoral disorders
0.000 0.993 0.007
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.993 0.007
H26 Other cataract
0.000 0.994 0.006
H26.4 After-cataract
0.000 0.994 0.006
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
A87.9 Viral meningitis, unspecified
0.000 0.994 0.006
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.006 0.994 0.000
H26.1 Traumatic cataract
0.000 0.994 0.006
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.006 0.994 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.995 0.005
A08.4 Viral intestinal infection, unspecified
0.000 0.995 0.005
H26.2 Complicated cataract
0.000 0.995 0.005
H90.0 Conductive hearing loss, bilateral
0.000 0.995 0.005
S82.10 Fracture of upper end of tibia (closed)
0.000 0.995 0.005
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.995 0.005
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.005 0.995 0.000
E70-E90 Metabolic disorders
0.001 0.995 0.004
H26.3 Drug-induced cataract
0.000 0.995 0.005
L43.9 Lichen planus, unspecified
0.002 0.996 0.002
M34.1 CR(E)ST syndrome
0.000 0.996 0.004
E73 Lactose intolerance
0.000 0.996 0.004
M25.76 Osteophyte (Lower leg)
0.000 0.996 0.004
C77.4 Inguinal and lower limb lymph nodes
0.000 0.996 0.004
E79 Disorders of purine and pyrimidine metabolism
0.000 0.996 0.004
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.996 0.004
X41.0 Home
0.004 0.996 0.000
X41.8 Other specified place
0.004 0.996 0.000
X41.7 Farm
0.004 0.996 0.000
X41.6 Industrial and construction area
0.004 0.996 0.000
X41.5 Trade and service area
0.004 0.996 0.000
X41.4 Street and highway
0.004 0.996 0.000
X41.3 Sports and athletics area
0.004 0.996 0.000
X41.2 School, other institution and public administrative area
0.004 0.996 0.000
X41.1 Residential institution
0.004 0.996 0.000
K92 Other diseases of digestive system
0.002 0.996 0.002
M34 Systemic sclerosis
0.000 0.996 0.004
M22 Disorders of patella
0.000 0.996 0.004
E74 Other disorders of carbohydrate metabolism
0.000 0.996 0.003
E73.9 Lactose intolerance, unspecified
0.000 0.996 0.004
E70 Disorders of aromatic amino-acid metabolism
0.001 0.996 0.003
D47.4 Osteomyelofibrosis
0.000 0.996 0.004
E77 Disorders of glycoprotein metabolism
0.001 0.996 0.003
E76 Disorders of glycosaminoglycan metabolism
0.001 0.996 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.996 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.996 0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.996 0.004
M34.9 Systemic sclerosis, unspecified
0.000 0.996 0.004
A87 Viral meningitis
0.000 0.996 0.004
E85 Amyloidosis
0.000 0.996 0.003
E84 Cystic fibrosis
0.001 0.996 0.003
V18.0 Driver injured in nontraffic accident
0.004 0.996 0.000
E72 Other disorders of amino-acid metabolism
0.001 0.996 0.003
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.003
M34.8 Other forms of systemic sclerosis
0.000 0.997 0.003
M22.8 Other disorders of patella
0.000 0.997 0.003
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.997 0.003
M31.6 Other giant cell arteritis
0.000 0.997 0.003
M22.0 Recurrent dislocation of patella
0.000 0.997 0.003
E73.8 Other lactose intolerance
0.000 0.997 0.003
E73.1 Secondary lactase deficiency
0.000 0.997 0.003
E73.0 Congenital lactase deficiency
0.000 0.997 0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.997 0.003
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.997 0.003
R25.2 Cramp and spasm
0.000 0.997 0.003
V18 Pedal cyclist injured in noncollision transport accident
0.003 0.997 0.000
B02.2 Zoster with other nervous system involvement
0.000 0.997 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.997 0.003
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
E79.1 Lesch-Nyhan syndrome
0.000 0.997 0.003
H11.4 Other conjunctival vascular disorders and cysts
0.003 0.997 0.000
V17.4 Driver injured in traffic accident
0.003 0.997 0.000
L53.9 Erythematous condition, unspecified
0.003 0.997 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.997 0.003
C50.1 Central portion of breast
0.000 0.997 0.003
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
M22.9 Disorder of patella, unspecified
0.000 0.997 0.003
M22.1 Recurrent subluxation of patella
0.000 0.997 0.003
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities
0.003 0.997 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.997 0.003
E70.3 Albinism
0.000 0.997 0.003
E85.3 Secondary systemic amyloidosis
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.003
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.003
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.003
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.003
E70.0 Classical phenylketonuria
0.001 0.997 0.003
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.997 0.003
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.997 0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.997 0.003
E74.2 Disorders of galactose metabolism
0.000 0.997 0.003
E74.1 Disorders of fructose metabolism
0.000 0.997 0.003
E85.8 Other amyloidosis
0.000 0.997 0.003
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.997 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.997 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.997 0.002
E76.2 Other mucopolysaccharidoses
0.001 0.997 0.002
E76.1 Mucopolysaccharidosis, type II
0.001 0.997 0.002
E76.0 Mucopolysaccharidosis, type I
0.001 0.997 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.997 0.002
E77.8 Other disorders of glycoprotein metabolism
0.001 0.997 0.002
E77.1 Defects in glycoprotein degradation
0.001 0.997 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.997 0.002
K92.8 Other specified diseases of digestive system
0.002 0.997 0.001
M34.0 Progressive systemic sclerosis
0.000 0.997 0.003
A87.8 Other viral meningitis
0.000 0.997 0.003
A87.2 Lymphocytic choriomeningitis
0.000 0.997 0.003
A87.1 Adenoviral meningitis
0.000 0.997 0.003
A87.0 Enteroviral meningitis
0.000 0.997 0.003
X40-X49 Accidental poisoning by and exposure to noxious substances
0.003 0.997 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.997 0.003
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.997 0.003
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.997 0.003
V18.1 Passenger injured in nontraffic accident
0.003 0.997 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.997 0.003
K91.1 Postgastric surgery syndromes
0.000 0.997 0.003
V18.5 Passenger injured in traffic accident
0.003 0.997 0.000
E74.0 Glycogen storage disease
0.000 0.997 0.002
E84.8 Cystic fibrosis with other manifestations
0.001 0.997 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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