TreeWAS – Variant ID: rs9258740

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
E83.1 Disorders of iron metabolism	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
E00-E07 Disorders of thyroid gland	0.002	0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998
E70-E90 Metabolic disorders	0.004	0.996
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.996
E83 Disorders of mineral metabolism	0.004	0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.996
E16 Other disorders of pancreatic internal secretion	0.006	0.994
E16.2 Hypoglycaemia, unspecified	0.007	0.993
E03 Other hypothyroidism	0.007	0.993
E03.9 Hypothyroidism, unspecified	0.009	0.991
E05.9 Thyrotoxicosis, unspecified	0.020	0.980
E05.0 Thyrotoxicosis with diffuse goitre	0.021	0.979
M06 Other rheumatoid arthritis	0.034	0.966
E10-E14 Diabetes mellitus	0.038	0.962
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.039	0.961
M05-M14 Inflammatory polyarthropathies	0.064	0.936
M05 Seropositive rheumatoid arthritis	0.070	0.930
M05.9 Seropositive rheumatoid arthritis, unspecified	0.073	0.927
E10 Insulin-dependent diabetes mellitus	0.088	0.912
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.093	0.907
E89.0 Postprocedural hypothyroidism	0.093	0.907
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.103	0.897
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.121	0.879
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.124	0.876
E85 Amyloidosis	0.138	0.862
E89.2 Postprocedural hypoparathyroidism	0.149	0.851
E10.4 With neurological complications	0.162	0.837
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.163	0.837
E10.1 With ketoacidosis	0.173	0.827
M07 Psoriatic and enteropathic arthropathies	0.180	0.820
E80 Disorders of porphyrin and bilirubin metabolism	0.200	0.800
E11 Non-insulin-dependent diabetes mellitus	0.207	0.793
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.212	0.788
E11.3 With ophthalmic complications	0.215	0.785
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.221	0.779
E14 Unspecified diabetes mellitus	0.228	0.772
M11 Other crystal arthropathies	0.242	0.758
E74 Other disorders of carbohydrate metabolism	0.250	0.750
E10.6 With other specified complications	0.251	0.749
E03.8 Other specified hypothyroidism	0.253	0.747
M06.3 Rheumatoid nodule	0.253	0.747
E85.9 Amyloidosis, unspecified	0.257	0.743
M07.3 Other psoriatic arthropathies	0.262	0.738
E14.3 With ophthalmic complications	0.263	0.737
E10.0 With coma	0.276	0.724
E83.3 Disorders of phosphorus metabolism	0.282	0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.284	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.284	0.716
E79 Disorders of purine and pyrimidine metabolism	0.286	0.714
E77 Disorders of glycoprotein metabolism	0.286	0.714
E76 Disorders of glycosaminoglycan metabolism	0.286	0.714
E72 Other disorders of amino-acid metabolism	0.286	0.714
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.286	0.714
E70 Disorders of aromatic amino-acid metabolism	0.286	0.714
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.286	0.714
E05.5 Thyroid crisis or storm	0.286	0.714
E05.4 Thyrotoxicosis factitia	0.286	0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.286	0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.286	0.714
E83.9 Disorder of mineral metabolism, unspecified	0.286	0.714
E83.8 Other disorders of mineral metabolism	0.286	0.714
E83.2 Disorders of zinc metabolism	0.286	0.714
E83.0 Disorders of copper metabolism	0.286	0.714
E15 Nondiabetic hypoglycaemic coma	0.286	0.714
E16.0 Drug-induced hypoglycaemia without coma	0.287	0.713
E16.9 Disorder of pancreatic internal secretion, unspecified	0.287	0.712
E16.8 Other specified disorders of pancreatic internal secretion	0.287	0.712
E16.4 Abnormal secretion of gastrin	0.287	0.712
E16.3 Increased secretion of glucagon	0.287	0.712
E03.5 Myxoedema coma	0.288	0.712
E03.4 Atrophy of thyroid (acquired)	0.288	0.712
E03.3 Postinfectious hypothyroidism	0.288	0.712
E03.0 Congenital hypothyroidism with diffuse goitre	0.288	0.712
E73 Lactose intolerance	0.299	0.701
E05.8 Other thyrotoxicosis	0.302	0.698
E84 Cystic fibrosis	0.303	0.697
M06.8 Other specified rheumatoid arthritis	0.308	0.692
M06.2 Rheumatoid bursitis	0.308	0.692
M06.1 Adult-onset Still's disease	0.308	0.692
E10.5 With peripheral circulatory complications	0.310	0.690
E12 Malnutrition-related diabetes mellitus	0.310	0.690
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.311	0.689
E89.8 Other postprocedural endocrine and metabolic disorders	0.311	0.689
E89.5 Postprocedural testicular hypofunction	0.311	0.689
E89.4 Postprocedural ovarian failure	0.311	0.689
E89.1 Postprocedural hypoinsulinaemia	0.311	0.689
M06.0 Seronegative rheumatoid arthritis	0.311	0.689
M06.4 Inflammatory polyarthropathy	0.312	0.688
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.312	0.687
M07.39 Other psoriatic arthropathies (Site unspecified)	0.313	0.687
M10 Gout	0.324	0.676
E80.4 Gilbert's syndrome	0.327	0.673
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.329	0.671
M09 Juvenile arthritis in diseases classified elsewhere	0.329	0.671
M08 Juvenile arthritis	0.329	0.671
M05.8 Other seropositive rheumatoid arthritis	0.333	0.667
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.333	0.667
M05.2 Rheumatoid vasculitis	0.333	0.667
M05.1 Rheumatoid lung disease	0.333	0.667
M05.0 Felty's syndrome	0.333	0.667
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.335	0.664
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.335	0.664
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.335	0.664
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.335	0.664
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.335	0.664
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.335	0.664
E85.4 Organ-limited amyloidosis	0.336	0.664
E11.1 With ketoacidosis	0.340	0.660
E89.3 Postprocedural hypopituitarism	0.341	0.659
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.343	0.657
M14 Arthropathies in other diseases classified elsewhere	0.344	0.656
E10.7 With multiple complications	0.346	0.654
E50-E64 Other nutritional deficiencies	0.347	0.652
E10.2 With renal complications	0.356	0.644
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.359	0.641
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.360	0.640
E13 Other specified diabetes mellitus	0.366	0.634
E40-E46 Malnutrition	0.368	0.632
M11.2 Other chondrocalcinosis	0.370	0.630
E10.8 With unspecified complications	0.376	0.624
E16.1 Other hypoglycaemia	0.376	0.624
E85.8 Other amyloidosis	0.382	0.618
E85.3 Secondary systemic amyloidosis	0.382	0.618
E85.2 Heredofamilial amyloidosis, unspecified	0.382	0.618
E85.1 Neuropathic heredofamilial amyloidosis	0.382	0.618
E85.0 Nonneuropathic heredofamilial amyloidosis	0.382	0.618
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.387	0.613
M12 Other specific arthropathies	0.395	0.605
E65-E68 Obesity and other hyperalimentation	0.399	0.601
E03.1 Congenital hypothyroidism without goitre	0.401	0.599
M06.34 Rheumatoid nodule (Hand)	0.403	0.597
M07.6 Other enteropathic arthropathies	0.412	0.588
M07.5 Arthropathy in ulcerative colitis	0.412	0.588
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.412	0.588
M07.2 Psoriatic spondylitis	0.412	0.588
M07.1 Arthritis mutilans	0.412	0.588
M07.0 Distal interphalangeal psoriatic arthropathy	0.412	0.588
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.421	0.579
E80.6 Other disorders of bilirubin metabolism	0.424	0.576
E10.3 With ophthalmic complications	0.425	0.574
E74.3 Other disorders of intestinal carbohydrate absorption	0.426	0.574
E80.7 Disorder of bilirubin metabolism, unspecified	0.426	0.573
E80.5 Crigler-Najjar syndrome	0.426	0.573
E80.3 Defects of catalase and peroxydase	0.426	0.573
E80.1 Porphyria cutanea tarda	0.426	0.573
E80.0 Hereditary erythropoietic porphyria	0.426	0.573
E14.1 With ketoacidosis	0.429	0.571
E11.7 With multiple complications	0.431	0.569
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.432	0.568
E06 Thyroiditis	0.434	0.566
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.438	0.562
E53 Deficiency of other B group vitamins	0.438	0.561
M06.98 Rheumatoid arthritis, unspecified (Other)	0.444	0.555
E14.7 With multiple complications	0.446	0.554
E14.6 With other specified complications	0.446	0.554
E14.0 With coma	0.446	0.554
E14.5 With peripheral circulatory complications	0.449	0.551
E11.0 With coma	0.451	0.549
E07 Other disorders of thyroid	0.453	0.547
E14.4 With neurological complications	0.454	0.546
E80.2 Other porphyria	0.454	0.545
M11.9 Crystal arthropathy, unspecified	0.457	0.543
M11.8 Other specified crystal arthropathies	0.457	0.543
M11.1 Familial chondrocalcinosis	0.457	0.543
M11.0 Hydroxyapatite deposition disease	0.457	0.543
M07.34 Other psoriatic arthropathies (Hand)	0.461	0.539
M11.26 Other chondrocalcinosis (Lower leg)	0.461	0.539
E74.9 Disorder of carbohydrate metabolism, unspecified	0.462	0.538
E74.8 Other specified disorders of carbohydrate metabolism	0.462	0.538
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.462	0.538
E74.2 Disorders of galactose metabolism	0.462	0.538
E74.1 Disorders of fructose metabolism	0.462	0.538
E74.0 Glycogen storage disease	0.462	0.538
M06.39 Rheumatoid nodule (Site unspecified)	0.465	0.535
M06.38 Rheumatoid nodule (Other)	0.465	0.535
M06.36 Rheumatoid nodule (Lower leg)	0.465	0.535
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.465	0.535
M06.33 Rheumatoid nodule (Forearm)	0.465	0.535
M06.31 Rheumatoid nodule (Shoulder region)	0.465	0.535
M06.30 Rheumatoid nodule (Multiple sites)	0.465	0.535
E14.8 With unspecified complications	0.465	0.535
E14.2 Withrenal complications	0.465	0.534
M06.32 Rheumatoid nodule (Upper arm)	0.469	0.531
E11.5 With peripheral circulatory complications	0.470	0.530
M06.37 Rheumatoid nodule (Ankle and foot)	0.470	0.529
M07.38 Other psoriatic arthropathies (Other)	0.471	0.529
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.471	0.529
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.471	0.529
M07.33 Other psoriatic arthropathies (Forearm)	0.471	0.529
M07.32 Other psoriatic arthropathies (Upper arm)	0.471	0.529
M07.31 Other psoriatic arthropathies (Shoulder region)	0.471	0.529
E11.4 With neurological complications	0.473	0.527
E11.8 With unspecified complications	0.473	0.527
M07.36 Other psoriatic arthropathies (Lower leg)	0.485	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.487	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.487	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.487	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.487	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.487	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.487	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.487	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.487	0.513
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.488	0.512
E70.8 Other disorders of aromatic amino-acid metabolism	0.488	0.512
E70.3 Albinism	0.488	0.512
E70.2 Disorders of tyrosine metabolism	0.488	0.512
E70.1 Other hyperphenylalaninaemias	0.488	0.512
E70.0 Classical phenylketonuria	0.488	0.512
E71.3 Disorders of fatty-acid metabolism	0.488	0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.488	0.512
E71.1 Other disorders of branched-chain amino-acid metabolism	0.488	0.512
E71.0 Maple-syrup-urine disease	0.488	0.512
E72.9 Disorder of amino-acid metabolism, unspecified	0.488	0.512
E72.8 Other specified disorders of amino-acid metabolism	0.488	0.512
E72.5 Disorders of glycine metabolism	0.488	0.512
E72.4 Disorders of ornithine metabolism	0.488	0.512
E72.3 Disorders of lysine and hydroxylysine metabolism	0.488	0.512
E72.2 Disorders of urea cycle metabolism	0.488	0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.488	0.512
E72.0 Disorders of amino-acid transport	0.488	0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.488	0.512
E76.8 Other disorders of glucosaminoglycan metabolism	0.488	0.512
E76.3 Mucopolysaccharidosis, unspecified	0.488	0.512
E76.2 Other mucopolysaccharidoses	0.488	0.512
E76.1 Mucopolysaccharidosis, type II	0.488	0.512
E76.0 Mucopolysaccharidosis, type I	0.488	0.512
E77.9 Disorder of glycoprotein metabolism, unspecified	0.488	0.512
E77.8 Other disorders of glycoprotein metabolism	0.488	0.512
E77.1 Defects in glycoprotein degradation	0.488	0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.488	0.512
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.488	0.512
E79.8 Other disorders of purine and pyrimidine metabolism	0.488	0.512
E79.1 Lesch-Nyhan syndrome	0.488	0.512
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.488	0.512
E73.8 Other lactose intolerance	0.498	0.502
E73.1 Secondary lactase deficiency	0.498	0.502
E73.0 Congenital lactase deficiency	0.498	0.502
E84.8 Cystic fibrosis with other manifestations	0.500	0.500
E84.1 Cystic fibrosis with intestinal manifestations	0.500	0.500
E84.0 Cystic fibrosis with pulmonary manifestations	0.500	0.500
M07.30 Other psoriatic arthropathies (Multiple sites)	0.501	0.499
M06.19 Adult-onset Still's disease (Site unspecified)	0.503	0.496
M06.18 Adult-onset Still's disease (Other)	0.503	0.496
M06.17 Adult-onset Still's disease (Ankle and foot)	0.503	0.496
M06.16 Adult-onset Still's disease (Lower leg)	0.503	0.496
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.503	0.496
M06.14 Adult-onset Still's disease (Hand)	0.503	0.496
M06.13 Adult-onset Still's disease (Forearm)	0.503	0.496
M06.12 Adult-onset Still's disease (Upper arm)	0.503	0.496
M06.11 Adult-onset Still's disease (Shoulder region)	0.503	0.496
M06.10 Adult-onset Still's disease (Multiple sites)	0.503	0.496
M06.29 Rheumatoid bursitis (Site unspecified)	0.503	0.496
M06.28 Rheumatoid bursitis (Other)	0.503	0.496
M06.27 Rheumatoid bursitis (Ankle and foot)	0.503	0.496
M06.26 Rheumatoid bursitis (Lower leg)	0.503	0.496
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.503	0.496
M06.24 Rheumatoid bursitis (Hand)	0.503	0.496
M06.23 Rheumatoid bursitis (Forearm)	0.503	0.496
M06.22 Rheumatoid bursitis (Upper arm)	0.503	0.496
M06.21 Rheumatoid bursitis (Shoulder region)	0.503	0.496
M06.20 Rheumatoid bursitis (Multiple sites)	0.503	0.496
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.503	0.496
M06.88 Other specified rheumatoid arthritis (Other)	0.503	0.496
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.503	0.496
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.503	0.496
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.503	0.496
M06.84 Other specified rheumatoid arthritis (Hand)	0.503	0.496
M06.83 Other specified rheumatoid arthritis (Forearm)	0.503	0.496
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.503	0.496
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.503	0.496
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.503	0.496
E12.9 Without complications	0.505	0.495
E12.8 With unspecified complications	0.505	0.495
E12.7 With multiple complications	0.505	0.495
E12.6 With other specified complications	0.505	0.495
E12.5 With peripheral circulatory complications	0.505	0.495
E12.4 With neurological complications	0.505	0.495
E12.3 With ophthalmic complications	0.505	0.495
E12.2 With renal complications	0.505	0.495
E12.1 With ketoacidosis	0.505	0.495
E12.0 With coma	0.505	0.495
M06.08 Seronegative rheumatoid arthritis (Other)	0.506	0.494
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.506	0.494
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.506	0.494
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.506	0.494
M06.04 Seronegative rheumatoid arthritis (Hand)	0.506	0.494
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.506	0.494
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.506	0.494
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.506	0.494
M06.48 Inflammatory polyarthropathy (Other)	0.506	0.493
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.506	0.493
M06.46 Inflammatory polyarthropathy (Lower leg)	0.506	0.493
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.506	0.493
M06.44 Inflammatory polyarthropathy (Hand)	0.506	0.493
M06.43 Inflammatory polyarthropathy (Forearm)	0.506	0.493
M06.42 Inflammatory polyarthropathy (Upper arm)	0.506	0.493
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.506	0.493
M10.9 Gout, unspecified	0.511	0.489
E73.9 Lactose intolerance, unspecified	0.511	0.489
E65 Localised adiposity	0.512	0.488
M10.4 Other secondary gout	0.515	0.484
M10.3 Gout due to impairment of renal function	0.515	0.484
M10.2 Drug-induced gout	0.515	0.484
M10.1 Lead-induced gout	0.515	0.484
M10.0 Idiopathic gout	0.515	0.484
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.517	0.483
E84.9 Cystic fibrosis, unspecified	0.518	0.482
E75.6 Lipid storage disorder, unspecified	0.518	0.481
E75.4 Neuronal ceroid lipofuscinosis	0.518	0.481
E75.3 Sphingolipidosis, unspecified	0.518	0.481
E75.2 Other sphingolipidosis	0.518	0.481
E75.1 Other gangliosidosis	0.518	0.481
E75.0 GM2 gangliosidosis	0.518	0.481
M08.9 Juvenile arthritis, unspecified	0.519	0.481
M08.8 Other juvenile arthritis	0.519	0.481
M08.4 Pauciarticular juvenile arthritis	0.519	0.481
M08.3 Juvenile polyarthritis (seronegative)	0.519	0.481
M08.2 Juvenile arthritis with systemic onset	0.519	0.481
M08.1 Juvenile ankylosing spondylitis	0.519	0.481
M08.0 Juvenile rheumatoid arthritis	0.519	0.481
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.519	0.481
M09.2 Juvenile arthritis in ulcerative colitis	0.519	0.481
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.519	0.481
M09.0 Juvenile arthritis in psoriasis	0.519	0.481
E53.8 Deficiency of other specified B group vitamins	0.521	0.479
M05.09 Felty's syndrome (Site unspecified)	0.522	0.478
M05.08 Felty's syndrome (Other)	0.522	0.478
M05.07 Felty's syndrome (Ankle and foot)	0.522	0.478
M05.06 Felty's syndrome (Lower leg)	0.522	0.478
M05.05 Felty's syndrome (Pelvic region and thigh)	0.522	0.478
M05.04 Felty's syndrome (Hand)	0.522	0.478
M05.03 Felty's syndrome (Forearm)	0.522	0.478
M05.02 Felty's syndrome (Upper arm)	0.522	0.478
M05.01 Felty's syndrome (Shoulder region)	0.522	0.478
M05.00 Felty's syndrome (Multiple sites)	0.522	0.478
M05.19 Rheumatoid lung disease (Site unspecified)	0.522	0.478
M05.18 Rheumatoid lung disease (Other)	0.522	0.478
M05.17 Rheumatoid lung disease (Ankle and foot)	0.522	0.478
M05.16 Rheumatoid lung disease (Lower leg)	0.522	0.478
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.522	0.478
M05.14 Rheumatoid lung disease (Hand)	0.522	0.478
M05.13 Rheumatoid lung disease (Forearm)	0.522	0.478
M05.12 Rheumatoid lung disease (Upper arm)	0.522	0.478
M05.11 Rheumatoid lung disease (Shoulder region)	0.522	0.478
M05.10 Rheumatoid lung disease (Multiple sites)	0.522	0.478
M05.29 Rheumatoid vasculitis (Site unspecified)	0.522	0.478
M05.28 Rheumatoid vasculitis (Other)	0.522	0.478
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.522	0.478
M05.26 Rheumatoid vasculitis (Lower leg)	0.522	0.478
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.522	0.478
M05.24 Rheumatoid vasculitis (Hand)	0.522	0.478
M05.23 Rheumatoid vasculitis (Forearm)	0.522	0.478
M05.22 Rheumatoid vasculitis (Upper arm)	0.522	0.478
M05.21 Rheumatoid vasculitis (Shoulder region)	0.522	0.478
M05.20 Rheumatoid vasculitis (Multiple sites)	0.522	0.478
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.522	0.478
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.522	0.478
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.522	0.478
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.522	0.478
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.522	0.478
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.522	0.478
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.522	0.478
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.522	0.478
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.522	0.478
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.522	0.478
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.522	0.478
M05.88 Other seropositive rheumatoid arthritis (Other)	0.522	0.478
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.522	0.478
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.522	0.478
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.522	0.478
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.522	0.478
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.522	0.478
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.522	0.478
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.522	0.478
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.522	0.478
E83.4 Disorders of magnesium metabolism	0.526	0.474
M14.8 Arthropathies in other specified diseases classified elsewhere	0.530	0.470
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.530	0.470
M14.4 Arthropathy in amyloidosis	0.530	0.470
M14.3 Lipoid dermatoarthritis	0.530	0.470
M14.2 Diabetic arthropathy	0.530	0.470
M14.1 Crystal arthropathy in other metabolic disorders	0.530	0.470
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.530	0.470
E64 Sequelae of malnutrition and other nutritional deficiencies	0.532	0.468
E63 Other nutritional deficiencies	0.532	0.468
E56 Other vitamin deficiencies	0.532	0.468
E51 Thiamine deficiency	0.532	0.468
E50 Vitamin A deficiency	0.532	0.468
E60 Dietary zinc deficiency	0.532	0.468
E59 Dietary selenium deficiency	0.532	0.468
E58 Dietary calcium deficiency	0.532	0.468
E54 Ascorbic acid deficiency	0.532	0.468
E52 Niacin deficiency [pellagra]	0.532	0.468
E88 Other metabolic disorders	0.542	0.457
M14.6 Neuropathic arthropathy	0.545	0.455
E13.8 With unspecified complications	0.545	0.455
E13.7 With multiple complications	0.545	0.455
E13.6 With other specified complications	0.545	0.455
E13.5 With peripheral circulatory complications	0.545	0.455
E13.4 With neurological complications	0.545	0.455
E13.3 With ophthalmic complications	0.545	0.455
E13.2 With renal complications	0.545	0.455
E13.1 With ketoacidosis	0.545	0.455
E13.0 With coma	0.545	0.455
E44 Protein-energy malnutrition of moderate and mild degree	0.547	0.453
E45 Retarded development following protein-energy malnutrition	0.547	0.453
E43 Unspecified severe protein-energy malnutrition	0.547	0.453
E42 Marasmic kwashiorkor	0.547	0.453
E41 Nutritional marasmus	0.547	0.453
E40 Kwashiorkor	0.547	0.453
M11.29 Other chondrocalcinosis (Site unspecified)	0.548	0.452
M11.28 Other chondrocalcinosis (Other)	0.548	0.452
M11.27 Other chondrocalcinosis (Ankle and foot)	0.548	0.452
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.548	0.452
M11.24 Other chondrocalcinosis (Hand)	0.548	0.452
M11.23 Other chondrocalcinosis (Forearm)	0.548	0.452
M11.22 Other chondrocalcinosis (Upper arm)	0.548	0.452
M11.21 Other chondrocalcinosis (Shoulder region)	0.548	0.452
M11.20 Other chondrocalcinosis (Multiple sites)	0.548	0.452
M10.97 Gout, unspecified (Ankle and foot)	0.558	0.442
E75.5 Other lipid storage disorders	0.561	0.438
E53.9 Vitamin B deficiency, unspecified	0.564	0.435
M12.8 Other specific arthropathies, not elsewhere classified	0.566	0.434
M12.5 Traumatic arthropathy	0.566	0.434
M12.4 Intermittent hydrarthrosis	0.566	0.434
M12.2 Villonodular synovitis (pigmented)	0.566	0.434
M12.1 Kaschin-Beck disease	0.566	0.434
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.566	0.434
E67 Other hyperalimentation	0.569	0.431
E68 Sequelae of hyperalimentation	0.569	0.431
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.578	0.422
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.578	0.422
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.578	0.422
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.578	0.422
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.578	0.422
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.578	0.422
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.578	0.422
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.578	0.422
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.578	0.422
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.578	0.422
M07.19 Arthritis mutilans (Site unspecified)	0.578	0.422
M07.18 Arthritis mutilans (Other)	0.578	0.422
M07.17 Arthritis mutilans (Ankle and foot)	0.578	0.422
M07.16 Arthritis mutilans (Lower leg)	0.578	0.422
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.578	0.422
M07.14 Arthritis mutilans (Hand)	0.578	0.422
M07.13 Arthritis mutilans (Forearm)	0.578	0.422
M07.12 Arthritis mutilans (Upper arm)	0.578	0.422
M07.11 Arthritis mutilans (Shoulder region)	0.578	0.422
M07.10 Arthritis mutilans (Multiple sites)	0.578	0.422
M07.29 Psoriatic spondylitis (Site unspecified)	0.578	0.422
M07.28 Psoriatic spondylitis (Other)	0.578	0.422
M07.27 Psoriatic spondylitis (Ankle and foot)	0.578	0.422
M07.26 Psoriatic spondylitis (Lower leg)	0.578	0.422
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.578	0.422
M07.24 Psoriatic spondylitis (Hand)	0.578	0.422
M07.23 Psoriatic spondylitis (Forearm)	0.578	0.422
M07.22 Psoriatic spondylitis (Upper arm)	0.578	0.422
M07.21 Psoriatic spondylitis (Shoulder region)	0.578	0.422
M07.20 Psoriatic spondylitis (Multiple sites)	0.578	0.422
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.578	0.422
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.578	0.422
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.578	0.422
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.578	0.422
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.578	0.422
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.578	0.422
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.578	0.422
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.578	0.422
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.578	0.422
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.578	0.422
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.578	0.422
M07.58 Arthropathy in ulcerative colitis (Other)	0.578	0.422
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.578	0.422
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.578	0.422
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.578	0.422
M07.54 Arthropathy in ulcerative colitis (Hand)	0.578	0.422
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.578	0.422
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.578	0.422
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.578	0.422
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.578	0.422
M07.69 Other enteropathic arthropathies (Site unspecified)	0.578	0.422
M07.68 Other enteropathic arthropathies (Other)	0.578	0.422
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.578	0.422
M07.66 Other enteropathic arthropathies (Lower leg)	0.578	0.422
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.578	0.422
M07.64 Other enteropathic arthropathies (Hand)	0.578	0.422
M07.63 Other enteropathic arthropathies (Forearm)	0.578	0.422
M07.62 Other enteropathic arthropathies (Upper arm)	0.578	0.422
M07.61 Other enteropathic arthropathies (Shoulder region)	0.578	0.422
M07.60 Other enteropathic arthropathies (Multiple sites)	0.578	0.422
E06.5 Other chronic thyroiditis	0.594	0.406
E06.4 Drug-induced thyroiditis	0.594	0.406
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.594	0.406
E06.1 Subacute thyroiditis	0.594	0.406

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations