TreeWAS – Variant ID: rs9258750

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E00-E07 Disorders of thyroid gland	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.001	0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998
E70-E90 Metabolic disorders	0.002	0.998
E83 Disorders of mineral metabolism	0.002	0.998
E16 Other disorders of pancreatic internal secretion	0.003	0.997
E16.2 Hypoglycaemia, unspecified	0.003	0.997
E03 Other hypothyroidism	0.007	0.993
E03.9 Hypothyroidism, unspecified	0.009	0.991
E05.0 Thyrotoxicosis with diffuse goitre	0.014	0.986
E05.9 Thyrotoxicosis, unspecified	0.017	0.983
E10-E14 Diabetes mellitus	0.026	0.974
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.034	0.966
M06 Other rheumatoid arthritis	0.039	0.961
E10 Insulin-dependent diabetes mellitus	0.060	0.940
M05-M14 Inflammatory polyarthropathies	0.068	0.932
M05 Seropositive rheumatoid arthritis	0.074	0.926
M05.9 Seropositive rheumatoid arthritis, unspecified	0.077	0.923
E89.0 Postprocedural hypothyroidism	0.083	0.917
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.097	0.903
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.107	0.893
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.121	0.879
E10.4 With neurological complications	0.126	0.874
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.130	0.870
E85 Amyloidosis	0.137	0.863
E10.1 With ketoacidosis	0.139	0.861
E89.2 Postprocedural hypoparathyroidism	0.144	0.856
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.163	0.837
M07 Psoriatic and enteropathic arthropathies	0.188	0.812
E11 Non-insulin-dependent diabetes mellitus	0.200	0.800
E11.3 With ophthalmic complications	0.208	0.792
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.212	0.788
E14 Unspecified diabetes mellitus	0.214	0.786
E80 Disorders of porphyrin and bilirubin metabolism	0.216	0.784
E10.6 With other specified complications	0.228	0.772
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.229	0.771
E74 Other disorders of carbohydrate metabolism	0.242	0.758
M11 Other crystal arthropathies	0.245	0.755
E14.3 With ophthalmic complications	0.250	0.750
E03.8 Other specified hypothyroidism	0.252	0.748
E10.0 With coma	0.253	0.747
E85.9 Amyloidosis, unspecified	0.255	0.745
M06.3 Rheumatoid nodule	0.256	0.744
M07.3 Other psoriatic arthropathies	0.273	0.727
E83.3 Disorders of phosphorus metabolism	0.280	0.720
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.284	0.716
E16.0 Drug-induced hypoglycaemia without coma	0.284	0.716
E05.5 Thyroid crisis or storm	0.285	0.715
E05.4 Thyrotoxicosis factitia	0.285	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.285	0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.285	0.715
E79 Disorders of purine and pyrimidine metabolism	0.285	0.715
E77 Disorders of glycoprotein metabolism	0.285	0.715
E76 Disorders of glycosaminoglycan metabolism	0.285	0.715
E72 Other disorders of amino-acid metabolism	0.285	0.715
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.285	0.715
E70 Disorders of aromatic amino-acid metabolism	0.285	0.715
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.285	0.715
E83.9 Disorder of mineral metabolism, unspecified	0.285	0.715
E83.8 Other disorders of mineral metabolism	0.285	0.715
E83.2 Disorders of zinc metabolism	0.285	0.715
E83.0 Disorders of copper metabolism	0.285	0.715
E16.9 Disorder of pancreatic internal secretion, unspecified	0.285	0.715
E16.8 Other specified disorders of pancreatic internal secretion	0.285	0.715
E16.4 Abnormal secretion of gastrin	0.285	0.715
E16.3 Increased secretion of glucagon	0.285	0.715
E03.5 Myxoedema coma	0.288	0.712
E03.4 Atrophy of thyroid (acquired)	0.288	0.712
E03.3 Postinfectious hypothyroidism	0.288	0.712
E03.0 Congenital hypothyroidism with diffuse goitre	0.288	0.712
E10.5 With peripheral circulatory complications	0.288	0.712
E73 Lactose intolerance	0.298	0.702
E50-E64 Other nutritional deficiencies	0.300	0.700
E05.8 Other thyrotoxicosis	0.300	0.699
E12 Malnutrition-related diabetes mellitus	0.301	0.699
E84 Cystic fibrosis	0.302	0.698
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.307	0.693
E89.8 Other postprocedural endocrine and metabolic disorders	0.307	0.693
E89.5 Postprocedural testicular hypofunction	0.307	0.693
E89.4 Postprocedural ovarian failure	0.307	0.693
E89.1 Postprocedural hypoinsulinaemia	0.307	0.693
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.309	0.691
M06.8 Other specified rheumatoid arthritis	0.311	0.689
M06.2 Rheumatoid bursitis	0.311	0.689
M06.1 Adult-onset Still's disease	0.311	0.689
M06.4 Inflammatory polyarthropathy	0.315	0.685
M10 Gout	0.320	0.680
M07.39 Other psoriatic arthropathies (Site unspecified)	0.323	0.677
E10.7 With multiple complications	0.326	0.674
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.327	0.672
M09 Juvenile arthritis in diseases classified elsewhere	0.332	0.668
M08 Juvenile arthritis	0.332	0.668
E11.1 With ketoacidosis	0.334	0.666
E85.4 Organ-limited amyloidosis	0.335	0.665
M05.8 Other seropositive rheumatoid arthritis	0.336	0.664
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.336	0.664
M05.2 Rheumatoid vasculitis	0.336	0.664
M05.1 Rheumatoid lung disease	0.336	0.664
M05.0 Felty's syndrome	0.336	0.664
E10.2 With renal complications	0.336	0.664
E89.3 Postprocedural hypopituitarism	0.337	0.663
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.338	0.662
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.338	0.662
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.338	0.662
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.338	0.662
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.338	0.662
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.338	0.662
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.343	0.657
M14 Arthropathies in other diseases classified elsewhere	0.347	0.653
M06.0 Seronegative rheumatoid arthritis	0.353	0.647
E80.4 Gilbert's syndrome	0.354	0.646
E10.8 With unspecified complications	0.357	0.643
E13 Other specified diabetes mellitus	0.357	0.643
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.363	0.637
E40-E46 Malnutrition	0.367	0.633
M11.2 Other chondrocalcinosis	0.371	0.629
E16.1 Other hypoglycaemia	0.374	0.626
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.377	0.623
E53 Deficiency of other B group vitamins	0.379	0.621
E10.3 With ophthalmic complications	0.381	0.619
E85.8 Other amyloidosis	0.381	0.619
E85.3 Secondary systemic amyloidosis	0.381	0.619
E85.2 Heredofamilial amyloidosis, unspecified	0.381	0.619
E85.1 Neuropathic heredofamilial amyloidosis	0.381	0.619
E85.0 Nonneuropathic heredofamilial amyloidosis	0.381	0.619
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.389	0.610
M12 Other specific arthropathies	0.397	0.603
E65-E68 Obesity and other hyperalimentation	0.400	0.600
E03.1 Congenital hypothyroidism without goitre	0.400	0.600
M06.34 Rheumatoid nodule (Hand)	0.405	0.595
E74.3 Other disorders of intestinal carbohydrate absorption	0.413	0.587
M07.6 Other enteropathic arthropathies	0.418	0.582
M07.5 Arthropathy in ulcerative colitis	0.418	0.582
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.418	0.582
M07.2 Psoriatic spondylitis	0.418	0.582
M07.1 Arthritis mutilans	0.418	0.582
M07.0 Distal interphalangeal psoriatic arthropathy	0.418	0.582
E14.1 With ketoacidosis	0.419	0.581
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.420	0.580
E11.7 With multiple complications	0.426	0.574
E06 Thyroiditis	0.432	0.567
E80.6 Other disorders of bilirubin metabolism	0.435	0.565
E14.7 With multiple complications	0.437	0.563
E14.6 With other specified complications	0.437	0.563
E14.0 With coma	0.437	0.563
E80.7 Disorder of bilirubin metabolism, unspecified	0.438	0.562
E80.5 Crigler-Najjar syndrome	0.438	0.562
E80.3 Defects of catalase and peroxydase	0.438	0.562
E80.1 Porphyria cutanea tarda	0.438	0.562
E80.0 Hereditary erythropoietic porphyria	0.438	0.562
E14.5 With peripheral circulatory complications	0.440	0.560
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.440	0.560
M06.98 Rheumatoid arthritis, unspecified (Other)	0.444	0.555
E14.4 With neurological complications	0.445	0.555
E11.0 With coma	0.446	0.554
E07 Other disorders of thyroid	0.447	0.553
E53.8 Deficiency of other specified B group vitamins	0.450	0.550
E14.8 With unspecified complications	0.456	0.544
E74.9 Disorder of carbohydrate metabolism, unspecified	0.456	0.544
E74.8 Other specified disorders of carbohydrate metabolism	0.456	0.544
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.456	0.544
E74.2 Disorders of galactose metabolism	0.456	0.544
E74.1 Disorders of fructose metabolism	0.456	0.544
E74.0 Glycogen storage disease	0.456	0.544
E14.2 Withrenal complications	0.456	0.544
M11.9 Crystal arthropathy, unspecified	0.458	0.542
M11.8 Other specified crystal arthropathies	0.458	0.542
M11.1 Familial chondrocalcinosis	0.458	0.542
M11.0 Hydroxyapatite deposition disease	0.458	0.542
M11.26 Other chondrocalcinosis (Lower leg)	0.461	0.539
E11.5 With peripheral circulatory complications	0.463	0.537
E80.2 Other porphyria	0.465	0.535
M06.39 Rheumatoid nodule (Site unspecified)	0.467	0.533
M06.38 Rheumatoid nodule (Other)	0.467	0.533
M06.36 Rheumatoid nodule (Lower leg)	0.467	0.533
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.467	0.533
M06.33 Rheumatoid nodule (Forearm)	0.467	0.533
M06.31 Rheumatoid nodule (Shoulder region)	0.467	0.533
M06.30 Rheumatoid nodule (Multiple sites)	0.467	0.533
E11.8 With unspecified complications	0.468	0.532
M06.32 Rheumatoid nodule (Upper arm)	0.471	0.529
M06.37 Rheumatoid nodule (Ankle and foot)	0.472	0.527
E11.4 With neurological complications	0.473	0.527
M07.34 Other psoriatic arthropathies (Hand)	0.476	0.524
E83.4 Disorders of magnesium metabolism	0.478	0.521
M07.38 Other psoriatic arthropathies (Other)	0.479	0.521
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.479	0.521
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.479	0.521
M07.33 Other psoriatic arthropathies (Forearm)	0.479	0.521
M07.32 Other psoriatic arthropathies (Upper arm)	0.479	0.521
M07.31 Other psoriatic arthropathies (Shoulder region)	0.479	0.521
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.486	0.514
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.487	0.513
E70.8 Other disorders of aromatic amino-acid metabolism	0.487	0.513
E70.3 Albinism	0.487	0.513
E70.2 Disorders of tyrosine metabolism	0.487	0.513
E70.1 Other hyperphenylalaninaemias	0.487	0.513
E70.0 Classical phenylketonuria	0.487	0.513
E71.3 Disorders of fatty-acid metabolism	0.487	0.513
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.487	0.513
E71.1 Other disorders of branched-chain amino-acid metabolism	0.487	0.513
E71.0 Maple-syrup-urine disease	0.487	0.513
E72.9 Disorder of amino-acid metabolism, unspecified	0.487	0.513
E72.8 Other specified disorders of amino-acid metabolism	0.487	0.513
E72.5 Disorders of glycine metabolism	0.487	0.513
E72.4 Disorders of ornithine metabolism	0.487	0.513
E72.3 Disorders of lysine and hydroxylysine metabolism	0.487	0.513
E72.2 Disorders of urea cycle metabolism	0.487	0.513
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.487	0.513
E72.0 Disorders of amino-acid transport	0.487	0.513
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.487	0.513
E76.8 Other disorders of glucosaminoglycan metabolism	0.487	0.513
E76.3 Mucopolysaccharidosis, unspecified	0.487	0.513
E76.2 Other mucopolysaccharidoses	0.487	0.513
E76.1 Mucopolysaccharidosis, type II	0.487	0.513
E76.0 Mucopolysaccharidosis, type I	0.487	0.513
E77.9 Disorder of glycoprotein metabolism, unspecified	0.487	0.513
E77.8 Other disorders of glycoprotein metabolism	0.487	0.513
E77.1 Defects in glycoprotein degradation	0.487	0.513
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.487	0.513
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.487	0.513
E79.8 Other disorders of purine and pyrimidine metabolism	0.487	0.513
E79.1 Lesch-Nyhan syndrome	0.487	0.513
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.487	0.513
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.490	0.510
M07.36 Other psoriatic arthropathies (Lower leg)	0.492	0.508
E73.8 Other lactose intolerance	0.496	0.503
E73.1 Secondary lactase deficiency	0.496	0.503
E73.0 Congenital lactase deficiency	0.496	0.503
E64 Sequelae of malnutrition and other nutritional deficiencies	0.498	0.502
E63 Other nutritional deficiencies	0.498	0.502
E56 Other vitamin deficiencies	0.498	0.502
E51 Thiamine deficiency	0.498	0.502
E50 Vitamin A deficiency	0.498	0.502
E60 Dietary zinc deficiency	0.498	0.502
E59 Dietary selenium deficiency	0.498	0.502
E58 Dietary calcium deficiency	0.498	0.502
E54 Ascorbic acid deficiency	0.498	0.502
E52 Niacin deficiency [pellagra]	0.498	0.502
E12.9 Without complications	0.499	0.501
E12.8 With unspecified complications	0.499	0.501
E12.7 With multiple complications	0.499	0.501
E12.6 With other specified complications	0.499	0.501
E12.5 With peripheral circulatory complications	0.499	0.501
E12.4 With neurological complications	0.499	0.501
E12.3 With ophthalmic complications	0.499	0.501
E12.2 With renal complications	0.499	0.501
E12.1 With ketoacidosis	0.499	0.501
E12.0 With coma	0.499	0.501
E84.8 Cystic fibrosis with other manifestations	0.499	0.500
E84.1 Cystic fibrosis with intestinal manifestations	0.499	0.500
E84.0 Cystic fibrosis with pulmonary manifestations	0.499	0.500
M10.9 Gout, unspecified	0.501	0.499
M06.19 Adult-onset Still's disease (Site unspecified)	0.506	0.494
M06.18 Adult-onset Still's disease (Other)	0.506	0.494
M06.17 Adult-onset Still's disease (Ankle and foot)	0.506	0.494
M06.16 Adult-onset Still's disease (Lower leg)	0.506	0.494
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.506	0.494
M06.14 Adult-onset Still's disease (Hand)	0.506	0.494
M06.13 Adult-onset Still's disease (Forearm)	0.506	0.494
M06.12 Adult-onset Still's disease (Upper arm)	0.506	0.494
M06.11 Adult-onset Still's disease (Shoulder region)	0.506	0.494
M06.10 Adult-onset Still's disease (Multiple sites)	0.506	0.494
M06.29 Rheumatoid bursitis (Site unspecified)	0.506	0.494
M06.28 Rheumatoid bursitis (Other)	0.506	0.494
M06.27 Rheumatoid bursitis (Ankle and foot)	0.506	0.494
M06.26 Rheumatoid bursitis (Lower leg)	0.506	0.494
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.506	0.494
M06.24 Rheumatoid bursitis (Hand)	0.506	0.494
M06.23 Rheumatoid bursitis (Forearm)	0.506	0.494
M06.22 Rheumatoid bursitis (Upper arm)	0.506	0.494
M06.21 Rheumatoid bursitis (Shoulder region)	0.506	0.494
M06.20 Rheumatoid bursitis (Multiple sites)	0.506	0.494
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.506	0.494
M06.88 Other specified rheumatoid arthritis (Other)	0.506	0.494
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.506	0.494
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.506	0.494
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.506	0.494
M06.84 Other specified rheumatoid arthritis (Hand)	0.506	0.494
M06.83 Other specified rheumatoid arthritis (Forearm)	0.506	0.494
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.506	0.494
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.506	0.494
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.506	0.494
M06.48 Inflammatory polyarthropathy (Other)	0.508	0.491
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.508	0.491
M06.46 Inflammatory polyarthropathy (Lower leg)	0.508	0.491
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.508	0.491
M06.44 Inflammatory polyarthropathy (Hand)	0.508	0.491
M06.43 Inflammatory polyarthropathy (Forearm)	0.508	0.491
M06.42 Inflammatory polyarthropathy (Upper arm)	0.508	0.491
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.508	0.491
E73.9 Lactose intolerance, unspecified	0.510	0.490
M10.4 Other secondary gout	0.512	0.487
M10.3 Gout due to impairment of renal function	0.512	0.487
M10.2 Drug-induced gout	0.512	0.487
M10.1 Lead-induced gout	0.512	0.487
M10.0 Idiopathic gout	0.512	0.487
E65 Localised adiposity	0.513	0.487
M07.30 Other psoriatic arthropathies (Multiple sites)	0.514	0.486
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.516	0.484
E84.9 Cystic fibrosis, unspecified	0.517	0.483
E75.6 Lipid storage disorder, unspecified	0.518	0.482
E75.4 Neuronal ceroid lipofuscinosis	0.518	0.482
E75.3 Sphingolipidosis, unspecified	0.518	0.482
E75.2 Other sphingolipidosis	0.518	0.482
E75.1 Other gangliosidosis	0.518	0.482
E75.0 GM2 gangliosidosis	0.518	0.482
E53.9 Vitamin B deficiency, unspecified	0.518	0.481
M08.9 Juvenile arthritis, unspecified	0.521	0.479
M08.8 Other juvenile arthritis	0.521	0.479
M08.4 Pauciarticular juvenile arthritis	0.521	0.479
M08.3 Juvenile polyarthritis (seronegative)	0.521	0.479
M08.2 Juvenile arthritis with systemic onset	0.521	0.479
M08.1 Juvenile ankylosing spondylitis	0.521	0.479
M08.0 Juvenile rheumatoid arthritis	0.521	0.479
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.521	0.479
M09.2 Juvenile arthritis in ulcerative colitis	0.521	0.479
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.521	0.479
M09.0 Juvenile arthritis in psoriasis	0.521	0.479
M05.09 Felty's syndrome (Site unspecified)	0.524	0.476
M05.08 Felty's syndrome (Other)	0.524	0.476
M05.07 Felty's syndrome (Ankle and foot)	0.524	0.476
M05.06 Felty's syndrome (Lower leg)	0.524	0.476
M05.05 Felty's syndrome (Pelvic region and thigh)	0.524	0.476
M05.04 Felty's syndrome (Hand)	0.524	0.476
M05.03 Felty's syndrome (Forearm)	0.524	0.476
M05.02 Felty's syndrome (Upper arm)	0.524	0.476
M05.01 Felty's syndrome (Shoulder region)	0.524	0.476
M05.00 Felty's syndrome (Multiple sites)	0.524	0.476
M05.19 Rheumatoid lung disease (Site unspecified)	0.524	0.476
M05.18 Rheumatoid lung disease (Other)	0.524	0.476
M05.17 Rheumatoid lung disease (Ankle and foot)	0.524	0.476
M05.16 Rheumatoid lung disease (Lower leg)	0.524	0.476
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.524	0.476
M05.14 Rheumatoid lung disease (Hand)	0.524	0.476
M05.13 Rheumatoid lung disease (Forearm)	0.524	0.476
M05.12 Rheumatoid lung disease (Upper arm)	0.524	0.476
M05.11 Rheumatoid lung disease (Shoulder region)	0.524	0.476
M05.10 Rheumatoid lung disease (Multiple sites)	0.524	0.476
M05.29 Rheumatoid vasculitis (Site unspecified)	0.524	0.476
M05.28 Rheumatoid vasculitis (Other)	0.524	0.476
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.524	0.476
M05.26 Rheumatoid vasculitis (Lower leg)	0.524	0.476
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.524	0.476
M05.24 Rheumatoid vasculitis (Hand)	0.524	0.476
M05.23 Rheumatoid vasculitis (Forearm)	0.524	0.476
M05.22 Rheumatoid vasculitis (Upper arm)	0.524	0.476
M05.21 Rheumatoid vasculitis (Shoulder region)	0.524	0.476
M05.20 Rheumatoid vasculitis (Multiple sites)	0.524	0.476
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.524	0.476
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.524	0.476
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.524	0.476
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.524	0.476
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.524	0.476
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.524	0.476
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.524	0.476
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.524	0.476
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.524	0.476
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.524	0.476
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.524	0.476
M05.88 Other seropositive rheumatoid arthritis (Other)	0.524	0.476
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.524	0.476
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.524	0.476
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.524	0.476
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.524	0.476
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.524	0.476
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.524	0.476
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.524	0.476
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.524	0.476
M14.8 Arthropathies in other specified diseases classified elsewhere	0.531	0.468
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.531	0.468
M14.4 Arthropathy in amyloidosis	0.531	0.468
M14.3 Lipoid dermatoarthritis	0.531	0.468
M14.2 Diabetic arthropathy	0.531	0.468
M14.1 Crystal arthropathy in other metabolic disorders	0.531	0.468
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.531	0.468
M06.08 Seronegative rheumatoid arthritis (Other)	0.536	0.464
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.536	0.464
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.536	0.464
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.536	0.464
M06.04 Seronegative rheumatoid arthritis (Hand)	0.536	0.464
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.536	0.464
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.536	0.464
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.536	0.464
E13.8 With unspecified complications	0.539	0.461
E13.7 With multiple complications	0.539	0.461
E13.6 With other specified complications	0.539	0.461
E13.5 With peripheral circulatory complications	0.539	0.461
E13.4 With neurological complications	0.539	0.461
E13.3 With ophthalmic complications	0.539	0.461
E13.2 With renal complications	0.539	0.461
E13.1 With ketoacidosis	0.539	0.461
E13.0 With coma	0.539	0.461
E88 Other metabolic disorders	0.540	0.459
E44 Protein-energy malnutrition of moderate and mild degree	0.546	0.454
E45 Retarded development following protein-energy malnutrition	0.546	0.454
E43 Unspecified severe protein-energy malnutrition	0.546	0.454
E42 Marasmic kwashiorkor	0.546	0.454
E41 Nutritional marasmus	0.546	0.454
E40 Kwashiorkor	0.546	0.454
M14.6 Neuropathic arthropathy	0.546	0.454
M10.97 Gout, unspecified (Ankle and foot)	0.548	0.452
M11.29 Other chondrocalcinosis (Site unspecified)	0.549	0.451
M11.28 Other chondrocalcinosis (Other)	0.549	0.451
M11.27 Other chondrocalcinosis (Ankle and foot)	0.549	0.451
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.549	0.451
M11.24 Other chondrocalcinosis (Hand)	0.549	0.451
M11.23 Other chondrocalcinosis (Forearm)	0.549	0.451
M11.22 Other chondrocalcinosis (Upper arm)	0.549	0.451
M11.21 Other chondrocalcinosis (Shoulder region)	0.549	0.451
M11.20 Other chondrocalcinosis (Multiple sites)	0.549	0.451
E53.1 Pyridoxine deficiency	0.555	0.445
E53.0 Riboflavin deficiency	0.555	0.445
E75.5 Other lipid storage disorders	0.560	0.439
M12.8 Other specific arthropathies, not elsewhere classified	0.568	0.432
M12.5 Traumatic arthropathy	0.568	0.432
M12.4 Intermittent hydrarthrosis	0.568	0.432
M12.2 Villonodular synovitis (pigmented)	0.568	0.432
M12.1 Kaschin-Beck disease	0.568	0.432
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.568	0.432
E67 Other hyperalimentation	0.569	0.430
E68 Sequelae of hyperalimentation	0.569	0.430
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.582	0.418
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.582	0.418
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.582	0.418
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.582	0.418
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.582	0.418
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.582	0.418
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.582	0.418
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.582	0.418
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.582	0.418
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.582	0.418
M07.19 Arthritis mutilans (Site unspecified)	0.582	0.418
M07.18 Arthritis mutilans (Other)	0.582	0.418
M07.17 Arthritis mutilans (Ankle and foot)	0.582	0.418
M07.16 Arthritis mutilans (Lower leg)	0.582	0.418
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.582	0.418
M07.14 Arthritis mutilans (Hand)	0.582	0.418
M07.13 Arthritis mutilans (Forearm)	0.582	0.418
M07.12 Arthritis mutilans (Upper arm)	0.582	0.418
M07.11 Arthritis mutilans (Shoulder region)	0.582	0.418
M07.10 Arthritis mutilans (Multiple sites)	0.582	0.418
M07.29 Psoriatic spondylitis (Site unspecified)	0.582	0.418
M07.28 Psoriatic spondylitis (Other)	0.582	0.418
M07.27 Psoriatic spondylitis (Ankle and foot)	0.582	0.418
M07.26 Psoriatic spondylitis (Lower leg)	0.582	0.418
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.582	0.418
M07.24 Psoriatic spondylitis (Hand)	0.582	0.418
M07.23 Psoriatic spondylitis (Forearm)	0.582	0.418
M07.22 Psoriatic spondylitis (Upper arm)	0.582	0.418
M07.21 Psoriatic spondylitis (Shoulder region)	0.582	0.418
M07.20 Psoriatic spondylitis (Multiple sites)	0.582	0.418
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.582	0.418
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.582	0.418
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.582	0.418
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.582	0.418
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.582	0.418
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.582	0.418
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.582	0.418
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.582	0.418
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.582	0.418
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.582	0.418
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.582	0.418
M07.58 Arthropathy in ulcerative colitis (Other)	0.582	0.418
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.582	0.418
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.582	0.418
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.582	0.418
M07.54 Arthropathy in ulcerative colitis (Hand)	0.582	0.418
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.582	0.418
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.582	0.418
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.582	0.418
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.582	0.418
M07.69 Other enteropathic arthropathies (Site unspecified)	0.582	0.418
M07.68 Other enteropathic arthropathies (Other)	0.582	0.418
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.582	0.418
M07.66 Other enteropathic arthropathies (Lower leg)	0.582	0.418
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.582	0.418
M07.64 Other enteropathic arthropathies (Hand)	0.582	0.418
M07.63 Other enteropathic arthropathies (Forearm)	0.582	0.418
M07.62 Other enteropathic arthropathies (Upper arm)	0.582	0.418
M07.61 Other enteropathic arthropathies (Shoulder region)	0.582	0.418
M07.60 Other enteropathic arthropathies (Multiple sites)	0.582	0.418
E61 Deficiency of other nutrient elements	0.590	0.410
E11.6 With other specified complications	0.592	0.408

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations