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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9260489
log Bayes Factor = 97.3753
Chromosome 6   position 29,920,332  (GRCh37) Explore rs9260489 on Ensembl!
Variant rs9260489 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E89.0 Postprocedural hypothyroidism
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.000 0.000 1.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.024 0.976
E06 Thyroiditis
0.000 0.029 0.971
F31 Bipolar affective disorder
0.000 0.030 0.970
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.031 0.969
F30-F39 Mood [affective] disorders
0.000 0.041 0.959
I71 Aortic aneurysm and dissection
0.000 0.044 0.956
Chapter V Mental and behavioural disorders
0.000 0.045 0.955
E89.2 Postprocedural hypoparathyroidism
0.000 0.047 0.953
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.047 0.953
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.048 0.952
I77 Other disorders of arteries and arterioles
0.000 0.056 0.944
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.057 0.943
E83.5 Disorders of calcium metabolism
0.000 0.063 0.937
I74 Arterial embolism and thrombosis
0.000 0.067 0.933
Chapter IX Diseases of the circulatory system
0.000 0.069 0.931
# Top node
0.000 0.070 0.930
Chapter VI Diseases of the nervous system
0.000 0.075 0.925
L40-L45 Papulosquamous disorders
0.000 0.079 0.921
L40 Psoriasis
0.000 0.080 0.920
F01 Vascular dementia
0.000 0.081 0.919
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.082 0.918
G30-G32 Other degenerative diseases of the nervous system
0.000 0.083 0.917
E06.9 Thyroiditis, unspecified
0.000 0.083 0.917
L40.9 Psoriasis, unspecified
0.000 0.090 0.910
I77.1 Stricture of artery
0.000 0.093 0.907
F02 Dementia in other diseases classified elsewhere
0.000 0.094 0.906
F31.9 Bipolar affective disorder, unspecified
0.000 0.094 0.906
E06.3 Autoimmune thyroiditis
0.000 0.098 0.902
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.108 0.892
I60-I69 Cerebrovascular diseases
0.000 0.113 0.887
F01.9 Vascular dementia, unspecified
0.000 0.117 0.883
I73 Other peripheral vascular diseases
0.000 0.122 0.878
F05.9 Delirium, unspecified
0.000 0.124 0.876
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.124 0.876
G30 Alzheimer's disease
0.000 0.126 0.874
L40.5 Arthropathic psoriasis
0.000 0.127 0.873
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.129 0.871
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.133 0.867
L43 Lichen planus
0.000 0.133 0.867
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.135 0.865
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.138 0.862
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.143 0.857
I72 Other aneurysm
0.000 0.147 0.853
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.147 0.853
G30.9 Alzheimer's disease, unspecified
0.000 0.148 0.852
G37 Other demyelinating diseases of central nervous system
0.000 0.152 0.848
I70 Atherosclerosis
0.000 0.152 0.848
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.156 0.844
I77.2 Rupture of artery
0.000 0.156 0.844
I99 Other and unspecified disorders of circulatory system
0.000 0.157 0.843
I62 Other nontraumatic intracranial haemorrhage
0.000 0.160 0.840
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.160 0.840
L89 Decubitus ulcer
0.000 0.160 0.840
F80-F89 Disorders of psychological development
0.000 0.161 0.839
L43.9 Lichen planus, unspecified
0.000 0.168 0.832
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.169 0.831
I73.9 Peripheral vascular disease, unspecified
0.000 0.174 0.826
F02.8 Dementia in other specified diseases classified elsewhere
0.000 0.175 0.825
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.178 0.822
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.179 0.821
F31.8 Other bipolar affective disorders
0.000 0.183 0.817
L10-L14 Bullous disorders
0.000 0.187 0.813
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.188 0.812
F39 Unspecified mood [affective] disorder
0.000 0.189 0.811
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.194 0.806
L93 Lupus erythematosus
0.000 0.202 0.798
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.203 0.797
I65.2 Occlusion and stenosis of carotid artery
0.000 0.208 0.792
E84 Cystic fibrosis
0.000 0.213 0.787
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.215 0.785
I77.6 Arteritis, unspecified
0.000 0.226 0.774
I69 Sequelae of cerebrovascular disease
0.000 0.228 0.772
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.229 0.771
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.234 0.766
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.235 0.765
L89.3 Stage IV decubitus ulcer
0.000 0.236 0.764
F80 Specific developmental disorders of speech and language
0.000 0.245 0.755
L83 Acanthosis nigricans
0.000 0.247 0.753
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.248 0.752
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.249 0.751
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.250 0.750
F50 Eating disorders
0.000 0.251 0.749
I72.8 Aneurysm of other specified arteries
0.000 0.251 0.749
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.251 0.749
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.252 0.748
E89.4 Postprocedural ovarian failure
0.000 0.252 0.748
F02.0 Dementia in Pick's disease
0.000 0.252 0.748
F01.1 Multi-infarct dementia
0.000 0.258 0.742
G31.2 Degeneration of nervous system due to alcohol
0.000 0.258 0.742
I72.4 Aneurysm of artery of lower extremity
0.000 0.258 0.742
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.261 0.739
L93.0 Discoid lupus erythematosus
0.000 0.262 0.738
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.265 0.735
E03.8 Other specified hypothyroidism
0.000 0.266 0.734
F02.3 Dementia in Parkinson's disease
0.000 0.266 0.734
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.270 0.730
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.278 0.722
L40.3 Pustulosis palmaris et plantaris
0.000 0.279 0.721
I74.8 Embolism and thrombosis of other arteries
0.000 0.281 0.718
E70 Disorders of aromatic amino-acid metabolism
0.000 0.282 0.718
E40-E46 Malnutrition
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E76 Disorders of glycosaminoglycan metabolism
0.000 0.283 0.717
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.283 0.717
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.283 0.717
E83.8 Other disorders of mineral metabolism
0.000 0.283 0.717
E83.2 Disorders of zinc metabolism
0.000 0.283 0.717
E83.0 Disorders of copper metabolism
0.000 0.283 0.717
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.283 0.717
E80.4 Gilbert's syndrome
0.000 0.284 0.716
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.285 0.715
I72.3 Aneurysm of iliac artery
0.000 0.286 0.714
G31.8 Other specified degenerative diseases of nervous system
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
L81 Other disorders of pigmentation
0.000 0.288 0.712
L89.2 Stage III decubitus ulcer
0.000 0.288 0.712
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.290 0.710
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.291 0.709
I70.8 Atherosclerosis of other arteries
0.000 0.291 0.709
G31.0 Circumscribed brain atrophy
0.000 0.292 0.708
L40.1 Generalised pustular psoriasis
0.000 0.293 0.707
F80.1 Expressive language disorder
0.000 0.294 0.706
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.297 0.703
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.298 0.702
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.298 0.702
I70.0 Atherosclerosis of aorta
0.000 0.299 0.701
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.299 0.701
I62.1 Nontraumatic extradural haemorrhage
0.000 0.299 0.701
E80.1 Porphyria cutanea tarda
0.000 0.302 0.698
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.302 0.698
G30.0 Alzheimer's disease with early onset
0.000 0.303 0.697
F00 Dementia in Alzheimer's disease
0.000 0.303 0.697
E06.4 Drug-induced thyroiditis
0.000 0.304 0.696
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.304 0.696
E06.0 Acute thyroiditis
0.000 0.304 0.696
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.305 0.695
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.306 0.694
E73 Lactose intolerance
0.000 0.307 0.693
L13 Other bullous disorders
0.000 0.307 0.693
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.308 0.692
I67 Other cerebrovascular diseases
0.000 0.309 0.691
E89.1 Postprocedural hypoinsulinaemia
0.000 0.310 0.690
F31.7 Bipolar affective disorder, currently in remission
0.000 0.310 0.690
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.310 0.689
F38 Other mood [affective] disorders
0.000 0.311 0.689
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.311 0.689
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.312 0.688
F32 Depressive episode
0.000 0.313 0.687
F03 Unspecified dementia
0.000 0.314 0.686
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.315 0.685
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.315 0.685
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.315 0.685
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.000 0.317 0.683
I00-I02 Acute rheumatic fever
0.000 0.317 0.682
I77.3 Arterial fibromuscular dysplasia
0.000 0.321 0.679
I77.5 Necrosis of artery
0.000 0.323 0.677
I77.4 Coeliac artery compression syndrome
0.000 0.323 0.677
E80.6 Other disorders of bilirubin metabolism
0.000 0.324 0.676
E06.5 Other chronic thyroiditis
0.000 0.325 0.675
E84.9 Cystic fibrosis, unspecified
0.000 0.325 0.675
F05.0 Delirium not superimposed on dementia, so described
0.000 0.327 0.673
I63 Cerebral infarction
0.000 0.328 0.672
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.332 0.667
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.333 0.667
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.334 0.665
L40.4 Guttate psoriasis
0.000 0.335 0.664
F60-F69 Disorders of adult personality and behaviour
0.000 0.336 0.664
F30 Manic episode
0.000 0.336 0.664
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.337 0.663
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.340 0.660
L40.2 Acrodermatitis continua
0.000 0.340 0.660
F50.9 Eating disorder, unspecified
0.000 0.341 0.659
L93.2 Other local lupus erythematosus
0.000 0.341 0.659
F01.8 Other vascular dementia
0.000 0.341 0.659
F01.3 Mixed cortical and subcortical vascular dementia
0.000 0.341 0.659
F01.2 Subcortical vascular dementia
0.000 0.341 0.659
F01.0 Vascular dementia of acute onset
0.000 0.341 0.659
L88 Pyoderma gangrenosum
0.000 0.342 0.658
E77 Disorders of glycoprotein metabolism
0.000 0.344 0.656
L81.9 Disorder of pigmentation, unspecified
0.000 0.344 0.656
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.000 0.350 0.649
F02.2 Dementia in Huntington's disease
0.000 0.350 0.649
F02.1 Dementia in Creutzfeldt-Jakob disease
0.000 0.350 0.649
G36 Other acute disseminated demyelination
0.000 0.353 0.647
E79 Disorders of purine and pyrimidine metabolism
0.000 0.358 0.642
E74 Other disorders of carbohydrate metabolism
0.000 0.359 0.641
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.361 0.639
L11 Other acantholytic disorders
0.000 0.362 0.638
E05.8 Other thyrotoxicosis
0.000 0.364 0.636
L42 Pityriasis rosea
0.000 0.364 0.636
L40.0 Psoriasis vulgaris
0.000 0.365 0.635
F50.2 Bulimia nervosa
0.000 0.366 0.634
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.367 0.633
I70.9 Generalised and unspecified atherosclerosis
0.000 0.368 0.632
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.368 0.632
F09 Unspecified organic or symptomatic mental disorder
0.000 0.369 0.631
F81 Specific developmental disorders of scholastic skills
0.000 0.371 0.629
I79.1 Aortitis in diseases classified elsewhere
0.000 0.372 0.628
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.372 0.628
L95.9 Vasculitis limited to skin, unspecified
0.000 0.373 0.627
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.375 0.624
I27 Other pulmonary heart diseases
0.000 0.376 0.624
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.378 0.622
L43.3 Subacute (active) lichen planus
0.000 0.378 0.622
L43.2 Lichenoid drug reaction
0.000 0.378 0.622
L43.1 Bullous lichen planus
0.000 0.378 0.622
L43.0 Hypertrophic lichen planus
0.000 0.378 0.622
I67.8 Other specified cerebrovascular diseases
0.000 0.379 0.621
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.379 0.620
E80.5 Crigler-Najjar syndrome
0.000 0.379 0.620
E80.3 Defects of catalase and peroxydase
0.000 0.379 0.620
E80.0 Hereditary erythropoietic porphyria
0.000 0.379 0.620
L44 Other papulosquamous disorders
0.000 0.380 0.619
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.381 0.619
E50-E64 Other nutritional deficiencies
0.000 0.381 0.619
L94 Other localised connective tissue disorders
0.000 0.382 0.618
L93.1 Subacute cutaneous lupus erythematosus
0.000 0.385 0.615
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.386 0.614
E03.1 Congenital hypothyroidism without goitre
0.000 0.387 0.613
F32.0 Mild depressive episode
0.000 0.387 0.613
I73.0 Raynaud's syndrome
0.000 0.388 0.612
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.389 0.611
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.389 0.611
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.389 0.611
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.389 0.611
I70.1 Atherosclerosis of renal artery
0.000 0.389 0.611
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.390 0.610
E72 Other disorders of amino-acid metabolism
0.000 0.391 0.609
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.391 0.609
L12 Pemphigoid
0.000 0.392 0.608
L13.0 Dermatitis herpetiformis
0.000 0.392 0.608
G37.5 Concentric sclerosis [Balo]
0.000 0.392 0.608
G37.4 Subacute necrotising myelitis
0.000 0.392 0.608
G37.2 Central pontine myelinolysis
0.000 0.392 0.608
G37.1 Central demyelination of corpus callosum
0.000 0.392 0.608
G37.0 Diffuse sclerosis
0.000 0.392 0.608
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.393 0.606
I72.9 Aneurysm of unspecified site
0.000 0.397 0.603
F50.0 Anorexia nervosa
0.000 0.397 0.603
L87 Transepidermal elimination disorders
0.000 0.398 0.602
L86 Keratoderma in diseases classified elsewhere
0.000 0.398 0.602
L41 Parapsoriasis
0.000 0.398 0.602
F89 Unspecified disorder of psychological development
0.000 0.399 0.601
F88 Other disorders of psychological development
0.000 0.399 0.601
F83 Mixed specific developmental disorders
0.000 0.399 0.601
F82 Specific developmental disorder of motor function
0.000 0.399 0.601
F70-F79 Mental retardation
0.000 0.401 0.599
I72.1 Aneurysm of artery of upper extremity
0.000 0.402 0.598
L40.8 Other psoriasis
0.000 0.402 0.598
L10 Pemphigus
0.000 0.403 0.597
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.404 0.596
L43.8 Other lichen planus
0.000 0.404 0.595
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.405 0.595
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.408 0.592
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.411 0.589
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.412 0.588
I27.2 Other secondary pulmonary hypertension
0.000 0.412 0.588
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.414 0.586
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.415 0.585
L14 Bullous disorders in diseases classified elsewhere
0.000 0.417 0.583
F34 Persistent mood [affective] disorders
0.000 0.418 0.582
E06.1 Subacute thyroiditis
0.000 0.419 0.581
G30.8 Other Alzheimer's disease
0.000 0.419 0.581
I65.1 Occlusion and stenosis of basilar artery
0.000 0.420 0.580
G03 Meningitis due to other and unspecified causes
0.000 0.421 0.579
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.424 0.576
I60 Subarachnoid haemorrhage
0.000 0.427 0.573
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.429 0.571
F55 Abuse of non-dependence-producing substances
0.000 0.429 0.571
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.000 0.429 0.571
L81.8 Other specified disorders of pigmentation
0.000 0.429 0.571
L81.0 Postinflammatory hyperpigmentation
0.000 0.429 0.571
F84 Pervasive developmental disorders
0.000 0.430 0.570
E80.2 Other porphyria
0.000 0.433 0.567
E84.8 Cystic fibrosis with other manifestations
0.000 0.435 0.564
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.435 0.564
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.440 0.560
F00.0 Dementia in Alzheimer's disease with early onset
0.000 0.440 0.560
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.441 0.559
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.443 0.557
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.444 0.556
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.444 0.556
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.448 0.552
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.450 0.549
F69 Unspecified disorder of adult personality and behaviour
0.000 0.452 0.547
F51 Nonorganic sleep disorders
0.000 0.456 0.543
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.457 0.543
F80.9 Developmental disorder of speech and language, unspecified
0.000 0.458 0.542
F80.8 Other developmental disorders of speech and language
0.000 0.458 0.542
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.000 0.458 0.542
F80.0 Specific speech articulation disorder
0.000 0.458 0.542
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.461 0.539
F99-F99 Unspecified mental disorder
0.000 0.461 0.539
F30.9 Manic episode, unspecified
0.000 0.462 0.538
F50.8 Other eating disorders
0.000 0.463 0.537
F50.5 Vomiting associated with other psychological disturbances
0.000 0.463 0.537
F50.4 Overeating associated with other psychological disturbances
0.000 0.463 0.537
F50.3 Atypical bulimia nervosa
0.000 0.463 0.537
F50.1 Atypical anorexia nervosa
0.000 0.463 0.537
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.464 0.536
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.464 0.536
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.468 0.532
I67.1 Cerebral aneurysm, nonruptured
0.000 0.470 0.530
F61 Mixed and other personality disorders
0.000 0.470 0.530
E89.5 Postprocedural testicular hypofunction
0.001 0.471 0.528
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.471 0.528
F07.2 Postconcussional syndrome
0.000 0.472 0.528
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.473 0.527
B37 Candidiasis
0.000 0.473 0.527
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.474 0.526
B37.9 Candidiasis, unspecified
0.000 0.477 0.523
I74.5 Embolism and thrombosis of iliac artery
0.000 0.477 0.523
F05.8 Other delirium
0.000 0.479 0.521
B37.8 Candidiasis of other sites
0.000 0.479 0.521
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.482 0.518
E70.3 Albinism
0.000 0.484 0.516
E46 Unspecified protein-energy malnutrition
0.000 0.484 0.516
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.485 0.515
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.485 0.515
E70.2 Disorders of tyrosine metabolism
0.000 0.485 0.515
E70.1 Other hyperphenylalaninaemias
0.000 0.485 0.515
E70.0 Classical phenylketonuria
0.000 0.485 0.515
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.485 0.515
E45 Retarded development following protein-energy malnutrition
0.000 0.485 0.515
E43 Unspecified severe protein-energy malnutrition
0.000 0.485 0.515
E42 Marasmic kwashiorkor
0.000 0.485 0.515
E41 Nutritional marasmus
0.000 0.485 0.515
E40 Kwashiorkor
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E71.3 Disorders of fatty-acid metabolism
0.000 0.486 0.514
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.486 0.514
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.486 0.514
E71.0 Maple-syrup-urine disease
0.000 0.486 0.514
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.486 0.514
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.486 0.514
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.486 0.514
E76.2 Other mucopolysaccharidoses
0.000 0.486 0.514
E76.1 Mucopolysaccharidosis, type II
0.000 0.486 0.514
E76.0 Mucopolysaccharidosis, type I
0.000 0.486 0.514
I27.9 Pulmonary heart disease, unspecified
0.000 0.486 0.514
F38.0 Other single mood [affective] disorders
0.000 0.488 0.512
K90 Intestinal malabsorption
0.000 0.489 0.511
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.489 0.511
L81.7 Pigmented purpuric dermatosis
0.000 0.489 0.510
L81.6 Other disorders of diminished melanin formation
0.000 0.489 0.510
L81.5 Leukoderma, not elsewhere classified
0.000 0.489 0.510
L81.3 Cafe au lait spots
0.000 0.489 0.510
L81.1 Chloasma
0.000 0.489 0.510
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.492 0.508
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.492 0.508
E07 Other disorders of thyroid
0.000 0.494 0.506
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.494 0.505
I00 Rheumatic fever without mention of heart involvement
0.000 0.495 0.504
L94.2 Calcinosis cutis
0.000 0.496 0.504
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.000 0.496 0.503
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.496 0.503
F07.1 Postencephalitic syndrome
0.000 0.496 0.503
L95.1 Erythema elevatum diutinum
0.000 0.497 0.503
L95.0 Livedoid vasculitis
0.000 0.497 0.503
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.497 0.502
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.000 0.497 0.502
F93 Emotional disorders with onset specific to childhood
0.000 0.497 0.502
F92 Mixed disorders of conduct and emotions
0.000 0.497 0.502
F91 Conduct disorders
0.000 0.497 0.502
F90 Hyperkinetic disorders
0.000 0.497 0.502
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.498 0.502
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.500 0.500
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.501 0.499
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.501 0.498
I97.0 Postcardiotomy syndrome
0.000 0.501 0.498
I69.3 Sequelae of cerebral infarction
0.000 0.502 0.498
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.502 0.498
E73.8 Other lactose intolerance
0.000 0.503 0.497
E73.1 Secondary lactase deficiency
0.000 0.503 0.497
E73.0 Congenital lactase deficiency
0.000 0.503 0.497
F80.2 Receptive language disorder
0.000 0.503 0.497
L13.9 Bullous disorder, unspecified
0.000 0.503 0.497
L13.8 Other specified bullous disorders
0.000 0.503 0.497
L13.1 Subcorneal pustular dermatitis
0.000 0.503 0.497
F07.0 Organic personality disorder
0.000 0.503 0.497
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.503 0.497
L11.0 Acquired keratosis follicularis
0.000 0.503 0.497
I67.5 Moyamoya disease
0.000 0.505 0.495
I67.4 Hypertensive encephalopathy
0.000 0.505 0.495
I67.3 Progressive vascular leukoencephalopathy
0.000 0.505 0.495
E15 Nondiabetic hypoglycaemic coma
0.000 0.505 0.494
F38.1 Other recurrent mood [affective] disorders
0.000 0.506 0.494
L20-L30 Dermatitis and eczema
0.000 0.506 0.494
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.508 0.492
B37.0 Candidal stomatitis
0.000 0.509 0.491
I71.0 Dissection of aorta [any part]
0.000 0.510 0.490
I02 Rheumatic chorea
0.000 0.510 0.489
I01 Rheumatic fever with heart involvement
0.000 0.510 0.489
F00.1 Dementia in Alzheimer's disease with late onset
0.000 0.511 0.488
F95 Tic disorders
0.000 0.513 0.487
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.514 0.486
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.514 0.485
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.517 0.483
G70-G73 Diseases of myoneural junction and muscle
0.000 0.517 0.483
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.518 0.481
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.518 0.481
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.520 0.480
P10-P15 Birth trauma
0.000 0.520 0.479
E51 Thiamine deficiency
0.000 0.521 0.479
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.521 0.479
I77.8 Other specified disorders of arteries and arterioles
0.000 0.521 0.479
P90-P96 Other disorders originating in the perinatal period
0.000 0.521 0.479
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.521 0.479
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.521 0.479
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.521 0.479
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.521 0.479
P35-P39 Infections specific to the perinatal period
0.000 0.521 0.479
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.521 0.479
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.521 0.479
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.521 0.479
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.521 0.479
L11.1 Transient acantholytic dermatosis [Grover]
0.000 0.522 0.478
F68 Other disorders of adult personality and behaviour
0.000 0.522 0.477
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.523 0.477
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.524 0.476
F65 Disorders of sexual preference
0.000 0.524 0.476
F63 Habit and impulse disorders
0.000 0.524 0.476
F30.8 Other manic episodes
0.000 0.524 0.476
L89.1 Stage II decubitus ulcer
0.000 0.524 0.476
F38.8 Other specified mood [affective] disorders
0.000 0.524 0.475
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.525 0.475
F00.9 Dementia in Alzheimer's disease, unspecified
0.000 0.525 0.475
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.525 0.475
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.000 0.526 0.474
E73.9 Lactose intolerance, unspecified
0.000 0.526 0.474
L94.8 Other specified localised connective tissue disorders
0.000 0.529 0.471
L80 Vitiligo
0.000 0.530 0.470
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.530 0.470
E77.1 Defects in glycoprotein degradation
0.000 0.530 0.470
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.530 0.470
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.531 0.469
E16 Other disorders of pancreatic internal secretion
0.000 0.532 0.467
L28 Lichen simplex chronicus and prurigo
0.000 0.533 0.467
G03.9 Meningitis, unspecified
0.000 0.534 0.466
I72.0 Aneurysm of carotid artery
0.000 0.535 0.465
G36.9 Acute disseminated demyelination, unspecified
0.000 0.536 0.464
G36.8 Other specified acute disseminated demyelination
0.000 0.536 0.464
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.536 0.464
E78.6 Lipoprotein deficiency
0.000 0.536 0.464
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.537 0.463
F30.1 Mania without psychotic symptoms
0.000 0.537 0.462
L12.9 Pemphigoid, unspecified
0.000 0.539 0.461
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.539 0.460
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.539 0.460
E79.1 Lesch-Nyhan syndrome
0.000 0.539 0.460
E55 Vitamin D deficiency
0.000 0.540 0.460
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.540 0.460
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.540 0.460
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.540 0.460
E74.2 Disorders of galactose metabolism
0.000 0.540 0.460
E74.1 Disorders of fructose metabolism
0.000 0.540 0.460
G30.1 Alzheimer's disease with late onset
0.001 0.542 0.458
L11.9 Acantholytic disorder, unspecified
0.000 0.542 0.457
L11.8 Other specified acantholytic disorders
0.000 0.542 0.457
E74.0 Glycogen storage disease
0.000 0.542 0.457
E65-E68 Obesity and other hyperalimentation
0.000 0.546 0.454
B37.3 Candidiasis of vulva and vagina
0.000 0.546 0.454
F64 Gender identity disorders
0.000 0.546 0.454
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.547 0.453
F81.8 Other developmental disorders of scholastic skills
0.000 0.549 0.451
F81.3 Mixed disorder of scholastic skills
0.000 0.549 0.451
F81.2 Specific disorder of arithmetical skills
0.000 0.549 0.451
F81.1 Specific spelling disorder
0.000 0.549 0.451
F81.0 Specific reading disorder
0.000 0.549 0.451
I27.8 Other specified pulmonary heart diseases
0.000 0.549 0.451
L10.9 Pemphigus, unspecified
0.000 0.549 0.450

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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