TreeWAS – Variant ID: rs9261418

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E10 Insulin-dependent diabetes mellitus	0.000	0.007	0.993
E10.9 Without complications	0.000	0.010	0.990
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.010	0.990
E10-E14 Diabetes mellitus	0.000	0.011	0.989
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.011	0.989
E05.9 Thyrotoxicosis, unspecified	0.000	0.024	0.976
E10.1 With ketoacidosis	0.000	0.050	0.950
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.080	0.920
E06 Thyroiditis	0.000	0.104	0.896
E10.4 With neurological complications	0.000	0.119	0.881
E10.5 With peripheral circulatory complications	0.000	0.135	0.865
E03.8 Other specified hypothyroidism	0.000	0.139	0.861
E06.3 Autoimmune thyroiditis	0.000	0.161	0.839
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.188	0.812
L40.0 Psoriasis vulgaris	0.809	0.191	0.000
L40.8 Other psoriasis	0.792	0.208	0.000
L40.1 Generalised pustular psoriasis	0.761	0.239	0.000
E13 Other specified diabetes mellitus	0.000	0.243	0.757
E20-E35 Disorders of other endocrine glands	0.000	0.257	0.743
E10.2 With renal complications	0.000	0.271	0.729
E05.8 Other thyrotoxicosis	0.000	0.276	0.724
E10.8 With unspecified complications	0.000	0.277	0.723
T36-T50 Poisoning by drugs, medicaments and biological substances	0.721	0.279	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.284	0.716
E27 Other disorders of adrenal gland	0.000	0.284	0.716
E10.7 With multiple complications	0.000	0.288	0.712
E10.6 With other specified complications	0.000	0.288	0.712
E10.0 With coma	0.000	0.288	0.712
E50-E64 Other nutritional deficiencies	0.000	0.290	0.710
E05.5 Thyroid crisis or storm	0.000	0.290	0.709
E05.4 Thyrotoxicosis factitia	0.000	0.290	0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.290	0.709
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.290	0.709
E12 Malnutrition-related diabetes mellitus	0.000	0.291	0.709
E10.3 With ophthalmic complications	0.000	0.291	0.709
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.706	0.294	0.000
E40-E46 Malnutrition	0.000	0.295	0.704
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.698	0.302	0.000
E14 Unspecified diabetes mellitus	0.000	0.307	0.693
E16 Other disorders of pancreatic internal secretion	0.000	0.314	0.686
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.680	0.320	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.679	0.321	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.675	0.325	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.338	0.662
T43.5 Other and unspecified antipsychotics and neuroleptics	0.645	0.355	0.000
E14.3 With ophthalmic complications	0.000	0.356	0.644
E06.5 Other chronic thyroiditis	0.000	0.358	0.642
E06.4 Drug-induced thyroiditis	0.000	0.358	0.642
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.358	0.642
E06.1 Subacute thyroiditis	0.000	0.358	0.642
E06.0 Acute thyroiditis	0.000	0.358	0.642
T39.1 4-Aminophenol derivatives	0.642	0.358	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.638	0.362	0.000
E13.9 Without complications	0.000	0.369	0.631
T43.4 Butyrophenone and thioxanthene neuroleptics	0.615	0.385	0.000
E34 Other endocrine disorders	0.000	0.386	0.614
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.387	0.613
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.612	0.388	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.609	0.391	0.000
T42.4 Benzodiazepines	0.601	0.399	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.399	0.601
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.402	0.598
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.592	0.408	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.408	0.592
E15 Nondiabetic hypoglycaemic coma	0.000	0.418	0.582
T43.3 Phenothiazine antipsychotics and neuroleptics	0.575	0.425	0.000
T39.0 Salicylates	0.572	0.428	0.000
T36 Poisoning by systemic antibiotics	0.570	0.430	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.565	0.435	0.000
E07 Other disorders of thyroid	0.000	0.436	0.564
E06.9 Thyroiditis, unspecified	0.000	0.437	0.563
E65-E68 Obesity and other hyperalimentation	0.000	0.441	0.559
T46.1 Calcium-channel blockers	0.557	0.443	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.554	0.446	0.000
E29 Testicular dysfunction	0.000	0.449	0.551
E20 Hypoparathyroidism	0.000	0.450	0.550
E24 Cushing's syndrome	0.000	0.450	0.550
E22 Hyperfunction of pituitary gland	0.000	0.453	0.547
T42.0 Hydantoin derivatives	0.545	0.455	0.000
E13.8 With unspecified complications	0.000	0.457	0.543
E13.7 With multiple complications	0.000	0.457	0.543
E13.6 With other specified complications	0.000	0.457	0.543
E13.5 With peripheral circulatory complications	0.000	0.457	0.543
E13.4 With neurological complications	0.000	0.457	0.543
E13.2 With renal complications	0.000	0.457	0.543
E13.1 With ketoacidosis	0.000	0.457	0.543
E13.0 With coma	0.000	0.457	0.543
T46.4 Angiotensin-converting-enzyme inhibitors	0.542	0.458	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.536	0.464	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.465	0.535
E53 Deficiency of other B group vitamins	0.000	0.467	0.533
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.467	0.533
E32 Diseases of thymus	0.000	0.467	0.533
E31 Polyglandular dysfunction	0.000	0.467	0.533
E30 Disorders of puberty, not elsewhere classified	0.000	0.467	0.533
E25 Adrenogenital disorders	0.000	0.467	0.533
T43.6 Psychostimulants with abuse potential	0.526	0.474	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.475	0.525
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.525	0.475	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.523	0.477	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.522	0.478	0.000
M07.3 Other psoriatic arthropathies	0.521	0.478	0.001
M07.39 Other psoriatic arthropathies (Site unspecified)	0.519	0.481	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.519	0.481	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.518	0.481	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.517	0.483	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.517	0.483	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.517	0.483	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.517	0.483	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.513
E27.5 Adrenomedullary hyperfunction	0.000	0.486	0.514
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.486	0.514
E27.0 Other adrenocortical overactivity	0.000	0.486	0.514
E55 Vitamin D deficiency	0.000	0.491	0.509
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.491	0.509
E63 Other nutritional deficiencies	0.000	0.491	0.509
E56 Other vitamin deficiencies	0.000	0.491	0.509
E51 Thiamine deficiency	0.000	0.491	0.509
E50 Vitamin A deficiency	0.000	0.491	0.509
E60 Dietary zinc deficiency	0.000	0.491	0.509
E59 Dietary selenium deficiency	0.000	0.491	0.509
E58 Dietary calcium deficiency	0.000	0.491	0.509
E54 Ascorbic acid deficiency	0.000	0.491	0.509
E52 Niacin deficiency [pellagra]	0.000	0.491	0.509
E12.9 Without complications	0.000	0.492	0.508
E12.8 With unspecified complications	0.000	0.492	0.508
E12.7 With multiple complications	0.000	0.492	0.508
E12.6 With other specified complications	0.000	0.492	0.508
E12.5 With peripheral circulatory complications	0.000	0.492	0.508
E12.4 With neurological complications	0.000	0.492	0.508
E12.3 With ophthalmic complications	0.000	0.492	0.508
E12.2 With renal complications	0.000	0.492	0.508
E12.1 With ketoacidosis	0.000	0.492	0.508
E12.0 With coma	0.000	0.492	0.508
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.506	0.493	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.506	0.493	0.000
T42.3 Barbiturates	0.506	0.493	0.000
T42.2 Succinimides and oxazolidinediones	0.506	0.493	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.495	0.505
E45 Retarded development following protein-energy malnutrition	0.000	0.495	0.505
E43 Unspecified severe protein-energy malnutrition	0.000	0.495	0.505
E42 Marasmic kwashiorkor	0.000	0.495	0.505
E41 Nutritional marasmus	0.000	0.495	0.505
E40 Kwashiorkor	0.000	0.495	0.505
E46 Unspecified protein-energy malnutrition	0.000	0.499	0.501
T43.9 Psychotropic drug, unspecified	0.501	0.499	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.501	0.499	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.501	0.499	0.000
T42.1 Iminostilbenes	0.498	0.502	0.000
E14.8 With unspecified complications	0.000	0.503	0.497
E14.7 With multiple complications	0.000	0.503	0.497
E14.6 With other specified complications	0.000	0.503	0.497
E14.2 Withrenal complications	0.000	0.503	0.497
E14.0 With coma	0.000	0.503	0.497
E27.9 Disorder of adrenal gland, unspecified	0.000	0.505	0.495
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.508	0.492
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.508	0.492
E16.4 Abnormal secretion of gastrin	0.000	0.508	0.492
E16.3 Increased secretion of glucagon	0.000	0.508	0.492
E27.2 Addisonian crisis	0.000	0.510	0.490
T43.2 Other and unspecified antidepressants	0.490	0.510	0.000
T39.4 Antirheumatics, not elsewhere classified	0.488	0.512	0.000
T39.2 Pyrazolone derivatives	0.488	0.512	0.000
E04 Other non-toxic goitre	0.000	0.512	0.488
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.487	0.513	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.487	0.513	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.487	0.513	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.487	0.513	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.487	0.513	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.487	0.513	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.487	0.513	0.000
T44.0 Anticholinesterase agents	0.487	0.513	0.000
E61 Deficiency of other nutrient elements	0.000	0.518	0.482
E13.3 With ophthalmic complications	0.000	0.524	0.476
T46.5 Other antihypertensive drugs, not elsewhere classified	0.467	0.533	0.000
E14.1 With ketoacidosis	0.000	0.535	0.465
T36.0 Penicillins	0.461	0.538	0.000
T40.6 Other and unspecified narcotics	0.461	0.539	0.000
T45.0 Antiallergic and antiemetic drugs	0.460	0.540	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.458	0.542	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.458	0.542	0.000
T46.7 Peripheral vasodilators	0.458	0.542	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.458	0.542	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.458	0.542	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.458	0.542	0.000
E26 Hyperaldosteronism	0.000	0.548	0.452
T38.1 Thyroid hormones and substitutes	0.446	0.554	0.000
E16.1 Other hypoglycaemia	0.000	0.554	0.445
T43.0 Tricyclic and tetracyclic antidepressants	0.444	0.556	0.000
E34.5 Androgen resistance syndrome	0.000	0.560	0.440
E34.4 Constitutional tall stature	0.000	0.560	0.440
E34.3 Short stature, not elsewhere classified	0.000	0.560	0.440
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.560	0.440
E34.1 Other hypersecretion of intestinal hormones	0.000	0.560	0.440
E34.0 Carcinoid syndrome	0.000	0.562	0.437
T38.9 Other and unspecified hormone antagonists	0.437	0.563	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.437	0.563	0.000
T38.7 Androgens and anabolic congeners	0.437	0.563	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.437	0.563	0.000
T38.5 Other oestrogens and progestogens	0.437	0.563	0.000
T38.4 Oral contraceptives	0.437	0.563	0.000
T38.2 Antithyroid drugs	0.437	0.563	0.000
T38.0 Glucocorticoids and synthetic analogues	0.437	0.563	0.000
E34.8 Other specified endocrine disorders	0.000	0.564	0.436
E14.4 With neurological complications	0.000	0.565	0.435
M07 Psoriatic and enteropathic arthropathies	0.417	0.566	0.017
E24.9 Cushing's syndrome, unspecified	0.000	0.569	0.431
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.427	0.573	0.000
E14.5 With peripheral circulatory complications	0.000	0.573	0.426
E22.0 Acromegaly and pituitary gigantism	0.000	0.577	0.423
E22.1 Hyperprolactinaemia	0.000	0.584	0.416
E29.1 Testicular hypofunction	0.000	0.587	0.413
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.412	0.587	0.001
E20.9 Hypoparathyroidism, unspecified	0.000	0.588	0.412
T36.9 Systemic antibiotic, unspecified	0.408	0.591	0.000
T36.8 Other systemic antibiotics	0.408	0.591	0.000
T36.7 Antifungal antibiotics, systemically used	0.408	0.591	0.000
T36.6 Rifamycins	0.408	0.591	0.000
T36.5 Aminoglycosides	0.408	0.591	0.000
T36.4 Tetracyclines	0.408	0.591	0.000
T36.3 Macrolides	0.408	0.591	0.000
T36.2 Chloramphenicol group	0.408	0.591	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.408	0.591	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.593	0.407
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.405	0.595	0.000
T40.8 Lysergide [LSD]	0.405	0.595	0.000
T40.7 Cannabis (derivatives)	0.405	0.595	0.000
T40.5 Cocaine	0.405	0.595	0.000
T40.3 Methadone	0.405	0.595	0.000
T40.1 Heroin	0.405	0.595	0.000
T40.0 Opium	0.405	0.595	0.000
E07.1 Dyshormogenetic goitre	0.000	0.596	0.404
E07.0 Hypersecretion of calcitonin	0.000	0.596	0.404
M07.34 Other psoriatic arthropathies (Hand)	0.402	0.597	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.598	0.401
E67 Other hyperalimentation	0.000	0.599	0.401
E68 Sequelae of hyperalimentation	0.000	0.599	0.401
T40.2 Other opioids	0.400	0.600	0.000
T40.4 Other synthetic narcotics	0.398	0.602	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.605	0.395
E29.8 Other testicular dysfunction	0.000	0.605	0.395
E29.0 Testicular hyperfunction	0.000	0.605	0.395
E20.8 Other hypoparathyroidism	0.000	0.605	0.394
E20.1 Pseudohypoparathyroidism	0.000	0.605	0.394
E20.0 Idiopathic hypoparathyroidism	0.000	0.605	0.394
E24.8 Other Cushing's syndrome	0.000	0.606	0.394
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.606	0.394
E24.3 Ectopic ACTH syndrome	0.000	0.606	0.394
E24.2 Drug-induced Cushing's syndrome	0.000	0.606	0.394
E24.1 Nelson's syndrome	0.000	0.606	0.394
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.607	0.393
E22.8 Other hyperfunction of pituitary gland	0.000	0.607	0.393
E65 Localised adiposity	0.000	0.614	0.386
T45.9 Primarily systemic and haematological agent, unspecified	0.384	0.615	0.000
T45.8 Other primarily systemic and haematological agents	0.384	0.615	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.384	0.615	0.000
T45.6 Fibrinolysis-affecting drugs	0.384	0.615	0.000
T45.4 Iron and its compounds	0.384	0.615	0.000
T45.3 Enzymes, not elsewhere classified	0.384	0.615	0.000
T45.2 Vitamins, not elsewhere classified	0.384	0.615	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.382	0.617	0.001
E53.9 Vitamin B deficiency, unspecified	0.000	0.617	0.382
E53.1 Pyridoxine deficiency	0.000	0.617	0.382
E53.0 Riboflavin deficiency	0.000	0.617	0.382
E25.9 Adrenogenital disorder, unspecified	0.000	0.618	0.382
E25.8 Other adrenogenital disorders	0.000	0.618	0.382
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.618	0.382
E30.9 Disorder of puberty, unspecified	0.000	0.618	0.382
E30.8 Other disorders of puberty	0.000	0.618	0.382
E30.1 Precocious puberty	0.000	0.618	0.382
E30.0 Delayed puberty	0.000	0.618	0.382
E31.9 Polyglandular dysfunction, unspecified	0.000	0.618	0.382
E31.8 Other polyglandular dysfunction	0.000	0.618	0.382
E31.1 Polyglandular hyperfunction	0.000	0.618	0.382
E31.0 Autoimmune polyglandular failure	0.000	0.618	0.382
E32.9 Disease of thymus, unspecified	0.000	0.618	0.382
E32.8 Other diseases of thymus	0.000	0.618	0.382
E32.1 Abscess of thymus	0.000	0.618	0.382
E32.0 Persistent hyperplasia of thymus	0.000	0.618	0.382
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.618	0.382
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.618	0.382
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.618	0.382
T47.1 Other antacids and anti-gastric-secretion drugs	0.381	0.619	0.000
M05-M14 Inflammatory polyarthropathies	0.342	0.619	0.039
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.377	0.623	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.623	0.377
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.375	0.625	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.375	0.625	0.000
T47.7 Emetics	0.375	0.625	0.000
T47.6 Antidiarrhoeal drugs	0.375	0.625	0.000
T47.5 Digestants	0.375	0.625	0.000
T47.4 Other laxatives	0.375	0.625	0.000
T47.3 Saline and osmotic laxatives	0.375	0.625	0.000
T47.2 Stimulant laxatives	0.375	0.625	0.000
T47.0 Histamine H(2)-receptor antagonists	0.375	0.625	0.000
M07.38 Other psoriatic arthropathies (Other)	0.374	0.625	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.374	0.625	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.374	0.625	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.374	0.625	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.374	0.625	0.001
E28 Ovarian dysfunction	0.000	0.627	0.373
K90 Intestinal malabsorption	0.000	0.629	0.371
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.371	0.629	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.371	0.629	0.000
T37.5 Antiviral drugs	0.371	0.629	0.000
T37.4 Anthelminthics	0.371	0.629	0.000
T37.3 Other antiprotozoal drugs	0.371	0.629	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.371	0.629	0.000
T37.1 Antimycobacterial drugs	0.371	0.629	0.000
T37.0 Sulphonamides	0.371	0.629	0.000
T41.5 Therapeutic gases	0.371	0.629	0.000
T41.4 Anaesthetic, unspecified	0.371	0.629	0.000
T41.3 Local anaesthetics	0.371	0.629	0.000
T41.2 Other and unspecified general anaesthetics	0.371	0.629	0.000
T41.1 Intravenous anaesthetics	0.371	0.629	0.000
T41.0 Inhaled anaesthetics	0.371	0.629	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.371	0.629	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.371	0.629	0.000
T48.5 Anti-common-cold drugs	0.371	0.629	0.000
T48.4 Expectorants	0.371	0.629	0.000
T48.3 Antitussives	0.371	0.629	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.371	0.629	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.371	0.629	0.000
T48.0 Oxytocic drugs	0.371	0.629	0.000
T49.9 Topical agent, unspecified	0.371	0.629	0.000
T49.8 Other topical agents	0.371	0.629	0.000
T49.7 Dental drugs, topically applied	0.371	0.629	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.371	0.629	0.000
T49.5 Ophthalmological drugs and preparations	0.371	0.629	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.371	0.629	0.000
T49.3 Emollients, demulcents and protectants	0.371	0.629	0.000
T49.2 Local astringents and local detergents	0.371	0.629	0.000
T49.1 Antipruritics	0.371	0.629	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.371	0.629	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.632	0.368
E55.9 Vitamin D deficiency, unspecified	0.000	0.634	0.365
E55.0 Rickets, active	0.000	0.635	0.365
E50.9 Vitamin A deficiency, unspecified	0.000	0.635	0.365
E50.8 Other manifestations of vitamin A deficiency	0.000	0.635	0.365
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.635	0.365
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.635	0.365
E50.5 Vitamin A deficiency with night blindness	0.000	0.635	0.365
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.635	0.365
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.635	0.365
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.635	0.365
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.635	0.365
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.635	0.365
E51.9 Thiamine deficiency, unspecified	0.000	0.635	0.365
E51.8 Other manifestations of thiamine deficiency	0.000	0.635	0.365
E51.2 Wernicke's encephalopathy	0.000	0.635	0.365
E51.1 Beriberi	0.000	0.635	0.365
E56.9 Vitamin deficiency, unspecified	0.000	0.635	0.365
E56.8 Deficiency of other vitamins	0.000	0.635	0.365
E56.1 Deficiency of vitamin K	0.000	0.635	0.365
E56.0 Deficiency of vitamin E	0.000	0.635	0.365
E63.9 Nutritional deficiency, unspecified	0.000	0.635	0.365
E63.8 Other specified nutritional deficiencies	0.000	0.635	0.365
E63.1 Imbalance of constituents of food intake	0.000	0.635	0.365
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.635	0.365
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.635	0.365
E64.8 Sequelae of other nutritional deficiencies	0.000	0.635	0.365
E64.3 Sequelae of rickets	0.000	0.635	0.365
E64.2 Sequelae of vitamin C deficiency	0.000	0.635	0.365
E64.1 Sequelae of vitamin A deficiency	0.000	0.635	0.365
E64.0 Sequelae of protein-energy malnutrition	0.000	0.635	0.365
E44.1 Mild protein-energy malnutrition	0.000	0.638	0.362
E44.0 Moderate protein-energy malnutrition	0.000	0.638	0.362
E07.9 Disorder of thyroid, unspecified	0.000	0.640	0.360
E04.0 Non-toxic diffuse goitre	0.000	0.650	0.350
E04.8 Other specified non-toxic goitre	0.000	0.650	0.350
M50 Cervical disk disorders	0.347	0.653	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.654	0.346
E61.8 Deficiency of other specified nutrient elements	0.000	0.654	0.346
E61.7 Deficiency of multiple nutrient elements	0.000	0.654	0.346
E61.6 Vanadium deficiency	0.000	0.654	0.346
E61.5 Molybdenum deficiency	0.000	0.654	0.346
E61.4 Chromium deficiency	0.000	0.654	0.346
E61.3 Manganese deficiency	0.000	0.654	0.346
E61.0 Copper deficiency	0.000	0.654	0.346
E61.1 Iron deficiency	0.000	0.655	0.345
M50.3 Other cervical disk degeneration	0.344	0.656	0.000
T45.5 Anticoagulants	0.343	0.657	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.658	0.342
M86-M90 Other osteopathies	0.340	0.660	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.336	0.664	0.000
M50-M54 Other dorsopathies	0.332	0.668	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.329	0.670	0.000
M50.1 Cervical disk disorder with radiculopathy	0.329	0.671	0.000
M89 Other disorders of bone	0.329	0.671	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.675	0.324
E26.8 Other hyperaldosteronism	0.000	0.675	0.324
E26.1 Secondary hyperaldosteronism	0.000	0.675	0.324
E61.2 Magnesium deficiency	0.000	0.680	0.320
E07.8 Other specified disorders of thyroid	0.000	0.681	0.319
M89.9 Disorder of bone, unspecified	0.319	0.681	0.000
M87 Osteonecrosis	0.313	0.687	0.000
M07.6 Other enteropathic arthropathies	0.299	0.689	0.012
M07.5 Arthropathy in ulcerative colitis	0.299	0.689	0.012
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.299	0.689	0.012
M07.2 Psoriatic spondylitis	0.299	0.689	0.012
M07.1 Arthritis mutilans	0.299	0.689	0.012
M07.0 Distal interphalangeal psoriatic arthropathy	0.299	0.689	0.012
T50.8 Diagnostic agents	0.306	0.693	0.000
T50.7 Analeptics and opioid receptor antagonists	0.306	0.693	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.306	0.693	0.000
T50.5 Appetite depressants	0.306	0.693	0.000
T50.4 Drugs affecting uric acid metabolism	0.306	0.693	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.306	0.693	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.306	0.693	0.000
T50.1 Loop [high-ceiling] diuretics	0.306	0.693	0.000
T50.0 Mineralocorticoids and their antagonists	0.306	0.693	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.306	0.694	0.000
M60-M63 Disorders of muscles	0.299	0.701	0.000
M11 Other crystal arthropathies	0.273	0.705	0.022
M90 Osteopathies in diseases classified elsewhere	0.288	0.712	0.000
E67.8 Other specified hyperalimentation	0.000	0.712	0.288
E67.3 Hypervitaminosis D	0.000	0.712	0.288
E67.2 Megavitamin-B6 syndrome	0.000	0.712	0.288
E67.1 Hypercarotenaemia	0.000	0.712	0.288
E67.0 Hypervitaminosis A	0.000	0.712	0.288
E14.9 Without complications	0.000	0.712	0.288
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.287	0.713	0.000
M91-M94 Chondropathies	0.286	0.714	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.286	0.714	0.000
E66 Obesity	0.000	0.721	0.279
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.721	0.278
M87.2 Osteonecrosis due to previous trauma	0.278	0.722	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.277	0.723	0.000
M50.8 Other cervical disk disorders	0.277	0.723	0.000
M53 Other dorsopathies, not elsewhere classified	0.276	0.724	0.000
M62 Other disorders of muscle	0.275	0.725	0.000
M12 Other specific arthropathies	0.246	0.726	0.028
E04.1 Non-toxic single thyroid nodule	0.000	0.726	0.274
M09 Juvenile arthritis in diseases classified elsewhere	0.245	0.727	0.028
M08 Juvenile arthritis	0.245	0.727	0.028
M70-M79 Other soft tissue disorders	0.270	0.730	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.732	0.268
M94 Other disorders of cartilage	0.268	0.732	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.732	0.267
E28.8 Other ovarian dysfunction	0.000	0.732	0.267
E28.1 Androgen excess	0.000	0.732	0.267
E28.0 Oestrogen excess	0.000	0.732	0.267
M50.0 Cervical disk disorder with myelopathy	0.267	0.733	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.734	0.266
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.734	0.266
K90.1 Tropical sprue	0.000	0.734	0.266
M50.2 Other cervical disk displacement	0.263	0.737	0.000
M88 Paget's disease of bone [osteitis deformans]	0.262	0.738	0.000
M89.3 Hypertrophy of bone	0.260	0.740	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.260	0.740	0.000
M10 Gout	0.243	0.741	0.016
M87.9 Osteonecrosis, unspecified	0.258	0.742	0.000
M86 Osteomyelitis	0.256	0.744	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.255	0.745	0.000
K90.8 Other intestinal malabsorption	0.000	0.746	0.254
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.254	0.746	0.000
M89.0 Algoneurodystrophy	0.251	0.749	0.000
M77 Other enthesopathies	0.248	0.752	0.000
L40-L45 Papulosquamous disorders	0.238	0.753	0.009
M94.8 Other specified disorders of cartilage	0.246	0.754	0.000
E26.0 Primary hyperaldosteronism	0.001	0.756	0.244
M00-M03 Infectious arthropathies	0.244	0.756	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.756	0.244
M50.9 Cervical disk disorder, unspecified	0.241	0.759	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.236	0.763	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.236	0.764	0.000
M89.6 Osteopathy after poliomyelitis	0.236	0.764	0.000
M89.2 Other disorders of bone development and growth	0.236	0.764	0.000
M89.1 Epiphyseal arrest	0.236	0.764	0.000
M14 Arthropathies in other diseases classified elsewhere	0.202	0.766	0.032
M62.8 Other specified disorders of muscle	0.234	0.766	0.000
M87.8 Other osteonecrosis	0.231	0.769	0.000
E66.8 Other obesity	0.000	0.770	0.230
M89.99 Disorder of bone, unspecified (Site unspecified)	0.229	0.771	0.000
M89.98 Disorder of bone, unspecified (Other)	0.229	0.771	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.229	0.771	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations