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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9261578
log Bayes Factor = 24.983
Chromosome 6   position 30,192,467  (GRCh37) Explore rs9261578 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.008 0.992
K51.9 Ulcerative colitis, unspecified
0.000 0.068 0.932
K51 Ulcerative colitis
0.000 0.093 0.907
E03 Other hypothyroidism
0.000 0.116 0.884
K51.4 Pseudopolyposis of colon
0.000 0.154 0.846
L40.0 Psoriasis vulgaris
0.836 0.164 0.000
E00-E07 Disorders of thyroid gland
0.000 0.185 0.815
L40.8 Other psoriasis
0.813 0.187 0.000
K51.8 Other ulcerative colitis
0.000 0.190 0.810
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.200 0.800
E06 Thyroiditis
0.000 0.213 0.787
L40.1 Generalised pustular psoriasis
0.786 0.214 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.220 0.780
E06.3 Autoimmune thyroiditis
0.000 0.232 0.768
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.232 0.768
E03.8 Other specified hypothyroidism
0.000 0.278 0.722
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.285 0.715
K51.5 Mucosal proctocolitis
0.000 0.286 0.714
E05.9 Thyrotoxicosis, unspecified
0.000 0.300 0.700
E03.5 Myxoedema coma
0.000 0.366 0.634
E03.4 Atrophy of thyroid (acquired)
0.000 0.366 0.634
E03.3 Postinfectious hypothyroidism
0.000 0.366 0.634
E03.1 Congenital hypothyroidism without goitre
0.000 0.366 0.634
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.366 0.634
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.394 0.606
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.416 0.584
E00 Congenital iodine-deficiency syndrome
0.000 0.416 0.584
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.416 0.584
E06.5 Other chronic thyroiditis
0.000 0.436 0.564
E06.4 Drug-induced thyroiditis
0.000 0.436 0.564
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.436 0.564
E06.1 Subacute thyroiditis
0.000 0.436 0.564
E06.0 Acute thyroiditis
0.000 0.436 0.564
E05.5 Thyroid crisis or storm
0.000 0.449 0.551
E05.4 Thyrotoxicosis factitia
0.000 0.449 0.551
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.449 0.551
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.449 0.551
E06.9 Thyroiditis, unspecified
0.000 0.458 0.542
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.474 0.526
M06.9 Rheumatoid arthritis, unspecified
0.000 0.481 0.519
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.491 0.509
E05.8 Other thyrotoxicosis
0.000 0.494 0.506
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.502 0.498
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.529 0.471
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.537 0.463
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.552 0.448
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.552 0.448
E07 Other disorders of thyroid
0.000 0.573 0.427
K90 Intestinal malabsorption
0.000 0.574 0.426
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.581 0.419
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.581 0.419
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.581 0.419
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.581 0.419
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.581 0.419
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.581 0.419
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.581 0.419
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.581 0.419
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.585 0.415
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.587 0.413
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.594 0.406
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.621 0.379
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.624 0.376
M06 Other rheumatoid arthritis
0.003 0.647 0.350
K90.9 Intestinal malabsorption, unspecified
0.000 0.662 0.338
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.669 0.330
M06.4 Inflammatory polyarthropathy
0.001 0.691 0.307
E07.1 Dyshormogenetic goitre
0.000 0.694 0.306
E07.0 Hypersecretion of calcitonin
0.000 0.694 0.306
K90.3 Pancreatic steatorrhoea
0.000 0.694 0.306
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.694 0.306
K90.1 Tropical sprue
0.000 0.694 0.306
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.700 0.300
E04 Other non-toxic goitre
0.000 0.702 0.298
K90.8 Other intestinal malabsorption
0.000 0.715 0.284
L40-L45 Papulosquamous disorders
0.242 0.721 0.037
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.724 0.276
M06.0 Seronegative rheumatoid arthritis
0.002 0.735 0.264
E07.9 Disorder of thyroid, unspecified
0.000 0.741 0.259
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.742 0.257
E50-E64 Other nutritional deficiencies
0.000 0.742 0.258
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.001 0.745 0.254
M06.8 Other specified rheumatoid arthritis
0.002 0.747 0.251
M06.2 Rheumatoid bursitis
0.002 0.747 0.251
M06.1 Adult-onset Still's disease
0.002 0.747 0.251
E10-E14 Diabetes mellitus
0.000 0.747 0.253
E10 Insulin-dependent diabetes mellitus
0.000 0.750 0.250
E20-E35 Disorders of other endocrine glands
0.000 0.751 0.249
E27 Other disorders of adrenal gland
0.000 0.753 0.247
M06.3 Rheumatoid nodule
0.002 0.758 0.240
E27.1 Primary adrenocortical insufficiency
0.000 0.763 0.237
E10.1 With ketoacidosis
0.000 0.765 0.235
E07.8 Other specified disorders of thyroid
0.000 0.773 0.226
E55 Vitamin D deficiency
0.000 0.774 0.226
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.001 0.774 0.225
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.778 0.222
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.779 0.220
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.779 0.220
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.779 0.220
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.779 0.220
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.779 0.220
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.779 0.220
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.779 0.220
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.779 0.220
L30.9 Dermatitis, unspecified
0.000 0.782 0.218
E10.5 With peripheral circulatory complications
0.000 0.784 0.216
E04.8 Other specified non-toxic goitre
0.000 0.786 0.214
E27.8 Other specified disorders of adrenal gland
0.000 0.787 0.213
E10.0 With coma
0.000 0.791 0.208
E04.9 Non-toxic goitre, unspecified
0.000 0.792 0.208
E40-E46 Malnutrition
0.000 0.793 0.207
E04.0 Non-toxic diffuse goitre
0.000 0.793 0.207
M06.34 Rheumatoid nodule (Hand)
0.001 0.797 0.202
E55.9 Vitamin D deficiency, unspecified
0.000 0.797 0.203
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.798 0.202
E34 Other endocrine disorders
0.000 0.798 0.202
L44 Other papulosquamous disorders
0.173 0.800 0.027
L41 Parapsoriasis
0.173 0.800 0.027
L45 Papulosquamous disorders in diseases classified elsewhere
0.173 0.800 0.027
L42 Pityriasis rosea
0.175 0.800 0.025
E10.4 With neurological complications
0.000 0.801 0.199
E10.9 Without complications
0.000 0.804 0.196
E53 Deficiency of other B group vitamins
0.000 0.806 0.194
E10.2 With renal complications
0.000 0.809 0.190
M06.08 Seronegative rheumatoid arthritis (Other)
0.001 0.810 0.189
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.001 0.810 0.189
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.001 0.810 0.189
M06.04 Seronegative rheumatoid arthritis (Hand)
0.001 0.810 0.189
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.001 0.810 0.189
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.001 0.810 0.189
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.001 0.810 0.189
E22 Hyperfunction of pituitary gland
0.000 0.811 0.189
E29 Testicular dysfunction
0.000 0.811 0.189
E20 Hypoparathyroidism
0.000 0.812 0.188
L30 Other dermatitis
0.000 0.814 0.186
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.815 0.185
E63 Other nutritional deficiencies
0.000 0.815 0.185
E56 Other vitamin deficiencies
0.000 0.815 0.185
E51 Thiamine deficiency
0.000 0.815 0.185
E50 Vitamin A deficiency
0.000 0.815 0.185
E60 Dietary zinc deficiency
0.000 0.815 0.185
E59 Dietary selenium deficiency
0.000 0.815 0.185
E58 Dietary calcium deficiency
0.000 0.815 0.185
E54 Ascorbic acid deficiency
0.000 0.815 0.185
E52 Niacin deficiency [pellagra]
0.000 0.815 0.185
E10.8 With unspecified complications
0.000 0.817 0.183
M06.19 Adult-onset Still's disease (Site unspecified)
0.002 0.818 0.180
M06.18 Adult-onset Still's disease (Other)
0.002 0.818 0.180
M06.17 Adult-onset Still's disease (Ankle and foot)
0.002 0.818 0.180
M06.16 Adult-onset Still's disease (Lower leg)
0.002 0.818 0.180
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.002 0.818 0.180
M06.14 Adult-onset Still's disease (Hand)
0.002 0.818 0.180
M06.13 Adult-onset Still's disease (Forearm)
0.002 0.818 0.180
M06.12 Adult-onset Still's disease (Upper arm)
0.002 0.818 0.180
M06.11 Adult-onset Still's disease (Shoulder region)
0.002 0.818 0.180
M06.10 Adult-onset Still's disease (Multiple sites)
0.002 0.818 0.180
M06.29 Rheumatoid bursitis (Site unspecified)
0.002 0.818 0.180
M06.28 Rheumatoid bursitis (Other)
0.002 0.818 0.180
M06.27 Rheumatoid bursitis (Ankle and foot)
0.002 0.818 0.180
M06.26 Rheumatoid bursitis (Lower leg)
0.002 0.818 0.180
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.002 0.818 0.180
M06.24 Rheumatoid bursitis (Hand)
0.002 0.818 0.180
M06.23 Rheumatoid bursitis (Forearm)
0.002 0.818 0.180
M06.22 Rheumatoid bursitis (Upper arm)
0.002 0.818 0.180
M06.21 Rheumatoid bursitis (Shoulder region)
0.002 0.818 0.180
M06.20 Rheumatoid bursitis (Multiple sites)
0.002 0.818 0.180
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.002 0.818 0.180
M06.88 Other specified rheumatoid arthritis (Other)
0.002 0.818 0.180
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.002 0.818 0.180
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.002 0.818 0.180
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.002 0.818 0.180
M06.84 Other specified rheumatoid arthritis (Hand)
0.002 0.818 0.180
M06.83 Other specified rheumatoid arthritis (Forearm)
0.002 0.818 0.180
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.002 0.818 0.180
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.002 0.818 0.180
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.002 0.818 0.180
E12 Malnutrition-related diabetes mellitus
0.000 0.818 0.181
E13 Other specified diabetes mellitus
0.000 0.820 0.180
E10.7 With multiple complications
0.000 0.820 0.180
E10.6 With other specified complications
0.000 0.820 0.180
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.821 0.179
E32 Diseases of thymus
0.000 0.821 0.179
E31 Polyglandular dysfunction
0.000 0.821 0.179
E30 Disorders of puberty, not elsewhere classified
0.000 0.821 0.179
E25 Adrenogenital disorders
0.000 0.821 0.179
E61 Deficiency of other nutrient elements
0.000 0.821 0.179
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.001 0.821 0.177
E27.5 Adrenomedullary hyperfunction
0.000 0.822 0.177
E27.0 Other adrenocortical overactivity
0.000 0.822 0.177
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.824 0.176
E04.1 Non-toxic single thyroid nodule
0.000 0.824 0.176
E34.9 Endocrine disorder, unspecified
0.000 0.825 0.175
M06.39 Rheumatoid nodule (Site unspecified)
0.002 0.826 0.172
M06.38 Rheumatoid nodule (Other)
0.002 0.826 0.172
M06.36 Rheumatoid nodule (Lower leg)
0.002 0.826 0.172
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.002 0.826 0.172
M06.33 Rheumatoid nodule (Forearm)
0.002 0.826 0.172
M06.31 Rheumatoid nodule (Shoulder region)
0.002 0.826 0.172
E27.2 Addisonian crisis
0.000 0.835 0.165
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.001 0.837 0.162
E55.0 Rickets, active
0.000 0.838 0.162
M06.37 Rheumatoid nodule (Ankle and foot)
0.002 0.839 0.160
E27.9 Disorder of adrenal gland, unspecified
0.000 0.841 0.159
L20-L30 Dermatitis and eczema
0.000 0.842 0.158
E53.9 Vitamin B deficiency, unspecified
0.000 0.843 0.157
E65-E68 Obesity and other hyperalimentation
0.000 0.843 0.157
E22.0 Acromegaly and pituitary gigantism
0.000 0.845 0.155
M06.32 Rheumatoid nodule (Upper arm)
0.002 0.845 0.153
K50-K52 Noninfective enteritis and colitis
0.000 0.850 0.150
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.851 0.149
E45 Retarded development following protein-energy malnutrition
0.000 0.851 0.149
E43 Unspecified severe protein-energy malnutrition
0.000 0.851 0.149
E42 Marasmic kwashiorkor
0.000 0.851 0.149
E41 Nutritional marasmus
0.000 0.851 0.149
E40 Kwashiorkor
0.000 0.851 0.149
L30.8 Other specified dermatitis
0.000 0.851 0.149
M06.30 Rheumatoid nodule (Multiple sites)
0.002 0.853 0.145
E29.1 Testicular hypofunction
0.000 0.854 0.146
E15 Nondiabetic hypoglycaemic coma
0.000 0.855 0.145
E26 Hyperaldosteronism
0.000 0.855 0.145
L29 Pruritus
0.000 0.855 0.145
E34.5 Androgen resistance syndrome
0.000 0.855 0.145
E34.4 Constitutional tall stature
0.000 0.855 0.145
E34.3 Short stature, not elsewhere classified
0.000 0.855 0.145
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.855 0.145
E34.1 Other hypersecretion of intestinal hormones
0.000 0.855 0.145
E24 Cushing's syndrome
0.000 0.855 0.145
E20.9 Hypoparathyroidism, unspecified
0.000 0.856 0.144
L41.9 Parapsoriasis, unspecified
0.124 0.856 0.019
L41.8 Other parapsoriasis
0.124 0.856 0.019
L41.5 Retiform parapsoriasis
0.124 0.856 0.019
L41.4 Large plaque parapsoriasis
0.124 0.856 0.019
L41.3 Small plaque parapsoriasis
0.124 0.856 0.019
L41.2 Lymphomatoid papulosis
0.124 0.856 0.019
L41.1 Pityriasis lichenoides chronica
0.124 0.856 0.019
L41.0 Pityriasis lichenoides et varioliformis acuta
0.124 0.856 0.019
L44.9 Papulosquamous disorder, unspecified
0.124 0.856 0.019
L44.8 Other specified papulosquamous disorders
0.124 0.856 0.019
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.124 0.856 0.019
L44.3 Lichen ruber moniliformis
0.124 0.856 0.019
L44.2 Lichen striatus
0.124 0.856 0.019
L44.1 Lichen nitidus
0.124 0.856 0.019
L44.0 Pityriasis rubra pilaris
0.124 0.856 0.019
E13.9 Without complications
0.000 0.859 0.141
E46 Unspecified protein-energy malnutrition
0.000 0.859 0.140
E34.0 Carcinoid syndrome
0.000 0.861 0.139
E53.1 Pyridoxine deficiency
0.000 0.861 0.139
E53.0 Riboflavin deficiency
0.000 0.861 0.139
E34.8 Other specified endocrine disorders
0.000 0.864 0.136
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.864 0.136
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.864 0.136
E22.8 Other hyperfunction of pituitary gland
0.000 0.864 0.136
E29.9 Testicular dysfunction, unspecified
0.000 0.864 0.136
E29.8 Other testicular dysfunction
0.000 0.864 0.136
E29.0 Testicular hyperfunction
0.000 0.864 0.136
E20.8 Other hypoparathyroidism
0.000 0.865 0.135
E20.1 Pseudohypoparathyroidism
0.000 0.865 0.135
E20.0 Idiopathic hypoparathyroidism
0.000 0.865 0.135
L29.9 Pruritus, unspecified
0.000 0.865 0.135
L30.5 Pityriasis alba
0.000 0.866 0.133
L30.4 Erythema intertrigo
0.000 0.866 0.133
L30.2 Cutaneous autosensitisation
0.000 0.866 0.133
L30.1 Dyshidrosis [pompholyx]
0.000 0.866 0.133
L30.0 Nummular dermatitis
0.000 0.866 0.133
L20 Atopic dermatitis
0.000 0.866 0.133
E50.9 Vitamin A deficiency, unspecified
0.000 0.867 0.133
E50.8 Other manifestations of vitamin A deficiency
0.000 0.867 0.133
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.867 0.133
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.867 0.133
E50.5 Vitamin A deficiency with night blindness
0.000 0.867 0.133
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.867 0.133
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.867 0.133
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.867 0.133
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.867 0.133
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.867 0.133
E51.9 Thiamine deficiency, unspecified
0.000 0.867 0.133
E51.8 Other manifestations of thiamine deficiency
0.000 0.867 0.133
E51.2 Wernicke's encephalopathy
0.000 0.867 0.133
E51.1 Beriberi
0.000 0.867 0.133
E56.9 Vitamin deficiency, unspecified
0.000 0.867 0.133
E56.8 Deficiency of other vitamins
0.000 0.867 0.133
E56.1 Deficiency of vitamin K
0.000 0.867 0.133
E56.0 Deficiency of vitamin E
0.000 0.867 0.133
E63.9 Nutritional deficiency, unspecified
0.000 0.867 0.133
E63.8 Other specified nutritional deficiencies
0.000 0.867 0.133
E63.1 Imbalance of constituents of food intake
0.000 0.867 0.133
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.867 0.133
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.867 0.133
E64.8 Sequelae of other nutritional deficiencies
0.000 0.867 0.133
E64.3 Sequelae of rickets
0.000 0.867 0.133
E64.2 Sequelae of vitamin C deficiency
0.000 0.867 0.133
E64.1 Sequelae of vitamin A deficiency
0.000 0.867 0.133
E64.0 Sequelae of protein-energy malnutrition
0.000 0.867 0.133
E16 Other disorders of pancreatic internal secretion
0.000 0.868 0.132
E10.3 With ophthalmic complications
0.000 0.868 0.132
E12.9 Without complications
0.000 0.870 0.130
E12.8 With unspecified complications
0.000 0.870 0.130
E12.7 With multiple complications
0.000 0.870 0.130
E12.6 With other specified complications
0.000 0.870 0.130
E12.5 With peripheral circulatory complications
0.000 0.870 0.130
E12.4 With neurological complications
0.000 0.870 0.130
E12.3 With ophthalmic complications
0.000 0.870 0.130
E12.2 With renal complications
0.000 0.870 0.130
E12.1 With ketoacidosis
0.000 0.870 0.130
E12.0 With coma
0.000 0.870 0.130
E61.1 Iron deficiency
0.000 0.870 0.130
E13.8 With unspecified complications
0.000 0.871 0.129
E13.7 With multiple complications
0.000 0.871 0.129
E13.6 With other specified complications
0.000 0.871 0.129
E13.5 With peripheral circulatory complications
0.000 0.871 0.129
E13.4 With neurological complications
0.000 0.871 0.129
E13.2 With renal complications
0.000 0.871 0.129
E13.1 With ketoacidosis
0.000 0.871 0.129
E13.0 With coma
0.000 0.871 0.129
E25.9 Adrenogenital disorder, unspecified
0.000 0.872 0.128
E25.8 Other adrenogenital disorders
0.000 0.872 0.128
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.872 0.128
E30.9 Disorder of puberty, unspecified
0.000 0.872 0.128
E30.8 Other disorders of puberty
0.000 0.872 0.128
E30.1 Precocious puberty
0.000 0.872 0.128
E30.0 Delayed puberty
0.000 0.872 0.128
E31.9 Polyglandular dysfunction, unspecified
0.000 0.872 0.128
E31.8 Other polyglandular dysfunction
0.000 0.872 0.128
E31.1 Polyglandular hyperfunction
0.000 0.872 0.128
E31.0 Autoimmune polyglandular failure
0.000 0.872 0.128
E32.9 Disease of thymus, unspecified
0.000 0.872 0.128
E32.8 Other diseases of thymus
0.000 0.872 0.128
E32.1 Abscess of thymus
0.000 0.872 0.128
E32.0 Persistent hyperplasia of thymus
0.000 0.872 0.128
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.872 0.128
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.872 0.128
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.872 0.128
E61.9 Deficiency of nutrient element, unspecified
0.000 0.872 0.128
E61.8 Deficiency of other specified nutrient elements
0.000 0.872 0.128
E61.7 Deficiency of multiple nutrient elements
0.000 0.872 0.128
E61.6 Vanadium deficiency
0.000 0.872 0.128
E61.5 Molybdenum deficiency
0.000 0.872 0.128
E61.4 Chromium deficiency
0.000 0.872 0.128
E61.3 Manganese deficiency
0.000 0.872 0.128
E61.0 Copper deficiency
0.000 0.872 0.128
L27 Dermatitis due to substances taken internally
0.000 0.873 0.127
L30.3 Infective dermatitis
0.000 0.874 0.126
E53.8 Deficiency of other specified B group vitamins
0.000 0.875 0.125
E28 Ovarian dysfunction
0.000 0.876 0.124
L29.2 Pruritus vulvae
0.000 0.876 0.124
E22.1 Hyperprolactinaemia
0.000 0.878 0.122
L43 Lichen planus
0.088 0.879 0.033
E61.2 Magnesium deficiency
0.000 0.880 0.120
L29.8 Other pruritus
0.000 0.882 0.118
L23 Allergic contact dermatitis
0.000 0.882 0.117
L20.9 Atopic dermatitis, unspecified
0.000 0.884 0.116
L24 Irritant contact dermatitis
0.000 0.886 0.114
L26 Exfoliative dermatitis
0.000 0.886 0.114
L22 Diaper [napkin] dermatitis
0.000 0.886 0.114
E67 Other hyperalimentation
0.000 0.887 0.113
E68 Sequelae of hyperalimentation
0.000 0.887 0.113
E13.3 With ophthalmic complications
0.000 0.889 0.111
L21 Seborrhoeic dermatitis
0.000 0.891 0.109
E14 Unspecified diabetes mellitus
0.000 0.892 0.108
E44.1 Mild protein-energy malnutrition
0.000 0.893 0.107
E44.0 Moderate protein-energy malnutrition
0.000 0.893 0.107
E26.8 Other hyperaldosteronism
0.000 0.896 0.104
E26.1 Secondary hyperaldosteronism
0.000 0.896 0.104
L29.1 Pruritus scroti
0.000 0.896 0.104
E24.8 Other Cushing's syndrome
0.000 0.896 0.104
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.896 0.104
E24.3 Ectopic ACTH syndrome
0.000 0.896 0.104
E24.2 Drug-induced Cushing's syndrome
0.000 0.896 0.104
E24.1 Nelson's syndrome
0.000 0.896 0.104
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.896 0.104
L28 Lichen simplex chronicus and prurigo
0.000 0.897 0.103
L25 Unspecified contact dermatitis
0.000 0.897 0.102
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.899 0.101
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.899 0.101
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.904 0.096
L20.8 Other atopic dermatitis
0.000 0.904 0.096
L20.0 Besnier's prurigo
0.000 0.904 0.096
L23.1 Allergic contact dermatitis due to adhesives
0.000 0.904 0.096
E65 Localised adiposity
0.000 0.904 0.096
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.905 0.095
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.905 0.095
E16.4 Abnormal secretion of gastrin
0.000 0.905 0.095
E16.3 Increased secretion of glucagon
0.000 0.905 0.095
E14.3 With ophthalmic complications
0.000 0.905 0.095
E26.9 Hyperaldosteronism, unspecified
0.000 0.905 0.094
E24.0 Pituitary-dependent Cushing's disease
0.000 0.907 0.093
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.909 0.091
L27.8 Dermatitis due to other substances taken internally
0.000 0.909 0.091
L27.2 Dermatitis due to ingested food
0.000 0.909 0.091
E28.9 Ovarian dysfunction, unspecified
0.000 0.911 0.089
E28.8 Other ovarian dysfunction
0.000 0.911 0.089
E28.1 Androgen excess
0.000 0.911 0.089
E28.0 Oestrogen excess
0.000 0.911 0.089
L29.3 Anogenital pruritus, unspecified
0.000 0.913 0.087
L43.3 Subacute (active) lichen planus
0.063 0.913 0.024
L43.2 Lichenoid drug reaction
0.063 0.913 0.024
L43.1 Bullous lichen planus
0.063 0.913 0.024
L43.0 Hypertrophic lichen planus
0.063 0.913 0.024
E24.9 Cushing's syndrome, unspecified
0.000 0.914 0.085
E16.1 Other hypoglycaemia
0.000 0.915 0.085
E26.0 Primary hyperaldosteronism
0.000 0.915 0.085
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.915 0.084
L23.8 Allergic contact dermatitis due to other agents
0.000 0.915 0.084
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.915 0.084
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.000 0.915 0.084
L23.4 Allergic contact dermatitis due to dyes
0.000 0.915 0.084
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.000 0.915 0.084
L23.2 Allergic contact dermatitis due to cosmetics
0.000 0.915 0.084
L23.0 Allergic contact dermatitis due to metals
0.000 0.915 0.084
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.916 0.084
E66 Obesity
0.000 0.917 0.082
E28.3 Primary ovarian failure
0.000 0.918 0.082
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.918 0.082
L24.8 Irritant contact dermatitis due to other agents
0.000 0.918 0.082
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.918 0.082
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.918 0.082
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.918 0.082
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.918 0.082
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.918 0.082
L24.2 Irritant contact dermatitis due to solvents
0.000 0.918 0.082
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.918 0.082
L24.0 Irritant contact dermatitis due to detergents
0.000 0.918 0.082
E67.8 Other specified hyperalimentation
0.000 0.919 0.081
E67.3 Hypervitaminosis D
0.000 0.919 0.081
E67.2 Megavitamin-B6 syndrome
0.000 0.919 0.081
E67.1 Hypercarotenaemia
0.000 0.919 0.081
E67.0 Hypervitaminosis A
0.000 0.919 0.081
E16.2 Hypoglycaemia, unspecified
0.000 0.919 0.081
E04.2 Non-toxic multinodular goitre
0.000 0.920 0.080
M05-M14 Inflammatory polyarthropathies
0.029 0.921 0.049
L28.1 Prurigo nodularis
0.000 0.921 0.078
L21.8 Other seborrhoeic dermatitis
0.000 0.921 0.078
L21.1 Seborrhoeic infantile dermatitis
0.000 0.921 0.078
L21.0 Seborrhoea capitis
0.000 0.921 0.078
E14.8 With unspecified complications
0.000 0.922 0.078
E14.7 With multiple complications
0.000 0.922 0.078
E14.6 With other specified complications
0.000 0.922 0.078
E14.2 Withrenal complications
0.000 0.922 0.078
E14.0 With coma
0.000 0.922 0.078
L43.8 Other lichen planus
0.051 0.923 0.026
L28.2 Other prurigo
0.000 0.926 0.074
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.926 0.074
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.926 0.073
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.926 0.073
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.926 0.073
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.926 0.073
L25.2 Unspecified contact dermatitis due to dyes
0.000 0.926 0.073
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.000 0.926 0.073
L25.0 Unspecified contact dermatitis due to cosmetics
0.000 0.926 0.073
L23.5 Allergic contact dermatitis due to other chemical products
0.000 0.927 0.073
E66.8 Other obesity
0.000 0.927 0.073
E21.4 Other specified disorders of parathyroid gland
0.000 0.927 0.072
M50.1 Cervical disk disorder with radiculopathy
0.072 0.928 0.000
E14.1 With ketoacidosis
0.000 0.930 0.070
E14.4 With neurological complications
0.000 0.930 0.069
L29.0 Pruritus ani
0.000 0.931 0.069
E23 Hypofunction and other disorders of pituitary gland
0.001 0.932 0.068
K52 Other non-infective gastro-enteritis and colitis
0.000 0.933 0.067
M50 Cervical disk disorders
0.066 0.934 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.934 0.066
E21.2 Other hyperparathyroidism
0.000 0.934 0.066
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.935 0.065
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.935 0.065
M50.3 Other cervical disk degeneration
0.065 0.935 0.000
E14.5 With peripheral circulatory complications
0.000 0.937 0.063
M05 Seropositive rheumatoid arthritis
0.017 0.937 0.045
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.938 0.062
E66.1 Drug-induced obesity
0.000 0.941 0.059
M07 Psoriatic and enteropathic arthropathies
0.035 0.943 0.022
M09 Juvenile arthritis in diseases classified elsewhere
0.021 0.943 0.036
M08 Juvenile arthritis
0.021 0.943 0.036
M14 Arthropathies in other diseases classified elsewhere
0.018 0.943 0.039
M12 Other specific arthropathies
0.021 0.944 0.036
L28.0 Lichen simplex chronicus
0.000 0.944 0.056
K50.1 Crohn's disease of large intestine
0.000 0.945 0.055
L50-L54 Urticaria and erythema
0.000 0.945 0.055
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.945 0.054
M50.0 Cervical disk disorder with myelopathy
0.054 0.946 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.946 0.054
E66.0 Obesity due to excess calories
0.000 0.946 0.053
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.053 0.947 0.000
M50.8 Other cervical disk disorders
0.053 0.947 0.000
L52 Erythema nodosum
0.000 0.947 0.052
E21.3 Hyperparathyroidism, unspecified
0.000 0.948 0.052
E28.2 Polycystic ovarian syndrome
0.000 0.950 0.050
M11 Other crystal arthropathies
0.022 0.950 0.028
M05.9 Seropositive rheumatoid arthritis, unspecified
0.007 0.950 0.043
M89.9 Disorder of bone, unspecified
0.050 0.950 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.951 0.049
E23.1 Drug-induced hypopituitarism
0.001 0.951 0.049
L50 Urticaria
0.000 0.954 0.046
M07.3 Other psoriatic arthropathies
0.043 0.954 0.003
E23.0 Hypopituitarism
0.000 0.955 0.045
M05.8 Other seropositive rheumatoid arthritis
0.013 0.955 0.033

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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