TreeWAS – Variant ID: rs9262498

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	0.001	0.999
E03 Other hypothyroidism	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E05.9 Thyrotoxicosis, unspecified	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.982	0.018	0.000
K90 Intestinal malabsorption	0.000	0.074	0.926
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.140	0.860
K90.9 Intestinal malabsorption, unspecified	0.000	0.154	0.846
E03.8 Other specified hypothyroidism	0.000	0.167	0.833
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.202	0.798
E06 Thyroiditis	0.000	0.245	0.755
E07 Other disorders of thyroid	0.000	0.262	0.738
L40.4 Guttate psoriasis	0.720	0.280	0.000
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.716
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.706	0.294	0.000
K90.8 Other intestinal malabsorption	0.000	0.309	0.691
L40.3 Pustulosis palmaris et plantaris	0.676	0.324	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.336	0.664
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.336	0.664
K90.1 Tropical sprue	0.000	0.336	0.664
E03.1 Congenital hypothyroidism without goitre	0.000	0.353	0.647
L40.8 Other psoriasis	0.644	0.356	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.363	0.637
E06.9 Thyroiditis, unspecified	0.000	0.406	0.594
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.423	0.577
E07.8 Other specified disorders of thyroid	0.000	0.428	0.572
E06.3 Autoimmune thyroiditis	0.000	0.450	0.549
E06.5 Other chronic thyroiditis	0.000	0.459	0.541
E06.4 Drug-induced thyroiditis	0.000	0.459	0.541
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.459	0.541
E06.0 Acute thyroiditis	0.000	0.459	0.541
E07.1 Dyshormogenetic goitre	0.000	0.471	0.529
E07.0 Hypersecretion of calcitonin	0.000	0.471	0.529
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E06.1 Subacute thyroiditis	0.000	0.488	0.512
E07.9 Disorder of thyroid, unspecified	0.000	0.498	0.502
E05.8 Other thyrotoxicosis	0.001	0.510	0.490
E04 Other non-toxic goitre	0.000	0.546	0.454
E04.0 Non-toxic diffuse goitre	0.000	0.614	0.386
M07.39 Other psoriatic arthropathies (Site unspecified)	0.382	0.618	0.000
M07.3 Other psoriatic arthropathies	0.382	0.618	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.371	0.629	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.639	0.361
E53 Deficiency of other B group vitamins	0.000	0.645	0.355
E50-E64 Other nutritional deficiencies	0.000	0.646	0.354
E53.8 Deficiency of other specified B group vitamins	0.000	0.646	0.354
E04.2 Non-toxic multinodular goitre	0.000	0.649	0.351
L40-L45 Papulosquamous disorders	0.343	0.657	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.331	0.669	0.000
E04.8 Other specified non-toxic goitre	0.000	0.674	0.326
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.325	0.675	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.682	0.318
E20-E35 Disorders of other endocrine glands	0.000	0.682	0.318
E27 Other disorders of adrenal gland	0.000	0.687	0.313
M07.31 Other psoriatic arthropathies (Shoulder region)	0.309	0.691	0.000
M07.38 Other psoriatic arthropathies (Other)	0.306	0.694	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.695	0.305
M07.36 Other psoriatic arthropathies (Lower leg)	0.284	0.716	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.278	0.722	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.274	0.726	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.274	0.726	0.000
E58 Dietary calcium deficiency	0.000	0.735	0.264
E29 Testicular dysfunction	0.000	0.739	0.261
E56 Other vitamin deficiencies	0.000	0.741	0.259
L42 Pityriasis rosea	0.257	0.743	0.000
E53.1 Pyridoxine deficiency	0.000	0.745	0.255
E53.0 Riboflavin deficiency	0.000	0.745	0.255
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.746	0.254
E63 Other nutritional deficiencies	0.000	0.746	0.254
E50 Vitamin A deficiency	0.000	0.746	0.254
E60 Dietary zinc deficiency	0.000	0.746	0.254
E59 Dietary selenium deficiency	0.000	0.746	0.254
E54 Ascorbic acid deficiency	0.000	0.746	0.254
E52 Niacin deficiency [pellagra]	0.000	0.746	0.254
E22 Hyperfunction of pituitary gland	0.000	0.747	0.253
E20 Hypoparathyroidism	0.000	0.747	0.253
E51 Thiamine deficiency	0.000	0.748	0.252
L44 Other papulosquamous disorders	0.246	0.753	0.000
L41 Parapsoriasis	0.246	0.754	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.246	0.754	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.760	0.240
E27.2 Addisonian crisis	0.000	0.761	0.239
E40-E46 Malnutrition	0.000	0.765	0.235
E31 Polyglandular dysfunction	0.000	0.768	0.232
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.772	0.228
E32 Diseases of thymus	0.000	0.772	0.228
E30 Disorders of puberty, not elsewhere classified	0.000	0.772	0.228
E61 Deficiency of other nutrient elements	0.000	0.773	0.227
E27.5 Adrenomedullary hyperfunction	0.000	0.775	0.225
E27.0 Other adrenocortical overactivity	0.000	0.775	0.225
E26 Hyperaldosteronism	0.000	0.776	0.224
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.778	0.222
E28 Ovarian dysfunction	0.000	0.779	0.221
E22.1 Hyperprolactinaemia	0.000	0.780	0.220
E29.1 Testicular hypofunction	0.000	0.780	0.220
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.781	0.219
E20.9 Hypoparathyroidism, unspecified	0.000	0.782	0.218
E22.0 Acromegaly and pituitary gigantism	0.000	0.793	0.207
E25 Adrenogenital disorders	0.000	0.796	0.204
L43 Lichen planus	0.193	0.807	0.000
E56.1 Deficiency of vitamin K	0.000	0.809	0.191
E29.9 Testicular dysfunction, unspecified	0.000	0.813	0.187
E29.8 Other testicular dysfunction	0.000	0.813	0.187
E29.0 Testicular hyperfunction	0.000	0.813	0.187
E28.3 Primary ovarian failure	0.000	0.813	0.187
E56.9 Vitamin deficiency, unspecified	0.000	0.814	0.186
E56.8 Deficiency of other vitamins	0.000	0.814	0.186
E56.0 Deficiency of vitamin E	0.000	0.814	0.186
E23 Hypofunction and other disorders of pituitary gland	0.000	0.815	0.185
E50.9 Vitamin A deficiency, unspecified	0.000	0.817	0.182
E50.8 Other manifestations of vitamin A deficiency	0.000	0.817	0.182
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.817	0.182
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.817	0.182
E50.5 Vitamin A deficiency with night blindness	0.000	0.817	0.182
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.817	0.182
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.817	0.182
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.817	0.182
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.817	0.182
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.817	0.182
E63.9 Nutritional deficiency, unspecified	0.000	0.817	0.182
E63.8 Other specified nutritional deficiencies	0.000	0.817	0.182
E63.1 Imbalance of constituents of food intake	0.000	0.817	0.182
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.817	0.182
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.817	0.182
E64.8 Sequelae of other nutritional deficiencies	0.000	0.817	0.182
E64.3 Sequelae of rickets	0.000	0.817	0.182
E64.2 Sequelae of vitamin C deficiency	0.000	0.817	0.182
E64.1 Sequelae of vitamin A deficiency	0.000	0.817	0.182
E64.0 Sequelae of protein-energy malnutrition	0.000	0.817	0.182
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.818	0.182
E22.8 Other hyperfunction of pituitary gland	0.000	0.818	0.182
E20.8 Other hypoparathyroidism	0.000	0.818	0.181
E20.0 Idiopathic hypoparathyroidism	0.000	0.818	0.181
E51.9 Thiamine deficiency, unspecified	0.000	0.819	0.181
E51.8 Other manifestations of thiamine deficiency	0.000	0.819	0.181
E51.1 Beriberi	0.000	0.819	0.181
E51.2 Wernicke's encephalopathy	0.000	0.821	0.179
L44.0 Pityriasis rubra pilaris	0.177	0.823	0.000
L44.9 Papulosquamous disorder, unspecified	0.177	0.823	0.000
L44.8 Other specified papulosquamous disorders	0.177	0.823	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.177	0.823	0.000
L44.3 Lichen ruber moniliformis	0.177	0.823	0.000
L44.2 Lichen striatus	0.177	0.823	0.000
L44.1 Lichen nitidus	0.177	0.823	0.000
E24 Cushing's syndrome	0.000	0.823	0.177
L41.9 Parapsoriasis, unspecified	0.177	0.823	0.000
L41.8 Other parapsoriasis	0.177	0.823	0.000
L41.5 Retiform parapsoriasis	0.177	0.823	0.000
L41.4 Large plaque parapsoriasis	0.177	0.823	0.000
L41.3 Small plaque parapsoriasis	0.177	0.823	0.000
L41.2 Lymphomatoid papulosis	0.177	0.823	0.000
L41.1 Pityriasis lichenoides chronica	0.177	0.823	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.177	0.823	0.000
E55 Vitamin D deficiency	0.000	0.825	0.175
E31.0 Autoimmune polyglandular failure	0.000	0.829	0.171
E61.2 Magnesium deficiency	0.000	0.830	0.169
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.831	0.169
E45 Retarded development following protein-energy malnutrition	0.000	0.831	0.169
E43 Unspecified severe protein-energy malnutrition	0.000	0.831	0.169
E42 Marasmic kwashiorkor	0.000	0.831	0.169
E41 Nutritional marasmus	0.000	0.831	0.169
E40 Kwashiorkor	0.000	0.831	0.169
E31.9 Polyglandular dysfunction, unspecified	0.000	0.833	0.167
E31.8 Other polyglandular dysfunction	0.000	0.833	0.167
E31.1 Polyglandular hyperfunction	0.000	0.833	0.167
E30.9 Disorder of puberty, unspecified	0.000	0.836	0.164
E30.8 Other disorders of puberty	0.000	0.836	0.164
E30.1 Precocious puberty	0.000	0.836	0.164
E30.0 Delayed puberty	0.000	0.836	0.164
E32.9 Disease of thymus, unspecified	0.000	0.836	0.164
E32.8 Other diseases of thymus	0.000	0.836	0.164
E32.1 Abscess of thymus	0.000	0.836	0.164
E32.0 Persistent hyperplasia of thymus	0.000	0.836	0.164
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.836	0.164
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.836	0.164
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.836	0.164
E61.9 Deficiency of nutrient element, unspecified	0.000	0.837	0.163
E61.8 Deficiency of other specified nutrient elements	0.000	0.837	0.163
E61.7 Deficiency of multiple nutrient elements	0.000	0.837	0.163
E61.6 Vanadium deficiency	0.000	0.837	0.163
E61.5 Molybdenum deficiency	0.000	0.837	0.163
E61.4 Chromium deficiency	0.000	0.837	0.163
E61.3 Manganese deficiency	0.000	0.837	0.163
E61.0 Copper deficiency	0.000	0.837	0.163
M07 Psoriatic and enteropathic arthropathies	0.163	0.837	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.839	0.160
E26.8 Other hyperaldosteronism	0.000	0.839	0.160
E26.1 Secondary hyperaldosteronism	0.000	0.839	0.160
E28.9 Ovarian dysfunction, unspecified	0.000	0.841	0.159
E28.8 Other ovarian dysfunction	0.000	0.841	0.159
E28.1 Androgen excess	0.000	0.841	0.159
E28.0 Oestrogen excess	0.000	0.841	0.159
E20.1 Pseudohypoparathyroidism	0.000	0.841	0.158
E15 Nondiabetic hypoglycaemic coma	0.000	0.843	0.157
E34 Other endocrine disorders	0.000	0.843	0.157
E26.0 Primary hyperaldosteronism	0.000	0.844	0.156
E27.9 Disorder of adrenal gland, unspecified	0.000	0.848	0.152
E65-E68 Obesity and other hyperalimentation	0.000	0.848	0.152
E04.9 Non-toxic goitre, unspecified	0.000	0.849	0.151
K90-K93 Other diseases of the digestive system	0.000	0.852	0.148
E25.9 Adrenogenital disorder, unspecified	0.000	0.854	0.146
E25.8 Other adrenogenital disorders	0.000	0.854	0.146
E46 Unspecified protein-energy malnutrition	0.000	0.855	0.145
L43.8 Other lichen planus	0.145	0.855	0.000
E23.2 Diabetes insipidus	0.000	0.860	0.140
L43.3 Subacute (active) lichen planus	0.138	0.862	0.000
L43.2 Lichenoid drug reaction	0.138	0.862	0.000
L43.1 Bullous lichen planus	0.138	0.862	0.000
L43.0 Hypertrophic lichen planus	0.138	0.862	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.866	0.134
E23.7 Disorder of pituitary gland, unspecified	0.000	0.867	0.133
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.867	0.133
E23.1 Drug-induced hypopituitarism	0.000	0.867	0.133
G35 Multiple sclerosis	0.000	0.868	0.132
E27.8 Other specified disorders of adrenal gland	0.000	0.868	0.131
E24.8 Other Cushing's syndrome	0.000	0.873	0.127
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.873	0.127
E24.3 Ectopic ACTH syndrome	0.000	0.873	0.127
E24.1 Nelson's syndrome	0.000	0.873	0.127
E55.0 Rickets, active	0.000	0.874	0.126
E61.1 Iron deficiency	0.000	0.874	0.126
E24.0 Pituitary-dependent Cushing's disease	0.000	0.878	0.122
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.878	0.122
E44.1 Mild protein-energy malnutrition	0.000	0.879	0.121
E44.0 Moderate protein-energy malnutrition	0.000	0.879	0.121
E16 Other disorders of pancreatic internal secretion	0.000	0.883	0.117
M07.6 Other enteropathic arthropathies	0.117	0.883	0.000
M07.5 Arthropathy in ulcerative colitis	0.117	0.883	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.117	0.883	0.000
M07.2 Psoriatic spondylitis	0.117	0.883	0.000
M07.1 Arthritis mutilans	0.117	0.883	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.117	0.883	0.000
E23.6 Other disorders of pituitary gland	0.000	0.883	0.117
E34.5 Androgen resistance syndrome	0.000	0.887	0.113
E34.4 Constitutional tall stature	0.000	0.887	0.113
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.887	0.113
E34.1 Other hypersecretion of intestinal hormones	0.000	0.887	0.113
E67 Other hyperalimentation	0.000	0.891	0.109
E68 Sequelae of hyperalimentation	0.000	0.891	0.109
E34.3 Short stature, not elsewhere classified	0.000	0.892	0.108
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.894	0.106
E65 Localised adiposity	0.000	0.895	0.105
E34.0 Carcinoid syndrome	0.000	0.896	0.104
E34.8 Other specified endocrine disorders	0.000	0.897	0.102
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.898	0.102
E23.0 Hypopituitarism	0.000	0.901	0.099
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.901	0.099
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.904	0.096
E28.2 Polycystic ovarian syndrome	0.000	0.904	0.095
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.907	0.093
E34.9 Endocrine disorder, unspecified	0.000	0.914	0.086
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.914	0.086
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.916	0.084
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.916	0.084
E16.4 Abnormal secretion of gastrin	0.000	0.916	0.084
E16.3 Increased secretion of glucagon	0.000	0.916	0.084
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.084	0.916	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.084	0.916	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.084	0.916	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.084	0.916	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.084	0.916	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.084	0.916	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.084	0.916	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.084	0.916	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.084	0.916	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.084	0.916	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.084	0.916	0.000
M07.18 Arthritis mutilans (Other)	0.084	0.916	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.084	0.916	0.000
M07.16 Arthritis mutilans (Lower leg)	0.084	0.916	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.084	0.916	0.000
M07.14 Arthritis mutilans (Hand)	0.084	0.916	0.000
M07.13 Arthritis mutilans (Forearm)	0.084	0.916	0.000
M07.12 Arthritis mutilans (Upper arm)	0.084	0.916	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.084	0.916	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.084	0.916	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.084	0.916	0.000
M07.28 Psoriatic spondylitis (Other)	0.084	0.916	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.084	0.916	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.084	0.916	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.084	0.916	0.000
M07.24 Psoriatic spondylitis (Hand)	0.084	0.916	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.084	0.916	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.084	0.916	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.084	0.916	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.084	0.916	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.084	0.916	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.084	0.916	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.084	0.916	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.084	0.916	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.084	0.916	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.084	0.916	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.084	0.916	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.084	0.916	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.084	0.916	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.084	0.916	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.084	0.916	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.084	0.916	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.084	0.916	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.084	0.916	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.084	0.916	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.084	0.916	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.084	0.916	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.084	0.916	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.084	0.916	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.084	0.916	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.084	0.916	0.000
M07.68 Other enteropathic arthropathies (Other)	0.084	0.916	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.084	0.916	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.084	0.916	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.084	0.916	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.084	0.916	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.084	0.916	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.084	0.916	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.084	0.916	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.084	0.916	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.921	0.079
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.921	0.079
E67.8 Other specified hyperalimentation	0.000	0.921	0.078
E67.3 Hypervitaminosis D	0.000	0.921	0.078
E67.2 Megavitamin-B6 syndrome	0.000	0.921	0.078
E67.1 Hypercarotenaemia	0.000	0.921	0.078
E67.0 Hypervitaminosis A	0.000	0.921	0.078
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.922	0.078
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.923	0.077
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.924	0.076
K93.1 Megacolon in Chagas' disease	0.000	0.924	0.076
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.924	0.076
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.926	0.074
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.929	0.071
L43.9 Lichen planus, unspecified	0.071	0.929	0.000
E24.9 Cushing's syndrome, unspecified	0.001	0.930	0.070
G37 Other demyelinating diseases of central nervous system	0.000	0.934	0.065
K91.1 Postgastric surgery syndromes	0.000	0.935	0.065
E04.1 Non-toxic single thyroid nodule	0.000	0.935	0.065
E21.2 Other hyperparathyroidism	0.000	0.935	0.065
E16.1 Other hypoglycaemia	0.000	0.938	0.062
K91.5 Postcholecystectomy syndrome	0.000	0.940	0.060
E21.4 Other specified disorders of parathyroid gland	0.000	0.941	0.059
G36 Other acute disseminated demyelination	0.000	0.944	0.056
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.946	0.054
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.947	0.053
E16.2 Hypoglycaemia, unspecified	0.000	0.950	0.050
G37.5 Concentric sclerosis [Balo]	0.000	0.953	0.047
G37.4 Subacute necrotising myelitis	0.000	0.953	0.047
G37.2 Central pontine myelinolysis	0.000	0.953	0.047
G37.1 Central demyelination of corpus callosum	0.000	0.953	0.047
G37.0 Diffuse sclerosis	0.000	0.953	0.047
E55.9 Vitamin D deficiency, unspecified	0.000	0.953	0.047
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.954	0.046
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.958	0.041
E89.0 Postprocedural hypothyroidism	0.000	0.958	0.042
G36.0 Neuromyelitis optica [Devic]	0.000	0.959	0.041
G36.9 Acute disseminated demyelination, unspecified	0.000	0.960	0.040
G36.8 Other specified acute disseminated demyelination	0.000	0.960	0.040
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.960	0.040
E10-E14 Diabetes mellitus	0.000	0.963	0.037
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.965	0.035
E70-E90 Metabolic disorders	0.000	0.968	0.032
E21.3 Hyperparathyroidism, unspecified	0.000	0.970	0.030
Q61.2 Polycystic kidney, adult type	0.030	0.970	0.000
Q61 Cystic kidney disease	0.029	0.971	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.971	0.029
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.972	0.028
Q61.3 Polycystic kidney, unspecified	0.027	0.973	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.973	0.027
E89.4 Postprocedural ovarian failure	0.000	0.973	0.027
Q61.0 Congenital single renal cyst	0.026	0.974	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.974	0.026
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.974	0.026
E89.5 Postprocedural testicular hypofunction	0.000	0.974	0.026
E89.1 Postprocedural hypoinsulinaemia	0.000	0.974	0.026
E89.3 Postprocedural hypopituitarism	0.000	0.976	0.024
E73 Lactose intolerance	0.000	0.976	0.024
E77 Disorders of glycoprotein metabolism	0.000	0.977	0.023
E76 Disorders of glycosaminoglycan metabolism	0.000	0.977	0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.977	0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.977	0.023
E88 Other metabolic disorders	0.000	0.977	0.023
Q61.9 Cystic kidney disease, unspecified	0.023	0.977	0.000
E13 Other specified diabetes mellitus	0.000	0.977	0.022
E84 Cystic fibrosis	0.000	0.978	0.022
E79 Disorders of purine and pyrimidine metabolism	0.000	0.978	0.022
E70 Disorders of aromatic amino-acid metabolism	0.000	0.978	0.022
M79.65 Pain in limb (Pelvic region and thigh)	0.022	0.978	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.979	0.021
E72 Other disorders of amino-acid metabolism	0.000	0.979	0.021
Q61.4 Renal dysplasia	0.021	0.979	0.000
Q61.8 Other cystic kidney diseases	0.021	0.979	0.000
Q61.1 Polycystic kidney, infantile type	0.021	0.979	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.979	0.021
Q60-Q64 Congenital malformations of the urinary system	0.021	0.979	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.979	0.021
E14 Unspecified diabetes mellitus	0.000	0.980	0.020
C32.0 Glottis	0.020	0.980	0.000
E14.3 With ophthalmic complications	0.000	0.980	0.020
E12.9 Without complications	0.000	0.980	0.019
E12.8 With unspecified complications	0.000	0.980	0.019
E12.7 With multiple complications	0.000	0.980	0.019
E12.6 With other specified complications	0.000	0.980	0.019
E12.5 With peripheral circulatory complications	0.000	0.980	0.019
E12.4 With neurological complications	0.000	0.980	0.019
E12.3 With ophthalmic complications	0.000	0.980	0.019
E12.2 With renal complications	0.000	0.980	0.019
E12.1 With ketoacidosis	0.000	0.980	0.019
E12.0 With coma	0.000	0.980	0.019
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.981	0.019
E88.3 Tumour lysis syndrome	0.000	0.982	0.018
E74 Other disorders of carbohydrate metabolism	0.000	0.982	0.018
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.018	0.982	0.000
Q61.5 Medullary cystic kidney	0.018	0.982	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.982	0.018
E73.8 Other lactose intolerance	0.000	0.983	0.017
E73.1 Secondary lactase deficiency	0.000	0.983	0.017
E73.0 Congenital lactase deficiency	0.000	0.983	0.017
Q60 Renal agenesis and other reduction defects of kidney	0.017	0.983	0.000
E71.3 Disorders of fatty-acid metabolism	0.000	0.983	0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.983	0.017
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.983	0.017
E71.0 Maple-syrup-urine disease	0.000	0.983	0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.983	0.017
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.983	0.017
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.983	0.017
E76.2 Other mucopolysaccharidoses	0.000	0.983	0.017
E76.1 Mucopolysaccharidosis, type II	0.000	0.983	0.017
E76.0 Mucopolysaccharidosis, type I	0.000	0.983	0.017
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.983	0.017
E77.8 Other disorders of glycoprotein metabolism	0.000	0.983	0.017
E77.1 Defects in glycoprotein degradation	0.000	0.983	0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.983	0.017
E14.5 With peripheral circulatory complications	0.000	0.983	0.016
E13.8 With unspecified complications	0.000	0.984	0.016
E13.7 With multiple complications	0.000	0.984	0.016
E13.6 With other specified complications	0.000	0.984	0.016
E13.5 With peripheral circulatory complications	0.000	0.984	0.016
E13.4 With neurological complications	0.000	0.984	0.016
E13.3 With ophthalmic complications	0.000	0.984	0.016
E13.2 With renal complications	0.000	0.984	0.016
E13.1 With ketoacidosis	0.000	0.984	0.016
E13.0 With coma	0.000	0.984	0.016
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.984	0.016
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.984	0.016
E79.1 Lesch-Nyhan syndrome	0.000	0.984	0.016
E84.8 Cystic fibrosis with other manifestations	0.000	0.984	0.016
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.984	0.016
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.984	0.016
E80.1 Porphyria cutanea tarda	0.000	0.984	0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.984	0.016
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.984	0.016
E70.2 Disorders of tyrosine metabolism	0.000	0.984	0.016
E70.1 Other hyperphenylalaninaemias	0.000	0.984	0.016
E70.0 Classical phenylketonuria	0.000	0.984	0.016
E88.8 Other specified metabolic disorders	0.000	0.984	0.016
E66 Obesity	0.000	0.984	0.016
E88.9 Metabolic disorder, unspecified	0.000	0.984	0.015
E75.6 Lipid storage disorder, unspecified	0.000	0.984	0.015
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.984	0.015
E75.3 Sphingolipidosis, unspecified	0.000	0.984	0.015
E75.1 Other gangliosidosis	0.000	0.984	0.015
E75.0 GM2 gangliosidosis	0.000	0.984	0.015
E75.5 Other lipid storage disorders	0.000	0.984	0.015
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.985	0.015
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.015
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.985	0.015
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.985	0.015
E72.5 Disorders of glycine metabolism	0.000	0.985	0.015
E72.4 Disorders of ornithine metabolism	0.000	0.985	0.015
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.985	0.015
E72.2 Disorders of urea cycle metabolism	0.000	0.985	0.015
E72.0 Disorders of amino-acid transport	0.000	0.985	0.015
Q64 Other congenital malformations of urinary system	0.015	0.985	0.000
Q62.2 Congenital megaloureter	0.015	0.985	0.000
E70.3 Albinism	0.000	0.985	0.015
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.985	0.015
E80.5 Crigler-Najjar syndrome	0.000	0.985	0.015
E80.3 Defects of catalase and peroxydase	0.000	0.985	0.015
E80.0 Hereditary erythropoietic porphyria	0.000	0.985	0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations