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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9262615
log Bayes Factor = 55.7144
Chromosome 6   position 31,021,161  (GRCh37) Explore rs9262615 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.033 0.967
E10.3 With ophthalmic complications
0.000 0.034 0.966
E10.9 Without complications
0.000 0.075 0.925
E10.1 With ketoacidosis
0.000 0.085 0.915
E10-E14 Diabetes mellitus
0.000 0.153 0.847
E10.2 With renal complications
0.000 0.153 0.847
E16.2 Hypoglycaemia, unspecified
0.000 0.170 0.830
E16 Other disorders of pancreatic internal secretion
0.000 0.175 0.825
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.183 0.817
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.187 0.813
E10.0 With coma
0.000 0.206 0.794
R31 Unspecified haematuria
0.777 0.223 0.000
E10.6 With other specified complications
0.000 0.241 0.759
E10.5 With peripheral circulatory complications
0.000 0.247 0.753
E10.4 With neurological complications
0.000 0.259 0.741
E10.7 With multiple complications
0.000 0.306 0.694
E00-E07 Disorders of thyroid gland
0.079 0.322 0.599
E13 Other specified diabetes mellitus
0.000 0.331 0.668
E03 Other hypothyroidism
0.429 0.338 0.232
E10.8 With unspecified complications
0.000 0.351 0.648
E16.1 Other hypoglycaemia
0.000 0.352 0.648
K90 Intestinal malabsorption
0.000 0.357 0.643
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.358 0.642
E50-E64 Other nutritional deficiencies
0.000 0.367 0.633
E12 Malnutrition-related diabetes mellitus
0.000 0.392 0.608
E55 Vitamin D deficiency
0.000 0.399 0.601
E05 Thyrotoxicosis [hyperthyroidism]
0.007 0.403 0.589
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.409 0.591
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.409 0.591
E16.4 Abnormal secretion of gastrin
0.000 0.409 0.591
E16.3 Increased secretion of glucagon
0.000 0.409 0.591
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.413 0.587
E15 Nondiabetic hypoglycaemic coma
0.000 0.414 0.586
E55.9 Vitamin D deficiency, unspecified
0.000 0.422 0.578
E13.9 Without complications
0.000 0.443 0.557
K90.8 Other intestinal malabsorption
0.000 0.482 0.518
E70-E90 Metabolic disorders
0.000 0.483 0.517
E83.1 Disorders of iron metabolism
0.000 0.487 0.513
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.495 0.505
E83 Disorders of mineral metabolism
0.000 0.496 0.504
K90.9 Intestinal malabsorption, unspecified
0.000 0.504 0.496
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.057 0.514 0.429
E00 Congenital iodine-deficiency syndrome
0.057 0.514 0.429
M45.X9 Ankylosing spondylitis (Site unspecified)
0.485 0.515 0.000
E88 Other metabolic disorders
0.000 0.519 0.480
E13.8 With unspecified complications
0.000 0.521 0.479
E13.7 With multiple complications
0.000 0.521 0.479
E13.6 With other specified complications
0.000 0.521 0.479
E13.5 With peripheral circulatory complications
0.000 0.521 0.479
E13.4 With neurological complications
0.000 0.521 0.479
E13.2 With renal complications
0.000 0.521 0.479
E13.1 With ketoacidosis
0.000 0.521 0.479
E13.0 With coma
0.000 0.521 0.479
E02 Subclinical iodine-deficiency hypothyroidism
0.055 0.523 0.422
E03.5 Myxoedema coma
0.308 0.526 0.166
E03.4 Atrophy of thyroid (acquired)
0.308 0.526 0.166
E03.3 Postinfectious hypothyroidism
0.308 0.526 0.166
E03.1 Congenital hypothyroidism without goitre
0.308 0.526 0.166
E03.0 Congenital hypothyroidism with diffuse goitre
0.308 0.526 0.166
K90.3 Pancreatic steatorrhoea
0.000 0.539 0.461
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.539 0.461
K90.1 Tropical sprue
0.000 0.539 0.461
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.298 0.546 0.156
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.546 0.454
E63 Other nutritional deficiencies
0.000 0.546 0.454
E51 Thiamine deficiency
0.000 0.546 0.454
E50 Vitamin A deficiency
0.000 0.546 0.454
E60 Dietary zinc deficiency
0.000 0.546 0.454
E59 Dietary selenium deficiency
0.000 0.546 0.454
E54 Ascorbic acid deficiency
0.000 0.546 0.454
E52 Niacin deficiency [pellagra]
0.000 0.546 0.454
E85 Amyloidosis
0.000 0.546 0.454
E40-E46 Malnutrition
0.000 0.546 0.453
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.549 0.451
E13.3 With ophthalmic complications
0.000 0.549 0.451
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.004 0.551 0.446
E05.8 Other thyrotoxicosis
0.005 0.551 0.444
E12.9 Without complications
0.000 0.564 0.436
E12.8 With unspecified complications
0.000 0.564 0.436
E12.7 With multiple complications
0.000 0.564 0.436
E12.6 With other specified complications
0.000 0.564 0.436
E12.5 With peripheral circulatory complications
0.000 0.564 0.436
E12.4 With neurological complications
0.000 0.564 0.436
E12.3 With ophthalmic complications
0.000 0.564 0.436
E12.2 With renal complications
0.000 0.564 0.436
E12.1 With ketoacidosis
0.000 0.564 0.436
E12.0 With coma
0.000 0.564 0.436
E58 Dietary calcium deficiency
0.000 0.567 0.433
E55.0 Rickets, active
0.000 0.569 0.431
E03.8 Other specified hypothyroidism
0.277 0.570 0.153
M45 Ankylosing spondylitis
0.430 0.570 0.000
E05.5 Thyroid crisis or storm
0.005 0.572 0.423
E05.4 Thyrotoxicosis factitia
0.005 0.572 0.423
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.005 0.572 0.423
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.005 0.572 0.423
E14 Unspecified diabetes mellitus
0.000 0.579 0.421
E56 Other vitamin deficiencies
0.000 0.595 0.405
E11 Non-insulin-dependent diabetes mellitus
0.000 0.598 0.402
E07 Other disorders of thyroid
0.075 0.615 0.310
E65-E68 Obesity and other hyperalimentation
0.000 0.620 0.380
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.380 0.620 0.000
E83.5 Disorders of calcium metabolism
0.000 0.620 0.380
E88.2 Lipomatosis, not elsewhere classified
0.000 0.621 0.379
E74 Other disorders of carbohydrate metabolism
0.000 0.626 0.374
E85.3 Secondary systemic amyloidosis
0.000 0.627 0.373
E11.4 With neurological complications
0.000 0.628 0.372
E79 Disorders of purine and pyrimidine metabolism
0.000 0.629 0.370
E77 Disorders of glycoprotein metabolism
0.000 0.629 0.370
E76 Disorders of glycosaminoglycan metabolism
0.000 0.629 0.370
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.629 0.370
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.629 0.370
E85.9 Amyloidosis, unspecified
0.000 0.636 0.364
E84 Cystic fibrosis
0.000 0.637 0.363
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.638 0.362
E83.8 Other disorders of mineral metabolism
0.000 0.638 0.362
E83.2 Disorders of zinc metabolism
0.000 0.638 0.362
E83.0 Disorders of copper metabolism
0.000 0.638 0.362
M45.X2 Ankylosing spondylitis (Cervical region)
0.360 0.640 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.360 0.640 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.644 0.356
E73 Lactose intolerance
0.000 0.649 0.351
E72 Other disorders of amino-acid metabolism
0.000 0.649 0.350
E06 Thyroiditis
0.052 0.650 0.299
E85.4 Organ-limited amyloidosis
0.000 0.650 0.350
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.041 0.651 0.308
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.041 0.651 0.308
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.041 0.651 0.308
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.041 0.651 0.308
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.041 0.651 0.308
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.041 0.651 0.308
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.041 0.651 0.308
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.041 0.651 0.308
E53 Deficiency of other B group vitamins
0.000 0.652 0.348
E88.9 Metabolic disorder, unspecified
0.000 0.655 0.345
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.659 0.341
E88.3 Tumour lysis syndrome
0.000 0.665 0.335
E88.8 Other specified metabolic disorders
0.000 0.665 0.334
E14.1 With ketoacidosis
0.000 0.668 0.332
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.671 0.329
E11.8 With unspecified complications
0.000 0.673 0.327
E50.9 Vitamin A deficiency, unspecified
0.000 0.674 0.325
E50.8 Other manifestations of vitamin A deficiency
0.000 0.674 0.325
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.674 0.325
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.674 0.325
E50.5 Vitamin A deficiency with night blindness
0.000 0.674 0.325
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.674 0.325
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.674 0.325
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.674 0.325
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.674 0.325
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.674 0.325
E51.9 Thiamine deficiency, unspecified
0.000 0.674 0.325
E51.8 Other manifestations of thiamine deficiency
0.000 0.674 0.325
E51.2 Wernicke's encephalopathy
0.000 0.674 0.325
E51.1 Beriberi
0.000 0.674 0.325
E63.9 Nutritional deficiency, unspecified
0.000 0.674 0.325
E63.8 Other specified nutritional deficiencies
0.000 0.674 0.325
E63.1 Imbalance of constituents of food intake
0.000 0.674 0.325
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.674 0.325
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.674 0.325
E64.8 Sequelae of other nutritional deficiencies
0.000 0.674 0.325
E64.3 Sequelae of rickets
0.000 0.674 0.325
E64.2 Sequelae of vitamin C deficiency
0.000 0.674 0.325
E64.1 Sequelae of vitamin A deficiency
0.000 0.674 0.325
E64.0 Sequelae of protein-energy malnutrition
0.000 0.674 0.325
E85.8 Other amyloidosis
0.000 0.675 0.325
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.675 0.325
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.675 0.325
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.675 0.325
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.675 0.325
E45 Retarded development following protein-energy malnutrition
0.000 0.675 0.325
E43 Unspecified severe protein-energy malnutrition
0.000 0.675 0.325
E42 Marasmic kwashiorkor
0.000 0.675 0.325
E41 Nutritional marasmus
0.000 0.675 0.325
E40 Kwashiorkor
0.000 0.675 0.325
E61 Deficiency of other nutrient elements
0.000 0.680 0.320
E14.8 With unspecified complications
0.000 0.685 0.315
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.308 0.692 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.308 0.692 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.308 0.692 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.308 0.692 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.308 0.692 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.308 0.692 0.000
E14.4 With neurological complications
0.000 0.694 0.306
E14.7 With multiple complications
0.000 0.698 0.302
E14.2 Withrenal complications
0.000 0.698 0.302
E14.0 With coma
0.000 0.698 0.302
E20-E35 Disorders of other endocrine glands
0.000 0.701 0.299
E14.3 With ophthalmic complications
0.000 0.704 0.296
E14.6 With other specified complications
0.000 0.707 0.293
E56.9 Vitamin deficiency, unspecified
0.000 0.709 0.290
E56.8 Deficiency of other vitamins
0.000 0.709 0.290
E56.0 Deficiency of vitamin E
0.000 0.709 0.290
E11.7 With multiple complications
0.000 0.712 0.288
E07.8 Other specified disorders of thyroid
0.040 0.714 0.246
E86 Volume depletion
0.000 0.715 0.285
E11.1 With ketoacidosis
0.000 0.718 0.282
E07.1 Dyshormogenetic goitre
0.054 0.724 0.222
E07.0 Hypersecretion of calcitonin
0.054 0.724 0.222
E11.5 With peripheral circulatory complications
0.000 0.727 0.273
E67 Other hyperalimentation
0.000 0.727 0.273
E68 Sequelae of hyperalimentation
0.000 0.727 0.273
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.728 0.272
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.731 0.268
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.731 0.268
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.731 0.268
E74.2 Disorders of galactose metabolism
0.000 0.731 0.268
E74.1 Disorders of fructose metabolism
0.000 0.731 0.268
E74.0 Glycogen storage disease
0.000 0.731 0.268
E71.3 Disorders of fatty-acid metabolism
0.000 0.734 0.266
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.734 0.266
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.734 0.266
E71.0 Maple-syrup-urine disease
0.000 0.734 0.266
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.734 0.266
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.734 0.266
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.734 0.266
E76.2 Other mucopolysaccharidoses
0.000 0.734 0.266
E76.1 Mucopolysaccharidosis, type II
0.000 0.734 0.266
E76.0 Mucopolysaccharidosis, type I
0.000 0.734 0.266
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.734 0.266
E77.8 Other disorders of glycoprotein metabolism
0.000 0.734 0.266
E77.1 Defects in glycoprotein degradation
0.000 0.734 0.266
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.734 0.266
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.734 0.266
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.734 0.266
E79.1 Lesch-Nyhan syndrome
0.000 0.734 0.266
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.734 0.266
E11.6 With other specified complications
0.000 0.737 0.263
E84.8 Cystic fibrosis with other manifestations
0.000 0.739 0.261
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.739 0.261
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.739 0.261
E11.2 With renal complications
0.000 0.745 0.255
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.745 0.255
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.745 0.255
E70.2 Disorders of tyrosine metabolism
0.000 0.745 0.255
E70.1 Other hyperphenylalaninaemias
0.000 0.745 0.255
E70.0 Classical phenylketonuria
0.000 0.745 0.255
E06.9 Thyroiditis, unspecified
0.030 0.746 0.224
E14.5 With peripheral circulatory complications
0.000 0.746 0.254
E84.9 Cystic fibrosis, unspecified
0.000 0.746 0.253
E27 Other disorders of adrenal gland
0.000 0.747 0.253
E73.8 Other lactose intolerance
0.000 0.748 0.251
E73.1 Secondary lactase deficiency
0.000 0.748 0.251
E73.0 Congenital lactase deficiency
0.000 0.748 0.251
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.748 0.251
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.748 0.251
E72.5 Disorders of glycine metabolism
0.000 0.748 0.251
E72.4 Disorders of ornithine metabolism
0.000 0.748 0.251
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.748 0.251
E72.2 Disorders of urea cycle metabolism
0.000 0.748 0.251
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.748 0.251
E06.4 Drug-induced thyroiditis
0.037 0.749 0.214
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.037 0.749 0.214
E06.0 Acute thyroiditis
0.037 0.749 0.214
E53.9 Vitamin B deficiency, unspecified
0.000 0.749 0.251
E53.1 Pyridoxine deficiency
0.000 0.750 0.249
E53.0 Riboflavin deficiency
0.000 0.750 0.249
E20 Hypoparathyroidism
0.000 0.757 0.243
E56.1 Deficiency of vitamin K
0.001 0.758 0.241
E70.3 Albinism
0.000 0.760 0.240
E05.9 Thyrotoxicosis, unspecified
0.001 0.760 0.240
E06.1 Subacute thyroiditis
0.038 0.760 0.202
E75.6 Lipid storage disorder, unspecified
0.000 0.764 0.236
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.764 0.236
E75.3 Sphingolipidosis, unspecified
0.000 0.764 0.236
E75.2 Other sphingolipidosis
0.000 0.764 0.236
E75.1 Other gangliosidosis
0.000 0.764 0.236
E75.0 GM2 gangliosidosis
0.000 0.764 0.236
E11.3 With ophthalmic complications
0.000 0.764 0.236
E27.1 Primary adrenocortical insufficiency
0.000 0.764 0.236
E44.1 Mild protein-energy malnutrition
0.000 0.767 0.233
E44.0 Moderate protein-energy malnutrition
0.000 0.767 0.233
E73.9 Lactose intolerance, unspecified
0.000 0.768 0.232
E72.0 Disorders of amino-acid transport
0.000 0.768 0.231
E61.9 Deficiency of nutrient element, unspecified
0.000 0.770 0.230
E61.8 Deficiency of other specified nutrient elements
0.000 0.770 0.230
E61.7 Deficiency of multiple nutrient elements
0.000 0.770 0.230
E61.6 Vanadium deficiency
0.000 0.770 0.230
E61.5 Molybdenum deficiency
0.000 0.770 0.230
E61.4 Chromium deficiency
0.000 0.770 0.230
E61.3 Manganese deficiency
0.000 0.770 0.230
E61.0 Copper deficiency
0.000 0.770 0.230
E65 Localised adiposity
0.000 0.771 0.229
E29 Testicular dysfunction
0.000 0.774 0.226
E22 Hyperfunction of pituitary gland
0.000 0.776 0.224
E06.5 Other chronic thyroiditis
0.042 0.781 0.177
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.781 0.218
E11.0 With coma
0.000 0.782 0.217
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.785 0.215
E32 Diseases of thymus
0.000 0.785 0.215
E31 Polyglandular dysfunction
0.000 0.785 0.215
E30 Disorders of puberty, not elsewhere classified
0.000 0.785 0.215
E25 Adrenogenital disorders
0.000 0.786 0.214
E24 Cushing's syndrome
0.000 0.796 0.204
E20.9 Hypoparathyroidism, unspecified
0.000 0.797 0.202
E61.2 Magnesium deficiency
0.000 0.799 0.201
E46 Unspecified protein-energy malnutrition
0.000 0.804 0.195
E67.8 Other specified hyperalimentation
0.000 0.804 0.196
E67.3 Hypervitaminosis D
0.000 0.804 0.196
E67.2 Megavitamin-B6 syndrome
0.000 0.804 0.196
E67.1 Hypercarotenaemia
0.000 0.804 0.196
E67.0 Hypervitaminosis A
0.000 0.804 0.196
E75.5 Other lipid storage disorders
0.000 0.805 0.195
E23 Hypofunction and other disorders of pituitary gland
0.000 0.809 0.191
E34 Other endocrine disorders
0.000 0.809 0.191
E22.1 Hyperprolactinaemia
0.000 0.811 0.189
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.817 0.183
E06.3 Autoimmune thyroiditis
0.031 0.818 0.151
E27.5 Adrenomedullary hyperfunction
0.000 0.818 0.182
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.818 0.182
E27.0 Other adrenocortical overactivity
0.000 0.818 0.182
E20.8 Other hypoparathyroidism
0.000 0.826 0.174
E20.1 Pseudohypoparathyroidism
0.000 0.826 0.174
E20.0 Idiopathic hypoparathyroidism
0.000 0.826 0.174
E29.1 Testicular hypofunction
0.000 0.826 0.174
E27.8 Other specified disorders of adrenal gland
0.000 0.830 0.170
E27.9 Disorder of adrenal gland, unspecified
0.000 0.830 0.170
E23.6 Other disorders of pituitary gland
0.000 0.834 0.166
E04 Other non-toxic goitre
0.024 0.835 0.141
E29.9 Testicular dysfunction, unspecified
0.000 0.837 0.162
E29.8 Other testicular dysfunction
0.000 0.837 0.162
E29.0 Testicular hyperfunction
0.000 0.837 0.162
E34.0 Carcinoid syndrome
0.000 0.838 0.162
E80.2 Other porphyria
0.000 0.838 0.162
E22.0 Acromegaly and pituitary gigantism
0.000 0.839 0.161
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.839 0.161
E22.8 Other hyperfunction of pituitary gland
0.000 0.839 0.161
E66 Obesity
0.000 0.841 0.159
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.843 0.157
E80.5 Crigler-Najjar syndrome
0.000 0.843 0.157
E80.3 Defects of catalase and peroxydase
0.000 0.843 0.157
E80.1 Porphyria cutanea tarda
0.000 0.843 0.157
E80.0 Hereditary erythropoietic porphyria
0.000 0.843 0.157
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.843 0.157
E30.9 Disorder of puberty, unspecified
0.000 0.846 0.154
E30.8 Other disorders of puberty
0.000 0.846 0.154
E30.1 Precocious puberty
0.000 0.846 0.154
E30.0 Delayed puberty
0.000 0.846 0.154
E31.9 Polyglandular dysfunction, unspecified
0.000 0.846 0.154
E31.8 Other polyglandular dysfunction
0.000 0.846 0.154
E31.1 Polyglandular hyperfunction
0.000 0.846 0.154
E31.0 Autoimmune polyglandular failure
0.000 0.846 0.154
E32.9 Disease of thymus, unspecified
0.000 0.846 0.154
E32.8 Other diseases of thymus
0.000 0.846 0.154
E32.1 Abscess of thymus
0.000 0.846 0.154
E32.0 Persistent hyperplasia of thymus
0.000 0.846 0.154
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.846 0.154
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.846 0.154
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.846 0.154
E25.9 Adrenogenital disorder, unspecified
0.000 0.846 0.153
E25.8 Other adrenogenital disorders
0.000 0.846 0.153
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.847 0.153
E27.2 Addisonian crisis
0.000 0.848 0.152
E61.1 Iron deficiency
0.000 0.850 0.150
E24.8 Other Cushing's syndrome
0.000 0.853 0.147
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.853 0.147
E24.3 Ectopic ACTH syndrome
0.000 0.853 0.147
E24.1 Nelson's syndrome
0.000 0.853 0.147
E24.0 Pituitary-dependent Cushing's disease
0.000 0.853 0.147
E24.9 Cushing's syndrome, unspecified
0.000 0.855 0.145
E26 Hyperaldosteronism
0.000 0.855 0.145
E53.8 Deficiency of other specified B group vitamins
0.000 0.860 0.140
E80.6 Other disorders of bilirubin metabolism
0.000 0.862 0.138
E24.2 Drug-induced Cushing's syndrome
0.000 0.862 0.138
E83.3 Disorders of phosphorus metabolism
0.001 0.862 0.137
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.863 0.137
E23.1 Drug-induced hypopituitarism
0.000 0.863 0.137
E34.5 Androgen resistance syndrome
0.000 0.863 0.137
E34.4 Constitutional tall stature
0.000 0.863 0.137
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.863 0.137
E34.1 Other hypersecretion of intestinal hormones
0.000 0.863 0.137
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.864 0.136
E66.0 Obesity due to excess calories
0.000 0.871 0.129
M45-M49 Spondylopathies
0.129 0.871 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.873 0.126
M46 Other inflammatory spondylopathies
0.124 0.876 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.879 0.121
E34.9 Endocrine disorder, unspecified
0.000 0.879 0.121
E23.7 Disorder of pituitary gland, unspecified
0.000 0.880 0.120
E23.0 Hypopituitarism
0.000 0.880 0.120
E04.8 Other specified non-toxic goitre
0.017 0.882 0.101
M46.9 Inflammatory spondylopathy, unspecified
0.118 0.882 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.118 0.882 0.000
E34.8 Other specified endocrine disorders
0.000 0.882 0.118
E14.9 Without complications
0.000 0.884 0.116
E04.0 Non-toxic diffuse goitre
0.015 0.884 0.101
E66.1 Drug-induced obesity
0.000 0.886 0.114
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.887 0.113
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.887 0.113
E89.5 Postprocedural testicular hypofunction
0.000 0.887 0.113
G93 Other disorders of brain
0.112 0.888 0.000
G90-G99 Other disorders of the nervous system
0.111 0.889 0.000
G93.2 Benign intracranial hypertension
0.110 0.890 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.890 0.110
G91 Hydrocephalus
0.110 0.890 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.891 0.108
G93.8 Other specified disorders of brain
0.106 0.894 0.000
E89.1 Postprocedural hypoinsulinaemia
0.000 0.894 0.106
E04.9 Non-toxic goitre, unspecified
0.004 0.894 0.102
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.895 0.105
G93.0 Cerebral cysts
0.105 0.895 0.000
E26.8 Other hyperaldosteronism
0.000 0.896 0.104
E26.1 Secondary hyperaldosteronism
0.000 0.896 0.104
G91.9 Hydrocephalus, unspecified
0.104 0.896 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.896 0.103
E07.9 Disorder of thyroid, unspecified
0.076 0.897 0.026
G90 Disorders of autonomic nervous system
0.100 0.900 0.000
E89.4 Postprocedural ovarian failure
0.000 0.900 0.100
E28 Ovarian dysfunction
0.001 0.901 0.098
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.902 0.098
E21.4 Other specified disorders of parathyroid gland
0.000 0.902 0.098
M46.2 Osteomyelitis of vertebra
0.097 0.903 0.000
G91.1 Obstructive hydrocephalus
0.097 0.903 0.000
G95 Other diseases of spinal cord
0.096 0.904 0.000
E21.2 Other hyperparathyroidism
0.000 0.904 0.096
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.905 0.095
M46.4 Discitis, unspecified
0.095 0.905 0.000
E23.2 Diabetes insipidus
0.000 0.906 0.094
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.090 0.910 0.000
G90.3 Multisystem degeneration
0.090 0.910 0.000
M46.8 Other specified inflammatory spondylopathies
0.089 0.911 0.000
M46.5 Other infective spondylopathies
0.089 0.911 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.089 0.911 0.000
M46.0 Spinal enthesopathy
0.089 0.911 0.000
G93.5 Compression of brain
0.088 0.912 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.088 0.912 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.912 0.088
G95.0 Syringomyelia and syringobulbia
0.088 0.912 0.000
G91.2 Normal-pressure hydrocephalus
0.086 0.914 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.085 0.915 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.085 0.915 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.085 0.915 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.085 0.915 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.085 0.915 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.082 0.917 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.082 0.918 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.082 0.918 0.000
G91.8 Other hydrocephalus
0.082 0.918 0.000
G95.8 Other specified diseases of spinal cord
0.082 0.918 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.081 0.919 0.000
G93.7 Reye's syndrome
0.081 0.919 0.000
E21.0 Primary hyperparathyroidism
0.000 0.919 0.081
G93.6 Cerebral oedema
0.080 0.920 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.080 0.920 0.000
E87.7 Fluid overload
0.000 0.920 0.080
E26.9 Hyperaldosteronism, unspecified
0.001 0.920 0.079
M49 Spondylopathies in diseases classified elsewhere
0.080 0.920 0.000
G92 Toxic encephalopathy
0.080 0.920 0.000
E87.5 Hyperkalaemia
0.000 0.921 0.079
G91.3 Posttraumatic hydrocephalus, unspecified
0.079 0.921 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.079 0.921 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.078 0.921 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.078 0.922 0.000
G96 Other disorders of central nervous system
0.078 0.922 0.000
E83.4 Disorders of magnesium metabolism
0.001 0.923 0.076
G91.0 Communicating hydrocephalus
0.077 0.923 0.000
E66.8 Other obesity
0.000 0.924 0.076
E26.0 Primary hyperaldosteronism
0.001 0.924 0.075
D86.9 Sarcoidosis, unspecified
0.000 0.925 0.075
M46.40 Discitis, unspecified (Multiple sites in spine)
0.074 0.926 0.000
G95.9 Disease of spinal cord, unspecified
0.074 0.926 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.073 0.927 0.000
D86 Sarcoidosis
0.000 0.927 0.073
G90.8 Other disorders of autonomic nervous system
0.072 0.928 0.000
G90.4 Autonomic dysreflexia
0.072 0.928 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.072 0.928 0.000
E28.9 Ovarian dysfunction, unspecified
0.001 0.928 0.071
E28.8 Other ovarian dysfunction
0.001 0.928 0.071
E28.1 Androgen excess
0.001 0.928 0.071
E28.0 Oestrogen excess
0.001 0.928 0.071
G97.8 Other postprocedural disorders of nervous system
0.071 0.929 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.071 0.929 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.070 0.930 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.070 0.930 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.070 0.930 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.070 0.930 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.070 0.930 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.070 0.930 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.070 0.930 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.070 0.930 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.070 0.930 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.068 0.932 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.068 0.932 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.068 0.932 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.068 0.932 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.068 0.932 0.000
M46.42 Discitis, unspecified (Cervical region)
0.068 0.932 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.068 0.932 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.068 0.932 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.068 0.932 0.000
G94.1 Hydrocephalus in neoplastic disease
0.067 0.932 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.933 0.067
D86.1 Sarcoidosis of lymph nodes
0.000 0.935 0.065
E21.3 Hyperparathyroidism, unspecified
0.000 0.935 0.065
G93.3 Postviral fatigue syndrome
0.064 0.935 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.064 0.936 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.064 0.936 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.064 0.936 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.064 0.936 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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