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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263473
log Bayes Factor = 73.4732
Chromosome 6   position 31,050,179  (GRCh37) Explore rs9263473 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.002 0.998
E10.9 Without complications
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.006 0.994
L40 Psoriasis
0.000 0.010 0.990
D86.9 Sarcoidosis, unspecified
0.000 0.010 0.990
D86 Sarcoidosis
0.000 0.010 0.990
D80-D89 Certain disorders involving the immune mechanism
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.048 0.020 0.932
L40.5 Arthropathic psoriasis
0.000 0.023 0.977
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.023 0.977
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.028 0.972
D70 Agranulocytosis
0.000 0.032 0.968
L40.0 Psoriasis vulgaris
0.000 0.055 0.945
E05 Thyrotoxicosis [hyperthyroidism]
0.008 0.061 0.931
D50-D53 Nutritional anaemias
0.000 0.062 0.938
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.064 0.935
D51 Vitamin B12 deficiency anaemia
0.000 0.082 0.918
D86.1 Sarcoidosis of lymph nodes
0.000 0.087 0.913
E11 Non-insulin-dependent diabetes mellitus
0.000 0.100 0.900
E10.2 With renal complications
0.000 0.105 0.895
E10.8 With unspecified complications
0.000 0.106 0.894
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.120 0.880
E10.4 With neurological complications
0.000 0.138 0.862
D72 Other disorders of white blood cells
0.000 0.152 0.847
E50-E64 Other nutritional deficiencies
0.000 0.164 0.836
D86.0 Sarcoidosis of lung
0.000 0.164 0.836
E10.5 With peripheral circulatory complications
0.000 0.170 0.830
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.178 0.822
E11.5 With peripheral circulatory complications
0.000 0.181 0.819
E11.3 With ophthalmic complications
0.000 0.182 0.818
E10.6 With other specified complications
0.000 0.185 0.815
D80 Immunodeficiency with predominantly antibody defects
0.000 0.195 0.805
D75 Other diseases of blood and blood-forming organs
0.000 0.197 0.803
D55-D59 Haemolytic anaemias
0.000 0.203 0.796
D86.8 Sarcoidosis of other and combined sites
0.000 0.210 0.790
E11.4 With neurological complications
0.000 0.215 0.785
E55 Vitamin D deficiency
0.000 0.219 0.781
D53 Other nutritional anaemias
0.000 0.220 0.780
D83 Common variable immunodeficiency
0.000 0.224 0.776
E03 Other hypothyroidism
0.413 0.233 0.354
D86.3 Sarcoidosis of skin
0.000 0.233 0.767
D72.8 Other specified disorders of white blood cells
0.000 0.234 0.766
E10.0 With coma
0.000 0.235 0.765
L40.4 Guttate psoriasis
0.000 0.235 0.764
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.241 0.759
D59 Acquired haemolytic anaemia
0.000 0.250 0.750
E55.9 Vitamin D deficiency, unspecified
0.000 0.258 0.742
L40.1 Generalised pustular psoriasis
0.000 0.261 0.738
E11.8 With unspecified complications
0.000 0.270 0.730
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E11.1 With ketoacidosis
0.000 0.287 0.713
E14 Unspecified diabetes mellitus
0.000 0.287 0.713
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.289 0.711
L40.3 Pustulosis palmaris et plantaris
0.000 0.290 0.710
L40.2 Acrodermatitis continua
0.000 0.290 0.710
E13 Other specified diabetes mellitus
0.000 0.293 0.707
D81 Combined immunodeficiencies
0.000 0.296 0.704
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.035 0.297 0.668
E00 Congenital iodine-deficiency syndrome
0.035 0.297 0.668
D74 Methaemoglobinaemia
0.000 0.303 0.697
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.303 0.697
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.303 0.697
E40-E46 Malnutrition
0.000 0.309 0.691
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.313 0.687
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.316 0.684
E16.1 Other hypoglycaemia
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.034 0.321 0.646
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.322 0.678
D82 Immunodeficiency associated with other major defects
0.000 0.326 0.674
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.326 0.674
E05.5 Thyroid crisis or storm
0.006 0.327 0.667
E05.4 Thyrotoxicosis factitia
0.006 0.327 0.667
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.006 0.327 0.667
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.006 0.327 0.667
E11.6 With other specified complications
0.000 0.332 0.668
D53.9 Nutritional anaemia, unspecified
0.000 0.334 0.666
E06 Thyroiditis
0.025 0.341 0.633
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.341 0.658
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.341 0.658
D51.2 Transcobalamin II deficiency
0.000 0.341 0.658
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.341 0.658
D59.1 Other autoimmune haemolytic anaemias
0.000 0.349 0.651
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.349 0.651
E11.7 With multiple complications
0.000 0.355 0.645
E83.1 Disorders of iron metabolism
0.000 0.356 0.644
E05.8 Other thyrotoxicosis
0.006 0.366 0.629
E53 Deficiency of other B group vitamins
0.000 0.367 0.633
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.368 0.632
D75.0 Familial erythrocytosis
0.000 0.369 0.631
E51 Thiamine deficiency
0.000 0.371 0.629
D83.9 Common variable immunodeficiency, unspecified
0.000 0.371 0.628
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.376 0.624
E70-E90 Metabolic disorders
0.000 0.378 0.622
E83 Disorders of mineral metabolism
0.000 0.388 0.612
D72.9 Disorder of white blood cells, unspecified
0.000 0.392 0.608
D72.0 Genetic anomalies of leukocytes
0.000 0.392 0.608
E14.3 With ophthalmic complications
0.000 0.395 0.605
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.400 0.600
E63 Other nutritional deficiencies
0.000 0.400 0.600
E50 Vitamin A deficiency
0.000 0.400 0.600
E60 Dietary zinc deficiency
0.000 0.400 0.600
E59 Dietary selenium deficiency
0.000 0.400 0.600
E52 Niacin deficiency [pellagra]
0.000 0.400 0.600
D50 Iron deficiency anaemia
0.000 0.401 0.599
D84 Other immunodeficiencies
0.000 0.404 0.596
D69 Purpura and other haemorrhagic conditions
0.000 0.411 0.589
D72.1 Eosinophilia
0.000 0.414 0.585
D75.2 Essential thrombocytosis
0.000 0.416 0.583
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.422 0.578
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.423 0.577
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.423 0.577
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.423 0.577
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.423 0.577
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.423 0.577
E54 Ascorbic acid deficiency
0.000 0.424 0.576
D55 Anaemia due to enzyme disorders
0.000 0.429 0.571
E88 Other metabolic disorders
0.000 0.430 0.570
D66 Hereditary factor VIII deficiency
0.000 0.431 0.568
E14.8 With unspecified complications
0.000 0.434 0.566
E85 Amyloidosis
0.000 0.438 0.562
E55.0 Rickets, active
0.000 0.440 0.560
D53.8 Other specified nutritional anaemias
0.000 0.441 0.559
D53.2 Scorbutic anaemia
0.000 0.441 0.559
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.441 0.559
D53.0 Protein deficiency anaemia
0.000 0.441 0.559
D83.8 Other common variable immunodeficiencies
0.000 0.443 0.556
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.443 0.556
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.443 0.556
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.443 0.556
E07 Other disorders of thyroid
0.064 0.444 0.491
E06.9 Thyroiditis, unspecified
0.011 0.446 0.544
E58 Dietary calcium deficiency
0.000 0.448 0.552
E14.1 With ketoacidosis
0.000 0.448 0.552
E65-E68 Obesity and other hyperalimentation
0.000 0.450 0.550
E03.5 Myxoedema coma
0.296 0.450 0.254
E03.4 Atrophy of thyroid (acquired)
0.296 0.450 0.254
E03.3 Postinfectious hypothyroidism
0.296 0.450 0.254
E56 Other vitamin deficiencies
0.000 0.454 0.546
D57 Sickle-cell disorders
0.000 0.455 0.544
E03.0 Congenital hypothyroidism with diffuse goitre
0.293 0.459 0.248
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.459 0.541
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.461 0.539
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.461 0.539
D59.8 Other acquired haemolytic anaemias
0.000 0.462 0.538
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.462 0.538
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.462 0.538
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.462 0.538
D59.3 Haemolytic-uraemic syndrome
0.000 0.462 0.538
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.462 0.538
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.462 0.538
E03.1 Congenital hypothyroidism without goitre
0.261 0.467 0.272
E13.9 Without complications
0.000 0.468 0.532
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.006 0.473 0.522
L40.8 Other psoriasis
0.000 0.474 0.525
E14.6 With other specified complications
0.000 0.475 0.525
D75.1 Secondary polycythaemia
0.000 0.475 0.525
E20-E35 Disorders of other endocrine glands
0.000 0.475 0.525
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.476 0.524
D67 Hereditary factor IX deficiency
0.000 0.480 0.520
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.306 0.480 0.213
E27.1 Primary adrenocortical insufficiency
0.000 0.481 0.519
E27 Other disorders of adrenal gland
0.000 0.484 0.516
E85.4 Organ-limited amyloidosis
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E14.7 With multiple complications
0.000 0.489 0.511
E14.2 Withrenal complications
0.000 0.489 0.511
E14.0 With coma
0.000 0.489 0.511
D58 Other hereditary haemolytic anaemias
0.000 0.491 0.509
D69.6 Thrombocytopenia, unspecified
0.000 0.492 0.508
E13.8 With unspecified complications
0.000 0.493 0.507
E13.7 With multiple complications
0.000 0.493 0.507
E13.6 With other specified complications
0.000 0.493 0.507
E13.5 With peripheral circulatory complications
0.000 0.493 0.507
E13.4 With neurological complications
0.000 0.493 0.507
E13.2 With renal complications
0.000 0.493 0.507
E13.1 With ketoacidosis
0.000 0.493 0.507
E13.0 With coma
0.000 0.493 0.507
E04 Other non-toxic goitre
0.003 0.494 0.503
D81.9 Combined immunodeficiency, unspecified
0.000 0.495 0.505
D81.8 Other combined immunodeficiencies
0.000 0.495 0.505
D81.7 Major histocompatibility complex class II deficiency
0.000 0.495 0.505
D81.6 Major histocompatibility complex class I deficiency
0.000 0.495 0.505
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.495 0.505
D81.4 Nezelof's syndrome
0.000 0.495 0.505
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.495 0.505
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.495 0.505
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.495 0.505
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.495 0.505
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.025 0.496 0.479
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.025 0.496 0.479
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.025 0.496 0.479
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.025 0.496 0.479
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.025 0.496 0.479
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.025 0.496 0.479
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.025 0.496 0.479
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.025 0.496 0.479
D74.9 Methaemoglobinaemia, unspecified
0.000 0.500 0.500
D74.8 Other methaemoglobinaemias
0.000 0.500 0.500
D74.0 Congenital methaemoglobinaemia
0.000 0.500 0.500
E05.9 Thyrotoxicosis, unspecified
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.505 0.495
E45 Retarded development following protein-energy malnutrition
0.000 0.505 0.495
E43 Unspecified severe protein-energy malnutrition
0.000 0.505 0.495
E42 Marasmic kwashiorkor
0.000 0.505 0.495
E41 Nutritional marasmus
0.000 0.505 0.495
E40 Kwashiorkor
0.000 0.505 0.495
D50.9 Iron deficiency anaemia, unspecified
0.000 0.508 0.492
D69.2 Other nonthrombocytopenic purpura
0.000 0.508 0.492
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.510 0.489
E03.8 Other specified hypothyroidism
0.263 0.511 0.226
E53.9 Vitamin B deficiency, unspecified
0.000 0.513 0.487
D69.5 Secondary thrombocytopenia
0.000 0.514 0.486
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.516 0.483
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.516 0.483
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.516 0.483
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.516 0.483
D82.2 Immunodeficiency with short-limbed stature
0.000 0.516 0.483
D82.0 Wiskott-Aldrich syndrome
0.000 0.516 0.483
E51.2 Wernicke's encephalopathy
0.000 0.519 0.481
E14.5 With peripheral circulatory complications
0.000 0.528 0.472
E06.4 Drug-induced thyroiditis
0.018 0.528 0.454
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.018 0.528 0.454
E06.0 Acute thyroiditis
0.018 0.528 0.454
E14.4 With neurological complications
0.000 0.529 0.471
E46 Unspecified protein-energy malnutrition
0.000 0.530 0.470
E79 Disorders of purine and pyrimidine metabolism
0.000 0.530 0.469
E13.3 With ophthalmic complications
0.000 0.532 0.468
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.533 0.467
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.533 0.467
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.533 0.467
D84.1 Defects in the complement system
0.000 0.534 0.466
K90 Intestinal malabsorption
0.000 0.535 0.465
E70 Disorders of aromatic amino-acid metabolism
0.000 0.536 0.464
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.541 0.459
D52 Folate deficiency anaemia
0.000 0.542 0.458
D50.8 Other iron deficiency anaemias
0.000 0.543 0.457
E53.1 Pyridoxine deficiency
0.000 0.546 0.454
E53.0 Riboflavin deficiency
0.000 0.546 0.454
D82.1 Di George's syndrome
0.000 0.546 0.454
E53.8 Deficiency of other specified B group vitamins
0.000 0.546 0.454
E51.9 Thiamine deficiency, unspecified
0.000 0.549 0.451
E51.8 Other manifestations of thiamine deficiency
0.000 0.549 0.451
E51.1 Beriberi
0.000 0.549 0.451
E88.9 Metabolic disorder, unspecified
0.000 0.553 0.447
E77 Disorders of glycoprotein metabolism
0.000 0.554 0.446
E76 Disorders of glycosaminoglycan metabolism
0.000 0.554 0.446
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.554 0.446
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.554 0.446
E34 Other endocrine disorders
0.000 0.558 0.441
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.560 0.440
E83.8 Other disorders of mineral metabolism
0.000 0.561 0.439
E83.2 Disorders of zinc metabolism
0.000 0.561 0.439
E83.0 Disorders of copper metabolism
0.000 0.561 0.439
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.565 0.435
D69.9 Haemorrhagic condition, unspecified
0.000 0.565 0.435
E50.9 Vitamin A deficiency, unspecified
0.000 0.570 0.430
E50.8 Other manifestations of vitamin A deficiency
0.000 0.570 0.430
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.570 0.430
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.570 0.430
E50.5 Vitamin A deficiency with night blindness
0.000 0.570 0.430
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.570 0.430
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.570 0.430
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.570 0.430
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.570 0.430
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.570 0.430
E63.9 Nutritional deficiency, unspecified
0.000 0.570 0.430
E63.8 Other specified nutritional deficiencies
0.000 0.570 0.430
E63.1 Imbalance of constituents of food intake
0.000 0.570 0.430
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.570 0.430
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.570 0.430
E64.8 Sequelae of other nutritional deficiencies
0.000 0.570 0.430
E64.3 Sequelae of rickets
0.000 0.570 0.430
E64.2 Sequelae of vitamin C deficiency
0.000 0.570 0.430
E64.1 Sequelae of vitamin A deficiency
0.000 0.570 0.430
E64.0 Sequelae of protein-energy malnutrition
0.000 0.570 0.430
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.570 0.430
D50.1 Sideropenic dysphagia
0.000 0.570 0.429
E07.8 Other specified disorders of thyroid
0.032 0.571 0.397
D84.8 Other specified immunodeficiencies
0.000 0.573 0.427
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.573 0.427
E06.3 Autoimmune thyroiditis
0.010 0.573 0.417
E61 Deficiency of other nutrient elements
0.000 0.573 0.427
E85.3 Secondary systemic amyloidosis
0.000 0.573 0.426
D69.8 Other specified haemorrhagic conditions
0.000 0.577 0.422
E04.0 Non-toxic diffuse goitre
0.001 0.578 0.420
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.578 0.421
D76.3 Other histiocytosis syndromes
0.000 0.579 0.421
E84 Cystic fibrosis
0.000 0.582 0.418
D89.3 Immune reconstitution syndrome
0.000 0.585 0.415
E20 Hypoparathyroidism
0.000 0.587 0.413
E06.1 Subacute thyroiditis
0.020 0.589 0.391
E72 Other disorders of amino-acid metabolism
0.000 0.590 0.410
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.590 0.409
D55.8 Other anaemias due to enzyme disorders
0.000 0.590 0.409
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.590 0.409
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.590 0.409
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.590 0.409
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.590 0.409
E88.3 Tumour lysis syndrome
0.000 0.593 0.407
E11.0 With coma
0.000 0.594 0.406
E85.8 Other amyloidosis
0.000 0.597 0.403
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.597 0.403
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.597 0.403
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.597 0.403
D69.1 Qualitative platelet defects
0.000 0.600 0.400
D89.1 Cryoglobulinaemia
0.000 0.600 0.400
E07.1 Dyshormogenetic goitre
0.046 0.601 0.352
E07.0 Hypersecretion of calcitonin
0.046 0.601 0.352
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.603 0.397
E04.9 Non-toxic goitre, unspecified
0.000 0.604 0.396
E67 Other hyperalimentation
0.000 0.605 0.394
E68 Sequelae of hyperalimentation
0.000 0.605 0.394
E56.9 Vitamin deficiency, unspecified
0.000 0.608 0.391
E56.8 Deficiency of other vitamins
0.000 0.608 0.391
E56.0 Deficiency of vitamin E
0.000 0.608 0.391
E06.5 Other chronic thyroiditis
0.021 0.609 0.371
E34.9 Endocrine disorder, unspecified
0.000 0.609 0.391
D57.8 Other sickle-cell disorders
0.000 0.609 0.390
D57.3 Sickle-cell trait
0.000 0.609 0.390
D57.2 Double heterozygous sickling disorders
0.000 0.609 0.390
D57.0 Sickle-cell anaemia with crisis
0.000 0.609 0.390
E85.9 Amyloidosis, unspecified
0.000 0.610 0.390
E25 Adrenogenital disorders
0.000 0.611 0.389
E88.8 Other specified metabolic disorders
0.000 0.612 0.388
E11.2 With renal complications
0.000 0.614 0.386
E74 Other disorders of carbohydrate metabolism
0.000 0.619 0.381
K90.9 Intestinal malabsorption, unspecified
0.000 0.623 0.377
D58.2 Other haemoglobinopathies
0.000 0.623 0.377
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.624 0.376
E32 Diseases of thymus
0.000 0.624 0.376
E31 Polyglandular dysfunction
0.000 0.624 0.376
E30 Disorders of puberty, not elsewhere classified
0.000 0.624 0.376
D69.4 Other primary thrombocytopenia
0.000 0.626 0.373
E27.5 Adrenomedullary hyperfunction
0.000 0.630 0.370
E27.0 Other adrenocortical overactivity
0.000 0.630 0.370
E66 Obesity
0.000 0.633 0.367
E27.2 Addisonian crisis
0.000 0.633 0.367
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.635 0.365
D58.1 Hereditary elliptocytosis
0.000 0.635 0.365
D57.1 Sickle-cell anaemia without crisis
0.000 0.636 0.364
E04.8 Other specified non-toxic goitre
0.002 0.637 0.361
D56 Thalassaemia
0.001 0.638 0.361
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.640 0.360
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.640 0.359
E44.1 Mild protein-energy malnutrition
0.000 0.645 0.355
E44.0 Moderate protein-energy malnutrition
0.000 0.645 0.355
E88.2 Lipomatosis, not elsewhere classified
0.000 0.645 0.355
E34.0 Carcinoid syndrome
0.000 0.646 0.354
E73 Lactose intolerance
0.000 0.650 0.350
E70.3 Albinism
0.000 0.650 0.350
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.658 0.341
E27.8 Other specified disorders of adrenal gland
0.000 0.660 0.340
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.660 0.340
E56.1 Deficiency of vitamin K
0.000 0.662 0.338
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.663 0.337
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.663 0.337
E79.1 Lesch-Nyhan syndrome
0.000 0.663 0.337
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.666 0.334
K90.3 Pancreatic steatorrhoea
0.000 0.666 0.334
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.666 0.334
K90.1 Tropical sprue
0.000 0.666 0.334
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.667 0.332
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.667 0.332
E70.2 Disorders of tyrosine metabolism
0.000 0.667 0.332
E70.1 Other hyperphenylalaninaemias
0.000 0.667 0.332
E70.0 Classical phenylketonuria
0.000 0.667 0.332
E20.9 Hypoparathyroidism, unspecified
0.000 0.668 0.332
E86 Volume depletion
0.000 0.669 0.331
D52.8 Other folate deficiency anaemias
0.000 0.671 0.328
D52.1 Drug-induced folate deficiency anaemia
0.000 0.671 0.328
D52.0 Dietary folate deficiency anaemia
0.000 0.671 0.328
D58.0 Hereditary spherocytosis
0.000 0.677 0.323
K90.8 Other intestinal malabsorption
0.000 0.678 0.322
E22 Hyperfunction of pituitary gland
0.000 0.678 0.322
E71.3 Disorders of fatty-acid metabolism
0.000 0.680 0.320
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.680 0.320
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.680 0.320
E71.0 Maple-syrup-urine disease
0.000 0.680 0.320
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.680 0.320
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.680 0.320
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.680 0.320
E76.2 Other mucopolysaccharidoses
0.000 0.680 0.320
E76.1 Mucopolysaccharidosis, type II
0.000 0.680 0.320
E76.0 Mucopolysaccharidosis, type I
0.000 0.680 0.320
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.680 0.320
E77.8 Other disorders of glycoprotein metabolism
0.000 0.680 0.320
E77.1 Defects in glycoprotein degradation
0.000 0.680 0.320
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.680 0.320
E24 Cushing's syndrome
0.000 0.683 0.317
E34.5 Androgen resistance syndrome
0.000 0.683 0.317
E34.4 Constitutional tall stature
0.000 0.683 0.317
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.683 0.317
E34.1 Other hypersecretion of intestinal hormones
0.000 0.683 0.317
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.686 0.314
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.691 0.309
E61.9 Deficiency of nutrient element, unspecified
0.000 0.694 0.306
E61.8 Deficiency of other specified nutrient elements
0.000 0.694 0.306
E61.7 Deficiency of multiple nutrient elements
0.000 0.694 0.306
E61.6 Vanadium deficiency
0.000 0.694 0.306
E61.5 Molybdenum deficiency
0.000 0.694 0.306
E61.4 Chromium deficiency
0.000 0.694 0.306
E61.3 Manganese deficiency
0.000 0.694 0.306
E61.0 Copper deficiency
0.000 0.694 0.306
E66.0 Obesity due to excess calories
0.000 0.694 0.306
E34.3 Short stature, not elsewhere classified
0.000 0.696 0.304
E84.8 Cystic fibrosis with other manifestations
0.000 0.700 0.300
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.700 0.300
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.700 0.300
E29 Testicular dysfunction
0.000 0.700 0.300
D60-D64 Aplastic and other anaemias
0.000 0.700 0.300
E20.8 Other hypoparathyroidism
0.000 0.704 0.296
E20.1 Pseudohypoparathyroidism
0.000 0.704 0.296
E20.0 Idiopathic hypoparathyroidism
0.000 0.704 0.296
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.704 0.295
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.706 0.294
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.706 0.294
E72.5 Disorders of glycine metabolism
0.000 0.706 0.294
E72.4 Disorders of ornithine metabolism
0.000 0.706 0.294
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.706 0.294
E72.2 Disorders of urea cycle metabolism
0.000 0.706 0.294
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.706 0.294
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.708 0.292
E67.8 Other specified hyperalimentation
0.000 0.717 0.283
E67.3 Hypervitaminosis D
0.000 0.717 0.283
E67.2 Megavitamin-B6 syndrome
0.000 0.717 0.283
E67.1 Hypercarotenaemia
0.000 0.717 0.283
E67.0 Hypervitaminosis A
0.000 0.717 0.283
E25.9 Adrenogenital disorder, unspecified
0.000 0.721 0.279
E25.8 Other adrenogenital disorders
0.000 0.721 0.279
E65 Localised adiposity
0.000 0.724 0.276
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.726 0.273
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.726 0.273
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.726 0.273
E74.2 Disorders of galactose metabolism
0.000 0.726 0.273
E74.1 Disorders of fructose metabolism
0.000 0.726 0.273
E74.0 Glycogen storage disease
0.000 0.726 0.273
E84.9 Cystic fibrosis, unspecified
0.000 0.728 0.272
E30.9 Disorder of puberty, unspecified
0.000 0.730 0.270
E30.8 Other disorders of puberty
0.000 0.730 0.270
E30.1 Precocious puberty
0.000 0.730 0.270
E30.0 Delayed puberty
0.000 0.730 0.270
E31.9 Polyglandular dysfunction, unspecified
0.000 0.730 0.270
E31.8 Other polyglandular dysfunction
0.000 0.730 0.270
E31.1 Polyglandular hyperfunction
0.000 0.730 0.270
E31.0 Autoimmune polyglandular failure
0.000 0.730 0.270
E32.9 Disease of thymus, unspecified
0.000 0.730 0.270
E32.8 Other diseases of thymus
0.000 0.730 0.270
E32.1 Abscess of thymus
0.000 0.730 0.270
E32.0 Persistent hyperplasia of thymus
0.000 0.730 0.270
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.730 0.270
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.730 0.270
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.730 0.270
E61.2 Magnesium deficiency
0.000 0.730 0.269
D73 Diseases of spleen
0.000 0.730 0.269
E66.1 Drug-induced obesity
0.000 0.736 0.264
E26 Hyperaldosteronism
0.000 0.737 0.263
D56.9 Thalassaemia, unspecified
0.001 0.740 0.259
D56.8 Other thalassaemias
0.001 0.740 0.259
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.001 0.740 0.259
D56.2 Delta-beta thalassaemia
0.001 0.740 0.259
D56.0 Alpha thalassaemia
0.001 0.740 0.259
E22.1 Hyperprolactinaemia
0.000 0.742 0.258
E75.6 Lipid storage disorder, unspecified
0.000 0.742 0.258
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.742 0.258
E75.3 Sphingolipidosis, unspecified
0.000 0.742 0.258
E75.1 Other gangliosidosis
0.000 0.742 0.258
E75.0 GM2 gangliosidosis
0.000 0.742 0.258
E72.0 Disorders of amino-acid transport
0.000 0.742 0.258
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.747 0.253
E73.8 Other lactose intolerance
0.000 0.749 0.251
E73.1 Secondary lactase deficiency
0.000 0.749 0.251
E73.0 Congenital lactase deficiency
0.000 0.749 0.251
E34.8 Other specified endocrine disorders
0.000 0.750 0.249
E24.0 Pituitary-dependent Cushing's disease
0.000 0.754 0.246
E66.8 Other obesity
0.000 0.757 0.243

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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