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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263474
log Bayes Factor = 72.0763
Chromosome 6   position 31,050,244  (GRCh37) Explore rs9263474 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.002 0.998
E10.9 Without complications
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E16.2 Hypoglycaemia, unspecified
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.006 0.994
D86.9 Sarcoidosis, unspecified
0.000 0.013 0.987
D86 Sarcoidosis
0.000 0.013 0.987
L40 Psoriasis
0.000 0.015 0.985
D80-D89 Certain disorders involving the immune mechanism
0.000 0.021 0.979
E00-E07 Disorders of thyroid gland
0.061 0.022 0.917
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.027 0.973
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.030 0.970
L40.5 Arthropathic psoriasis
0.000 0.031 0.969
D70 Agranulocytosis
0.000 0.033 0.967
L40.0 Psoriasis vulgaris
0.000 0.069 0.931
E05 Thyrotoxicosis [hyperthyroidism]
0.010 0.073 0.917
D50-D53 Nutritional anaemias
0.000 0.074 0.926
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.077 0.923
D86.1 Sarcoidosis of lymph nodes
0.000 0.090 0.910
E11 Non-insulin-dependent diabetes mellitus
0.000 0.091 0.909
D51 Vitamin B12 deficiency anaemia
0.000 0.104 0.896
E10.2 With renal complications
0.000 0.105 0.895
E10.8 With unspecified complications
0.000 0.107 0.893
E10.4 With neurological complications
0.000 0.139 0.861
D72 Other disorders of white blood cells
0.000 0.147 0.853
E10.5 With peripheral circulatory complications
0.000 0.157 0.843
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.163 0.837
E11.5 With peripheral circulatory complications
0.000 0.170 0.830
E50-E64 Other nutritional deficiencies
0.000 0.171 0.829
E11.3 With ophthalmic complications
0.000 0.180 0.820
E10.6 With other specified complications
0.000 0.185 0.815
D86.0 Sarcoidosis of lung
0.000 0.188 0.812
E11.4 With neurological complications
0.000 0.188 0.812
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.199 0.801
D80 Immunodeficiency with predominantly antibody defects
0.000 0.199 0.800
D75 Other diseases of blood and blood-forming organs
0.000 0.206 0.794
D53 Other nutritional anaemias
0.000 0.208 0.792
D55-D59 Haemolytic anaemias
0.000 0.208 0.792
D86.8 Sarcoidosis of other and combined sites
0.000 0.213 0.787
E55 Vitamin D deficiency
0.000 0.222 0.778
D72.8 Other specified disorders of white blood cells
0.000 0.223 0.777
D83 Common variable immunodeficiency
0.000 0.227 0.773
E03 Other hypothyroidism
0.423 0.231 0.346
E10.0 With coma
0.000 0.235 0.765
D86.3 Sarcoidosis of skin
0.000 0.236 0.764
L40.4 Guttate psoriasis
0.000 0.240 0.760
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.244 0.756
D59 Acquired haemolytic anaemia
0.000 0.255 0.745
E55.9 Vitamin D deficiency, unspecified
0.000 0.258 0.742
E11.8 With unspecified complications
0.000 0.262 0.738
L40.1 Generalised pustular psoriasis
0.000 0.266 0.734
E11.1 With ketoacidosis
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.291 0.709
L40.3 Pustulosis palmaris et plantaris
0.000 0.294 0.706
L40.2 Acrodermatitis continua
0.000 0.294 0.706
E13 Other specified diabetes mellitus
0.000 0.295 0.705
D81 Combined immunodeficiencies
0.000 0.298 0.702
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.044 0.299 0.657
E00 Congenital iodine-deficiency syndrome
0.044 0.299 0.657
E14 Unspecified diabetes mellitus
0.000 0.300 0.700
D53.9 Nutritional anaemia, unspecified
0.000 0.303 0.697
D74 Methaemoglobinaemia
0.000 0.305 0.695
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.305 0.695
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.305 0.695
E40-E46 Malnutrition
0.000 0.311 0.689
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.317 0.683
E16.1 Other hypoglycaemia
0.000 0.319 0.681
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.322 0.678
E02 Subclinical iodine-deficiency hypothyroidism
0.042 0.323 0.635
E11.6 With other specified complications
0.000 0.326 0.674
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.326 0.674
D82 Immunodeficiency associated with other major defects
0.000 0.328 0.672
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.330 0.670
E05.5 Thyroid crisis or storm
0.007 0.336 0.657
E05.4 Thyrotoxicosis factitia
0.007 0.336 0.657
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.007 0.336 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.007 0.336 0.657
E11.7 With multiple complications
0.000 0.348 0.652
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.351 0.649
D59.1 Other autoimmune haemolytic anaemias
0.000 0.353 0.647
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.358 0.642
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.358 0.642
D51.2 Transcobalamin II deficiency
0.000 0.358 0.642
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.358 0.642
E06 Thyroiditis
0.033 0.360 0.607
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.372 0.628
D83.9 Common variable immunodeficiency, unspecified
0.000 0.374 0.626
E05.8 Other thyrotoxicosis
0.007 0.374 0.618
E51 Thiamine deficiency
0.000 0.376 0.624
D75.0 Familial erythrocytosis
0.000 0.377 0.623
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.379 0.620
E53 Deficiency of other B group vitamins
0.000 0.388 0.612
D72.9 Disorder of white blood cells, unspecified
0.000 0.388 0.612
D72.0 Genetic anomalies of leukocytes
0.000 0.388 0.612
D50 Iron deficiency anaemia
0.000 0.389 0.611
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.406 0.594
E63 Other nutritional deficiencies
0.000 0.406 0.594
E50 Vitamin A deficiency
0.000 0.406 0.594
E60 Dietary zinc deficiency
0.000 0.406 0.594
E59 Dietary selenium deficiency
0.000 0.406 0.594
E52 Niacin deficiency [pellagra]
0.000 0.406 0.594
D84 Other immunodeficiencies
0.000 0.406 0.593
D72.1 Eosinophilia
0.000 0.411 0.589
E14.3 With ophthalmic complications
0.000 0.416 0.584
D69 Purpura and other haemorrhagic conditions
0.000 0.420 0.580
D75.2 Essential thrombocytosis
0.000 0.424 0.576
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.426 0.574
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.426 0.574
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.426 0.574
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.426 0.574
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.426 0.574
E54 Ascorbic acid deficiency
0.000 0.429 0.571
D53.8 Other specified nutritional anaemias
0.000 0.432 0.568
D53.2 Scorbutic anaemia
0.000 0.432 0.568
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.432 0.568
D53.0 Protein deficiency anaemia
0.000 0.432 0.568
D55 Anaemia due to enzyme disorders
0.000 0.432 0.568
D66 Hereditary factor VIII deficiency
0.000 0.434 0.566
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.436 0.563
E55.0 Rickets, active
0.000 0.442 0.558
E14.8 With unspecified complications
0.000 0.445 0.555
D83.8 Other common variable immunodeficiencies
0.000 0.446 0.554
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.446 0.554
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.446 0.554
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.446 0.554
E03.5 Myxoedema coma
0.303 0.449 0.248
E03.4 Atrophy of thyroid (acquired)
0.303 0.449 0.248
E03.3 Postinfectious hypothyroidism
0.303 0.449 0.248
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.450 0.550
E58 Dietary calcium deficiency
0.000 0.453 0.547
E65-E68 Obesity and other hyperalimentation
0.000 0.457 0.543
E03.0 Congenital hypothyroidism with diffuse goitre
0.300 0.458 0.242
D57 Sickle-cell disorders
0.000 0.458 0.541
E14.1 With ketoacidosis
0.000 0.459 0.541
E56 Other vitamin deficiencies
0.000 0.459 0.541
E83.1 Disorders of iron metabolism
0.000 0.460 0.540
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.464 0.536
E07 Other disorders of thyroid
0.079 0.465 0.455
D59.8 Other acquired haemolytic anaemias
0.000 0.465 0.534
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.465 0.534
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.465 0.534
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.465 0.534
D59.3 Haemolytic-uraemic syndrome
0.000 0.465 0.534
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.465 0.534
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.465 0.534
E03.1 Congenital hypothyroidism without goitre
0.267 0.467 0.266
E13.9 Without complications
0.000 0.471 0.529
E20-E35 Disorders of other endocrine glands
0.000 0.472 0.528
E06.9 Thyroiditis, unspecified
0.014 0.473 0.513
D75.1 Secondary polycythaemia
0.000 0.477 0.523
L40.8 Other psoriasis
0.000 0.477 0.522
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.314 0.478 0.208
E27.1 Primary adrenocortical insufficiency
0.000 0.479 0.521
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.007 0.481 0.512
E27 Other disorders of adrenal gland
0.000 0.481 0.518
D67 Hereditary factor IX deficiency
0.000 0.482 0.518
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.482 0.518
E14.6 With other specified complications
0.000 0.485 0.515
E70-E90 Metabolic disorders
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.8 With unspecified complications
0.000 0.494 0.506
E13.7 With multiple complications
0.000 0.494 0.506
E13.6 With other specified complications
0.000 0.494 0.506
E13.5 With peripheral circulatory complications
0.000 0.494 0.506
E13.4 With neurological complications
0.000 0.494 0.506
E13.2 With renal complications
0.000 0.494 0.506
E13.1 With ketoacidosis
0.000 0.494 0.506
E13.0 With coma
0.000 0.494 0.506
D58 Other hereditary haemolytic anaemias
0.000 0.494 0.505
E83 Disorders of mineral metabolism
0.000 0.495 0.505
D50.9 Iron deficiency anaemia, unspecified
0.000 0.496 0.504
D81.9 Combined immunodeficiency, unspecified
0.000 0.497 0.503
D81.8 Other combined immunodeficiencies
0.000 0.497 0.503
D81.7 Major histocompatibility complex class II deficiency
0.000 0.497 0.503
D81.6 Major histocompatibility complex class I deficiency
0.000 0.497 0.503
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.497 0.503
D81.4 Nezelof's syndrome
0.000 0.497 0.503
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.497 0.503
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.497 0.503
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.497 0.503
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.497 0.503
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.031 0.497 0.471
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.031 0.497 0.471
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.031 0.497 0.471
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.031 0.497 0.471
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.031 0.497 0.471
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.031 0.497 0.471
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.031 0.497 0.471
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.031 0.497 0.471
E14.7 With multiple complications
0.000 0.498 0.502
E14.2 Withrenal complications
0.000 0.498 0.502
E14.0 With coma
0.000 0.498 0.502
D74.9 Methaemoglobinaemia, unspecified
0.000 0.501 0.499
D74.8 Other methaemoglobinaemias
0.000 0.501 0.499
D74.0 Congenital methaemoglobinaemia
0.000 0.501 0.499
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
D69.6 Thrombocytopenia, unspecified
0.000 0.509 0.491
E05.9 Thyrotoxicosis, unspecified
0.000 0.510 0.490
E03.8 Other specified hypothyroidism
0.270 0.510 0.220
E04 Other non-toxic goitre
0.004 0.512 0.484
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.513 0.487
D69.2 Other nonthrombocytopenic purpura
0.000 0.516 0.484
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.518 0.482
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.518 0.482
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.518 0.482
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.518 0.482
D82.2 Immunodeficiency with short-limbed stature
0.000 0.518 0.482
D82.0 Wiskott-Aldrich syndrome
0.000 0.518 0.482
D50.8 Other iron deficiency anaemias
0.000 0.519 0.481
D69.5 Secondary thrombocytopenia
0.000 0.522 0.478
E51.2 Wernicke's encephalopathy
0.000 0.523 0.477
E53.9 Vitamin B deficiency, unspecified
0.000 0.529 0.471
E88 Other metabolic disorders
0.000 0.531 0.469
E46 Unspecified protein-energy malnutrition
0.000 0.532 0.468
E13.3 With ophthalmic complications
0.000 0.534 0.466
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.534 0.465
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.534 0.465
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.534 0.465
D84.1 Defects in the complement system
0.000 0.536 0.464
E14.5 With peripheral circulatory complications
0.000 0.536 0.464
E14.4 With neurological complications
0.000 0.538 0.462
K90 Intestinal malabsorption
0.000 0.538 0.462
E06.4 Drug-induced thyroiditis
0.023 0.541 0.436
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.023 0.541 0.436
E06.0 Acute thyroiditis
0.023 0.541 0.436
D52 Folate deficiency anaemia
0.000 0.545 0.455
E85 Amyloidosis
0.000 0.545 0.455
D82.1 Di George's syndrome
0.000 0.548 0.452
E34 Other endocrine disorders
0.000 0.548 0.452
E51.9 Thiamine deficiency, unspecified
0.000 0.553 0.447
E51.8 Other manifestations of thiamine deficiency
0.000 0.553 0.447
E51.1 Beriberi
0.000 0.553 0.447
E53.1 Pyridoxine deficiency
0.000 0.561 0.439
E53.0 Riboflavin deficiency
0.000 0.561 0.439
D50.1 Sideropenic dysphagia
0.000 0.562 0.438
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.565 0.435
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.571 0.429
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.572 0.428
D69.9 Haemorrhagic condition, unspecified
0.000 0.572 0.428
E50.9 Vitamin A deficiency, unspecified
0.000 0.574 0.426
E50.8 Other manifestations of vitamin A deficiency
0.000 0.574 0.426
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.574 0.426
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.574 0.426
E50.5 Vitamin A deficiency with night blindness
0.000 0.574 0.426
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.574 0.426
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.574 0.426
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.574 0.426
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.574 0.426
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.574 0.426
E63.9 Nutritional deficiency, unspecified
0.000 0.574 0.426
E63.8 Other specified nutritional deficiencies
0.000 0.574 0.426
E63.1 Imbalance of constituents of food intake
0.000 0.574 0.426
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.574 0.426
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.574 0.426
E64.8 Sequelae of other nutritional deficiencies
0.000 0.574 0.426
E64.3 Sequelae of rickets
0.000 0.574 0.426
E64.2 Sequelae of vitamin C deficiency
0.000 0.574 0.426
E64.1 Sequelae of vitamin A deficiency
0.000 0.574 0.426
E64.0 Sequelae of protein-energy malnutrition
0.000 0.574 0.426
D84.8 Other specified immunodeficiencies
0.000 0.574 0.425
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.574 0.425
E53.8 Deficiency of other specified B group vitamins
0.000 0.578 0.422
D76.3 Other histiocytosis syndromes
0.000 0.581 0.419
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.581 0.419
E06.3 Autoimmune thyroiditis
0.013 0.583 0.404
D69.8 Other specified haemorrhagic conditions
0.000 0.584 0.416
E20 Hypoparathyroidism
0.000 0.586 0.414
E11.0 With coma
0.000 0.590 0.410
E34.9 Endocrine disorder, unspecified
0.000 0.591 0.409
E85.4 Organ-limited amyloidosis
0.000 0.591 0.409
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.592 0.407
D55.8 Other anaemias due to enzyme disorders
0.000 0.592 0.407
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.592 0.407
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.592 0.407
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.592 0.407
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.592 0.407
E61 Deficiency of other nutrient elements
0.000 0.594 0.406
E04.0 Non-toxic diffuse goitre
0.002 0.595 0.403
D89.3 Immune reconstitution syndrome
0.000 0.596 0.404
E06.1 Subacute thyroiditis
0.026 0.599 0.375
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.602 0.398
E07.8 Other specified disorders of thyroid
0.042 0.602 0.356
D69.1 Qualitative platelet defects
0.000 0.607 0.393
E25 Adrenogenital disorders
0.000 0.609 0.391
E67 Other hyperalimentation
0.000 0.611 0.389
E68 Sequelae of hyperalimentation
0.000 0.611 0.389
D89.1 Cryoglobulinaemia
0.000 0.611 0.389
E79 Disorders of purine and pyrimidine metabolism
0.000 0.611 0.389
D57.8 Other sickle-cell disorders
0.000 0.612 0.388
D57.3 Sickle-cell trait
0.000 0.612 0.388
D57.2 Double heterozygous sickling disorders
0.000 0.612 0.388
D57.0 Sickle-cell anaemia with crisis
0.000 0.612 0.388
E11.2 With renal complications
0.000 0.612 0.388
E56.9 Vitamin deficiency, unspecified
0.000 0.612 0.388
E56.8 Deficiency of other vitamins
0.000 0.612 0.388
E56.0 Deficiency of vitamin E
0.000 0.612 0.388
E70 Disorders of aromatic amino-acid metabolism
0.000 0.616 0.384
E07.1 Dyshormogenetic goitre
0.057 0.616 0.327
E07.0 Hypersecretion of calcitonin
0.057 0.616 0.327
E06.5 Other chronic thyroiditis
0.027 0.618 0.355
E04.9 Non-toxic goitre, unspecified
0.000 0.619 0.381
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.621 0.379
E32 Diseases of thymus
0.000 0.621 0.379
E31 Polyglandular dysfunction
0.000 0.621 0.379
E30 Disorders of puberty, not elsewhere classified
0.000 0.621 0.379
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.623 0.377
D58.2 Other haemoglobinopathies
0.000 0.625 0.374
K90.9 Intestinal malabsorption, unspecified
0.000 0.626 0.374
E27.5 Adrenomedullary hyperfunction
0.000 0.628 0.372
E27.0 Other adrenocortical overactivity
0.000 0.628 0.372
E77 Disorders of glycoprotein metabolism
0.000 0.630 0.369
E76 Disorders of glycosaminoglycan metabolism
0.000 0.630 0.369
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.630 0.369
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.630 0.369
E27.2 Addisonian crisis
0.000 0.632 0.368
D69.4 Other primary thrombocytopenia
0.000 0.633 0.367
E88.9 Metabolic disorder, unspecified
0.000 0.633 0.367
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.637 0.362
D58.1 Hereditary elliptocytosis
0.000 0.637 0.362
E83.8 Other disorders of mineral metabolism
0.000 0.637 0.362
E83.2 Disorders of zinc metabolism
0.000 0.637 0.362
E83.0 Disorders of copper metabolism
0.000 0.637 0.362
D57.1 Sickle-cell anaemia without crisis
0.000 0.638 0.362
D56 Thalassaemia
0.001 0.640 0.359
E34.0 Carcinoid syndrome
0.000 0.646 0.354
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.354
E66 Obesity
0.000 0.650 0.350
E04.8 Other specified non-toxic goitre
0.003 0.650 0.347
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.652 0.348
E84 Cystic fibrosis
0.000 0.654 0.346
E85.3 Secondary systemic amyloidosis
0.000 0.655 0.345
E72 Other disorders of amino-acid metabolism
0.000 0.660 0.339
E56.1 Deficiency of vitamin K
0.000 0.665 0.335
E88.3 Tumour lysis syndrome
0.000 0.665 0.335
E20.9 Hypoparathyroidism, unspecified
0.000 0.667 0.333
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.667 0.333
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.668 0.332
K90.3 Pancreatic steatorrhoea
0.000 0.669 0.331
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.669 0.331
K90.1 Tropical sprue
0.000 0.669 0.331
E27.8 Other specified disorders of adrenal gland
0.000 0.669 0.331
D52.8 Other folate deficiency anaemias
0.000 0.673 0.326
D52.1 Drug-induced folate deficiency anaemia
0.000 0.673 0.326
D52.0 Dietary folate deficiency anaemia
0.000 0.673 0.326
E85.8 Other amyloidosis
0.000 0.673 0.326
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.673 0.326
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.673 0.326
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.673 0.326
E34.5 Androgen resistance syndrome
0.000 0.676 0.324
E34.4 Constitutional tall stature
0.000 0.676 0.324
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.676 0.324
E34.1 Other hypersecretion of intestinal hormones
0.000 0.676 0.324
E22 Hyperfunction of pituitary gland
0.000 0.678 0.322
D58.0 Hereditary spherocytosis
0.000 0.679 0.321
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.680 0.320
K90.8 Other intestinal malabsorption
0.000 0.680 0.320
E88.8 Other specified metabolic disorders
0.000 0.681 0.319
E24 Cushing's syndrome
0.000 0.682 0.318
E74 Other disorders of carbohydrate metabolism
0.000 0.685 0.315
E85.9 Amyloidosis, unspecified
0.000 0.685 0.315
E34.3 Short stature, not elsewhere classified
0.000 0.689 0.311
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.691 0.309
E29 Testicular dysfunction
0.000 0.700 0.299
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.701 0.299
D60-D64 Aplastic and other anaemias
0.000 0.701 0.299
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.702 0.298
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.702 0.297
E20.8 Other hypoparathyroidism
0.000 0.703 0.297
E20.1 Pseudohypoparathyroidism
0.000 0.703 0.297
E20.0 Idiopathic hypoparathyroidism
0.000 0.703 0.297
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.707 0.293
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.707 0.293
E66.0 Obesity due to excess calories
0.000 0.708 0.292
E61.9 Deficiency of nutrient element, unspecified
0.000 0.709 0.291
E61.8 Deficiency of other specified nutrient elements
0.000 0.709 0.291
E61.7 Deficiency of multiple nutrient elements
0.000 0.709 0.291
E61.6 Vanadium deficiency
0.000 0.709 0.291
E61.5 Molybdenum deficiency
0.000 0.709 0.291
E61.4 Chromium deficiency
0.000 0.709 0.291
E61.3 Manganese deficiency
0.000 0.709 0.291
E61.0 Copper deficiency
0.000 0.709 0.291
E70.3 Albinism
0.000 0.710 0.289
E73 Lactose intolerance
0.000 0.711 0.289
E88.2 Lipomatosis, not elsewhere classified
0.000 0.713 0.287
E65 Localised adiposity
0.000 0.717 0.283
E25.9 Adrenogenital disorder, unspecified
0.000 0.719 0.281
E25.8 Other adrenogenital disorders
0.000 0.719 0.281
E67.8 Other specified hyperalimentation
0.000 0.721 0.279
E67.3 Hypervitaminosis D
0.000 0.721 0.279
E67.2 Megavitamin-B6 syndrome
0.000 0.721 0.279
E67.1 Hypercarotenaemia
0.000 0.721 0.279
E67.0 Hypervitaminosis A
0.000 0.721 0.279
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.721 0.279
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.721 0.279
E79.1 Lesch-Nyhan syndrome
0.000 0.721 0.279
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.725 0.275
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.725 0.275
E70.2 Disorders of tyrosine metabolism
0.000 0.725 0.275
E70.1 Other hyperphenylalaninaemias
0.000 0.725 0.275
E70.0 Classical phenylketonuria
0.000 0.725 0.275
E30.9 Disorder of puberty, unspecified
0.000 0.728 0.271
E30.8 Other disorders of puberty
0.000 0.728 0.271
E30.1 Precocious puberty
0.000 0.728 0.271
E30.0 Delayed puberty
0.000 0.728 0.271
E31.9 Polyglandular dysfunction, unspecified
0.000 0.728 0.271
E31.8 Other polyglandular dysfunction
0.000 0.728 0.271
E31.1 Polyglandular hyperfunction
0.000 0.728 0.271
E31.0 Autoimmune polyglandular failure
0.000 0.728 0.271
E32.9 Disease of thymus, unspecified
0.000 0.728 0.271
E32.8 Other diseases of thymus
0.000 0.728 0.271
E32.1 Abscess of thymus
0.000 0.728 0.271
E32.0 Persistent hyperplasia of thymus
0.000 0.728 0.271
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.728 0.271
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.728 0.271
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.728 0.271
D73 Diseases of spleen
0.000 0.730 0.270
E26 Hyperaldosteronism
0.000 0.733 0.267
E71.3 Disorders of fatty-acid metabolism
0.000 0.735 0.265
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.735 0.265
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.735 0.265
E71.0 Maple-syrup-urine disease
0.000 0.735 0.265
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.735 0.265
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.735 0.265
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.735 0.265
E76.2 Other mucopolysaccharidoses
0.000 0.735 0.265
E76.1 Mucopolysaccharidosis, type II
0.000 0.735 0.265
E76.0 Mucopolysaccharidosis, type I
0.000 0.735 0.265
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.735 0.265
E77.8 Other disorders of glycoprotein metabolism
0.000 0.735 0.265
E77.1 Defects in glycoprotein degradation
0.000 0.735 0.265
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.735 0.265
E22.1 Hyperprolactinaemia
0.000 0.741 0.259
D56.9 Thalassaemia, unspecified
0.001 0.742 0.257
D56.8 Other thalassaemias
0.001 0.742 0.257
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.001 0.742 0.257
D56.2 Delta-beta thalassaemia
0.001 0.742 0.257
D56.0 Alpha thalassaemia
0.001 0.742 0.257
E34.8 Other specified endocrine disorders
0.000 0.745 0.255
E66.1 Drug-induced obesity
0.000 0.749 0.251
E84.8 Cystic fibrosis with other manifestations
0.000 0.752 0.248
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.752 0.248
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.752 0.248
E24.0 Pituitary-dependent Cushing's disease
0.000 0.753 0.247
E86 Volume depletion
0.000 0.754 0.246
E61.2 Magnesium deficiency
0.000 0.756 0.243
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.756 0.243
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.756 0.243
E72.5 Disorders of glycine metabolism
0.000 0.756 0.243
E72.4 Disorders of ornithine metabolism
0.000 0.756 0.243
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.756 0.243
E72.2 Disorders of urea cycle metabolism
0.000 0.756 0.243
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.756 0.243
E27.9 Disorder of adrenal gland, unspecified
0.000 0.760 0.239
D84.9 Immunodeficiency, unspecified
0.001 0.765 0.234
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.769 0.231
E22.8 Other hyperfunction of pituitary gland
0.000 0.769 0.231
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.772 0.228
E24.3 Ectopic ACTH syndrome
0.000 0.772 0.228
E24.1 Nelson's syndrome
0.000 0.772 0.228
S64.4 Injury of digital nerve of other finger
0.228 0.772 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.774 0.226
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.774 0.226
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.774 0.226
E74.2 Disorders of galactose metabolism
0.000 0.774 0.226
E74.1 Disorders of fructose metabolism
0.000 0.774 0.226
E74.0 Glycogen storage disease
0.000 0.774 0.226
E84.9 Cystic fibrosis, unspecified
0.000 0.775 0.225
E14.9 Without complications
0.000 0.775 0.225
E24.8 Other Cushing's syndrome
0.000 0.780 0.220
E66.8 Other obesity
0.000 0.781 0.219

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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