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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263509
log Bayes Factor = 26.1338
Chromosome 6   position 31,066,419  (GRCh37) Explore rs9263509 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.009 0.991
E00-E07 Disorders of thyroid gland
0.001 0.013 0.986
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.013 0.987
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.015 0.985
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.016 0.984
E16 Other disorders of pancreatic internal secretion
0.000 0.017 0.983
E16.2 Hypoglycaemia, unspecified
0.000 0.019 0.981
G35 Multiple sclerosis
0.000 0.021 0.979
E10.1 With ketoacidosis
0.000 0.027 0.973
M45.X9 Ankylosing spondylitis (Site unspecified)
0.973 0.027 0.000
E03.9 Hypothyroidism, unspecified
0.951 0.049 0.000
L40.9 Psoriasis, unspecified
0.000 0.062 0.938
E10.2 With renal complications
0.000 0.065 0.935
L40 Psoriasis
0.000 0.068 0.932
L40.5 Arthropathic psoriasis
0.000 0.073 0.927
E06 Thyroiditis
0.000 0.085 0.915
E10.9 Without complications
0.000 0.109 0.891
M45 Ankylosing spondylitis
0.877 0.123 0.000
E06.9 Thyroiditis, unspecified
0.000 0.163 0.837
L40.0 Psoriasis vulgaris
0.000 0.168 0.832
E03 Other hypothyroidism
0.663 0.184 0.153
E65-E68 Obesity and other hyperalimentation
0.000 0.189 0.811
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.798 0.202 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.221 0.779
E10.8 With unspecified complications
0.000 0.223 0.777
E10.5 With peripheral circulatory complications
0.000 0.229 0.771
E05.8 Other thyrotoxicosis
0.000 0.233 0.767
E16.1 Other hypoglycaemia
0.000 0.235 0.765
E13 Other specified diabetes mellitus
0.000 0.237 0.763
M45.X2 Ankylosing spondylitis (Cervical region)
0.761 0.239 0.000
E06.3 Autoimmune thyroiditis
0.000 0.255 0.745
M45.X6 Ankylosing spondylitis (Lumbar region)
0.735 0.265 0.000
E10.4 With neurological complications
0.000 0.277 0.723
E10.6 With other specified complications
0.000 0.278 0.722
E10.7 With multiple complications
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.292 0.707
E00 Congenital iodine-deficiency syndrome
0.001 0.292 0.707
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.292 0.707
E15 Nondiabetic hypoglycaemic coma
0.000 0.293 0.707
E05.5 Thyroid crisis or storm
0.000 0.294 0.706
E05.4 Thyrotoxicosis factitia
0.000 0.294 0.706
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.294 0.706
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.294 0.706
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.295 0.705
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.295 0.705
E16.4 Abnormal secretion of gastrin
0.000 0.295 0.705
E16.3 Increased secretion of glucagon
0.000 0.295 0.705
E10.0 With coma
0.000 0.306 0.694
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.312 0.687
E50-E64 Other nutritional deficiencies
0.000 0.315 0.684
L40.4 Guttate psoriasis
0.000 0.332 0.668
L40.3 Pustulosis palmaris et plantaris
0.000 0.332 0.668
L40.2 Acrodermatitis continua
0.000 0.332 0.668
L40.1 Generalised pustular psoriasis
0.000 0.333 0.667
E65 Localised adiposity
0.000 0.334 0.666
E06.5 Other chronic thyroiditis
0.000 0.344 0.656
E06.4 Drug-induced thyroiditis
0.000 0.344 0.656
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.344 0.656
E06.1 Subacute thyroiditis
0.000 0.344 0.656
E06.0 Acute thyroiditis
0.000 0.344 0.656
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.346 0.654
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.629 0.371 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.629 0.371 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.629 0.371 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.629 0.371 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.629 0.371 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.629 0.371 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.371 0.628
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.538 0.378 0.085
E40-E46 Malnutrition
0.000 0.383 0.617
E66 Obesity
0.000 0.392 0.608
E13.9 Without complications
0.000 0.401 0.599
E03.8 Other specified hypothyroidism
0.512 0.404 0.084
E55 Vitamin D deficiency
0.000 0.405 0.595
E11 Non-insulin-dependent diabetes mellitus
0.000 0.406 0.594
L40.8 Other psoriasis
0.000 0.408 0.592
E03.5 Myxoedema coma
0.476 0.415 0.110
E03.4 Atrophy of thyroid (acquired)
0.476 0.415 0.110
E03.3 Postinfectious hypothyroidism
0.476 0.415 0.110
E03.1 Congenital hypothyroidism without goitre
0.476 0.415 0.110
E03.0 Congenital hypothyroidism with diffuse goitre
0.476 0.415 0.110
E67 Other hyperalimentation
0.000 0.418 0.582
E68 Sequelae of hyperalimentation
0.000 0.418 0.582
E05.9 Thyrotoxicosis, unspecified
0.000 0.444 0.556
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.445 0.555
E66.8 Other obesity
0.000 0.450 0.550
E13.8 With unspecified complications
0.000 0.453 0.547
E13.7 With multiple complications
0.000 0.453 0.547
E13.6 With other specified complications
0.000 0.453 0.547
E13.5 With peripheral circulatory complications
0.000 0.453 0.547
E13.4 With neurological complications
0.000 0.453 0.547
E13.3 With ophthalmic complications
0.000 0.453 0.547
E13.2 With renal complications
0.000 0.453 0.547
E13.1 With ketoacidosis
0.000 0.453 0.547
E13.0 With coma
0.000 0.453 0.547
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.463 0.537
E55.9 Vitamin D deficiency, unspecified
0.000 0.469 0.531
K90 Intestinal malabsorption
0.000 0.474 0.526
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.001 0.492 0.507
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.001 0.492 0.507
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.001 0.492 0.507
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.001 0.492 0.507
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.492 0.507
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.001 0.492 0.507
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.001 0.492 0.507
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.001 0.492 0.507
E11.3 With ophthalmic complications
0.000 0.496 0.504
G36 Other acute disseminated demyelination
0.000 0.507 0.493
E11.6 With other specified complications
0.000 0.507 0.492
E70-E90 Metabolic disorders
0.000 0.508 0.492
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.509 0.491
E63 Other nutritional deficiencies
0.000 0.509 0.491
E51 Thiamine deficiency
0.000 0.509 0.491
E50 Vitamin A deficiency
0.000 0.509 0.491
E60 Dietary zinc deficiency
0.000 0.509 0.491
E59 Dietary selenium deficiency
0.000 0.509 0.491
E58 Dietary calcium deficiency
0.000 0.509 0.491
E54 Ascorbic acid deficiency
0.000 0.509 0.491
E52 Niacin deficiency [pellagra]
0.000 0.509 0.491
E83 Disorders of mineral metabolism
0.000 0.519 0.481
E07 Other disorders of thyroid
0.002 0.523 0.476
E83.1 Disorders of iron metabolism
0.000 0.524 0.476
E11.4 With neurological complications
0.000 0.528 0.472
E66.0 Obesity due to excess calories
0.000 0.538 0.462
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.538 0.462
G37.5 Concentric sclerosis [Balo]
0.000 0.549 0.451
G37.4 Subacute necrotising myelitis
0.000 0.549 0.451
G37.2 Central pontine myelinolysis
0.000 0.549 0.451
G37.1 Central demyelination of corpus callosum
0.000 0.549 0.451
G37.0 Diffuse sclerosis
0.000 0.549 0.451
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.558 0.442
E45 Retarded development following protein-energy malnutrition
0.000 0.558 0.442
E43 Unspecified severe protein-energy malnutrition
0.000 0.558 0.442
E42 Marasmic kwashiorkor
0.000 0.558 0.442
E41 Nutritional marasmus
0.000 0.558 0.442
E40 Kwashiorkor
0.000 0.558 0.442
E11.2 With renal complications
0.000 0.558 0.442
E56 Other vitamin deficiencies
0.000 0.558 0.441
E61 Deficiency of other nutrient elements
0.000 0.561 0.439
E66.1 Drug-induced obesity
0.000 0.564 0.436
E83.5 Disorders of calcium metabolism
0.000 0.564 0.436
E11.8 With unspecified complications
0.000 0.565 0.435
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.570 0.430
E55.0 Rickets, active
0.000 0.573 0.427
E11.7 With multiple complications
0.000 0.574 0.426
L40-L45 Papulosquamous disorders
0.000 0.580 0.420
E67.8 Other specified hyperalimentation
0.000 0.583 0.417
E67.3 Hypervitaminosis D
0.000 0.583 0.417
E67.2 Megavitamin-B6 syndrome
0.000 0.583 0.417
E67.1 Hypercarotenaemia
0.000 0.583 0.417
E67.0 Hypervitaminosis A
0.000 0.583 0.417
E85 Amyloidosis
0.000 0.585 0.415
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.589 0.411
E11.1 With ketoacidosis
0.000 0.599 0.401
K90.9 Intestinal malabsorption, unspecified
0.000 0.606 0.394
E53 Deficiency of other B group vitamins
0.000 0.615 0.385
E14 Unspecified diabetes mellitus
0.000 0.616 0.384
K90.3 Pancreatic steatorrhoea
0.000 0.623 0.377
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.623 0.377
K90.1 Tropical sprue
0.000 0.623 0.377
K90.8 Other intestinal malabsorption
0.000 0.624 0.376
E85.4 Organ-limited amyloidosis
0.000 0.641 0.359
G36.9 Acute disseminated demyelination, unspecified
0.000 0.646 0.353
G36.8 Other specified acute disseminated demyelination
0.000 0.646 0.353
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.646 0.353
G36.0 Neuromyelitis optica [Devic]
0.000 0.646 0.353
E07.8 Other specified disorders of thyroid
0.001 0.646 0.352
E84 Cystic fibrosis
0.000 0.647 0.353
E79 Disorders of purine and pyrimidine metabolism
0.000 0.647 0.353
E77 Disorders of glycoprotein metabolism
0.000 0.647 0.353
E76 Disorders of glycosaminoglycan metabolism
0.000 0.647 0.353
E72 Other disorders of amino-acid metabolism
0.000 0.647 0.353
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.647 0.353
E70 Disorders of aromatic amino-acid metabolism
0.000 0.647 0.353
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.647 0.353
E50.9 Vitamin A deficiency, unspecified
0.000 0.648 0.352
E50.8 Other manifestations of vitamin A deficiency
0.000 0.648 0.352
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.648 0.352
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.648 0.352
E50.5 Vitamin A deficiency with night blindness
0.000 0.648 0.352
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.648 0.352
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.648 0.352
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.648 0.352
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.648 0.352
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.648 0.352
E51.9 Thiamine deficiency, unspecified
0.000 0.648 0.352
E51.8 Other manifestations of thiamine deficiency
0.000 0.648 0.352
E51.2 Wernicke's encephalopathy
0.000 0.648 0.352
E51.1 Beriberi
0.000 0.648 0.352
E63.9 Nutritional deficiency, unspecified
0.000 0.648 0.352
E63.8 Other specified nutritional deficiencies
0.000 0.648 0.352
E63.1 Imbalance of constituents of food intake
0.000 0.648 0.352
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.648 0.352
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.648 0.352
E64.8 Sequelae of other nutritional deficiencies
0.000 0.648 0.352
E64.3 Sequelae of rickets
0.000 0.648 0.352
E64.2 Sequelae of vitamin C deficiency
0.000 0.648 0.352
E64.1 Sequelae of vitamin A deficiency
0.000 0.648 0.352
E64.0 Sequelae of protein-energy malnutrition
0.000 0.648 0.352
E11.5 With peripheral circulatory complications
0.000 0.651 0.349
E46 Unspecified protein-energy malnutrition
0.000 0.652 0.348
E11.0 With coma
0.000 0.653 0.347
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.655 0.345
E83.8 Other disorders of mineral metabolism
0.000 0.655 0.345
E83.2 Disorders of zinc metabolism
0.000 0.655 0.345
E83.0 Disorders of copper metabolism
0.000 0.655 0.345
E74 Other disorders of carbohydrate metabolism
0.000 0.656 0.344
E07.1 Dyshormogenetic goitre
0.001 0.658 0.341
E07.0 Hypersecretion of calcitonin
0.001 0.658 0.341
E88 Other metabolic disorders
0.000 0.665 0.334
L42 Pityriasis rosea
0.000 0.666 0.334
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.667 0.332
E86 Volume depletion
0.000 0.671 0.329
E73 Lactose intolerance
0.000 0.681 0.319
E44.1 Mild protein-energy malnutrition
0.000 0.683 0.317
E44.0 Moderate protein-energy malnutrition
0.000 0.683 0.317
E56.9 Vitamin deficiency, unspecified
0.000 0.683 0.317
E56.8 Deficiency of other vitamins
0.000 0.683 0.317
E56.0 Deficiency of vitamin E
0.000 0.683 0.317
E61.9 Deficiency of nutrient element, unspecified
0.000 0.685 0.315
E61.8 Deficiency of other specified nutrient elements
0.000 0.685 0.315
E61.7 Deficiency of multiple nutrient elements
0.000 0.685 0.315
E61.6 Vanadium deficiency
0.000 0.685 0.315
E61.5 Molybdenum deficiency
0.000 0.685 0.315
E61.4 Chromium deficiency
0.000 0.685 0.315
E61.3 Manganese deficiency
0.000 0.685 0.315
E61.0 Copper deficiency
0.000 0.685 0.315
E61.2 Magnesium deficiency
0.000 0.686 0.314
L44 Other papulosquamous disorders
0.000 0.698 0.301
L41 Parapsoriasis
0.000 0.698 0.301
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.698 0.301
E53.9 Vitamin B deficiency, unspecified
0.000 0.700 0.300
E85.9 Amyloidosis, unspecified
0.000 0.701 0.299
E85.8 Other amyloidosis
0.000 0.702 0.298
E85.3 Secondary systemic amyloidosis
0.000 0.702 0.298
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.702 0.298
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.702 0.298
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.702 0.298
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.703 0.297
E14.4 With neurological complications
0.000 0.704 0.296
E14.1 With ketoacidosis
0.000 0.714 0.286
L43 Lichen planus
0.000 0.723 0.277
E53.1 Pyridoxine deficiency
0.000 0.724 0.276
E53.0 Riboflavin deficiency
0.000 0.724 0.276
E14.8 With unspecified complications
0.000 0.724 0.275
E14.7 With multiple complications
0.000 0.724 0.275
E14.2 Withrenal complications
0.000 0.724 0.275
E14.0 With coma
0.000 0.724 0.275
E56.1 Deficiency of vitamin K
0.000 0.732 0.267
E61.1 Iron deficiency
0.000 0.736 0.264
E14.6 With other specified complications
0.000 0.744 0.256
E04 Other non-toxic goitre
0.000 0.744 0.256
E88.2 Lipomatosis, not elsewhere classified
0.000 0.745 0.255
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.747 0.253
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.747 0.253
E70.3 Albinism
0.000 0.747 0.253
E70.2 Disorders of tyrosine metabolism
0.000 0.747 0.253
E70.1 Other hyperphenylalaninaemias
0.000 0.747 0.253
E70.0 Classical phenylketonuria
0.000 0.747 0.253
E71.3 Disorders of fatty-acid metabolism
0.000 0.747 0.253
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.747 0.253
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.747 0.253
E71.0 Maple-syrup-urine disease
0.000 0.747 0.253
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.747 0.253
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.747 0.253
E72.5 Disorders of glycine metabolism
0.000 0.747 0.253
E72.4 Disorders of ornithine metabolism
0.000 0.747 0.253
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.747 0.253
E72.2 Disorders of urea cycle metabolism
0.000 0.747 0.253
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.747 0.253
E72.0 Disorders of amino-acid transport
0.000 0.747 0.253
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.747 0.253
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.747 0.253
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.747 0.253
E76.2 Other mucopolysaccharidoses
0.000 0.747 0.253
E76.1 Mucopolysaccharidosis, type II
0.000 0.747 0.253
E76.0 Mucopolysaccharidosis, type I
0.000 0.747 0.253
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.747 0.253
E77.8 Other disorders of glycoprotein metabolism
0.000 0.747 0.253
E77.1 Defects in glycoprotein degradation
0.000 0.747 0.253
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.747 0.253
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.747 0.253
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.747 0.253
E79.1 Lesch-Nyhan syndrome
0.000 0.747 0.253
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.747 0.253
E84.9 Cystic fibrosis, unspecified
0.000 0.747 0.253
E84.8 Cystic fibrosis with other manifestations
0.000 0.747 0.253
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.747 0.253
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.747 0.253
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.750 0.250
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.753 0.247
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.753 0.247
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.753 0.247
E74.2 Disorders of galactose metabolism
0.000 0.753 0.247
E74.1 Disorders of fructose metabolism
0.000 0.753 0.247
E74.0 Glycogen storage disease
0.000 0.753 0.247
E14.3 With ophthalmic complications
0.000 0.753 0.247
E14.5 With peripheral circulatory complications
0.000 0.760 0.240
E88.9 Metabolic disorder, unspecified
0.000 0.760 0.240
E75.6 Lipid storage disorder, unspecified
0.000 0.761 0.238
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.761 0.238
E75.3 Sphingolipidosis, unspecified
0.000 0.761 0.238
E75.2 Other sphingolipidosis
0.000 0.761 0.238
E75.1 Other gangliosidosis
0.000 0.761 0.238
E75.0 GM2 gangliosidosis
0.000 0.761 0.238
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.761 0.238
E89.2 Postprocedural hypoparathyroidism
0.000 0.765 0.235
E20-E35 Disorders of other endocrine glands
0.000 0.767 0.232
E73.8 Other lactose intolerance
0.000 0.771 0.229
E73.1 Secondary lactase deficiency
0.000 0.771 0.229
E73.0 Congenital lactase deficiency
0.000 0.771 0.229
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.773 0.226
L43.8 Other lichen planus
0.000 0.775 0.224
E88.8 Other specified metabolic disorders
0.000 0.777 0.223
E88.3 Tumour lysis syndrome
0.000 0.777 0.223
E83.4 Disorders of magnesium metabolism
0.000 0.778 0.222
E75.5 Other lipid storage disorders
0.000 0.781 0.218
L41.9 Parapsoriasis, unspecified
0.000 0.784 0.216
L41.8 Other parapsoriasis
0.000 0.784 0.216
L41.5 Retiform parapsoriasis
0.000 0.784 0.216
L41.4 Large plaque parapsoriasis
0.000 0.784 0.216
L41.3 Small plaque parapsoriasis
0.000 0.784 0.216
L41.2 Lymphomatoid papulosis
0.000 0.784 0.216
L41.1 Pityriasis lichenoides chronica
0.000 0.784 0.216
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.784 0.216
L44.9 Papulosquamous disorder, unspecified
0.000 0.784 0.216
L44.8 Other specified papulosquamous disorders
0.000 0.784 0.216
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.784 0.216
L44.3 Lichen ruber moniliformis
0.000 0.784 0.216
L44.2 Lichen striatus
0.000 0.784 0.216
L44.1 Lichen nitidus
0.000 0.784 0.216
L44.0 Pityriasis rubra pilaris
0.000 0.784 0.216
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.787 0.213
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.787 0.213
E89.5 Postprocedural testicular hypofunction
0.000 0.787 0.213
E89.1 Postprocedural hypoinsulinaemia
0.000 0.787 0.213
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.796 0.203
E83.3 Disorders of phosphorus metabolism
0.000 0.799 0.201
L43.3 Subacute (active) lichen planus
0.000 0.801 0.199
L43.2 Lichenoid drug reaction
0.000 0.801 0.199
L43.1 Bullous lichen planus
0.000 0.801 0.199
L43.0 Hypertrophic lichen planus
0.000 0.801 0.199
E89.0 Postprocedural hypothyroidism
0.000 0.804 0.196
E89.4 Postprocedural ovarian failure
0.000 0.805 0.195
E73.9 Lactose intolerance, unspecified
0.000 0.805 0.195
E04.0 Non-toxic diffuse goitre
0.000 0.813 0.187
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.816 0.184
E04.8 Other specified non-toxic goitre
0.000 0.816 0.183
E89.3 Postprocedural hypopituitarism
0.000 0.818 0.182
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.820 0.180
E22 Hyperfunction of pituitary gland
0.000 0.832 0.168
E27 Other disorders of adrenal gland
0.000 0.832 0.168
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.833 0.167
E32 Diseases of thymus
0.000 0.833 0.167
E31 Polyglandular dysfunction
0.000 0.833 0.167
E30 Disorders of puberty, not elsewhere classified
0.000 0.833 0.167
E25 Adrenogenital disorders
0.000 0.833 0.167
E04.9 Non-toxic goitre, unspecified
0.000 0.836 0.164
E20 Hypoparathyroidism
0.000 0.838 0.162
E34 Other endocrine disorders
0.000 0.842 0.158
E21.0 Primary hyperparathyroidism
0.000 0.842 0.158
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.850 0.150
E27.1 Primary adrenocortical insufficiency
0.000 0.851 0.149
E29 Testicular dysfunction
0.000 0.853 0.147
E26 Hyperaldosteronism
0.001 0.855 0.144
E22.1 Hyperprolactinaemia
0.000 0.859 0.141
E24 Cushing's syndrome
0.000 0.861 0.139
E23 Hypofunction and other disorders of pituitary gland
0.000 0.862 0.137
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.868 0.132
E80.5 Crigler-Najjar syndrome
0.000 0.868 0.132
E80.3 Defects of catalase and peroxydase
0.000 0.868 0.132
E80.1 Porphyria cutanea tarda
0.000 0.868 0.132
E80.0 Hereditary erythropoietic porphyria
0.000 0.868 0.132
E21.4 Other specified disorders of parathyroid gland
0.000 0.870 0.129
E21.2 Other hyperparathyroidism
0.000 0.870 0.129
E34.0 Carcinoid syndrome
0.000 0.874 0.125
E22.0 Acromegaly and pituitary gigantism
0.000 0.874 0.125
L43.9 Lichen planus, unspecified
0.000 0.876 0.124
E27.8 Other specified disorders of adrenal gland
0.000 0.877 0.123
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.879 0.121
E22.8 Other hyperfunction of pituitary gland
0.000 0.879 0.121
E27.5 Adrenomedullary hyperfunction
0.000 0.879 0.120
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.879 0.120
E27.0 Other adrenocortical overactivity
0.000 0.879 0.120
E25.9 Adrenogenital disorder, unspecified
0.000 0.880 0.120
E25.8 Other adrenogenital disorders
0.000 0.880 0.120
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.880 0.120
E30.9 Disorder of puberty, unspecified
0.000 0.880 0.120
E30.8 Other disorders of puberty
0.000 0.880 0.120
E30.1 Precocious puberty
0.000 0.880 0.120
E30.0 Delayed puberty
0.000 0.880 0.120
E31.9 Polyglandular dysfunction, unspecified
0.000 0.880 0.120
E31.8 Other polyglandular dysfunction
0.000 0.880 0.120
E31.1 Polyglandular hyperfunction
0.000 0.880 0.120
E31.0 Autoimmune polyglandular failure
0.000 0.880 0.120
E32.9 Disease of thymus, unspecified
0.000 0.880 0.120
E32.8 Other diseases of thymus
0.000 0.880 0.120
E32.1 Abscess of thymus
0.000 0.880 0.120
E32.0 Persistent hyperplasia of thymus
0.000 0.880 0.120
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.880 0.120
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.880 0.120
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.880 0.120
E80.6 Other disorders of bilirubin metabolism
0.000 0.883 0.117
E20.8 Other hypoparathyroidism
0.000 0.883 0.116
E20.1 Pseudohypoparathyroidism
0.000 0.883 0.116
E20.0 Idiopathic hypoparathyroidism
0.000 0.883 0.116
E80.2 Other porphyria
0.001 0.885 0.115
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.886 0.114
E23.6 Other disorders of pituitary gland
0.000 0.886 0.113
E34.5 Androgen resistance syndrome
0.000 0.886 0.113
E34.4 Constitutional tall stature
0.000 0.886 0.113
E34.3 Short stature, not elsewhere classified
0.000 0.886 0.113
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.886 0.113
E34.1 Other hypersecretion of intestinal hormones
0.000 0.886 0.113
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.887 0.113
E34.9 Endocrine disorder, unspecified
0.000 0.887 0.112
E20.9 Hypoparathyroidism, unspecified
0.000 0.888 0.111
E27.9 Disorder of adrenal gland, unspecified
0.000 0.890 0.110
E53.8 Deficiency of other specified B group vitamins
0.000 0.890 0.110
E23.7 Disorder of pituitary gland, unspecified
0.000 0.890 0.109
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.892 0.108
E29.9 Testicular dysfunction, unspecified
0.000 0.894 0.105
E29.8 Other testicular dysfunction
0.000 0.894 0.105
E29.0 Testicular hyperfunction
0.000 0.894 0.105
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.895 0.105
E26.9 Hyperaldosteronism, unspecified
0.001 0.896 0.104
E26.8 Other hyperaldosteronism
0.001 0.896 0.104
E26.1 Secondary hyperaldosteronism
0.001 0.896 0.104
E24.8 Other Cushing's syndrome
0.000 0.900 0.100
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.900 0.100
E24.3 Ectopic ACTH syndrome
0.000 0.900 0.100
E24.1 Nelson's syndrome
0.000 0.900 0.100
E24.0 Pituitary-dependent Cushing's disease
0.000 0.900 0.100
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.901 0.098
E23.1 Drug-induced hypopituitarism
0.000 0.901 0.098
E27.2 Addisonian crisis
0.000 0.908 0.091
E04.2 Non-toxic multinodular goitre
0.000 0.910 0.090
E24.2 Drug-induced Cushing's syndrome
0.001 0.910 0.090
E34.8 Other specified endocrine disorders
0.001 0.914 0.086
E29.1 Testicular hypofunction
0.000 0.914 0.086
E24.9 Cushing's syndrome, unspecified
0.001 0.915 0.085
E14.9 Without complications
0.000 0.917 0.083
E87.5 Hyperkalaemia
0.000 0.917 0.083
E26.0 Primary hyperaldosteronism
0.001 0.918 0.081
E07.9 Disorder of thyroid, unspecified
0.003 0.922 0.075
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.922 0.077
M45-M49 Spondylopathies
0.077 0.923 0.000
E87.2 Acidosis
0.000 0.923 0.077
E87.4 Mixed disorder of acid-base balance
0.000 0.925 0.075
E87.6 Hypokalaemia
0.000 0.925 0.075
E87.7 Fluid overload
0.000 0.925 0.075
E28 Ovarian dysfunction
0.004 0.926 0.070
E21.3 Hyperparathyroidism, unspecified
0.000 0.928 0.071
E23.0 Hypopituitarism
0.000 0.931 0.069
E87.3 Alkalosis
0.000 0.932 0.068
E04.1 Non-toxic single thyroid nodule
0.000 0.933 0.067
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.939 0.061
M13.9 Arthritis, unspecified
0.000 0.941 0.059
M06.9 Rheumatoid arthritis, unspecified
0.056 0.944 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.945 0.055
E80.4 Gilbert's syndrome
0.001 0.945 0.054
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.054 0.946 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.946 0.054
E28.9 Ovarian dysfunction, unspecified
0.003 0.946 0.051
E28.8 Other ovarian dysfunction
0.003 0.946 0.051
E28.1 Androgen excess
0.003 0.946 0.051
E28.0 Oestrogen excess
0.003 0.946 0.051
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.947 0.053
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.052 0.948 0.000
M06 Other rheumatoid arthritis
0.051 0.949 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.949 0.051
M49 Spondylopathies in diseases classified elsewhere
0.051 0.949 0.000
M46 Other inflammatory spondylopathies
0.051 0.949 0.000
E23.2 Diabetes insipidus
0.001 0.950 0.049
M06.0 Seronegative rheumatoid arthritis
0.050 0.950 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.048 0.952 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.952 0.048
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.047 0.953 0.000
M13.94 Arthritis, unspecified (Hand)
0.000 0.953 0.047
M25.5 Pain in joint
0.000 0.953 0.047
E78.6 Lipoprotein deficiency
0.000 0.953 0.046
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.045 0.955 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.955 0.045
M06.3 Rheumatoid nodule
0.044 0.956 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.044 0.956 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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