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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9263872
log Bayes Factor = 61.8516
Chromosome 6   position 31,170,608  (GRCh37) Explore rs9263872 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
D86 Sarcoidosis
0.000 0.003 0.997
L40 Psoriasis
0.000 0.007 0.993
D60-D64 Aplastic and other anaemias
0.000 0.007 0.993
R31 Unspecified haematuria
0.992 0.008 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.008 0.992
D64 Other anaemias
0.000 0.011 0.989
D64.9 Anaemia, unspecified
0.000 0.016 0.984
L40.5 Arthropathic psoriasis
0.000 0.016 0.984
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.030 0.970
D69 Purpura and other haemorrhagic conditions
0.000 0.038 0.962
D50-D53 Nutritional anaemias
0.000 0.043 0.957
D69.6 Thrombocytopenia, unspecified
0.000 0.045 0.955
D86.3 Sarcoidosis of skin
0.000 0.072 0.928
D80 Immunodeficiency with predominantly antibody defects
0.000 0.075 0.925
D50 Iron deficiency anaemia
0.000 0.102 0.898
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.102 0.898
D50.9 Iron deficiency anaemia, unspecified
0.000 0.110 0.890
L40.0 Psoriasis vulgaris
0.000 0.122 0.878
E03 Other hypothyroidism
0.000 0.123 0.877
D70 Agranulocytosis
0.000 0.136 0.864
D55-D59 Haemolytic anaemias
0.000 0.149 0.851
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.151 0.849
D62 Acute posthaemorrhagic anaemia
0.000 0.157 0.843
D66 Hereditary factor VIII deficiency
0.000 0.162 0.838
D69.4 Other primary thrombocytopenia
0.000 0.174 0.826
D69.2 Other nonthrombocytopenic purpura
0.000 0.175 0.825
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.176 0.824
D64.8 Other specified anaemias
0.000 0.184 0.816
L40.1 Generalised pustular psoriasis
0.000 0.191 0.809
D69.5 Secondary thrombocytopenia
0.000 0.192 0.808
D51 Vitamin B12 deficiency anaemia
0.000 0.207 0.793
D61 Other aplastic anaemias
0.000 0.208 0.792
D52 Folate deficiency anaemia
0.000 0.212 0.788
D84 Other immunodeficiencies
0.000 0.214 0.786
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.216 0.784
D72 Other disorders of white blood cells
0.000 0.223 0.777
D86.0 Sarcoidosis of lung
0.000 0.228 0.772
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.231 0.769
L40.8 Other psoriasis
0.000 0.232 0.768
E00-E07 Disorders of thyroid gland
0.000 0.240 0.760
D83 Common variable immunodeficiency
0.000 0.246 0.754
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.252 0.748
L40.3 Pustulosis palmaris et plantaris
0.000 0.260 0.740
E05.9 Thyrotoxicosis, unspecified
0.000 0.269 0.731
D59 Acquired haemolytic anaemia
0.000 0.271 0.729
L40.4 Guttate psoriasis
0.000 0.276 0.724
D58 Other hereditary haemolytic anaemias
0.000 0.281 0.719
D81 Combined immunodeficiencies
0.000 0.284 0.716
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.287 0.713
L40.2 Acrodermatitis continua
0.000 0.288 0.712
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.288 0.712
D64.4 Congenital dyserythropoietic anaemia
0.000 0.291 0.709
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.291 0.709
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.291 0.709
D64.0 Hereditary sideroblastic anaemia
0.000 0.291 0.709
D64.3 Other sideroblastic anaemias
0.000 0.297 0.703
D86.1 Sarcoidosis of lymph nodes
0.000 0.297 0.703
D69.8 Other specified haemorrhagic conditions
0.000 0.310 0.690
E03.8 Other specified hypothyroidism
0.000 0.318 0.682
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.327 0.673
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.327 0.672
D52.9 Folate deficiency anaemia, unspecified
0.000 0.332 0.668
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.333 0.667
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.335 0.665
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.337 0.663
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.337 0.663
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.337 0.663
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.337 0.663
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.337 0.663
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.337 0.663
D58.0 Hereditary spherocytosis
0.000 0.344 0.656
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.344 0.656
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.350 0.650
D61.9 Aplastic anaemia, unspecified
0.000 0.351 0.649
D67 Hereditary factor IX deficiency
0.000 0.355 0.645
D50.1 Sideropenic dysphagia
0.000 0.356 0.644
D74 Methaemoglobinaemia
0.000 0.356 0.644
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.356 0.644
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.356 0.644
D72.1 Eosinophilia
0.000 0.360 0.640
D59.1 Other autoimmune haemolytic anaemias
0.000 0.360 0.640
D72.8 Other specified disorders of white blood cells
0.000 0.361 0.639
D84.9 Immunodeficiency, unspecified
0.000 0.361 0.639
D69.1 Qualitative platelet defects
0.000 0.366 0.634
D82 Immunodeficiency associated with other major defects
0.000 0.371 0.629
E03.5 Myxoedema coma
0.000 0.371 0.629
E03.4 Atrophy of thyroid (acquired)
0.000 0.371 0.629
E03.3 Postinfectious hypothyroidism
0.000 0.371 0.629
D84.1 Defects in the complement system
0.000 0.373 0.627
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.373 0.627
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.375 0.625
E03.1 Congenital hypothyroidism without goitre
0.000 0.382 0.618
D57 Sickle-cell disorders
0.000 0.390 0.610
D55 Anaemia due to enzyme disorders
0.000 0.390 0.610
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.395 0.605
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.409 0.591
D89.3 Immune reconstitution syndrome
0.000 0.409 0.591
D61.0 Constitutional aplastic anaemia
0.000 0.413 0.587
D53 Other nutritional anaemias
0.000 0.416 0.584
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.417 0.583
D83.9 Common variable immunodeficiency, unspecified
0.000 0.421 0.579
D76.3 Other histiocytosis syndromes
0.000 0.421 0.579
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.573
D51.2 Transcobalamin II deficiency
0.000 0.431 0.569
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.431 0.569
D61.8 Other specified aplastic anaemias
0.000 0.432 0.568
D61.3 Idiopathic aplastic anaemia
0.000 0.432 0.568
D61.2 Aplastic anaemia due to other external agents
0.000 0.432 0.568
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.433 0.567
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.434 0.566
D52.8 Other folate deficiency anaemias
0.000 0.435 0.565
D52.1 Drug-induced folate deficiency anaemia
0.000 0.435 0.565
D52.0 Dietary folate deficiency anaemia
0.000 0.435 0.565
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.436 0.564
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.437 0.563
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.440 0.560
D72.9 Disorder of white blood cells, unspecified
0.000 0.443 0.557
D72.0 Genetic anomalies of leukocytes
0.000 0.443 0.557
K90 Intestinal malabsorption
0.000 0.447 0.553
D69.0 Allergic purpura
0.000 0.451 0.548
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.452 0.548
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.455 0.545
E00 Congenital iodine-deficiency syndrome
0.000 0.455 0.545
D61.1 Drug-induced aplastic anaemia
0.000 0.456 0.544
D83.8 Other common variable immunodeficiencies
0.000 0.459 0.541
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.459 0.541
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.459 0.541
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.459 0.541
E05.5 Thyroid crisis or storm
0.000 0.464 0.536
E05.4 Thyrotoxicosis factitia
0.000 0.464 0.536
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.464 0.536
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.464 0.536
D59.8 Other acquired haemolytic anaemias
0.000 0.477 0.522
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.477 0.522
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.477 0.522
D59.3 Haemolytic-uraemic syndrome
0.000 0.477 0.522
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.477 0.522
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.477 0.522
D86.8 Sarcoidosis of other and combined sites
0.000 0.479 0.520
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.484 0.515
D58.1 Hereditary elliptocytosis
0.000 0.484 0.515
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.513
D81.8 Other combined immunodeficiencies
0.000 0.486 0.513
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.513
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.513
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.513
D81.4 Nezelof's syndrome
0.000 0.486 0.513
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.513
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.513
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.513
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.513
E04 Other non-toxic goitre
0.000 0.487 0.513
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.489 0.511
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.489 0.511
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.489 0.511
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.495 0.505
D89.1 Cryoglobulinaemia
0.000 0.507 0.493
D58.2 Other haemoglobinopathies
0.000 0.515 0.485
D60.8 Other acquired pure red cell aplasias
0.000 0.518 0.482
D60.1 Transient acquired pure red cell aplasia
0.000 0.518 0.482
D60.0 Chronic acquired pure red cell aplasia
0.000 0.518 0.482
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.525 0.475
D56 Thalassaemia
0.000 0.529 0.470
E04.0 Non-toxic diffuse goitre
0.000 0.533 0.467
E07 Other disorders of thyroid
0.000 0.535 0.465
D74.9 Methaemoglobinaemia, unspecified
0.000 0.538 0.462
D74.8 Other methaemoglobinaemias
0.000 0.538 0.462
D74.0 Congenital methaemoglobinaemia
0.000 0.538 0.462
D84.8 Other specified immunodeficiencies
0.000 0.538 0.461
K90.9 Intestinal malabsorption, unspecified
0.000 0.544 0.455
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.549 0.451
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.549 0.451
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.549 0.451
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.549 0.451
D82.2 Immunodeficiency with short-limbed stature
0.000 0.549 0.451
D82.0 Wiskott-Aldrich syndrome
0.000 0.549 0.451
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.549 0.450
D69.9 Haemorrhagic condition, unspecified
0.001 0.555 0.444
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.557 0.443
E06 Thyroiditis
0.000 0.560 0.440
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.561 0.439
K75 Other inflammatory liver diseases
0.000 0.562 0.438
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.562 0.437
D55.8 Other anaemias due to enzyme disorders
0.000 0.562 0.437
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.562 0.437
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.562 0.437
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.562 0.437
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.562 0.437
D57.8 Other sickle-cell disorders
0.000 0.562 0.437
D57.3 Sickle-cell trait
0.000 0.562 0.437
D57.2 Double heterozygous sickling disorders
0.000 0.562 0.437
D57.1 Sickle-cell anaemia without crisis
0.000 0.562 0.437
D57.0 Sickle-cell anaemia with crisis
0.000 0.562 0.437
K75.4 Autoimmune hepatitis
0.000 0.568 0.432
K70-K77 Diseases of liver
0.000 0.569 0.431
K75.8 Other specified inflammatory liver diseases
0.000 0.572 0.428
K73 Chronic hepatitis, not elsewhere classified
0.000 0.576 0.424
K70 Alcoholic liver disease
0.000 0.580 0.420
D53.8 Other specified nutritional anaemias
0.000 0.581 0.419
D53.2 Scorbutic anaemia
0.000 0.581 0.419
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.581 0.419
D53.0 Protein deficiency anaemia
0.000 0.581 0.419
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.595 0.405
D50.8 Other iron deficiency anaemias
0.000 0.602 0.398
K90.3 Pancreatic steatorrhoea
0.000 0.603 0.397
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.603 0.397
K90.1 Tropical sprue
0.000 0.603 0.397
E07.8 Other specified disorders of thyroid
0.000 0.608 0.392
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.609 0.391
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.609 0.391
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.609 0.391
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.609 0.391
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.609 0.391
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.609 0.391
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.609 0.391
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.609 0.391
K73.9 Chronic hepatitis, unspecified
0.000 0.612 0.388
K70.9 Alcoholic liver disease, unspecified
0.000 0.620 0.380
E06.3 Autoimmune thyroiditis
0.000 0.622 0.378
K70.1 Alcoholic hepatitis
0.000 0.622 0.378
G35 Multiple sclerosis
0.000 0.628 0.372
K70.0 Alcoholic fatty liver
0.000 0.630 0.370
E04.8 Other specified non-toxic goitre
0.000 0.632 0.368
D82.1 Di George's syndrome
0.001 0.636 0.363
E04.2 Non-toxic multinodular goitre
0.000 0.641 0.359
E05.8 Other thyrotoxicosis
0.001 0.642 0.357
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.647 0.353
K72 Hepatic failure, not elsewhere classified
0.000 0.648 0.352
K75.0 Abscess of liver
0.000 0.649 0.351
D56.9 Thalassaemia, unspecified
0.000 0.662 0.337
D56.8 Other thalassaemias
0.000 0.662 0.337
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.662 0.337
D56.2 Delta-beta thalassaemia
0.000 0.662 0.337
D56.0 Alpha thalassaemia
0.000 0.662 0.337
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.665 0.335
E07.1 Dyshormogenetic goitre
0.000 0.666 0.333
E07.0 Hypersecretion of calcitonin
0.000 0.666 0.333
D53.9 Nutritional anaemia, unspecified
0.000 0.682 0.317
K74 Fibrosis and cirrhosis of liver
0.000 0.683 0.317
E06.4 Drug-induced thyroiditis
0.000 0.684 0.315
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.684 0.315
E06.0 Acute thyroiditis
0.000 0.684 0.315
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.686 0.314
K75.2 Nonspecific reactive hepatitis
0.000 0.686 0.314
K75.1 Phlebitis of portal vein
0.000 0.686 0.314
K74.0 Hepatic fibrosis
0.000 0.688 0.312
K77 Liver disorders in diseases classified elsewhere
0.000 0.691 0.309
E06.5 Other chronic thyroiditis
0.000 0.693 0.307
K90.8 Other intestinal malabsorption
0.000 0.694 0.306
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.696 0.304
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.696 0.304
K72.0 Acute and subacute hepatic failure
0.000 0.703 0.297
D56.1 Beta thalassaemia
0.001 0.704 0.296
D75 Other diseases of blood and blood-forming organs
0.000 0.726 0.274
E04.1 Non-toxic single thyroid nodule
0.000 0.731 0.269
K72.9 Hepatic failure, unspecified
0.000 0.735 0.265
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.735 0.264
D56.3 Thalassaemia trait
0.001 0.737 0.262
K70.4 Alcoholic hepatic failure
0.000 0.738 0.262
K71 Toxic liver disease
0.000 0.743 0.257
D73 Diseases of spleen
0.000 0.743 0.256
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.761 0.239
K72.1 Chronic hepatic failure
0.000 0.766 0.234
E06.9 Thyroiditis, unspecified
0.000 0.770 0.229
K74.4 Secondary biliary cirrhosis
0.000 0.772 0.227
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.772 0.227
D75.0 Familial erythrocytosis
0.000 0.776 0.224
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.777 0.223
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.778 0.221
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.778 0.221
L40-L45 Papulosquamous disorders
0.001 0.788 0.212
E04.9 Non-toxic goitre, unspecified
0.000 0.795 0.205
K74.1 Hepatic sclerosis
0.000 0.797 0.203
D73.1 Hypersplenism
0.000 0.804 0.195
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.810 0.190
D73.5 Infarction of spleen
0.000 0.812 0.187
K70.3 Alcoholic cirrhosis of liver
0.000 0.813 0.187
E06.1 Subacute thyroiditis
0.001 0.814 0.185
K71.9 Toxic liver disease, unspecified
0.000 0.815 0.184
K71.8 Toxic liver disease with other disorders of liver
0.000 0.815 0.184
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.815 0.184
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.815 0.184
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.815 0.184
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.815 0.184
K71.2 Toxic liver disease with acute hepatitis
0.000 0.815 0.184
K71.0 Toxic liver disease with cholestasis
0.000 0.815 0.184
D73.2 Chronic congestive splenomegaly
0.000 0.816 0.184
D73.3 Abscess of spleen
0.000 0.817 0.182
D73.9 Disease of spleen, unspecified
0.000 0.824 0.176
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.836 0.163
D73.4 Cyst of spleen
0.001 0.838 0.161
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.840 0.160
K74.5 Biliary cirrhosis, unspecified
0.000 0.846 0.154
L44 Other papulosquamous disorders
0.001 0.848 0.152
L41 Parapsoriasis
0.001 0.848 0.152
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.848 0.152
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.850 0.150
K74.6 Other and unspecified cirrhosis of liver
0.000 0.857 0.143
D73.8 Other diseases of spleen
0.001 0.872 0.127
M06.9 Rheumatoid arthritis, unspecified
0.127 0.873 0.000
M06 Other rheumatoid arthritis
0.122 0.878 0.000
D75.2 Essential thrombocytosis
0.000 0.881 0.119
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.118 0.882 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.882 0.118
L42 Pityriasis rosea
0.001 0.884 0.115
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.115 0.885 0.000
M06.3 Rheumatoid nodule
0.112 0.888 0.000
K90-K93 Other diseases of the digestive system
0.000 0.889 0.111
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.111 0.889 0.000
K75.9 Inflammatory liver disease, unspecified
0.001 0.890 0.109
L41.9 Parapsoriasis, unspecified
0.001 0.890 0.109
L41.8 Other parapsoriasis
0.001 0.890 0.109
L41.5 Retiform parapsoriasis
0.001 0.890 0.109
L41.4 Large plaque parapsoriasis
0.001 0.890 0.109
L41.3 Small plaque parapsoriasis
0.001 0.890 0.109
L41.2 Lymphomatoid papulosis
0.001 0.890 0.109
L41.1 Pityriasis lichenoides chronica
0.001 0.890 0.109
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.890 0.109
L44.9 Papulosquamous disorder, unspecified
0.001 0.890 0.109
L44.8 Other specified papulosquamous disorders
0.001 0.890 0.109
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.890 0.109
L44.3 Lichen ruber moniliformis
0.001 0.890 0.109
L44.2 Lichen striatus
0.001 0.890 0.109
L44.1 Lichen nitidus
0.001 0.890 0.109
L44.0 Pityriasis rubra pilaris
0.001 0.890 0.109
M06.0 Seronegative rheumatoid arthritis
0.109 0.891 0.000
M06.34 Rheumatoid nodule (Hand)
0.108 0.892 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.107 0.893 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.104 0.896 0.000
G36 Other acute disseminated demyelination
0.000 0.897 0.102
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.101 0.899 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.101 0.899 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.094 0.906 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.094 0.906 0.000
E27 Other disorders of adrenal gland
0.000 0.908 0.092
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.091 0.909 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.909 0.091
M06.8 Other specified rheumatoid arthritis
0.091 0.909 0.000
M06.4 Inflammatory polyarthropathy
0.090 0.910 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.910 0.090
M06.2 Rheumatoid bursitis
0.088 0.912 0.000
M06.1 Adult-onset Still's disease
0.088 0.912 0.000
Chapter VI Diseases of the nervous system
0.000 0.915 0.085
E20-E35 Disorders of other endocrine glands
0.000 0.916 0.084
M06.04 Seronegative rheumatoid arthritis (Hand)
0.084 0.916 0.000
Chapter XI Diseases of the digestive system
0.000 0.917 0.083
E07.9 Disorder of thyroid, unspecified
0.000 0.917 0.083
G62.9 Polyneuropathy, unspecified
0.000 0.917 0.083
M06.33 Rheumatoid nodule (Forearm)
0.082 0.918 0.000
K74.3 Primary biliary cirrhosis
0.000 0.918 0.082
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.081 0.919 0.000
G62 Other polyneuropathies
0.000 0.919 0.081
M06.39 Rheumatoid nodule (Site unspecified)
0.080 0.919 0.000
M06.38 Rheumatoid nodule (Other)
0.080 0.919 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.080 0.919 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.080 0.919 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.080 0.919 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.920 0.080
M05.9 Seropositive rheumatoid arthritis, unspecified
0.080 0.920 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.080 0.920 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.080 0.920 0.000
E27.2 Addisonian crisis
0.000 0.921 0.079
M05-M14 Inflammatory polyarthropathies
0.079 0.921 0.000
M05 Seropositive rheumatoid arthritis
0.079 0.921 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.921 0.079
M06.08 Seronegative rheumatoid arthritis (Other)
0.079 0.921 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.079 0.921 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.079 0.921 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.078 0.922 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.922 0.078
G30-G32 Other degenerative diseases of the nervous system
0.000 0.924 0.076
G70-G73 Diseases of myoneural junction and muscle
0.000 0.924 0.076
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.075 0.925 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.075 0.925 0.000
# Top node
0.000 0.925 0.075
G36.9 Acute disseminated demyelination, unspecified
0.000 0.926 0.074
G36.8 Other specified acute disseminated demyelination
0.000 0.926 0.074
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.926 0.074
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.926 0.074
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.074 0.926 0.000
D68 Other coagulation defects
0.000 0.927 0.073
D75.8 Other specified diseases of blood and blood-forming organs
0.001 0.927 0.072
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.927 0.072
D75.1 Secondary polycythaemia
0.000 0.929 0.071
G62.1 Alcoholic polyneuropathy
0.000 0.929 0.071
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.070 0.930 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.931 0.069
E24 Cushing's syndrome
0.000 0.931 0.069
M06.37 Rheumatoid nodule (Ankle and foot)
0.069 0.931 0.000
E20 Hypoparathyroidism
0.000 0.931 0.069
G36.0 Neuromyelitis optica [Devic]
0.000 0.931 0.068
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.068 0.932 0.000
L50-L54 Urticaria and erythema
0.000 0.932 0.068
G31.2 Degeneration of nervous system due to alcohol
0.000 0.933 0.067
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.067 0.933 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.934 0.066
E27.0 Other adrenocortical overactivity
0.000 0.934 0.066
L10-L14 Bullous disorders
0.000 0.934 0.066
G70 Myasthenia gravis and other myoneural disorders
0.000 0.934 0.066
M14 Arthropathies in other diseases classified elsewhere
0.066 0.934 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.065 0.935 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.065 0.935 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.065 0.935 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.065 0.935 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.065 0.935 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.065 0.935 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.065 0.935 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.065 0.935 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.065 0.935 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.065 0.935 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.065 0.935 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.065 0.935 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.065 0.935 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.065 0.935 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.065 0.935 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.065 0.935 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.065 0.935 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.065 0.935 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.064 0.936 0.000
G62.0 Drug-induced polyneuropathy
0.000 0.936 0.064
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.064 0.936 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.936 0.064
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.064 0.936 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.063 0.937 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.063 0.937 0.000
M06.18 Adult-onset Still's disease (Other)
0.063 0.937 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.063 0.937 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.063 0.937 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.063 0.937 0.000
M06.14 Adult-onset Still's disease (Hand)
0.063 0.937 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.063 0.937 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.063 0.937 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.063 0.937 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.063 0.937 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.063 0.937 0.000
M06.28 Rheumatoid bursitis (Other)
0.063 0.937 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.063 0.937 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.063 0.937 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.063 0.937 0.000
M06.24 Rheumatoid bursitis (Hand)
0.063 0.937 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.063 0.937 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.063 0.937 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.063 0.937 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.063 0.937 0.000
E34 Other endocrine disorders
0.000 0.937 0.063
E25 Adrenogenital disorders
0.000 0.937 0.062
G71 Primary disorders of muscles
0.000 0.937 0.062
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.062 0.938 0.000
L50 Urticaria
0.000 0.939 0.061
M05.1 Rheumatoid lung disease
0.061 0.939 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.939 0.061
G31.0 Circumscribed brain atrophy
0.000 0.939 0.061
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.939 0.061
E32 Diseases of thymus
0.000 0.939 0.061
E31 Polyglandular dysfunction
0.000 0.939 0.061
E30 Disorders of puberty, not elsewhere classified
0.000 0.939 0.061
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.061 0.939 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.061 0.939 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.939 0.061
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.939 0.060
G00 Bacterial meningitis, not elsewhere classified
0.000 0.940 0.060
D68.6 Other Thrombophilia
0.000 0.941 0.059
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.059 0.941 0.000
G70.0 Myasthenia gravis
0.000 0.941 0.058
G62.2 Polyneuropathy due to other toxic agents
0.000 0.942 0.058
E20.9 Hypoparathyroidism, unspecified
0.000 0.942 0.058
L43 Lichen planus
0.002 0.942 0.056
M08 Juvenile arthritis
0.058 0.942 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.942 0.058
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.942 0.058
K93.1 Megacolon in Chagas' disease
0.000 0.942 0.058
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.942 0.058
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.057 0.942 0.000
G60 Hereditary and idiopathic neuropathy
0.000 0.943 0.057
M14.6 Neuropathic arthropathy
0.057 0.943 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.057 0.943 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.057 0.943 0.000
M05.0 Felty's syndrome
0.057 0.943 0.000
G64 Other disorders of peripheral nervous system
0.000 0.943 0.057
M05.2 Rheumatoid vasculitis
0.056 0.944 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.056 0.944 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.944 0.056
G83 Other paralytic syndromes
0.000 0.944 0.056
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.945 0.055
L13 Other bullous disorders
0.000 0.945 0.055
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.945 0.055
M07 Psoriatic and enteropathic arthropathies
0.036 0.945 0.019
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.945 0.055
L52 Erythema nodosum
0.000 0.945 0.055
M11 Other crystal arthropathies
0.054 0.945 0.000
G81 Hemiplegia
0.000 0.945 0.055
L11 Other acantholytic disorders
0.000 0.945 0.054
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.945 0.054
E40-E46 Malnutrition
0.000 0.946 0.054
E24.9 Cushing's syndrome, unspecified
0.000 0.946 0.053

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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