TreeWAS – Variant ID: rs9263875

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E03 Other hypothyroidism	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.995	0.005	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.006	0.994
M06.3 Rheumatoid nodule	0.992	0.008	0.000
M05 Seropositive rheumatoid arthritis	0.991	0.009	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.990	0.010	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.990	0.010	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.010	0.990
M05-M14 Inflammatory polyarthropathies	0.989	0.011	0.000
M06.34 Rheumatoid nodule (Hand)	0.980	0.020	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.965	0.035	0.000
L40.0 Psoriasis vulgaris	0.000	0.040	0.960
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.950	0.050	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.949	0.051	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.938	0.062	0.000
J45.9 Asthma, unspecified	0.935	0.065	0.000
E06 Thyroiditis	0.000	0.070	0.930
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.916	0.084	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.089	0.911
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.897	0.103	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.893	0.107	0.000
E06.3 Autoimmune thyroiditis	0.000	0.113	0.887
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.827	0.173	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.189	0.811
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.192	0.808
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.195	0.805
L40.1 Generalised pustular psoriasis	0.000	0.199	0.801
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.793	0.207	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.207	0.793
D72 Other disorders of white blood cells	0.000	0.212	0.788
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.212	0.788
D69.6 Thrombocytopenia, unspecified	0.000	0.213	0.787
D70 Agranulocytosis	0.000	0.217	0.783
D80-D89 Certain disorders involving the immune mechanism	0.000	0.224	0.776
M06.0 Seronegative rheumatoid arthritis	0.774	0.226	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.229	0.771
M06.36 Rheumatoid nodule (Lower leg)	0.769	0.231	0.000
L40.4 Guttate psoriasis	0.000	0.235	0.765
M12 Other specific arthropathies	0.765	0.235	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.761	0.239	0.000
D60-D64 Aplastic and other anaemias	0.000	0.242	0.758
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.757	0.243	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.756	0.244	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.245	0.755
E06.9 Thyroiditis, unspecified	0.000	0.247	0.753
M06.30 Rheumatoid nodule (Multiple sites)	0.752	0.248	0.000
E03.8 Other specified hypothyroidism	0.000	0.248	0.752
M06.33 Rheumatoid nodule (Forearm)	0.748	0.252	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.253	0.747
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.745	0.255	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.743	0.257	0.000
D61 Other aplastic anaemias	0.000	0.258	0.742
M14 Arthropathies in other diseases classified elsewhere	0.739	0.261	0.000
M08 Juvenile arthritis	0.735	0.265	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.274	0.726
D66 Hereditary factor VIII deficiency	0.000	0.276	0.724
M05.1 Rheumatoid lung disease	0.723	0.277	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.713	0.287	0.000
M06.8 Other specified rheumatoid arthritis	0.712	0.288	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.711	0.289	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.711	0.289	0.000
M06.38 Rheumatoid nodule (Other)	0.711	0.289	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.711	0.289	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.711	0.289	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.710	0.289	0.000
M05.2 Rheumatoid vasculitis	0.710	0.289	0.000
M05.0 Felty's syndrome	0.710	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.709	0.291	0.000
D86 Sarcoidosis	0.000	0.292	0.708
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.702	0.298	0.000
D69.2 Other nonthrombocytopenic purpura	0.000	0.302	0.698
M05.8 Other seropositive rheumatoid arthritis	0.698	0.302	0.000
M06.4 Inflammatory polyarthropathy	0.698	0.302	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.312	0.688
L40.8 Other psoriasis	0.000	0.314	0.686
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.316	0.684
E03.1 Congenital hypothyroidism without goitre	0.000	0.320	0.680
D69.4 Other primary thrombocytopenia	0.000	0.324	0.676
E06.4 Drug-induced thyroiditis	0.000	0.333	0.666
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.333	0.666
E06.0 Acute thyroiditis	0.000	0.333	0.666
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.342	0.658
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.655	0.345	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.359	0.641
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.359	0.641
D86.3 Sarcoidosis of skin	0.000	0.366	0.634
D84 Other immunodeficiencies	0.000	0.368	0.632
D55-D59 Haemolytic anaemias	0.000	0.371	0.629
E06.5 Other chronic thyroiditis	0.000	0.371	0.629
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.626	0.374	0.000
D72.1 Eosinophilia	0.000	0.403	0.597
D69.1 Qualitative platelet defects	0.000	0.403	0.597
D61.0 Constitutional aplastic anaemia	0.000	0.403	0.597
E05.8 Other thyrotoxicosis	0.000	0.409	0.591
D83 Common variable immunodeficiency	0.000	0.409	0.591
M06.04 Seronegative rheumatoid arthritis (Hand)	0.590	0.410	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.588	0.412	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.582	0.418	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.419	0.580
D74 Methaemoglobinaemia	0.000	0.420	0.580
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.420	0.580
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.420	0.580
M12.5 Traumatic arthropathy	0.577	0.423	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.429	0.571
D69.8 Other specified haemorrhagic conditions	0.000	0.431	0.568
M12.2 Villonodular synovitis (pigmented)	0.568	0.432	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.435	0.565
D72.0 Genetic anomalies of leukocytes	0.000	0.435	0.565
D67 Hereditary factor IX deficiency	0.000	0.438	0.562
M12.3 Palindromic rheumatism	0.562	0.438	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.442	0.558
D81 Combined immunodeficiencies	0.000	0.444	0.556
M06.08 Seronegative rheumatoid arthritis (Other)	0.555	0.445	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.555	0.445	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.555	0.445	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.555	0.445	0.000
D68 Other coagulation defects	0.000	0.447	0.553
D69.5 Secondary thrombocytopenia	0.000	0.447	0.553
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.449	0.551
M12.8 Other specific arthropathies, not elsewhere classified	0.548	0.452	0.000
M12.4 Intermittent hydrarthrosis	0.548	0.452	0.000
M12.1 Kaschin-Beck disease	0.548	0.452	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.548	0.452	0.000
M08.2 Juvenile arthritis with systemic onset	0.543	0.457	0.000
M08.0 Juvenile rheumatoid arthritis	0.538	0.461	0.000
E06.1 Subacute thyroiditis	0.000	0.465	0.535
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.534	0.466	0.000
D61.8 Other specified aplastic anaemias	0.000	0.468	0.532
D61.3 Idiopathic aplastic anaemia	0.000	0.468	0.532
D61.2 Aplastic anaemia due to other external agents	0.000	0.468	0.532
M05.19 Rheumatoid lung disease (Site unspecified)	0.530	0.470	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.530	0.470	0.000
M14.4 Arthropathy in amyloidosis	0.530	0.470	0.000
M14.3 Lipoid dermatoarthritis	0.530	0.470	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.530	0.470	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.530	0.470	0.000
M14.6 Neuropathic arthropathy	0.529	0.471	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.473	0.527
M08.9 Juvenile arthritis, unspecified	0.527	0.473	0.000
M08.8 Other juvenile arthritis	0.527	0.473	0.000
M08.4 Pauciarticular juvenile arthritis	0.527	0.473	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.527	0.473	0.000
M08.1 Juvenile ankylosing spondylitis	0.527	0.473	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.473	0.527
D84.9 Immunodeficiency, unspecified	0.000	0.476	0.524
D59 Acquired haemolytic anaemia	0.000	0.478	0.522
D76.3 Other histiocytosis syndromes	0.000	0.479	0.521
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.480	0.520
D61.1 Drug-induced aplastic anaemia	0.000	0.481	0.519
M05.18 Rheumatoid lung disease (Other)	0.518	0.482	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.518	0.482	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.518	0.482	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.518	0.482	0.000
M05.14 Rheumatoid lung disease (Hand)	0.518	0.482	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.518	0.482	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.518	0.482	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.518	0.482	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.518	0.482	0.000
D64 Other anaemias	0.000	0.485	0.515
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.513
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.510	0.489	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.510	0.489	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.510	0.489	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.510	0.489	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.510	0.489	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.510	0.489	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.510	0.489	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.510	0.489	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.510	0.489	0.000
M05.09 Felty's syndrome (Site unspecified)	0.509	0.490	0.000
M05.08 Felty's syndrome (Other)	0.509	0.490	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.509	0.490	0.000
M05.06 Felty's syndrome (Lower leg)	0.509	0.490	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.509	0.490	0.000
M05.04 Felty's syndrome (Hand)	0.509	0.490	0.000
M05.03 Felty's syndrome (Forearm)	0.509	0.490	0.000
M05.02 Felty's syndrome (Upper arm)	0.509	0.490	0.000
M05.01 Felty's syndrome (Shoulder region)	0.509	0.490	0.000
M05.00 Felty's syndrome (Multiple sites)	0.509	0.490	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.509	0.490	0.000
M05.28 Rheumatoid vasculitis (Other)	0.509	0.490	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.509	0.490	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.509	0.490	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.509	0.490	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.509	0.490	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.509	0.490	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.509	0.490	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.509	0.490	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.509	0.490	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.509	0.490	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.509	0.490	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.509	0.490	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.509	0.490	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.509	0.490	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.509	0.490	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.509	0.490	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.509	0.490	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.509	0.490	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.509	0.490	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.491	0.509
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.508	0.492	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.508	0.492	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.508	0.492	0.000
M09.0 Juvenile arthritis in psoriasis	0.508	0.492	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.506	0.494	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.500	0.499	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.500	0.499	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.500	0.499	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.500	0.499	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.500	0.499	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.500	0.499	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.500	0.499	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.500	0.499	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.500	0.499	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.500	0.499	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.500	0.499	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.500	0.499	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.500	0.499	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.500	0.499	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.500	0.499	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.500	0.499	0.000
E07 Other disorders of thyroid	0.000	0.500	0.500
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.500	0.499
D86.0 Sarcoidosis of lung	0.000	0.501	0.498
D89.1 Cryoglobulinaemia	0.000	0.503	0.497
D68.8 Other specified coagulation defects	0.000	0.504	0.496
D84.1 Defects in the complement system	0.000	0.507	0.493
M14.2 Diabetic arthropathy	0.492	0.508	0.000
D68.6 Other Thrombophilia	0.000	0.509	0.491
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.510	0.490
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.488	0.512	0.000
M07 Psoriatic and enteropathic arthropathies	0.424	0.515	0.061
D75.0 Familial erythrocytosis	0.000	0.516	0.484
D82 Immunodeficiency associated with other major defects	0.000	0.522	0.478
D63.0 Anaemia in neoplastic disease	0.000	0.523	0.477
D58 Other hereditary haemolytic anaemias	0.000	0.523	0.477
M11 Other crystal arthropathies	0.477	0.523	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.524	0.475
M06.46 Inflammatory polyarthropathy (Lower leg)	0.473	0.526	0.000
D89.3 Immune reconstitution syndrome	0.000	0.528	0.472
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.469	0.531	0.000
D57 Sickle-cell disorders	0.000	0.536	0.464
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.540	0.459
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.540	0.459
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.540	0.459
D86.1 Sarcoidosis of lymph nodes	0.000	0.542	0.458
D83.9 Common variable immunodeficiency, unspecified	0.000	0.542	0.458
D69.0 Allergic purpura	0.000	0.546	0.453
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.546	0.453
D55 Anaemia due to enzyme disorders	0.000	0.549	0.451
M10 Gout	0.449	0.551	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.448	0.552	0.000
D68.0 Von Willebrand's disease	0.000	0.556	0.444
M12.57 Traumatic arthropathy (Ankle and foot)	0.442	0.558	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.562	0.437
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.563	0.437
M12.30 Palindromic rheumatism (Multiple sites)	0.424	0.576	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.576	0.423
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.576	0.423
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.576	0.423
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.576	0.423
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.580	0.420
D73 Diseases of spleen	0.000	0.581	0.419
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.417	0.582	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.583	0.417
D74.9 Methaemoglobinaemia, unspecified	0.000	0.584	0.416
D74.8 Other methaemoglobinaemias	0.000	0.584	0.416
D74.0 Congenital methaemoglobinaemia	0.000	0.584	0.416
D84.8 Other specified immunodeficiencies	0.000	0.585	0.415
M12.59 Traumatic arthropathy (Site unspecified)	0.414	0.586	0.000
M12.58 Traumatic arthropathy (Other)	0.414	0.586	0.000
M12.56 Traumatic arthropathy (Lower leg)	0.414	0.586	0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.414	0.586	0.000
M12.54 Traumatic arthropathy (Hand)	0.414	0.586	0.000
M12.53 Traumatic arthropathy (Forearm)	0.414	0.586	0.000
M12.52 Traumatic arthropathy (Upper arm)	0.414	0.586	0.000
M12.51 Traumatic arthropathy (Shoulder region)	0.414	0.586	0.000
M12.50 Traumatic arthropathy (Multiple sites)	0.414	0.586	0.000
K90 Intestinal malabsorption	0.000	0.587	0.413
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.588	0.412
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.588	0.412
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.591	0.409
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.591	0.409
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.591	0.409
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.591	0.409
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.407	0.592	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.407	0.593	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.407	0.593	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.407	0.593	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.407	0.593	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.407	0.593	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.407	0.593	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.407	0.593	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.407	0.593	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.593	0.407
M08.29 Juvenile arthritis with systemic onset (Site unspecified)	0.405	0.595	0.000
M12.38 Palindromic rheumatism (Other)	0.403	0.597	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.403	0.597	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.403	0.597	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.403	0.597	0.000
M12.34 Palindromic rheumatism (Hand)	0.403	0.597	0.000
M12.33 Palindromic rheumatism (Forearm)	0.403	0.597	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.403	0.597	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.403	0.597	0.000
D64.8 Other specified anaemias	0.000	0.599	0.401
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.600	0.400
D81.9 Combined immunodeficiency, unspecified	0.000	0.601	0.399
D81.8 Other combined immunodeficiencies	0.000	0.601	0.399
D81.7 Major histocompatibility complex class II deficiency	0.000	0.601	0.399
D81.6 Major histocompatibility complex class I deficiency	0.000	0.601	0.399
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.601	0.399
D81.4 Nezelof's syndrome	0.000	0.601	0.399
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.601	0.399
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.601	0.399
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.601	0.399
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.601	0.399
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.397	0.602	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.395	0.605	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.605	0.395
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.393	0.607	0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.393	0.607	0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.393	0.607	0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.393	0.607	0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.393	0.607	0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.393	0.607	0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.393	0.607	0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.393	0.607	0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.393	0.607	0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.393	0.607	0.000
M12.19 Kaschin-Beck disease (Site unspecified)	0.393	0.607	0.000
M12.18 Kaschin-Beck disease (Other)	0.393	0.607	0.000
M12.17 Kaschin-Beck disease (Ankle and foot)	0.393	0.607	0.000
M12.16 Kaschin-Beck disease (Lower leg)	0.393	0.607	0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.393	0.607	0.000
M12.14 Kaschin-Beck disease (Hand)	0.393	0.607	0.000
M12.13 Kaschin-Beck disease (Forearm)	0.393	0.607	0.000
M12.12 Kaschin-Beck disease (Upper arm)	0.393	0.607	0.000
M12.11 Kaschin-Beck disease (Shoulder region)	0.393	0.607	0.000
M12.10 Kaschin-Beck disease (Multiple sites)	0.393	0.607	0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.393	0.607	0.000
M12.48 Intermittent hydrarthrosis (Other)	0.393	0.607	0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.393	0.607	0.000
M12.46 Intermittent hydrarthrosis (Lower leg)	0.393	0.607	0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.393	0.607	0.000
M12.44 Intermittent hydrarthrosis (Hand)	0.393	0.607	0.000
M12.43 Intermittent hydrarthrosis (Forearm)	0.393	0.607	0.000
M12.42 Intermittent hydrarthrosis (Upper arm)	0.393	0.607	0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.393	0.607	0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.393	0.607	0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.393	0.607	0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.393	0.607	0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.393	0.607	0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.393	0.607	0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.393	0.607	0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.393	0.607	0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.393	0.607	0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.393	0.607	0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.393	0.607	0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.393	0.607	0.000
M08.28 Juvenile arthritis with systemic onset (Other)	0.389	0.611	0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)	0.389	0.611	0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)	0.389	0.611	0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)	0.389	0.611	0.000
M08.24 Juvenile arthritis with systemic onset (Hand)	0.389	0.611	0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)	0.389	0.611	0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)	0.389	0.611	0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)	0.389	0.611	0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)	0.389	0.611	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.611	0.389
D50-D53 Nutritional anaemias	0.000	0.613	0.387
D68.9 Coagulation defect, unspecified	0.000	0.614	0.386
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.386	0.614	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.386	0.614	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.386	0.614	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.386	0.614	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.386	0.614	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.386	0.614	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.386	0.614	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.386	0.614	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.386	0.614	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.615	0.385
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.378	0.622	0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.378	0.622	0.000
M08.18 Juvenile ankylosing spondylitis (Other)	0.378	0.622	0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.378	0.622	0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.378	0.622	0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.378	0.622	0.000
M08.14 Juvenile ankylosing spondylitis (Hand)	0.378	0.622	0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.378	0.622	0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.378	0.622	0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)	0.378	0.622	0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)	0.378	0.622	0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)	0.378	0.622	0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)	0.378	0.622	0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)	0.378	0.622	0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)	0.378	0.622	0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)	0.378	0.622	0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)	0.378	0.622	0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)	0.378	0.622	0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)	0.378	0.622	0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)	0.378	0.622	0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)	0.378	0.622	0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)	0.378	0.622	0.000
M08.48 Pauciarticular juvenile arthritis (Other)	0.378	0.622	0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)	0.378	0.622	0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)	0.378	0.622	0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)	0.378	0.622	0.000
M08.44 Pauciarticular juvenile arthritis (Hand)	0.378	0.622	0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)	0.378	0.622	0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)	0.378	0.622	0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)	0.378	0.622	0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)	0.378	0.622	0.000
M08.89 Other juvenile arthritis (Site unspecified)	0.378	0.622	0.000
M08.88 Other juvenile arthritis (Other)	0.378	0.622	0.000
M08.87 Other juvenile arthritis (Ankle and foot)	0.378	0.622	0.000
M08.86 Other juvenile arthritis (Lower leg)	0.378	0.622	0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)	0.378	0.622	0.000
M08.84 Other juvenile arthritis (Hand)	0.378	0.622	0.000
M08.83 Other juvenile arthritis (Forearm)	0.378	0.622	0.000
M08.82 Other juvenile arthritis (Upper arm)	0.378	0.622	0.000
M08.81 Other juvenile arthritis (Shoulder region)	0.378	0.622	0.000
M08.80 Other juvenile arthritis (Multiple sites)	0.378	0.622	0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.378	0.622	0.000
M08.98 Juvenile arthritis, unspecified (Other)	0.378	0.622	0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)	0.378	0.622	0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)	0.378	0.622	0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)	0.378	0.622	0.000
M08.94 Juvenile arthritis, unspecified (Hand)	0.378	0.622	0.000
M08.93 Juvenile arthritis, unspecified (Forearm)	0.378	0.622	0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)	0.378	0.622	0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)	0.378	0.622	0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)	0.378	0.622	0.000
E04 Other non-toxic goitre	0.000	0.623	0.377
D86.8 Sarcoidosis of other and combined sites	0.000	0.624	0.376
D59.8 Other acquired haemolytic anaemias	0.000	0.625	0.374
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.625	0.374
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.625	0.374
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.625	0.374
D59.3 Haemolytic-uraemic syndrome	0.000	0.625	0.374
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.625	0.374
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.625	0.374
E07.8 Other specified disorders of thyroid	0.000	0.627	0.373
D64.4 Congenital dyserythropoietic anaemia	0.000	0.631	0.369
D64.3 Other sideroblastic anaemias	0.000	0.631	0.369
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.631	0.369
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.631	0.369
D64.0 Hereditary sideroblastic anaemia	0.000	0.631	0.369
M09.09 Juvenile arthritis in psoriasis (Site unspecified)	0.364	0.635	0.000
M09.08 Juvenile arthritis in psoriasis (Other)	0.364	0.635	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations