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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9264532
log Bayes Factor = 72.8338
Chromosome 6   position 31,234,381  (GRCh37) Explore rs9264532 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M45 Ankylosing spondylitis
0.996 0.004 0.000
E11.9 Without complications
0.000 0.004 0.996
E11 Non-insulin-dependent diabetes mellitus
0.000 0.005 0.995
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.993 0.007 0.000
E83.1 Disorders of iron metabolism
0.983 0.017 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.052 0.948
E14 Unspecified diabetes mellitus
0.000 0.054 0.946
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.058 0.942
E70-E90 Metabolic disorders
0.000 0.059 0.941
E11.0 With coma
0.000 0.059 0.941
E78.0 Pure hypercholesterolaemia
0.000 0.061 0.939
E16 Other disorders of pancreatic internal secretion
0.000 0.089 0.911
E78.2 Mixed hyperlipidaemia
0.000 0.094 0.906
E11.1 With ketoacidosis
0.000 0.111 0.889
E10.5 With peripheral circulatory complications
0.000 0.119 0.881
E16.2 Hypoglycaemia, unspecified
0.000 0.129 0.871
M45.X2 Ankylosing spondylitis (Cervical region)
0.869 0.131 0.000
E10.0 With coma
0.000 0.131 0.869
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.162 0.838
E78.4 Other hyperlipidaemia
0.000 0.165 0.835
E10.4 With neurological complications
0.000 0.178 0.822
M45.X6 Ankylosing spondylitis (Lumbar region)
0.816 0.184 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.187 0.813
E20-E35 Disorders of other endocrine glands
0.000 0.191 0.809
E40-E46 Malnutrition
0.000 0.205 0.795
E74 Other disorders of carbohydrate metabolism
0.000 0.208 0.791
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.212 0.788
E13 Other specified diabetes mellitus
0.000 0.217 0.783
E14.1 With ketoacidosis
0.000 0.220 0.780
E16.1 Other hypoglycaemia
0.000 0.220 0.780
K90 Intestinal malabsorption
0.000 0.223 0.777
E10.8 With unspecified complications
0.000 0.226 0.774
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.772 0.228 0.000
L40 Psoriasis
0.000 0.228 0.772
E14.9 Without complications
0.000 0.228 0.772
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.230 0.770
E14.3 With ophthalmic complications
0.000 0.241 0.759
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.250 0.750
E14.8 With unspecified complications
0.000 0.253 0.747
E14.2 Withrenal complications
0.000 0.263 0.737
E10.6 With other specified complications
0.000 0.264 0.736
E21.3 Hyperparathyroidism, unspecified
0.000 0.266 0.734
E78.6 Lipoprotein deficiency
0.000 0.266 0.734
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.267 0.733
E14.6 With other specified complications
0.000 0.270 0.730
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.278 0.722
E21.0 Primary hyperparathyroidism
0.000 0.281 0.719
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
E03.8 Other specified hypothyroidism
0.000 0.284 0.715
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.714 0.286 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.714 0.286 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.714 0.286 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.714 0.286 0.000
E11.7 With multiple complications
0.000 0.286 0.713
E79 Disorders of purine and pyrimidine metabolism
0.000 0.286 0.714
L40.0 Psoriasis vulgaris
0.000 0.296 0.704
E14.5 With peripheral circulatory complications
0.000 0.310 0.690
E89.3 Postprocedural hypopituitarism
0.000 0.311 0.689
E10.2 With renal complications
0.000 0.311 0.689
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.316 0.684
E15 Nondiabetic hypoglycaemic coma
0.000 0.320 0.680
E22 Hyperfunction of pituitary gland
0.000 0.320 0.680
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.679 0.321 0.000
E14.7 With multiple complications
0.000 0.322 0.678
E14.0 With coma
0.000 0.322 0.678
E78.3 Hyperchylomicronaemia
0.000 0.324 0.676
E28 Ovarian dysfunction
0.000 0.325 0.675
E77 Disorders of glycoprotein metabolism
0.000 0.325 0.675
E76 Disorders of glycosaminoglycan metabolism
0.000 0.325 0.675
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.325 0.675
E70 Disorders of aromatic amino-acid metabolism
0.000 0.325 0.675
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.325 0.675
E88 Other metabolic disorders
0.000 0.331 0.669
E13.9 Without complications
0.000 0.345 0.655
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.347 0.653
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.347 0.653
E16.4 Abnormal secretion of gastrin
0.000 0.347 0.653
E16.3 Increased secretion of glucagon
0.000 0.347 0.653
E05.8 Other thyrotoxicosis
0.000 0.349 0.651
E89.2 Postprocedural hypoparathyroidism
0.000 0.351 0.649
E46 Unspecified protein-energy malnutrition
0.000 0.351 0.649
E72 Other disorders of amino-acid metabolism
0.000 0.359 0.641
E14.4 With neurological complications
0.000 0.361 0.639
E10.7 With multiple complications
0.000 0.363 0.636
E06 Thyroiditis
0.000 0.364 0.636
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.368 0.632
E84 Cystic fibrosis
0.000 0.377 0.623
E28.2 Polycystic ovarian syndrome
0.000 0.384 0.616
K90.9 Intestinal malabsorption, unspecified
0.000 0.385 0.615
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.387 0.613
E24 Cushing's syndrome
0.000 0.405 0.595
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.409 0.591
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.420 0.580
E32 Diseases of thymus
0.000 0.420 0.580
E30 Disorders of puberty, not elsewhere classified
0.000 0.420 0.580
L40.5 Arthropathic psoriasis
0.000 0.420 0.580
E73 Lactose intolerance
0.000 0.421 0.579
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.422 0.578
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.430 0.570
E45 Retarded development following protein-energy malnutrition
0.000 0.430 0.570
E43 Unspecified severe protein-energy malnutrition
0.000 0.430 0.570
E42 Marasmic kwashiorkor
0.000 0.430 0.570
E41 Nutritional marasmus
0.000 0.430 0.570
E40 Kwashiorkor
0.000 0.430 0.570
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.432 0.568
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.432 0.567
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.432 0.567
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.432 0.567
E74.2 Disorders of galactose metabolism
0.000 0.432 0.567
E74.1 Disorders of fructose metabolism
0.000 0.432 0.567
E74.0 Glycogen storage disease
0.000 0.432 0.567
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.434 0.566
I83 Varicose veins of lower extremities
0.566 0.434 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.435 0.565
E89.4 Postprocedural ovarian failure
0.000 0.438 0.562
E13.8 With unspecified complications
0.000 0.439 0.561
E13.7 With multiple complications
0.000 0.439 0.561
E13.6 With other specified complications
0.000 0.439 0.561
E13.5 With peripheral circulatory complications
0.000 0.439 0.561
E13.4 With neurological complications
0.000 0.439 0.561
E13.2 With renal complications
0.000 0.439 0.561
E13.1 With ketoacidosis
0.000 0.439 0.561
E13.0 With coma
0.000 0.439 0.561
L40.8 Other psoriasis
0.000 0.439 0.561
E25 Adrenogenital disorders
0.000 0.442 0.558
K90.3 Pancreatic steatorrhoea
0.000 0.443 0.557
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.443 0.557
K90.1 Tropical sprue
0.000 0.443 0.557
I83.0 Varicose veins of lower extremities with ulcer
0.556 0.444 0.000
L40.4 Guttate psoriasis
0.000 0.447 0.553
L40.2 Acrodermatitis continua
0.000 0.447 0.553
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.448 0.552
E89.5 Postprocedural testicular hypofunction
0.000 0.448 0.552
E89.1 Postprocedural hypoinsulinaemia
0.000 0.448 0.552
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.449 0.550
E31 Polyglandular dysfunction
0.000 0.456 0.544
E21.2 Other hyperparathyroidism
0.000 0.459 0.540
L40.1 Generalised pustular psoriasis
0.000 0.460 0.540
E11.6 With other specified complications
0.000 0.471 0.529
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.471 0.529
K90.8 Other intestinal malabsorption
0.000 0.473 0.527
E88.8 Other specified metabolic disorders
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E13.3 With ophthalmic complications
0.000 0.487 0.513
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.488 0.512
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.488 0.512
E79.1 Lesch-Nyhan syndrome
0.000 0.488 0.512
E11.5 With peripheral circulatory complications
0.000 0.490 0.510
E88.2 Lipomatosis, not elsewhere classified
0.000 0.493 0.507
E26 Hyperaldosteronism
0.000 0.497 0.503
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.503 0.497
E23 Hypofunction and other disorders of pituitary gland
0.000 0.505 0.495
E11.8 With unspecified complications
0.000 0.509 0.491
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.512 0.487
E22.8 Other hyperfunction of pituitary gland
0.000 0.512 0.487
E22.1 Hyperprolactinaemia
0.000 0.513 0.487
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.514 0.486
E85 Amyloidosis
0.000 0.515 0.484
E28.9 Ovarian dysfunction, unspecified
0.000 0.516 0.484
E28.8 Other ovarian dysfunction
0.000 0.516 0.484
E28.1 Androgen excess
0.000 0.516 0.484
E28.0 Oestrogen excess
0.000 0.516 0.484
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.516 0.484
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.516 0.484
E70.3 Albinism
0.000 0.516 0.484
E70.2 Disorders of tyrosine metabolism
0.000 0.516 0.484
E70.1 Other hyperphenylalaninaemias
0.000 0.516 0.484
E70.0 Classical phenylketonuria
0.000 0.516 0.484
E71.3 Disorders of fatty-acid metabolism
0.000 0.516 0.484
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.516 0.484
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.516 0.484
E71.0 Maple-syrup-urine disease
0.000 0.516 0.484
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.516 0.484
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.516 0.484
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.516 0.484
E76.2 Other mucopolysaccharidoses
0.000 0.516 0.484
E76.1 Mucopolysaccharidosis, type II
0.000 0.516 0.484
E76.0 Mucopolysaccharidosis, type I
0.000 0.516 0.484
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.516 0.484
E77.8 Other disorders of glycoprotein metabolism
0.000 0.516 0.484
E77.1 Defects in glycoprotein degradation
0.000 0.516 0.484
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.516 0.484
E88.9 Metabolic disorder, unspecified
0.000 0.520 0.479
E22.0 Acromegaly and pituitary gigantism
0.000 0.521 0.479
E24.0 Pituitary-dependent Cushing's disease
0.000 0.523 0.477
E88.3 Tumour lysis syndrome
0.000 0.534 0.466
L40.3 Pustulosis palmaris et plantaris
0.000 0.538 0.462
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.540 0.459
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.540 0.459
E72.5 Disorders of glycine metabolism
0.000 0.540 0.459
E72.4 Disorders of ornithine metabolism
0.000 0.540 0.459
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.540 0.459
E72.2 Disorders of urea cycle metabolism
0.000 0.540 0.459
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.540 0.459
E80.2 Other porphyria
0.000 0.543 0.457
E06.5 Other chronic thyroiditis
0.000 0.544 0.456
E06.4 Drug-induced thyroiditis
0.000 0.544 0.456
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.544 0.456
E06.1 Subacute thyroiditis
0.000 0.544 0.456
E06.0 Acute thyroiditis
0.000 0.544 0.456
E07 Other disorders of thyroid
0.000 0.545 0.454
E24.2 Drug-induced Cushing's syndrome
0.000 0.551 0.449
E84.8 Cystic fibrosis with other manifestations
0.000 0.553 0.447
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.553 0.447
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.553 0.447
E20 Hypoparathyroidism
0.000 0.555 0.444
E34 Other endocrine disorders
0.000 0.556 0.444
E06.3 Autoimmune thyroiditis
0.000 0.557 0.443
E75.6 Lipid storage disorder, unspecified
0.000 0.560 0.440
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.560 0.440
E75.3 Sphingolipidosis, unspecified
0.000 0.560 0.440
E75.2 Other sphingolipidosis
0.000 0.560 0.440
E75.1 Other gangliosidosis
0.000 0.560 0.440
E75.0 GM2 gangliosidosis
0.000 0.560 0.440
E29 Testicular dysfunction
0.000 0.561 0.439
E50-E64 Other nutritional deficiencies
0.000 0.566 0.434
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.428 0.572 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.573 0.427
E24.3 Ectopic ACTH syndrome
0.000 0.573 0.427
E24.1 Nelson's syndrome
0.000 0.573 0.427
E72.0 Disorders of amino-acid transport
0.000 0.574 0.426
E80.1 Porphyria cutanea tarda
0.000 0.576 0.424
E80.6 Other disorders of bilirubin metabolism
0.000 0.583 0.417
E24.9 Cushing's syndrome, unspecified
0.000 0.583 0.417
E30.9 Disorder of puberty, unspecified
0.000 0.584 0.416
E30.8 Other disorders of puberty
0.000 0.584 0.416
E30.1 Precocious puberty
0.000 0.584 0.416
E30.0 Delayed puberty
0.000 0.584 0.416
E32.9 Disease of thymus, unspecified
0.000 0.584 0.416
E32.8 Other diseases of thymus
0.000 0.584 0.416
E32.1 Abscess of thymus
0.000 0.584 0.416
E32.0 Persistent hyperplasia of thymus
0.000 0.584 0.416
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.584 0.416
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.584 0.416
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.584 0.416
E73.8 Other lactose intolerance
0.000 0.585 0.415
E73.1 Secondary lactase deficiency
0.000 0.585 0.415
E73.0 Congenital lactase deficiency
0.000 0.585 0.415
E44.1 Mild protein-energy malnutrition
0.000 0.591 0.409
E44.0 Moderate protein-energy malnutrition
0.000 0.591 0.409
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.594 0.406
E80.5 Crigler-Najjar syndrome
0.000 0.594 0.406
E80.3 Defects of catalase and peroxydase
0.000 0.594 0.406
E80.0 Hereditary erythropoietic porphyria
0.000 0.594 0.406
E25.9 Adrenogenital disorder, unspecified
0.000 0.599 0.400
E25.8 Other adrenogenital disorders
0.000 0.599 0.400
E84.9 Cystic fibrosis, unspecified
0.000 0.604 0.395
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.605 0.395
E83 Disorders of mineral metabolism
0.183 0.607 0.211
E06.9 Thyroiditis, unspecified
0.000 0.608 0.392
E31.9 Polyglandular dysfunction, unspecified
0.000 0.610 0.390
E31.8 Other polyglandular dysfunction
0.000 0.610 0.390
E31.1 Polyglandular hyperfunction
0.000 0.610 0.390
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.621 0.379
E75.5 Other lipid storage disorders
0.000 0.622 0.378
E23.2 Diabetes insipidus
0.000 0.624 0.376
E78.1 Pure hyperglyceridaemia
0.001 0.624 0.375
E23.6 Other disorders of pituitary gland
0.000 0.630 0.370
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.633 0.367
E28.3 Primary ovarian failure
0.000 0.635 0.364
E26.8 Other hyperaldosteronism
0.000 0.639 0.361
E26.1 Secondary hyperaldosteronism
0.000 0.639 0.361
E24.8 Other Cushing's syndrome
0.000 0.641 0.359
L40-L45 Papulosquamous disorders
0.000 0.643 0.357
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.645 0.355
E23.1 Drug-induced hypopituitarism
0.000 0.645 0.355
E31.0 Autoimmune polyglandular failure
0.000 0.646 0.354
E78.5 Hyperlipidaemia, unspecified
0.000 0.648 0.352
E26.0 Primary hyperaldosteronism
0.000 0.650 0.350
E23.7 Disorder of pituitary gland, unspecified
0.000 0.652 0.348
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.652 0.347
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.652 0.347
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.652 0.347
E34.9 Endocrine disorder, unspecified
0.000 0.657 0.342
E85.9 Amyloidosis, unspecified
0.000 0.667 0.333
E85.8 Other amyloidosis
0.000 0.670 0.330
E07.1 Dyshormogenetic goitre
0.000 0.674 0.326
E07.0 Hypersecretion of calcitonin
0.000 0.674 0.326
E61 Deficiency of other nutrient elements
0.000 0.681 0.319
E73.9 Lactose intolerance, unspecified
0.000 0.681 0.319
E20.8 Other hypoparathyroidism
0.000 0.681 0.319
E20.1 Pseudohypoparathyroidism
0.000 0.681 0.319
E20.0 Idiopathic hypoparathyroidism
0.000 0.681 0.319
E34.5 Androgen resistance syndrome
0.000 0.681 0.318
E34.4 Constitutional tall stature
0.000 0.681 0.318
E34.3 Short stature, not elsewhere classified
0.000 0.681 0.318
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.681 0.318
E34.1 Other hypersecretion of intestinal hormones
0.000 0.681 0.318
E29.9 Testicular dysfunction, unspecified
0.000 0.685 0.315
E29.8 Other testicular dysfunction
0.000 0.685 0.315
E29.0 Testicular hyperfunction
0.000 0.685 0.315
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.689 0.311
E63 Other nutritional deficiencies
0.000 0.689 0.311
E50 Vitamin A deficiency
0.000 0.689 0.311
E60 Dietary zinc deficiency
0.000 0.689 0.311
E59 Dietary selenium deficiency
0.000 0.689 0.311
E52 Niacin deficiency [pellagra]
0.000 0.689 0.311
E55 Vitamin D deficiency
0.000 0.693 0.307
E27 Other disorders of adrenal gland
0.000 0.694 0.306
K51.9 Ulcerative colitis, unspecified
0.304 0.696 0.000
E51 Thiamine deficiency
0.000 0.696 0.304
E86 Volume depletion
0.000 0.696 0.304
E26.9 Hyperaldosteronism, unspecified
0.000 0.701 0.299
E56 Other vitamin deficiencies
0.000 0.702 0.298
E85.4 Organ-limited amyloidosis
0.000 0.703 0.297
E85.3 Secondary systemic amyloidosis
0.000 0.706 0.294
E58 Dietary calcium deficiency
0.000 0.706 0.294
E54 Ascorbic acid deficiency
0.000 0.712 0.288
E65-E68 Obesity and other hyperalimentation
0.001 0.714 0.285
E83.9 Disorder of mineral metabolism, unspecified
0.131 0.718 0.151
E83.8 Other disorders of mineral metabolism
0.131 0.718 0.151
E83.2 Disorders of zinc metabolism
0.131 0.718 0.151
E83.0 Disorders of copper metabolism
0.131 0.718 0.151
L43 Lichen planus
0.000 0.726 0.274
K51 Ulcerative colitis
0.266 0.734 0.000
E34.8 Other specified endocrine disorders
0.000 0.739 0.261
E27.9 Disorder of adrenal gland, unspecified
0.000 0.741 0.259
L44 Other papulosquamous disorders
0.000 0.744 0.256
L41 Parapsoriasis
0.000 0.744 0.256
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.744 0.256
L42 Pityriasis rosea
0.000 0.745 0.255
E07.9 Disorder of thyroid, unspecified
0.000 0.750 0.250
K51.4 Pseudopolyposis of colon
0.250 0.750 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.750 0.250
E61.1 Iron deficiency
0.000 0.754 0.246
K51.8 Other ulcerative colitis
0.243 0.757 0.000
E11.3 With ophthalmic complications
0.000 0.759 0.241
E89.0 Postprocedural hypothyroidism
0.000 0.760 0.240
K51.5 Mucosal proctocolitis
0.234 0.766 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.771 0.229
E61.8 Deficiency of other specified nutrient elements
0.000 0.771 0.229
E61.7 Deficiency of multiple nutrient elements
0.000 0.771 0.229
E61.6 Vanadium deficiency
0.000 0.771 0.229
E61.5 Molybdenum deficiency
0.000 0.771 0.229
E61.4 Chromium deficiency
0.000 0.771 0.229
E61.3 Manganese deficiency
0.000 0.771 0.229
E61.0 Copper deficiency
0.000 0.771 0.229
E50.9 Vitamin A deficiency, unspecified
0.000 0.777 0.223
E50.8 Other manifestations of vitamin A deficiency
0.000 0.777 0.223
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.777 0.223
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.777 0.223
E50.5 Vitamin A deficiency with night blindness
0.000 0.777 0.223
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.777 0.223
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.777 0.223
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.777 0.223
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.777 0.223
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.777 0.223
E63.9 Nutritional deficiency, unspecified
0.000 0.777 0.223
E63.8 Other specified nutritional deficiencies
0.000 0.777 0.223
E63.1 Imbalance of constituents of food intake
0.000 0.777 0.223
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.777 0.223
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.777 0.223
E64.8 Sequelae of other nutritional deficiencies
0.000 0.777 0.223
E64.3 Sequelae of rickets
0.000 0.777 0.223
E64.2 Sequelae of vitamin C deficiency
0.000 0.777 0.223
E64.1 Sequelae of vitamin A deficiency
0.000 0.777 0.223
E64.0 Sequelae of protein-energy malnutrition
0.000 0.777 0.223
E34.0 Carcinoid syndrome
0.001 0.777 0.222
E55.0 Rickets, active
0.000 0.779 0.220
E27.5 Adrenomedullary hyperfunction
0.000 0.780 0.220
E27.0 Other adrenocortical overactivity
0.000 0.780 0.220
E61.2 Magnesium deficiency
0.000 0.781 0.219
E51.9 Thiamine deficiency, unspecified
0.000 0.782 0.218
E51.8 Other manifestations of thiamine deficiency
0.000 0.782 0.218
E51.1 Beriberi
0.000 0.782 0.218
E11.2 With renal complications
0.001 0.782 0.217
E55.9 Vitamin D deficiency, unspecified
0.000 0.783 0.217
E83.3 Disorders of phosphorus metabolism
0.134 0.784 0.082
E56.9 Vitamin deficiency, unspecified
0.000 0.786 0.214
E56.8 Deficiency of other vitamins
0.000 0.786 0.214
E56.0 Deficiency of vitamin E
0.000 0.786 0.214
E23.0 Hypopituitarism
0.000 0.787 0.213
E51.2 Wernicke's encephalopathy
0.000 0.789 0.211
E07.8 Other specified disorders of thyroid
0.001 0.791 0.208
L43.8 Other lichen planus
0.000 0.792 0.208
E67 Other hyperalimentation
0.001 0.795 0.204
E68 Sequelae of hyperalimentation
0.001 0.795 0.204
L43.9 Lichen planus, unspecified
0.000 0.796 0.204
E56.1 Deficiency of vitamin K
0.000 0.799 0.201
L43.3 Subacute (active) lichen planus
0.000 0.803 0.197
L43.2 Lichenoid drug reaction
0.000 0.803 0.197
L43.1 Bullous lichen planus
0.000 0.803 0.197
L43.0 Hypertrophic lichen planus
0.000 0.803 0.197
I83.1 Varicose veins of lower extremities with inflammation
0.191 0.809 0.000
M45-M49 Spondylopathies
0.186 0.814 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.816 0.184
L41.8 Other parapsoriasis
0.000 0.816 0.184
L41.5 Retiform parapsoriasis
0.000 0.816 0.184
L41.4 Large plaque parapsoriasis
0.000 0.816 0.184
L41.3 Small plaque parapsoriasis
0.000 0.816 0.184
L41.2 Lymphomatoid papulosis
0.000 0.816 0.184
L41.1 Pityriasis lichenoides chronica
0.000 0.816 0.184
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.816 0.184
L44.9 Papulosquamous disorder, unspecified
0.000 0.816 0.184
L44.8 Other specified papulosquamous disorders
0.000 0.816 0.184
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.816 0.184
L44.3 Lichen ruber moniliformis
0.000 0.816 0.184
L44.2 Lichen striatus
0.000 0.816 0.184
L44.1 Lichen nitidus
0.000 0.816 0.184
L44.0 Pityriasis rubra pilaris
0.000 0.816 0.184
E20.9 Hypoparathyroidism, unspecified
0.001 0.816 0.183
K51.3 Ulcerative (chronic) rectosigmoiditis
0.183 0.817 0.000
E83.4 Disorders of magnesium metabolism
0.048 0.820 0.132
E27.1 Primary adrenocortical insufficiency
0.000 0.824 0.176
E29.1 Testicular hypofunction
0.000 0.826 0.174
K51.0 Ulcerative (chronic) enterocolitis
0.171 0.829 0.000
E53 Deficiency of other B group vitamins
0.000 0.833 0.166
K51.1 Ulcerative (chronic) ileocolitis
0.162 0.838 0.000
M48 Other spondylopathies
0.152 0.848 0.000
E67.8 Other specified hyperalimentation
0.001 0.853 0.147
E67.3 Hypervitaminosis D
0.001 0.853 0.147
E67.2 Megavitamin-B6 syndrome
0.001 0.853 0.147
E67.1 Hypercarotenaemia
0.001 0.853 0.147
E67.0 Hypervitaminosis A
0.001 0.853 0.147
E27.2 Addisonian crisis
0.001 0.856 0.144
E27.8 Other specified disorders of adrenal gland
0.000 0.862 0.137
M48.5 Collapsed vertebra, not elsewhere classified
0.137 0.863 0.000
E04 Other non-toxic goitre
0.000 0.871 0.129
E65 Localised adiposity
0.001 0.872 0.127
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.875 0.125
E11.4 With neurological complications
0.001 0.876 0.124
M46 Other inflammatory spondylopathies
0.122 0.878 0.000
E53.1 Pyridoxine deficiency
0.000 0.880 0.119
E53.0 Riboflavin deficiency
0.000 0.880 0.119
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.115 0.885 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.112 0.888 0.000
M49 Spondylopathies in diseases classified elsewhere
0.111 0.889 0.000
M48.9 Spondylopathy, unspecified
0.109 0.891 0.000
M48.4 Fatigue fracture of vertebra
0.109 0.891 0.000
M48.3 Traumatic spondylopathy
0.109 0.891 0.000
M48.2 Kissing spine
0.109 0.891 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.109 0.891 0.000
K51.2 Ulcerative (chronic) proctitis
0.107 0.893 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.895 0.105
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.103 0.897 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.102 0.898 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.102 0.898 0.000
M48.8 Other specified spondylopathies
0.102 0.898 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.099 0.901 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.099 0.901 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.099 0.901 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.099 0.901 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.099 0.901 0.000
E83.5 Disorders of calcium metabolism
0.022 0.905 0.074
M46.4 Discitis, unspecified
0.095 0.905 0.000
E04.8 Other specified non-toxic goitre
0.000 0.907 0.093
M46.0 Spinal enthesopathy
0.093 0.907 0.000
M48.0 Spinal stenosis
0.093 0.907 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.910 0.090
M46.2 Osteomyelitis of vertebra
0.088 0.911 0.000
M46.8 Other specified inflammatory spondylopathies
0.088 0.912 0.000
M46.5 Other infective spondylopathies
0.088 0.912 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.085 0.915 0.000
E80.4 Gilbert's syndrome
0.001 0.915 0.084
M48.02 Spinal stenosis (Cervical region)
0.085 0.915 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.081 0.919 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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