TreeWAS – Variant ID: rs9265759

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.122	0.878
L40.4 Guttate psoriasis	0.000	0.283	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.283	0.716
L40.2 Acrodermatitis continua	0.000	0.283	0.716
L40.1 Generalised pustular psoriasis	0.000	0.283	0.716
L40.8 Other psoriasis	0.000	0.322	0.678
E03 Other hypothyroidism	0.518	0.481	0.001
K90 Intestinal malabsorption	0.000	0.568	0.432
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.428	0.572	0.001
E03.5 Myxoedema coma	0.371	0.628	0.001
E03.4 Atrophy of thyroid (acquired)	0.371	0.628	0.001
E03.3 Postinfectious hypothyroidism	0.371	0.628	0.001
E03.1 Congenital hypothyroidism without goitre	0.371	0.628	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.371	0.628	0.001
L40-L45 Papulosquamous disorders	0.000	0.646	0.354
E03.8 Other specified hypothyroidism	0.349	0.651	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.667	0.333
K90.3 Pancreatic steatorrhoea	0.000	0.690	0.310
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.690	0.310
K90.1 Tropical sprue	0.000	0.690	0.310
K90.8 Other intestinal malabsorption	0.000	0.695	0.304
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.715	0.285
L44 Other papulosquamous disorders	0.000	0.746	0.254
L41 Parapsoriasis	0.000	0.746	0.254
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.746	0.254
L42 Pityriasis rosea	0.000	0.755	0.245
L43 Lichen planus	0.000	0.766	0.234
L41.9 Parapsoriasis, unspecified	0.000	0.818	0.182
L41.8 Other parapsoriasis	0.000	0.818	0.182
L41.5 Retiform parapsoriasis	0.000	0.818	0.182
L41.4 Large plaque parapsoriasis	0.000	0.818	0.182
L41.3 Small plaque parapsoriasis	0.000	0.818	0.182
L41.2 Lymphomatoid papulosis	0.000	0.818	0.182
L41.1 Pityriasis lichenoides chronica	0.000	0.818	0.182
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.818	0.182
L44.9 Papulosquamous disorder, unspecified	0.000	0.818	0.182
L44.8 Other specified papulosquamous disorders	0.000	0.818	0.182
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.818	0.182
L44.3 Lichen ruber moniliformis	0.000	0.818	0.182
L44.2 Lichen striatus	0.000	0.818	0.182
L44.1 Lichen nitidus	0.000	0.818	0.182
L44.0 Pityriasis rubra pilaris	0.000	0.818	0.182
L43.8 Other lichen planus	0.000	0.824	0.176
L43.3 Subacute (active) lichen planus	0.000	0.832	0.168
L43.2 Lichenoid drug reaction	0.000	0.832	0.168
L43.1 Bullous lichen planus	0.000	0.832	0.168
L43.0 Hypertrophic lichen planus	0.000	0.832	0.168
L43.9 Lichen planus, unspecified	0.000	0.865	0.135
M25.5 Pain in joint	0.000	0.885	0.115
M25.54 Pain in joint (Hand)	0.000	0.888	0.112
M25.51 Pain in joint (Shoulder region)	0.000	0.889	0.111
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.893	0.107
M25.59 Pain in joint (Site unspecified)	0.000	0.900	0.100
M25.58 Pain in joint (Other)	0.000	0.906	0.094
M25 Other joint disorders, not elsewhere classified	0.000	0.914	0.086
M25.50 Pain in joint (Multiple sites)	0.000	0.919	0.081
M25.57 Pain in joint (Ankle and foot)	0.000	0.921	0.079
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.922	0.078
M25.9 Joint disorder, unspecified	0.000	0.923	0.077
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.925	0.075
M25.53 Pain in joint (Forearm)	0.000	0.926	0.074
M25.52 Pain in joint (Upper arm)	0.000	0.928	0.072
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.929	0.071
M25.7 Osteophyte	0.000	0.931	0.069
I84.9 Unspecified haemorrhoids without complication	0.067	0.933	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.934	0.066
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.937	0.063
M25.2 Flail joint	0.000	0.938	0.062
M25.1 Fistula of joint	0.000	0.938	0.062
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.939	0.061
M25.71 Osteophyte (Shoulder region)	0.000	0.940	0.060
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.942	0.057
M25.0 Haemarthrosis	0.000	0.943	0.057
M25.77 Osteophyte (Ankle and foot)	0.000	0.943	0.057
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.943	0.057
M25.8 Other specified joint disorders	0.000	0.944	0.056
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.944	0.056
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.944	0.056
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.944	0.056
M25.74 Osteophyte (Hand)	0.000	0.944	0.056
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.944	0.056
M25.98 Joint disorder, unspecified (Other)	0.000	0.944	0.056
M25.94 Joint disorder, unspecified (Hand)	0.000	0.944	0.056
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.944	0.056
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.944	0.056
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.944	0.056
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.947	0.053
M25.3 Other instability of joint	0.000	0.947	0.053
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.947	0.053
M25.72 Osteophyte (Upper arm)	0.000	0.949	0.051
M25.84 Other specified joint disorders (Hand)	0.000	0.950	0.050
M25.79 Osteophyte (Site unspecified)	0.000	0.950	0.049
M25.73 Osteophyte (Forearm)	0.000	0.950	0.049
M25.70 Osteophyte (Multiple sites)	0.000	0.950	0.049
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.951	0.049
D12.8 Rectum	0.048	0.952	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.952	0.048
M25.4 Effusion of joint	0.000	0.953	0.047
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.953	0.046
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.955	0.045
M25.86 Other specified joint disorders (Lower leg)	0.000	0.955	0.044
M25.19 Fistula of joint (Site unspecified)	0.000	0.955	0.044
M25.18 Fistula of joint (Other)	0.000	0.955	0.044
M25.17 Fistula of joint (Ankle and foot)	0.000	0.955	0.044
M25.16 Fistula of joint (Lower leg)	0.000	0.955	0.044
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.955	0.044
M25.14 Fistula of joint (Hand)	0.000	0.955	0.044
M25.13 Fistula of joint (Forearm)	0.000	0.955	0.044
M25.12 Fistula of joint (Upper arm)	0.000	0.955	0.044
M25.11 Fistula of joint (Shoulder region)	0.000	0.955	0.044
M25.10 Fistula of joint (Multiple sites)	0.000	0.955	0.044
M25.29 Flail joint (Site unspecified)	0.000	0.955	0.044
M25.28 Flail joint (Other)	0.000	0.955	0.044
M25.27 Flail joint (Ankle and foot)	0.000	0.955	0.044
M25.26 Flail joint (Lower leg)	0.000	0.955	0.044
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.955	0.044
M25.24 Flail joint (Hand)	0.000	0.955	0.044
M25.23 Flail joint (Forearm)	0.000	0.955	0.044
M25.22 Flail joint (Upper arm)	0.000	0.955	0.044
M25.21 Flail joint (Shoulder region)	0.000	0.955	0.044
M25.20 Flail joint (Multiple sites)	0.000	0.955	0.044
M25.46 Effusion of joint (Lower leg)	0.000	0.959	0.041
M25.37 Other instability of joint (Ankle and foot)	0.000	0.959	0.041
M25.09 Haemarthrosis (Site unspecified)	0.000	0.959	0.041
M25.08 Haemarthrosis (Other)	0.000	0.959	0.041
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.959	0.041
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.959	0.041
M25.04 Haemarthrosis (Hand)	0.000	0.959	0.041
M25.03 Haemarthrosis (Forearm)	0.000	0.959	0.041
M25.02 Haemarthrosis (Upper arm)	0.000	0.959	0.041
M25.01 Haemarthrosis (Shoulder region)	0.000	0.959	0.041
M25.00 Haemarthrosis (Multiple sites)	0.000	0.959	0.041
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.960	0.040
M25.82 Other specified joint disorders (Upper arm)	0.000	0.960	0.040
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.960	0.040
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.960	0.040
M25.36 Other instability of joint (Lower leg)	0.000	0.961	0.039
M25.39 Other instability of joint (Site unspecified)	0.000	0.962	0.038
M25.38 Other instability of joint (Other)	0.000	0.962	0.038
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.962	0.038
M25.32 Other instability of joint (Upper arm)	0.000	0.962	0.038
M25.30 Other instability of joint (Multiple sites)	0.000	0.962	0.038
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.963	0.037
M25.43 Effusion of joint (Forearm)	0.000	0.963	0.037
M25.06 Haemarthrosis (Lower leg)	0.000	0.964	0.036
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.964	0.036
E00-E07 Disorders of thyroid gland	0.032	0.964	0.004
M25.83 Other specified joint disorders (Forearm)	0.000	0.964	0.035
K90-K93 Other diseases of the digestive system	0.000	0.965	0.035
M25.31 Other instability of joint (Shoulder region)	0.000	0.965	0.035
M25.49 Effusion of joint (Site unspecified)	0.000	0.966	0.034
M25.48 Effusion of joint (Other)	0.000	0.966	0.034
M25.41 Effusion of joint (Shoulder region)	0.000	0.966	0.034
M25.34 Other instability of joint (Hand)	0.000	0.966	0.034
M25.33 Other instability of joint (Forearm)	0.000	0.966	0.033
M25.88 Other specified joint disorders (Other)	0.000	0.968	0.032
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.969	0.031
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.969	0.031
D12.5 Sigmoid colon	0.030	0.970	0.000
M25.42 Effusion of joint (Upper arm)	0.000	0.970	0.030
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.030	0.970	0.000
M25.44 Effusion of joint (Hand)	0.000	0.971	0.029
M25.40 Effusion of joint (Multiple sites)	0.000	0.971	0.029
E07 Other disorders of thyroid	0.027	0.971	0.002
D12.4 Descending colon	0.028	0.972	0.000
D12.7 Rectosigmoid junction	0.028	0.972	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.023	0.974	0.003
E00 Congenital iodine-deficiency syndrome	0.023	0.974	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.023	0.974	0.003
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.974	0.025
M25.78 Osteophyte (Other)	0.000	0.975	0.025
E07.9 Disorder of thyroid, unspecified	0.024	0.976	0.000
S64.4 Injury of digital nerve of other finger	0.022	0.978	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.978	0.022
D12.2 Ascending colon	0.021	0.979	0.000
E07.1 Dyshormogenetic goitre	0.019	0.979	0.002
E07.0 Hypersecretion of calcitonin	0.019	0.979	0.002
D12.9 Anus and anal canal	0.019	0.980	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.017	0.981	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.017	0.981	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.017	0.981	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.017	0.981	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.017	0.981	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.017	0.981	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.017	0.981	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.017	0.981	0.002
E07.8 Other specified disorders of thyroid	0.017	0.981	0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.981	0.018
K93.1 Megacolon in Chagas' disease	0.000	0.981	0.018
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.981	0.018
D12.1 Appendix	0.018	0.982	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.982	0.018
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.982	0.018
D70 Agranulocytosis	0.000	0.983	0.017
S64 Injury of nerves at wrist and hand level	0.017	0.983	0.000
E06 Thyroiditis	0.013	0.983	0.004
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.984	0.016
C18.7 Sigmoid colon	0.016	0.984	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.984	0.016
E66.8 Other obesity	0.000	0.984	0.016
D75.2 Essential thrombocytosis	0.000	0.984	0.015
D72 Other disorders of white blood cells	0.000	0.985	0.015
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.985	0.015
D12.6 Colon, unspecified	0.015	0.985	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.986	0.014
D73 Diseases of spleen	0.000	0.986	0.014
S61.0 Open wound of finger(s) without damage to nail	0.014	0.986	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.014	0.986	0.000
D86 Sarcoidosis	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.000	0.987	0.013
S64.0 Injury of ulnar nerve at wrist and hand level	0.013	0.987	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.987	0.013
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.987	0.013
S64.2 Injury of radial nerve at wrist and hand level	0.013	0.987	0.000
D74 Methaemoglobinaemia	0.000	0.987	0.013
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.987	0.013
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.987	0.013
M20-M25 Other joint disorders	0.000	0.987	0.013
S60-S69 Injuries to the wrist and hand	0.013	0.987	0.000
S64.1 Injury of median nerve at wrist and hand level	0.013	0.987	0.000
D73.0 Hyposplenism	0.000	0.988	0.012
S61 Open wound of wrist and hand	0.012	0.988	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.988	0.012
S64.9 Injury of unspecified nerve at wrist and hand level	0.012	0.988	0.000
S64.8 Injury of other nerves at wrist and hand level	0.012	0.988	0.000
E06.5 Other chronic thyroiditis	0.009	0.988	0.003
E06.4 Drug-induced thyroiditis	0.009	0.988	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.009	0.988	0.003
E06.1 Subacute thyroiditis	0.009	0.988	0.003
E06.0 Acute thyroiditis	0.009	0.988	0.003
D75.0 Familial erythrocytosis	0.000	0.988	0.012
D86.0 Sarcoidosis of lung	0.000	0.988	0.012
S61.8 Open wound of other parts of wrist and hand	0.012	0.988	0.000
E66 Obesity	0.000	0.988	0.012
S60 Superficial injury of wrist and hand	0.012	0.988	0.000
M21 Other acquired deformities of limbs	0.000	0.988	0.012
S60.8 Other superficial injuries of wrist and hand	0.011	0.989	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.989	0.011
D72.9 Disorder of white blood cells, unspecified	0.000	0.989	0.011
D72.0 Genetic anomalies of leukocytes	0.000	0.989	0.011
M24 Other specific joint derangements	0.000	0.989	0.011
M31 Other necrotising vasculopathies	0.000	0.989	0.011
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.989	0.011
E66.0 Obesity due to excess calories	0.000	0.989	0.011
D73.9 Disease of spleen, unspecified	0.000	0.990	0.010
D73.8 Other diseases of spleen	0.000	0.990	0.010
D73.4 Cyst of spleen	0.000	0.990	0.010
D73.3 Abscess of spleen	0.000	0.990	0.010
D73.2 Chronic congestive splenomegaly	0.000	0.990	0.010
D73.1 Hypersplenism	0.000	0.990	0.010
M32 Systemic lupus erythematosus	0.000	0.990	0.010
M24.1 Other articular cartilage disorders	0.000	0.990	0.010
M21.1 Varus deformity, not elsewhere classified	0.000	0.990	0.010
D86.3 Sarcoidosis of skin	0.000	0.990	0.010
M21.3 Wrist or foot drop (acquired)	0.000	0.990	0.010
M24.0 Loose body in joint	0.000	0.990	0.010
S68 Traumatic amputation of wrist and hand	0.010	0.990	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.010	0.990	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.990	0.010
D76.3 Other histiocytosis syndromes	0.000	0.990	0.010
M31.6 Other giant cell arteritis	0.000	0.990	0.010
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.990	0.006
M34 Systemic sclerosis	0.000	0.990	0.010
S62 Fracture at wrist and hand level	0.010	0.990	0.000
C18 Malignant neoplasm of colon	0.010	0.990	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.990	0.010
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.990	0.010
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.990	0.010
M30 Polyarteritis nodosa and related conditions	0.000	0.990	0.010
D74.9 Methaemoglobinaemia, unspecified	0.000	0.990	0.009
D74.8 Other methaemoglobinaemias	0.000	0.990	0.009
D74.0 Congenital methaemoglobinaemia	0.000	0.990	0.009
D80-D89 Certain disorders involving the immune mechanism	0.000	0.990	0.009
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.990	0.009
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.009	0.991	0.000
D72.1 Eosinophilia	0.000	0.991	0.009
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.991	0.009
M21.0 Valgus deformity, not elsewhere classified	0.000	0.991	0.009
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.006	0.991	0.004
M24.02 Loose body in joint (Upper arm)	0.000	0.991	0.009
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.991	0.009
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.991	0.009
E06.3 Autoimmune thyroiditis	0.006	0.991	0.003
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.991	0.009
D73.5 Infarction of spleen	0.000	0.991	0.009
S65 Injury of blood vessels at wrist and hand level	0.009	0.991	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.009	0.991	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.991	0.009
M33 Dermatopolymyositis	0.000	0.991	0.009
C71.9 Brain, unspecified	0.009	0.991	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.991	0.009
S62.8 Fracture of other and unspecified parts of wrist and hand	0.009	0.991	0.000
E66.1 Drug-induced obesity	0.000	0.991	0.009
M24.01 Loose body in joint (Shoulder region)	0.000	0.991	0.009
C77.2 Intra-abdominal lymph nodes	0.009	0.991	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.991	0.009
S60.7 Multiple superficial injuries of wrist and hand	0.008	0.991	0.000
S60.1 Contusion of finger(s) with damage to nail	0.008	0.991	0.000
C18.6 Descending colon	0.009	0.991	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.009	0.991	0.000
M21.9 Acquired deformity of limb, unspecified	0.000	0.991	0.008
M21.8 Other specified acquired deformities of limbs	0.000	0.991	0.008
M21.7 Unequal limb length (acquired)	0.000	0.991	0.008
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.992	0.008
C18.0 Caecum	0.008	0.992	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.992	0.008
S62.7 Multiple fractures of fingers	0.008	0.992	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.008	0.992	0.000
M24.6 Ankylosis of joint	0.000	0.992	0.008
M24.9 Joint derangement, unspecified	0.000	0.992	0.008
M24.2 Disorder of ligament	0.000	0.992	0.008
C18.1 Appendix	0.008	0.992	0.000
S67 Crushing injury of wrist and hand	0.008	0.992	0.000
C18.5 Splenic flexure	0.008	0.992	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.992	0.008
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.992	0.008
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.008	0.992	0.000
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
I47.1 Supraventricular tachycardia	0.008	0.992	0.000
M31.8 Other specified necrotising vasculopathies	0.000	0.992	0.008
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.992	0.008
M31.2 Lethal midline granuloma	0.000	0.992	0.008
M31.1 Thrombotic microangiopathy	0.000	0.992	0.008
M31.0 Hypersensitivity angiitis	0.000	0.992	0.008
E65-E68 Obesity and other hyperalimentation	0.000	0.992	0.008
M21.6 Other acquired deformities of ankle and foot	0.000	0.992	0.008
C71 Malignant neoplasm of brain	0.008	0.992	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.992	0.008
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.992	0.008
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.992	0.008
E04 Other non-toxic goitre	0.007	0.992	0.001
I47.2 Ventricular tachycardia	0.008	0.992	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.992	0.008
M34.9 Systemic sclerosis, unspecified	0.000	0.992	0.008
D41.4 Bladder	0.008	0.992	0.000
I47 Paroxysmal tachycardia	0.008	0.992	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.992	0.008
M32.8 Other forms of systemic lupus erythematosus	0.000	0.992	0.008
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.992	0.008
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.008	0.992	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.992	0.008
M24.18 Other articular cartilage disorders (Other)	0.000	0.992	0.008
M24.14 Other articular cartilage disorders (Hand)	0.000	0.992	0.008
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.992	0.008
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.992	0.008
S62.5 Fracture of thumb	0.008	0.992	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.992	0.008
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.992	0.008
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.992	0.008
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.992	0.008
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.992	0.008
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.992	0.008
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.992	0.008
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.992	0.008
D12.0 Caecum	0.008	0.992	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.992	0.007
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.992	0.007
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.992	0.007
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.992	0.007
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.992	0.007
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.992	0.007
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.992	0.007
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.992	0.007
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.992	0.007
M31.3 Wegener's granulomatosis	0.000	0.992	0.007
M24.09 Loose body in joint (Site unspecified)	0.000	0.992	0.007
M24.08 Loose body in joint (Other)	0.000	0.992	0.007
M24.06 Loose body in joint-Lower leg	0.000	0.992	0.007
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.992	0.007
M24.04 Loose body in joint (Hand)	0.000	0.992	0.007
M24.03 Loose body in joint (Forearm)	0.000	0.992	0.007
M24.00 Loose body in joint (Multiple sites)	0.000	0.992	0.007
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.992	0.007
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.992	0.007
R63.0 Anorexia	0.000	0.992	0.008
C18.3 Hepatic flexure	0.007	0.992	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.992	0.007
C18.2 Ascending colon	0.007	0.993	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.993	0.007
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.007	0.993	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.007	0.993	0.000
S68.4 Traumatic amputation of hand at wrist level	0.007	0.993	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.007	0.993	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.007	0.993	0.000
C71.2 Temporal lobe	0.007	0.993	0.000
M35 Other systemic involvement of connective tissue	0.000	0.993	0.007
S62.70 Multiple fractures of fingers (closed)	0.007	0.993	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.993	0.007
E05.8 Other thyrotoxicosis	0.003	0.993	0.004
E05.5 Thyroid crisis or storm	0.003	0.993	0.004
E05.4 Thyrotoxicosis factitia	0.003	0.993	0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.993	0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.993	0.004
S62.4 Multiple fractures of metacarpal bones	0.007	0.993	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.993	0.007
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.993	0.007
M34.0 Progressive systemic sclerosis	0.000	0.993	0.007
S62.1 Fracture of other carpal bone(s)	0.007	0.993	0.000
M24.7 Protrusio acetabuli	0.000	0.993	0.007
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.993	0.007
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.993	0.007
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.993	0.007
M30.2 Juvenile polyarteritis	0.000	0.993	0.007
C18.8 Overlapping lesion of colon	0.007	0.993	0.000
S64.3 Injury of digital nerve of thumb	0.007	0.993	0.000
S60.2 Contusion of other parts of wrist and hand	0.007	0.993	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.993	0.007
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.993	0.007
S60.0 Contusion of finger(s) without damage to nail	0.007	0.993	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.007	0.993	0.000
S63.0 Dislocation of wrist	0.007	0.993	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.993	0.007
S63.5 Sprain and strain of wrist	0.007	0.993	0.000
M31.7 Microscopic polyangiitis	0.000	0.993	0.007
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.993	0.007
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.993	0.007
M36.3 Arthropathy in other blood disorders	0.000	0.993	0.007
M36.2 Haemophilic arthropathy	0.000	0.993	0.007
M36.1 Arthropathy in neoplastic disease	0.000	0.993	0.007
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.993	0.007
D82 Immunodeficiency associated with other major defects	0.000	0.993	0.007
D81 Combined immunodeficiencies	0.000	0.993	0.007
S63.1 Dislocation finger	0.007	0.993	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.007	0.993	0.000
S63.2 Multiple dislocations of fingers	0.007	0.993	0.000
S62.3 Fracture of other metacarpal bone	0.007	0.993	0.000
S65.1 Injury of radial artery at wrist and hand level	0.007	0.993	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.993	0.007
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.993	0.007
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.993	0.007
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.993	0.007
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.993	0.007
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.993	0.007
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.993	0.007
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.993	0.007
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.993	0.007
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.007	0.993	0.000
M21.2 Flexion deformity	0.000	0.993	0.007
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.993	0.005
M33.2 Polymyositis	0.000	0.993	0.007
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.007	0.993	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.993	0.007
S66.8 Injury of other muscles and tendons at wrist and hand level	0.007	0.993	0.000
E65 Localised adiposity	0.000	0.993	0.007
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.993	0.007
M34.1 CR(E)ST syndrome	0.000	0.993	0.007
D83 Common variable immunodeficiency	0.000	0.993	0.007
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.007	0.993	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.007	0.993	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.007	0.993	0.000
S65.5 Injury of blood vessel(s) of other finger	0.007	0.993	0.000
S65.4 Injury of blood vessel(s) of thumb	0.007	0.993	0.000
S65.3 Injury of deep palmar arch	0.007	0.993	0.000
S65.2 Injury of superficial palmar arch	0.007	0.993	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.993	0.007
M33.9 Dermatopolymyositis, unspecified	0.000	0.993	0.006
M33.0 Juvenile dermatomyositis	0.000	0.993	0.006
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.007	0.993	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
S69 Other and unspecified injuries of wrist and hand	0.006	0.993	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.993	0.007
S62.2 Fracture of first metacarpal bone	0.006	0.993	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.993	0.006
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.993	0.006
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.993	0.006
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.993	0.006
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.993	0.006
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.993	0.006
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.993	0.006
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.993	0.006
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.993	0.006
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.006	0.993	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.007	0.993	0.000
S62.50 Fracture of thumb (closed)	0.007	0.993	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.993	0.006
K91.1 Postgastric surgery syndromes	0.000	0.993	0.006
M24.21 Disorder of ligament (Shoulder region)	0.000	0.993	0.006
S61.7 Multiple open wounds of wrist and hand	0.006	0.994	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.994	0.006
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.006	0.994	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.006	0.994	0.000
D84 Other immunodeficiencies	0.000	0.994	0.006
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.994	0.006
M21.78 Unequal limb length (acquired)-Other	0.000	0.994	0.006
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.994	0.006
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.994	0.006
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.994	0.006
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.994	0.006
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.994	0.006
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.994	0.006
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.994	0.006
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.994	0.006
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.994	0.006
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations