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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267404
log Bayes Factor = 64.1434
Chromosome 6   position 31,470,545  (GRCh37) Explore rs9267404 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.997 0.003 0.000
R31 Unspecified haematuria
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.007 0.993
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
E00-E07 Disorders of thyroid gland
0.000 0.012 0.988
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.019 0.981
E10.2 With renal complications
0.000 0.024 0.976
E10.9 Without complications
0.000 0.030 0.970
E10.3 With ophthalmic complications
0.000 0.042 0.958
M45.X2 Ankylosing spondylitis (Cervical region)
0.951 0.049 0.000
G35 Multiple sclerosis
0.000 0.051 0.949
E10.1 With ketoacidosis
0.000 0.065 0.935
K90 Intestinal malabsorption
0.000 0.075 0.925
I25 Chronic ischaemic heart disease
0.922 0.078 0.000
I20-I25 Ischaemic heart diseases
0.917 0.083 0.000
I20 Angina pectoris
0.917 0.083 0.000
I25.1 Atherosclerotic heart disease
0.917 0.083 0.000
E10.4 With neurological complications
0.000 0.085 0.915
I20.0 Unstable angina
0.910 0.090 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.092 0.908
K90.9 Intestinal malabsorption, unspecified
0.000 0.094 0.906
E27 Other disorders of adrenal gland
0.000 0.098 0.902
E50-E64 Other nutritional deficiencies
0.000 0.103 0.897
E27.1 Primary adrenocortical insufficiency
0.000 0.118 0.882
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.129 0.871
I24 Other acute ischaemic heart diseases
0.869 0.131 0.000
I20.9 Angina pectoris, unspecified
0.864 0.136 0.000
E10.8 With unspecified complications
0.000 0.138 0.862
G37 Other demyelinating diseases of central nervous system
0.000 0.143 0.857
E05.8 Other thyrotoxicosis
0.000 0.147 0.853
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.151 0.849
I25.9 Chronic ischaemic heart disease, unspecified
0.848 0.152 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.841 0.159 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.164 0.836
I25.5 Ischaemic cardiomyopathy
0.830 0.170 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.826 0.174 0.000
E06 Thyroiditis
0.000 0.185 0.815
E10.5 With peripheral circulatory complications
0.000 0.188 0.812
E10.6 With other specified complications
0.000 0.190 0.810
E53 Deficiency of other B group vitamins
0.000 0.192 0.808
I20.1 Angina pectoris with documented spasm
0.808 0.192 0.000
E11.5 With peripheral circulatory complications
0.000 0.198 0.802
E27.8 Other specified disorders of adrenal gland
0.000 0.201 0.799
E61 Deficiency of other nutrient elements
0.000 0.210 0.790
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.233 0.767
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.245 0.755
I25.2 Old myocardial infarction
0.746 0.254 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.265 0.735
E34 Other endocrine disorders
0.000 0.266 0.734
I23 Certain current complications following acute myocardial infarction
0.734 0.266 0.000
E20 Hypoparathyroidism
0.000 0.268 0.732
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.270 0.730
I24.8 Other forms of acute ischaemic heart disease
0.728 0.272 0.000
E27.2 Addisonian crisis
0.000 0.273 0.727
E06.9 Thyroiditis, unspecified
0.000 0.279 0.721
E53.8 Deficiency of other specified B group vitamins
0.000 0.282 0.718
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E10.7 With multiple complications
0.000 0.284 0.716
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.709
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.709
E14 Unspecified diabetes mellitus
0.000 0.295 0.705
I25.4 Coronary artery aneurysm
0.690 0.310 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.690 0.310 0.000
E61.1 Iron deficiency
0.000 0.315 0.685
E40-E46 Malnutrition
0.000 0.320 0.679
I25.6 Silent myocardial ischaemia
0.673 0.327 0.000
E11.4 With neurological complications
0.000 0.327 0.673
E07 Other disorders of thyroid
0.000 0.330 0.670
E11.3 With ophthalmic complications
0.000 0.332 0.668
K90.3 Pancreatic steatorrhoea
0.000 0.336 0.663
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.336 0.663
K90.1 Tropical sprue
0.000 0.336 0.663
E11.6 With other specified complications
0.000 0.338 0.662
K90.8 Other intestinal malabsorption
0.000 0.348 0.652
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.349 0.651
E32 Diseases of thymus
0.000 0.349 0.651
E31 Polyglandular dysfunction
0.000 0.349 0.651
E30 Disorders of puberty, not elsewhere classified
0.000 0.349 0.651
E51 Thiamine deficiency
0.000 0.353 0.647
E27.5 Adrenomedullary hyperfunction
0.000 0.353 0.647
E27.0 Other adrenocortical overactivity
0.000 0.353 0.647
E25 Adrenogenital disorders
0.000 0.355 0.645
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.356 0.643
E63 Other nutritional deficiencies
0.000 0.356 0.643
E50 Vitamin A deficiency
0.000 0.356 0.643
E60 Dietary zinc deficiency
0.000 0.356 0.643
E59 Dietary selenium deficiency
0.000 0.356 0.643
E54 Ascorbic acid deficiency
0.000 0.356 0.643
E52 Niacin deficiency [pellagra]
0.000 0.356 0.643
E53.9 Vitamin B deficiency, unspecified
0.000 0.357 0.643
E10.0 With coma
0.000 0.364 0.636
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.370 0.630
I24.9 Acute ischaemic heart disease, unspecified
0.629 0.371 0.000
E61.2 Magnesium deficiency
0.000 0.374 0.626
E56 Other vitamin deficiencies
0.000 0.384 0.616
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.385 0.615
G37.5 Concentric sclerosis [Balo]
0.000 0.386 0.614
G37.4 Subacute necrotising myelitis
0.000 0.386 0.614
G37.2 Central pontine myelinolysis
0.000 0.386 0.614
G37.1 Central demyelination of corpus callosum
0.000 0.386 0.614
G37.0 Diffuse sclerosis
0.000 0.386 0.614
G36 Other acute disseminated demyelination
0.000 0.391 0.609
E20.9 Hypoparathyroidism, unspecified
0.000 0.393 0.607
I23.8 Other current complications following acute myocardial infarction
0.602 0.398 0.000
E11.1 With ketoacidosis
0.000 0.400 0.600
E11.7 With multiple complications
0.000 0.401 0.599
E34.9 Endocrine disorder, unspecified
0.000 0.401 0.599
I25.3 Aneurysm of heart
0.590 0.410 0.000
E14.3 With ophthalmic complications
0.000 0.411 0.589
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.412 0.588
E06.4 Drug-induced thyroiditis
0.000 0.415 0.584
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.415 0.584
E06.1 Subacute thyroiditis
0.000 0.415 0.584
E06.0 Acute thyroiditis
0.000 0.415 0.584
E11.8 With unspecified complications
0.000 0.417 0.583
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.419 0.581
E58 Dietary calcium deficiency
0.000 0.419 0.580
E55 Vitamin D deficiency
0.000 0.420 0.580
E53.1 Pyridoxine deficiency
0.000 0.421 0.579
E53.0 Riboflavin deficiency
0.000 0.421 0.579
E21.0 Primary hyperparathyroidism
0.000 0.422 0.578
E27.9 Disorder of adrenal gland, unspecified
0.000 0.432 0.568
E61.9 Deficiency of nutrient element, unspecified
0.000 0.434 0.566
E61.8 Deficiency of other specified nutrient elements
0.000 0.434 0.566
E61.7 Deficiency of multiple nutrient elements
0.000 0.434 0.566
E61.6 Vanadium deficiency
0.000 0.434 0.566
E61.5 Molybdenum deficiency
0.000 0.434 0.566
E61.4 Chromium deficiency
0.000 0.434 0.566
E61.3 Manganese deficiency
0.000 0.434 0.566
E61.0 Copper deficiency
0.000 0.434 0.566
E14.1 With ketoacidosis
0.000 0.436 0.564
E06.3 Autoimmune thyroiditis
0.000 0.447 0.553
E29 Testicular dysfunction
0.000 0.447 0.552
E14.5 With peripheral circulatory complications
0.000 0.448 0.552
E06.5 Other chronic thyroiditis
0.000 0.452 0.547
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.453 0.547
E13 Other specified diabetes mellitus
0.000 0.456 0.543
E34.8 Other specified endocrine disorders
0.000 0.461 0.539
E26 Hyperaldosteronism
0.000 0.466 0.534
E24 Cushing's syndrome
0.000 0.467 0.533
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.468 0.532
E34.0 Carcinoid syndrome
0.000 0.470 0.530
E34.5 Androgen resistance syndrome
0.000 0.474 0.526
E34.4 Constitutional tall stature
0.000 0.474 0.526
E34.3 Short stature, not elsewhere classified
0.000 0.474 0.526
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.474 0.526
E34.1 Other hypersecretion of intestinal hormones
0.000 0.474 0.526
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.526 0.474 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.526 0.474 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.526 0.474 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.526 0.474 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.526 0.474 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.526 0.474 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.526 0.474 0.000
E20.8 Other hypoparathyroidism
0.000 0.475 0.525
E20.1 Pseudohypoparathyroidism
0.000 0.475 0.525
E20.0 Idiopathic hypoparathyroidism
0.000 0.475 0.525
E14.6 With other specified complications
0.000 0.476 0.524
E21.4 Other specified disorders of parathyroid gland
0.000 0.476 0.523
E14.8 With unspecified complications
0.000 0.480 0.520
I25.0 Atherosclerotic cardiovascular disease, so described
0.516 0.484 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.487 0.513
I24.1 Dressler's syndrome
0.511 0.489 0.000
E12.9 Without complications
0.000 0.489 0.510
E12.8 With unspecified complications
0.000 0.489 0.510
E12.7 With multiple complications
0.000 0.489 0.510
E12.6 With other specified complications
0.000 0.489 0.510
E12.5 With peripheral circulatory complications
0.000 0.489 0.510
E12.4 With neurological complications
0.000 0.489 0.510
E12.3 With ophthalmic complications
0.000 0.489 0.510
E12.2 With renal complications
0.000 0.489 0.510
E12.1 With ketoacidosis
0.000 0.489 0.510
E12.0 With coma
0.000 0.489 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
E14.7 With multiple complications
0.000 0.494 0.505
E14.2 Withrenal complications
0.000 0.494 0.505
E14.0 With coma
0.000 0.494 0.505
E21.2 Other hyperparathyroidism
0.000 0.500 0.500
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.513 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.513 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.513 0.487
E42 Marasmic kwashiorkor
0.000 0.513 0.487
E41 Nutritional marasmus
0.000 0.513 0.487
E40 Kwashiorkor
0.000 0.513 0.487
E07.1 Dyshormogenetic goitre
0.000 0.519 0.480
E07.0 Hypersecretion of calcitonin
0.000 0.519 0.480
E14.4 With neurological complications
0.000 0.525 0.475
E11.2 With renal complications
0.000 0.531 0.469
E51.2 Wernicke's encephalopathy
0.000 0.532 0.468
E30.9 Disorder of puberty, unspecified
0.000 0.533 0.467
E30.8 Other disorders of puberty
0.000 0.533 0.467
E30.1 Precocious puberty
0.000 0.533 0.467
E30.0 Delayed puberty
0.000 0.533 0.467
E31.9 Polyglandular dysfunction, unspecified
0.000 0.533 0.467
E31.8 Other polyglandular dysfunction
0.000 0.533 0.467
E31.1 Polyglandular hyperfunction
0.000 0.533 0.467
E31.0 Autoimmune polyglandular failure
0.000 0.533 0.467
E32.9 Disease of thymus, unspecified
0.000 0.533 0.467
E32.8 Other diseases of thymus
0.000 0.533 0.467
E32.1 Abscess of thymus
0.000 0.533 0.467
E32.0 Persistent hyperplasia of thymus
0.000 0.533 0.467
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.533 0.467
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.533 0.467
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.533 0.467
E51.9 Thiamine deficiency, unspecified
0.000 0.536 0.464
E51.8 Other manifestations of thiamine deficiency
0.000 0.536 0.464
E51.1 Beriberi
0.000 0.536 0.464
E25.9 Adrenogenital disorder, unspecified
0.000 0.537 0.462
E25.8 Other adrenogenital disorders
0.000 0.537 0.462
E50.9 Vitamin A deficiency, unspecified
0.000 0.538 0.461
E50.8 Other manifestations of vitamin A deficiency
0.000 0.538 0.461
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.538 0.461
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.538 0.461
E50.5 Vitamin A deficiency with night blindness
0.000 0.538 0.461
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.538 0.461
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.538 0.461
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.538 0.461
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.538 0.461
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.538 0.461
E63.9 Nutritional deficiency, unspecified
0.000 0.538 0.461
E63.8 Other specified nutritional deficiencies
0.000 0.538 0.461
E63.1 Imbalance of constituents of food intake
0.000 0.538 0.461
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.538 0.461
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.538 0.461
E64.8 Sequelae of other nutritional deficiencies
0.000 0.538 0.461
E64.3 Sequelae of rickets
0.000 0.538 0.461
E64.2 Sequelae of vitamin C deficiency
0.000 0.538 0.461
E64.1 Sequelae of vitamin A deficiency
0.000 0.538 0.461
E64.0 Sequelae of protein-energy malnutrition
0.000 0.538 0.461
E46 Unspecified protein-energy malnutrition
0.000 0.542 0.458
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.543 0.457
I22 Subsequent myocardial infarction
0.448 0.552 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.558 0.442
E56.8 Deficiency of other vitamins
0.000 0.558 0.442
E56.0 Deficiency of vitamin E
0.000 0.558 0.442
E21.3 Hyperparathyroidism, unspecified
0.000 0.561 0.439
I21 Acute myocardial infarction
0.439 0.561 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.563 0.437
G36.8 Other specified acute disseminated demyelination
0.000 0.563 0.437
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.563 0.437
R30.0 Dysuria
0.436 0.564 0.000
R30-R39 Symptoms and signs involving the urinary system
0.431 0.569 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.431 0.569 0.000
R30 Pain associated with micturition
0.430 0.570 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.579 0.421
E55.0 Rickets, active
0.000 0.584 0.416
E56.1 Deficiency of vitamin K
0.000 0.586 0.414
E28 Ovarian dysfunction
0.000 0.588 0.412
I22.1 Subsequent myocardial infarction of inferior wall
0.402 0.598 0.000
R34 Anuria and oliguria
0.398 0.602 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.604 0.396
E29.8 Other testicular dysfunction
0.000 0.604 0.396
E29.0 Testicular hyperfunction
0.000 0.604 0.396
E07.8 Other specified disorders of thyroid
0.000 0.606 0.394
E15 Nondiabetic hypoglycaemic coma
0.000 0.608 0.392
E13.8 With unspecified complications
0.000 0.610 0.390
E13.7 With multiple complications
0.000 0.610 0.390
E13.6 With other specified complications
0.000 0.610 0.390
E13.5 With peripheral circulatory complications
0.000 0.610 0.390
E13.4 With neurological complications
0.000 0.610 0.390
E13.2 With renal complications
0.000 0.610 0.390
E13.1 With ketoacidosis
0.000 0.610 0.390
E13.0 With coma
0.000 0.610 0.390
E13.3 With ophthalmic complications
0.000 0.611 0.389
E26.8 Other hyperaldosteronism
0.000 0.617 0.383
E26.1 Secondary hyperaldosteronism
0.000 0.617 0.383
E11.0 With coma
0.000 0.617 0.382
E24.8 Other Cushing's syndrome
0.000 0.617 0.382
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.617 0.382
E24.3 Ectopic ACTH syndrome
0.000 0.617 0.382
E24.1 Nelson's syndrome
0.000 0.617 0.382
E22 Hyperfunction of pituitary gland
0.000 0.622 0.378
E24.0 Pituitary-dependent Cushing's disease
0.000 0.631 0.369
E26.9 Hyperaldosteronism, unspecified
0.000 0.633 0.367
E24.2 Drug-induced Cushing's syndrome
0.000 0.645 0.355
E55.9 Vitamin D deficiency, unspecified
0.000 0.648 0.352
E44.1 Mild protein-energy malnutrition
0.000 0.650 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.650 0.349
E24.9 Cushing's syndrome, unspecified
0.000 0.676 0.324
E65-E68 Obesity and other hyperalimentation
0.000 0.679 0.321
I21.X Presumed acute myicardial infaction (unconfirmed)
0.315 0.685 0.000
R30.1 Vesical tenesmus
0.312 0.688 0.000
I21.9 Acute myocardial infarction, unspecified
0.307 0.693 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.701 0.298
E29.1 Testicular hypofunction
0.000 0.702 0.298
E28.9 Ovarian dysfunction, unspecified
0.000 0.704 0.296
E28.8 Other ovarian dysfunction
0.000 0.704 0.296
E28.1 Androgen excess
0.000 0.704 0.296
E28.0 Oestrogen excess
0.000 0.704 0.296
E26.0 Primary hyperaldosteronism
0.000 0.708 0.292
E03 Other hypothyroidism
0.001 0.711 0.289
R36 Urethral discharge
0.283 0.717 0.000
E28.3 Primary ovarian failure
0.000 0.728 0.271
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.729 0.271
E22.8 Other hyperfunction of pituitary gland
0.000 0.729 0.271
I20.8 Other forms of angina pectoris
0.255 0.745 0.000
I22.8 Subsequent myocardial infarction of other sites
0.252 0.748 0.000
E22.1 Hyperprolactinaemia
0.000 0.763 0.237
E16 Other disorders of pancreatic internal secretion
0.000 0.770 0.230
E67 Other hyperalimentation
0.000 0.770 0.230
E68 Sequelae of hyperalimentation
0.000 0.770 0.230
E13.9 Without complications
0.000 0.777 0.223
E23.7 Disorder of pituitary gland, unspecified
0.000 0.778 0.221
I21.3 Acute transmural myocardial infarction of unspecified site
0.221 0.778 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.786 0.214
E23.1 Drug-induced hypopituitarism
0.000 0.786 0.214
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.787 0.213
E22.0 Acromegaly and pituitary gigantism
0.000 0.790 0.210
E03.5 Myxoedema coma
0.001 0.792 0.207
E03.4 Atrophy of thyroid (acquired)
0.001 0.792 0.207
E03.3 Postinfectious hypothyroidism
0.001 0.792 0.207
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.792 0.207
E03.1 Congenital hypothyroidism without goitre
0.001 0.796 0.203
I22.0 Subsequent myocardial infarction of anterior wall
0.198 0.802 0.000
M25.54 Pain in joint (Hand)
0.000 0.802 0.198
M25.5 Pain in joint
0.000 0.802 0.198
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.805 0.195
E03.8 Other specified hypothyroidism
0.000 0.810 0.190
R30.9 Painful micturition, unspecified
0.190 0.810 0.000
E23.2 Diabetes insipidus
0.000 0.817 0.183
E04 Other non-toxic goitre
0.000 0.823 0.177
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.823 0.176
M25.53 Pain in joint (Forearm)
0.000 0.824 0.176
M25.58 Pain in joint (Other)
0.000 0.828 0.172
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.835 0.165
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.835 0.165
E16.4 Abnormal secretion of gastrin
0.000 0.835 0.165
E16.3 Increased secretion of glucagon
0.000 0.835 0.165
E67.8 Other specified hyperalimentation
0.000 0.835 0.165
E67.3 Hypervitaminosis D
0.000 0.835 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.835 0.165
E67.1 Hypercarotenaemia
0.000 0.835 0.165
E67.0 Hypervitaminosis A
0.000 0.835 0.165
M25 Other joint disorders, not elsewhere classified
0.000 0.836 0.164
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.838 0.162
M25.7 Osteophyte
0.000 0.843 0.157
I21.1 Acute transmural myocardial infarction of inferior wall
0.155 0.845 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.000 0.846 0.154
E65 Localised adiposity
0.000 0.850 0.150
M25.71 Osteophyte (Shoulder region)
0.000 0.856 0.144
I22.9 Subsequent myocardial infarction of unspecified site
0.143 0.857 0.000
E16.1 Other hypoglycaemia
0.000 0.858 0.142
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.858 0.142
E11.9 Without complications
0.000 0.859 0.141
E23.6 Other disorders of pituitary gland
0.001 0.861 0.138
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.861 0.138
M25.9 Joint disorder, unspecified
0.000 0.862 0.138
R39 Other symptoms and signs involving the urinary system
0.136 0.864 0.000
M25.72 Osteophyte (Upper arm)
0.000 0.867 0.133
E04.0 Non-toxic diffuse goitre
0.000 0.867 0.133
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.868 0.132
M25.77 Osteophyte (Ankle and foot)
0.000 0.869 0.131
M25.52 Pain in joint (Upper arm)
0.000 0.870 0.130
M25.76 Osteophyte (Lower leg)
0.000 0.871 0.129
E04.8 Other specified non-toxic goitre
0.000 0.873 0.127
M25.74 Osteophyte (Hand)
0.000 0.876 0.124
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.876 0.124
M25.50 Pain in joint (Multiple sites)
0.000 0.877 0.123
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.000 0.877 0.123
M25.96 Joint disorder, unspecified (Lower leg)
0.000 0.878 0.122
M25.0 Haemarthrosis
0.000 0.878 0.122
M25.73 Osteophyte (Forearm)
0.000 0.879 0.120
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.882 0.118
E28.2 Polycystic ovarian syndrome
0.001 0.882 0.118
M25.2 Flail joint
0.000 0.882 0.118
M25.1 Fistula of joint
0.000 0.882 0.118
M25.57 Pain in joint (Ankle and foot)
0.000 0.883 0.117
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.884 0.116
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.885 0.115
E23.0 Hypopituitarism
0.000 0.886 0.114
H20.9 Iridocyclitis, unspecified
0.113 0.887 0.000
C71 Malignant neoplasm of brain
0.113 0.887 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.113 0.887 0.000
M25.70 Osteophyte (Multiple sites)
0.000 0.887 0.113
M25.79 Osteophyte (Site unspecified)
0.000 0.888 0.112
E16.2 Hypoglycaemia, unspecified
0.000 0.889 0.111
C71.9 Brain, unspecified
0.111 0.889 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.000 0.889 0.111
C71.2 Temporal lobe
0.111 0.889 0.000
M25.59 Pain in joint (Site unspecified)
0.000 0.890 0.110
C71.0 Cerebrum, except lobes and ventricles
0.107 0.893 0.000
M25.94 Joint disorder, unspecified (Hand)
0.000 0.895 0.105
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.000 0.896 0.104
M25.98 Joint disorder, unspecified (Other)
0.000 0.901 0.099
M25.92 Joint disorder, unspecified (Upper arm)
0.000 0.901 0.099
M25.90 Joint disorder, unspecified (Multiple sites)
0.000 0.901 0.099
M25.78 Osteophyte (Other)
0.000 0.902 0.098
R39.2 Extrarenal uraemia
0.098 0.902 0.000
C71.3 Parietal lobe
0.096 0.904 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.000 0.904 0.095
M25.93 Joint disorder, unspecified (Forearm)
0.000 0.905 0.095
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.000 0.906 0.094
R39.0 Extravasation of urine
0.091 0.909 0.000
M25.06 Haemarthrosis (Lower leg)
0.000 0.909 0.091
M25.09 Haemarthrosis (Site unspecified)
0.000 0.913 0.087
M25.08 Haemarthrosis (Other)
0.000 0.913 0.087
M25.07 Haemarthrosis (Ankle and foot)
0.000 0.913 0.087
M25.05 Haemarthrosis (Pelvic region and thigh)
0.000 0.913 0.087
M25.04 Haemarthrosis (Hand)
0.000 0.913 0.087
M25.03 Haemarthrosis (Forearm)
0.000 0.913 0.087
M25.02 Haemarthrosis (Upper arm)
0.000 0.913 0.087
M25.01 Haemarthrosis (Shoulder region)
0.000 0.913 0.087
M25.00 Haemarthrosis (Multiple sites)
0.000 0.913 0.087
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.914 0.086
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.914 0.086
M25.19 Fistula of joint (Site unspecified)
0.000 0.915 0.085
M25.18 Fistula of joint (Other)
0.000 0.915 0.085
M25.17 Fistula of joint (Ankle and foot)
0.000 0.915 0.085
M25.16 Fistula of joint (Lower leg)
0.000 0.915 0.085
M25.15 Fistula of joint (Pelvic region and thigh)
0.000 0.915 0.085
M25.14 Fistula of joint (Hand)
0.000 0.915 0.085
M25.13 Fistula of joint (Forearm)
0.000 0.915 0.085
M25.12 Fistula of joint (Upper arm)
0.000 0.915 0.085
M25.11 Fistula of joint (Shoulder region)
0.000 0.915 0.085
M25.10 Fistula of joint (Multiple sites)
0.000 0.915 0.085
M25.29 Flail joint (Site unspecified)
0.000 0.915 0.085
M25.28 Flail joint (Other)
0.000 0.915 0.085
M25.27 Flail joint (Ankle and foot)
0.000 0.915 0.085
M25.26 Flail joint (Lower leg)
0.000 0.915 0.085
M25.25 Flail joint (Pelvic region and thigh)
0.000 0.915 0.085
M25.24 Flail joint (Hand)
0.000 0.915 0.085
M25.23 Flail joint (Forearm)
0.000 0.915 0.085
M25.22 Flail joint (Upper arm)
0.000 0.915 0.085
M25.21 Flail joint (Shoulder region)
0.000 0.915 0.085
M25.20 Flail joint (Multiple sites)
0.000 0.915 0.085
M25.97 Joint disorder, unspecified (Ankle and foot)
0.000 0.917 0.082
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.083 0.917 0.000
C71.7 Brain stem
0.081 0.919 0.000
C71.6 Cerebellum
0.081 0.919 0.000
C71.5 Cerebral ventricle
0.081 0.919 0.000
C71.8 Overlapping lesion of brain
0.081 0.919 0.000
C71.4 Occipital lobe
0.076 0.924 0.000
R32 Unspecified urinary incontinence
0.073 0.927 0.000
S02.4 Fracture of malar and maxillary bones
0.000 0.930 0.070
E04.2 Non-toxic multinodular goitre
0.000 0.930 0.070
E66 Obesity
0.000 0.934 0.066
C71.1 Frontal lobe
0.066 0.934 0.000
K90-K93 Other diseases of the digestive system
0.000 0.935 0.064
I21.4 Acute subendocardial myocardial infarction
0.063 0.937 0.000
M25.3 Other instability of joint
0.000 0.940 0.060
S02 Fracture of skull and facial bones
0.000 0.942 0.058
E04.9 Non-toxic goitre, unspecified
0.000 0.943 0.057
M45-M49 Spondylopathies
0.057 0.943 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.055 0.945 0.000
M25.8 Other specified joint disorders
0.000 0.945 0.055
S06 Intracranial injury
0.000 0.946 0.054
S00-S09 Injuries to the head
0.000 0.947 0.053
E04.1 Non-toxic single thyroid nodule
0.000 0.949 0.051
S02.6 Fracture of mandible
0.000 0.949 0.051
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.950 0.050
S06.3 Focal brain injury
0.000 0.950 0.050
N93.8 Other specified abnormal uterine and vaginal bleeding
0.000 0.951 0.049
S06.0 Concussion
0.000 0.951 0.049
R35 Polyuria
0.049 0.951 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.951 0.048
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.952 0.048
E66.1 Drug-induced obesity
0.000 0.952 0.048
S06.2 Diffuse brain injury
0.000 0.953 0.047
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.953 0.046
S06.5 Traumatic subdural haemorrhage
0.000 0.954 0.046
S02.60 Fracture of mandible (closed)
0.000 0.954 0.046
S06.00 Concussion (without open intracranial wound)
0.000 0.955 0.045
C69 Malignant neoplasm of eye and adnexa
0.045 0.955 0.000
S00 Superficial injury of head
0.000 0.955 0.045
S05 Injury of eye and orbit
0.000 0.955 0.045
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.956 0.044
M25.39 Other instability of joint (Site unspecified)
0.000 0.956 0.043
M25.38 Other instability of joint (Other)
0.000 0.956 0.043
M25.35 Other instability of joint (Pelvic region and thigh)
0.000 0.956 0.043
M25.32 Other instability of joint (Upper arm)
0.000 0.956 0.043
M25.30 Other instability of joint (Multiple sites)
0.000 0.956 0.043
M25.31 Other instability of joint (Shoulder region)
0.000 0.956 0.043
S00.1 Contusion of eyelid and periocular area
0.000 0.957 0.043
S09 Other and unspecified injuries of head
0.000 0.958 0.042
M25.37 Other instability of joint (Ankle and foot)
0.000 0.958 0.042
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.958 0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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