TreeWAS – Variant ID: rs9267873

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
M20-M25 Other joint disorders	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.000	0.001	0.999
M35 Other systemic involvement of connective tissue	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
E10.3 With ophthalmic complications	0.000	0.003	0.997
M31 Other necrotising vasculopathies	0.995	0.005	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.995	0.005	0.000
M06.3 Rheumatoid nodule	0.995	0.005	0.000
M20 Acquired deformities of fingers and toes	0.994	0.006	0.000
M20.1 Hallux valgus (acquired)	0.991	0.009	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.010	0.990
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.990	0.010	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.011	0.989
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.012	0.988
M45-M49 Spondylopathies	0.987	0.013	0.000
N18 Chronic renal failure	0.000	0.014	0.986
M45 Ankylosing spondylitis	0.985	0.015	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.016	0.984
M45.X9 Ankylosing spondylitis (Site unspecified)	0.983	0.017	0.000
E10.9 Without complications	0.000	0.021	0.979
M31.6 Other giant cell arteritis	0.979	0.021	0.000
K51 Ulcerative colitis	0.978	0.022	0.000
E10.1 With ketoacidosis	0.000	0.026	0.974
M06.34 Rheumatoid nodule (Hand)	0.971	0.029	0.000
M20.3 Other deformity of hallux (acquired)	0.968	0.032	0.000
E14 Unspecified diabetes mellitus	0.000	0.034	0.966
L40.5 Arthropathic psoriasis	0.000	0.035	0.965
L40 Psoriasis	0.000	0.037	0.963
N18.4 Chronic kidney disease, stage 4	0.000	0.039	0.961
L40.9 Psoriasis, unspecified	0.000	0.041	0.959
M06.0 Seronegative rheumatoid arthritis	0.953	0.047	0.000
K51.8 Other ulcerative colitis	0.944	0.056	0.000
M34 Systemic sclerosis	0.943	0.057	0.000
E00-E07 Disorders of thyroid gland	0.000	0.057	0.943
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.059	0.941
E11 Non-insulin-dependent diabetes mellitus	0.000	0.062	0.938
E13 Other specified diabetes mellitus	0.000	0.064	0.936
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.931	0.069	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.071	0.929
K51.3 Ulcerative (chronic) rectosigmoiditis	0.926	0.074	0.000
E10.4 With neurological complications	0.000	0.080	0.920
N00-N08 Glomerular diseases	0.000	0.095	0.905
N04 Nephrotic syndrome	0.000	0.097	0.903
N04.9 Unspecified	0.000	0.099	0.901
N05 Unspecified nephritic syndrome	0.000	0.099	0.901
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.900	0.100	0.000
J47 Bronchiectasis	0.899	0.101	0.000
M31.3 Wegener's granulomatosis	0.894	0.106	0.000
E13.9 Without complications	0.000	0.108	0.892
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.892	0.108	0.000
E11.1 With ketoacidosis	0.000	0.108	0.892
N18.0 End-stage renal disease	0.000	0.118	0.882
M06.4 Inflammatory polyarthropathy	0.879	0.121	0.000
M12 Other specific arthropathies	0.874	0.126	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.126	0.874
N18.3 Chronic kidney disease, stage 3	0.000	0.131	0.869
N17-N19 Renal failure	0.000	0.132	0.868
N05.9 Unspecified	0.000	0.133	0.867
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.864	0.136	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.856	0.144	0.000
M00-M03 Infectious arthropathies	0.854	0.146	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.150	0.850
E14.8 With unspecified complications	0.000	0.154	0.846
N18.5 Chronic kidney disease, stage 5	0.000	0.157	0.843
E14.3 With ophthalmic complications	0.000	0.163	0.837
E11.6 With other specified complications	0.000	0.163	0.837
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.835	0.165	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.831	0.169	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.830	0.170	0.000
E14.9 Without complications	0.000	0.173	0.827
M35.8 Other specified systemic involvement of connective tissue	0.827	0.173	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.174	0.826
M34.9 Systemic sclerosis, unspecified	0.820	0.180	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.818	0.182	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.818	0.182	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.183	0.817
K51.5 Mucosal proctocolitis	0.816	0.184	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.814	0.186	0.000
E10.8 With unspecified complications	0.000	0.195	0.805
E11.5 With peripheral circulatory complications	0.000	0.195	0.805
L40.1 Generalised pustular psoriasis	0.000	0.196	0.804
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.803	0.197	0.000
M35.1 Other overlap syndromes	0.802	0.198	0.000
M34.8 Other forms of systemic sclerosis	0.801	0.199	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.801	0.199	0.000
L40.0 Psoriasis vulgaris	0.000	0.200	0.800
E11.2 With renal complications	0.000	0.202	0.798
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.795	0.205	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.794	0.206	0.000
M05.8 Other seropositive rheumatoid arthritis	0.794	0.206	0.000
E14.1 With ketoacidosis	0.000	0.206	0.794
K90 Intestinal malabsorption	0.000	0.207	0.793
K51.2 Ulcerative (chronic) proctitis	0.790	0.210	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.790	0.210	0.000
M05.2 Rheumatoid vasculitis	0.790	0.210	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.787	0.212	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.216	0.784
M06.30 Rheumatoid nodule (Multiple sites)	0.784	0.216	0.000
N05.1 Focal and segmental glomerular lesions	0.000	0.217	0.783
M05.1 Rheumatoid lung disease	0.781	0.219	0.000
N17 Acute renal failure	0.000	0.219	0.781
E10.2 With renal complications	0.000	0.221	0.779
M91-M94 Chondropathies	0.778	0.222	0.000
M34.1 CR(E)ST syndrome	0.777	0.223	0.000
M20.0 Deformity of finger(s)	0.774	0.226	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.227	0.773
M30 Polyarteritis nodosa and related conditions	0.772	0.228	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.768	0.232	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.765	0.235	0.000
M31.0 Hypersensitivity angiitis	0.761	0.239	0.000
M95.0 Acquired deformity of nose	0.760	0.240	0.000
E11.9 Without complications	0.000	0.243	0.757
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.756	0.243	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.752	0.248	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.751	0.249	0.000
M31.8 Other specified necrotising vasculopathies	0.749	0.251	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.746	0.254	0.000
E14.4 With neurological complications	0.000	0.255	0.745
N04.1 Focal and segmental glomerular lesions	0.000	0.255	0.745
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.743	0.257	0.000
M06.8 Other specified rheumatoid arthritis	0.741	0.259	0.000
N17.9 Acute renal failure, unspecified	0.000	0.263	0.737
K90.9 Intestinal malabsorption, unspecified	0.000	0.263	0.737
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.263	0.737
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.265	0.735
M08 Juvenile arthritis	0.734	0.266	0.000
M06.33 Rheumatoid nodule (Forearm)	0.734	0.266	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.271	0.729
M02 Reactive arthropathies	0.729	0.271	0.000
M12.2 Villonodular synovitis (pigmented)	0.729	0.271	0.000
M48 Other spondylopathies	0.728	0.272	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.274	0.726
E14.2 Withrenal complications	0.000	0.278	0.722
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.720	0.280	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.282	0.718
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.284	0.716
M31.2 Lethal midline granuloma	0.713	0.286	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.713	0.287	0.000
M06.38 Rheumatoid nodule (Other)	0.713	0.287	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.713	0.287	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.713	0.287	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.712	0.288	0.000
L40.4 Guttate psoriasis	0.000	0.288	0.712
M06.04 Seronegative rheumatoid arthritis (Hand)	0.710	0.290	0.000
E05.5 Thyroid crisis or storm	0.000	0.291	0.709
E05.4 Thyrotoxicosis factitia	0.000	0.291	0.709
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.291	0.709
M12.3 Palindromic rheumatism	0.708	0.292	0.000
E40-E46 Malnutrition	0.000	0.293	0.707
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.707	0.293	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.706	0.293	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.706	0.293	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.706	0.293	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.706	0.293	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.706	0.293	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.706	0.293	0.000
M49 Spondylopathies in diseases classified elsewhere	0.705	0.294	0.000
E14.7 With multiple complications	0.000	0.307	0.693
M31.7 Microscopic polyangiitis	0.693	0.307	0.000
L40.8 Other psoriasis	0.000	0.309	0.691
L40.2 Acrodermatitis continua	0.000	0.309	0.691
M45.X2 Ankylosing spondylitis (Cervical region)	0.688	0.312	0.000
E10.5 With peripheral circulatory complications	0.000	0.312	0.688
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.686	0.313	0.000
E10.0 With coma	0.000	0.315	0.685
N18.8 Other chronic renal failure	0.000	0.316	0.684
M06.08 Seronegative rheumatoid arthritis (Other)	0.683	0.317	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.683	0.317	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.683	0.317	0.000
K90.8 Other intestinal malabsorption	0.000	0.319	0.681
M31.1 Thrombotic microangiopathy	0.679	0.321	0.000
E14.5 With peripheral circulatory complications	0.000	0.322	0.678
M06.98 Rheumatoid arthritis, unspecified (Other)	0.677	0.322	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.677	0.323	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.676	0.324	0.000
M34.0 Progressive systemic sclerosis	0.676	0.324	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.324	0.676
E00 Congenital iodine-deficiency syndrome	0.000	0.324	0.676
N13 Obstructive and reflux uropathy	0.000	0.326	0.674
E11.7 With multiple complications	0.000	0.327	0.673
E13.8 With unspecified complications	0.000	0.329	0.671
E13.7 With multiple complications	0.000	0.329	0.671
E13.6 With other specified complications	0.000	0.329	0.671
E13.5 With peripheral circulatory complications	0.000	0.329	0.671
E13.4 With neurological complications	0.000	0.329	0.671
E13.2 With renal complications	0.000	0.329	0.671
E13.1 With ketoacidosis	0.000	0.329	0.671
E13.0 With coma	0.000	0.329	0.671
M10 Gout	0.670	0.330	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.670	0.330	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.331	0.669
N11 Chronic tubulo-interstitial nephritis	0.000	0.334	0.666
E13.3 With ophthalmic complications	0.000	0.336	0.664
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.664	0.336	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.662	0.338	0.000
E10.7 With multiple complications	0.000	0.345	0.655
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.346	0.654
M00 Pyogenic arthritis	0.654	0.346	0.000
K51.4 Pseudopolyposis of colon	0.651	0.349	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.650	0.350	0.000
N25-N29 Other disorders of kidney and ureter	0.000	0.350	0.650
E14.6 With other specified complications	0.000	0.351	0.648
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.351	0.648
N06 Isolated proteinuria with specified morphological lesion	0.000	0.351	0.648
N01 Rapidly progressive nephritic syndrome	0.000	0.351	0.648
N00 Acute nephritic syndrome	0.000	0.351	0.648
M35.2 Behcet's disease	0.648	0.352	0.000
E16.1 Other hypoglycaemia	0.000	0.352	0.648
N04.8 Other	0.000	0.352	0.648
N04.7 Diffuse crescentic glomerulonephritis	0.000	0.352	0.648
N04.6 Dense deposit disease	0.000	0.352	0.648
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.352	0.648
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.352	0.648
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.352	0.648
N04.2 Diffuse membranous glomerulonephritis	0.000	0.352	0.648
N08.5 Glomerular disorders in systemic connective tissue disorders	0.000	0.353	0.647
N05.6 Dense deposit disease	0.000	0.354	0.646
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.354	0.646
N05.0 Minor glomerular abnormality	0.000	0.354	0.646
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.646	0.354	0.000
M12.5 Traumatic arthropathy	0.644	0.356	0.000
E03 Other hypothyroidism	0.000	0.358	0.641
N04.0 Minor glomerular abnormality	0.000	0.361	0.639
M14 Arthropathies in other diseases classified elsewhere	0.636	0.363	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.365	0.635
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.366	0.633
N03 Chronic nephritic syndrome	0.000	0.367	0.633
M06.48 Inflammatory polyarthropathy (Other)	0.630	0.370	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.630	0.370	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.630	0.370	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.630	0.370	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.630	0.370	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.630	0.370	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.630	0.370	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.630	0.370	0.000
M12.4 Intermittent hydrarthrosis	0.627	0.373	0.000
M12.1 Kaschin-Beck disease	0.627	0.373	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.627	0.373	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.373	0.627
M05.19 Rheumatoid lung disease (Site unspecified)	0.624	0.375	0.000
M31.9 Necrotising vasculopathy, unspecified	0.623	0.377	0.000
N13.4 Hydroureter	0.000	0.382	0.618
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.612	0.388	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.612	0.388	0.000
M99 Biomechanical lesions, not elsewhere classified	0.612	0.388	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.612	0.388	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.607	0.393	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.395	0.605
M32 Systemic lupus erythematosus	0.605	0.395	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.605	0.395	0.000
E06 Thyroiditis	0.000	0.396	0.603
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.603	0.397	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.600	0.400	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.400	0.600
M60-M63 Disorders of muscles	0.599	0.401	0.000
M10.0 Idiopathic gout	0.598	0.402	0.000
M95.2 Other acquired deformity of head	0.597	0.403	0.000
M02.9 Reactive arthopathy, unspecified	0.597	0.403	0.000
E11.0 With coma	0.000	0.405	0.595
M11 Other crystal arthropathies	0.594	0.406	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.593	0.407	0.000
M40-M43 Deforming dorsopathies	0.593	0.407	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.407	0.592
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.407	0.592
E16.4 Abnormal secretion of gastrin	0.000	0.407	0.592
E16.3 Increased secretion of glucagon	0.000	0.407	0.592
M02.3 Reiter's disease	0.589	0.411	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.000	0.414	0.586
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.000	0.414	0.586
N08.1 Glomerular disorders in neoplastic diseases	0.000	0.414	0.586
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.000	0.414	0.586
M95.3 Acquired deformity of neck	0.584	0.416	0.000
E10.6 With other specified complications	0.000	0.419	0.581
L40-L45 Papulosquamous disorders	0.000	0.420	0.580
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.000	0.422	0.578
M92 Other juvenile osteochondrosis	0.576	0.423	0.000
M93 Other osteochondropathies	0.574	0.426	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.573	0.427	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.572	0.428	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.569	0.430	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.569	0.430	0.000
M95.5 Acquired deformity of pelvis	0.569	0.430	0.000
M95.1 Cauliflower ear	0.569	0.430	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.569	0.431	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.569	0.431	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.569	0.431	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.569	0.431	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.569	0.431	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.569	0.431	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.569	0.431	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.569	0.431	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.569	0.431	0.000
N26 Unspecified contracted kidney	0.000	0.431	0.569
K90.3 Pancreatic steatorrhoea	0.000	0.431	0.569
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.431	0.569
K90.1 Tropical sprue	0.000	0.431	0.569
E14.0 With coma	0.000	0.433	0.567
M05.28 Rheumatoid vasculitis (Other)	0.566	0.434	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.566	0.434	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.566	0.434	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.566	0.434	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.566	0.434	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.566	0.434	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.566	0.434	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.566	0.434	0.000
M05.18 Rheumatoid lung disease (Other)	0.560	0.440	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.560	0.440	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.560	0.440	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.560	0.440	0.000
M05.14 Rheumatoid lung disease (Hand)	0.560	0.440	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.560	0.440	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.560	0.440	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.560	0.440	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.560	0.440	0.000
N17.2 Acute renal failure with medullary necrosis	0.000	0.440	0.560
M20.4 Other hammer toe(s) (acquired)	0.559	0.441	0.000
N17.8 Other acute renal failure	0.000	0.441	0.558
M12.30 Palindromic rheumatism (Multiple sites)	0.556	0.444	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.444	0.556
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.555	0.445	0.000
E03.8 Other specified hypothyroidism	0.000	0.446	0.554
M30.8 Other conditions related to polyarteritis nodosa	0.554	0.446	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.554	0.446	0.000
M30.2 Juvenile polyarteritis	0.554	0.446	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.552	0.448	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.551	0.449	0.000
M94 Other disorders of cartilage	0.549	0.451	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.548	0.452	0.000
M46 Other inflammatory spondylopathies	0.547	0.453	0.000
M08.0 Juvenile rheumatoid arthritis	0.544	0.456	0.000
E07 Other disorders of thyroid	0.000	0.460	0.540
E46 Unspecified protein-energy malnutrition	0.000	0.460	0.540
M65-M68 Disorders of synovium and tendon	0.539	0.461	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.538	0.462	0.000
M36.3 Arthropathy in other blood disorders	0.538	0.462	0.000
M36.2 Haemophilic arthropathy	0.538	0.462	0.000
M36.1 Arthropathy in neoplastic disease	0.538	0.462	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.538	0.462	0.000
N02 Recurrent and persistent haematuria	0.000	0.462	0.538
N25 Disorders resulting from impaired renal tubular function	0.000	0.464	0.536
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.466	0.534
M48.8 Other specified spondylopathies	0.534	0.466	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.531	0.469	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.531	0.469	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.531	0.469	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.531	0.469	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.531	0.469	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.531	0.469	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.531	0.469	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.531	0.469	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.531	0.469	0.000
N05.8 Other	0.000	0.472	0.528
M08.9 Juvenile arthritis, unspecified	0.526	0.473	0.000
M08.8 Other juvenile arthritis	0.526	0.473	0.000
M08.4 Pauciarticular juvenile arthritis	0.526	0.473	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.526	0.473	0.000
M08.2 Juvenile arthritis with systemic onset	0.526	0.473	0.000
M08.1 Juvenile ankylosing spondylitis	0.526	0.473	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.477	0.523
M02.8 Other reactive arthropathies	0.523	0.477	0.000
M02.2 Postimmunisation arthropathy	0.523	0.477	0.000
M02.1 Postdysenteric arthropathy	0.523	0.477	0.000
M02.0 Arthropathy following intestinal bypass	0.523	0.477	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.522	0.477	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.522	0.477	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.522	0.477	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.522	0.477	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.522	0.477	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.522	0.477	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.522	0.477	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.522	0.477	0.000
M48.4 Fatigue fracture of vertebra	0.522	0.478	0.000
M48.3 Traumatic spondylopathy	0.522	0.478	0.000
M48.2 Kissing spine	0.522	0.478	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.522	0.478	0.000
L43 Lichen planus	0.000	0.480	0.520
M48.9 Spondylopathy, unspecified	0.518	0.482	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.514	0.486	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.487	0.513
G37 Other demyelinating diseases of central nervous system	0.513	0.487	0.000
M12.38 Palindromic rheumatism (Other)	0.508	0.492	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.508	0.492	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.508	0.492	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.508	0.492	0.000
M12.34 Palindromic rheumatism (Hand)	0.508	0.492	0.000
M12.33 Palindromic rheumatism (Forearm)	0.508	0.492	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.508	0.492	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.508	0.492	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.493	0.507
E45 Retarded development following protein-energy malnutrition	0.000	0.493	0.507
E43 Unspecified severe protein-energy malnutrition	0.000	0.493	0.507
E42 Marasmic kwashiorkor	0.000	0.493	0.507
E41 Nutritional marasmus	0.000	0.493	0.507
E40 Kwashiorkor	0.000	0.493	0.507
K51.0 Ulcerative (chronic) enterocolitis	0.506	0.494	0.000
N13.6 Pyonephrosis	0.000	0.494	0.506
M49.8 Spondylopathy in other diseases classified elsewhere	0.506	0.494	0.000
M49.4 Neuropathic spondylopathy	0.506	0.494	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.506	0.494	0.000
M49.2 Enterobacterial spondylitis	0.506	0.494	0.000
M49.1 Brucella spondylitis	0.506	0.494	0.000
M49.0 Tuberculosis of spine	0.506	0.494	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.504	0.496	0.000
M10.09 Idiopathic gout (Site unspecified)	0.504	0.496	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.498	0.501
L43.9 Lichen planus, unspecified	0.000	0.502	0.498
M14.8 Arthropathies in other specified diseases classified elsewhere	0.496	0.504	0.000
M00.9 Pyogenic arthritis, unspecified	0.494	0.506	0.000
N02.2 Diffuse membranous glomerulonephritis	0.000	0.509	0.491
M02.39 Reiter's disease (Site unspecified)	0.489	0.511	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.511	0.489
M92.7 Juvenile osteochondrosis of metatarsus	0.489	0.511	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.487	0.513	0.000
N15 Other renal tubulo-interstitial diseases	0.000	0.513	0.487
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.514	0.486
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.515	0.484
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.515	0.484
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.515	0.484
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.515	0.484
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.515	0.484

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations