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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267955
log Bayes Factor = 194.743
Chromosome 6   position 32,213,150  (GRCh37) Explore rs9267955 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.001 0.999
E14.9 Without complications
0.000 0.002 0.998
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
G37.9 Demyelinating disease of central nervous system, unspecified
0.997 0.003 0.000
E14.3 With ophthalmic complications
0.000 0.003 0.997
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.004 0.996
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.004 0.996
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.007 0.993
H43-H45 Disorders of vitreous body and globe
0.000 0.008 0.992
J33.9 Nasal polyp, unspecified
0.000 0.008 0.992
J33 Nasal polyp
0.000 0.008 0.992
I25 Chronic ischaemic heart disease
0.000 0.009 0.991
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.009 0.991
H43 Disorders of vitreous body
0.000 0.010 0.990
I20 Angina pectoris
0.000 0.011 0.989
L40-L45 Papulosquamous disorders
0.000 0.011 0.989
E05.9 Thyrotoxicosis, unspecified
0.000 0.012 0.988
L40 Psoriasis
0.000 0.014 0.986
L43 Lichen planus
0.000 0.014 0.986
J45.9 Asthma, unspecified
0.000 0.016 0.984
I22 Subsequent myocardial infarction
0.000 0.016 0.984
L43.9 Lichen planus, unspecified
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.018 0.982
L40.5 Arthropathic psoriasis
0.000 0.020 0.980
K90 Intestinal malabsorption
0.000 0.020 0.980
E11.3 With ophthalmic complications
0.000 0.021 0.979
Chapter XI Diseases of the digestive system
0.000 0.023 0.977
K90-K93 Other diseases of the digestive system
0.000 0.024 0.976
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.024 0.976
H40-H42 Glaucoma
0.000 0.025 0.975
K51.8 Other ulcerative colitis
0.972 0.028 0.000
I20.9 Angina pectoris, unspecified
0.000 0.031 0.969
J33.8 Other polyp of sinus
0.000 0.031 0.969
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.034 0.966
J33.0 Polyp of nasal cavity
0.000 0.035 0.965
K70-K77 Diseases of liver
0.000 0.035 0.965
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.036 0.964
H43.3 Other vitreous opacities
0.000 0.037 0.963
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.039 0.961
J45 Asthma
0.000 0.040 0.960
H40 Glaucoma
0.000 0.042 0.958
H40.9 Glaucoma, unspecified
0.000 0.044 0.956
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.046 0.954
Chapter X Diseases of the respiratory system
0.000 0.046 0.954
J40-J47 Chronic lower respiratory diseases
0.000 0.047 0.953
H43.8 Other disorders of vitreous body
0.000 0.048 0.952
E11.1 With ketoacidosis
0.000 0.051 0.949
K74 Fibrosis and cirrhosis of liver
0.000 0.059 0.941
E07 Other disorders of thyroid
0.000 0.059 0.941
H34 Retinal vascular occlusions
0.000 0.061 0.939
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.063 0.937
J30-J39 Other diseases of upper respiratory tract
0.000 0.069 0.931
E10.2 With renal complications
0.000 0.071 0.929
I25.5 Ischaemic cardiomyopathy
0.000 0.072 0.928
I25.1 Atherosclerotic heart disease
0.000 0.073 0.927
K74.3 Primary biliary cirrhosis
0.000 0.077 0.923
I25.2 Old myocardial infarction
0.000 0.084 0.916
E11.5 With peripheral circulatory complications
0.000 0.087 0.913
I12 Hypertensive renal disease
0.000 0.088 0.912
M07 Psoriatic and enteropathic arthropathies
0.000 0.094 0.906
E07.9 Disorder of thyroid, unspecified
0.000 0.094 0.906
E11.2 With renal complications
0.000 0.097 0.903
E06 Thyroiditis
0.000 0.107 0.893
K51.2 Ulcerative (chronic) proctitis
0.891 0.109 0.000
I15 Secondary hypertension
0.000 0.111 0.889
I20.1 Angina pectoris with documented spasm
0.000 0.112 0.888
I20.0 Unstable angina
0.000 0.113 0.887
I24 Other acute ischaemic heart diseases
0.000 0.116 0.884
E03.8 Other specified hypothyroidism
0.000 0.116 0.884
K72 Hepatic failure, not elsewhere classified
0.000 0.119 0.881
L40.9 Psoriasis, unspecified
0.000 0.123 0.877
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.128 0.872
G37.8 Other specified demyelinating diseases of central nervous system
0.871 0.129 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.136 0.864
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.139 0.861
J46 Status asthmaticus
0.000 0.139 0.861
E13 Other specified diabetes mellitus
0.000 0.141 0.859
K50-K52 Noninfective enteritis and colitis
0.031 0.144 0.825
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.147 0.853
K51.4 Pseudopolyposis of colon
0.851 0.149 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.154 0.846
M06.4 Inflammatory polyarthropathy
0.000 0.157 0.843
H25-H28 Disorders of lens
0.000 0.157 0.843
M07.3 Other psoriatic arthropathies
0.000 0.161 0.839
M70-M79 Other soft tissue disorders
0.000 0.162 0.838
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.168 0.832
H34.2 Other retinal artery occlusions
0.000 0.169 0.831
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.830 0.170 0.000
E06.3 Autoimmune thyroiditis
0.000 0.173 0.827
K51.5 Mucosal proctocolitis
0.826 0.174 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.175 0.825
E78.5 Hyperlipidaemia, unspecified
0.000 0.175 0.825
E83 Disorders of mineral metabolism
0.774 0.176 0.050
J43 Emphysema
0.000 0.177 0.823
E78.1 Pure hyperglyceridaemia
0.000 0.177 0.823
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.177 0.823
M06.0 Seronegative rheumatoid arthritis
0.000 0.182 0.818
H35 Other retinal disorders
0.000 0.186 0.814
M06.3 Rheumatoid nodule
0.000 0.188 0.812
H34.8 Other retinal vascular occlusions
0.000 0.193 0.807
K72.9 Hepatic failure, unspecified
0.000 0.197 0.803
K75 Other inflammatory liver diseases
0.000 0.200 0.800
I11 Hypertensive heart disease
0.000 0.207 0.793
E11.6 With other specified complications
0.000 0.207 0.793
H43.1 Vitreous haemorrhage
0.000 0.209 0.791
E16.1 Other hypoglycaemia
0.000 0.214 0.786
H40.5 Glaucoma secondary to other eye disorders
0.000 0.216 0.784
E11.8 With unspecified complications
0.000 0.217 0.782
I15.1 Hypertension secondary to other renal disorders
0.000 0.218 0.781
E74 Other disorders of carbohydrate metabolism
0.000 0.220 0.780
Chapter VIII Diseases of the ear and mastoid process
0.000 0.222 0.778
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.224 0.776
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.224 0.776
E40-E46 Malnutrition
0.000 0.227 0.773
K74.5 Biliary cirrhosis, unspecified
0.000 0.228 0.772
J86 Pyothorax
0.000 0.228 0.772
E78.2 Mixed hyperlipidaemia
0.000 0.229 0.771
K74.6 Other and unspecified cirrhosis of liver
0.000 0.233 0.767
M77 Other enthesopathies
0.000 0.235 0.765
H43.9 Disorder of vitreous body, unspecified
0.000 0.238 0.762
K73 Chronic hepatitis, not elsewhere classified
0.000 0.238 0.762
H27 Other disorders of lens
0.000 0.240 0.759
M75 Shoulder lesions
0.000 0.242 0.758
E13.9 Without complications
0.000 0.243 0.757
H60-H62 Diseases of external ear
0.000 0.244 0.756
L40.8 Other psoriasis
0.000 0.246 0.754
M77.1 Lateral epicondylitis
0.000 0.250 0.750
E88 Other metabolic disorders
0.000 0.250 0.749
I23 Certain current complications following acute myocardial infarction
0.000 0.252 0.748
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.253 0.747
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.253 0.747
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.254 0.746
E11.4 With neurological complications
0.000 0.257 0.743
H25 Senile cataract
0.000 0.257 0.743
H61 Other disorders of external ear
0.000 0.258 0.742
L43.8 Other lichen planus
0.000 0.259 0.741
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.261 0.739
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.261 0.739
L40.0 Psoriasis vulgaris
0.000 0.262 0.738
M11 Other crystal arthropathies
0.000 0.263 0.737
K50 Crohn's disease [regional enteritis]
0.001 0.265 0.733
H25.1 Senile nuclear cataract
0.000 0.265 0.735
H40.1 Primary open-angle glaucoma
0.000 0.266 0.734
K75.4 Autoimmune hepatitis
0.000 0.266 0.734
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.266 0.734
M65-M68 Disorders of synovium and tendon
0.000 0.267 0.733
H34.1 Central retinal artery occlusion
0.000 0.267 0.733
J37 Chronic laryngitis and laryngotracheitis
0.000 0.269 0.731
J95-J99 Other diseases of the respiratory system
0.000 0.269 0.731
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.271 0.729
K51.1 Ulcerative (chronic) ileocolitis
0.729 0.271 0.000
M75.0 Adhesive capsulitis of shoulder
0.000 0.273 0.727
E83.3 Disorders of phosphorus metabolism
0.710 0.277 0.014
H43.2 Crystalline deposits in vitreous body
0.000 0.277 0.723
H61.0 Perichondritis of external ear
0.000 0.281 0.719
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.4 With neurological complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H30 Chorioretinal inflammation
0.000 0.284 0.716
G36 Other acute disseminated demyelination
0.716 0.284 0.000
G37.5 Concentric sclerosis [Balo]
0.715 0.284 0.000
G37.4 Subacute necrotising myelitis
0.715 0.284 0.000
G37.2 Central pontine myelinolysis
0.715 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.284 0.000
G37.0 Diffuse sclerosis
0.715 0.284 0.000
E78.6 Lipoprotein deficiency
0.000 0.286 0.714
E78.3 Hyperchylomicronaemia
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.288 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.288 0.712
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.288 0.711
J33.1 Polypoid sinus degeneration
0.000 0.289 0.711
I25.6 Silent myocardial ischaemia
0.000 0.289 0.710
H43.0 Vitreous prolapse
0.000 0.290 0.710
H40.4 Glaucoma secondary to eye inflammation
0.000 0.290 0.710
K51.0 Ulcerative (chronic) enterocolitis
0.709 0.291 0.000
L44 Other papulosquamous disorders
0.000 0.291 0.709
L41 Parapsoriasis
0.000 0.291 0.709
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.291 0.709
L40.4 Guttate psoriasis
0.000 0.293 0.707
L40.3 Pustulosis palmaris et plantaris
0.000 0.293 0.707
L40.2 Acrodermatitis continua
0.000 0.293 0.707
L40.1 Generalised pustular psoriasis
0.000 0.293 0.707
L43.3 Subacute (active) lichen planus
0.000 0.293 0.707
L43.2 Lichenoid drug reaction
0.000 0.293 0.707
L43.1 Bullous lichen planus
0.000 0.293 0.707
L43.0 Hypertrophic lichen planus
0.000 0.293 0.707
K90.3 Pancreatic steatorrhoea
0.000 0.297 0.702
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.297 0.702
K90.1 Tropical sprue
0.000 0.297 0.702
I15.9 Seconday hypertension, unspecified
0.000 0.297 0.703
I25.4 Coronary artery aneurysm
0.000 0.299 0.701
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.299 0.701
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.300 0.700
H42 Glaucoma in diseases classified elsewhere
0.000 0.301 0.699
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.304 0.696
M12 Other specific arthropathies
0.000 0.306 0.694
K77 Liver disorders in diseases classified elsewhere
0.000 0.308 0.691
K71 Toxic liver disease
0.000 0.308 0.691
K72.0 Acute and subacute hepatic failure
0.000 0.312 0.688
J45.8 Mixed asthma
0.000 0.312 0.688
J45.1 Nonallergic asthma
0.000 0.312 0.688
M14 Arthropathies in other diseases classified elsewhere
0.000 0.312 0.688
H40.6 Glaucoma secondary to drugs
0.000 0.313 0.687
H40.3 Glaucoma secondary to eye trauma
0.000 0.313 0.687
H35.4 Peripheral retinal degeneration
0.000 0.314 0.686
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.314 0.686
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.315 0.685
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.316 0.684
E11.0 With coma
0.000 0.316 0.684
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.318 0.682
H35.2 Other proliferative retinopathy
0.000 0.320 0.680
J43.9 Emphysema, unspecified
0.000 0.321 0.679
K74.4 Secondary biliary cirrhosis
0.000 0.325 0.675
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.325 0.675
E07.1 Dyshormogenetic goitre
0.000 0.325 0.674
E07.0 Hypersecretion of calcitonin
0.000 0.325 0.674
J43.2 Centrilobular emphysema
0.000 0.327 0.673
M45-M49 Spondylopathies
0.000 0.327 0.673
H34.0 Transient retinal artery occlusion
0.000 0.327 0.673
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.327 0.673
H35.8 Other specified retinal disorders
0.000 0.327 0.673
H35.5 Hereditary retinal dystrophy
0.000 0.332 0.668
K90.9 Intestinal malabsorption, unspecified
0.000 0.333 0.667
E83.9 Disorder of mineral metabolism, unspecified
0.637 0.334 0.029
I12.0 Hypertensive renal disease with renal failure
0.000 0.334 0.666
M06.34 Rheumatoid nodule (Hand)
0.000 0.336 0.664
J41 Simple and mucopurulent chronic bronchitis
0.000 0.336 0.663
E84 Cystic fibrosis
0.000 0.337 0.663
J86.9 Pyothorax without fistula
0.000 0.340 0.660
I25.3 Aneurysm of heart
0.000 0.340 0.660
E79 Disorders of purine and pyrimidine metabolism
0.000 0.341 0.659
H34.9 Retinal vascular occlusion, unspecified
0.000 0.342 0.658
K50.8 Other Crohn's disease
0.000 0.342 0.657
J86.0 Pyothorax with fistula
0.000 0.343 0.657
E05.8 Other thyrotoxicosis
0.000 0.343 0.656
M75.2 Bicipital tendinitis
0.000 0.344 0.656
H27.8 Other specified disorders of lens
0.000 0.347 0.653
L42 Pityriasis rosea
0.000 0.348 0.652
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.349 0.651
M45 Ankylosing spondylitis
0.000 0.350 0.650
M07.6 Other enteropathic arthropathies
0.000 0.350 0.650
M07.5 Arthropathy in ulcerative colitis
0.000 0.350 0.650
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.350 0.650
M07.2 Psoriatic spondylitis
0.000 0.350 0.650
M07.1 Arthritis mutilans
0.000 0.350 0.650
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.350 0.650
K55-K64 Other diseases of intestines
0.000 0.353 0.647
J85 Abscess of lung and mediastinum
0.000 0.359 0.641
E06.5 Other chronic thyroiditis
0.000 0.359 0.640
E06.4 Drug-induced thyroiditis
0.000 0.359 0.640
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.359 0.640
E06.1 Subacute thyroiditis
0.000 0.359 0.640
E06.0 Acute thyroiditis
0.000 0.359 0.640
E78.8 Other disorders of lipoprotein metabolism
0.000 0.359 0.640
M76 Enthesopathies of lower limb, excluding foot
0.000 0.360 0.640
I15.8 Other secondary hypertension
0.000 0.363 0.637
I15.2 Hypertension secondary to endocrine disorders
0.000 0.363 0.637
I15.0 Renovascular hypertension
0.000 0.363 0.637
H35.6 Retinal haemorrhage
0.000 0.367 0.633
K72.1 Chronic hepatic failure
0.000 0.368 0.631
M65 Synovitis and tenosynovitis
0.000 0.369 0.631
I22.8 Subsequent myocardial infarction of other sites
0.000 0.369 0.631
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.369 0.631
H61.8 Other specified disorders of external ear
0.000 0.371 0.629
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.372 0.628
K60 Fissure and fistula of anal and rectal regions
0.000 0.376 0.624
K82 Other diseases of gallbladder
0.000 0.378 0.622
L10-L14 Bullous disorders
0.000 0.380 0.620
E07.8 Other specified disorders of thyroid
0.000 0.380 0.619
K50.1 Crohn's disease of large intestine
0.000 0.380 0.619
H61.3 Acquired stenosis of external ear canal
0.000 0.384 0.616
E13.8 With unspecified complications
0.000 0.384 0.616
E13.7 With multiple complications
0.000 0.384 0.616
E13.6 With other specified complications
0.000 0.384 0.616
E13.5 With peripheral circulatory complications
0.000 0.384 0.616
E13.4 With neurological complications
0.000 0.384 0.616
E13.3 With ophthalmic complications
0.000 0.384 0.616
E13.2 With renal complications
0.000 0.384 0.616
E13.1 With ketoacidosis
0.000 0.384 0.616
E13.0 With coma
0.000 0.384 0.616
M72 Fibroblastic disorders
0.000 0.384 0.615
J32 Chronic sinusitis
0.000 0.386 0.614
K82.8 Other specified diseases of gallbladder
0.000 0.388 0.612
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.390 0.610
E46 Unspecified protein-energy malnutrition
0.000 0.390 0.610
I21 Acute myocardial infarction
0.000 0.390 0.610
M75.3 Calcific tendinitis of shoulder
0.000 0.391 0.609
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.393 0.607
M75.4 Impingement syndrome of shoulder
0.000 0.394 0.606
H61.1 Non-infective disorders of pinna
0.000 0.395 0.605
K52 Other non-infective gastro-enteritis and colitis
0.004 0.395 0.601
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.395 0.604
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.395 0.604
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.395 0.604
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.395 0.604
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.395 0.604
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.395 0.604
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.395 0.604
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.395 0.604
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.396 0.604
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.396 0.604
H27.0 Aphakia
0.000 0.397 0.603
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.397 0.602
M07.38 Other psoriatic arthropathies (Other)
0.000 0.398 0.601
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.398 0.601
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.398 0.601
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.398 0.601
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.398 0.601
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.398 0.601
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.399 0.601
K90.8 Other intestinal malabsorption
0.000 0.399 0.601
E06.9 Thyroiditis, unspecified
0.000 0.399 0.601
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.400 0.600
K73.9 Chronic hepatitis, unspecified
0.000 0.400 0.600
H27.1 Dislocation of lens
0.000 0.404 0.595
H35.7 Separation of retinal layers
0.000 0.406 0.594
J44 Other chronic obstructive pulmonary disease
0.000 0.406 0.594
M91-M94 Chondropathies
0.000 0.406 0.594
K63 Other diseases of intestine
0.000 0.406 0.594
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.408 0.592
E78.4 Other hyperlipidaemia
0.000 0.409 0.591
E83.8 Other disorders of mineral metabolism
0.555 0.409 0.036
E83.2 Disorders of zinc metabolism
0.555 0.409 0.036
E83.0 Disorders of copper metabolism
0.555 0.409 0.036
J43.8 Other emphysema
0.000 0.410 0.590
J43.1 Panlobular emphysema
0.000 0.410 0.590
J43.0 MacLeod's syndrome
0.000 0.410 0.590
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.411 0.589
J37.0 Chronic laryngitis
0.000 0.412 0.588
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.413 0.587
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.413 0.587
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.413 0.587
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.413 0.587
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.413 0.587
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.413 0.587
H35.1 Retinopathy of prematurity
0.000 0.416 0.584
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.416 0.584
M60-M63 Disorders of muscles
0.000 0.418 0.582
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.418 0.582
M06.38 Rheumatoid nodule (Other)
0.000 0.418 0.582
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.418 0.582
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.418 0.582
M06.33 Rheumatoid nodule (Forearm)
0.000 0.418 0.582
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.418 0.582
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.418 0.582
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.418 0.582
K60.0 Acute anal fissure
0.000 0.418 0.582
K75.9 Inflammatory liver disease, unspecified
0.000 0.419 0.581
K55 Vascular disorders of intestine
0.000 0.421 0.579
M10 Gout
0.000 0.423 0.577
K76 Other diseases of liver
0.000 0.425 0.575
E88.2 Lipomatosis, not elsewhere classified
0.000 0.425 0.575
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.426 0.573
K75.2 Nonspecific reactive hepatitis
0.000 0.426 0.573
K75.1 Phlebitis of portal vein
0.000 0.426 0.573
E73 Lactose intolerance
0.000 0.428 0.572
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.428 0.572
K60.5 Anorectal fistula
0.000 0.428 0.572
I24.1 Dressler's syndrome
0.000 0.429 0.571
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.431 0.569
I23.8 Other current complications following acute myocardial infarction
0.000 0.432 0.568
H31 Other disorders of choroid
0.000 0.433 0.566
K63.9 Disease of intestine, unspecified
0.000 0.433 0.567
H25.9 Senile cataract, unspecified
0.000 0.434 0.566
K58 Irritable bowel syndrome
0.000 0.435 0.565
K63.3 Ulcer of intestine
0.000 0.435 0.565
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.438 0.561
E65-E68 Obesity and other hyperalimentation
0.000 0.439 0.561
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.440 0.559
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.440 0.559
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.440 0.559
E74.2 Disorders of galactose metabolism
0.000 0.440 0.559
E74.1 Disorders of fructose metabolism
0.000 0.440 0.559
E74.0 Glycogen storage disease
0.000 0.440 0.559
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.441 0.559
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.441 0.559
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.443 0.557
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.444 0.556
E85 Amyloidosis
0.000 0.444 0.556
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.444 0.556
K76.8 Other specified diseases of liver
0.000 0.444 0.556
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.446 0.554
E45 Retarded development following protein-energy malnutrition
0.000 0.446 0.554
E43 Unspecified severe protein-energy malnutrition
0.000 0.446 0.554
E42 Marasmic kwashiorkor
0.000 0.446 0.554
E41 Nutritional marasmus
0.000 0.446 0.554
E40 Kwashiorkor
0.000 0.446 0.554
H35.9 Retinal disorder, unspecified
0.000 0.446 0.554
E80.4 Gilbert's syndrome
0.000 0.448 0.552
K52.1 Toxic gastro-enteritis and colitis
0.001 0.450 0.549
K74.0 Hepatic fibrosis
0.000 0.451 0.549
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.451 0.549
M77.3 Calcaneal spur
0.000 0.451 0.549
M77.2 Periarthritis of wrist
0.000 0.451 0.549
I21.4 Acute subendocardial myocardial infarction
0.000 0.452 0.548
M11.2 Other chondrocalcinosis
0.000 0.452 0.548
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.452 0.548
K74.1 Hepatic sclerosis
0.000 0.453 0.547
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.453 0.547
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.453 0.547
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.453 0.547
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.454 0.546

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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