TreeWAS – Variant ID: rs9268402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.000	1.000
D86 Sarcoidosis	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.000	1.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	0.000	0.000	1.000
M06.3 Rheumatoid nodule	0.000	0.000	1.000
D86.0 Sarcoidosis of lung	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.999	0.001	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.999	0.001	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.001	0.999
D86.9 Sarcoidosis, unspecified	0.997	0.003	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.003	0.997
D50-D53 Nutritional anaemias	0.995	0.005	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.006	0.994
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.007	0.993
M06.0 Seronegative rheumatoid arthritis	0.000	0.008	0.992
D68 Other coagulation defects	0.987	0.013	0.000
D69 Purpura and other haemorrhagic conditions	0.981	0.019	0.000
M07 Psoriatic and enteropathic arthropathies	0.000	0.021	0.979
L40 Psoriasis	0.000	0.021	0.979
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.023	0.977
L40.5 Arthropathic psoriasis	0.000	0.029	0.971
D52 Folate deficiency anaemia	0.970	0.030	0.000
D51 Vitamin B12 deficiency anaemia	0.969	0.031	0.000
K90 Intestinal malabsorption	0.969	0.031	0.000
M07.3 Other psoriatic arthropathies	0.000	0.036	0.964
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.045	0.955
M06.4 Inflammatory polyarthropathy	0.000	0.046	0.954
D52.9 Folate deficiency anaemia, unspecified	0.951	0.049	0.000
D69.6 Thrombocytopenia, unspecified	0.945	0.055	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.057	0.943
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.066	0.934
D68.8 Other specified coagulation defects	0.930	0.070	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.072	0.928
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.073	0.927
K90.9 Intestinal malabsorption, unspecified	0.922	0.078	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.084	0.916
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.086	0.914
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.086	0.914
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.902	0.098	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.099	0.901
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.900	0.100	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.103	0.897
D69.3 Idiopathic thrombocytopenic purpura	0.889	0.111	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.886	0.114	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.885	0.115	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.117	0.883
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.881	0.119	0.000
D60-D64 Aplastic and other anaemias	0.875	0.125	0.000
C82.0 Small cleaved cell, follicular	0.000	0.129	0.871
D86.3 Sarcoidosis of skin	0.868	0.132	0.000
D68.5 Primary Thrombophilia	0.867	0.133	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.134	0.866
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.138	0.862
D61 Other aplastic anaemias	0.849	0.151	0.000
D68.2 Hereditary deficiency of other clotting factors	0.848	0.152	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.154	0.846
G35-G37 Demyelinating diseases of the central nervous system	0.845	0.155	0.000
K90.8 Other intestinal malabsorption	0.838	0.161	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.168	0.832
M14 Arthropathies in other diseases classified elsewhere	0.000	0.172	0.827
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.173	0.827
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.178	0.822
D61.9 Aplastic anaemia, unspecified	0.822	0.178	0.000
D86.8 Sarcoidosis of other and combined sites	0.821	0.179	0.000
L40.0 Psoriasis vulgaris	0.000	0.179	0.821
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.190	0.810
G37 Other demyelinating diseases of central nervous system	0.809	0.191	0.000
D86.1 Sarcoidosis of lymph nodes	0.806	0.194	0.000
D55-D59 Haemolytic anaemias	0.805	0.195	0.000
D69.8 Other specified haemorrhagic conditions	0.801	0.199	0.000
D68.1 Hereditary factor XI deficiency	0.795	0.205	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.206	0.794
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.790	0.210	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.215	0.785
D89.9 Disorder involving the immune mechanism, unspecified	0.784	0.216	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.220	0.780
M14.6 Neuropathic arthropathy	0.000	0.243	0.757
D69.4 Other primary thrombocytopenia	0.756	0.244	0.000
D61.0 Constitutional aplastic anaemia	0.755	0.245	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.754	0.246	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.247	0.753
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.250	0.750
D68.4 Acquired coagulation factor deficiency	0.750	0.250	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.251	0.749
D69.5 Secondary thrombocytopenia	0.749	0.251	0.000
D69.0 Allergic purpura	0.743	0.257	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.741	0.259	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.264	0.736
G37.9 Demyelinating disease of central nervous system, unspecified	0.734	0.266	0.000
M12 Other specific arthropathies	0.000	0.268	0.732
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.283	0.717
M05.1 Rheumatoid lung disease	0.000	0.283	0.717
M05.0 Felty's syndrome	0.000	0.283	0.717
D81 Combined immunodeficiencies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.283	0.717
M08 Juvenile arthritis	0.000	0.283	0.717
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.283	0.717
M06.38 Rheumatoid nodule (Other)	0.000	0.283	0.717
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.283	0.717
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.283	0.717
M06.33 Rheumatoid nodule (Forearm)	0.000	0.283	0.717
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.716	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.716	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.716	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.716	0.283	0.000
D68.6 Other Thrombophilia	0.714	0.286	0.000
L40.4 Guttate psoriasis	0.000	0.288	0.712
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.289	0.711
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.289	0.711
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.289	0.711
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.289	0.711
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.289	0.711
M07.5 Arthropathy in ulcerative colitis	0.000	0.298	0.702
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.298	0.702
M07.2 Psoriatic spondylitis	0.000	0.298	0.702
M07.1 Arthritis mutilans	0.000	0.298	0.702
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.298	0.702
L40.2 Acrodermatitis continua	0.000	0.298	0.702
G37.8 Other specified demyelinating diseases of central nervous system	0.701	0.299	0.000
D52.8 Other folate deficiency anaemias	0.695	0.305	0.000
D52.1 Drug-induced folate deficiency anaemia	0.695	0.305	0.000
D52.0 Dietary folate deficiency anaemia	0.695	0.305	0.000
D51.2 Transcobalamin II deficiency	0.695	0.305	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.695	0.305	0.000
K90.3 Pancreatic steatorrhoea	0.694	0.305	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.694	0.305	0.000
K90.1 Tropical sprue	0.694	0.305	0.000
D66 Hereditary factor VIII deficiency	0.694	0.306	0.000
D59 Acquired haemolytic anaemia	0.693	0.307	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.309	0.691
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.309	0.691
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.309	0.691
M07.6 Other enteropathic arthropathies	0.000	0.310	0.690
D68.0 Von Willebrand's disease	0.688	0.312	0.000
D50 Iron deficiency anaemia	0.685	0.315	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.315	0.685
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.316	0.684
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.316	0.684
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.316	0.684
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.316	0.684
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.316	0.684
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.316	0.684
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.316	0.684
L40.8 Other psoriasis	0.000	0.321	0.679
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.321	0.678
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.322	0.678
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.327	0.673
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.673	0.327	0.000
M06.1 Adult-onset Still's disease	0.000	0.329	0.670
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.330	0.670
D82 Immunodeficiency associated with other major defects	0.668	0.332	0.000
M05.2 Rheumatoid vasculitis	0.000	0.333	0.667
D69.1 Qualitative platelet defects	0.665	0.334	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.335	0.665
C82.5 Diffuse follicle centre lymphoma	0.000	0.335	0.665
D83 Common variable immunodeficiency	0.665	0.335	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.340	0.660
D53 Other nutritional anaemias	0.651	0.349	0.000
D67 Hereditary factor IX deficiency	0.649	0.351	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.647	0.353	0.000
D64 Other anaemias	0.646	0.354	0.000
D89.3 Immune reconstitution syndrome	0.635	0.365	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.369	0.631
C82.2 Large cell, follicular	0.000	0.374	0.626
M14.2 Diabetic arthropathy	0.000	0.375	0.625
L40.3 Pustulosis palmaris et plantaris	0.000	0.379	0.621
D89.1 Cryoglobulinaemia	0.621	0.379	0.000
D56 Thalassaemia	0.619	0.381	0.000
L40.1 Generalised pustular psoriasis	0.000	0.384	0.616
D61.8 Other specified aplastic anaemias	0.609	0.391	0.000
D61.3 Idiopathic aplastic anaemia	0.609	0.391	0.000
D61.2 Aplastic anaemia due to other external agents	0.609	0.391	0.000
D64.8 Other specified anaemias	0.608	0.392	0.000
D59.1 Other autoimmune haemolytic anaemias	0.608	0.392	0.000
D57 Sickle-cell disorders	0.605	0.395	0.000
D84 Other immunodeficiencies	0.604	0.396	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.604	0.396	0.000
E05.8 Other thyrotoxicosis	0.600	0.400	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.597	0.402	0.000
M14.4 Arthropathy in amyloidosis	0.000	0.407	0.593
M14.3 Lipoid dermatoarthritis	0.000	0.407	0.593
M14.1 Crystal arthropathy in other metabolic disorders	0.000	0.407	0.593
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.000	0.407	0.593
D89.2 Hypergammaglobulinaemia, unspecified	0.592	0.408	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.409	0.590
G36 Other acute disseminated demyelination	0.581	0.419	0.000
G37.5 Concentric sclerosis [Balo]	0.580	0.420	0.000
G37.4 Subacute necrotising myelitis	0.580	0.420	0.000
G37.2 Central pontine myelinolysis	0.580	0.420	0.000
G37.1 Central demyelination of corpus callosum	0.580	0.420	0.000
G37.0 Diffuse sclerosis	0.580	0.420	0.000
D55 Anaemia due to enzyme disorders	0.577	0.422	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.575	0.425	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.571	0.429	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.437	0.563
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.437	0.563
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.437	0.563
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.437	0.563
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.437	0.563
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.437	0.563
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.437	0.563
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.437	0.563
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.437	0.563
M12.3 Palindromic rheumatism	0.000	0.442	0.558
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.443	0.557
D69.9 Haemorrhagic condition, unspecified	0.548	0.451	0.000
R31 Unspecified haematuria	0.000	0.451	0.549
M12.2 Villonodular synovitis (pigmented)	0.000	0.455	0.545
D50.1 Sideropenic dysphagia	0.542	0.458	0.000
D69.2 Other nonthrombocytopenic purpura	0.537	0.462	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.536	0.464	0.000
E27.1 Primary adrenocortical insufficiency	0.529	0.471	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.472	0.528
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.472	0.528
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.472	0.528
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.472	0.528
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.472	0.528
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.472	0.528
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.472	0.528
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.472	0.528
M12.4 Intermittent hydrarthrosis	0.000	0.475	0.525
M12.1 Kaschin-Beck disease	0.000	0.475	0.525
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.475	0.525
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.484	0.516
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.486	0.514
M06.28 Rheumatoid bursitis (Other)	0.000	0.486	0.514
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.486	0.514
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.486	0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.486	0.514
M06.24 Rheumatoid bursitis (Hand)	0.000	0.486	0.514
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.486	0.514
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.486	0.514
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.486	0.514
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.486	0.514
M05.09 Felty's syndrome (Site unspecified)	0.000	0.486	0.514
M05.08 Felty's syndrome (Other)	0.000	0.486	0.514
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.486	0.514
M05.06 Felty's syndrome (Lower leg)	0.000	0.486	0.514
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.486	0.514
M05.04 Felty's syndrome (Hand)	0.000	0.486	0.514
M05.03 Felty's syndrome (Forearm)	0.000	0.486	0.514
M05.02 Felty's syndrome (Upper arm)	0.000	0.486	0.514
M05.01 Felty's syndrome (Shoulder region)	0.000	0.486	0.514
M05.00 Felty's syndrome (Multiple sites)	0.000	0.486	0.514
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.486	0.514
M05.18 Rheumatoid lung disease (Other)	0.000	0.486	0.514
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.486	0.514
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.486	0.514
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.486	0.514
M05.14 Rheumatoid lung disease (Hand)	0.000	0.486	0.514
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.486	0.514
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.486	0.514
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.486	0.514
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.486	0.514
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.486	0.514
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.486	0.514
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.486	0.514
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.486	0.514
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.486	0.514
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.486	0.514
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.486	0.514
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.486	0.514
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.486	0.514
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.486	0.514
D81.9 Combined immunodeficiency, unspecified	0.514	0.486	0.000
D81.8 Other combined immunodeficiencies	0.514	0.486	0.000
D81.7 Major histocompatibility complex class II deficiency	0.514	0.486	0.000
D81.6 Major histocompatibility complex class I deficiency	0.514	0.486	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.514	0.486	0.000
D81.4 Nezelof's syndrome	0.514	0.486	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.514	0.486	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.514	0.486	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.514	0.486	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.514	0.486	0.000
M08.9 Juvenile arthritis, unspecified	0.000	0.486	0.514
M08.8 Other juvenile arthritis	0.000	0.486	0.514
M08.4 Pauciarticular juvenile arthritis	0.000	0.486	0.514
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.486	0.514
M08.2 Juvenile arthritis with systemic onset	0.000	0.486	0.514
M08.1 Juvenile ankylosing spondylitis	0.000	0.486	0.514
M08.0 Juvenile rheumatoid arthritis	0.000	0.486	0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.486	0.514
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.486	0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.486	0.514
M09.0 Juvenile arthritis in psoriasis	0.000	0.486	0.514
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.000	0.490	0.509
D50.9 Iron deficiency anaemia, unspecified	0.503	0.497	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.497	0.503
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.497	0.503
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.497	0.503
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.497	0.503
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.497	0.503
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.497	0.503
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.497	0.503
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.497	0.503
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.497	0.503
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.497	0.503
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.497	0.503
M07.18 Arthritis mutilans (Other)	0.000	0.497	0.503
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.497	0.503
M07.16 Arthritis mutilans (Lower leg)	0.000	0.497	0.503
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.497	0.503
M07.14 Arthritis mutilans (Hand)	0.000	0.497	0.503
M07.13 Arthritis mutilans (Forearm)	0.000	0.497	0.503
M07.12 Arthritis mutilans (Upper arm)	0.000	0.497	0.503
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.497	0.503
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.497	0.503
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.497	0.503
M07.28 Psoriatic spondylitis (Other)	0.000	0.497	0.503
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.497	0.503
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.497	0.503
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.497	0.503
M07.24 Psoriatic spondylitis (Hand)	0.000	0.497	0.503
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.497	0.503
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.497	0.503
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.497	0.503
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.497	0.503
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.497	0.503
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.497	0.503
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.497	0.503
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.497	0.503
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.497	0.503
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.497	0.503
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.497	0.503
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.497	0.503
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.497	0.503
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.497	0.503
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.497	0.503
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.497	0.503
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.497	0.503
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.497	0.503
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.497	0.503
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.497	0.503
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.497	0.503
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.497	0.503
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.497	0.503
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.497	0.503
M12.5 Traumatic arthropathy	0.000	0.497	0.503
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.498	0.502
D68.9 Coagulation defect, unspecified	0.497	0.502	0.000
D59.8 Other acquired haemolytic anaemias	0.497	0.503	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.497	0.503	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.497	0.503	0.000
D59.3 Haemolytic-uraemic syndrome	0.497	0.503	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.497	0.503	0.000
M07.68 Other enteropathic arthropathies (Other)	0.000	0.505	0.495
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.505	0.495
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.505	0.495
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.505	0.495
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.505	0.495
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.505	0.495
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.505	0.495
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.505	0.495
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.505	0.495
D59.4 Other nonautoimmune haemolytic anaemias	0.492	0.508	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.489	0.511	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.514	0.486
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.517	0.483
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.519	0.481
M06.18 Adult-onset Still's disease (Other)	0.000	0.519	0.481
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.519	0.481
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.519	0.481
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.519	0.481
M06.14 Adult-onset Still's disease (Hand)	0.000	0.519	0.481
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.519	0.481
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.519	0.481
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.519	0.481
D82.9 Immunodeficiency associated with major defect, unspecified	0.479	0.521	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.479	0.521	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.479	0.521	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.479	0.521	0.000
D82.2 Immunodeficiency with short-limbed stature	0.479	0.521	0.000
D82.0 Wiskott-Aldrich syndrome	0.479	0.521	0.000
M11 Other crystal arthropathies	0.000	0.521	0.479
M14.8 Arthropathies in other specified diseases classified elsewhere	0.000	0.521	0.478
M05.28 Rheumatoid vasculitis (Other)	0.000	0.522	0.478
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.522	0.478
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.522	0.478
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.522	0.478
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.522	0.478
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.522	0.478
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.522	0.478
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.522	0.478
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.522	0.478
D83.8 Other common variable immunodeficiencies	0.477	0.523	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.477	0.523	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.477	0.523	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.477	0.523	0.000
D56.9 Thalassaemia, unspecified	0.475	0.525	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.471	0.529	0.000
D53.8 Other specified nutritional anaemias	0.467	0.533	0.000
D53.2 Scorbutic anaemia	0.467	0.533	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.467	0.533	0.000
D53.0 Protein deficiency anaemia	0.467	0.533	0.000
D64.4 Congenital dyserythropoietic anaemia	0.463	0.537	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.463	0.537	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.463	0.537	0.000
D64.0 Hereditary sideroblastic anaemia	0.463	0.537	0.000
D57.1 Sickle-cell anaemia without crisis	0.461	0.538	0.000
E27 Other disorders of adrenal gland	0.457	0.543	0.000
D56.1 Beta thalassaemia	0.452	0.548	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.000	0.549	0.451
D56.3 Thalassaemia trait	0.448	0.552	0.000
D56.8 Other thalassaemias	0.444	0.556	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.444	0.556	0.000
D56.2 Delta-beta thalassaemia	0.444	0.556	0.000
D56.0 Alpha thalassaemia	0.444	0.556	0.000
D84.1 Defects in the complement system	0.443	0.557	0.000
D61.1 Drug-induced aplastic anaemia	0.438	0.562	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.565	0.434
D57.8 Other sickle-cell disorders	0.434	0.566	0.000
D57.3 Sickle-cell trait	0.434	0.566	0.000
D57.2 Double heterozygous sickling disorders	0.434	0.566	0.000
D57.0 Sickle-cell anaemia with crisis	0.434	0.566	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.433	0.567	0.000
D60.8 Other acquired pure red cell aplasias	0.433	0.567	0.000
D60.1 Transient acquired pure red cell aplasia	0.433	0.567	0.000
D60.0 Chronic acquired pure red cell aplasia	0.433	0.567	0.000
L40-L45 Papulosquamous disorders	0.005	0.567	0.428
D82.1 Di George's syndrome	0.430	0.570	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.572	0.428
D83.9 Common variable immunodeficiency, unspecified	0.424	0.575	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.000	0.579	0.420
D64.3 Other sideroblastic anaemias	0.420	0.580	0.000
E20-E35 Disorders of other endocrine glands	0.418	0.582	0.000
G36.9 Acute disseminated demyelination, unspecified	0.417	0.583	0.000
G36.8 Other specified acute disseminated demyelination	0.417	0.583	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.417	0.583	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.000	0.585	0.415
D55.9 Anaemia due to enzyme disorder, unspecified	0.414	0.586	0.000
D55.8 Other anaemias due to enzyme disorders	0.414	0.586	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.414	0.586	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.414	0.586	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.414	0.586	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.414	0.586	0.000
D58 Other hereditary haemolytic anaemias	0.411	0.589	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.409	0.590	0.000
D84.8 Other specified immunodeficiencies	0.408	0.591	0.000
M13 Other arthritis	0.000	0.596	0.404
D53.9 Nutritional anaemia, unspecified	0.404	0.596	0.000
E22 Hyperfunction of pituitary gland	0.402	0.598	0.000
M12.38 Palindromic rheumatism (Other)	0.000	0.600	0.400
M12.37 Palindromic rheumatism (Ankle and foot)	0.000	0.600	0.400
M12.36 Palindromic rheumatism (Lower leg)	0.000	0.600	0.400
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.000	0.600	0.400
M12.34 Palindromic rheumatism (Hand)	0.000	0.600	0.400
M12.33 Palindromic rheumatism (Forearm)	0.000	0.600	0.400
M12.32 Palindromic rheumatism (Upper arm)	0.000	0.600	0.400
M12.31 Palindromic rheumatism (Shoulder region)	0.000	0.600	0.400
D80 Immunodeficiency with predominantly antibody defects	0.399	0.600	0.000
E27.2 Addisonian crisis	0.398	0.602	0.000
G36.0 Neuromyelitis optica [Devic]	0.392	0.608	0.000
E00-E07 Disorders of thyroid gland	0.392	0.608	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.000	0.609	0.391
M12.28 Villonodular synovitis (pigmented) (Other)	0.000	0.609	0.391
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.000	0.609	0.391
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.000	0.609	0.391
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.000	0.609	0.391
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.000	0.609	0.391
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.000	0.609	0.391
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.000	0.609	0.391
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.000	0.624	0.376
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.000	0.624	0.376
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.000	0.624	0.376
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.000	0.624	0.376
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.000	0.624	0.376
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.000	0.624	0.376
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.000	0.624	0.376
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.000	0.624	0.376
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.000	0.624	0.376
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.000	0.624	0.376
M12.19 Kaschin-Beck disease (Site unspecified)	0.000	0.624	0.376
M12.18 Kaschin-Beck disease (Other)	0.000	0.624	0.376
M12.17 Kaschin-Beck disease (Ankle and foot)	0.000	0.624	0.376
M12.16 Kaschin-Beck disease (Lower leg)	0.000	0.624	0.376
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.000	0.624	0.376
M12.14 Kaschin-Beck disease (Hand)	0.000	0.624	0.376
M12.13 Kaschin-Beck disease (Forearm)	0.000	0.624	0.376
M12.12 Kaschin-Beck disease (Upper arm)	0.000	0.624	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations